#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P21457	uniprotkb:P28327	intact:EBI-8592784|ensembl:ENSBTAP00000034949|intact:MINT-1507490	intact:EBI-7865560|intact:MINT-1507451|ensembl:ENSBTAP00000042484	psi-mi:reco_bovin(display_long)|uniprotkb:RCVRN(gene name)|psi-mi:RCVRN(display_short)|uniprotkb:RCV1(gene name synonym)|uniprotkb:p26(gene name synonym)	psi-mi:grk1_bovin(display_long)|uniprotkb:GRK1(gene name)|psi-mi:GRK1(display_short)|uniprotkb:RHOK(gene name synonym)|uniprotkb:G protein-coupled receptor kinase 1(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Chen et al. (1995)	pubmed:7629115|mint:MINT-6825222|doi:10.1074/jbc.270.30.18060	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8592780|mint:MINT-6825229	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR018247|interpro:IPR028846|mint:P21457|rcsb pdb:1IKU|rcsb pdb:1JSA|rcsb pdb:1LA3|rcsb pdb:1OMR|rcsb pdb:1OMV|rcsb pdb:1REC|rcsb pdb:2HET|ensembl:ENSBTAG00000025088(gene)|ensembl:ENSBTAT00000035069(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0016020"(membrane)|go:"GO:0043204"(perikaryon)|go:"GO:0051924"(regulation of calcium ion transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:2I94|rcsb pdb:4M2O|rcsb pdb:4M2Q|rcsb pdb:4MLW|rcsb pdb:4YI8|rcsb pdb:4YI9|rcsb pdb:4M2P|refseq:NP_776590.1|mint:MINT-6825233(identity)|uniprotkb:P21457(P21457)	go:"GO:0007601"(visual perception)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032965|interpro:IPR036305|interpro:IPR037716|mint:P28327|rcsb pdb:2I94|rcsb pdb:3C4W|rcsb pdb:3C4X|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:3C4Y|rcsb pdb:3C4Z|rcsb pdb:3C50|rcsb pdb:3C51|rcsb pdb:3QC9|rcsb pdb:3T8O|rcsb pdb:4L9I|rcsb pdb:4PNI|rcsb pdb:4WBO|go:"GO:0050254"(rhodopsin kinase activity)|go:"GO:0097381"(photoreceptor disc membrane)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|refseq:NP_776598.1|ensembl:ENSBTAG00000019963(gene)|ensembl:ENSBTAT00000045068(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|mint:MINT-6825230(identity)|uniprotkb:P28327(P28327)	-	comment:mint|function:Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse	comment:mint|function:Phosphorylates rhodopsin thereby initiating its deactivation	figure legend:F2A|comment:mint	taxid:9913(bovin-retina)|taxid:9913(Bovine retina)	-	2009/01/23	2014/10/16	rogid:EPz6+aiLYRgBW2NlAy6p7LND5hI9913	rogid:eM0swfTKn7hxl0UaF0fUxQW6DuI9913	intact-crc:3515E75388926431|rigid:yY0XaR/CLk/HJNu/1vkJ/3gkiOo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P28327	uniprotkb:P02699	intact:EBI-7865560|intact:MINT-1507451|ensembl:ENSBTAP00000042484	intact:EBI-8592832|ensembl:ENSBTAP00000001730|intact:MINT-1507462	psi-mi:grk1_bovin(display_long)|uniprotkb:GRK1(gene name)|psi-mi:GRK1(display_short)|uniprotkb:RHOK(gene name synonym)|uniprotkb:G protein-coupled receptor kinase 1(gene name synonym)	psi-mi:opsd_bovin(display_long)|uniprotkb:RHO(gene name)|psi-mi:RHO(display_short)	