#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:E7FI45 uniprotkb:Q8TZV1 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505108|ensemblbacteria:AAL82005 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:alba_pyrfu(display_long)|uniprotkb:albA(gene name)|psi-mi:albA(display_short)|uniprotkb:PF1881(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL82005(transcript)|ensemblbacteria:PF1881(gene)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|interpro:IPR013795(Alba, DNA/RNA-binding protein, archaeal)|interpro:IPR002775(Alba, DNA/RNA-binding protein)|refseq:WP_011013020.1|interpro:IPR036882 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:qmWV4Lv8ZfKWtAb+KrBSEnAINl0186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8TH08 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505538|ensemblbacteria:AAL81170 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:atgt_pyrfu(display_long)|uniprotkb:tgtA(gene name)|psi-mi:tgtA(display_short)|uniprotkb:Archaeal tRNA-guanine transglycosylase(gene name synonym)|uniprotkb:PF1046(locus name)|uniprotkb:7-cyano-7-deazaguanine tRNA-ribosyltransferase(gene name synonym) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81170(transcript)|ensemblbacteria:PF1046(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0006400"(tRNA modification)|go:"GO:0016763"(pentosyltransferase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR038250|interpro:IPR029402|interpro:IPR038370|interpro:IPR032729|refseq:WP_011012183.1|interpro:IPR004804(Archaeosine tRNA-ribosyltransferase)|interpro:IPR002478(PUA)|interpro:IPR015947(PUA-like)|interpro:IPR002616(Queuine/other tRNA-ribosyltransferase)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR036511|interpro:IPR036974 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:e0j9GR/H9Wvdrv8d0jCsKAs1SnI186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8TH22 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505483|ensemblbacteria:AAL80150 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:cca_pyrfu(display_long)|uniprotkb:cca(gene name)|psi-mi:cca(display_short)|uniprotkb:tRNA nucleotidyltransferase(gene name synonym)|uniprotkb:tRNA adenylyl-/cytidylyl- transferase(gene name synonym)|uniprotkb:tRNA CCA-pyrophosphorylase(gene name synonym)|uniprotkb:tRNA-NT(gene name synonym)|uniprotkb:PF0026(locus name)|uniprotkb:CCA tRNA nucleotidyltransferase(gene name synonym) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL80150(transcript)|ensemblbacteria:PF0026(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001680"(tRNA 3'-terminal CCA addition)|go:"GO:0005524"(ATP binding)|go:"GO:0016437"(tRNA cytidylyltransferase activity)|go:"GO:0042245"(RNA repair)|go:"GO:0052927"("CTP:tRNA cytidylyltransferase activity")|go:"GO:0052928"("CTP:3'-cytidine-tRNA cytidylyltransferase activity")|go:"GO:0052929"("ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity")|interpro:IPR008229(tRNA nucleotidyltransferase, CCA-adding enzyme)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR011068(Nucleotidyltransferase, class I, C-terminal-like)|interpro:IPR015329(tRNA nucleotidyltransferase, substrate binding)|refseq:WP_011011138.1|interpro:IPR042090|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:GK40dOoIQjakz+hoCNj4DamGHuI186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U1S5 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2504983|ensemblbacteria:AAL81254 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:cmr1a_pyrfu(display_long)|uniprotkb:cmr1-1(gene name)|psi-mi:cmr1-1(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr1-1(gene name synonym)|uniprotkb:PF1130(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81254(transcript)|ensemblbacteria:PF1130(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR007522(CRISPR-associated protein TM1795 family, N-terminal)|rcsb pdb:4W8X|rcsb pdb:4W8Z|refseq:WP_011012270.1|dip:DIP-54364N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:SxmHMZkKYv1zvzBsZcLpo3pdqss186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U3V3 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2504976|ensemblbacteria:AAL80476 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:cmr1b_pyrfu(display_long)|uniprotkb:cmr1-2(gene name)|psi-mi:cmr1-2(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr1-2(gene name synonym)|uniprotkb:PF0352(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL80476(transcript)|ensemblbacteria:PF0352(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR007522(CRISPR-associated protein TM1795 family, N-terminal)|interpro:IPR005537(Protein of unknown function DUF324)|refseq:WP_048059033.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:v90I1NKqpA+tZgtv+rginvdBS4I186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U1S6 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2504936|ensemblbacteria:AAL81253 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U1S7 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2504943|ensemblbacteria:AAL81252 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:cmr3_pyrfu(display_long)|uniprotkb:cmr3(gene name)|psi-mi:cmr3(display_short)|uniprotkb:CRISPR type III-B/RAMP module-associated protein Cmr3(gene name synonym)|uniprotkb:PF1128(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:PF1128(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR010165(CRISPR-associated protein, TM1793)|interpro:IPR019117|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4H4K|ensemblbacteria:AAL81252(transcript)|refseq:WP_011012268.1|dip:DIP-54365N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:vxqihIKFjSErsbCL6/OiH04DOlY186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U1S9 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2504950|ensemblbacteria:AAL81250 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:cmr4_pyrfu(display_long)|uniprotkb:cmr4(gene name)|psi-mi:cmr4(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr4(gene name synonym)|uniprotkb:Target RNase Cmr4(gene name synonym)|uniprotkb:PF1126(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81250(transcript)|ensemblbacteria:PF1126(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR013410(CRISPR-associated RAMP Cmr4)|rcsb pdb:4RDP|rcsb pdb:4W8W|rcsb pdb:4WNZ|refseq:WP_011012266.1|dip:DIP-54367N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:Nm72GeycBUn1mj6QxSAdnMFsszA186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U1T0 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2504964|ensemblbacteria:AAL81249 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:cmr5_pyrfu(display_long)|uniprotkb:cmr5(gene name)|psi-mi:cmr5(display_short)|uniprotkb:CRISPR type III-B/RAMP module-associated protein Cmr5(gene name synonym)|uniprotkb:PF1125(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81249(transcript)|ensemblbacteria:PF1125(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR010160(CRISPR-associated protein, TM1791.1)|interpro:IPR023101|rcsb pdb:4GKF|refseq:WP_011012265.1|dip:DIP-54369N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:vy8RHUFrrtBu6msl3Scl3awQtmM186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U1T1 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2504957|ensemblbacteria:AAL81248 