#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q03497	uniprotkb:P25628	intact:EBI-18285|uniprotkb:D3DKQ8|ensemblfungi:YHL007C	intact:EBI-2801|uniprotkb:D6VR57|ensemblfungi:YCR048W	psi-mi:ste20_yeast(display_long)|uniprotkb:STE20(gene name)|psi-mi:STE20(display_short)|uniprotkb:YHL007C(locus name)	psi-mi:are1_yeast(display_long)|uniprotkb:ARE1(gene name)|psi-mi:ARE1(display_short)|uniprotkb:SAT2(gene name synonym)|uniprotkb:YCR048W(locus name)|uniprotkb:YCR48W(orf name)|uniprotkb:Sterol-ester synthase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lin et al. (2009)	pubmed:20050180|imex:IM-15456|mint:MINT-7291407|doi:10.1111/j.1742-4658.2009.07433	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7698104|mint:MINT-7291412|imex:IM-15456-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011856.1|sgd:S000000999|ensemblfungi:YHL007C(gene)|ensemblfungi:YHL007C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|reactome:R-SCE-389359|interpro:IPR036936|reactome:R-SCE-5627123|reactome:R-SCE-5687128|reactome:R-SCE-9013405|reactome:R-SCE-9013406|rcsb pdb:2KYM|rcsb pdb:2LCS|rcsb pdb:2RQW|reactome:R-SCE-2029482|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035376"(sterol import)|go:"GO:0035404"(histone-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044025"("histone kinase activity (H2B-S14 specific)")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|dip:DIP-712N|mint:Q03497|mint:MINT-7291414(identity)	refseq:NP_009978.1|sgd:S000000644|dip:DIP-4998N|mint:P25628|ensemblfungi:YCR048W(gene)|ensemblfungi:YCR048W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008204"(ergosterol metabolic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0034737"(ergosterol O-acyltransferase activity)|go:"GO:0034738"(lanosterol O-acyltransferase activity)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|interpro:IPR014371(Sterol O-acyltransferase, ACAT/DAG/ARE types)|mint:MINT-7291415(identity)	-	crc64:69C1C12F5B87733C	crc64:FF72EFB9238B2205	figure legend:F4|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/10/13	2014/10/16	rogid:ammX6PwJCeyVjNxJ2UJUBrZt9mM559292	rogid:tb8axrzq5QBkRqSVY2TLO+zDBR0559292	intact-crc:C415EB91BBDF3E23|rigid:IC1ZrpLAEthPfS80IJQQD53ZbdY	false	glutathione s tranferase tag:?-?(MINT-7291416)	myc tag:?-?(MINT-7291420)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P53629	uniprotkb:Q03497	intact:EBI-2808|uniprotkb:Q12673|uniprotkb:D6W1J4|ensemblfungi:YNR019W	intact:EBI-18285|uniprotkb:D3DKQ8|ensemblfungi:YHL007C	psi-mi:are2_yeast(display_long)|uniprotkb:ARE2(gene name)|psi-mi:ARE2(display_short)|uniprotkb:SAT1(gene name synonym)|uniprotkb:YNR019W(locus name)|uniprotkb:N3206(orf name)|uniprotkb:Sterol-ester synthase 2(gene name synonym)	psi-mi:ste20_yeast(display_long)|uniprotkb:STE20(gene name)|psi-mi:STE20(display_short)|uniprotkb:YHL007C(locus name)	psi-mi:"MI:0096"(pull down)	Lin et al. (2009)	pubmed:20050180|imex:IM-15456|mint:MINT-7291407|doi:10.1111/j.1742-4658.2009.07433	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7698138|mint:MINT-7291424|imex:IM-15456-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014416.1|sgd:S000005302|dip:DIP-4050N|mint:P53629|ensemblfungi:YNR019W(gene)|ensemblfungi:YNR019W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008204"(ergosterol metabolic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034737"(ergosterol O-acyltransferase activity)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|interpro:IPR014371(Sterol O-acyltransferase, ACAT/DAG/ARE types)|mint:MINT-7291426(identity)	refseq:NP_011856.1|sgd:S000000999|ensemblfungi:YHL007C(gene)|ensemblfungi:YHL007C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|reactome:R-SCE-389359|interpro:IPR036936|reactome:R-SCE-5627123|reactome:R-SCE-5687128|reactome:R-SCE-9013405|reactome:R-SCE-9013406|rcsb pdb:2KYM|rcsb pdb:2LCS|rcsb pdb:2RQW|reactome:R-SCE-2029482|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035376"(sterol import)|go:"GO:0035404"(histone-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044025"("histone kinase activity (H2B-S14 specific)")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|dip:DIP-712N|mint:Q03497|mint:MINT-7291430(identity)	-	crc64:035FC4ED9C7CD830	crc64:69C1C12F5B87733C	figure legend:F4|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/10/13	2014/10/16	rogid:19pHOCLa6/S7I+HrOY1OAtUJ3ww559292	rogid:ammX6PwJCeyVjNxJ2UJUBrZt9mM559292	intact-crc:1F4BF0147228FC18|rigid:wpb8lqzEwo1jOHvVQEQJuAWIdZE	false	myc tag:?