psi-mi:"MI:0424"(protein kinase assay)	Chen et al. (1995)	pubmed:7629115|mint:MINT-6825222|doi:10.1074/jbc.270.30.18060	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8592828|mint:MINT-6825238	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007601"(visual perception)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032965|interpro:IPR036305|interpro:IPR037716|mint:P28327|rcsb pdb:2I94|rcsb pdb:3C4W|rcsb pdb:3C4X|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:3C4Y|rcsb pdb:3C4Z|rcsb pdb:3C50|rcsb pdb:3C51|rcsb pdb:3QC9|rcsb pdb:3T8O|rcsb pdb:4L9I|rcsb pdb:4PNI|rcsb pdb:4WBO|go:"GO:0050254"(rhodopsin kinase activity)|go:"GO:0097381"(photoreceptor disc membrane)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|refseq:NP_776598.1|ensembl:ENSBTAG00000019963(gene)|ensembl:ENSBTAT00000045068(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|mint:MINT-6825242(identity)|uniprotkb:P28327(P28327)	ensembl:ENSBTAG00000001310(gene)|ensembl:ENSBTAT00000001730(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0002046"(opsin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005502"(11-cis retinal binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016038"(absorption of visible light)|go:"GO:0016056"(rhodopsin mediated signaling pathway)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019867"(outer membrane)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043052"(thermotaxis)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097381"(photoreceptor disc membrane)|go:"GO:0097648"(G protein-coupled receptor complex)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:1990913"(sperm head plasma membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000732(Rhodopsin)|interpro:IPR001760(Opsin)|rcsb pdb:1NZS|rcsb pdb:1OV0|rcsb pdb:1OV1|rcsb pdb:1U19|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:1VQX|rcsb pdb:2G87|rcsb pdb:2HPY|interpro:IPR019477|rcsb pdb:2I35|interpro:IPR027430|mint:P02699|rcsb pdb:1BOJ|rcsb pdb:1BOK|rcsb pdb:1EDS|rcsb pdb:1EDV|rcsb pdb:1EDW|rcsb pdb:2I36|rcsb pdb:2I37|rcsb pdb:2IQK|rcsb pdb:2J4Y|rcsb pdb:1EDX|rcsb pdb:2PED|rcsb pdb:2X72|rcsb pdb:3C9L|rcsb pdb:3C9M|rcsb pdb:3CAP|rcsb pdb:3DQB|rcsb pdb:3OAX|rcsb pdb:3PQR|rcsb pdb:3PXO|rcsb pdb:4A4M|rcsb pdb:4BEY|rcsb pdb:1F88|rcsb pdb:4BEZ|rcsb pdb:1FDF|rcsb pdb:1GZM|rcsb pdb:4J4Q|rcsb pdb:4PXF|rcsb pdb:4X1H|rcsb pdb:5DYS|rcsb pdb:5EN0|rcsb pdb:5TE3|rcsb pdb:5TE5|rcsb pdb:5WKT|rcsb pdb:6FK6|rcsb pdb:6FK7|rcsb pdb:6FK8|rcsb pdb:6FK9|rcsb pdb:6FKA|rcsb pdb:6FKB|rcsb pdb:6FKC|rcsb pdb:6FKD|rcsb pdb:6FUF|rcsb pdb:6NWE|rcsb pdb:6OFJ|rcsb pdb:6OY9|rcsb pdb:6OYA|rcsb pdb:6PEL|rcsb pdb:6PGS|rcsb pdb:6PH7|rcsb pdb:6QNO|reactome:R-BTA-2453902|reactome:R-BTA-2485179|reactome:R-BTA-2514859|reactome:R-BTA-418594|reactome:R-BTA-419771|reactome:R-BTA-5620916|rcsb pdb:1HZX|rcsb pdb:1JFP|rcsb pdb:1L9H|rcsb pdb:1LN6|rcsb pdb:1N3M|refseq:NP_001014890.1|dip:DIP-29225N|mint:MINT-6825239(identity)|uniprotkb:P02699(P02699)	