#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P53552 uniprotkb:O13539 intact:EBI-15475|uniprotkb:D6W142|ensemblfungi:YNL139C intact:EBI-30898|uniprotkb:D3DLB6|ensemblfungi:YHR167W psi-mi:tho2_yeast(display_long)|uniprotkb:RLR1(gene name synonym)|uniprotkb:THO complex subunit RLR1(gene name synonym)|uniprotkb:LDB5(gene name synonym)|uniprotkb:THO2(gene name)|psi-mi:THO2(display_short)|uniprotkb:Low dye-binding protein 5(gene name synonym)|uniprotkb:Zinc-regulated gene 13 protein(gene name synonym)|uniprotkb:ZRG13(gene name synonym)|uniprotkb:N1209(orf name)|uniprotkb:N1835(orf name)|uniprotkb:YNL139C(locus name) psi-mi:thp2_yeast(display_long)|uniprotkb:THP2(gene name)|psi-mi:THP2(display_short)|uniprotkb:YHR167W(locus name) psi-mi:"MI:0096"(pull down) Chavez et al. (2000) pubmed:11060033|imex:IM-20422 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2531086|imex:IM-20422-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005083|refseq:NP_014260.3|ensemblfungi:YNL139C(gene)|ensemblfungi:YNL139C_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR021418|interpro:IPR021726|interpro:IPR032302|interpro:IPR040007|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV|dip:DIP-6265N|mint:P53552 refseq:NP_012037.1|sgd:S000001210|dip:DIP-4246N|mint:O13539|ensemblfungi:YHR167W(gene)|ensemblfungi:YHR167W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|interpro:IPR018557|rcsb pdb:7APX|rcsb pdb:7LUV - crc64:5F1993C3726EF298 crc64:16EFA6F464507C57 figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/15 2014/10/16 rogid:C1TncamocGADLGOOJ40Zua4UkYU559292 rogid:SaTSL6jLwX1hTVCqvU8ZNR96r8U559292 intact-crc:BF01932D7137EAF8|rigid:hYFvzNUD/Uvm0/RD/5Ha7Iu0r3o false his tag:?-?|ha tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P53552 uniprotkb:P33441 intact:EBI-15475|uniprotkb:D6W142|ensemblfungi:YNL139C intact:EBI-10841|ensemblfungi:YML062C|uniprotkb:D6VZB1 psi-mi:tho2_yeast(display_long)|uniprotkb:RLR1(gene name synonym)|uniprotkb:THO complex subunit RLR1(gene name synonym)|uniprotkb:LDB5(gene name synonym)|uniprotkb:THO2(gene name)|psi-mi:THO2(display_short)|uniprotkb:Low dye-binding protein 5(gene name synonym)|uniprotkb:Zinc-regulated gene 13 protein(gene name synonym)|uniprotkb:ZRG13(gene name synonym)|uniprotkb:N1209(orf name)|uniprotkb:N1835(orf name)|uniprotkb:YNL139C(locus name) psi-mi:mft1_yeast(display_long)|uniprotkb:YML062C(locus name)|uniprotkb:MFT1(gene name)|psi-mi:MFT1(display_short)|uniprotkb:Mitochondrial fusion target protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Chavez et al. (2000) pubmed:11060033|imex:IM-20422 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2531086|imex:IM-20422-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005083|refseq:NP_014260.3|ensemblfungi:YNL139C(gene)|ensemblfungi:YNL139C_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR021418|interpro:IPR021726|interpro:IPR032302|interpro:IPR040007|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV|dip:DIP-6265N|mint:P53552 go:"GO:0006397"(mRNA processing)|ensemblfungi:YML062C(gene)|ensemblfungi:YML062C_mRNA(transcript)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR008501(Protein of unknown function DUF783)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV|refseq:NP_013649.1|sgd:S000004527|mint:P33441|dip:DIP-4537N - crc64:5F1993C3726EF298 crc64:45A775F8C1DA3E29 figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/15 2014/10/16 rogid:C1TncamocGADLGOOJ40Zua4UkYU559292 rogid:QFj+JFK+eAlExAo8oPxdoeJOpNY559292 intact-crc:BF01932D7137EAF8|rigid:hYFvzNUD/Uvm0/RD/5Ha7Iu0r3o false his tag:?-?|ha tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P53552 uniprotkb:P17629 intact:EBI-15475|uniprotkb:D6W142|ensemblfungi:YNL139C intact:EBI-8526|uniprotkb:Q03918|uniprotkb:D6VSC1|ensemblfungi:YDR138W psi-mi:tho2_yeast(display_long)|uniprotkb:RLR1(gene name synonym)|uniprotkb:THO complex subunit RLR1(gene name synonym)|uniprotkb:LDB5(gene name synonym)|uniprotkb:THO2(gene name)|psi-mi:THO2(display_short)|uniprotkb:Low dye-binding protein 5(gene name synonym)|uniprotkb:Zinc-regulated gene 13 protein(gene name synonym)|uniprotkb:ZRG13(gene name synonym)|uniprotkb:N1209(orf name)|uniprotkb:N1835(orf name)|uniprotkb:YNL139C(locus name) psi-mi:hpr1_yeast(display_long)|uniprotkb:HPR1(gene name)|psi-mi:HPR1(display_short)|uniprotkb:YDR138W(locus name)|uniprotkb:YD9302.14(orf name)|uniprotkb:Hyperrecombination protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Chavez