#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P34930 uniprotkb:P25685 intact:EBI-7693095|intact:MINT-7384270 intact:EBI-357034|ensembl:ENSP00000254322|uniprotkb:B4DX52 psi-mi:hs71a_pig(display_long)|uniprotkb:Heat shock 70 kDa protein 1(gene name synonym)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym) psi-mi:dnjb1_human(display_long)|uniprotkb:DNAJB1(gene name)|psi-mi:DNAJB1(display_short)|uniprotkb:DNAJ1(gene name synonym)|uniprotkb:HDJ1(gene name synonym)|uniprotkb:HSPF1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1(gene name synonym)|uniprotkb:Human DnaJ protein 1(gene name synonym)|uniprotkb:DnaJ protein homolog 1(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Yamamoto et al. (2010) pubmed:20026329|imex:IM-15453|mint:MINT-7384265|mint:d-09-01859 taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7693089|mint:MINT-7384283|imex:IM-15453-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007041"(lysosomal transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:1901673"(regulation of mitotic spindle assembly)|mint:P34930|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:MINT-7384285(identity) dip:DIP-41180N|ensembl:ENSG00000132002(gene)|ensembl:ENST00000254322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|refseq:NP_006136.1|refseq:XP_006722796.1|refseq:NP_001287843.1|refseq:NP_001300893.1|refseq:XP_011526258.1|refseq:XP_006722797.1|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061827"(sperm head)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR018253|interpro:IPR036869|mint:P25685|rcsb pdb:1HDJ|rcsb pdb:2QLD|rcsb pdb:3AGX|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:4WB7|rcsb pdb:6BYR|rcsb pdb:6WJF|rcsb pdb:6WJG|rcsb pdb:6Z5N|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-5687128|interpro:IPR008971(HSP40/DnaJ peptide-binding)|mint:MINT-7384286(identity) - comment:mint - comment:mint|figure legend:f5b sf1 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:21.3x10^-6(molar) 2009/12/14 2014/10/16 rogid:rUPr+TgBSWKwWu4lawewphg2yrY9823 rogid:8NJHM7hHFc+zqulNiUM9UMxT/ws9606 intact-crc:BB0D1D29B2E2A1C0|rigid:otUjIa/cZZVpSKuYl1WaSiKURhY false - his tag:?-?(MINT-7384289) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34930 uniprotkb:P61823 intact:EBI-7693095|intact:MINT-7384270 intact:EBI-908364|uniprotkb:P00656|uniprotkb:Q9TSF2|uniprotkb:A6QPW8|ensembl:ENSBTAP00000011586 psi-mi:hs71a_pig(display_long)|uniprotkb:Heat shock 70 kDa protein 1(gene name synonym)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym) psi-mi:rnas1_bovin(display_long)|uniprotkb:RNASE1(gene name)|psi-mi:RNASE1(display_short)|uniprotkb:RNS1(gene name synonym)|uniprotkb:RNase 1(gene name synonym)|uniprotkb:RNase A(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Yamamoto et al. (2010) pubmed:20026329|imex:IM-15453|mint:MINT-7384265|mint:d-09-01859 taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7693134|mint:MINT-7384430|imex:IM-15453-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007041"(lysosomal transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:1901673"(regulation of mitotic spindle assembly)|mint:P34930|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:MINT-7384437(identity) refseq:NP_001014408.2|refseq:XP_005211519.1|dip:DIP-36384N|rcsb pdb:3RID|rcsb pdb:3RN3|rcsb pdb:3RSD|rcsb pdb:3RSK|rcsb pdb:3RSP|rcsb pdb:3SRN|rcsb pdb:4AO1|rcsb pdb:4G8V|rcsb pdb:4G8Y|rcsb pdb:4G90|rcsb pdb:4J5Z|rcsb pdb:4J60|rcsb pdb:4J61|rcsb pdb:4J62|rcsb pdb:4J63|rcsb pdb:4J64|rcsb pdb:4J65|rcsb pdb:4J66|rcsb pdb:3RH1|rcsb pdb:4J67|rcsb pdb:4J68|rcsb pdb:4J6A|rcsb pdb:4K7L|rcsb pdb:4K7M|rcsb pdb:4L55|rcsb pdb:4MXF|rcsb pdb:4O36|rcsb pdb:4O37|rcsb pdb:4OKF|rcsb pdb:4OOH|rcsb pdb:4OT4|rcsb pdb:4PEQ|rcsb pdb:4POU|rcsb pdb:4QH3|rcsb pdb:4RAT|rcsb pdb:4RSD|rcsb pdb:4RSK|rcsb pdb:4RTE|rcsb pdb:4S0Q|rcsb pdb:4S18|rcsb pdb:4SRN|rcsb pdb:4WYN|rcsb pdb:4WYP|rcsb pdb:4WYZ|rcsb pdb:4YGW|rcsb pdb:4ZZ4|rcsb pdb:5D6U|rcsb pdb:5D97|rcsb pdb:5E5E|rcsb pdb:5E5F|rcsb pdb:5ET4|rcsb pdb:5JLG|rcsb pdb:5JMG|rcsb pdb:4J69|rcsb pdb:5JML|rcsb pdb:5NA9|rcsb pdb:5NJ7|rcsb pdb:5OBD|rcsb pdb:5OBE|rcsb pdb:5OGH|rcsb pdb:5OLD|rcsb pdb:5RAT|rcsb pdb:5RSA|rcsb pdb:6ETK|rcsb pdb:6ETL|rcsb pdb:6ETM|rcsb pdb:6ETN|rcsb pdb:6ETO|rcsb pdb:6ETP|rcsb pdb:6ETQ|rcsb pdb:6ETR|rcsb pdb:6F60|rcsb pdb:6GOK|rcsb pdb:6PVU|rcsb pdb:6PVV|rcsb pdb:6PVW|rcsb pdb:6PVX|rcsb pdb:6QE9|rcsb pdb:6RAT|rcsb pdb:6RSA|rcsb pdb:6XHC|rcsb pdb:6XHD|rcsb pdb:6XHE|rcsb pdb:6XHF|rcsb pdb:6XVX|rcsb pdb:6XW0|rcsb pdb:6YO1|rcsb pdb:7RAT|rcsb pdb:7RSA|rcsb pdb:8RAT|rcsb pdb:8RSA|rcsb pdb:9RAT|rcsb pdb:9RSA|rcsb pdb:5OBC|ensembl:ENSBTAG00000008793(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004522"(ribonuclease A activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016829"(lyase activity)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|mint:P61823|rcsb pdb:1A2W|rcsb pdb:1A5P|rcsb pdb:1A5Q|rcsb pdb:1AFK|rcsb pdb:1AFL|rcsb pdb:1AFU|rcsb pdb:1AQP|rcsb pdb:1B6V|rcsb pdb:1BEL|rcsb pdb:1BZQ|rcsb pdb:1C0B|rcsb pdb:1C0C|rcsb pdb:1C8W|rcsb pdb:1C9V|rcsb pdb:1C9X|rcsb pdb:1CJQ|rcsb pdb:1CJR|rcsb pdb:1D5D|rcsb pdb:1D5E|rcsb pdb:1D5H|rcsb pdb:1DFJ|rcsb pdb:1DY5|rcsb pdb:1EIC|rcsb pdb:1EID|rcsb pdb:1EIE|rcsb pdb:1EOS|rcsb pdb:1EOW|rcsb pdb:1F0V|rcsb pdb:1FEV|ensembl:ENSBTAT00000011586(transcript)|rcsb pdb:1FS3|rcsb pdb:1GV7|rcsb pdb:1IZP|rcsb pdb:1IZQ|rcsb pdb:1IZR|rcsb pdb:1J7Z|rcsb pdb:1J80|rcsb pdb:1J81|rcsb