#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P61823	uniprotkb:P13489	intact:EBI-908364|uniprotkb:P00656|uniprotkb:Q9TSF2|uniprotkb:A6QPW8|ensembl:ENSBTAP00000011586	intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402|ensembl:ENSP00000348515|ensembl:ENSP00000380729|ensembl:ENSP00000380738|ensembl:ENSP00000380739|ensembl:ENSP00000416589|ensembl:ENSP00000433999|ensembl:ENSP00000435594|ensembl:ENSP00000478664|ensembl:ENSP00000479004|ensembl:ENSP00000479966|ensembl:ENSP00000480036|ensembl:ENSP00000484572|ensembl:ENSP00000487753|ensembl:ENSP00000487940|ensembl:ENSP00000488734	psi-mi:rnas1_bovin(display_long)|uniprotkb:RNASE1(gene name)|psi-mi:RNASE1(display_short)|uniprotkb:RNS1(gene name synonym)|uniprotkb:RNase 1(gene name synonym)|uniprotkb:RNase A(gene name synonym)	psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym)	psi-mi:"MI:0920"(ribonuclease assay)	- (1999)	pubmed:10413501|pubmed:10413501|imex:IM-20526	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0902"(rna cleavage)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2943937|imex:IM-20526-1	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001014408.2|refseq:XP_005211519.1|dip:DIP-36384N|rcsb pdb:3RID|rcsb pdb:3RN3|rcsb pdb:3RSD|rcsb pdb:3RSK|rcsb pdb:3RSP|rcsb pdb:3SRN|rcsb pdb:4AO1|rcsb pdb:4G8V|rcsb pdb:4G8Y|rcsb pdb:4G90|rcsb pdb:4J5Z|rcsb pdb:4J60|rcsb pdb:4J61|rcsb pdb:4J62|rcsb pdb:4J63|rcsb pdb:4J64|rcsb pdb:4J65|rcsb pdb:4J66|rcsb pdb:3RH1|rcsb pdb:4J67|rcsb pdb:4J68|rcsb pdb:4J6A|rcsb pdb:4K7L|rcsb pdb:4K7M|rcsb pdb:4L55|rcsb pdb:4MXF|rcsb pdb:4O36|rcsb pdb:4O37|rcsb pdb:4OKF|rcsb pdb:4OOH|rcsb pdb:4OT4|rcsb pdb:4PEQ|rcsb pdb:4POU|rcsb pdb:4QH3|rcsb pdb:4RAT|rcsb pdb:4RSD|rcsb pdb:4RSK|rcsb pdb:4RTE|rcsb pdb:4S0Q|rcsb pdb:4S18|rcsb pdb:4SRN|rcsb pdb:4WYN|rcsb pdb:4WYP|rcsb pdb:4WYZ|rcsb pdb:4YGW|rcsb pdb:4ZZ4|rcsb pdb:5D6U|rcsb pdb:5D97|rcsb pdb:5E5E|rcsb pdb:5E5F|rcsb pdb:5ET4|rcsb pdb:5JLG|rcsb pdb:5JMG|rcsb pdb:4J69|rcsb pdb:5JML|rcsb pdb:5NA9|rcsb pdb:5NJ7|rcsb pdb:5OBD|rcsb pdb:5OBE|rcsb pdb:5OGH|rcsb pdb:5OLD|rcsb pdb:5RAT|rcsb pdb:5RSA|rcsb pdb:6ETK|rcsb pdb:6ETL|rcsb pdb:6ETM|rcsb pdb:6ETN|rcsb pdb:6ETO|rcsb pdb:6ETP|rcsb pdb:6ETQ|rcsb pdb:6ETR|rcsb pdb:6F60|rcsb pdb:6GOK|rcsb pdb:6PVU|rcsb pdb:6PVV|rcsb pdb:6PVW|rcsb pdb:6PVX|rcsb pdb:6QE9|rcsb pdb:6RAT|rcsb pdb:6RSA|rcsb pdb:6XHC|rcsb pdb:6XHD|rcsb pdb:6XHE|rcsb pdb:6XHF|rcsb pdb:6XVX|rcsb pdb:6XW0|rcsb pdb:6YO1|rcsb pdb:7RAT|rcsb pdb:7RSA|rcsb pdb:8RAT|rcsb pdb:8RSA|rcsb pdb:9RAT|rcsb pdb:9RSA|rcsb pdb:5OBC|ensembl:ENSBTAG00000008793(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004522"(ribonuclease A activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016829"(lyase activity)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|mint:P61823|rcsb pdb:1A2W|rcsb pdb:1A5P|rcsb pdb:1A5Q|rcsb pdb:1AFK|rcsb pdb:1AFL|rcsb pdb:1AFU|rcsb pdb:1AQP|rcsb pdb:1B6V|rcsb pdb:1BEL|rcsb pdb:1BZQ|rcsb pdb:1C0B|rcsb pdb:1C0C|rcsb pdb:1C8W|rcsb pdb:1C9V|rcsb pdb:1C9X|rcsb pdb:1CJQ|rcsb pdb:1CJR|rcsb pdb:1D5D|rcsb