#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q14493	intact:EBI-2696427	intact:EBI-2696402|uniprotkb:B3KRJ5|ensembl:ENSP00000417686	-	psi-mi:slbp_human(display_long)|uniprotkb:SLBP(gene name)|psi-mi:SLBP(display_short)|uniprotkb:HBP(gene name synonym)|uniprotkb:Histone stem-loop-binding protein(gene name synonym)	psi-mi:stem_loop_rna(display_short)|psi-mi:EBI-2696427(display_long)	psi-mi:"MI:0018"(two hybrid)	Zbigniew et al. (2002)	pubmed:11782445|imex:IM-19029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:-1(in vitro)|taxid:-1(In vitro)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696275|imex:IM-19029-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0320"(ribonucleic acid)	refseq:NP_001293003.1|refseq:NP_001293004.1|refseq:NP_006518.1|ensembl:ENSG00000163950(gene)|ensembl:ENST00000489418(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071207"(histone pre-mRNA stem-loop binding)|go:"GO:0071208"(histone pre-mRNA DCP binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR026502|interpro:IPR029344|interpro:IPR038294|mint:Q14493|rcsb pdb:2KJM|rcsb pdb:4L8R|rcsb pdb:4QOZ|reactome:R-HSA-159230|reactome:R-HSA-73856|reactome:R-HSA-77588|dip:DIP-57045N	-	-	-	comment:Contains the RNase P leader at the 5′ end and two MS2-binding sites in the center, followed by the histone stem-loop.	figure legend:Fig 2B|complex-properties:SLBP in complex with stem loop RNA|comment:To select for proteins that bound to the SLBP/RNA complex rather than free SLBP, the yeast two-hybrid system was modified by introduction of a hybrid RNA containing the stem-loop structure|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/06/08	2014/10/16	rogid:Rt3HJRsfQ5SAgjMsloMR6H7Emho9606	-	intact-crc:1FFA09EE4D109121	false	sufficient binding region:199-270	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14493	uniprotkb:Q8WTR7	intact:EBI-2696402|uniprotkb:B3KRJ5|ensembl:ENSP00000417686	intact:EBI-751409|uniprotkb:Q9ULS9|uniprotkb:Q9Y4Q7|uniprotkb:A8K8T7|intact:EBI-28978826|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808	psi-mi:slbp_human(display_long)|uniprotkb:SLBP(gene name)|psi-mi:SLBP(display_short)|uniprotkb:HBP(gene name synonym)|uniprotkb:Histone stem-loop-binding protein(gene name synonym)	psi-mi:zn473_human(display_long)|uniprotkb:Zinc finger protein 100 homolog(gene name synonym)|uniprotkb:ZNF473(gene name)|psi-mi:ZNF473(display_short)|uniprotkb:KIAA1141(gene name synonym)|uniprotkb:ZFP100(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zbigniew et al. (2002)	pubmed:11782445|imex:IM-19029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696275|imex:IM-19029-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001293003.1|refseq:NP_001293004.1|refseq:NP_006518.1|ensembl:ENSG00000163950(gene)|ensembl:ENST00000489418(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071207"(histone pre-mRNA stem-loop binding)|go:"GO:0071208"(histone pre-mRNA DCP binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR026502|interpro:IPR029344|interpro:IPR038294|mint:Q14493|rcsb pdb:2KJM|rcsb pdb:4L8R|rcsb pdb:4QOZ|reactome:R-HSA-159230|reactome:R-HSA-73856|reactome:R-HSA-77588|dip:DIP-57045N	refseq:NP_001006657.1|refseq:NP_056243.1|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808|refseq:NP_001295353.1|ensembl:ENSG00000142528(gene)|ensembl:ENST00000270617(transcript)|ensembl:ENST00000391821(transcript)|ensembl:ENST00000595661(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0015030"(Cajal body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|rcsb pdb:2EMB|rcsb pdb:2EMC|rcsb pdb:2EME|rcsb pdb:2EOU|rcsb pdb:2EOX|rcsb pdb:2EOY|rcsb pdb:2EOZ|rcsb pdb:2YRH|rcsb pdb:2YRJ|rcsb pdb:2YSV|rcsb pdb:2YTD|rcsb pdb:2YTE|rcsb pdb:2YTT|rcsb