-	comment:mint|function:Phosphorylates rhodopsin thereby initiating its deactivation	comment:mint|function:Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal	figure legend:F3 F4 F5|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/23	2014/10/16	rogid:eM0swfTKn7hxl0UaF0fUxQW6DuI9913	rogid:ntvPNbJU0fcn+gajwUZzvfd/YCI9913	intact-crc:AE1035EC3125BD74|rigid:BDqaaRZNbRwLpivQUc/B613fyvw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21457	uniprotkb:P81948	intact:EBI-8592784|ensembl:ENSBTAP00000034949|intact:MINT-1507490	intact:EBI-6943159|ensembl:ENSBTAP00000065307|uniprotkb:Q17QT1|intact:MINT-3387904|uniprotkb:Q5E986	psi-mi:reco_bovin(display_long)|uniprotkb:RCVRN(gene name)|psi-mi:RCVRN(display_short)|uniprotkb:RCV1(gene name synonym)|uniprotkb:p26(gene name synonym)	psi-mi:tba4a_bovin(display_long)|uniprotkb:TUBA1(gene name synonym)|uniprotkb:TUBA4A(gene name)|psi-mi:TUBA4A(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chen et al. (1995)	pubmed:7629115|mint:MINT-6825222|doi:10.1074/jbc.270.30.18060	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8592936|mint:MINT-6825247	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR018247|interpro:IPR028846|mint:P21457|rcsb pdb:1IKU|rcsb pdb:1JSA|rcsb pdb:1LA3|rcsb pdb:1OMR|rcsb pdb:1OMV|rcsb pdb:1REC|rcsb pdb:2HET|ensembl:ENSBTAG00000025088(gene)|ensembl:ENSBTAT00000035069(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0016020"(membrane)|go:"GO:0043204"(perikaryon)|go:"GO:0051924"(regulation of calcium ion transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:2I94|rcsb pdb:4M2O|rcsb pdb:4M2Q|rcsb pdb:4MLW|rcsb pdb:4YI8|rcsb pdb:4YI9|rcsb pdb:4M2P|refseq:NP_776590.1|mint:MINT-6825248(identity)|uniprotkb:P21457(P21457)	ensembl:ENSBTAG00000030974(gene)|ensembl:ENSBTAT00000085322(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P81948|refseq:NP_001071626.1|mint:MINT-6825257(identity)|uniprotkb:P81948(P81948)	-	comment:mint|function:Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse	comment:mint|function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain	figure legend:F1A|comment:homomint|comment:mint	taxid:9913(bovin-retina)|taxid:9913(Bovine retina)	-	2009/01/23	2014/10/16	rogid:EPz6+aiLYRgBW2NlAy6p7LND5hI9913	rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ9913	intact-crc:E26C90BE45E179F8|rigid:7wR3MQyQOeqY02OWgv83+/jbsjg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P21457	uniprotkb:P12661	intact:EBI-8592784|ensembl:ENSBTAP00000034949|intact:MINT-1507490	intact:EBI-8592916|intact:MINT-6824777	psi-mi:reco_bovin(display_long)|uniprotkb:RCVRN(gene name)|psi-mi:RCVRN(display_short)|uniprotkb:RCV1(gene name synonym)|uniprotkb:p26(gene name synonym)	psi-mi:ret3_bovin(display_long)|uniprotkb:Protein 7S(gene name synonym)|uniprotkb:RBP3(gene name)|psi-mi:RBP3(display_short)|uniprotkb:Interphotoreceptor retinoid-binding protein(gene