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:cmr6_pyrfu(display_long)|uniprotkb:cmr6(gene name)|psi-mi:cmr6(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr6(gene name synonym)|uniprotkb:PF1124(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81248(transcript)|ensemblbacteria:PF1124(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR010172(CRISPR-associated protein, TM1791)|rcsb pdb:4W8V|refseq:WP_011012264.1|dip:DIP-54368N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:puSz7Udnj8h4VthO+EkLW7njqN0186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U152 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505344|ensemblbacteria:AAL81499 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:ef1a_pyrfu(display_long)|uniprotkb:tuf(gene name)|psi-mi:tuf(display_short)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:PF1375(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81499(transcript)|ensemblbacteria:PF1375(gene)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR031157|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|refseq:WP_011012522.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:Zt+ur+f9VfHZm40OrrT++iP9WLc186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U3K2 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505555|ensemblbacteria:AAL80588|uniprotkb:O93720|uniprotkb:Q9UWI2 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:gapor_pyrfu(display_long)|uniprotkb:gor(gene name)|psi-mi:gor(display_short)|uniprotkb:Tungsten-containing glyceraldehyde-3-phosphate ferredoxin oxidoreductase(gene name synonym)|uniprotkb:PF0464(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL80588(transcript)|ensemblbacteria:PF0464(gene)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0043797"("glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) activity")|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR013984(Aldehyde ferredoxin oxidoreductase, domain 2)|interpro:IPR013983(Aldehyde ferredoxin oxidoreductase, N-terminal)|interpro:IPR001203(Aldehyde ferredoxin oxidoreductase, C-terminal)|refseq:WP_011011581.1|interpro:IPR036021|interpro:IPR036503 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:jljY7Rch4GQg8Hb0l+hpOrAkrzc186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U1R5 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505153|ensemblbacteria:AAL81264 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:if2a_pyrfu(display_long)|uniprotkb:eif2a(gene name)|psi-mi:eif2a(display_short)|uniprotkb:eIF-2-alpha(gene name synonym)|uniprotkb:aIF2-alpha(gene name synonym)|uniprotkb:PF1140(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 go:"GO:0003743"(translation initiation factor activity)|ensemblbacteria:AAL81264(transcript)|ensemblbacteria:PF1140(gene)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR022967|interpro:IPR022964|interpro:IPR024055|interpro:IPR024054|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|refseq:WP_011012280.1|interpro:IPR044126 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:IZGr5PmKYfiOvwnA9a5dSLq0BYk186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U3I5 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505077|ensemblbacteria:AAL80605 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:if2b_pyrfu(display_long)|uniprotkb:eif2b(gene name)|psi-mi:eif2b(display_short)|uniprotkb:eIF-2-beta(gene name synonym)|uniprotkb:aIF2-beta(gene name synonym)|uniprotkb:PF0481(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL80605(transcript)|ensemblbacteria:PF0481(gene)|go:"GO:0003743"(translation initiation factor activity)|interpro:IPR004458(Archaeal translation initiation factor aIF-2, beta subunit)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|rcsb pdb:2D74|rcsb pdb:2DCU|refseq:WP_011011598.1|dip:DIP-54411N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:nshyL0/TEXjsN65zSciFRxbGvfU186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U082 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2504997|ensemblbacteria:AAL81841 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:if2g_pyrfu(display_long)|uniprotkb:eif2g(gene name)|psi-mi:eif2g(display_short)|uniprotkb:eIF-2-gamma(gene name synonym)|uniprotkb:aIF2-gamma(gene name synonym)|uniprotkb:PF1717(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81841(transcript)|ensemblbacteria:PF1717(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR022424|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:2D74|rcsb pdb:2DCU|refseq:WP_011012863.1|dip:DIP-54412N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:7itwOYEWX0x39YqvxRaCUaaoYjQ186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U1E4 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505216|ensemblbacteria:AAL81388 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:if5a_pyrfu(display_long)|uniprotkb:eif5a(gene name)|psi-mi:eif5a(display_short)|uniprotkb:eIF-5A(gene name synonym)|uniprotkb:Hypusine-containing protein(gene name synonym)|uniprotkb:PF1264(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81388(transcript)|ensemblbacteria:PF1264(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019769|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR022847|interpro:IPR020189|interpro:IPR013185(Translation elongation factor, KOW-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR008991(Translation protein SH3-like)|refseq:WP_011012408.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:o/VriQvHAlBCYMiAl4N+Vb659sI186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U0B4 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505061|ensemblbacteria:AAL81809 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:lysj_pyrfu(display_long)|uniprotkb:lysJ(gene name)|psi-mi:lysJ(display_short)|uniprotkb:PF1685(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81809(transcript)|ensemblbacteria:PF1685(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0008483"(transaminase activity)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042450"(arginine biosynthetic process via ornithine)|interpro:IPR004636(Acetylornithine and succinylornithine aminotransferase)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:WP_011012831.1|interpro:IPR037537 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:UKF9g2JJdGyfjD+zyO2uiUaHcgU186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U0B6 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505018|ensemblbacteria:AAL81807 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:lysy_pyrfu(display_long)|uniprotkb:lysY(gene name)|psi-mi:lysY(display_short)|uniprotkb:PF1683(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81807(transcript)|ensemblbacteria:PF1683(gene)|go:"GO:0003942"(N-acetyl-gamma-glutamyl-phosphate reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0042450"(arginine biosynthetic process via ornithine)|go:"GO:0043870"(N-acetyl-gamma-aminoadipyl-phosphate reductase activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051287"(NAD binding)|interpro:IPR023013|interpro:IPR000706(N-acetyl-gamma-glutamyl-phosphate reductase)|interpro:IPR000534(Semialdehyde dehydrogenase, NAD-binding)|interpro:IPR012280(Semialdehyde dehydrogenase, dimerisation region)|refseq:WP_011012829.1|interpro:IPR036291|interpro:IPR037535 