#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9VEX9 uniprotkb:P60953 intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506 intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|uniprotkb:Q9UDI2|ensembl:ENSP00000341072|ensembl:ENSP00000383118|ensembl:ENSP00000497733|ensembl:ENSP00000499457|ensembl:ENSP00000499612 psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym) psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Evangelista et al. (1997) pubmed:9082982|imex:IM-20287 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2299424|imex:IM-20287-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007097"(nuclear migration)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016020"(membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030141"(secretory granule)|go:"GO:0030175"(filopodium)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030496"(midbody)|go:"GO:0005886"(plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0005911"(cell-cell junction)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0038189"(neuropilin signaling pathway)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0031996"(thioesterase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0032427"(GBD domain binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|ensembl:ENSG00000070831(gene)|ensembl:ENST00000344548(transcript)|ensembl:ENST00000400259(transcript)|ensembl:ENST00000648594(transcript)|ensembl:ENST00000656825(transcript)|ensembl:ENST00000662562(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000322"(storage vacuole)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0060661"(submandibular salivary gland formation)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072384"(organelle transport along microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090135"(actin filament branching)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|go:"GO:0046847"(filopodium assembly)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0048664"(neuron fate determination)|go:"GO:0051233"(spindle midzone)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0060047"(heart contraction)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|dip:DIP-31097N|reactome:R-HSA-983231|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1AN0|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|rcsb pdb:1A4R|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422 - - - figure legend:table 1, fig 2|complex-synonym:"Two-hybrid tests of protein-protein interactions demonstrated that Cdc42p can associate with Bni1p; the interaction was localized to amino acids 1 to 1214 of Bni1p (Table 1). The interaction of Cdc42p with Bni1p was specific for the activated form of Cdc42p: Cdc42pG12V"|comment:G12V is a constitutively GTP bound form of the protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/04/01 2014/10/16 rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227 rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606 intact-crc:EA720FA53892D4FF|rigid:NCVTfgkYxJOLWE3qdKKbgaeeet8 false sufficient binding region:?-? mutation disrupting interaction:118-118|mutation increasing interaction:12-12 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07274 uniprotkb:P60010 intact:EBI-13892|uniprotkb:D6W2I0|ensemblfungi:YOR122C intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C psi-mi:prof_yeast(display_long)|uniprotkb:PFY1(gene name)|psi-mi:PFY1(display_short)|uniprotkb:PFY(gene name synonym)|uniprotkb:PRF1(gene name synonym)|uniprotkb:YOR122C(locus name)|uniprotkb:O3275(orf name)|uniprotkb:YOR3275C(orf name) psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name) psi-mi:"MI:0018"(two hybrid) Evangelista et al. (1997) pubmed:9082982|imex:IM-20287 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2300130|imex:IM-20287-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR122C(gene)|ensemblfungi:YOR122C_mRNA(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005938"(cell cortex)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0046907"(intracellular transport)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0090338"(positive regulation of formin-nucleated actin cable assembly)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR036140|rcsb pdb:1K0K|rcsb pdb:1YPR|sgd:S000005648|refseq:NP_014765.3|mint:P07274|dip:DIP-46N refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026 - crc64:2485E413AB30DEAD crc64:87AC19B0B0BC9E71 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/04/01 2014/10/16 rogid:L2EmA4vaI8ilSAvf8c2smlCYWUo559292 rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292 intact-crc:79D63ABFDC4AB071|rigid:RSq5PWSqQQjxPqOA968YheU82dU false sufficient binding region:1-123 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07274 uniprotkb:Q9VEX9 intact:EBI-13892|uniprotkb:D6W2I0|ensemblfungi:YOR122C intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506 