#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P18146 uniprotkb:O95863 intact:EBI-2834611|ensembl:ENSP00000239938 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 psi-mi:egr1_human(display_long)|uniprotkb:EGR1(gene name)|psi-mi:EGR1(display_short)|uniprotkb:KROX24(gene name synonym)|uniprotkb:ZNF225(gene name synonym)|uniprotkb:AT225(gene name synonym)|uniprotkb:Nerve growth factor-induced protein A(gene name synonym)|uniprotkb:Transcription factor ETR103(gene name synonym)|uniprotkb:Transcription factor Zif268(gene name synonym)|uniprotkb:Zinc finger protein 225(gene name synonym)|uniprotkb:Zinc finger protein Krox-24(gene name synonym) psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hu et al. (2010) pubmed:20121949|imex:IM-15637|mint:MINT-7384875|doi:10.1111/j.1742-4658.2009.07553 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7787945|mint:MINT-7384899|imex:IM-15637-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000239938|go:"GO:0072110"(glomerular mesangial cell proliferation)|go:"GO:0072303"(positive regulation of glomerular metanephric mesangial cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098759"(cellular response to interleukin-8)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000182"(regulation of progesterone biosynthetic process)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR021839|interpro:IPR021849|interpro:IPR036236|mint:P18146|rcsb pdb:4R2A|rcsb pdb:4R2C|rcsb pdb:4R2D|rcsb pdb:4X9J|rcsb pdb:5N14|reactome:R-HSA-8943724|go:"GO:0071506"(cellular response to mycophenolic acid)|ensembl:ENSG00000120738(gene)|ensembl:ENST00000239938(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032868"(response to insulin)|go:"GO:0033233"(regulation of protein sumoylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0044849"(estrous cycle)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:0061418"(regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071504"(cellular response to heparin)|reactome:R-HSA-9031628|reactome:R-HSA-909733|refseq:NP_001955.1|mint:MINT-7384902(identity) refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N|mint:MINT-7384901(identity) - - - comment:homomint|figure legend:f7|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).") - 2009/12/15 2014/10/16 rogid:7JnUP8JJaEG/d72DbadDN/gibQ89606 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 intact-crc:8461C16A1F7E9C02|rigid:lnkdfE8eT5/U/xut/ybdncxazo4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P08047 uniprotkb:P18146 intact:EBI-298336|uniprotkb:Q86TN8|uniprotkb:Q9H3Q5|uniprotkb:Q9NR51|uniprotkb:Q9NY21|uniprotkb:Q9NYE7|intact:EBI-28977878|ensembl:ENSP00000329357|uniprotkb:E4Z9M7|uniprotkb:G5E9M8 intact:EBI-2834611|ensembl:ENSP00000239938 psi-mi:sp1_human(display_long)|uniprotkb:SP1(gene name)|psi-mi:SP1(display_short)|uniprotkb:TSFP1(gene name synonym) psi-mi:egr1_human(display_long)|uniprotkb:EGR1(gene name)|psi-mi:EGR1(display_short)|uniprotkb:KROX24(gene name synonym)|uniprotkb:ZNF225(gene name synonym)|uniprotkb:AT225(gene name synonym)|uniprotkb:Nerve growth factor-induced protein A(gene name synonym)|uniprotkb:Transcription factor ETR103(gene name synonym)|uniprotkb:Transcription factor Zif268(gene name synonym)|uniprotkb:Zinc finger protein 225(gene name synonym)|uniprotkb:Zinc finger protein Krox-24(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hu et al. (2010) pubmed:20121949|imex:IM-15637|mint:MINT-7384875|doi:10.1111/j.1742-4658.2009.07553 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7787957|mint:MINT-7384908|imex:IM-15637-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003100.1|refseq:NP_612482.2|ensembl:ENSG00000185591(gene)|ensembl:ENST00000327443(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1904828"(positive regulation of hydrogen sulfide biosynthetic process)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P08047|rcsb pdb:1SP1|rcsb pdb:1SP2|rcsb pdb:1VA1|rcsb pdb:1VA2|rcsb pdb:1VA3|rcsb pdb:6PV0|rcsb pdb:6PV1|rcsb pdb:6PV2|rcsb pdb:6PV3|rcsb pdb:6UCO|rcsb pdb:6UCP|reactome:R-HSA-1989781|reactome:R-HSA-2173796|reactome:R-HSA-2426168|reactome:R-HSA-2559585|reactome:R-HSA-6807505|reactome:R-HSA-9018519|ensembl:ENSP00000329357|ensembl:ENST00000426431|ensembl:ENSP00000404263|refseq:NP_001238754.1|refseq:XP_011536998.1|dip:DIP-36N|mint:MINT-7384912(identity) ensembl:ENSP00000239938|go:"GO:0072110"(glomerular mesangial cell proliferation)|go:"GO:0072303"(positive regulation of glomerular metanephric mesangial cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098759"(cellular response to interleukin-8)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000182"(regulation of progesterone biosynthetic process)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR021839|interpro:IPR021849|interpro:IPR036236|mint:P18146|rcsb pdb:4R2A|rcsb pdb:4R2C|rcsb pdb:4R2D|rcsb pdb:4X9J|rcsb pdb:5N14|reactome:R-HSA-8943724|go:"GO:0071506"(cellular response to mycophenolic acid)|ensembl:ENSG00000120738(gene)|ensembl:ENST00000239938(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032868"(response to insulin)|go:"GO:0033233"(regulation of protein sumoylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0044849"(estrous cycle)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:0061418"(regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071504"(cellular response to heparin)|reactome:R-HSA-9031628|reactome:R-HSA-909733|refseq:NP_001955.1|mint:MINT-7384910(identity) - - - comment:homomint|figure legend:f7|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).") - 2009/12/15 2014/10/16 rogid:mrIGsFyZTBVulhjVjVxNjFnTm5c9606 rogid:7JnUP8JJaEG/d72DbadDN/gibQ89606 intact-crc:2A1AFF760D127C4C|rigid:BO2ViCi1Wsnw/zJ0qN+8PLXMark false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)