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:/jafrQwCFKzEXawMRbWwQklWz8Y186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8TZL4 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505363|ensemblbacteria:AAL82100 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:nadb_pyrfu(display_long)|uniprotkb:nadB(gene name)|psi-mi:nadB(display_short)|uniprotkb:Quinolinate synthase B(gene name synonym)|uniprotkb:PF1976(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL82100(transcript)|ensemblbacteria:PF1976(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0008734"(L-aspartate oxidase activity)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0044318"("L-aspartate:fumarate oxidoreductase activity")|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR005288(L-aspartate oxidase)|refseq:WP_011013118.1|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:Ov5NDjjiQkWUvQJuqhJzyja/z04186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:E7FHX6 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505584|ensemblbacteria:AAL80564|uniprotkb:Q7LX09|uniprotkb:P95484 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:ndrz_pyrfu(display_long)|uniprotkb:rnr(gene name)|psi-mi:rnr(display_short)|uniprotkb:Ribonucleotide reductase(gene name synonym)|uniprotkb:PF0440(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL80564(transcript)|ensemblbacteria:PF0440(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0016539"(intein-mediated protein splicing)|go:"GO:0031419"(cobalamin binding)|interpro:IPR005144(ATP-cone)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR006142(Intein)|interpro:IPR004042(Intein DOD homing endonuclease)|interpro:IPR006141(Intein splicing site)|interpro:IPR015147(PI-PfuI intein endonuclease subregion)|interpro:IPR013344(Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR015146(Ribonucleotide reductase, stirrup)|rcsb pdb:1DQ3|interpro:IPR030934|refseq:WP_011011558.1|interpro:IPR027434|interpro:IPR004860(LAGLIDADG DNA endonuclease)|interpro:IPR036844 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:lD4HCNqaf9xVHqqF5R6DA+PWFEQ186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q51742 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505284|ensemblbacteria:AAL80718 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:otca_pyrfu(display_long)|uniprotkb:argF(gene name)|psi-mi:argF(display_short)|uniprotkb:PF0594(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL80718(transcript)|ensemblbacteria:PF0594(gene)|go:"GO:0004585"(ornithine carbamoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0016597"(amino acid binding)|interpro:IPR002292(Ornithine carbamoyltransferase)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR024904|interpro:IPR036901|rcsb pdb:1PVV|rcsb pdb:1A1S|refseq:WP_011011713.1|dip:DIP-48301N psi-mi:"MI:0469"(intact) - crc64:14404FBDC2ECCB95 figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:ieRzgP82qU7GKvlW1YdLxdmzjN8186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q51804 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505432|ensemblbacteria:AAL81090 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:pora_pyrfu(display_long)|uniprotkb:porA(gene name)|psi-mi:porA(display_short)|uniprotkb:Pyruvate oxidoreductase alpha chain(gene name synonym)|uniprotkb:Pyruvic-ferredoxin oxidoreductase subunit alpha(gene name synonym)|uniprotkb:PF0966(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81090(transcript)|ensemblbacteria:PF0966(gene)|go:"GO:0019164"(pyruvate synthase activity)|interpro:IPR033412|interpro:IPR029061|refseq:WP_011012103.1|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:ywWQhFQB5WivwgNR2j/qjrrgbWw186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8TZZ6 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505099|ensemblbacteria:AAL81951 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:q8tzz6_pyrfu(display_long)|uniprotkb:PF1827(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81951(transcript)|ensemblbacteria:PF1827(gene)|interpro:IPR000644(Cystathionine beta-synthase, core)|refseq:WP_011012968.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:nhE0fuGmMLcXEyMwf0h2g/S0z7k186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U049 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505566|ensemblbacteria:AAL81892 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:q8u049_pyrfu(display_long)|uniprotkb:PF1768(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81892(transcript)|ensemblbacteria:PF1768(gene)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR029061|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|refseq:WP_011012909.1|interpro:IPR033412 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:XiVByYCgl5N9/GMfAbopnuwNW4w186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U124 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505300|ensemblbacteria:AAL81529 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:q8u124_pyrfu(display_long)|uniprotkb:PF1405(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81529(transcript)|ensemblbacteria:PF1405(gene)|go:"GO:0003723"(RNA binding)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR022712|interpro:IPR019975|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR033769|interpro:IPR036866 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:TEt9RRzmXarJwNUy4MdkNAimL0c186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U1H0 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505246|ensemblbacteria:AAL81362 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:q8u1h0_pyrfu(display_long)|uniprotkb:PF1238(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81362(transcript)|ensemblbacteria:PF1238(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0008080"(N-acetyltransferase activity)|refseq:WP_011012381.1|interpro:IPR003439(ABC transporter-like)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:Ph2Tu7/KIEJr+iGLKx4846IPlHY186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U1K3 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505527|ensemblbacteria:AAL81327 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:q8u1k3_pyrfu(display_long)|uniprotkb:PF1203(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81327(transcript)|ensemblbacteria:PF1203(gene)|go:"GO:0009055"(electron transfer activity)|go:"GO:0033726"(aldehyde ferredoxin oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR013985(Aldehyde ferredoxin oxidoreductase, domain 3)|interpro:IPR013983(Aldehyde ferredoxin oxidoreductase, N-terminal)|interpro:IPR001203(Aldehyde ferredoxin oxidoreductase, C-terminal)|interpro:IPR013984(Aldehyde ferredoxin oxidoreductase, domain 2)|rcsb pdb:1B25|rcsb pdb:1B4N|interpro:IPR036021|interpro:IPR036503 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:W7Jcmwv3uRJGbS6mDIqjJFn30Ho186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U310 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505380|ensemblbacteria:AAL80790 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:q8u310_pyrfu(display_long)|uniprotkb:PF0666(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 go:"GO:0006396"(RNA processing)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|ensemblbacteria:AAL80790(transcript)|ensemblbacteria:PF0666(gene)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|interpro:IPR029063|interpro:IPR031341|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR011023(Nop2p)|interpro:IPR023267|refseq:WP_011011787.1|interpro:IPR035926 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:clWLMJaoFstA3m5xJcHSeaeT6YE186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U3C3 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505312|ensemblbacteria:AAL80671 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:q8u3c3_pyrfu(display_long)|uniprotkb:PF0547(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL80671(transcript)|ensemblbacteria:PF0547(gene)|refseq:WP_011011665.1|interpro:IPR003495("Cobalamin (vitamin B12) biosynthesis CobW-like")|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:soSL9PCM2Tl22ZzSWSLq+RzhKh8186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U3D5 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505450|ensemblbacteria:AAL80657 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:q8u3d5_pyrfu(display_long)|uniprotkb:Indolepyruvate ferredoxin oxidoreductase subunit alpha(gene name synonym)|uniprotkb:PF0533(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL80657(transcript)|ensemblbacteria:PF0533(gene)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0043805"(indolepyruvate ferredoxin oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR029061|refseq:WP_011011650.1|interpro:IPR017896|interpro:IPR017900|interpro:IPR017721(Indolepyruvate ferredoxin oxidoreductase, alpha subunit)|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:ZN7VOE+PE7DiDmkEYnDh3jWXYLM186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U3V4 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505241|ensemblbacteria:AAL80475 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:q8u3v4_pyrfu(display_long)|uniprotkb:PF0351(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL80475(transcript)|ensemblbacteria:PF0351(gene) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:M01abl5rQrT/7I8Xt9jHSqRHxRA186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U444 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505407|ensemblbacteria:AAL80375 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:q8u444_pyrfu(display_long)|uniprotkb:PF0251(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL80375(transcript)|ensemblbacteria:PF0251(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|interpro:IPR029063|interpro:IPR002478(PUA)|interpro:IPR015947(PUA-like)|interpro:IPR019614|refseq:WP_011011366.1|interpro:IPR036974|interpro:IPR041532 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:ETrXT0vZUx9ZeDIFBOieoDCl8E0186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U472 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505327|ensemblbacteria:AAL80344 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:q8u472_pyrfu(display_long)|uniprotkb:PF0220(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL80344(transcript)|ensemblbacteria:PF0220(gene)|go:"GO:0004590"(orotidine-5'-phosphate decarboxylase activity)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016853"(isomerase activity)|go:"GO:0019647"(formaldehyde assimilation via ribulose monophosphate cycle)|go:"GO:0043801"(hexulose-6-phosphate synthase activity)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:1901135"(carbohydrate derivative metabolic process)|interpro:IPR017553(3-hexulose-6-phosphate synthase)|interpro:IPR017552(6-phospho 3-hexuloisomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR001754(Orotidine 5'-phosphate decarboxylase, core)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR001347("Sugar isomerase (SIS)")|interpro:IPR041710 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:7QPSzJo8nBA4PFbcDNizidqC3IQ186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q9HGZ8 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505397|ensemblbacteria:AAL81870|uniprotkb:Q7LYC6 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:q9hgz8_pyrfu(display_long)|uniprotkb:PF1746(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81870(transcript)|ensemblbacteria:PF1746(gene)|go:"GO:0005975"(carbohydrate metabolic process)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR032790|interpro:IPR032856|interpro:IPR008928(Six-hairpin glycosidase-like)|refseq:WP_004068229.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:fT250nttrR305cvllDQx5DMsY9k186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:P95479 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505169|ensemblbacteria:AAL80619|uniprotkb:Q8U3H2 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:rgyr_pyrfu(display_long)|uniprotkb:rgy(gene name)|psi-mi:rgy(display_short)|uniprotkb:PF0495(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL80619(transcript)|ensemblbacteria:PF0495(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR005736(Reverse gyrase)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR023405|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|refseq:WP_011011612.1|interpro:IPR034142|interpro:IPR027417|interpro:IPR040569|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:VlL42YNi+cr5cv5sd5k/p9pp9QI186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U0H4 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505259|ensemblbacteria:AAL81739 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:rtcb_pyrfu(display_long)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym)|uniprotkb:PF1615(locus name)|uniprotkb:rtcB(gene name)|psi-mi:rtcB(display_short) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81739(transcript)|ensemblbacteria:PF1615(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0006314"(intron homing)|go:"GO:0008033"(tRNA processing)|go:"GO:0008452"(RNA ligase activity)|go:"GO:0016539"(intein-mediated protein splicing)|go:"GO:0046872"(metal ion binding)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR006142(Intein)|interpro:IPR004042(Intein DOD homing endonuclease)|interpro:IPR006141(Intein splicing site)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR030934|interpro:IPR027434|interpro:IPR004860(LAGLIDADG DNA endonuclease)|interpro:IPR036025|interpro:IPR036844 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:OnGptyQxtODMTZW1+4HXkrrxqKg186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8TZY2 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505615|ensemblbacteria:AAL81967|uniprotkb:Q877I1 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:smc_pyrfu(display_long)|uniprotkb:PF1843(locus name)|uniprotkb:smc(gene name)|psi-mi:smc(display_short) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81967(transcript)|ensemblbacteria:PF1843(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030261"(chromosome condensation)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR011890(Chromosome segregation protein SMC)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|rcsb pdb:1XEW|rcsb pdb:1XEX|rcsb pdb:3KTA|rcsb pdb:3NWC|rcsb pdb:4I99|rcsb pdb:4RSJ|rcsb pdb:5XNS|refseq:WP_014835559.1|dip:DIP-54374N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:UbFlPWGY1xYWu8wr4f1MrD09sHE186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U261 