#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P35329 uniprotkb:P29351 intact:EBI-300059|uniprotkb:Q9JHL2|uniprotkb:Q9JJX9|uniprotkb:Q9JJY0|uniprotkb:Q9JJY1|uniprotkb:Q9R056|uniprotkb:Q9R094|uniprotkb:Q9WU51 intact:EBI-2620699|uniprotkb:Q9QVA8|uniprotkb:Q9R0V6|uniprotkb:O35128|uniprotkb:Q63872|uniprotkb:Q63873|uniprotkb:Q63874|uniprotkb:Q921G3|uniprotkb:Q9QVA6|uniprotkb:Q9QVA7|ensembl:ENSMUSP00000108103 psi-mi:cd22_mouse(display_long)|uniprotkb:Cd22(gene name)|psi-mi:Cd22(display_short)|uniprotkb:Lyb-8(gene name synonym)|uniprotkb:Sialic acid-binding Ig-like lectin 2(gene name synonym)|uniprotkb:T-cell surface antigen Leu-14(gene name synonym)|uniprotkb:B-lymphocyte cell adhesion molecule(gene name synonym)|uniprotkb:Siglec2(gene name synonym) psi-mi:ptn6_mouse(display_long)|uniprotkb:Ptpn6(gene name)|psi-mi:Ptpn6(display_short)|uniprotkb:Hcp(gene name synonym)|uniprotkb:Hcph(gene name synonym)|uniprotkb:Ptp1C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:70Z-SHP(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:PTPTY-42(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Otipoby et al. (2001) pubmed:11551923|mint:MINT-7029816|doi:10.1074/jbc.M105446200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7966993|mint:MINT-8026110 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0005769"(early endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015026"(coreceptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033691"(sialic acid binding)|go:"GO:0042113"(B cell activation)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050859"(negative regulation of B cell receptor signaling pathway)|go:"GO:0055037"(recycling endosome)|refseq:NP_001036782.1|refseq:NP_033975.3|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|refseq:XP_006539556.1|refseq:XP_006539557.1|interpro:IPR036179|reactome:R-MMU-198933|reactome:R-MMU-5690714|reactome:R-MMU-983695|mint:MINT-8026114(identity)|uniprotkb:P35329(original identifier) refseq:NP_001071173.1|refseq:NP_038573.2|ensembl:ENSMUSG00000004266(gene)|ensembl:ENSMUST00000112484(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002924"(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1905867"(epididymis development)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P29351|reactome:R-MMU-114604|reactome:R-MMU-1433559|reactome:R-MMU-210990|reactome:R-MMU-388841|reactome:R-MMU-389948|reactome:R-MMU-432142|reactome:R-MMU-512988|reactome:R-MMU-5690714|reactome:R-MMU-6798695|reactome:R-MMU-877300|reactome:R-MMU-909733|reactome:R-MMU-912526|reactome:R-MMU-912694|reactome:R-MMU-983695|go:"GO:0046703"(natural killer cell lectin-like receptor binding)|dip:DIP-41455N|mint:MINT-8026111(identity)|uniprotkb:P29351(original identifier) - - - comment:mint|partial coverage:partial coverage taxid:-3(unknown)|taxid:-3(Unknown) - 2010/09/28 2014/10/16 rogid:G3TJTROpwehqmpb+7OjLe3e+YCc10090 rogid:7dtH2jT68TwvCkZu9rqVowIrEK010090 intact-crc:F4A8360900FA4483|rigid:wrrVEGWnXrP/h58jAlXSG8+Fp20 false binding-associated region:850-862(MINT-8026117)|phosphorylated residue:857-857(MINT-8026119) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35329 uniprotkb:Q60631 intact:EBI-300059|uniprotkb:Q9JHL2|uniprotkb:Q9JJX9|uniprotkb:Q9JJY0|uniprotkb:Q9JJY1|uniprotkb:Q9R056|uniprotkb:Q9R094|uniprotkb:Q9WU51 intact:EBI-1688|uniprotkb:Q61240|ensembl:ENSMUSP00000021090|ensembl:ENSMUSP00000102106 psi-mi:cd22_mouse(display_long)|uniprotkb:Cd22(gene