-?(MINT-7291427)	glutathione s tranferase tag:?-?(MINT-7291431)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25340	uniprotkb:Q03497	intact:EBI-6558|uniprotkb:D6VUC5|uniprotkb:E9P929|ensemblfungi:YGL012W	intact:EBI-18285|uniprotkb:D3DKQ8|ensemblfungi:YHL007C	psi-mi:erg4_yeast(display_long)|uniprotkb:ERG4(gene name)|psi-mi:ERG4(display_short)|uniprotkb:YGL012W(locus name)|uniprotkb:YGL022(orf name)|uniprotkb:"Sterol Delta(24(28))-reductase"(gene name synonym)|uniprotkb:"C-24(28) sterol reductase"(gene name synonym)	psi-mi:ste20_yeast(display_long)|uniprotkb:STE20(gene name)|psi-mi:STE20(display_short)|uniprotkb:YHL007C(locus name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Lin et al. (2009)	pubmed:20050180|imex:IM-15456|mint:MINT-7291407|doi:10.1111/j.1742-4658.2009.07433	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7698164|mint:MINT-7291441|imex:IM-15456-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011503.1|sgd:S000002980|mint:P25340|dip:DIP-7177N|ensemblfungi:YGL012W(gene)|ensemblfungi:YGL012W_mRNA(transcript)|go:"GO:0000246"("delta24(24-1) sterol reductase activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR018083|mint:MINT-7291443(identity)	refseq:NP_011856.1|sgd:S000000999|ensemblfungi:YHL007C(gene)|ensemblfungi:YHL007C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|reactome:R-SCE-389359|interpro:IPR036936|reactome:R-SCE-5627123|reactome:R-SCE-5687128|reactome:R-SCE-9013405|reactome:R-SCE-9013406|rcsb pdb:2KYM|rcsb pdb:2LCS|rcsb pdb:2RQW|reactome:R-SCE-2029482|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035376"(sterol import)|go:"GO:0035404"(histone-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044025"("histone kinase activity (H2B-S14 specific)")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|dip:DIP-712N|mint:Q03497|mint:MINT-7291447(identity)	-	-	crc64:69C1C12F5B87733C	figure legend:F3B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/10/13	2014/10/16	rogid:BVxKi7zDnF20xAPBIry0VNTICCw559292	rogid:ammX6PwJCeyVjNxJ2UJUBrZt9mM559292	intact-crc:167696E3A2A486BE|rigid:HJJYvaXqzWf/2/Gp3oMSnHu8sSs	false	tag:?-?(MINT-7291444)	tag:?-?(MINT-7291448)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03497	uniprotkb:P16603	intact:EBI-18285|uniprotkb:D3DKQ8|ensemblfungi:YHL007C	intact:EBI-11940|ensemblfungi:YHR042W|uniprotkb:D3DKZ0	psi-mi:ste20_yeast(display_long)|uniprotkb:STE20(gene name)|psi-mi:STE20(display_short)|uniprotkb:YHL007C(locus name)	psi-mi:ncpr_yeast(display_long)|uniprotkb:NCP1(gene name)|psi-mi:NCP1(display_short)|uniprotkb:NCPR1(gene name synonym)|uniprotkb:PRD1(gene name synonym)|uniprotkb:CPR1(gene name synonym)|uniprotkb:YHR042W(locus name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Lin et al. (2009)	pubmed:20050180|imex:IM-15456|mint:MINT-7291407|doi:10.1111/j.1742-4658.2009.07433	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7698198|mint:MINT-7291468|imex:IM-15456-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011856.1|sgd:S000000999|ensemblfungi:YHL007C(gene)|ensemblfungi:YHL007C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|reactome:R-SCE-389359|interpro:IPR036936|reactome:R-SCE-5627123|reactome:R-SCE-5687128|reactome:R-SCE-9013405|reactome:R-SCE-9013406|rcsb pdb:2KYM|rcsb pdb:2LCS|rcsb pdb:2RQW|reactome:R-SCE-2029482|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035376"(sterol