#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O15117 uniprotkb:Q13094 intact:EBI-1753267|uniprotkb:O00359|ensembl:ENSP00000316460|ensembl:ENSP00000426346|uniprotkb:A8K2Y8|uniprotkb:E9PBV9|uniprotkb:Q9NZI9|uniprotkb:B4DLN2 intact:EBI-346946|uniprotkb:Q53XV4|uniprotkb:A8KA25|ensembl:ENSP00000046794 psi-mi:fyb1_human(display_long)|uniprotkb:FYB1(gene name)|psi-mi:FYB1(display_short)|uniprotkb:Adhesion and degranulation promoting adaptor protein(gene name synonym)|uniprotkb:FYB(gene name synonym)|uniprotkb:FYB-120/130(gene name synonym)|uniprotkb:FYN-T-binding protein(gene name synonym)|uniprotkb:SLAP-130(gene name synonym)|uniprotkb:SLAP130(gene name synonym)|uniprotkb:SLP-76-associated phosphoprotein(gene name synonym) psi-mi:lcp2_human(display_long)|uniprotkb:LCP2(gene name)|psi-mi:LCP2(display_short)|uniprotkb:SH2 domain-containing leukocyte protein of 76 kDa(gene name synonym)|uniprotkb:SLP-76 tyrosine phosphoprotein(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Boerth et al. (2000) pubmed:10671560|mint:MINT-6731165 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7199407|mint:MINT-8037013 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512310.1|refseq:XP_011512311.1|refseq:XP_011512312.1|refseq:NP_955367.1|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR029294|interpro:IPR030635|interpro:IPR035540|interpro:IPR036028|interpro:IPR043443|mint:O15117|rcsb pdb:1RI9|rcsb pdb:2GTJ|rcsb pdb:2GTO|reactome:R-HSA-202433|reactome:R-HSA-391160|ensembl:ENSG00000082074(gene)|ensembl:ENST00000351578(transcript)|ensembl:ENST00000515010(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050852"(T cell receptor signaling pathway)|refseq:NP_001230022.1|refseq:NP_001456.3|refseq:XP_006714527.1|refseq:XP_006714528.1|refseq:XP_006714529.1|dip:DIP-42204N|mint:MINT-8037017(identity)|uniprotkb:O15117(original identifier) refseq:NP_005556.1|dip:DIP-31812N|ensembl:ENSG00000043462(gene)|ensembl:ENST00000046794(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036398"(TCR signalosome)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045576"(mast cell activation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000980(SH2 motif)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036860|mint:Q13094|rcsb pdb:1H3H|rcsb pdb:1YWO|rcsb pdb:2EAP|rcsb pdb:2ROR|rcsb pdb:6ZCJ|reactome:R-HSA-114604|reactome:R-HSA-202433|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-2871809|mint:MINT-8037014(identity)|uniprotkb:Q13094(original identifier) - - - comment:homomint|comment:mint|partial coverage:partial coverage taxid:-3(unknown)|taxid:-3(Unknown) - 2010/09/29 2014/10/16 rogid:ObeGCVefTolMBQGVT/WhglH5F009606 rogid:lZa+nAuqvGDrNe3Jhxn/JQaU5ug9606 intact-crc:577DAE6EB722012C|rigid:9rbdQztv+wREwsFELtQU6pI1u+E false phosphorylated residue:559-559(MINT-8037022)|binding-associated region:552-565(MINT-8037020) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15117 uniprotkb:Q13094 intact:EBI-1753267|uniprotkb:O00359|ensembl:ENSP00000316460|ensembl:ENSP00000426346|uniprotkb:A8K2Y8|uniprotkb:E9PBV9|uniprotkb:Q9NZI9|uniprotkb:B4DLN2 intact:EBI-346946|uniprotkb:Q53XV4|uniprotkb:A8KA25|ensembl:ENSP00000046794 psi-mi:fyb1_human(display_long)|uniprotkb:FYB1(gene name)|psi-mi:FYB1(display_short)|uniprotkb:Adhesion and degranulation promoting adaptor protein(gene name synonym)|uniprotkb:FYB(gene name synonym)|uniprotkb:FYB-120/130(gene name synonym)|uniprotkb:FYN-T-binding protein(gene name synonym)|uniprotkb:SLAP-130(gene name synonym)|uniprotkb:SLAP130(gene name synonym)|uniprotkb:SLP-76-associated phosphoprotein(gene name synonym) psi-mi:lcp2_human(display_long)|uniprotkb:LCP2(gene name)|psi-mi:LCP2(display_short)|uniprotkb:SH2 domain-containing leukocyte protein of 76 kDa(gene name synonym)|uniprotkb:SLP-76 tyrosine phosphoprotein(gene name synonym) psi-mi:"MI:0096"(pull down) Boerth et al. (2000) pubmed:10671560|mint:MINT-6731165 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7199437|mint:MINT-8037028 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512310.1|refseq:XP_011512311.1|refseq:XP_011512312.1|refseq:NP_955367.1|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR029294|interpro:IPR030635|interpro:IPR035540|interpro:IPR036028|interpro:IPR043443|mint:O15117|rcsb pdb:1RI9|rcsb pdb:2GTJ|rcsb pdb:2GTO|reactome:R-HSA-202433|reactome:R-HSA-391160|ensembl:ENSG00000082074(gene)|ensembl:ENST00000351578(transcript)|ensembl:ENST00000515010(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050852"(T cell receptor signaling pathway)|refseq:NP_001230022.1|refseq:NP_001456.3|refseq:XP_006714527.1|refseq:XP_006714528.1|refseq:XP_006714529.1|dip:DIP-42204N|mint:MINT-8037032(identity)|uniprotkb:O15117(original identifier) refseq:NP_005556.1|dip:DIP-31812N|ensembl:ENSG00000043462(gene)|ensembl:ENST00000046794(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036398"(TCR signalosome)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045576"(mast cell activation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000980(SH2 motif)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036860|mint:Q13094|rcsb pdb:1H3H|rcsb pdb:1YWO|rcsb pdb:2EAP|rcsb pdb:2ROR|rcsb pdb:6ZCJ|reactome:R-HSA-114604|reactome:R-HSA-202433|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-2871809|mint:MINT-8037029(identity)|uniprotkb:Q13094(original identifier) - - - comment:homomint|comment:mint|partial coverage:partial coverage taxid:-3(unknown)|taxid:-3(Unknown) - 2010/09/29 2014/10/16 rogid:ObeGCVefTolMBQGVT/WhglH5F009606 rogid:lZa+nAuqvGDrNe3Jhxn/JQaU5ug9606 intact-crc:5F49FE6A8E29012F|rigid:9rbdQztv+wREwsFELtQU6pI1u+E false binding-associated region:552-565(MINT-8037035)|phosphorylated residue:559-559(MINT-8037037) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)