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505119|ensemblbacteria:AAL81113 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:syfa_pyrfu(display_long)|uniprotkb:pheS(gene name)|psi-mi:pheS(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)|uniprotkb:PF0989(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81113(transcript)|ensemblbacteria:PF0989(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR022917|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|refseq:WP_011012126.1|interpro:IPR036388|interpro:IPR036390 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:UVh+d5UQWlnf+ZgyOeUkBdfczlU186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U260 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505044|ensemblbacteria:AAL81114 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:syfb_pyrfu(display_long)|uniprotkb:pheT(gene name)|psi-mi:pheT(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:PF0990(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81114(transcript)|ensemblbacteria:PF0990(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|interpro:IPR009061(Putative DNA binding)|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR022918|interpro:IPR005147(tRNA synthetase, B5)|interpro:IPR005146(B3/B4 tRNA-binding domain)|refseq:WP_011012127.1|interpro:IPR020825|interpro:IPR041616 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:PNG8co3gGlQ+iZ1CsC55Qk40ZY8186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U1K2 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505197|ensemblbacteria:AAL81328 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:sys_pyrfu(display_long)|uniprotkb:serS(gene name)|psi-mi:serS(display_short)|uniprotkb:"Seryl-tRNA(Ser/Sec) synthetase"(gene name synonym)|uniprotkb:PF1204(locus name)|uniprotkb:Seryl-tRNA synthetase(gene name synonym) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81328(transcript)|ensemblbacteria:PF1204(gene)|go:"GO:0004828"(serine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006434"(seryl-tRNA aminoacylation)|go:"GO:0016260"(selenocysteine biosynthetic process)|go:"GO:0097056"("selenocysteinyl-tRNA(Sec) biosynthetic process")|interpro:IPR033729|refseq:WP_011012345.1|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002317(Seryl-tRNA synthetase, class IIa)|interpro:IPR015866(Seryl-tRNA synthetase, class IIa, N-terminal)|interpro:IPR010978(tRNA-binding arm)|interpro:IPR042103 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:Gdl5Kibb4Mupdyh1jNh/sbdWJ7A186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U4G4 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505135|ensemblbacteria:AAL80248 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:tmbl1_pyrfu(display_long)|uniprotkb:trmBL1(gene name)|psi-mi:trmBL1(display_short)|uniprotkb:PF0124(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL80248(transcript)|ensemblbacteria:PF0124(gene)|go:"GO:0003677"(DNA binding)|interpro:IPR021586|interpro:IPR002831(Transcriptional regulator TrmB)|refseq:WP_011011236.1|interpro:IPR036388|interpro:IPR036390 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:dQfXNCK6MKfl8cQekBSpdfDYuiU186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U3H1 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505278|ensemblbacteria:AAL80620 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:tmbl2_pyrfu(display_long)|uniprotkb:trmBL2(gene name)|psi-mi:trmBL2(display_short)|uniprotkb:PF0496(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL80620(transcript)|ensemblbacteria:PF0496(gene)|go:"GO:0003677"(DNA binding)|rcsb pdb:5BOX|rcsb pdb:5BPD|rcsb pdb:5BPI|rcsb pdb:5BQT|refseq:WP_011011613.1|interpro:IPR021586|interpro:IPR002831(Transcriptional regulator TrmB)|interpro:IPR036388|interpro:IPR036390 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:37tJg6l1rZVFP2TznsYggbKuGUQ186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U0K9 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505468|ensemblbacteria:AAL81702 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:top6a_pyrfu(display_long)|uniprotkb:top6A(gene name)|psi-mi:top6A(display_short)|uniprotkb:Type II DNA topoisomerase VI subunit A(gene name synonym)|uniprotkb:PF1578(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|ensemblbacteria:AAL81702(transcript)|ensemblbacteria:PF1578(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR004085(DNA topoisomerase VI, subunit A)|refseq:WP_011012724.1|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:ieUihkvEU9gZZnlVRoAcmYL6zL0186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q8U0K8 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2505415|ensemblbacteria:AAL81703 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:top6b_pyrfu(display_long)|uniprotkb:top6B(gene name)|psi-mi:top6B(display_short)|uniprotkb:Type II DNA topoisomerase VI subunit B(gene name synonym)|uniprotkb:PF1579(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81703(transcript)|ensemblbacteria:PF1579(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR005734(DNA topoisomerase VI, subunit B)|interpro:IPR015320(DNA topoisomerase VI, subunit B, transducer)|refseq:WP_011012725.1|interpro:IPR036890 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:ceCQtb+tOmpxgyTxGNe4Uny8+UA186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:E7FI45 uniprotkb:Q51801 intact:EBI-2507144|ensemblbacteria:AAL81664|uniprotkb:Q7LWY1|uniprotkb:Q9Y8L1 intact:EBI-2507011|ensemblbacteria:AAL81093 psi-mi:acda1_pyrfu(display_long)|uniprotkb:acdAI(gene name)|psi-mi:acdAI(display_short)|uniprotkb:ADP-forming acetyl coenzyme A synthetase I subunit alpha(gene name synonym)|uniprotkb:PF1540(locus name) psi-mi:vora_pyrfu(display_long)|uniprotkb:vorA(gene name)|psi-mi:vorA(display_short)|uniprotkb:2-oxoisovalerate oxidoreductase alpha chain(gene name synonym)|uniprotkb:2-oxoisovalerate ferredoxin reductase subunit alpha(gene name synonym)|uniprotkb:PF0969(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2504970|imex:IM-12113-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81664(transcript)|ensemblbacteria:PF1540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0043758"("acetate-CoA ligase (ADP-forming) activity")|go:"GO:0005737"(cytoplasm)|refseq:WP_011012687.1|interpro:IPR032875|interpro:IPR014089("Acetyl coenzyme A synthetase (ADP forming), alpha domain")|interpro:IPR003781(CoA-binding)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR036291|interpro:IPR043938 ensemblbacteria:AAL81093(transcript)|ensemblbacteria:PF0969(gene)|go:"GO:0043807"("3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity")|interpro:IPR029061|refseq:WP_011012106.1|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E, Supp. Table 1|comment:"A number of prokaryotic silencing (psi)RNAs were purified with this complex"|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:VLb2yQEWTPue1LA75XOEkpc3loU186497 rogid:Qn9YT5970JZEyrujyR7J6r3EfMM186497 intact-crc:B099FA40C24BC9D1|rigid:WBF+qk6H7dUchcknA6txa+O8zFM false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q8U1S5 uniprotkb:Q8U1S6 intact:EBI-2504983|ensemblbacteria:AAL81254 intact:EBI-2504936|ensemblbacteria:AAL81253 psi-mi:cmr1a_pyrfu(display_long)|uniprotkb:cmr1-1(gene name)|psi-mi:cmr1-1(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr1-1(gene name synonym)|uniprotkb:PF1130(locus name) psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name) psi-mi:"MI:0920"(ribonuclease assay) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0902"(rna cleavage) psi-mi:"MI:0469"(IntAct) intact:EBI-2507266|imex:IM-12113-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81254(transcript)|ensemblbacteria:PF1130(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR007522(CRISPR-associated protein TM1795 family, N-terminal)|rcsb pdb:4W8X|rcsb pdb:4W8Z|refseq:WP_011012270.1|dip:DIP-54364N ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N go:"GO:0034661"(ncRNA catabolic process) - - caution:It is unclear which of the subunits has catalytic activity so the biological role 'enzyme' could not be assigned.