#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P25588	uniprotkb:Q08496	intact:EBI-412442|uniprotkb:P25589|uniprotkb:P27513|uniprotkb:P87003|uniprotkb:Q07218|uniprotkb:Q8NIN2|uniprotkb:D6VQV6|ensemblfungi:YCL061C	intact:EBI-31943|uniprotkb:O00034|uniprotkb:Q7LGN4|uniprotkb:D6W2E3|ensemblfungi:YOR080W	psi-mi:mrc1_yeast(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:YCL061C(locus name)|uniprotkb:YCL61C/YCL60C(orf name)|uniprotkb:DNA replication checkpoint mediator MRC1(gene name synonym)	psi-mi:dia2_yeast(display_long)|uniprotkb:Digs into agar protein 2(gene name synonym)|uniprotkb:DIA2(gene name)|psi-mi:DIA2(display_short)|uniprotkb:YOR29-31(orf name)|uniprotkb:YOR080W(locus name)	psi-mi:"MI:0018"(two hybrid)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594387|mint:MINT-7433915|imex:IM-13898-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009871.2|sgd:S000000566|ensemblfungi:YCL061C(gene)|ensemblfungi:YCL061C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|interpro:IPR018564|go:"GO:0000723"(telomere maintenance)|mint:P25588|dip:DIP-1017N|mint:MINT-7433919(identity)	refseq:NP_014723.2|sgd:S000005606|dip:DIP-6496N|mint:Q08496|ensemblfungi:YOR080W(gene)|ensemblfungi:YOR080W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043624"|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032675|interpro:IPR036047|mint:MINT-7433917(identity)	-	crc64:378345EE503FFA81	crc64:98B610994BA2F803	figure legend:f1a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/12/29	2014/10/16	rogid:Sv9pZwka0vVslquPGLQ2N/R7W/w559292	rogid:/hUI8VOftN8vuZMVkGk/6c0Zj2I559292	intact-crc:ABF5C36BC5E1F3BD|rigid:cepHbOfaV3JWwm4q1Aou1ywu7PE	false	fusion protein:?-?(MINT-7556220)	mutation increasing interaction:210-249(MINT-7556156)|fusion protein:?-?(MINT-7556225)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08496	uniprotkb:P25588	intact:EBI-31943|uniprotkb:O00034|uniprotkb:Q7LGN4|uniprotkb:D6W2E3|ensemblfungi:YOR080W	intact:EBI-412442|uniprotkb:P25589|uniprotkb:P27513|uniprotkb:P87003|uniprotkb:Q07218|uniprotkb:Q8NIN2|uniprotkb:D6VQV6|ensemblfungi:YCL061C	psi-mi:dia2_yeast(display_long)|uniprotkb:Digs into agar protein 2(gene name synonym)|uniprotkb:DIA2(gene name)|psi-mi:DIA2(display_short)|uniprotkb:YOR29-31(orf name)|uniprotkb:YOR080W(locus name)	psi-mi:mrc1_yeast(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:YCL061C(locus name)|uniprotkb:YCL61C/YCL60C(orf name)|uniprotkb:DNA replication checkpoint mediator MRC1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594444|mint:MINT-7500976|imex:IM-13898-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014723.2|sgd:S000005606|dip:DIP-6496N|mint:Q08496|ensemblfungi:YOR080W(gene)|ensemblfungi:YOR080W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043624"|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032675|interpro:IPR036047|mint:MINT-7500984(identity)	refseq:NP_009871.2|sgd:S000000566|ensemblfungi:YCL061C(gene)|ensemblfungi:YCL061C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|interpro:IPR018564|go:"GO:0000723"(telomere maintenance)|mint:P25588|dip:DIP-1017N|mint:MINT-7500982(identity)	-	crc64:98B610994BA2F803	crc64:378345EE503FFA81	figure legend:f1b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/12/29	2014/10/16	rogid:/hUI8VOftN8vuZMVkGk/6c0Zj2I559292	rogid:Sv9pZwka0vVslquPGLQ2N/R7W/w559292	intact-crc:09F0029597A3CE54|rigid:cepHbOfaV3JWwm4q1Aou1ywu7PE	false	mutation decreasing interaction:210-249(MINT-7556186)|fusion protein:?-?(MINT-7556228)	fusion protein:?-?