name)|psi-mi:Cd22(display_short)|uniprotkb:Lyb-8(gene name synonym)|uniprotkb:Sialic acid-binding Ig-like lectin 2(gene name synonym)|uniprotkb:T-cell surface antigen Leu-14(gene name synonym)|uniprotkb:B-lymphocyte cell adhesion molecule(gene name synonym)|uniprotkb:Siglec2(gene name synonym) psi-mi:grb2_mouse(display_long)|uniprotkb:Grb2(gene name)|psi-mi:Grb2(display_short)|uniprotkb:Adapter protein GRB2(gene name synonym)|uniprotkb:SH2/SH3 adapter GRB2(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Otipoby et al. (2001) pubmed:11551923|mint:MINT-7029816|doi:10.1074/jbc.M105446200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7967010|mint:MINT-8032221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0005769"(early endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015026"(coreceptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033691"(sialic acid binding)|go:"GO:0042113"(B cell activation)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050859"(negative regulation of B cell receptor signaling pathway)|go:"GO:0055037"(recycling endosome)|refseq:NP_001036782.1|refseq:NP_033975.3|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|refseq:XP_006539556.1|refseq:XP_006539557.1|interpro:IPR036179|reactome:R-MMU-198933|reactome:R-MMU-5690714|reactome:R-MMU-983695|mint:MINT-8032225(identity)|uniprotkb:P35329(original identifier) refseq:NP_032189.1|refseq:NP_001300865.1|refseq:NP_001300866.1|dip:DIP-259N|ensembl:ENSMUSG00000059923(gene)|ensembl:ENSMUST00000021090(transcript)|ensembl:ENSMUST00000106497(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007568"(aging)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031623"(receptor internalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0070436"(Grb2-EGFR complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035641|interpro:IPR035643|interpro:IPR036028|interpro:IPR036860|mint:Q60631|rcsb pdb:1GBQ|rcsb pdb:1GBR|rcsb pdb:2GBQ|rcsb pdb:3GBQ|rcsb pdb:4GBQ|reactome:R-MMU-109704|reactome:R-MMU-112412|reactome:R-MMU-1250347|reactome:R-MMU-1257604|reactome:R-MMU-1295596|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-167044|reactome:R-MMU-179812|reactome:R-MMU-180292|reactome:R-MMU-180336|reactome:R-MMU-182971|reactome:R-MMU-186763|reactome:R-MMU-1963640|reactome:R-MMU-1963642|reactome:R-MMU-2029482|reactome:R-MMU-210993|reactome:R-MMU-2179392|reactome:R-MMU-2424491|reactome:R-MMU-2428933|reactome:R-MMU-2730905|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-354194|reactome:R-MMU-375165|reactome:R-MMU-388841|reactome:R-MMU-389359|reactome:R-MMU-391160|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654695|reactome:R-MMU-5654699|reactome:R-MMU-5654700|reactome:R-MMU-5654704|reactome:R-MMU-5654706|reactome:R-MMU-5654710|reactome:R-MMU-5654712|reactome:R-MMU-5654719|reactome:R-MMU-5654720|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-5663213|reactome:R-MMU-5673001|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-74749|reactome:R-MMU-74751|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8853659|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8865999|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8983432|reactome:R-MMU-9027284|reactome:R-MMU-9028731|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9607240|reactome:R-MMU-9674555|reactome:R-MMU-983695|mint:MINT-8032222(identity)|uniprotkb:Q60631(original identifier) - - - comment:mint|partial coverage:partial