psi-mi:prof_yeast(display_long)|uniprotkb:PFY1(gene name)|psi-mi:PFY1(display_short)|uniprotkb:PFY(gene name synonym)|uniprotkb:PRF1(gene name synonym)|uniprotkb:YOR122C(locus name)|uniprotkb:O3275(orf name)|uniprotkb:YOR3275C(orf name) psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym) psi-mi:"MI:0018"(two hybrid) Evangelista et al. (1997) pubmed:9082982|imex:IM-20287 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2300148|imex:IM-20287-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR122C(gene)|ensemblfungi:YOR122C_mRNA(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005938"(cell cortex)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0046907"(intracellular transport)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0090338"(positive regulation of formin-nucleated actin cable assembly)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR036140|rcsb pdb:1K0K|rcsb pdb:1YPR|sgd:S000005648|refseq:NP_014765.3|mint:P07274|dip:DIP-46N refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N - crc64:2485E413AB30DEAD - figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/04/01 2014/10/16 rogid:L2EmA4vaI8ilSAvf8c2smlCYWUo559292 rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227 intact-crc:ACDE727660A81010|rigid:iDekuYo+4Dwy2huNn6+bQns1qPs false - sufficient binding region:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9VEX9 uniprotkb:P07274 intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506 intact:EBI-13892|uniprotkb:D6W2I0|ensemblfungi:YOR122C psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym) psi-mi:prof_yeast(display_long)|uniprotkb:PFY1(gene name)|psi-mi:PFY1(display_short)|uniprotkb:PFY(gene name synonym)|uniprotkb:PRF1(gene name synonym)|uniprotkb:YOR122C(locus name)|uniprotkb:O3275(orf name)|uniprotkb:YOR3275C(orf name) psi-mi:"MI:0018"(two hybrid) Evangelista et al. (1997) pubmed:9082982|imex:IM-20287 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2300182|imex:IM-20287-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N ensemblfungi:YOR122C(gene)|ensemblfungi:YOR122C_mRNA(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005938"(cell cortex)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0046907"(intracellular transport)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0090338"(positive regulation of formin-nucleated actin cable assembly)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR036140|rcsb pdb:1K0K|rcsb pdb:1YPR|sgd:S000005648|refseq:NP_014765.3|mint:P07274|dip:DIP-46N - - crc64:2485E413AB30DEAD figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/04/01 2014/10/16 rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227 rogid:L2EmA4vaI8ilSAvf8c2smlCYWUo559292 intact-crc:34E12D5FFCF65715|rigid:iDekuYo+4Dwy2huNn6+bQns1qPs false sufficient binding region:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9VEX9 uniprotkb:P41697 intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506 intact:EBI-3857|uniprotkb:D6VYW2|ensemblfungi:YLR319C psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym) psi-mi:bud6_yeast(display_long)|uniprotkb:BUD6(gene name)|psi-mi:BUD6(display_short)|uniprotkb:Actin-interacting protein 3(gene name synonym)|uniprotkb:AIP3(gene name synonym)|uniprotkb:L8543.5(orf name)|uniprotkb:YLR319C(locus name) psi-mi:"MI:0018"(two hybrid) Evangelista et al. (1997) pubmed:9082982|imex:IM-20287 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2300500|imex:IM-20287-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N refseq:NP_013423.1|sgd:S000004311|dip:DIP-880N|mint:P41697|ensemblfungi:YLR319C(gene)|ensemblfungi:YLR319C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000133"(polarisome)|go:"GO:0003779"(actin binding)|go:"GO:0005519"(cytoskeletal regulatory protein binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034652"(extrachromosomal circular DNA localization involved in cell aging)|go:"GO:0043332"(mating projection tip)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051286"(cell tip)|go:"GO:0090338"(positive regulation of formin-nucleated actin cable assembly)|go:"GO:0099503"(secretory vesicle)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR005613(Actin interacting protein 3)|interpro:IPR022782|rcsb pdb:3OKQ|rcsb pdb:3ONX|rcsb pdb:4WYB - - crc64:4BAE8F541B8BDF1F figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/04/01 2014/10/16 rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227 rogid:eyN8DMoUVDSGMzkV901bJJgSt4M559292 intact-crc:EF196ED3A2CD9B53|rigid:fl7CLc0rhLmeTCEbS867K8sp5C0 false sufficient binding region:?