|figure legend:5A|comment:psiRNA cleaved at 2 sites to generate 14- and 20-nucleotide 5′ end-labeled products.|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/02 2014/10/16 rogid:SxmHMZkKYv1zvzBsZcLpo3pdqss186497 rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497 intact-crc:4842F40DD2A94DEF false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8U1S5 uniprotkb:Q8U1S7 intact:EBI-2504983|ensemblbacteria:AAL81254 intact:EBI-2504943|ensemblbacteria:AAL81252 psi-mi:cmr1a_pyrfu(display_long)|uniprotkb:cmr1-1(gene name)|psi-mi:cmr1-1(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr1-1(gene name synonym)|uniprotkb:PF1130(locus name) psi-mi:cmr3_pyrfu(display_long)|uniprotkb:cmr3(gene name)|psi-mi:cmr3(display_short)|uniprotkb:CRISPR type III-B/RAMP module-associated protein Cmr3(gene name synonym)|uniprotkb:PF1128(locus name) psi-mi:"MI:0920"(ribonuclease assay) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0902"(rna cleavage) psi-mi:"MI:0469"(IntAct) intact:EBI-2507266|imex:IM-12113-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81254(transcript)|ensemblbacteria:PF1130(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR007522(CRISPR-associated protein TM1795 family, N-terminal)|rcsb pdb:4W8X|rcsb pdb:4W8Z|refseq:WP_011012270.1|dip:DIP-54364N ensemblbacteria:PF1128(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR010165(CRISPR-associated protein, TM1793)|interpro:IPR019117|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4H4K|ensemblbacteria:AAL81252(transcript)|refseq:WP_011012268.1|dip:DIP-54365N go:"GO:0034661"(ncRNA catabolic process) - - caution:It is unclear which of the subunits has catalytic activity so the biological role 'enzyme' could not be assigned.|figure legend:5A|comment:psiRNA cleaved at 2 sites to generate 14- and 20-nucleotide 5′ end-labeled products.|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/02 2014/10/16 rogid:SxmHMZkKYv1zvzBsZcLpo3pdqss186497 rogid:vxqihIKFjSErsbCL6/OiH04DOlY186497 intact-crc:4842F40DD2A94DEF false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8U1S5 uniprotkb:Q8U1S9 intact:EBI-2504983|ensemblbacteria:AAL81254 intact:EBI-2504950|ensemblbacteria:AAL81250 psi-mi:cmr1a_pyrfu(display_long)|uniprotkb:cmr1-1(gene name)|psi-mi:cmr1-1(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr1-1(gene name synonym)|uniprotkb:PF1130(locus name) psi-mi:cmr4_pyrfu(display_long)|uniprotkb:cmr4(gene name)|psi-mi:cmr4(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr4(gene name synonym)|uniprotkb:Target RNase Cmr4(gene name synonym)|uniprotkb:PF1126(locus name) psi-mi:"MI:0920"(ribonuclease assay) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0902"(rna cleavage) psi-mi:"MI:0469"(IntAct) intact:EBI-2507266|imex:IM-12113-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81254(transcript)|ensemblbacteria:PF1130(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR007522(CRISPR-associated protein TM1795 family, N-terminal)|rcsb pdb:4W8X|rcsb pdb:4W8Z|refseq:WP_011012270.1|dip:DIP-54364N ensemblbacteria:AAL81250(transcript)|ensemblbacteria:PF1126(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR013410(CRISPR-associated RAMP Cmr4)|rcsb pdb:4RDP|rcsb pdb:4W8W|rcsb pdb:4WNZ|refseq:WP_011012266.1|dip:DIP-54367N go:"GO:0034661"(ncRNA catabolic process) - - caution:It is unclear which of the subunits has catalytic activity so the biological role 'enzyme' could not be assigned.|figure legend:5A|comment:psiRNA cleaved at 2 sites to generate 14- and 20-nucleotide 5′ end-labeled products.|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/02 2014/10/16 rogid:SxmHMZkKYv1zvzBsZcLpo3pdqss186497 rogid:Nm72GeycBUn1mj6QxSAdnMFsszA186497 intact-crc:4842F40DD2A94DEF false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8U1S5 uniprotkb:Q8U1T0 intact:EBI-2504983|ensemblbacteria:AAL81254 intact:EBI-2504964|ensemblbacteria:AAL81249 psi-mi:cmr1a_pyrfu(display_long)|uniprotkb:cmr1-1(gene name)|psi-mi:cmr1-1(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr1-1(gene name synonym)|uniprotkb:PF1130(locus name) psi-mi:cmr5_pyrfu(display_long)|uniprotkb:cmr5(gene name)|psi-mi:cmr5(display_short)|uniprotkb:CRISPR type III-B/RAMP module-associated protein Cmr5(gene name synonym)|uniprotkb:PF1125(locus name) psi-mi:"MI:0920"(ribonuclease assay) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0902"(rna cleavage) psi-mi:"MI:0469"(IntAct) intact:EBI-2507266|imex:IM-12113-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81254(transcript)|ensemblbacteria:PF1130(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR007522(CRISPR-associated protein TM1795 family, N-terminal)|rcsb pdb:4W8X|rcsb pdb:4W8Z|refseq:WP_011012270.1|dip:DIP-54364N ensemblbacteria:AAL81249(transcript)|ensemblbacteria:PF1125(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR010160(CRISPR-associated protein, TM1791.1)|interpro:IPR023101|rcsb pdb:4GKF|refseq:WP_011012265.1|dip:DIP-54369N go:"GO:0034661"(ncRNA catabolic process) - - caution:It is unclear which of the subunits has catalytic activity so the biological role 'enzyme' could not be assigned.|figure legend:5A|comment:psiRNA cleaved at 2 sites to generate 14- and 20-nucleotide 5′ end-labeled products.|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/02 2014/10/16 rogid:SxmHMZkKYv1zvzBsZcLpo3pdqss186497 rogid:vy8RHUFrrtBu6msl3Scl3awQtmM186497 intact-crc:4842F40DD2A94DEF false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8U1S5 uniprotkb:Q8U1T1 intact:EBI-2504983|ensemblbacteria:AAL81254 intact:EBI-2504957|ensemblbacteria:AAL81248 psi-mi:cmr1a_pyrfu(display_long)|uniprotkb:cmr1-1(gene name)|psi-mi:cmr1-1(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr1-1(gene name synonym)|uniprotkb:PF1130(locus name) psi-mi:cmr6_pyrfu(display_long)|uniprotkb:cmr6(gene name)|psi-mi:cmr6(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr6(gene name synonym)|uniprotkb:PF1124(locus name) psi-mi:"MI:0920"(ribonuclease assay) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0902"(rna cleavage) psi-mi:"MI:0469"(IntAct) intact:EBI-2507266|imex:IM-12113-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81254(transcript)|ensemblbacteria:PF1130(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR007522(CRISPR-associated protein TM1795 family, N-terminal)|rcsb pdb:4W8X|rcsb pdb:4W8Z|refseq:WP_011012270.1|dip:DIP-54364N ensemblbacteria:AAL81248(transcript)|ensemblbacteria:PF1124(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR010172(CRISPR-associated protein, TM1791)|rcsb pdb:4W8V|refseq:WP_011012264.1|dip:DIP-54368N go:"GO:0034661"(ncRNA catabolic process) - - caution:It is unclear which of the subunits has catalytic activity so the biological role 'enzyme' could not be assigned.