#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O60880	uniprotkb:Q99704	intact:EBI-6983382|ensembl:ENSP00000360181|uniprotkb:O95386|uniprotkb:Q6FGS6|uniprotkb:O95385|intact:MINT-113697|uniprotkb:A8MSW0|uniprotkb:O95384|uniprotkb:O95383|uniprotkb:Q9UNR0	intact:EBI-1384360|uniprotkb:O43204|uniprotkb:Q53TY2|uniprotkb:Q9UHG6|ensembl:ENSP00000233668	psi-mi:sh21a_human(display_long)|uniprotkb:SH2D1A(gene name)|psi-mi:SH2D1A(display_short)|uniprotkb:DSHP(gene name synonym)|uniprotkb:SAP(gene name synonym)|uniprotkb:Signaling lymphocytic activation molecule-associated protein(gene name synonym)|uniprotkb:T-cell signal transduction molecule SAP(gene name synonym)|uniprotkb:Duncan disease SH2-protein(gene name synonym)	psi-mi:dok1_human(display_long)|uniprotkb:Downstream of tyrosine kinase 1(gene name synonym)|uniprotkb:"p62(dok)"(gene name synonym)|uniprotkb:pp62(gene name synonym)|uniprotkb:DOK1(gene name)|psi-mi:DOK1(display_short)	psi-mi:"MI:0096"(pull down)	Sylla et al. (2000)	pubmed:10852966|mint:MINT-6731220	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7298602|mint:MINT-8037441	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1D4W|rcsb pdb:1KA6|rcsb pdb:1KA7|rcsb pdb:1M27|reactome:R-HSA-198933|ensembl:ENSG00000183918(gene)|ensembl:ENST00000371139(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006959"(humoral immune response)|go:"GO:0006968"(cellular defense response)|rcsb pdb:1D4T|go:"GO:0007267"(cell-cell signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|interpro:IPR000980(SH2 motif)|interpro:IPR017289(SH2 protein 1A)|interpro:IPR035876|interpro:IPR036860|rcsb pdb:1D1Z|refseq:NP_001108409.1|refseq:NP_002342.1|dip:DIP-40768N|mint:MINT-8037442(identity)|uniprotkb:O60880(original identifier)	refseq:NP_001184189.1|refseq:NP_001372.1|refseq:NP_001305797.1|ensembl:ENSG00000115325(gene)|ensembl:ENST00000233668(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0038145"(macrophage colony-stimulating factor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037751|mint:Q99704|rcsb pdb:2V76|reactome:R-HSA-8849469|reactome:R-HSA-8853659|mint:MINT-8037445(identity)|uniprotkb:Q99704(original identifier)	-	comment:mint|function:Inhibitor of the SLAM self-association. Acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the slam cytoplasmic region|function:"Defects in SH2D1A are a cause of lymphoproliferative syndrome X-linked type 1 (XLP1) [MIM:308240]; also known as X-linked lymphoproliferative disease (XLPD) or Duncan disease. XLP is a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus (EBV). Symptoms include severe or fatal mononucleosis, acquired hypogammaglobulinemia, pancytopenia and malignant lymphoma"	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/29	2014/10/16	rogid:tJL+FA6RUPeEknwUp85WT2p0+/c9606	rogid:Pvjez+wIa3gWdY9ZYvWN6lmOM4o9606	intact-crc:E35576C4B3DC72CC|rigid:kfARgXYfOodrC5LBHWLXrBHnp/A	false	-	phosphorylated residue:449-449(MINT-8037450)|binding-associated region:442-455(MINT-8037448)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60880	uniprotkb:Q99704	intact:EBI-6983382|ensembl:ENSP00000360181|uniprotkb:O95386|uniprotkb:Q6FGS6|uniprotkb:O95385|intact:MINT-113697|uniprotkb:A8MSW0|uniprotkb:O95384|uniprotkb:O95383|uniprotkb:Q9UNR0	intact:EBI-1384360|uniprotkb:O43204|uniprotkb:Q53TY2|uniprotkb:Q9UHG6|ensembl:ENSP00000233668	psi-mi:sh21a_human(display_long)|uniprotkb:SH2D1A(gene name)|psi-mi:SH2D1A(display_short)|uniprotkb:DSHP(gene name synonym)|uniprotkb:SAP(gene name synonym)|uniprotkb:Signaling lymphocytic activation molecule-associated protein(gene name synonym)|uniprotkb:T-cell signal transduction molecule SAP(gene name synonym)|uniprotkb:Duncan disease SH2-protein(gene name synonym)	psi-mi:dok1_human(display_long)|uniprotkb:Downstream of tyrosine kinase 1(gene name synonym)|uniprotkb:"p62(dok)"(gene name synonym)|uniprotkb:pp62(gene name synonym)|uniprotkb:DOK1(gene name)|psi-mi:DOK1(display_short)	psi-mi:"MI:0019"(coimmunoprecipitation)	Sylla et al. (2000)	pubmed:10852966|mint:MINT-6731220	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7298668|mint:MINT-8037456	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1D4W|rcsb pdb:1KA6|rcsb pdb:1KA7|rcsb pdb:1M27|reactome:R-HSA-198933|ensembl:ENSG00000183918(gene)|ensembl:ENST00000371139(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006959"(humoral immune response)|go:"GO:0006968"(cellular defense response)|rcsb pdb:1D4T|go:"GO:0007267"(cell-cell signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|interpro:IPR000980(SH2 motif)|interpro:IPR017289(SH2 protein 1A)|interpro:IPR035876|interpro:IPR036860|rcsb pdb:1D1Z|refseq:NP_001108409.1|refseq:NP_002342.1|dip:DIP-40768N|mint:MINT-8037457(identity)|uniprotkb:O60880(original identifier)	refseq:NP_001184189.1|refseq:NP_001372.1|refseq:NP_001305797.1|ensembl:ENSG00000115325(gene)|ensembl:ENST00000233668(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0038145"(macrophage colony-stimulating factor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037751|mint:Q99704|rcsb pdb:2V76|reactome:R-HSA-8849469|reactome:R-HSA-8853659|mint:MINT-8037460(identity)|uniprotkb:Q99704(original identifier)	-	comment:mint|function:Inhibitor of the SLAM self-association. Acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the slam cytoplasmic region|function:"Defects in SH2D1A are a cause of lymphoproliferative syndrome X-linked type 1 (XLP1) [MIM:308240]; also known as X-linked lymphoproliferative disease (XLPD) or Duncan disease. XLP is a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus (EBV). Symptoms include severe or fatal mononucleosis, acquired hypogammaglobulinemia, pancytopenia and malignant lymphoma"	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/29	2014/10/16	rogid:tJL+FA6RUPeEknwUp85WT2p0+/c9606	rogid:Pvjez+wIa3gWdY9ZYvWN6lmOM4o9606	intact-crc:0B5F53F8A4EE1401|rigid:kfARgXYfOodrC5LBHWLXrBHnp/A	false	-	phosphorylated residue:449-449(MINT-8037465)|binding-associated region:442-455(MINT-8037463)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)