#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q14934 uniprotkb:P27348 intact:EBI-3905796|uniprotkb:B5B2V3|uniprotkb:B5B2V0|uniprotkb:B5B2W1|uniprotkb:B5B2V9|uniprotkb:B5B2V7|uniprotkb:B5B2U8|uniprotkb:B5B2W4|uniprotkb:B5B2W0|uniprotkb:B5B2W2|uniprotkb:B5B2U7|uniprotkb:B5B2W8|uniprotkb:Q96H68|uniprotkb:B5B2V5|uniprotkb:B5B2W6|uniprotkb:B5B2V4|uniprotkb:B5B2X0|uniprotkb:B5B2W5|uniprotkb:B5B2W9|uniprotkb:B5B2V2|uniprotkb:B4DDG5|uniprotkb:B5B2U9|uniprotkb:B5B2V1|uniprotkb:B5B2V8|uniprotkb:B5B2W7|uniprotkb:B4DY55|uniprotkb:B5B2W3|uniprotkb:Q7Z598|ensembl:ENSP00000250373|ensembl:ENSP00000494405 intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267 psi-mi:nfac4_human(display_long)|uniprotkb:NFATC4(gene name)|psi-mi:NFATC4(display_short)|uniprotkb:NFAT3(gene name synonym)|uniprotkb:T-cell transcription factor NFAT3(gene name synonym) psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym) psi-mi:"MI:0096"(pull down) Chow et al. (2000) pubmed:10611249|mint:MINT-8005424|doi:10.1128/MCB.20.2.702-712.2000 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7163617|mint:MINT-8005433 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011535099.1|refseq:XP_011535101.1|ensembl:ENSP00000250373|ensembl:ENST00000413692|ensembl:ENSP00000388910|ensembl:ENST00000422617|ensembl:ENSP00000396788|ensembl:ENST00000424781|ensembl:ENSP00000388668|ensembl:ENST00000539237|ensembl:ENSP00000439350|ensembl:ENST00000553469|ensembl:ENSP00000451502|ensembl:ENST00000553708|ensembl:ENSP00000450590|ensembl:ENST00000553879|ensembl:ENSP00000452349|ensembl:ENST00000554050|ensembl:ENSP00000451151|ensembl:ENST00000554344|ensembl:ENSP00000450469|ensembl:ENST00000554473|ensembl:ENSP00000450810|ensembl:ENST00000554591|ensembl:ENSP00000452039|ensembl:ENST00000554661|ensembl:ENSP00000450733|ensembl:ENST00000554966|ensembl:ENSP00000450644|ensembl:ENST00000555167|ensembl:ENSP00000451395|ensembl:ENST00000555393|ensembl:ENSP00000451801|ensembl:ENST00000555453|ensembl:ENSP00000450686|ensembl:ENST00000555590|ensembl:ENSP00000451224|ensembl:ENST00000555802|ensembl:ENSP00000451590|ensembl:ENST00000556169|ensembl:ENSP00000451454|ensembl:ENST00000556279|ensembl:ENSP00000452270|ensembl:ENST00000556759|ensembl:ENSP00000451183|ensembl:ENST00000557451|ensembl:ENSP00000451284|ensembl:ENST00000557767|ensembl:ENSP00000451496|ensembl:ENST00000642182|ensembl:ENSP00000495011|ensembl:ENSP00000494405|ensembl:ENST00000642423|ensembl:ENSP00000495052|ensembl:ENST00000642571|ensembl:ENSP00000493808|ensembl:ENST00000642650|refseq:NP_001129494.1|refseq:NP_001185894.1|refseq:NP_001185895.1|refseq:NP_001185896.1|refseq:NP_004545.2|ensembl:ENST00000643468|ensembl:ENSP00000494577|ensembl:ENST00000643679|ensembl:ENSP00000493557|ensembl:ENST00000643941|ensembl:ENSP00000493733|ensembl:ENST00000644025|ensembl:ENSP00000494705|ensembl:ENST00000644166|ensembl:ENSP00000496192|ensembl:ENST00000644182|ensembl:ENSP00000495766|ensembl:ENST00000644376|ensembl:ENSP00000493885|ensembl:ENST00000644583|ensembl:ENSP00000496733|ensembl:ENST00000644758|ensembl:ENSP00000495684|ensembl:ENST00000645116|ensembl:ENSP00000493851|ensembl:ENST00000645397|ensembl:ENSP00000493943|ensembl:ENST00000645587|ensembl:ENSP00000495213|ensembl