#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O35324	uniprotkb:Q9QUM4	intact:EBI-8022357|uniprotkb:Q8C268|intact:MINT-5312801	intact:EBI-7910086|intact:MINT-205762|uniprotkb:Q9QXZ3|ensembl:ENSMUSP00000015460	psi-mi:sh21b_mouse(display_long)|uniprotkb:Eat2a(gene name synonym)|uniprotkb:Sh2d1b(gene name)|psi-mi:Sh2d1b(display_short)|uniprotkb:Eat2(gene name synonym)|uniprotkb:Sh2d1b1(gene name synonym)|uniprotkb:EWS/FLI1-activated transcript 2(gene name synonym)	psi-mi:slaf1_mouse(display_long)|uniprotkb:SLAM family member 1(gene name synonym)|uniprotkb:Slam(gene name synonym)|uniprotkb:Slamf1(gene name)|psi-mi:Slamf1(display_short)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Morra et al. (2001)	pubmed:11689425|mint:MINT-6731361	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8022354|mint:MINT-8031849	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1I3Z|interpro:IPR000980(SH2 motif)|interpro:IPR035049|interpro:IPR036860|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002366"(leukocyte activation involved in immune response)|go:"GO:0002717"(positive regulation of natural killer cell mediated immunity)|go:"GO:0002769"(natural killer cell inhibitory signaling pathway)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|mint:MINT-8031850(identity)|uniprotkb:O35324(original identifier)	refseq:NP_038758.2|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2000349"(negative regulation of CD40 signaling pathway)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|go:"GO:2000556"(positive regulation of T-helper 1 cell cytokine production)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010407(Signaling lymphocytic activation molecule, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q9QUM4|go:"GO:0009986"(cell surface)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031338"(regulation of vesicle fusion)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|ensembl:ENSMUSG00000015316(gene)|ensembl:ENSMUST00000015460(transcript)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0001787"(natural killer cell proliferation)|go:"GO:0002232"(leukocyte chemotaxis involved in inflammatory response)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002277"(myeloid dendritic cell activation involved in immune response)|go:"GO:0002725"(negative regulation of T cell cytokine production)|go:"GO:0006909"(phagocytosis)|go:"GO:0007155"(cell adhesion)|go:"GO:0009897"(external side of plasma membrane)|mint:MINT-8031853(identity)|uniprotkb:Q9QUM4(original identifier)	-	comment:mint|function:Plays a role in controlling signal transduction through at least four receptors, CD84, CD150, CD229 and CD244, expressed on the surface of professional antigen-presenting cells	function:"High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates"|comment:mint	comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:bRcxf2nKJ12OloTApJ64J3h9U6810090	rogid:yppESR3UEtf7xYxgnHNpGsRrwBw10090	intact-crc:69118790A7B0DA43|rigid:2uDbtzHu7QprDU1KAQVoiiXAMko	false	-	binding-associated region:281-294(MINT-8031856)|phosphorylated residue:288-288(MINT-8031858)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O35324	uniprotkb:Q9QUM4	intact:EBI-8022357|uniprotkb:Q8C268|intact:MINT-5312801	intact:EBI-7910086|intact:MINT-205762|uniprotkb:Q9QXZ3|ensembl:ENSMUSP00000015460	psi-mi:sh21b_mouse(display_long)|uniprotkb:Eat2a(gene name synonym)|uniprotkb:Sh2d1b(gene name)|psi-mi:Sh2d1b(display_short)|uniprotkb:Eat2(gene name synonym)|uniprotkb:Sh2d1b1(gene name synonym)|uniprotkb:EWS/FLI1-activated transcript 2(gene name synonym)	psi-mi:slaf1_mouse(display_long)|uniprotkb:SLAM family member 1(gene name synonym)|uniprotkb:Slam(gene name synonym)|uniprotkb:Slamf1(gene name)|psi-mi:Slamf1(display_short)	psi-mi:"MI:0018"(two hybrid)	Morra et al. (2001)	pubmed:11689425|mint:MINT-6731361	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8022427|mint:MINT-8031864	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1I3Z|interpro:IPR000980(SH2 motif)|interpro:IPR035049|interpro:IPR036860|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002366"(leukocyte activation involved in immune response)|go:"GO:0002717"(positive regulation of natural killer cell mediated immunity)|go:"GO:0002769"(natural killer cell inhibitory signaling pathway)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|mint:MINT-8031865(identity)|uniprotkb:O35324(original identifier)	refseq:NP_038758.2|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2000349"(negative regulation of CD40 signaling pathway)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|go:"GO:2000556"(positive regulation of T-helper 1 cell cytokine production)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010407(Signaling lymphocytic activation molecule, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q9QUM4|go:"GO:0009986"(cell surface)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031338"(regulation of vesicle fusion)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|ensembl:ENSMUSG00000015316(gene)|ensembl:ENSMUST00000015460(transcript)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0001787"(natural killer cell proliferation)|go:"GO:0002232"(leukocyte chemotaxis involved in inflammatory response)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002277"(myeloid dendritic cell activation involved in immune response)|go:"GO:0002725"(negative regulation of T cell cytokine production)|go:"GO:0006909"(phagocytosis)|go:"GO:0007155"(cell adhesion)|go:"GO:0009897"(external side of plasma membrane)|mint:MINT-8031868(identity)|uniprotkb:Q9QUM4(original identifier)	-	comment:mint|function:Plays a role in controlling signal transduction through at least four receptors, CD84, CD150, CD229 and CD244, expressed on the surface of professional antigen-presenting cells	function:"High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates"|comment:mint	comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:bRcxf2nKJ12OloTApJ64J3h9U6810090	rogid:yppESR3UEtf7xYxgnHNpGsRrwBw10090	intact-crc:09185A84612852B6|rigid:2uDbtzHu7QprDU1KAQVoiiXAMko	false	-	phosphorylated residue:288-288(MINT-8031873)|binding-associated region:281-294(MINT-8031871)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)