#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0A825 uniprotkb:P0A825 intact:EBI-909080|uniprotkb:P00477|ensemblbacteria:AAC75604|ensemblbacteria:BAA16459 intact:EBI-909080|uniprotkb:P00477|ensemblbacteria:AAC75604|ensemblbacteria:BAA16459 psi-mi:glya_ecoli(display_long)|uniprotkb:glyA(gene name)|psi-mi:glyA(display_short)|uniprotkb:b2551(locus name)|uniprotkb:JW2535(locus name) psi-mi:glya_ecoli(display_long)|uniprotkb:glyA(gene name)|psi-mi:glyA(display_short)|uniprotkb:b2551(locus name)|uniprotkb:JW2535(locus name) psi-mi:"MI:0028"(cosedimentation in solution) Florio et al. (2009) pubmed:19909338|imex:IM-15545|mint:MINT-7293368|doi:10.1111/j.1742-4658.2009.07442 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7589064|mint:MINT-7293394|imex:IM-15545-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417046.1|refseq:WP_000919159.1|mint:P0A825|dip:DIP-36205N|ensemblbacteria:AAC75604(transcript)|ensemblbacteria:b2551(gene)|ensemblbacteria:BAA16459(gene)|ensemblbacteria:BAA16459(transcript)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006546"(glycine catabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042802"(identical protein binding)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0070905"(serine binding)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|rcsb pdb:1DFO|rcsb pdb:1EQB|rcsb pdb:3G8M|mint:MINT-7293396(identity) refseq:NP_417046.1|refseq:WP_000919159.1|mint:P0A825|dip:DIP-36205N|ensemblbacteria:AAC75604(transcript)|ensemblbacteria:b2551(gene)|ensemblbacteria:BAA16459(gene)|ensemblbacteria:BAA16459(transcript)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006546"(glycine catabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042802"(identical protein binding)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0070905"(serine binding)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|rcsb pdb:1DFO|rcsb pdb:1EQB|rcsb pdb:3G8M|mint:MINT-7293396(identity) - comment:"Stoichiometry: 2.0" comment:"Stoichiometry: 2.0" figure legend:F4 T2|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/16 2014/10/16 rogid:RihO+Pg6sLFNN8t9TWf9l69O9x083333 rogid:RihO+Pg6sLFNN8t9TWf9l69O9x083333 intact-crc:CDA61F0EA4695735|rigid:/tKvxwqDzkc76A8Ojb78OFNp4Y4 false mutation decreasing interaction:85-85(MINT-7293399) mutation decreasing interaction:85-85(MINT-7293399) 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0A825 uniprotkb:P0A825 intact:EBI-909080|uniprotkb:P00477|ensemblbacteria:AAC75604|ensemblbacteria:BAA16459 intact:EBI-909080|uniprotkb:P00477|ensemblbacteria:AAC75604|ensemblbacteria:BAA16459 psi-mi:glya_ecoli(display_long)|uniprotkb:glyA(gene name)|psi-mi:glyA(display_short)|uniprotkb:b2551(locus name)|uniprotkb:JW2535(locus name) psi-mi:glya_ecoli(display_long)|uniprotkb:glyA(gene name)|psi-mi:glyA(display_short)|uniprotkb:b2551(locus name)|uniprotkb:JW2535(locus name) psi-mi:"MI:0028"(cosedimentation in solution) Florio et al. (2009) pubmed:19909338|imex:IM-15545|mint:MINT-7293368|doi:10.1111/j.1742-4658.2009.07442 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7589113|mint:MINT-7293418|imex:IM-15545-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417046.1|refseq:WP_000919159.1|mint:P0A825|dip:DIP-36205N|ensemblbacteria:AAC75604(transcript)|ensemblbacteria:b2551(gene)|ensemblbacteria:BAA16459(gene)|ensemblbacteria:BAA16459(transcript)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006546"(glycine catabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042802"(identical protein binding)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0070905"(serine