import)|go:"GO:0035404"(histone-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044025"("histone kinase activity (H2B-S14 specific)")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|dip:DIP-712N|mint:Q03497|mint:MINT-7291474(identity)	ensemblfungi:YHR042W(gene)|ensemblfungi:YHR042W_mRNA(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0003959"(NADPH dehydrogenase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0010181"(FMN binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0005739"(mitochondrion)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR023208|interpro:IPR039261|rcsb pdb:2BF4|rcsb pdb:2BN4|rcsb pdb:2BPO|rcsb pdb:3FJO|reactome:R-SCE-1222556|reactome:R-SCE-1474151|reactome:R-SCE-203615|reactome:R-SCE-392154|reactome:R-SCE-5218920|reactome:R-SCE-5578775|reactome:R-SCE-9009391|reactome:R-SCE-9033241|interpro:IPR029039|refseq:NP_011908.1|sgd:S000001084|mint:P16603|dip:DIP-8294N|mint:MINT-7291470(identity)	-	crc64:69C1C12F5B87733C	-	figure legend:F3B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/10/13	2014/10/16	rogid:ammX6PwJCeyVjNxJ2UJUBrZt9mM559292	rogid:l8faixht4sd0KQhbt2DadH/8BPw559292	intact-crc:84A40D4D9731B04E|rigid:iuT+eyM0jl11lBaNtvDacEb16YQ	false	tag:?-?(MINT-7291475)	tag:?-?(MINT-7291471)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38626	uniprotkb:Q03497	intact:EBI-2048224|uniprotkb:D6VVN9|ensemblfungi:YIL043C	intact:EBI-18285|uniprotkb:D3DKQ8|ensemblfungi:YHL007C	psi-mi:ncb5r_yeast(display_long)|uniprotkb:CBR(gene name synonym)|uniprotkb:CBR5(gene name synonym)|uniprotkb:Microsomal cytochrome b reductase(gene name synonym)|uniprotkb:P35(gene name synonym)|uniprotkb:YIL043C(locus name)|uniprotkb:CBR1(gene name)|psi-mi:CBR1(display_short)	psi-mi:ste20_yeast(display_long)|uniprotkb:STE20(gene name)|psi-mi:STE20(display_short)|uniprotkb:YHL007C(locus name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Lin et al. (2009)	pubmed:20050180|imex:IM-15456|mint:MINT-7291407|doi:10.1111/j.1742-4658.2009.07433	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7698181|mint:MINT-7291456|imex:IM-15456-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012221.2|sgd:S000001305|interpro:IPR017927|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR017938|mint:P38626|interpro:IPR039261|ensemblfungi:YIL043C(gene)|ensemblfungi:YIL043C_mRNA(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:MINT-7291458(identity)	refseq:NP_011856.1|sgd:S000000999|ensemblfungi:YHL007C(gene)|ensemblfungi:YHL007C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|reactome:R-SCE-389359|interpro:IPR036936|reactome:R-SCE-5627123|reactome:R-SCE-5687128|reactome:R-SCE-9013405|reactome:R-SCE-9013406|rcsb pdb:2KYM|rcsb pdb:2LCS|rcsb pdb:2RQW|reactome:R-SCE-2029482|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035376"(sterol import)|go:"GO:0035404"(histone-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044025"("histone kinase activity (H2B-S14 specific)")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|dip:DIP-712N|mint:Q03497|mint:MINT-7291462(identity)	-	-	crc64:69C1C12F5B87733C	figure legend:F3B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/10/13	2014/10/16	rogid:BxHKVXPxqbv+CNAKhESXsL5hG8k559292	rogid:ammX6PwJCeyVjNxJ2UJUBrZt9mM559292	intact-crc:E51DF8941F33C279|rigid:+YFzY79/Daxr+DHRafOy/s2z0hU	false	tag:?-?(MINT-7291459)	tag:?-?