pdb:1D5E|rcsb pdb:1D5H|rcsb pdb:1DFJ|rcsb pdb:1DY5|rcsb pdb:1EIC|rcsb pdb:1EID|rcsb pdb:1EIE|rcsb pdb:1EOS|rcsb pdb:1EOW|rcsb pdb:1F0V|rcsb pdb:1FEV|ensembl:ENSBTAT00000011586(transcript)|rcsb pdb:1FS3|rcsb pdb:1GV7|rcsb pdb:1IZP|rcsb pdb:1IZQ|rcsb pdb:1IZR|rcsb pdb:1J7Z|rcsb pdb:1J80|rcsb pdb:1J81|rcsb pdb:1J82|rcsb pdb:1JN4|rcsb pdb:1JS0|rcsb pdb:1JVT|rcsb pdb:1JVU|rcsb pdb:1JVV|rcsb pdb:1KF2|rcsb pdb:1KF3|rcsb pdb:1KF4|rcsb pdb:1KF5|rcsb pdb:1KF7|rcsb pdb:1KF8|rcsb pdb:1KH8|rcsb pdb:1LSQ|rcsb pdb:1O0F|rcsb pdb:1O0H|rcsb pdb:1O0M|rcsb pdb:1O0N|rcsb pdb:1O0O|rcsb pdb:1QHC|rcsb pdb:1RAR|rcsb pdb:1RAS|rcsb pdb:1RAT|rcsb pdb:1RBB|rcsb pdb:1RBC|rcsb pdb:1RBD|rcsb pdb:1RBE|rcsb pdb:1RBF|rcsb pdb:1RBG|rcsb pdb:1RBH|rcsb pdb:1RBI|rcsb pdb:1RBJ|rcsb pdb:1RBN|rcsb pdb:1RBW|rcsb pdb:1RBX|rcsb pdb:1RCA|rcsb pdb:1RCN|rcsb pdb:1RHA|rcsb pdb:1RHB|rcsb pdb:1RNC|rcsb pdb:1RND|rcsb pdb:1RNM|rcsb pdb:1RNN|rcsb pdb:1RNO|rcsb pdb:1RNQ|rcsb pdb:1RNU|rcsb pdb:1RNV|rcsb pdb:1RNW|rcsb pdb:1RNX|rcsb pdb:1RNY|rcsb pdb:1RNZ|rcsb pdb:1ROB|rcsb pdb:1RPF|rcsb pdb:1RPG|rcsb pdb:1RPH|rcsb pdb:1RSM|rcsb pdb:1RTA|rcsb pdb:1RTB|rcsb pdb:1RUV|rcsb pdb:1SRN|rcsb pdb:1SSA|rcsb pdb:1SSB|rcsb pdb:1SSC|rcsb pdb:1U1B|rcsb pdb:1UN5|rcsb pdb:1W4O|rcsb pdb:1W4P|rcsb pdb:1W4Q|rcsb pdb:1WBU|rcsb pdb:1XPS|rcsb pdb:1XPT|rcsb pdb:1YMN|rcsb pdb:1YMR|rcsb pdb:1YMW|rcsb pdb:1Z3L|rcsb pdb:1Z3M|rcsb pdb:1Z3P|rcsb pdb:1Z6D|rcsb pdb:1Z6S|rcsb pdb:2AAS|rcsb pdb:2APQ|rcsb pdb:2APU|rcsb pdb:2BLP|rcsb pdb:2BLZ|rcsb pdb:2E33|rcsb pdb:2E3W|rcsb pdb:2G4W|rcsb pdb:2G4X|rcsb pdb:2G8Q|rcsb pdb:2G8R|rcsb pdb:2NUI|rcsb pdb:2OP2|rcsb pdb:2OQF|rcsb pdb:2P42|rcsb pdb:2P43|rcsb pdb:2P44|rcsb pdb:2P45|rcsb pdb:2P46|rcsb pdb:2P47|rcsb pdb:2P48|rcsb pdb:2P49|rcsb pdb:2P4A|rcsb pdb:2QCA|rcsb pdb:2RAT|rcsb pdb:2RLN|rcsb pdb:2RNS|rcsb pdb:2W5G|rcsb pdb:2W5I|rcsb pdb:2W5K|rcsb pdb:2W5L|rcsb pdb:2W5M|rcsb pdb:2XOG|rcsb pdb:2XOI|rcsb pdb:3A1R|rcsb pdb:3D6O|rcsb pdb:3D6P|rcsb pdb:3D6Q|rcsb pdb:3D7B|rcsb pdb:3D8Y|rcsb pdb:3D8Z|rcsb pdb:3DH5|rcsb pdb:3DH6|rcsb pdb:3DI7|rcsb pdb:3DI8|rcsb pdb:3DI9|rcsb pdb:3DIB|rcsb pdb:3DIC|rcsb pdb:3DXG|rcsb pdb:3DXH|rcsb pdb:3EUX|rcsb pdb:3EUY|rcsb pdb:3EUZ|rcsb pdb:3EV0|rcsb pdb:3EV1|rcsb pdb:3EV2|rcsb pdb:3EV3|rcsb pdb:3EV4|rcsb pdb:3EV5|rcsb pdb:3EV6|rcsb pdb:3FKZ|rcsb pdb:3FL0|rcsb pdb:3FL1|rcsb pdb:3FL3|rcsb pdb:3I67|rcsb pdb:3I6F|rcsb pdb:3I6H|rcsb pdb:3I6J|rcsb pdb:3I7W|rcsb pdb:3I7X|rcsb pdb:3I7Y|rcsb pdb:3JW1|rcsb pdb:3LXO|rcsb pdb:3MWQ|rcsb pdb:3MWR|rcsb pdb:3MX8|rcsb pdb:3MZQ|rcsb pdb:3MZR|rcsb pdb:3OQY|rcsb pdb:3OQZ|rcsb pdb:3OR0|rcsb pdb:3QL1|rcsb pdb:3QL2|rcsb pdb:3QSK|rcsb pdb:3RAT	refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|refseq:XP_016873595.1|ensembl:ENST00000619599(transcript)|ensembl:ENST00000621211(transcript)|ensembl:ENST00000632527(transcript)|ensembl:ENST00000632954(transcript)|ensembl:ENST00000633287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|ensembl:ENSG00000023191(gene)|ensembl:ENSG00000276230(gene)|ensembl:ENST00000354420(transcript)|ensembl:ENST00000356187(transcript)|ensembl:ENST00000397604(transcript)|ensembl:ENST00000397614(transcript)|ensembl:ENST00000397615(transcript)|ensembl:ENST00000438658(transcript)|ensembl:ENST00000533410(transcript)|ensembl:ENST00000534797(transcript)|ensembl:ENST00000612988(transcript)|ensembl:ENST00000617351(transcript)|ensembl:ENST00000618184(transcript)	