name synonym)|uniprotkb:Interstitial retinol-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chen et al. (1995)	pubmed:7629115|mint:MINT-6825222|doi:10.1074/jbc.270.30.18060	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8592936|mint:MINT-6825247	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR018247|interpro:IPR028846|mint:P21457|rcsb pdb:1IKU|rcsb pdb:1JSA|rcsb pdb:1LA3|rcsb pdb:1OMR|rcsb pdb:1OMV|rcsb pdb:1REC|rcsb pdb:2HET|ensembl:ENSBTAG00000025088(gene)|ensembl:ENSBTAT00000035069(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0016020"(membrane)|go:"GO:0043204"(perikaryon)|go:"GO:0051924"(regulation of calcium ion transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:2I94|rcsb pdb:4M2O|rcsb pdb:4M2Q|rcsb pdb:4MLW|rcsb pdb:4YI8|rcsb pdb:4YI9|rcsb pdb:4M2P|refseq:NP_776590.1|mint:MINT-6825248(identity)|uniprotkb:P21457(P21457)	go:"GO:0005576"(extracellular region)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016918"(retinal binding)|go:"GO:0019841"(retinol binding)|go:"GO:0090658"(cone matrix sheath)|interpro:IPR029045|refseq:NP_776589.1|interpro:IPR005151(Peptidase S41)|mint:P12661|mint:MINT-6825254(identity)|uniprotkb:P12661(P12661)	-	comment:mint|function:Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse	function:IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina|comment:mint	figure legend:F1A|comment:homomint|comment:mint	taxid:9913(bovin-retina)|taxid:9913(Bovine retina)	-	2009/01/23	2014/10/16	rogid:EPz6+aiLYRgBW2NlAy6p7LND5hI9913	rogid:p7RMPfLisIbQ2L0jw+MYTv0itlw9913	intact-crc:E26C90BE45E179F8|rigid:7wR3MQyQOeqY02OWgv83+/jbsjg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P21457	uniprotkb:Q6B856	intact:EBI-8592784|ensembl:ENSBTAP00000034949|intact:MINT-1507490	intact:EBI-7634703|intact:MINT-6604256	psi-mi:reco_bovin(display_long)|uniprotkb:RCVRN(gene name)|psi-mi:RCVRN(display_short)|uniprotkb:RCV1(gene name synonym)|uniprotkb:p26(gene name synonym)	psi-mi:tbb2b_bovin(display_long)|uniprotkb:TUBB2B(gene name)|psi-mi:TUBB2B(display_short)	psi-mi:"MI:0096"(pull down)	Chen et al. (1995)	pubmed:7629115|mint:MINT-6825222|doi:10.1074/jbc.270.30.18060	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8592936|mint:MINT-6825247	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR018247|interpro:IPR028846|mint:P21457|rcsb pdb:1IKU|rcsb pdb:1JSA|rcsb pdb:1LA3|rcsb pdb:1OMR|rcsb pdb:1OMV|rcsb pdb:1REC|rcsb pdb:2HET|ensembl:ENSBTAG00000025088(gene)|ensembl:ENSBTAT00000035069(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0016020"(membrane)|go:"GO:0043204"(perikaryon)|go:"GO:0051924"(regulation of calcium ion transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:2I94|rcsb pdb:4M2O|rcsb pdb:4M2Q|rcsb pdb:4MLW|rcsb pdb:4YI8|rcsb pdb:4YI9|rcsb pdb:4M2P|refseq:NP_776590.1|mint:MINT-6825248(identity)|uniprotkb:P21457(P21457)	mint:Q6B856|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007399"(nervous