pdb:2YU5|reactome:R-HSA-111367|reactome:R-HSA-212436|reactome:R-HSA-73856|reactome:R-HSA-77588	-	-	-	figure legend:Fig 2B|complex-properties:SLBP in complex with stem loop RNA|comment:To select for proteins that bound to the SLBP/RNA complex rather than free SLBP, the yeast two-hybrid system was modified by introduction of a hybrid RNA containing the stem-loop structure|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/06/08	2014/10/16	rogid:Rt3HJRsfQ5SAgjMsloMR6H7Emho9606	rogid:Tm+mqhJ8JVqLYFprsek+VYhcnOI9606	intact-crc:1FFA09EE4D109121	false	sufficient binding region:199-270	necessary binding region:312-552	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P79943	intact:EBI-2696427	intact:EBI-2696430|uniprotkb:Q24JX3	-	psi-mi:slbp1_xenla(display_long)|uniprotkb:slbp1(gene name)|psi-mi:slbp1(display_short)|uniprotkb:hbp(gene name synonym)|uniprotkb:slbp(gene name synonym)|uniprotkb:Histone stem-loop-binding protein 1(gene name synonym)	psi-mi:stem_loop_rna(display_short)|psi-mi:EBI-2696427(display_long)	psi-mi:"MI:0018"(two hybrid)	Zbigniew et al. (2002)	pubmed:11782445|imex:IM-19029	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:-1(in vitro)|taxid:-1(In vitro)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696299|imex:IM-19029-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0320"(ribonucleic acid)	refseq:NP_001081826.1|interpro:IPR038294|interpro:IPR026502|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|interpro:IPR029344	-	-	-	comment:Contains the RNase P leader at the 5′ end and two MS2-binding sites in the center, followed by the histone stem-loop.	figure legend:Fig 9A|complex-properties:SLBP in complex with stem loop RNA|data-processing:Species of xenopus not mentioned in the article.Since SLBP1 is present in only Xenopus laevis, this species has been taken|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/06/08	2014/10/16	rogid:3HcqpzhqroY3TMajSeXdmWfZRBI8355	-	intact-crc:88D1525DEDECF945	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P79943	uniprotkb:Q8WTR7	intact:EBI-2696430|uniprotkb:Q24JX3	intact:EBI-751409|uniprotkb:Q9ULS9|uniprotkb:Q9Y4Q7|uniprotkb:A8K8T7|intact:EBI-28978826|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808	psi-mi:slbp1_xenla(display_long)|uniprotkb:slbp1(gene name)|psi-mi:slbp1(display_short)|uniprotkb:hbp(gene name synonym)|uniprotkb:slbp(gene name synonym)|uniprotkb:Histone stem-loop-binding protein 1(gene name synonym)	psi-mi:zn473_human(display_long)|uniprotkb:Zinc finger protein 100 homolog(gene name synonym)|uniprotkb:ZNF473(gene name)|psi-mi:ZNF473(display_short)|uniprotkb:KIAA1141(gene name synonym)|uniprotkb:ZFP100(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zbigniew et al. (2002)	pubmed:11782445|imex:IM-19029	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696299|imex:IM-19029-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001081826.1|interpro:IPR038294|interpro:IPR026502|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|interpro:IPR029344	refseq:NP_001006657.1|refseq:NP_056243.1|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808|refseq:NP_001295353.1|ensembl:ENSG00000142528(gene)|ensembl:ENST00000270617(transcript)|ensembl:ENST00000391821(transcript)|ensembl:ENST00000595661(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0015030"(Cajal body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|rcsb pdb:2EMB|rcsb pdb:2EMC|rcsb pdb:2EME|rcsb pdb:2EOU|rcsb pdb:2EOX|rcsb pdb:2EOY|rcsb pdb:2EOZ|rcsb pdb:2YRH|rcsb pdb:2YRJ|rcsb pdb:2YSV|rcsb pdb:2YTD|rcsb pdb:2YTE|rcsb pdb:2YTT|rcsb pdb:2YU5|reactome:R-HSA-111367|reactome:R-HSA-212436|reactome:R-HSA-73856|reactome:R-HSA-77588	-	-	-	figure legend:Fig 9A|complex-properties:SLBP in complex with stem loop RNA|data-processing:Species of xenopus not mentioned in the article.Since SLBP1 is present in only Xenopus laevis, this species has been taken|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/06/08	2014/10/16	rogid:3HcqpzhqroY3TMajSeXdmWfZRBI8355	rogid:Tm+mqhJ8JVqLYFprsek+VYhcnOI9606	intact-crc:88D1525DEDECF945	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WTR7	ddbj/embl/genbank:M17910	intact:EBI-751409|uniprotkb:Q9ULS9|uniprotkb:Q9Y4Q7|uniprotkb:A8K8T7|intact:EBI-28978826|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808	intact:EBI-2696446	psi-mi:zn473_human(display_long)|uniprotkb:Zinc finger protein 100 homolog(gene name synonym)|uniprotkb:ZNF473(gene name)|psi-mi:ZNF473(display_short)|uniprotkb:KIAA1141(gene name synonym)|uniprotkb:ZFP100(gene name synonym)	psi-mi:u7_human_snrna(display_short)|psi-mi:M17910(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Zbigniew et al. (2002)	pubmed:11782445|imex:IM-19029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696290|imex:IM-19029-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0607"(small nuclear rna)	refseq:NP_001006657.1|refseq:NP_056243.1|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808|refseq:NP_001295353.1|ensembl:ENSG00000142528(gene)|ensembl:ENST00000270617(transcript)|ensembl:ENST00000391821(transcript)|ensembl:ENST00000595661(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0015030"(Cajal body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|rcsb pdb:2EMB|rcsb pdb:2EMC|rcsb pdb:2EME|rcsb pdb:2EOU|rcsb pdb:2EOX|rcsb pdb:2EOY|rcsb pdb:2EOZ|rcsb pdb:2YRH|rcsb pdb:2YRJ|rcsb pdb:2YSV|rcsb pdb:2YTD|rcsb pdb:2YTE|rcsb pdb:2YTT|rcsb pdb:2YU5|reactome:R-HSA-111367|reactome:R-HSA-212436|reactome:R-HSA-73856|reactome:R-HSA-77588	-	-	-	-	figure legend:Fig 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/06/08	2014/10/16	rogid:Tm+mqhJ8JVqLYFprsek+VYhcnOI9606	-	intact-crc:E82BA21A915A6901	false	-	-	-	-	psi-mi:"MI:0929"(northern blot)	psi-mi:"MI:0929"(northern blot)
uniprotkb:Q8WTR7	entrezgene/locuslink:100147744	intact:EBI-751409|uniprotkb:Q9ULS9|uniprotkb:Q9Y4Q7|uniprotkb:A8K8T7|intact:EBI-28978826|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808	intact:EBI-2696321	psi-mi:zn473_human(display_long)|uniprotkb:Zinc finger protein 100 homolog(gene name synonym)|uniprotkb:ZNF473(gene name)|psi-mi:ZNF473(display_short)|uniprotkb:KIAA1141(gene name synonym)|uniprotkb:ZFP100(gene name synonym)	psi-mi:rnu7_human(display_short)|psi-mi:100147744(display_long)|uniprotkb:U7.1(gene name synonym)|uniprotkb:RNU7-1(gene name synonym)|uniprotkb:RNU7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Zbigniew et al. (2002)	pubmed:11782445|imex:IM-19029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2696326|imex:IM-19029-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0320"(ribonucleic acid)	refseq:NP_001006657.1|refseq:NP_056243.1|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808|refseq:NP_001295353.1|ensembl:ENSG00000142528(gene)|ensembl:ENST00000270617(transcript)|ensembl:ENST00000391821(transcript)|ensembl:ENST00000595661(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0015030"(Cajal body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|rcsb pdb:2EMB|rcsb pdb:2EMC|rcsb pdb:2EME|rcsb pdb:2EOU|rcsb pdb:2EOX|rcsb pdb:2EOY|rcsb pdb:2EOZ|rcsb pdb:2YRH|rcsb pdb:2YRJ|rcsb pdb:2YSV|rcsb pdb:2YTD|rcsb pdb:2YTE|rcsb pdb:2YTT|rcsb pdb:2YU5|reactome:R-HSA-111367|reactome:R-HSA-212436|reactome:R-HSA-73856|reactome:R-HSA-77588	-	-	-	-	figure legend:Fig 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/06/08	2021/11/17	rogid:Tm+mqhJ8JVqLYFprsek+VYhcnOI9606	-	intact-crc:BF53E8A28E21621E	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)