-? protein a tag:478-788 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9VEX9 uniprotkb:P60010 intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506 intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym) psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name) psi-mi:"MI:0018"(two hybrid) Evangelista et al. (1997) pubmed:9082982|imex:IM-20287 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2300570|imex:IM-20287-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026 - - crc64:87AC19B0B0BC9E71 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/04/01 2014/10/16 rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227 rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292 intact-crc:6D79DC64889DA834|rigid:eO6wCikxdo72MxLZit6x86dpU/g false sufficient binding region:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9VEX9 uniprotkb:P07274 intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506 intact:EBI-13892|uniprotkb:D6W2I0|ensemblfungi:YOR122C psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym) psi-mi:prof_yeast(display_long)|uniprotkb:PFY1(gene name)|psi-mi:PFY1(display_short)|uniprotkb:PFY(gene name synonym)|uniprotkb:PRF1(gene name synonym)|uniprotkb:YOR122C(locus name)|uniprotkb:O3275(orf name)|uniprotkb:YOR3275C(orf name) psi-mi:"MI:0096"(pull down) Evangelista et al. (1997) pubmed:9082982|imex:IM-20287 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2299447|imex:IM-20287-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N ensemblfungi:YOR122C(gene)|ensemblfungi:YOR122C_mRNA(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005938"(cell cortex)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0046907"(intracellular transport)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0090338"(positive regulation of formin-nucleated actin cable assembly)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR036140|rcsb pdb:1K0K|rcsb pdb:1YPR|sgd:S000005648|refseq:NP_014765.3|mint:P07274|dip:DIP-46N - - crc64:2485E413AB30DEAD figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/04/01 2014/10/16 rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227 rogid:L2EmA4vaI8ilSAvf8c2smlCYWUo559292 intact-crc:B1108F4C5400CF70|rigid:iDekuYo+4Dwy2huNn6+bQns1qPs false ha tag:?-?|sufficient binding region:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P60953 uniprotkb:Q9VEX9 intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|uniprotkb:Q9UDI2|ensembl:ENSP00000341072|ensembl:ENSP00000383118|ensembl:ENSP00000497733|ensembl:ENSP00000499457|ensembl:ENSP00000499612 intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506 psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym) psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym) psi-mi:"MI:0096"(pull down) Evangelista et al. (1997) pubmed:9082982|imex:IM-20287 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2299458|imex:IM-20287-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007097"(nuclear migration)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016020"(membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030141"(secretory granule)|go:"GO:0030175"(filopodium)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030496"(midbody)|go:"GO:0005886"(plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0005911"(cell-cell junction)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0038189"(neuropilin signaling pathway)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0031996"(thioesterase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0032427"(GBD domain binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|ensembl:ENSG00000070831(gene)|ensembl:ENST00000344548(transcript)|ensembl:ENST00000400259(transcript)|ensembl:ENST00000648594(transcript)|ensembl:ENST00000656825(transcript)|ensembl:ENST00000662562(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000322"(storage vacuole)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0060661"(submandibular salivary gland formation)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072384"(organelle transport along microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090135"(actin filament branching)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|go:"GO:0046847"(filopodium assembly)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0048664"(neuron fate determination)|go:"GO:0051233"(spindle midzone)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0060047"(heart contraction)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|dip:DIP-31097N|reactome:R-HSA-983231|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1AN0|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|rcsb pdb:1A4R|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422 refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N - - - figure legend:2A|comment:GTPgamma S-bound Cdc42 associated with Bni1, but GDP-bound Cdc42 or nucleotide-free Cdc42 did not.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/04/01 2014/10/16 rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606 rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227 intact-crc:14C88305DB084CDA|rigid:NCVTfgkYxJOLWE3qdKKbgaeeet8 false his tag:?-? ha tag:?-?|sufficient binding region:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)