(MINT-7556231)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25588	uniprotkb:Q08496	intact:EBI-412442|uniprotkb:P25589|uniprotkb:P27513|uniprotkb:P87003|uniprotkb:Q07218|uniprotkb:Q8NIN2|uniprotkb:D6VQV6|ensemblfungi:YCL061C	intact:EBI-31943|uniprotkb:O00034|uniprotkb:Q7LGN4|uniprotkb:D6W2E3|ensemblfungi:YOR080W	psi-mi:mrc1_yeast(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:YCL061C(locus name)|uniprotkb:YCL61C/YCL60C(orf name)|uniprotkb:DNA replication checkpoint mediator MRC1(gene name synonym)	psi-mi:dia2_yeast(display_long)|uniprotkb:Digs into agar protein 2(gene name synonym)|uniprotkb:DIA2(gene name)|psi-mi:DIA2(display_short)|uniprotkb:YOR29-31(orf name)|uniprotkb:YOR080W(locus name)	psi-mi:"MI:0018"(two hybrid)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594482|mint:MINT-7542423|imex:IM-13898-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009871.2|sgd:S000000566|ensemblfungi:YCL061C(gene)|ensemblfungi:YCL061C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|interpro:IPR018564|go:"GO:0000723"(telomere maintenance)|mint:P25588|dip:DIP-1017N|mint:MINT-7542432(identity)	refseq:NP_014723.2|sgd:S000005606|dip:DIP-6496N|mint:Q08496|ensemblfungi:YOR080W(gene)|ensemblfungi:YOR080W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043624"|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032675|interpro:IPR036047|mint:MINT-7542427(identity)	-	crc64:378345EE503FFA81	crc64:98B610994BA2F803	figure legend:f2a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/12/29	2014/10/16	rogid:Sv9pZwka0vVslquPGLQ2N/R7W/w559292	rogid:/hUI8VOftN8vuZMVkGk/6c0Zj2I559292	intact-crc:55977C3C6D2EE48C|rigid:cepHbOfaV3JWwm4q1Aou1ywu7PE	false	-	binding-associated region:?-?(MINT-7542428)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01454	uniprotkb:Q08496	intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W	intact:EBI-31943|uniprotkb:O00034|uniprotkb:Q7LGN4|uniprotkb:D6W2E3|ensemblfungi:YOR080W	psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym)	psi-mi:dia2_yeast(display_long)|uniprotkb:Digs into agar protein 2(gene name synonym)|uniprotkb:DIA2(gene name)|psi-mi:DIA2(display_short)|uniprotkb:YOR29-31(orf name)|uniprotkb:YOR080W(locus name)	psi-mi:"MI:0018"(two hybrid)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594465|mint:MINT-7542407|imex:IM-13898-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|mint:MINT-7542410(identity)	refseq:NP_014723.2|sgd:S000005606|dip:DIP-6496N|mint:Q08496|ensemblfungi:YOR080W(gene)|ensemblfungi:YOR080W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043624"|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032675|interpro:IPR036047|mint:MINT-7542409(identity)	-	crc64:E2ABBB244B5F8B4D	crc64:98B610994BA2F803	figure legend:f2a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/12/29	2014/10/16	rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292	rogid:/hUI8VOftN8vuZMVkGk/6c0Zj2I559292	intact-crc:9B92F474CBC6CA16|rigid:So4QBDmxqe1+l8/HkoKdVkIWX80	false	-	binding-associated region:?-?(MINT-7542417)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08496	uniprotkb:P25588	intact:EBI-31943|uniprotkb:O00034|uniprotkb:Q7LGN4|uniprotkb:D6W2E3|ensemblfungi:YOR080W	intact:EBI-412442|uniprotkb:P25589|uniprotkb:P27513|uniprotkb:P87003|uniprotkb:Q07218|uniprotkb:Q8NIN2|uniprotkb:D6VQV6|ensemblfungi:YCL061C	psi-mi:dia2_yeast(display_long)|uniprotkb:Digs into agar protein 2(gene name synonym)|uniprotkb:DIA2(gene name)|psi-mi:DIA2(display_short)|uniprotkb:YOR29-31(orf name)|uniprotkb:YOR080W(locus name)	psi-mi:mrc1_yeast(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:YCL061C(locus name)|uniprotkb:YCL61C/YCL60C(orf name)|uniprotkb:DNA replication checkpoint mediator MRC1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594534|mint:MINT-7542511|imex:IM-13898-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014723.2|sgd:S000005606|dip:DIP-6496N|mint:Q08496|ensemblfungi:YOR080W(gene)|ensemblfungi:YOR080W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043624"|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032675|interpro:IPR036047|mint:MINT-7542519(identity)	refseq:NP_009871.2|sgd:S000000566|ensemblfungi:YCL061C(gene)|ensemblfungi:YCL061C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|interpro:IPR018564|go:"GO:0000723"(telomere