go:"GO:0004540"(ribonuclease activity)|go:"GO:0008428"(ribonuclease inhibitor activity)	-	-	kinetics:Ki=3.1E-14M. tyr438phe mutation of P13489 ki=1.2E-12M|kinetic_conditions:pH6.0, Temp=25C|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/10	2014/10/16	rogid:ifHI/UwVRIuj5ksIiZPB0pUY+0E9913	rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606	intact-crc:418145B62FA5AAA2|rigid:K+tloxjB9O3sGHEIqjWEHfb6a2I	false	-	mutation decreasing interaction:438-438	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P03950	uniprotkb:P13489	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402|ensembl:ENSP00000348515|ensembl:ENSP00000380729|ensembl:ENSP00000380738|ensembl:ENSP00000380739|ensembl:ENSP00000416589|ensembl:ENSP00000433999|ensembl:ENSP00000435594|ensembl:ENSP00000478664|ensembl:ENSP00000479004|ensembl:ENSP00000479966|ensembl:ENSP00000480036|ensembl:ENSP00000484572|ensembl:ENSP00000487753|ensembl:ENSP00000487940|ensembl:ENSP00000488734	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	- (1999)	pubmed:10413501|pubmed:10413501|imex:IM-20526	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2944843|imex:IM-20526-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|refseq:XP_016873595.1|ensembl:ENST00000619599(transcript)|ensembl:ENST00000621211(transcript)|ensembl:ENST00000632527(transcript)|ensembl:ENST00000632954(transcript)|ensembl:ENST00000633287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|ensembl:ENSG00000023191(gene)|ensembl:ENSG00000276230(gene)|ensembl:ENST00000354420(transcript)|ensembl:ENST00000356187(transcript)|ensembl:ENST00000397604(transcript)|ensembl:ENST00000397614(transcript)|ensembl:ENST00000397615(transcript)|ensembl:ENST00000438658(transcript)|ensembl:ENST00000533410(transcript)|ensembl:ENST00000534797(transcript)|ensembl:ENST00000612988(transcript)|ensembl:ENST00000617351(transcript)|ensembl:ENST00000618184(transcript)	-	-	-	kinetics:Ka=2.8E8M-1sec-1, tyr435phe mutant Ka=1.6E8M-1sec-1, tyr438phe Ka=1.5E8M-1sec-1|kinetic_conditions:pH=6.0, Temp=25C|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/10	2014/10/16	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606	intact-crc:EF482188BDFE7E46|rigid:RZ1qEz/b2CoFS4Z4Mufmwq3KAZw	false	-	mutation decreasing interaction:435-435|mutation decreasing interaction:438-438	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13489	uniprotkb:P61823	intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402|ensembl:ENSP00000348515|ensembl:ENSP00000380729|ensembl:ENSP00000380738|ensembl:ENSP00000380739|ensembl:ENSP00000416589|ensembl:ENSP00000433999|ensembl:ENSP00000435594|ensembl:ENSP00000478664|ensembl:ENSP00000479004|ensembl:ENSP00000479966|ensembl:ENSP00000480036|ensembl:ENSP00000484572|ensembl:ENSP00000487753|ensembl:ENSP00000487940|ensembl:ENSP00000488734	intact:EBI-908364|uniprotkb:P00656|uniprotkb:Q9TSF2|uniprotkb:A6QPW8|ensembl:ENSBTAP00000011586	psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym)	psi-mi:rnas1_bovin(display_long)|uniprotkb:RNASE1(gene name)|psi-mi:RNASE1(display_short)|uniprotkb:RNS1(gene name synonym)|uniprotkb:RNase 1(gene name synonym)|uniprotkb:RNase A(gene name synonym)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	- (1999)	pubmed:10413501|pubmed:10413501|imex:IM-20526	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2944707|imex:IM-20526-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|refseq:XP_016873595.1|ensembl:ENST00000619599(transcript)|ensembl:ENST00000621211(transcript)|ensembl:ENST00000632527(transcript)|ensembl:ENST00000632954(transcript)|ensembl:ENST00000633287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|ensembl:ENSG00000023191(gene)|ensembl:ENSG00000276230(gene)|ensembl:ENST00000354420(transcript)|ensembl:ENST00000356187(transcript)|ensembl:ENST00000397604(transcript)|ensembl:ENST00000397614(transcript)|ensembl:ENST00000397615(transcript)|ensembl:ENST00000438658(transcript)|ensembl:ENST00000533410(transcript)|ensembl:ENST00000534797(transcript)|ensembl:ENST00000612988(transcript)|ensembl:ENST00000617351(transcript)|ensembl:ENST00000618184(transcript)	refseq:NP_001014408.2|refseq:XP_005211519.1|dip:DIP-36384N|rcsb pdb:3RID|rcsb pdb:3RN3|rcsb pdb:3RSD|rcsb pdb:3RSK|rcsb pdb:3RSP|rcsb pdb:3SRN|rcsb pdb:4AO1|rcsb pdb:4G8V|rcsb pdb:4G8Y|rcsb pdb:4G90|rcsb pdb:4J5Z|rcsb pdb:4J60|rcsb pdb:4J61|rcsb pdb:4J62|rcsb pdb:4J63|rcsb pdb:4J64|rcsb pdb:4J65|rcsb pdb:4J66|rcsb pdb:3RH1|rcsb pdb:4J67|rcsb pdb:4J68|rcsb pdb:4J6A|rcsb pdb:4K7L|rcsb pdb:4K7M|rcsb pdb:4L55|rcsb pdb:4MXF|rcsb pdb:4O36|rcsb pdb:4O37|rcsb pdb:4OKF|rcsb pdb:4OOH|rcsb pdb:4OT4|rcsb pdb:4PEQ|rcsb pdb:4POU|rcsb pdb:4QH3|rcsb pdb:4RAT|rcsb pdb:4RSD|rcsb pdb:4RSK|rcsb pdb:4RTE|rcsb pdb:4S0Q|rcsb pdb:4S18|rcsb pdb:4SRN|rcsb pdb:4WYN|rcsb pdb:4WYP|rcsb pdb:4WYZ|rcsb pdb:4YGW|rcsb pdb:4ZZ4|rcsb pdb:5D6U|rcsb pdb:5D97|rcsb pdb:5E5E|rcsb pdb:5E5F|rcsb pdb:5ET4|rcsb pdb:5JLG|rcsb pdb:5JMG|rcsb pdb:4J69|rcsb pdb:5JML|rcsb pdb:5NA9|rcsb pdb:5NJ7|rcsb pdb:5OBD|rcsb pdb:5OBE|rcsb pdb:5OGH|rcsb pdb:5OLD|rcsb pdb:5RAT|rcsb pdb:5RSA|rcsb pdb:6ETK|rcsb pdb:6ETL|rcsb pdb:6ETM|rcsb pdb:6ETN|rcsb pdb:6ETO|rcsb pdb:6ETP|rcsb pdb:6ETQ|rcsb pdb:6ETR|rcsb pdb:6F60|rcsb pdb:6GOK|rcsb pdb:6PVU|rcsb pdb:6PVV|rcsb pdb:6PVW|rcsb pdb:6PVX|rcsb pdb:6QE9|rcsb pdb:6RAT|rcsb pdb:6RSA|rcsb pdb:6XHC|rcsb pdb:6XHD|rcsb pdb:6XHE|rcsb pdb:6XHF|rcsb pdb:6XVX|rcsb pdb:6XW0|rcsb pdb:6YO1|rcsb pdb:7RAT|rcsb pdb:7RSA|rcsb pdb:8RAT|rcsb pdb:8RSA|rcsb pdb:9RAT|rcsb pdb:9RSA|rcsb pdb:5OBC|ensembl:ENSBTAG00000008793(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004522"(ribonuclease A activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016829"(lyase activity)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|mint:P61823|rcsb pdb:1A2W|rcsb pdb:1A5P|rcsb pdb:1A5Q|rcsb pdb:1AFK|rcsb pdb:1AFL|rcsb pdb:1AFU|rcsb pdb:1AQP|rcsb pdb:1B6V|rcsb pdb:1BEL|rcsb pdb:1BZQ|rcsb pdb:1C0B|rcsb pdb:1C0C|rcsb pdb:1C8W|rcsb pdb:1C9V|rcsb pdb:1C9X|rcsb pdb:1CJQ|rcsb pdb:1CJR|rcsb pdb:1D5D|rcsb pdb:1D5E|rcsb pdb:1D5H|rcsb pdb:1DFJ|rcsb pdb:1DY5|rcsb pdb:1EIC|rcsb pdb:1EID|rcsb pdb:1EIE|rcsb pdb:1EOS|rcsb pdb:1EOW|rcsb pdb:1F0V|rcsb pdb:1FEV|ensembl:ENSBTAT00000011586(transcript)|rcsb pdb:1FS3|rcsb pdb:1GV7|rcsb pdb:1IZP|rcsb pdb:1IZQ|rcsb pdb:1IZR|rcsb pdb:1J7Z|rcsb pdb:1J80|rcsb pdb:1J81|rcsb pdb:1J82|rcsb pdb:1JN4|rcsb pdb:1JS0|rcsb pdb:1JVT|rcsb pdb:1JVU|rcsb pdb:1JVV|rcsb pdb:1KF2|rcsb pdb:1KF3|rcsb pdb:1KF4|rcsb pdb:1KF5|rcsb pdb:1KF7|rcsb pdb:1KF8|rcsb pdb:1KH8|rcsb pdb:1LSQ|rcsb pdb:1O0F|rcsb pdb:1O0H|rcsb pdb:1O0M|rcsb pdb:1O0N|rcsb pdb:1O0O|rcsb pdb:1QHC|rcsb pdb:1RAR|rcsb pdb:1RAS|rcsb pdb:1RAT|rcsb pdb:1RBB|rcsb pdb:1RBC|rcsb pdb:1RBD|rcsb pdb:1RBE|rcsb pdb:1RBF|rcsb pdb:1RBG|rcsb pdb:1RBH|rcsb pdb:1RBI|rcsb pdb:1RBJ|rcsb pdb:1RBN|rcsb pdb:1RBW|rcsb pdb:1RBX|rcsb pdb:1RCA|rcsb pdb:1RCN|rcsb pdb:1RHA|rcsb pdb:1RHB|rcsb pdb:1RNC|rcsb pdb:1RND|rcsb pdb:1RNM|rcsb pdb:1RNN|rcsb pdb:1RNO|rcsb pdb:1RNQ|rcsb pdb:1RNU|rcsb pdb:1RNV|rcsb pdb:1RNW|rcsb pdb:1RNX|rcsb pdb:1RNY|rcsb pdb:1RNZ|rcsb pdb:1ROB|rcsb pdb:1RPF|rcsb pdb:1RPG|rcsb pdb:1RPH|rcsb pdb:1RSM|rcsb pdb:1RTA|rcsb pdb:1RTB|rcsb pdb:1RUV|rcsb pdb:1SRN|rcsb pdb:1SSA|rcsb pdb:1SSB|rcsb pdb:1SSC|rcsb pdb:1U1B|rcsb pdb:1UN5|rcsb pdb:1W4O|rcsb pdb:1W4P|rcsb pdb:1W4Q|rcsb pdb:1WBU|rcsb pdb:1XPS|rcsb pdb:1XPT|rcsb pdb:1YMN|rcsb pdb:1YMR|rcsb pdb:1YMW|rcsb pdb:1Z3L|rcsb pdb:1Z3M|rcsb pdb:1Z3P|rcsb pdb:1Z6D|rcsb pdb:1Z6S|rcsb pdb:2AAS|rcsb pdb:2APQ|rcsb pdb:2APU|rcsb pdb:2BLP|rcsb pdb:2BLZ|rcsb pdb:2E33|rcsb pdb:2E3W|rcsb pdb:2G4W|rcsb pdb:2G4X|rcsb pdb:2G8Q|rcsb pdb:2G8R|rcsb pdb:2NUI|rcsb pdb:2OP2|rcsb pdb:2OQF|rcsb pdb:2P42|rcsb pdb:2P43|rcsb pdb:2P44|rcsb pdb:2P45|rcsb pdb:2P46|rcsb pdb:2P47|rcsb pdb:2P48|rcsb pdb:2P49|rcsb pdb:2P4A|rcsb pdb:2QCA|rcsb pdb:2RAT|rcsb pdb:2RLN|rcsb pdb:2RNS|rcsb pdb:2W5G|rcsb pdb:2W5I|rcsb pdb:2W5K|rcsb pdb:2W5L|rcsb pdb:2W5M|rcsb pdb:2XOG|rcsb pdb:2XOI|rcsb pdb:3A1R|rcsb pdb:3D6O|rcsb pdb:3D6P|rcsb pdb:3D6Q|rcsb pdb:3D7B|rcsb pdb:3D8Y|rcsb pdb:3D8Z|rcsb pdb:3DH5|rcsb pdb:3DH6|rcsb pdb:3DI7|rcsb pdb:3DI8|rcsb pdb:3DI9|rcsb pdb:3DIB|rcsb pdb:3DIC|rcsb pdb:3DXG|rcsb pdb:3DXH|rcsb pdb:3EUX|rcsb pdb:3EUY|rcsb pdb:3EUZ|rcsb pdb:3EV0|rcsb pdb:3EV1|rcsb pdb:3EV2|rcsb pdb:3EV3|rcsb pdb:3EV4|rcsb pdb:3EV5|rcsb pdb:3EV6|rcsb pdb:3FKZ|rcsb pdb:3FL0|rcsb pdb:3FL1|rcsb pdb:3FL3|rcsb pdb:3I67|rcsb pdb:3I6F|rcsb pdb:3I6H|rcsb pdb:3I6J|rcsb pdb:3I7W|rcsb pdb:3I7X|rcsb pdb:3I7Y|rcsb pdb:3JW1|rcsb pdb:3LXO|rcsb pdb:3MWQ|rcsb pdb:3MWR|rcsb pdb:3MX8|rcsb pdb:3MZQ|rcsb pdb:3MZR|rcsb pdb:3OQY|rcsb pdb:3OQZ|rcsb pdb:3OR0|rcsb pdb:3QL1|rcsb pdb:3QL2|rcsb pdb:3QSK|rcsb pdb:3RAT	-	-	-	kinetics:Ka=3.8E8 M-1secs-1, Tyr438phe mutation Kd=2.6E8M-1 secs-1, Tyr435phe mutation Kd=2.5E8M-1 