system development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|rcsb pdb:1SA0|rcsb pdb:1SA1|rcsb pdb:1TVK|rcsb pdb:1Z2B|rcsb pdb:2P4N|rcsb pdb:2WBE|rcsb pdb:2XRP|rcsb pdb:3DCO|rcsb pdb:3DU7|rcsb pdb:3E22|rcsb pdb:3IZ0|rcsb pdb:3J1T|rcsb pdb:3J1U|rcsb pdb:3J2U|rcsb pdb:4AQV|rcsb pdb:4AQW|rcsb pdb:4ATU|rcsb pdb:4ATX|rcsb pdb:4CK5|rcsb pdb:4CK6|rcsb pdb:4CK7|rcsb pdb:4I4T|rcsb pdb:4I50|rcsb pdb:4I55|rcsb pdb:4IHJ|rcsb pdb:4IIJ|rcsb pdb:4O2A|rcsb pdb:4O2B|rcsb pdb:4O4H|rcsb pdb:4O4I|rcsb pdb:4O4J|rcsb pdb:4O4L|rcsb pdb:4TUY|rcsb pdb:4TV8|rcsb pdb:4TV9|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXR|rcsb pdb:4UXS|rcsb pdb:4UXT|rcsb pdb:4UXY|rcsb pdb:4UY0|rcsb pdb:4YJ2|rcsb pdb:4YJ3|rcsb pdb:5EIB|rcsb pdb:5EZY|rcsb pdb:5GON|rcsb pdb:5H74|rcsb pdb:5H7O|rcsb pdb:5HNW|rcsb pdb:5HNX|rcsb pdb:5HNY|rcsb pdb:5HNZ|rcsb pdb:5ITZ|rcsb pdb:5IYZ|rcsb pdb:5J2T|rcsb pdb:5J2U|rcsb pdb:5JH7|rcsb pdb:5JVD|rcsb pdb:5LA6|rcsb pdb:5LOV|rcsb pdb:5LP6|rcsb pdb:5LXS|rcsb pdb:5LXT|rcsb pdb:5LYJ|rcsb pdb:5M50|rcsb pdb:5M54|rcsb pdb:5M5C|rcsb pdb:5M5I|rcsb pdb:5M5L|rcsb pdb:5M5M|rcsb pdb:5M5N|rcsb pdb:5M5O|rcsb pdb:5M7G|rcsb pdb:5M8D|rcsb pdb:5M8G|rcsb pdb:5MF4|rcsb pdb:5ND2|rcsb pdb:5ND3|rcsb pdb:5ND4|rcsb pdb:5ND7|rcsb pdb:5NFZ|rcsb pdb:5NG1|rcsb pdb:5NJH|rcsb pdb:5NM5|rcsb pdb:5NQT|rcsb pdb:5NQU|rcsb pdb:5O7A|rcsb pdb:5OSK|rcsb pdb:5OV7|rcsb pdb:5S4L|rcsb pdb:5S4M|rcsb pdb:5S4N|rcsb pdb:5S4O|rcsb pdb:5S4P|rcsb pdb:5S4Q|rcsb pdb:5S4R|rcsb pdb:5S4S|rcsb pdb:5S4T|rcsb pdb:5S4U|rcsb pdb:5S4V|rcsb pdb:5M7E|rcsb pdb:5S4W|rcsb pdb:5S4X|rcsb pdb:5S4Y|rcsb pdb:5S4Z|rcsb pdb:5S50|rcsb pdb:5S51|rcsb pdb:5S52|rcsb pdb:5S53|rcsb pdb:5S54|rcsb pdb:5S55|rcsb pdb:5S56|rcsb pdb:5S57|rcsb pdb:5S58|rcsb pdb:5S59|rcsb pdb:5S5A|rcsb pdb:5S5B|rcsb pdb:5S5C|rcsb pdb:5S5D|rcsb pdb:5S5E|rcsb pdb:5S5F|rcsb pdb:5S5G|rcsb pdb:5S5H|rcsb pdb:5S5I|rcsb pdb:5S5J|rcsb pdb:5S5K|rcsb pdb:5S5L|rcsb pdb:5S5M|rcsb pdb:5S5N|rcsb pdb:5S5O|rcsb pdb:5S5P|rcsb pdb:5S5Q|rcsb pdb:5S5R|rcsb pdb:5S5S|rcsb pdb:5S5T|rcsb pdb:5S5U|rcsb pdb:5S5V|rcsb pdb:5S5W|rcsb pdb:5S5X|rcsb pdb:5S5Y|rcsb pdb:5S5Z|rcsb pdb:5S60|rcsb pdb:5S61|rcsb pdb:5S62|rcsb pdb:5S63|rcsb pdb:5S64|rcsb pdb:5S65|rcsb pdb:5S66|rcsb pdb:5S67|rcsb pdb:5XAF|rcsb pdb:5XAG|rcsb pdb:5XLT|rcsb pdb:5XLZ|rcsb pdb:5YZ3|rcsb pdb:5Z4P|rcsb pdb:5Z4U|rcsb pdb:5ZXH|rcsb pdb:6AGK|rcsb pdb:6BBN|rcsb pdb:6F7C|rcsb pdb:6EG5|rcsb pdb:6FII|rcsb pdb:6FJF|rcsb pdb:6FJM|rcsb pdb:6FKJ|rcsb pdb:6FKL|rcsb pdb:6GF3|rcsb pdb:6GJ4|rcsb pdb:6GZE|rcsb pdb:6HX8|rcsb pdb:6I5C|rcsb pdb:6JCJ|rcsb pdb:6K9V|rcsb pdb:6KNZ|rcsb pdb:6N47|rcsb pdb:6OJQ|rcsb pdb:6QQN|rcsb pdb:6QTN|rcsb pdb:6REV|rcsb pdb:6RF2|rcsb pdb:6RF8|rcsb pdb:6RFD|rcsb pdb:6S8K|rcsb pdb:6S9E|rcsb pdb:6SES|rcsb pdb:6WVL|rcsb pdb:6WVM|rcsb pdb:6WVR|rcsb pdb:6Y6D|rcsb pdb:6ZWB|rcsb pdb:6ZWC|rcsb pdb:7JFR|refseq:NP_001003900.1|dip:DIP-47524N|mint:MINT-6825251(identity)|uniprotkb:Q6B856(Q6B856)	-	comment:mint|function:Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse	comment:mint|function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain	figure legend:F1A|comment:homomint|comment:mint	taxid:9913(bovin-retina)|taxid:9913(Bovine retina)	-	2009/01/23	2014/10/16	rogid:EPz6+aiLYRgBW2NlAy6p7LND5hI9913	rogid:sluQMryNuOvp6xlV558+agiRwvE9913	intact-crc:E26C90BE45E179F8|rigid:7wR3MQyQOeqY02OWgv83+/jbsjg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P28327	uniprotkb:P21457	intact:EBI-7865560|intact:MINT-1507451|ensembl:ENSBTAP00000042484	intact:EBI-8592784|ensembl:ENSBTAP00000034949|intact:MINT-1507490	psi-mi:grk1_bovin(display_long)|uniprotkb:GRK1(gene name)|psi-mi:GRK1(display_short)|uniprotkb:RHOK(gene name synonym)|uniprotkb:G protein-coupled receptor kinase 1(gene name synonym)	psi-mi:reco_bovin(display_long)|uniprotkb:RCVRN(gene name)|psi-mi:RCVRN(display_short)|uniprotkb:RCV1(gene name synonym)|uniprotkb:p26(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chen et al. (1995)	pubmed:7629115|mint:MINT-6825222|doi:10.1074/jbc.270.30.18060	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8592957|mint:MINT-6825260	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007601"(visual perception)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032965|interpro:IPR036305|interpro:IPR037716|mint:P28327|rcsb pdb:2I94|rcsb pdb:3C4W|rcsb pdb:3C4X|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:3C4Y|rcsb pdb:3C4Z|rcsb pdb:3C50|rcsb pdb:3C51|rcsb pdb:3QC9|rcsb pdb:3T8O|rcsb pdb:4L9I|rcsb pdb:4PNI|rcsb pdb:4WBO|go:"GO:0050254"(rhodopsin kinase activity)|go:"GO:0097381"(photoreceptor disc membrane)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|refseq:NP_776598.1|ensembl:ENSBTAG00000019963(gene)|ensembl:ENSBTAT00000045068(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|mint:MINT-6825264(identity)|uniprotkb:P28327(P28327)	interpro:IPR018247|interpro:IPR028846|mint:P21457|rcsb pdb:1IKU|rcsb pdb:1JSA|rcsb pdb:1LA3|rcsb pdb:1OMR|rcsb pdb:1OMV|rcsb pdb:1REC|rcsb pdb:2HET|ensembl:ENSBTAG00000025088(gene)|ensembl:ENSBTAT00000035069(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0016020"(membrane)|go:"GO:0043204"(perikaryon)|go:"GO:0051924"(regulation of calcium ion transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:2I94|rcsb pdb:4M2O|rcsb pdb:4M2Q|rcsb pdb:4MLW|rcsb pdb:4YI8|rcsb pdb:4YI9|rcsb pdb:4M2P|refseq:NP_776590.1|mint:MINT-6825261(identity)|uniprotkb:P21457(P21457)	-	comment:mint|function:Phosphorylates rhodopsin thereby initiating its deactivation	comment:mint|function:Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse	figure legend:F1B|comment:mint	taxid:9913(bovin-retina)|taxid:9913(Bovine retina)	-	2009/01/23	2014/10/16	rogid:eM0swfTKn7hxl0UaF0fUxQW6DuI9913	rogid:EPz6+aiLYRgBW2NlAy6p7LND5hI9913	intact-crc:ED02EFE6C7C7C448|rigid:yY0XaR/CLk/HJNu/1vkJ/3gkiOo	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0396"(predetermined participant)