et al. (2000) pubmed:11060033|imex:IM-20422 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2531086|imex:IM-20422-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005083|refseq:NP_014260.3|ensemblfungi:YNL139C(gene)|ensemblfungi:YNL139C_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR021418|interpro:IPR021726|interpro:IPR032302|interpro:IPR040007|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV|dip:DIP-6265N|mint:P53552 refseq:NP_010422.1|sgd:S000002545|mint:P17629|dip:DIP-6266N|ensemblfungi:YDR138W(gene)|ensemblfungi:YDR138W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR021861|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV - crc64:5F1993C3726EF298 crc64:CBD92432F099AD22 figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/15 2014/10/16 rogid:C1TncamocGADLGOOJ40Zua4UkYU559292 rogid:7P/07YrijkKMlCOGGes6+v/eLkE559292 intact-crc:BF01932D7137EAF8|rigid:hYFvzNUD/Uvm0/RD/5Ha7Iu0r3o false his tag:?-?|ha tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P33441 uniprotkb:P17629 intact:EBI-10841|ensemblfungi:YML062C|uniprotkb:D6VZB1 intact:EBI-8526|uniprotkb:Q03918|uniprotkb:D6VSC1|ensemblfungi:YDR138W psi-mi:mft1_yeast(display_long)|uniprotkb:YML062C(locus name)|uniprotkb:MFT1(gene name)|psi-mi:MFT1(display_short)|uniprotkb:Mitochondrial fusion target protein 1(gene name synonym) psi-mi:hpr1_yeast(display_long)|uniprotkb:HPR1(gene name)|psi-mi:HPR1(display_short)|uniprotkb:YDR138W(locus name)|uniprotkb:YD9302.14(orf name)|uniprotkb:Hyperrecombination protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chavez et al. (2000) pubmed:11060033|imex:IM-20422 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2531105|imex:IM-20422-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006397"(mRNA processing)|ensemblfungi:YML062C(gene)|ensemblfungi:YML062C_mRNA(transcript)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR008501(Protein of unknown function DUF783)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV|refseq:NP_013649.1|sgd:S000004527|mint:P33441|dip:DIP-4537N refseq:NP_010422.1|sgd:S000002545|mint:P17629|dip:DIP-6266N|ensemblfungi:YDR138W(gene)|ensemblfungi:YDR138W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR021861|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV - crc64:45A775F8C1DA3E29 crc64:CBD92432F099AD22 figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/15 2014/10/16 rogid:QFj+JFK+eAlExAo8oPxdoeJOpNY559292 rogid:7P/07YrijkKMlCOGGes6+v/eLkE559292 intact-crc:818BFF463392F542|rigid:gs6GsZbTmQBWyux7MoDB1xGyga4 false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P33441 uniprotkb:P53552 intact:EBI-10841|ensemblfungi:YML062C|uniprotkb:D6VZB1 intact:EBI-15475|uniprotkb:D6W142|ensemblfungi:YNL139C psi-mi:mft1_yeast(display_long)|uniprotkb:YML062C(locus name)|uniprotkb:MFT1(gene name)|psi-mi:MFT1(display_short)|uniprotkb:Mitochondrial fusion target protein 1(gene name synonym) psi-mi:tho2_yeast(display_long)|uniprotkb:RLR1(gene name synonym)|uniprotkb:THO complex subunit RLR1(gene name synonym)|uniprotkb:LDB5(gene name synonym)|uniprotkb:THO2(gene name)|psi-mi:THO2(display_short)|uniprotkb:Low dye-binding protein 5(gene name synonym)|uniprotkb:Zinc-regulated gene 13 protein(gene name synonym)|uniprotkb:ZRG13(gene name synonym)|uniprotkb:N1209(orf name)|uniprotkb:N1835(orf name)|uniprotkb:YNL139C(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chavez et al. (2000) pubmed:11060033|imex:IM-20422 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2531105|imex:IM-20422-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006397"(mRNA processing)|ensemblfungi:YML062C(gene)|ensemblfungi:YML062C_mRNA(transcript)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR008501(Protein of unknown function DUF783)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV|refseq:NP_013649.1|sgd:S000004527|mint:P33441|dip:DIP-4537N sgd:S000005083|refseq:NP_014260.3|ensemblfungi:YNL139C(gene)|ensemblfungi:YNL139C_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR021418|interpro:IPR021726|interpro:IPR032302|interpro:IPR040007|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV|dip:DIP-6265N|mint:P53552 - crc64:45A775F8C1DA3E29 crc64:5F1993C3726EF298 figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/15 2014/10/16 rogid:QFj+JFK+eAlExAo8oPxdoeJOpNY559292 rogid:C1TncamocGADLGOOJ40Zua4UkYU559292 intact-crc:818BFF463392F542|rigid:gs6GsZbTmQBWyux7MoDB1xGyga4 false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry)