#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P04821	uniprotkb:P08678	intact:EBI-4237|uniprotkb:D6VYV4|ensemblfungi:YLR310C	intact:EBI-5364|uniprotkb:D6VWH0|ensemblfungi:YJL005W	psi-mi:cdc25_yeast(display_long)|uniprotkb:CDC25(gene name)|psi-mi:CDC25(display_short)|uniprotkb:CTN1(gene name synonym)|uniprotkb:YLR310C(locus name)|uniprotkb:L2142.6(orf name)	psi-mi:cyaa_yeast(display_long)|uniprotkb:CYR1(gene name)|psi-mi:CYR1(display_short)|uniprotkb:CDC35(gene name synonym)|uniprotkb:HSR1(gene name synonym)|uniprotkb:SRA4(gene name synonym)|uniprotkb:YJL005W(locus name)|uniprotkb:J1401(orf name)|uniprotkb:Adenylyl cyclase(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Mintzer et al. (1999)	pubmed:10048790|mint:MINT-5211185	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6945261|mint:MINT-7721138	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013413.1|sgd:S000004301|dip:DIP-2261N|mint:P04821|ensemblfungi:YLR310C(gene)|ensemblfungi:YLR310C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR019804|interpro:IPR023578|interpro:IPR036028|interpro:IPR036964|reactome:R-SCE-354192|reactome:R-SCE-392517|reactome:R-SCE-416482|mint:MINT-7721139(identity)|uniprotkb:P04821(original identifier)	sgd:S000003542|refseq:NP_012529.3|dip:DIP-2317N|mint:P08678|ensemblfungi:YJL005W(gene)|ensemblfungi:YJL005W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016791"(phosphatase activity)|interpro:IPR000159(Ras-association)|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013716(Adenylate cyclase G-alpha binding)|interpro:IPR029787|interpro:IPR032675|interpro:IPR036457|reactome:R-SCE-199418|reactome:R-SCE-5223345|mint:MINT-7721145(identity)|uniprotkb:P08678(original identifier)	-	crc64:CA90053435C85465	crc64:BEAB7419AB6989D0	figure legend:F3|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2010/04/07	2014/10/16	rogid:odGMmVuh+nvSK5Z37n++BP0jW5E559292	rogid:jcjdcDnCxKuonhXVJ9cUa6cAiwA559292	intact-crc:09B8DE9EF7D0EC8D|rigid:cym6+DnLNctVxtA5l1X4m0ZZFCk	false	binding-associated region:61-127(MINT-7721142)	binding-associated region:1769-1960(MINT-7721148)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)