secs-1|kinetic_conditions:pH=6.0, Temp=25C|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/10	2014/10/16	rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606	rogid:ifHI/UwVRIuj5ksIiZPB0pUY+0E9913	intact-crc:CC92316DFC90E59D|rigid:K+tloxjB9O3sGHEIqjWEHfb6a2I	false	mutation decreasing interaction:435-435|mutation decreasing interaction:438-438	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13489	uniprotkb:P03950	intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402|ensembl:ENSP00000348515|ensembl:ENSP00000380729|ensembl:ENSP00000380738|ensembl:ENSP00000380739|ensembl:ENSP00000416589|ensembl:ENSP00000433999|ensembl:ENSP00000435594|ensembl:ENSP00000478664|ensembl:ENSP00000479004|ensembl:ENSP00000479966|ensembl:ENSP00000480036|ensembl:ENSP00000484572|ensembl:ENSP00000487753|ensembl:ENSP00000487940|ensembl:ENSP00000488734	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym)	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	- (1999)	pubmed:10413501|pubmed:10413501|imex:IM-20526	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2944861|imex:IM-20526-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|refseq:XP_016873595.1|ensembl:ENST00000619599(transcript)|ensembl:ENST00000621211(transcript)|ensembl:ENST00000632527(transcript)|ensembl:ENST00000632954(transcript)|ensembl:ENST00000633287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|ensembl:ENSG00000023191(gene)|ensembl:ENSG00000276230(gene)|ensembl:ENST00000354420(transcript)|ensembl:ENST00000356187(transcript)|ensembl:ENST00000397604(transcript)|ensembl:ENST00000397614(transcript)|ensembl:ENST00000397615(transcript)|ensembl:ENST00000438658(transcript)|ensembl:ENST00000533410(transcript)|ensembl:ENST00000534797(transcript)|ensembl:ENST00000612988(transcript)|ensembl:ENST00000617351(transcript)|ensembl:ENST00000618184(transcript)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	-	-	-	kinetics:Kd=1E-7sec-1,  tyr435ala/asp436ala RNH1 Kd =2.7E-3sec-1, tyr435ala/tyr438ala kd=1.7E-3sec-1|kinetic_conditions:pH=6.0, Temp=25C|figure legend:Fig. 3, Table 2, Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/10	2014/10/16	rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	intact-crc:ED95E0C514B7FD41|rigid:RZ1qEz/b2CoFS4Z4Mufmwq3KAZw	false	mutation increasing interaction:435-436|mutation increasing interaction:438-438,435-435	14c radiolabel:?-?	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P61823	uniprotkb:P13489	intact:EBI-908364|uniprotkb:P00656|uniprotkb:Q9TSF2|uniprotkb:A6QPW8|ensembl:ENSBTAP00000011586	intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402|ensembl:ENSP00000348515|ensembl:ENSP00000380729|ensembl:ENSP00000380738|ensembl:ENSP00000380739|ensembl:ENSP00000416589|ensembl:ENSP00000433999|ensembl:ENSP00000435594|ensembl:ENSP00000478664|ensembl:ENSP00000479004|ensembl:ENSP00000479966|ensembl:ENSP00000480036|ensembl:ENSP00000484572|ensembl:ENSP00000487753|ensembl:ENSP00000487940|ensembl:ENSP00000488734	psi-mi:rnas1_bovin(display_long)|uniprotkb:RNASE1(gene