:ENST00000645795|ensembl:ENSP00000495926|ensembl:ENST00000646023|ensembl:ENSP00000494993|ensembl:ENST00000646364|ensembl:ENSP00000496579|ensembl:ENST00000646650|ensembl:ENSP00000496777|ensembl:ENST00000646652|ensembl:ENSP00000496108|ensembl:ENST00000647017|ensembl:ENSP00000496558|ensembl:ENST00000647345|ensembl:ENSP00000493614|ensembl:ENSP00000495758|refseq:NP_001275731.1|refseq:NP_001306972.1|ensembl:ENSG00000100968(gene)|ensembl:ENSG00000285485(gene)|ensembl:ENST00000250373(transcript)|ensembl:ENST00000642302(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016607"(nuclear speck)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031547"(brain-derived neurotrophic factor receptor signaling pathway)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045333"(cellular respiration)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000297"(negative regulation of synapse maturation)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008366("Nuclear factor of activated T cells (NFAT)")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR032397|interpro:IPR037059|mint:Q14934|rcsb pdb:2YRP|mint:MINT-8005437(identity)|uniprotkb:Q14934(original identifier) refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N|mint:MINT-8005434(identity)|uniprotkb:P27348(original identifier) - - - comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:-3(unknown)|taxid:-3(Unknown) - 2010/09/21 2014/10/16 rogid:j/dzDqO4We+TxjChC8kJI5okBEE9606 rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606 intact-crc:4F9162613856D98F|rigid:dsqbDKRgyTPWXnOnF9/oiztLg54 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14934 uniprotkb:P27348 intact:EBI-3905796|uniprotkb:B5B2V3|uniprotkb:B5B2V0|uniprotkb:B5B2W1|uniprotkb:B5B2V9|uniprotkb:B5B2V7|uniprotkb:B5B2U8|uniprotkb:B5B2W4|uniprotkb:B5B2W0|uniprotkb:B5B2W2|uniprotkb:B5B2U7|uniprotkb:B5B2W8|uniprotkb:Q96H68|uniprotkb:B5B2V5|uniprotkb:B5B2W6|uniprotkb:B5B2V4|uniprotkb:B5B2X0|uniprotkb:B5B2W5|uniprotkb:B5B2W9|uniprotkb:B5B2V2|uniprotkb:B4DDG5|uniprotkb:B5B2U9|uniprotkb:B5B2V1|uniprotkb:B5B2V8|uniprotkb:B5B2W7|uniprotkb:B4DY55|uniprotkb:B5B2W3|uniprotkb:Q7Z598|ensembl:ENSP00000250373|ensembl:ENSP00000494405 intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267 psi-mi:nfac4_human(display_long)|uniprotkb:NFATC4(gene name)|psi-mi:NFATC4(display_short)|uniprotkb:NFAT3(gene name synonym)|uniprotkb:T-cell transcription factor NFAT3(gene name synonym) psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym) psi-mi:"MI:0096"(pull down) Chow et al. (2000) pubmed:10611249|mint:MINT-8005424|doi:10.1128/MCB.20.2.702-712.2000 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7163630|mint:MINT-8005440 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011535099.1|refseq:XP_011535101.1|ensembl:ENSP00000250373|ensembl:ENST00000413692|ensembl:ENSP00000388910|ensembl:ENST00000422617|ensembl:ENSP00000396788|ensembl:ENST00000424781|ensembl:ENSP00000388668|ensembl:ENST00000539237|ensembl:ENSP00000439350|ensembl:ENST00000553469|ensembl:ENSP00000451502|ensembl:ENST00000553708|ensembl:ENSP00000450590|ensembl:ENST00000553879|ensembl:ENSP00000452349|ensembl:ENST00000554050|ensembl:ENSP00000451151|ensembl:ENST00000554344|ensembl:ENSP00000450469|ensembl:ENST00000554473|ensembl:ENSP00000450810|ensembl:ENST00000554591|ensembl:ENSP00000452039|ensembl:ENST00000554661|ensembl:ENSP00000450733|ensembl:ENST00000554966|ensembl:ENSP00000450644|ensembl:ENST00000555167|ensembl:ENSP00000451395|ensembl:ENST00000555393|ensembl:ENSP00000451801|ensembl:ENST00000555453|ensembl:ENSP00000450686|ensembl:ENST00000555590|ensembl:ENSP00000451224|ensembl:ENST00000555802|ensembl:ENSP00000451590|ensembl:ENST00000556169|ensembl:ENSP00000451454|ensembl:ENST00000556279|ensembl:ENSP00000452270|ensembl:ENST00000556759|ensembl:ENSP00000451183|ensembl:ENST00000557451|ensembl:ENSP00000451284|ensembl:ENST00000557767|ensembl:ENSP00000451496|ensembl:ENST00000642182|ensembl:ENSP00000495011|ensembl:ENSP00000494405|ensembl:ENST00000642423|ensembl:ENSP00000495052|ensembl:ENST00000642571|ensembl:ENSP00000493808|ensembl:ENST00000642650|refseq:NP_001129494.1|refseq:NP_001185894.1|refseq:NP_001185895.1|refseq:NP_001185896.1|refseq:NP_004545.2|ensembl:ENST00000643468|ensembl:ENSP00000494577|ensembl:ENST00000643679|ensembl:ENSP00000493557|ensembl:ENST00000643941|ensembl:ENSP00000493733|ensembl:ENST00000644025|ensembl:ENSP00000494705|ensembl:ENST00000644166|ensembl:ENSP00000496192|ensembl:ENST00000644182|ensembl:ENSP00000495766|ensembl:ENST00000644376|ensembl:ENSP00000493885|ensembl:ENST00000644583|ensembl:ENSP00000496733|ensembl:ENST00000644758|ensembl:ENSP00000495684|ensembl:ENST00000645116|ensembl:ENSP00000493851|ensembl:ENST00000645397|ensembl:ENSP00000493943|ensembl:ENST00000645587|ensembl:ENSP00000495213|ensembl:ENST00000645795|ensembl:ENSP00000495926|ensembl:ENST00000646023|ensembl:ENSP00000494993|ensembl:ENST00000646364|ensembl:ENSP00000496579|ensembl:ENST00000646650|ensembl:ENSP00000496777|ensembl:ENST00000646652|ensembl:ENSP00000496108|ensembl:ENST00000647017|ensembl:ENSP00000496558|ensembl:ENST00000647345|ensembl:ENSP00000493614|ensembl:ENSP00000495758|refseq:NP_001275731.1|refseq:NP_001306972.1|ensembl:ENSG00000100968(gene)|ensembl:ENSG00000285485(gene)|ensembl:ENST00000250373(transcript)|ensembl:ENST00000642302(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016607"(nuclear speck)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031547"(brain-derived neurotrophic factor receptor signaling pathway)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045333"(cellular respiration)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000297"(negative regulation of synapse maturation)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008366("Nuclear factor of activated T cells (NFAT)")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR032397|interpro:IPR037059|mint:Q14934|rcsb pdb:2YRP|mint:MINT-8005444(identity)|uniprotkb:Q14934(original identifier) refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N|mint:MINT-8005441(identity)|uniprotkb:P27348(original identifier) - - - comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:-3(unknown)|taxid:-3(Unknown) - 2010/09/21 2014/10/16 rogid:j/dzDqO4We+TxjChC8kJI5okBEE9606 rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606 intact-crc:E1CCD86C82CE1311|rigid:dsqbDKRgyTPWXnOnF9/oiztLg54 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)