#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P15442	uniprotkb:P33892	intact:EBI-330|uniprotkb:D6VSR3|ensemblfungi:YDR283C	intact:EBI-7442|uniprotkb:D6VTV8|ensemblfungi:YGL195W	psi-mi:gcn2_yeast(display_long)|uniprotkb:GCN2(gene name)|psi-mi:GCN2(display_short)|uniprotkb:AAS1(gene name synonym)|uniprotkb:General control non-derepressible protein 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase GCN2(gene name synonym)|uniprotkb:YDR283C(locus name)	psi-mi:gcn1_yeast(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:General control non-derepressible protein 1(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym)|uniprotkb:G1318(orf name)|uniprotkb:YGL195W(locus name)	psi-mi:"MI:0018"(two hybrid)	Kubota et al. (2001)	pubmed:11350982|imex:IM-20453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2566836|imex:IM-20453-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002691|refseq:NP_010569.3|dip:DIP-2346N|ensemblfungi:YDR283C(gene)|ensemblfungi:YDR283C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0004860"(protein kinase inhibitor activity)|mint:P15442|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043621"(protein self-association)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071232"(cellular response to histidine)|go:"GO:0071264"(positive regulation of translational initiation in response to starvation)|go:"GO:0072755"(cellular response to benomyl)|go:"GO:0100002"(negative regulation of protein kinase activity by protein phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1990451"(cellular stress response to acidic pH)|interpro:IPR000719(Protein kinase, core)|interpro:IPR006575(RWD)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR016255(Serine/threonine-protein kinase, GCN2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024435|interpro:IPR036621|interpro:IPR041715|rcsb pdb:1ZXE|rcsb pdb:1ZY4|rcsb pdb:1ZY5|rcsb pdb:1ZYC|rcsb pdb:1ZYD|rcsb pdb:2YZ0|rcsb pdb:4OTM	sgd:S000003163|refseq:NP_011320.3|mint:P33892|dip:DIP-2344N|ensemblfungi:YGL195W(gene)|ensemblfungi:YGL195W_mRNA(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071264"(positive regulation of translational initiation in response to starvation)|go:"GO:0072755"(cellular response to benomyl)|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1990451"(cellular stress response to acidic pH)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR022716|interpro:IPR033173|interpro:IPR034085	-	crc64:1F56E4B046D52325	crc64:980FDD03753E9D1C	figure legend:Fig. 1, Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/02/03	2014/10/16	rogid:d8fcrr70iKA6pK9Z4yqMQsPTAWI559292	rogid:WPYtEB/xjy4g2cJFwhe+2teVYVk559292	intact-crc:6439233210BA9AE5|rigid:yBnZLt0JMVk5+H1RCdbj1D4lGSY	false	necessary binding region:1-125(IPR006575)	necessary binding region:2064-2382	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P33892	uniprotkb:P15442	intact:EBI-7442|uniprotkb:D6VTV8|ensemblfungi:YGL195W	intact:EBI-330|uniprotkb:D6VSR3|ensemblfungi:YDR283C	psi-mi:gcn1_yeast(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:General control non-derepressible protein 1(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym)|uniprotkb:G1318(orf name)|uniprotkb:YGL195W(locus name)	psi-mi:gcn2_yeast(display_long)|uniprotkb:GCN2(gene name)|psi-mi:GCN2(display_short)|uniprotkb:AAS1(gene name synonym)|uniprotkb:General control non-derepressible protein 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase GCN2(gene name synonym)|uniprotkb:YDR283C(locus name)	psi-mi:"MI:0018"(two hybrid)	Kubota et al. (2001)	pubmed:11350982|imex:IM-20453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2566851|imex:IM-20453-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003163|refseq:NP_011320.3|mint:P33892|dip:DIP-2344N|ensemblfungi:YGL195W(gene)|ensemblfungi:YGL195W_mRNA(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071264"(positive regulation of translational initiation in response to starvation)|go:"GO:0072755"(cellular response to benomyl)|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1990451"(cellular stress response to acidic pH)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR022716|interpro:IPR033173|interpro:IPR034085	sgd:S000002691|refseq:NP_010569.3|dip:DIP-2346N|ensemblfungi:YDR283C(gene)|ensemblfungi:YDR283C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0004860"(protein kinase inhibitor activity)|mint:P15442|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043621"(protein self-association)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071232"(cellular response to histidine)|go:"GO:0071264"(positive regulation of translational initiation in response to starvation)|go:"GO:0072755"(cellular response to benomyl)|go:"GO:0100002"(negative regulation of protein kinase activity by protein phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1990451"(cellular stress response to acidic pH)|interpro:IPR000719(Protein kinase, core)|interpro:IPR006575(RWD)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR016255(Serine/threonine-protein kinase, GCN2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024435|interpro:IPR036621|interpro:IPR041715|rcsb pdb:1ZXE|rcsb pdb:1ZY4|rcsb pdb:1ZY5|rcsb pdb:1ZYC|rcsb pdb:1ZYD|rcsb pdb:2YZ0|rcsb pdb:4OTM	-	crc64:980FDD03753E9D1C	crc64:1F56E4B046D52325	figure legend:Fig. 1, Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/02/03	2014/10/16	rogid:WPYtEB/xjy4g2cJFwhe+2teVYVk559292	rogid:d8fcrr70iKA6pK9Z4yqMQsPTAWI559292	intact-crc:D0820564F05C8BCF|rigid:yBnZLt0JMVk5+H1RCdbj1D4lGSY	false	necessary binding region:2048-2382	necessary binding region:1-125(IPR006575)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)