|figure legend:5A|comment:psiRNA cleaved at 2 sites to generate 14- and 20-nucleotide 5′ end-labeled products.|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/02 2014/10/16 rogid:SxmHMZkKYv1zvzBsZcLpo3pdqss186497 rogid:puSz7Udnj8h4VthO+EkLW7njqN0186497 intact-crc:4842F40DD2A94DEF false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8U1S5 intact:EBI-2507257 intact:EBI-2504983|ensemblbacteria:AAL81254 - psi-mi:cmr1a_pyrfu(display_long)|uniprotkb:cmr1-1(gene name)|psi-mi:cmr1-1(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr1-1(gene name synonym)|uniprotkb:PF1130(locus name) psi-mi:psirna701(display_short)|psi-mi:EBI-2507257(display_long) psi-mi:"MI:0920"(ribonuclease assay) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0902"(rna cleavage) psi-mi:"MI:0469"(IntAct) intact:EBI-2507266|imex:IM-12113-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0320"(ribonucleic acid) ensemblbacteria:AAL81254(transcript)|ensemblbacteria:PF1130(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR007522(CRISPR-associated protein TM1795 family, N-terminal)|rcsb pdb:4W8X|rcsb pdb:4W8Z|refseq:WP_011012270.1|dip:DIP-54364N pubmed:19945378(see-also) go:"GO:0034661"(ncRNA catabolic process) - - caution:It is unclear which of the subunits has catalytic activity so the biological role 'enzyme' could not be assigned.|figure legend:5A|comment:psiRNA cleaved at 2 sites to generate 14- and 20-nucleotide 5′ end-labeled products.|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/02 2014/10/16 rogid:SxmHMZkKYv1zvzBsZcLpo3pdqss186497 crc64:72FA9B02A267B6E5 intact-crc:4842F40DD2A94DEF false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8U1S6 uniprotkb:Q8U1S7 intact:EBI-2504936|ensemblbacteria:AAL81253 intact:EBI-2504943|ensemblbacteria:AAL81252 psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name) psi-mi:cmr3_pyrfu(display_long)|uniprotkb:cmr3(gene name)|psi-mi:cmr3(display_short)|uniprotkb:CRISPR type III-B/RAMP module-associated protein Cmr3(gene name synonym)|uniprotkb:PF1128(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2507294|imex:IM-12113-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N ensemblbacteria:PF1128(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR010165(CRISPR-associated protein, TM1793)|interpro:IPR019117|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4H4K|ensemblbacteria:AAL81252(transcript)|refseq:WP_011012268.1|dip:DIP-54365N psi-mi:"MI:0469"(intact) - - figure legend:Supp. Table 1|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497 rogid:vxqihIKFjSErsbCL6/OiH04DOlY186497 intact-crc:7A19CBAE98D61480|rigid:GO2rZjc5yVAhwKpL4h3ZRaVvghc false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q8U1S6 uniprotkb:Q8U1S9 intact:EBI-2504936|ensemblbacteria:AAL81253 intact:EBI-2504950|ensemblbacteria:AAL81250 psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name) psi-mi:cmr4_pyrfu(display_long)|uniprotkb:cmr4(gene name)|psi-mi:cmr4(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr4(gene name synonym)|uniprotkb:Target RNase Cmr4(gene name synonym)|uniprotkb:PF1126(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2507294|imex:IM-12113-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N ensemblbacteria:AAL81250(transcript)|ensemblbacteria:PF1126(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR013410(CRISPR-associated RAMP Cmr4)|rcsb pdb:4RDP|rcsb pdb:4W8W|rcsb pdb:4WNZ|refseq:WP_011012266.1|dip:DIP-54367N psi-mi:"MI:0469"(intact) - - figure legend:Supp. Table 1|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497 rogid:Nm72GeycBUn1mj6QxSAdnMFsszA186497 intact-crc:7A19CBAE98D61480|rigid:GO2rZjc5yVAhwKpL4h3ZRaVvghc false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q8U1S6 uniprotkb:Q8U1T1 intact:EBI-2504936|ensemblbacteria:AAL81253 intact:EBI-2504957|ensemblbacteria:AAL81248 psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name) psi-mi:cmr6_pyrfu(display_long)|uniprotkb:cmr6(gene name)|psi-mi:cmr6(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr6(gene name synonym)|uniprotkb:PF1124(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2507294|imex:IM-12113-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N ensemblbacteria:AAL81248(transcript)|ensemblbacteria:PF1124(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR010172(CRISPR-associated protein, TM1791)|rcsb pdb:4W8V|refseq:WP_011012264.1|dip:DIP-54368N psi-mi:"MI:0469"(intact) - - figure legend:Supp. Table 1|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497 rogid:puSz7Udnj8h4VthO+EkLW7njqN0186497 intact-crc:7A19CBAE98D61480|rigid:GO2rZjc5yVAhwKpL4h3ZRaVvghc false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q8U1S6 uniprotkb:Q8TZZ6 intact:EBI-2504936|ensemblbacteria:AAL81253 intact:EBI-2505099|ensemblbacteria:AAL81951 psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name) psi-mi:q8tzz6_pyrfu(display_long)|uniprotkb:PF1827(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2507294|imex:IM-12113-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N ensemblbacteria:AAL81951(transcript)|ensemblbacteria:PF1827(gene)|interpro:IPR000644(Cystathionine beta-synthase, core)|refseq:WP_011012968.1 psi-mi:"MI:0469"(intact) - - figure legend:Supp. Table 1|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497 rogid:nhE0fuGmMLcXEyMwf0h2g/S0z7k186497 intact-crc:7A19CBAE98D61480|rigid:GO2rZjc5yVAhwKpL4h3ZRaVvghc false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q8U1S6 uniprotkb:Q8U0N8 intact:EBI-2504936|ensemblbacteria:AAL81253 intact:EBI-2505647|ensemblbacteria:AAL81672 psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name) psi-mi:q8u0n8_pyrfu(display_long)|uniprotkb:PF1548(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2507294|imex:IM-12113-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N ensemblbacteria:AAL81672(transcript)|ensemblbacteria:PF1548(gene)|refseq:WP_011012695.1 psi-mi:"MI:0469"(intact) - - figure legend:Supp. Table 1|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497 rogid:q8o2W6G8YsnJ8AArXaKnGyRYm14186497 intact-crc:7A19CBAE98D61480|rigid:GO2rZjc5yVAhwKpL4h3ZRaVvghc false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q8U1S6 uniprotkb:Q8U1G3 intact:EBI-2504936|ensemblbacteria:AAL81253 intact:EBI-2505697|ensemblbacteria:AAL81369 psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name) psi-mi:q8u1g3_pyrfu(display_long)|uniprotkb:PF1245(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2507294|imex:IM-12113-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N ensemblbacteria:AAL81369(transcript)|ensemblbacteria:PF1245(gene)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR023753|interpro:IPR042204|interpro:IPR036188|interpro:IPR041117|interpro:IPR041854 psi-mi:"MI:0469"(intact) - - figure legend:Supp. Table 1|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497 rogid:/YBZKJJk2a7yHuNChgrTrPERdt0186497 intact-crc:7A19CBAE98D61480|rigid:GO2rZjc5yVAhwKpL4h3ZRaVvghc