name)|psi-mi:RNASE1(display_short)|uniprotkb:RNS1(gene name synonym)|uniprotkb:RNase 1(gene name synonym)|uniprotkb:RNase A(gene name synonym)	psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	- (1999)	pubmed:10413501|pubmed:10413501|imex:IM-20526	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2943956|imex:IM-20526-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001014408.2|refseq:XP_005211519.1|dip:DIP-36384N|rcsb pdb:3RID|rcsb pdb:3RN3|rcsb pdb:3RSD|rcsb pdb:3RSK|rcsb pdb:3RSP|rcsb pdb:3SRN|rcsb pdb:4AO1|rcsb pdb:4G8V|rcsb pdb:4G8Y|rcsb pdb:4G90|rcsb pdb:4J5Z|rcsb pdb:4J60|rcsb pdb:4J61|rcsb pdb:4J62|rcsb pdb:4J63|rcsb pdb:4J64|rcsb pdb:4J65|rcsb pdb:4J66|rcsb pdb:3RH1|rcsb pdb:4J67|rcsb pdb:4J68|rcsb pdb:4J6A|rcsb pdb:4K7L|rcsb pdb:4K7M|rcsb pdb:4L55|rcsb pdb:4MXF|rcsb pdb:4O36|rcsb pdb:4O37|rcsb pdb:4OKF|rcsb pdb:4OOH|rcsb pdb:4OT4|rcsb pdb:4PEQ|rcsb pdb:4POU|rcsb pdb:4QH3|rcsb pdb:4RAT|rcsb pdb:4RSD|rcsb pdb:4RSK|rcsb pdb:4RTE|rcsb pdb:4S0Q|rcsb pdb:4S18|rcsb pdb:4SRN|rcsb pdb:4WYN|rcsb pdb:4WYP|rcsb pdb:4WYZ|rcsb pdb:4YGW|rcsb pdb:4ZZ4|rcsb pdb:5D6U|rcsb pdb:5D97|rcsb pdb:5E5E|rcsb pdb:5E5F|rcsb pdb:5ET4|rcsb pdb:5JLG|rcsb pdb:5JMG|rcsb pdb:4J69|rcsb pdb:5JML|rcsb pdb:5NA9|rcsb pdb:5NJ7|rcsb pdb:5OBD|rcsb pdb:5OBE|rcsb pdb:5OGH|rcsb pdb:5OLD|rcsb pdb:5RAT|rcsb pdb:5RSA|rcsb pdb:6ETK|rcsb pdb:6ETL|rcsb pdb:6ETM|rcsb pdb:6ETN|rcsb pdb:6ETO|rcsb pdb:6ETP|rcsb pdb:6ETQ|rcsb pdb:6ETR|rcsb pdb:6F60|rcsb pdb:6GOK|rcsb pdb:6PVU|rcsb pdb:6PVV|rcsb pdb:6PVW|rcsb pdb:6PVX|rcsb pdb:6QE9|rcsb pdb:6RAT|rcsb pdb:6RSA|rcsb pdb:6XHC|rcsb pdb:6XHD|rcsb pdb:6XHE|rcsb pdb:6XHF|rcsb pdb:6XVX|rcsb pdb:6XW0|rcsb pdb:6YO1|rcsb pdb:7RAT|rcsb pdb:7RSA|rcsb pdb:8RAT|rcsb pdb:8RSA|rcsb pdb:9RAT|rcsb pdb:9RSA|rcsb pdb:5OBC|ensembl:ENSBTAG00000008793(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004522"(ribonuclease A activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016829"(lyase activity)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|mint:P61823|rcsb pdb:1A2W|rcsb pdb:1A5P|rcsb pdb:1A5Q|rcsb pdb:1AFK|rcsb pdb:1AFL|rcsb pdb:1AFU|rcsb pdb:1AQP|rcsb pdb:1B6V|rcsb pdb:1BEL|rcsb pdb:1BZQ|rcsb pdb:1C0B|rcsb pdb:1C0C|rcsb pdb:1C8W|rcsb pdb:1C9V|rcsb pdb:1C9X|rcsb pdb:1CJQ|rcsb pdb:1CJR|rcsb pdb:1D5D|rcsb pdb:1D5E|rcsb pdb:1D5H|rcsb pdb:1DFJ|rcsb pdb:1DY5|rcsb pdb:1EIC|rcsb pdb:1EID|rcsb pdb:1EIE|rcsb pdb:1EOS|rcsb pdb:1EOW|rcsb pdb:1F0V|rcsb pdb:1FEV|ensembl:ENSBTAT00000011586(transcript)|rcsb pdb:1FS3|rcsb pdb:1GV7|rcsb pdb:1IZP|rcsb pdb:1IZQ|rcsb pdb:1IZR|rcsb pdb:1J7Z|rcsb pdb:1J80|rcsb pdb:1J81|rcsb pdb:1J82|rcsb pdb:1JN4|rcsb pdb:1JS0|rcsb pdb:1JVT|rcsb pdb:1JVU|rcsb pdb:1JVV|rcsb pdb:1KF2|rcsb pdb:1KF3|rcsb pdb:1KF4|rcsb pdb:1KF5|rcsb pdb:1KF7|rcsb pdb:1KF8|rcsb pdb:1KH8|rcsb pdb:1LSQ|rcsb pdb:1O0F|rcsb pdb:1O0H|rcsb pdb:1O0M|rcsb pdb:1O0N|rcsb pdb:1O0O|rcsb pdb:1QHC|rcsb pdb:1RAR|rcsb pdb:1RAS|rcsb pdb:1RAT|rcsb pdb:1RBB|rcsb pdb:1RBC|rcsb pdb:1RBD|rcsb pdb:1RBE|rcsb pdb:1RBF|rcsb pdb:1RBG|rcsb pdb:1RBH|rcsb pdb:1RBI|rcsb pdb:1RBJ|rcsb pdb:1RBN|rcsb