(MINT-7291463)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29366	uniprotkb:P48562	intact:EBI-3508|uniprotkb:D6VQJ6|ensemblfungi:YBR200W	intact:EBI-4750|uniprotkb:D6W0P6|ensemblfungi:YNL298W	psi-mi:bem1_yeast(display_long)|uniprotkb:Suppressor of RHO3 protein 1(gene name synonym)|uniprotkb:BEM1(gene name)|psi-mi:BEM1(display_short)|uniprotkb:SRO1(gene name synonym)|uniprotkb:YBR200W(locus name)|uniprotkb:YBR1412(orf name)	psi-mi:cla4_yeast(display_long)|uniprotkb:CLA4(gene name)|psi-mi:CLA4(display_short)|uniprotkb:N0450(orf name)|uniprotkb:YNL298W(locus name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Lin et al. (2009)	pubmed:20050180|imex:IM-15456|mint:MINT-7291407|doi:10.1111/j.1742-4658.2009.07433	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7698250|mint:MINT-7291492|imex:IM-15456-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000404|refseq:NP_009759.3|dip:DIP-688N|mint:P29366|ensemblfungi:YBR200W(gene)|ensemblfungi:YBR200W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR030507|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR036028|interpro:IPR036871|rcsb pdb:1IP9|rcsb pdb:1IPG|rcsb pdb:2CZO|rcsb pdb:2KFK|rcsb pdb:2RQV|rcsb pdb:2RQW|rcsb pdb:2V6V|reactome:R-SCE-5668599|mint:MINT-7291494(identity)	refseq:NP_014101.1|sgd:S000005242|dip:DIP-2276N|mint:P48562|ensemblfungi:YNL298W(gene)|ensemblfungi:YNL298W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016301"(kinase activity)|go:"GO:0019236"(response to pheromone)|go:"GO:0019899"(enzyme binding)|go:"GO:0031106"(septin ring organization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035376"(sterol import)|go:"GO:0035404"(histone-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR033923|interpro:IPR036936|reactome:R-SCE-2029482|reactome:R-SCE-389359|reactome:R-SCE-5627123|reactome:R-SCE-5687128|reactome:R-SCE-9013405|reactome:R-SCE-9013406|mint:MINT-7291498(identity)	-	crc64:FB6C525AE9A19181	-	figure legend:F3B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/10/13	2014/10/16	rogid:Fq7WxTviE31ivPWGJoZO5DsUcdg559292	rogid:dRa35JRDBbCIp/ocDOt0m9eb1AA559292	intact-crc:6CEAC89EC62E406E|rigid:UHPKotdCnfoP74rLYaRr8mLC/fU	false	tag:?-?(MINT-7291495)	tag:?-?(MINT-7291499)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29366	uniprotkb:Q03497	intact:EBI-3508|uniprotkb:D6VQJ6|ensemblfungi:YBR200W	intact:EBI-18285|uniprotkb:D3DKQ8|ensemblfungi:YHL007C	psi-mi:bem1_yeast(display_long)|uniprotkb:Suppressor of RHO3 protein 1(gene name synonym)|uniprotkb:BEM1(gene name)|psi-mi:BEM1(display_short)|uniprotkb:SRO1(gene name synonym)|uniprotkb:YBR200W(locus name)|uniprotkb:YBR1412(orf name)	psi-mi:ste20_yeast(display_long)|uniprotkb:STE20(gene name)|psi-mi:STE20(display_short)|uniprotkb:YHL007C(locus name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Lin et al. (2009)	pubmed:20050180|imex:IM-15456|mint:MINT-7291407|doi:10.1111/j.1742-4658.2009.07433	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7698233|mint:MINT-7291480|imex:IM-15456-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000404|refseq:NP_009759.3|dip:DIP-688N|mint:P29366|ensemblfungi:YBR200W(gene)|ensemblfungi:YBR200W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR030507|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR036028|interpro:IPR036871|rcsb pdb:1IP9|rcsb pdb:1IPG|rcsb pdb:2CZO|rcsb pdb:2KFK|rcsb pdb:2RQV|rcsb pdb:2RQW|rcsb pdb:2V6V|reactome:R-SCE-5668599|mint:MINT-7291482(identity)	refseq:NP_011856.1|sgd:S000000999|ensemblfungi:YHL007C(gene)|ensemblfungi:YHL007C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|reactome:R-SCE-389359|interpro:IPR036936|reactome:R-SCE-5627123|reactome:R-SCE-5687128|reactome:R-SCE-9013405|reactome:R-SCE-9013406|rcsb pdb:2KYM|rcsb pdb:2LCS|rcsb pdb:2RQW|reactome:R-SCE-2029482|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035376"(sterol import)|go:"GO:0035404"(histone-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044025"("histone kinase activity (H2B-S14 specific)")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|dip:DIP-712N|mint:Q03497|mint:MINT-7291486(identity)	-	crc64:FB6C525AE9A19181	crc64:69C1C12F5B87733C	figure legend:F3B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/10/13	2014/10/16	rogid:Fq7WxTviE31ivPWGJoZO5DsUcdg559292	rogid:ammX6PwJCeyVjNxJ2UJUBrZt9mM559292	intact-crc:F1DECF89B7A1CEF6|rigid:QCJqHrvfSXBiFYAe6jPo48g8k5Y	false	tag:?-?(MINT-7291483)	tag:?-?(MINT-7291487)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)