false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q8U1S6 uniprotkb:Q8U487 intact:EBI-2504936|ensemblbacteria:AAL81253 intact:EBI-2505672|ensemblbacteria:AAL80328 psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name) psi-mi:q8u487_pyrfu(display_long)|uniprotkb:PF0204(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2507294|imex:IM-12113-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N ensemblbacteria:AAL80328(transcript)|ensemblbacteria:PF0204(gene)|interpro:IPR029055|interpro:IPR017932|interpro:IPR012375(Glutamate synthase, large subunit region 1 amidotransferase, putative)|refseq:WP_011011317.1 psi-mi:"MI:0469"(intact) - - figure legend:Supp. Table 1|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497 rogid:JFDzDDZKuhqNiAOhHydf2v/m7i0186497 intact-crc:7A19CBAE98D61480|rigid:GO2rZjc5yVAhwKpL4h3ZRaVvghc false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q8U1S6 uniprotkb:Q8U4C6 intact:EBI-2504936|ensemblbacteria:AAL81253 intact:EBI-2505666|ensemblbacteria:AAL80286 psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name) psi-mi:q8u4c6_pyrfu(display_long)|uniprotkb:PF0162(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2507294|imex:IM-12113-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N ensemblbacteria:AAL80286(transcript)|ensemblbacteria:PF0162(gene)|interpro:IPR005489(Protein of unknown function DUF257)|refseq:WP_011011275.1 psi-mi:"MI:0469"(intact) - - figure legend:Supp. Table 1|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497 rogid:acvAosf7U8Bt7Ew4hxxAihpWMC8186497 intact-crc:7A19CBAE98D61480|rigid:GO2rZjc5yVAhwKpL4h3ZRaVvghc false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q8U1S6 uniprotkb:Q8U4I5 intact:EBI-2504936|ensemblbacteria:AAL81253 intact:EBI-2505628|ensemblbacteria:AAL80226 psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name) psi-mi:q8u4i5_pyrfu(display_long)|uniprotkb:PF0102(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2507294|imex:IM-12113-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N ensemblbacteria:AAL80226(transcript)|ensemblbacteria:PF0102(gene)|go:"GO:0005524"(ATP binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR010624(Circadian clock protein KaiC)|refseq:WP_011011214.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - figure legend:Supp. Table 1|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497 rogid:dEDKsFTa8VNHlwHUFj+81DuqBbM186497 intact-crc:7A19CBAE98D61480|rigid:GO2rZjc5yVAhwKpL4h3ZRaVvghc false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q8U1S6 uniprotkb:Q9P9K5 intact:EBI-2504936|ensemblbacteria:AAL81253 intact:EBI-2505638|uniprotkb:Q7LWX3 psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name) psi-mi:q9p9k5_9eury(display_long) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:2261(9eury)|taxid:2261(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2507294|imex:IM-12113-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|refseq:WP_011013022.1|interpro:IPR031107|interpro:IPR007052(CS domain) psi-mi:"MI:0469"(intact) - - figure legend:Supp. Table 1|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497 rogid:7NdWcXZUIv93fusPL8Q2hbVn0842261 intact-crc:7A19CBAE98D61480|rigid:GO2rZjc5yVAhwKpL4h3ZRaVvghc false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q8U1S6 uniprotkb:P58301 intact:EBI-2504936|ensemblbacteria:AAL81253 intact:EBI-2505704|ensemblbacteria:AAL81291 psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name) psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2507294|imex:IM-12113-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N psi-mi:"MI:0469"(intact) - - figure legend:Supp. Table 1|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497 rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497 intact-crc:7A19CBAE98D61480|rigid:GO2rZjc5yVAhwKpL4h3ZRaVvghc false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q8U1S6 uniprotkb:Q8TZY2 intact:EBI-2504936|ensemblbacteria:AAL81253 intact:EBI-2505615|ensemblbacteria:AAL81967|uniprotkb:Q877I1 psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name) psi-mi:smc_pyrfu(display_long)|uniprotkb:PF1843(locus name)|uniprotkb:smc(gene name)|psi-mi:smc(display_short) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2507294|imex:IM-12113-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N ensemblbacteria:AAL81967(transcript)|ensemblbacteria:PF1843(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030261"(chromosome condensation)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR011890(Chromosome segregation protein SMC)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|rcsb pdb:1XEW|rcsb pdb:1XEX|rcsb pdb:3KTA|rcsb pdb:3NWC|rcsb pdb:4I99|rcsb pdb:4RSJ|rcsb pdb:5XNS|refseq:WP_014835559.1|dip:DIP-54374N psi-mi:"MI:0469"(intact) - - figure legend:Supp. Table 1|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497 rogid:UbFlPWGY1xYWu8wr4f1MrD09sHE186497 intact-crc:7A19CBAE98D61480|rigid:GO2rZjc5yVAhwKpL4h3ZRaVvghc false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q8U1S6 uniprotkb:P81554 intact:EBI-2504936|ensemblbacteria:AAL81253 intact:EBI-2505681|ensemblbacteria:AAL81995 psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name) psi-mi:trm1_pyrfu(display_long)|uniprotkb:trm1(gene name)|psi-mi:trm1(display_short)|uniprotkb:"tRNA(guanine-26,N(2)-N(2)) methyltransferase"(gene name synonym)|uniprotkb:tRNA 2,2-dimethylguanosine-26 methyltransferase(gene name synonym)|uniprotkb:"tRNA(m(2,2)G26)dimethyltransferase"(gene name synonym)|uniprotkb:PF1871(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2507294|imex:IM-12113-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N ensemblbacteria:AAL81995(transcript)|ensemblbacteria:PF1871(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004809"("tRNA (guanine-N2-)-methyltransferase activity")|interpro:IPR029063|interpro:IPR022923|interpro:IPR002905(N2,N2-dimethylguanosine tRNA methyltransferase)|interpro:IPR042296 psi-mi:"MI:0469"(intact) - - figure legend:Supp. Table 1|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497 rogid:Qzts27oTZAcKM1iA/zsE2zSKXnU186497 intact-crc:7A19CBAE98D61480|rigid:GO2rZjc5yVAhwKpL4h3ZRaVvghc false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q8U1S6 uniprotkb:Q8TZQ5 intact:EBI-2504936|ensemblbacteria:AAL81253 intact:EBI-2505652|ensemblbacteria:AAL82055 psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name) psi-mi:y1931_pyrfu(display_long)|uniprotkb:PF1931(locus name) psi-mi:"MI:0091"(chromatography technology) Hale et al. (2009) imex:IM-12113|pubmed:19945378 taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2507294|imex:IM-12113-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N ensemblbacteria:AAL82055(transcript)|go:"GO:0005524"(ATP binding)|ensemblbacteria:PF1931(gene)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR022475|refseq:WP_011013071.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - figure legend:Supp. Table 1|dataset:Archaea - Interaction dataset based on Archaea proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus) - 2009/12/02 2014/10/16 rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497 rogid:cGViNm1T2p+fZcyxAHtrdGmTLzY186497 intact-crc:7A19CBAE98D61480|rigid:GO2rZjc5yVAhwKpL4h3ZRaVvghc false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)