coverage taxid:-3(unknown)|taxid:-3(Unknown) - 2010/09/28 2014/10/16 rogid:G3TJTROpwehqmpb+7OjLe3e+YCc10090 rogid:0Zuj4toqaPeuo3snXLa7fckMXU410090 intact-crc:EEDDBF7ADDD5D32A|rigid:TfilhmkdD8E7i+zr3MODq7lRQBQ false binding-associated region:815-828(MINT-8032228)|phosphorylated residue:822-822(MINT-8032230) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35329 uniprotkb:P29351 intact:EBI-300059|uniprotkb:Q9JHL2|uniprotkb:Q9JJX9|uniprotkb:Q9JJY0|uniprotkb:Q9JJY1|uniprotkb:Q9R056|uniprotkb:Q9R094|uniprotkb:Q9WU51 intact:EBI-2620699|uniprotkb:Q9QVA8|uniprotkb:Q9R0V6|uniprotkb:O35128|uniprotkb:Q63872|uniprotkb:Q63873|uniprotkb:Q63874|uniprotkb:Q921G3|uniprotkb:Q9QVA6|uniprotkb:Q9QVA7|ensembl:ENSMUSP00000108103 psi-mi:cd22_mouse(display_long)|uniprotkb:Cd22(gene name)|psi-mi:Cd22(display_short)|uniprotkb:Lyb-8(gene name synonym)|uniprotkb:Sialic acid-binding Ig-like lectin 2(gene name synonym)|uniprotkb:T-cell surface antigen Leu-14(gene name synonym)|uniprotkb:B-lymphocyte cell adhesion molecule(gene name synonym)|uniprotkb:Siglec2(gene name synonym) psi-mi:ptn6_mouse(display_long)|uniprotkb:Ptpn6(gene name)|psi-mi:Ptpn6(display_short)|uniprotkb:Hcp(gene name synonym)|uniprotkb:Hcph(gene name synonym)|uniprotkb:Ptp1C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:70Z-SHP(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:PTPTY-42(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Otipoby et al. (2001) pubmed:11551923|mint:MINT-7029816|doi:10.1074/jbc.M105446200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7967027|mint:MINT-8034767 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0005769"(early endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015026"(coreceptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033691"(sialic acid binding)|go:"GO:0042113"(B cell activation)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050859"(negative regulation of B cell receptor signaling pathway)|go:"GO:0055037"(recycling endosome)|refseq:NP_001036782.1|refseq:NP_033975.3|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|refseq:XP_006539556.1|refseq:XP_006539557.1|interpro:IPR036179|reactome:R-MMU-198933|reactome:R-MMU-5690714|reactome:R-MMU-983695|mint:MINT-8034771(identity)|uniprotkb:P35329(original identifier) refseq:NP_001071173.1|refseq:NP_038573.2|ensembl:ENSMUSG00000004266(gene)|ensembl:ENSMUST00000112484(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002924"(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1905867"(epididymis development)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P29351|reactome:R-MMU-114604|reactome:R-MMU-1433559|reactome:R-MMU-210990|reactome:R-MMU-388841|reactome:R-MMU-389948|reactome:R-MMU-432142|reactome:R-MMU-512988|reactome:R-MMU-5690714|reactome:R-MMU-6798695|reactome:R-MMU-877300|reactome:R-MMU-909733|reactome:R-MMU-912526|reactome:R-MMU-912694|reactome:R-MMU-983695|go:"GO:0046703"(natural killer cell lectin-like receptor binding)|dip:DIP-41455N|mint:MINT-8034768(identity)|uniprotkb:P29351(original identifier) - - - comment:mint|partial coverage:partial coverage taxid:-3(unknown)|taxid:-3(Unknown) - 2010/09/28 2014/10/16 rogid:G3TJTROpwehqmpb+7OjLe3e+YCc10090 rogid:7dtH2jT68TwvCkZu9rqVowIrEK010090 intact-crc:23D894E9510EE92A|rigid:wrrVEGWnXrP/h58jAlXSG8+Fp20 false binding-associated region:830-843(MINT-8034774)|phosphorylated residue:837-837(MINT-8034776) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)