maintenance)|mint:P25588|dip:DIP-1017N|mint:MINT-7542517(identity)	-	crc64:98B610994BA2F803	crc64:378345EE503FFA81	figure legend:f2d|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/12/29	2014/10/16	rogid:/hUI8VOftN8vuZMVkGk/6c0Zj2I559292	rogid:Sv9pZwka0vVslquPGLQ2N/R7W/w559292	intact-crc:D8B602FA19DBAFF5|rigid:cepHbOfaV3JWwm4q1Aou1ywu7PE	false	mutation increasing interaction:210-249(MINT-7556245)	binding-associated region:701-800(MINT-7542530)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08496	uniprotkb:Q01454	intact:EBI-31943|uniprotkb:O00034|uniprotkb:Q7LGN4|uniprotkb:D6W2E3|ensemblfungi:YOR080W	intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W	psi-mi:dia2_yeast(display_long)|uniprotkb:Digs into agar protein 2(gene name synonym)|uniprotkb:DIA2(gene name)|psi-mi:DIA2(display_short)|uniprotkb:YOR29-31(orf name)|uniprotkb:YOR080W(locus name)	psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594553|mint:MINT-7556160|imex:IM-13898-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014723.2|sgd:S000005606|dip:DIP-6496N|mint:Q08496|ensemblfungi:YOR080W(gene)|ensemblfungi:YOR080W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043624"|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032675|interpro:IPR036047|mint:MINT-7556168(identity)	refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|mint:MINT-7556162(identity)	-	crc64:98B610994BA2F803	crc64:E2ABBB244B5F8B4D	figure legend:f1a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/12/29	2014/10/16	rogid:/hUI8VOftN8vuZMVkGk/6c0Zj2I559292	rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292	intact-crc:7953FA26532CC81F|rigid:So4QBDmxqe1+l8/HkoKdVkIWX80	false	fusion protein:?-?(MINT-7556197)|mutation increasing interaction:210-249(MINT-7556169)	fusion protein:?-?(MINT-7556200)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P29469	uniprotkb:Q08496	intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7	intact:EBI-31943|uniprotkb:O00034|uniprotkb:Q7LGN4|uniprotkb:D6W2E3|ensemblfungi:YOR080W	psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)	psi-mi:dia2_yeast(display_long)|uniprotkb:Digs into agar protein 2(gene name synonym)|uniprotkb:DIA2(gene name)|psi-mi:DIA2(display_short)|uniprotkb:YOR29-31(orf name)|uniprotkb:YOR080W(locus name)	psi-mi:"MI:0018"(two hybrid)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594511|mint:MINT-7542435|imex:IM-13898-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N|mint:MINT-7542445(identity)	refseq:NP_014723.2|sgd:S000005606|dip:DIP-6496N|mint:Q08496|ensemblfungi:YOR080W(gene)|ensemblfungi:YOR080W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043624"|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032675|interpro:IPR036047|mint:MINT-7542439(identity)	-	crc64:F38FF682581B0EC0	crc64:98B610994BA2F803	figure legend:f2a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/12/29	2014/10/16	rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292	rogid:/hUI8VOftN8vuZMVkGk/6c0Zj2I559292	intact-crc:7E820A1F127B7BF5|rigid:or32IlSVS25EawNzOAJ5cEUOyHE	false	-	binding-associated region:?-?(MINT-7542440)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08496	uniprotkb:P25588	intact:EBI-31943|uniprotkb:O00034|uniprotkb:Q7LGN4|uniprotkb:D6W2E3|ensemblfungi:YOR080W	intact:EBI-412442|uniprotkb:P25589|uniprotkb:P27513|uniprotkb:P87003|uniprotkb:Q07218|uniprotkb:Q8NIN2|uniprotkb:D6VQV6|ensemblfungi:YCL061C	psi-mi:dia2_yeast(display_long)|uniprotkb:Digs into agar protein 2(gene name synonym)|uniprotkb:DIA2(gene name)|psi-mi:DIA2(display_short)|uniprotkb:YOR29-31(orf name)|uniprotkb:YOR080W(locus name)	psi-mi:mrc1_yeast(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:YCL061C(locus name)|uniprotkb:YCL61C/YCL60C(orf name)|uniprotkb:DNA replication checkpoint mediator MRC1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594597|mint:MINT-7556249|imex:IM-13898-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014723.2|sgd:S000005606|dip:DIP-6496N|mint:Q08496|ensemblfungi:YOR080W(gene)|ensemblfungi:YOR080W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043624"|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032675|interpro:IPR036047|mint:MINT-7556251(identity)	refseq:NP_009871.2|sgd:S000000566|ensemblfungi:YCL061C(gene)|ensemblfungi:YCL061C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|interpro:IPR018564|go:"GO:0000723"(telomere maintenance)|mint:P25588|dip:DIP-1017N|mint:MINT-7556255(identity)	-	crc64:98B610994BA2F803	crc64:378345EE503FFA81	figure legend:f2d|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/12/29	2014/10/16	rogid:/hUI8VOftN8vuZMVkGk/6c0Zj2I559292	rogid:Sv9pZwka0vVslquPGLQ2N/R7W/w559292	intact-crc:C58D98D5800DE299|rigid:cepHbOfaV3JWwm4q1Aou1ywu7PE	false	mutation increasing interaction:210-249(MINT-7556252)	binding-associated region:380-557(MINT-7556256)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29469	uniprotkb:Q08496	intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7	intact:EBI-31943|uniprotkb:O00034|uniprotkb:Q7LGN4|uniprotkb:D6W2E3|ensemblfungi:YOR080W	psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)	psi-mi:dia2_yeast(display_long)|uniprotkb:Digs into agar protein 2(gene name synonym)|uniprotkb:DIA2(gene name)|psi-mi:DIA2(display_short)|uniprotkb:YOR29-31(orf name)|uniprotkb:YOR080W(locus name)	psi-mi:"MI:0018"(two hybrid)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594575|mint:MINT-7556173|imex:IM-13898-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N|mint:MINT-7556181(identity)	refseq:NP_014723.2|sgd:S000005606|dip:DIP-6496N|mint:Q08496|ensemblfungi:YOR080W(gene)|ensemblfungi:YOR080W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043624"|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032675|interpro:IPR036047|mint:MINT-7556175(identity)	-	crc64:F38FF682581B0EC0	crc64:98B610994BA2F803	figure legend:f1a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/12/29	2014/10/16	rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292	rogid:/hUI8VOftN8vuZMVkGk/6c0Zj2I559292	intact-crc:AD9E1B895DA31CE8|rigid:or32IlSVS25EawNzOAJ5cEUOyHE	false	fusion protein:?-?(MINT-7556209)	mutation increasing interaction:210-249(MINT-7556176)|fusion protein:?-?(MINT-7556212)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25588	uniprotkb:Q08496	intact:EBI-412442|uniprotkb:P25589|uniprotkb:P27513|uniprotkb:P87003|uniprotkb:Q07218|uniprotkb:Q8NIN2|uniprotkb:D6VQV6|ensemblfungi:YCL061C	intact:EBI-31943|uniprotkb:O00034|uniprotkb:Q7LGN4|uniprotkb:D6W2E3|ensemblfungi:YOR080W	psi-mi:mrc1_yeast(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:YCL061C(locus name)|uniprotkb:YCL61C/YCL60C(orf name)|uniprotkb:DNA replication checkpoint mediator MRC1(gene name synonym)	psi-mi:dia2_yeast(display_long)|uniprotkb:Digs into agar protein 2(gene name synonym)|uniprotkb:DIA2(gene name)|psi-mi:DIA2(display_short)|uniprotkb:YOR29-31(orf name)|uniprotkb:YOR080W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594678|mint:MINT-7542487|imex:IM-13898-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009871.2|sgd:S000000566|ensemblfungi:YCL061C(gene)|ensemblfungi:YCL061C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|interpro:IPR018564|go:"GO:0000723"(telomere maintenance)|mint:P25588|dip:DIP-1017N|mint:MINT-7542489(identity)	refseq:NP_014723.2|sgd:S000005606|dip:DIP-6496N|mint:Q08496|ensemblfungi:YOR080W(gene)|ensemblfungi:YOR080W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043624"|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032675|interpro:IPR036047|mint:MINT-7542490(identity)	-	crc64:378345EE503FFA81	crc64:98B610994BA2F803	figure legend:f2c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2009/12/29	2014/10/16	rogid:Sv9pZwka0vVslquPGLQ2N/R7W/w559292	rogid:/hUI8VOftN8vuZMVkGk/6c0Zj2I559292	intact-crc:E51F5248B7817642|rigid:cepHbOfaV3JWwm4q1Aou1ywu7PE	false	flag tag:?-?(MINT-7542493)	ha tag:?-?(MINT-7542507)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q08496	uniprotkb:P25588	intact:EBI-31943|uniprotkb:O00034|uniprotkb:Q7LGN4|uniprotkb:D6W2E3|ensemblfungi:YOR080W	intact:EBI-412442|uniprotkb:P25589|uniprotkb:P27513|uniprotkb:P87003|uniprotkb:Q07218|uniprotkb:Q8NIN2|uniprotkb:D6VQV6|ensemblfungi:YCL061C	psi-mi:dia2_yeast(display_long)|uniprotkb:Digs into agar protein 2(gene name synonym)|uniprotkb:DIA2(gene name)|psi-mi:DIA2(display_short)|uniprotkb:YOR29-31(orf name)|uniprotkb:YOR080W(locus name)	psi-mi:mrc1_yeast(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:YCL061C(locus name)|uniprotkb:YCL61C/YCL60C(orf name)|uniprotkb:DNA replication checkpoint mediator MRC1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594625|mint:MINT-7501126|imex:IM-13898-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014723.2|sgd:S000005606|dip:DIP-6496N|mint:Q08496|ensemblfungi:YOR080W(gene)|ensemblfungi:YOR080W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043624"|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032675|interpro:IPR036047|mint:MINT-7501128(identity)	refseq:NP_009871.2|sgd:S000000566|ensemblfungi:YCL061C(gene)|ensemblfungi:YCL061C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|interpro:IPR018564|go:"GO:0000723"(telomere maintenance)|mint:P25588|dip:DIP-1017N|mint:MINT-7501129(identity)	-	crc64:98B610994BA2F803	crc64:378345EE503FFA81	figure legend:f1c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2009/12/29	2014/10/16	rogid:/hUI8VOftN8vuZMVkGk/6c0Zj2I559292	rogid:Sv9pZwka0vVslquPGLQ2N/R7W/w559292	intact-crc:5AD7F2CADF2497C8|rigid:cepHbOfaV3JWwm4q1Aou1ywu7PE	false	ha tag:?-?(MINT-7542364)	flag tag:?-?(MINT-7542367)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P25588	uniprotkb:Q08496	intact:EBI-412442|uniprotkb:P25589|uniprotkb:P27513|uniprotkb:P87003|uniprotkb:Q07218|uniprotkb:Q8NIN2|uniprotkb:D6VQV6|ensemblfungi:YCL061C	intact:EBI-31943|uniprotkb:O00034|uniprotkb:Q7LGN4|uniprotkb:D6W2E3|ensemblfungi:YOR080W	psi-mi:mrc1_yeast(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:YCL061C(locus name)|uniprotkb:YCL61C/YCL60C(orf name)|uniprotkb:DNA replication checkpoint mediator MRC1(gene name synonym)	psi-mi:dia2_yeast(display_long)|uniprotkb:Digs into agar protein 2(gene name synonym)|uniprotkb:DIA2(gene name)|psi-mi:DIA2(display_short)|uniprotkb:YOR29-31(orf name)|uniprotkb:YOR080W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594660|mint:MINT-7501935|imex:IM-13898-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009871.2|sgd:S000000566|ensemblfungi:YCL061C(gene)|ensemblfungi:YCL061C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|interpro:IPR018564|go:"GO:0000723"(telomere maintenance)|mint:P25588|dip:DIP-1017N|mint:MINT-7501937(identity)	refseq:NP_014723.2|sgd:S000005606|dip:DIP-6496N|mint:Q08496|ensemblfungi:YOR080W(gene)|ensemblfungi:YOR080W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043624"|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032675|interpro:IPR036047|mint:MINT-7501939(identity)	-	crc64:378345EE503FFA81	crc64:98B610994BA2F803	figure legend:f1c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_21)|taxid:7108(Spodoptera frugiperda insect cells)	-	2009/12/29	2014/10/16	rogid:Sv9pZwka0vVslquPGLQ2N/R7W/w559292	rogid:/hUI8VOftN8vuZMVkGk/6c0Zj2I559292	intact-crc:EAEBE198303D09F2|rigid:cepHbOfaV3JWwm4q1Aou1ywu7PE	false	flag tag:?-?(MINT-7542361)	ha tag:?-?(MINT-7542358)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q08496	uniprotkb:P25588	intact:EBI-31943|uniprotkb:O00034|uniprotkb:Q7LGN4|uniprotkb:D6W2E3|ensemblfungi:YOR080W	intact:EBI-412442|uniprotkb:P25589|uniprotkb:P27513|uniprotkb:P87003|uniprotkb:Q07218|uniprotkb:Q8NIN2|uniprotkb:D6VQV6|ensemblfungi:YCL061C	psi-mi:dia2_yeast(display_long)|uniprotkb:Digs into agar protein 2(gene name synonym)|uniprotkb:DIA2(gene name)|psi-mi:DIA2(display_short)|uniprotkb:YOR29-31(orf name)|uniprotkb:YOR080W(locus name)	psi-mi:mrc1_yeast(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:YCL061C(locus name)|uniprotkb:YCL61C/YCL60C(orf name)|uniprotkb:DNA replication checkpoint mediator MRC1(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594704|mint:MINT-7514674|imex:IM-13898-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014723.2|sgd:S000005606|dip:DIP-6496N|mint:Q08496|ensemblfungi:YOR080W(gene)|ensemblfungi:YOR080W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043624"|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032675|interpro:IPR036047|mint:MINT-7514677(identity)	refseq:NP_009871.2|sgd:S000000566|ensemblfungi:YCL061C(gene)|ensemblfungi:YCL061C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|interpro:IPR018564|go:"GO:0000723"(telomere maintenance)|mint:P25588|dip:DIP-1017N|mint:MINT-7514676(identity)	-	crc64:98B610994BA2F803	crc64:378345EE503FFA81	figure legend:f1d|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/12/29	2014/10/16	rogid:/hUI8VOftN8vuZMVkGk/6c0Zj2I559292	rogid:Sv9pZwka0vVslquPGLQ2N/R7W/w559292	intact-crc:AFB2E0A9C20D82AF|rigid:cepHbOfaV3JWwm4q1Aou1ywu7PE	false	flag tag:?-?(MINT-7542370)	myc tag:?-?(MINT-7542374)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q08496	uniprotkb:P29469	intact:EBI-31943|uniprotkb:O00034|uniprotkb:Q7LGN4|uniprotkb:D6W2E3|ensemblfungi:YOR080W	intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7	psi-mi:dia2_yeast(display_long)|uniprotkb:Digs into agar protein 2(gene name synonym)|uniprotkb:DIA2(gene name)|psi-mi:DIA2(display_short)|uniprotkb:YOR29-31(orf name)|uniprotkb:YOR080W(locus name)	psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594792|mint:MINT-7542452|imex:IM-13898-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014723.2|sgd:S000005606|dip:DIP-6496N|mint:Q08496|ensemblfungi:YOR080W(gene)|ensemblfungi:YOR080W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043624"|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032675|interpro:IPR036047|mint:MINT-7542454(identity)	refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N|mint:MINT-7542455(identity)	-	crc64:98B610994BA2F803	crc64:F38FF682581B0EC0	figure legend:f2b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/12/29	2014/10/16	rogid:/hUI8VOftN8vuZMVkGk/6c0Zj2I559292	rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292	intact-crc:63C518D94E4E02CA|rigid:W/vsCHGY1sN4c2OBDMC5xK/q418	false	ha tag:?-?(MINT-7542458)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q08496	uniprotkb:P25588	intact:EBI-31943|uniprotkb:O00034|uniprotkb:Q7LGN4|uniprotkb:D6W2E3|ensemblfungi:YOR080W	intact:EBI-412442|uniprotkb:P25589|uniprotkb:P27513|uniprotkb:P87003|uniprotkb:Q07218|uniprotkb:Q8NIN2|uniprotkb:D6VQV6|ensemblfungi:YCL061C	psi-mi:dia2_yeast(display_long)|uniprotkb:Digs into agar protein 2(gene name synonym)|uniprotkb:DIA2(gene name)|psi-mi:DIA2(display_short)|uniprotkb:YOR29-31(orf name)|uniprotkb:YOR080W(locus name)	psi-mi:mrc1_yeast(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:YCL061C(locus name)|uniprotkb:YCL61C/YCL60C(orf name)|uniprotkb:DNA replication checkpoint mediator MRC1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594792|mint:MINT-7542452|imex:IM-13898-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014723.2|sgd:S000005606|dip:DIP-6496N|mint:Q08496|ensemblfungi:YOR080W(gene)|ensemblfungi:YOR080W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043624"|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032675|interpro:IPR036047|mint:MINT-7542454(identity)	refseq:NP_009871.2|sgd:S000000566|ensemblfungi:YCL061C(gene)|ensemblfungi:YCL061C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|interpro:IPR018564|go:"GO:0000723"(telomere maintenance)|mint:P25588|dip:DIP-1017N|mint:MINT-7542456(identity)	-	crc64:98B610994BA2F803	crc64:378345EE503FFA81	figure legend:f2b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/12/29	2014/10/16	rogid:/hUI8VOftN8vuZMVkGk/6c0Zj2I559292	rogid:Sv9pZwka0vVslquPGLQ2N/R7W/w559292	intact-crc:63C518D94E4E02CA|rigid:W/vsCHGY1sN4c2OBDMC5xK/q418	false	ha tag:?-?(MINT-7542458)	myc tag:?-?(MINT-7542464)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q01454	uniprotkb:Q08496	intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W	intact:EBI-31943|uniprotkb:O00034|uniprotkb:Q7LGN4|uniprotkb:D6W2E3|ensemblfungi:YOR080W	psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym)	psi-mi:dia2_yeast(display_long)|uniprotkb:Digs into agar protein 2(gene name synonym)|uniprotkb:DIA2(gene name)|psi-mi:DIA2(display_short)|uniprotkb:YOR29-31(orf name)|uniprotkb:YOR080W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594771|mint:MINT-7542394|imex:IM-13898-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|mint:MINT-7542397(identity)	refseq:NP_014723.2|sgd:S000005606|dip:DIP-6496N|mint:Q08496|ensemblfungi:YOR080W(gene)|ensemblfungi:YOR080W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043624"|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032675|interpro:IPR036047|mint:MINT-7542396(identity)	-	crc64:E2ABBB244B5F8B4D	crc64:98B610994BA2F803	figure legend:f1e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/12/29	2014/10/16	rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292	rogid:/hUI8VOftN8vuZMVkGk/6c0Zj2I559292	intact-crc:77FF858BE74A3123|rigid:So4QBDmxqe1+l8/HkoKdVkIWX80	false	ha tag:?-?(MINT-7542399)	flag tag:?-?(MINT-7542403)|mutation increasing interaction:210-249(MINT-7556234)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q08496	uniprotkb:P25588	intact:EBI-31943|uniprotkb:O00034|uniprotkb:Q7LGN4|uniprotkb:D6W2E3|ensemblfungi:YOR080W	intact:EBI-412442|uniprotkb:P25589|uniprotkb:P27513|uniprotkb:P87003|uniprotkb:Q07218|uniprotkb:Q8NIN2|uniprotkb:D6VQV6|ensemblfungi:YCL061C	psi-mi:dia2_yeast(display_long)|uniprotkb:Digs into agar protein 2(gene name synonym)|uniprotkb:DIA2(gene name)|psi-mi:DIA2(display_short)|uniprotkb:YOR29-31(orf name)|uniprotkb:YOR080W(locus name)	psi-mi:mrc1_yeast(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:YCL061C(locus name)|uniprotkb:YCL61C/YCL60C(orf name)|uniprotkb:DNA replication checkpoint mediator MRC1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594730|mint:MINT-7542381|imex:IM-13898-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014723.2|sgd:S000005606|dip:DIP-6496N|mint:Q08496|ensemblfungi:YOR080W(gene)|ensemblfungi:YOR080W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006348"|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043624"|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032675|interpro:IPR036047|mint:MINT-7542383(identity)	refseq:NP_009871.2|sgd:S000000566|ensemblfungi:YCL061C(gene)|ensemblfungi:YCL061C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|interpro:IPR018564|go:"GO:0000723"(telomere maintenance)|mint:P25588|dip:DIP-1017N|mint:MINT-7542384(identity)	-	crc64:98B610994BA2F803	crc64:378345EE503FFA81	figure legend:f1e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/12/29	2014/10/16	rogid:/hUI8VOftN8vuZMVkGk/6c0Zj2I559292	rogid:Sv9pZwka0vVslquPGLQ2N/R7W/w559292	intact-crc:4D3DF688B1A04342|rigid:cepHbOfaV3JWwm4q1Aou1ywu7PE	false	flag tag:?-?(MINT-7542390)|mutation increasing interaction:210-249(MINT-7556239)	myc tag:?-?(MINT-7542386)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P30665	uniprotkb:P25588	intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W	intact:EBI-412442|uniprotkb:P25589|uniprotkb:P27513|uniprotkb:P87003|uniprotkb:Q07218|uniprotkb:Q8NIN2|uniprotkb:D6VQV6|ensemblfungi:YCL061C	psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym)	psi-mi:mrc1_yeast(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:YCL061C(locus name)|uniprotkb:YCL61C/YCL60C(orf name)|uniprotkb:DNA replication checkpoint mediator MRC1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594812|mint:MINT-7542572|imex:IM-13898-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|mint:MINT-7542576(identity)	refseq:NP_009871.2|sgd:S000000566|ensemblfungi:YCL061C(gene)|ensemblfungi:YCL061C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|interpro:IPR018564|go:"GO:0000723"(telomere maintenance)|mint:P25588|dip:DIP-1017N|mint:MINT-7542575(identity)	-	crc64:382D542AE38975E3	crc64:378345EE503FFA81	figure legend:f4d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/12/29	2014/10/16	rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292	rogid:Sv9pZwka0vVslquPGLQ2N/R7W/w559292	intact-crc:2A953899C8A749F9|rigid:NPCFH34/hqc0TzlBW14J+r6wSto	false	flag tag:?-?(MINT-7542577)	myc tag:?-?(MINT-7542581)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P30665	uniprotkb:P29469	intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W	intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7	psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym)	psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594812|mint:MINT-7542572|imex:IM-13898-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|mint:MINT-7542576(identity)	refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N|mint:MINT-7542574(identity)	-	crc64:382D542AE38975E3	crc64:F38FF682581B0EC0	figure legend:f4d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/12/29	2014/10/16	rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292	rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292	intact-crc:2A953899C8A749F9|rigid:NPCFH34/hqc0TzlBW14J+r6wSto	false	flag tag:?-?(MINT-7542577)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P30665	uniprotkb:Q01454	intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W	intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W	psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym)	psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594852|mint:MINT-7542590|imex:IM-13898-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|mint:MINT-7542592(identity)	refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|mint:MINT-7542603(identity)	-	crc64:382D542AE38975E3	crc64:E2ABBB244B5F8B4D	figure legend:f4g|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/12/29	2014/10/16	rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292	rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292	intact-crc:A9F015516DE13FA4|rigid:/6NZv++9951H/Q1T/jiShmpI4u0	false	flag tag:?-?(MINT-7542593)	ha tag:?-?(MINT-7542604)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P30665	uniprotkb:P29469	intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W	intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7	psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym)	psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mimura et al. (2009)	pubmed:19910927|imex:IM-13898|mint:MINT-7433832|doi:10.1038/emboj.2009.320	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594852|mint:MINT-7542590|imex:IM-13898-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|mint:MINT-7542592(identity)	refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N|mint:MINT-7542600(identity)	-	crc64:382D542AE38975E3	crc64:F38FF682581B0EC0	figure legend:f4g|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/12/29	2014/10/16	rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292	rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292	intact-crc:A9F015516DE13FA4|rigid:/6NZv++9951H/Q1T/jiShmpI4u0	false	flag tag:?-?(MINT-7542593)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)