binding)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|rcsb pdb:1DFO|rcsb pdb:1EQB|rcsb pdb:3G8M|mint:MINT-7293420(identity) refseq:NP_417046.1|refseq:WP_000919159.1|mint:P0A825|dip:DIP-36205N|ensemblbacteria:AAC75604(transcript)|ensemblbacteria:b2551(gene)|ensemblbacteria:BAA16459(gene)|ensemblbacteria:BAA16459(transcript)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006546"(glycine catabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042802"(identical protein binding)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0070905"(serine binding)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|rcsb pdb:1DFO|rcsb pdb:1EQB|rcsb pdb:3G8M|mint:MINT-7293420(identity) - comment:"Stoichiometry: 2.0" comment:"Stoichiometry: 2.0" figure legend:F4 T2|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/16 2014/10/16 rogid:RihO+Pg6sLFNN8t9TWf9l69O9x083333 rogid:RihO+Pg6sLFNN8t9TWf9l69O9x083333 intact-crc:0D6494C0AC320687|rigid:/tKvxwqDzkc76A8Ojb78OFNp4Y4 false mutation disrupting interaction:276-276(MINT-7293421) mutation disrupting interaction:276-276(MINT-7293421) 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0A825 uniprotkb:P0A825 intact:EBI-909080|uniprotkb:P00477|ensemblbacteria:AAC75604|ensemblbacteria:BAA16459 intact:EBI-909080|uniprotkb:P00477|ensemblbacteria:AAC75604|ensemblbacteria:BAA16459 psi-mi:glya_ecoli(display_long)|uniprotkb:glyA(gene name)|psi-mi:glyA(display_short)|uniprotkb:b2551(locus name)|uniprotkb:JW2535(locus name) psi-mi:glya_ecoli(display_long)|uniprotkb:glyA(gene name)|psi-mi:glyA(display_short)|uniprotkb:b2551(locus name)|uniprotkb:JW2535(locus name) psi-mi:"MI:0028"(cosedimentation in solution) Florio et al. (2009) pubmed:19909338|imex:IM-15545|mint:MINT-7293368|doi:10.1111/j.1742-4658.2009.07442 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7589095|mint:MINT-7293405|imex:IM-15545-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417046.1|refseq:WP_000919159.1|mint:P0A825|dip:DIP-36205N|ensemblbacteria:AAC75604(transcript)|ensemblbacteria:b2551(gene)|ensemblbacteria:BAA16459(gene)|ensemblbacteria:BAA16459(transcript)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006546"(glycine catabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042802"(identical protein binding)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0070905"(serine binding)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|rcsb pdb:1DFO|rcsb pdb:1EQB|rcsb pdb:3G8M|mint:MINT-7293407(identity) refseq:NP_417046.1|refseq:WP_000919159.1|mint:P0A825|dip:DIP-36205N|ensemblbacteria:AAC75604(transcript)|ensemblbacteria:b2551(gene)|ensemblbacteria:BAA16459(gene)|ensemblbacteria:BAA16459(transcript)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006546"(glycine catabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042802"(identical protein binding)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0070905"(serine binding)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|rcsb pdb:1DFO|rcsb pdb:1EQB|rcsb pdb:3G8M|mint:MINT-7293407(identity) - comment:"Stoichiometry: 2.0" comment:"Stoichiometry: 2.0" figure legend:F4 T2|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/16 2014/10/16 rogid:RihO+Pg6sLFNN8t9TWf9l69O9x083333 rogid:RihO+Pg6sLFNN8t9TWf9l69O9x083333 intact-crc:C64895492A7D8D9E|rigid:/tKvxwqDzkc76A8Ojb78OFNp4Y4 false mutation disrupting interaction:85-85(MINT-7293408)|mutation disrupting interaction:276-276(MINT-7293412) mutation disrupting interaction:85-85(MINT-7293408)|mutation disrupting interaction:276-276(MINT-7293412) 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)