pdb:1RBW|rcsb pdb:1RBX|rcsb pdb:1RCA|rcsb pdb:1RCN|rcsb pdb:1RHA|rcsb pdb:1RHB|rcsb pdb:1RNC|rcsb pdb:1RND|rcsb pdb:1RNM|rcsb pdb:1RNN|rcsb pdb:1RNO|rcsb pdb:1RNQ|rcsb pdb:1RNU|rcsb pdb:1RNV|rcsb pdb:1RNW|rcsb pdb:1RNX|rcsb pdb:1RNY|rcsb pdb:1RNZ|rcsb pdb:1ROB|rcsb pdb:1RPF|rcsb pdb:1RPG|rcsb pdb:1RPH|rcsb pdb:1RSM|rcsb pdb:1RTA|rcsb pdb:1RTB|rcsb pdb:1RUV|rcsb pdb:1SRN|rcsb pdb:1SSA|rcsb pdb:1SSB|rcsb pdb:1SSC|rcsb pdb:1U1B|rcsb pdb:1UN5|rcsb pdb:1W4O|rcsb pdb:1W4P|rcsb pdb:1W4Q|rcsb pdb:1WBU|rcsb pdb:1XPS|rcsb pdb:1XPT|rcsb pdb:1YMN|rcsb pdb:1YMR|rcsb pdb:1YMW|rcsb pdb:1Z3L|rcsb pdb:1Z3M|rcsb pdb:1Z3P|rcsb pdb:1Z6D|rcsb pdb:1Z6S|rcsb pdb:2AAS|rcsb pdb:2APQ|rcsb pdb:2APU|rcsb pdb:2BLP|rcsb pdb:2BLZ|rcsb pdb:2E33|rcsb pdb:2E3W|rcsb pdb:2G4W|rcsb pdb:2G4X|rcsb pdb:2G8Q|rcsb pdb:2G8R|rcsb pdb:2NUI|rcsb pdb:2OP2|rcsb pdb:2OQF|rcsb pdb:2P42|rcsb pdb:2P43|rcsb pdb:2P44|rcsb pdb:2P45|rcsb pdb:2P46|rcsb pdb:2P47|rcsb pdb:2P48|rcsb pdb:2P49|rcsb pdb:2P4A|rcsb pdb:2QCA|rcsb pdb:2RAT|rcsb pdb:2RLN|rcsb pdb:2RNS|rcsb pdb:2W5G|rcsb pdb:2W5I|rcsb pdb:2W5K|rcsb pdb:2W5L|rcsb pdb:2W5M|rcsb pdb:2XOG|rcsb pdb:2XOI|rcsb pdb:3A1R|rcsb pdb:3D6O|rcsb pdb:3D6P|rcsb pdb:3D6Q|rcsb pdb:3D7B|rcsb pdb:3D8Y|rcsb pdb:3D8Z|rcsb pdb:3DH5|rcsb pdb:3DH6|rcsb pdb:3DI7|rcsb pdb:3DI8|rcsb pdb:3DI9|rcsb pdb:3DIB|rcsb pdb:3DIC|rcsb pdb:3DXG|rcsb pdb:3DXH|rcsb pdb:3EUX|rcsb pdb:3EUY|rcsb pdb:3EUZ|rcsb pdb:3EV0|rcsb pdb:3EV1|rcsb pdb:3EV2|rcsb pdb:3EV3|rcsb pdb:3EV4|rcsb pdb:3EV5|rcsb pdb:3EV6|rcsb pdb:3FKZ|rcsb pdb:3FL0|rcsb pdb:3FL1|rcsb pdb:3FL3|rcsb pdb:3I67|rcsb pdb:3I6F|rcsb pdb:3I6H|rcsb pdb:3I6J|rcsb pdb:3I7W|rcsb pdb:3I7X|rcsb pdb:3I7Y|rcsb pdb:3JW1|rcsb pdb:3LXO|rcsb pdb:3MWQ|rcsb pdb:3MWR|rcsb pdb:3MX8|rcsb pdb:3MZQ|rcsb pdb:3MZR|rcsb pdb:3OQY|rcsb pdb:3OQZ|rcsb pdb:3OR0|rcsb pdb:3QL1|rcsb pdb:3QL2|rcsb pdb:3QSK|rcsb pdb:3RAT	refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|refseq:XP_016873595.1|ensembl:ENST00000619599(transcript)|ensembl:ENST00000621211(transcript)|ensembl:ENST00000632527(transcript)|ensembl:ENST00000632954(transcript)|ensembl:ENST00000633287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|ensembl:ENSG00000023191(gene)|ensembl:ENSG00000276230(gene)|ensembl:ENST00000354420(transcript)|ensembl:ENST00000356187(transcript)|ensembl:ENST00000397604(transcript)|ensembl:ENST00000397614(transcript)|ensembl:ENST00000397615(transcript)|ensembl:ENST00000438658(transcript)|ensembl:ENST00000533410(transcript)|ensembl:ENST00000534797(transcript)|ensembl:ENST00000612988(transcript)|ensembl:ENST00000617351(transcript)|ensembl:ENST00000618184(transcript)	-	-	-	kinetics:Kd=1.2E-5 secs-1, Tyr438phe mutantion Kd=2.9E-4M|kinetic_conditions:pH=6.0, Temp=25C|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/10	2014/10/16	rogid:ifHI/UwVRIuj5ksIiZPB0pUY+0E9913	rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606	intact-crc:F5D517438969574F|rigid:K+tloxjB9O3sGHEIqjWEHfb6a2I	false	-	mutation decreasing interaction:438-438	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)