pdb:1J82|rcsb pdb:1JN4|rcsb pdb:1JS0|rcsb pdb:1JVT|rcsb pdb:1JVU|rcsb pdb:1JVV|rcsb pdb:1KF2|rcsb pdb:1KF3|rcsb pdb:1KF4|rcsb pdb:1KF5|rcsb pdb:1KF7|rcsb pdb:1KF8|rcsb pdb:1KH8|rcsb pdb:1LSQ|rcsb pdb:1O0F|rcsb pdb:1O0H|rcsb pdb:1O0M|rcsb pdb:1O0N|rcsb pdb:1O0O|rcsb pdb:1QHC|rcsb pdb:1RAR|rcsb pdb:1RAS|rcsb pdb:1RAT|rcsb pdb:1RBB|rcsb pdb:1RBC|rcsb pdb:1RBD|rcsb pdb:1RBE|rcsb pdb:1RBF|rcsb pdb:1RBG|rcsb pdb:1RBH|rcsb pdb:1RBI|rcsb pdb:1RBJ|rcsb pdb:1RBN|rcsb pdb:1RBW|rcsb pdb:1RBX|rcsb pdb:1RCA|rcsb pdb:1RCN|rcsb pdb:1RHA|rcsb pdb:1RHB|rcsb pdb:1RNC|rcsb pdb:1RND|rcsb pdb:1RNM|rcsb pdb:1RNN|rcsb pdb:1RNO|rcsb pdb:1RNQ|rcsb pdb:1RNU|rcsb pdb:1RNV|rcsb pdb:1RNW|rcsb pdb:1RNX|rcsb pdb:1RNY|rcsb pdb:1RNZ|rcsb pdb:1ROB|rcsb pdb:1RPF|rcsb pdb:1RPG|rcsb pdb:1RPH|rcsb pdb:1RSM|rcsb pdb:1RTA|rcsb pdb:1RTB|rcsb pdb:1RUV|rcsb pdb:1SRN|rcsb pdb:1SSA|rcsb pdb:1SSB|rcsb pdb:1SSC|rcsb pdb:1U1B|rcsb pdb:1UN5|rcsb pdb:1W4O|rcsb pdb:1W4P|rcsb pdb:1W4Q|rcsb pdb:1WBU|rcsb pdb:1XPS|rcsb pdb:1XPT|rcsb pdb:1YMN|rcsb pdb:1YMR|rcsb pdb:1YMW|rcsb pdb:1Z3L|rcsb pdb:1Z3M|rcsb pdb:1Z3P|rcsb pdb:1Z6D|rcsb pdb:1Z6S|rcsb pdb:2AAS|rcsb pdb:2APQ|rcsb pdb:2APU|rcsb pdb:2BLP|rcsb pdb:2BLZ|rcsb pdb:2E33|rcsb pdb:2E3W|rcsb pdb:2G4W|rcsb pdb:2G4X|rcsb pdb:2G8Q|rcsb pdb:2G8R|rcsb pdb:2NUI|rcsb pdb:2OP2|rcsb pdb:2OQF|rcsb pdb:2P42|rcsb pdb:2P43|rcsb pdb:2P44|rcsb pdb:2P45|rcsb pdb:2P46|rcsb pdb:2P47|rcsb pdb:2P48|rcsb pdb:2P49|rcsb pdb:2P4A|rcsb pdb:2QCA|rcsb pdb:2RAT|rcsb pdb:2RLN|rcsb pdb:2RNS|rcsb pdb:2W5G|rcsb pdb:2W5I|rcsb pdb:2W5K|rcsb pdb:2W5L|rcsb pdb:2W5M|rcsb pdb:2XOG|rcsb pdb:2XOI|rcsb pdb:3A1R|rcsb pdb:3D6O|rcsb pdb:3D6P|rcsb pdb:3D6Q|rcsb pdb:3D7B|rcsb pdb:3D8Y|rcsb pdb:3D8Z|rcsb pdb:3DH5|rcsb pdb:3DH6|rcsb pdb:3DI7|rcsb pdb:3DI8|rcsb pdb:3DI9|rcsb pdb:3DIB|rcsb pdb:3DIC|rcsb pdb:3DXG|rcsb pdb:3DXH|rcsb pdb:3EUX|rcsb pdb:3EUY|rcsb pdb:3EUZ|rcsb pdb:3EV0|rcsb pdb:3EV1|rcsb pdb:3EV2|rcsb pdb:3EV3|rcsb pdb:3EV4|rcsb pdb:3EV5|rcsb pdb:3EV6|rcsb pdb:3FKZ|rcsb pdb:3FL0|rcsb pdb:3FL1|rcsb pdb:3FL3|rcsb pdb:3I67|rcsb pdb:3I6F|rcsb pdb:3I6H|rcsb pdb:3I6J|rcsb pdb:3I7W|rcsb pdb:3I7X|rcsb pdb:3I7Y|rcsb pdb:3JW1|rcsb pdb:3LXO|rcsb pdb:3MWQ|rcsb pdb:3MWR|rcsb pdb:3MX8|rcsb pdb:3MZQ|rcsb pdb:3MZR|rcsb pdb:3OQY|rcsb pdb:3OQZ|rcsb pdb:3OR0|rcsb pdb:3QL1|rcsb pdb:3QL2|rcsb pdb:3QSK|rcsb pdb:3RAT|mint:MINT-7384433(identity) - comment:mint - figure legend:f5a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:2.26x10^-8(molar) 2009/12/14 2014/10/16 rogid:rUPr+TgBSWKwWu4lawewphg2yrY9823 rogid:ifHI/UwVRIuj5ksIiZPB0pUY+0E9913 intact-crc:C278BC35A8F84A90|rigid:OGrUb1mnL0fFpxpG3tAu2Nfg96I false - binding-associated region:27-44(MINT-7384440) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis)