#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P30665 uniprotkb:P24279 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-10541|ensemblfungi:YEL032W|uniprotkb:D3DLL7 psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:mcm3_yeast(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:YEL032W(locus name)|uniprotkb:SYGP-ORF23(orf name)|uniprotkb:Minichromosome maintenance protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Remus et al. (2009) imex:IM-12106|pubmed:19896182 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479154|imex:IM-12106-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 refseq:NP_010882.1|sgd:S000000758|go:"GO:0005524"(ATP binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1904931"(MCM complex binding)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGC|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:5XF8|ensemblfungi:YEL032W(gene)|ensemblfungi:YEL032W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|mint:P24279|dip:DIP-2407N psi-mi:"MI:0469"(intact) crc64:382D542AE38975E3 crc64:43DD4DACAF4456DC figure legend:Fig. 4|complex-properties:"The loaded complex appears to be a double hexamer of Mcm2-7 (150 A x 230 A)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/16 2014/10/16 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:OsFbdaTeE1vPQObriGt5M6mTPzk559292 intact-crc:FF8BA89C04A228CD|rigid:/LrzbqN/GFaIBfixW0XN+yqWr78 false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30665 uniprotkb:P53091 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-10556|uniprotkb:Q870M9|ensemblfungi:YGL201C|uniprotkb:D6VTV3 psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:mcm6_yeast(display_long)|uniprotkb:YGL201C(locus name)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:Minichromosome maintenance protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Remus et al. (2009) imex:IM-12106|pubmed:19896182 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479154|imex:IM-12106-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 ensemblfungi:YGL201C(gene)|refseq:NP_011314.2|sgd:S000003169|ensemblfungi:YGL201C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:5V8F|mint:P53091|dip:DIP-1294N psi-mi:"MI:0469"(intact) crc64:382D542AE38975E3 crc64:03AB793134E64A50 figure legend:Fig. 4|complex-properties:"The loaded complex appears to be a double hexamer of Mcm2-7 (150 A x 230 A)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/16 2014/10/16 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:b2Pak0d6eENHIzSFaBge/kPQceU559292 intact-crc:FF8BA89C04A228CD|rigid:/LrzbqN/GFaIBfixW0XN+yqWr78 false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30665 uniprotkb:P29469 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Remus et al. (2009) imex:IM-12106|pubmed:19896182 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479154|imex:IM-12106-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N psi-mi:"MI:0469"(intact) crc64:382D542AE38975E3 crc64:F38FF682581B0EC0 figure legend:Fig. 4|complex-properties:"The loaded complex appears to be a double hexamer of Mcm2-7 (150 A x 230 A)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/16 2014/10/16 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 intact-crc:FF8BA89C04A228CD|rigid:/LrzbqN/GFaIBfixW0XN+yqWr78 false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30665 uniprotkb:P38132 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-4300|uniprotkb:D6VQK0|ensemblfungi:YBR202W psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:mcm7_yeast(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:YBR202W(locus name)|uniprotkb:YBR1441(orf name)|uniprotkb:CDC47(gene name synonym)|uniprotkb:Cell division control protein 47(gene name synonym)|uniprotkb:Minichromosome maintenance protein 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Remus et al. (2009) imex:IM-12106|pubmed:19896182 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479154|imex:IM-12106-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 dip:DIP-2408N|sgd:S000000406|refseq:NP_009761.4|mint:P38132|ensemblfungi:YBR202W(gene)|ensemblfungi:YBR202W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904931"(MCM complex binding)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGC|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 psi-mi:"MI:0469"(intact) crc64:382D542AE38975E3 crc64:ADA66C719D96DB4A figure legend:Fig. 4|complex-properties:"The loaded complex appears to be a double hexamer of Mcm2-7 (150 A x 230 A)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/16 2014/10/16 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:OJMt3vgMFg5we7rPkQSmkxbL1dA559292 intact-crc:FF8BA89C04A228CD|rigid:/LrzbqN/GFaIBfixW0XN+yqWr78 false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30665 uniprotkb:P29496 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-10549|ensemblfungi:YLR274W|uniprotkb:D6VYS1 psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:mcm5_yeast(display_long)|uniprotkb:MCM5(gene name)|psi-mi:MCM5(display_short)|uniprotkb:CDC46(gene name synonym)|uniprotkb:YLR274W(locus name)|uniprotkb:L9328.1(orf name)|uniprotkb:Cell division control protein 46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Remus et al. (2009) imex:IM-12106|pubmed:19896182 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479154|imex:IM-12106-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 refseq:NP_013376.1|sgd:S000004264|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:3JC5|rcsb pdb:6WGG|rcsb pdb:6WGI|ensemblfungi:YLR274W(gene)|ensemblfungi:YLR274W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|reactome:R-SCE-68949|reactome:R-SCE-69052|reactome:R-SCE-68962|dip:DIP-2406N psi-mi:"MI:0469"(intact) crc64:382D542AE38975E3 crc64:01D9DE208A091CF2 figure legend:Fig. 4|complex-properties:"The loaded complex appears to be a double hexamer of Mcm2-7 (150 A x 230 A)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/16 2014/10/16 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:a8UgYOklJ5vWqhA0hbQTCWNQg0Y559292 intact-crc:FF8BA89C04A228CD|rigid:/LrzbqN/GFaIBfixW0XN+yqWr78 false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P47112 uniprotkb:P29469 intact:EBI-25503|uniprotkb:D6VWL7|ensemblfungi:YJR046W intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 psi-mi:cdt1_yeast(display_long)|uniprotkb:YJR046W(locus name)|uniprotkb:J1641(orf name)|uniprotkb:TAH11(gene name)|psi-mi:TAH11(display_short)|uniprotkb:CDT1(gene name synonym)|uniprotkb:SID2(gene name synonym)|uniprotkb:SIC1 indispensable protein 2(gene name synonym)|uniprotkb:Topoisomerase-A hypersensitive protein 11(gene name synonym) psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Remus et al. (2009) imex:IM-12106|pubmed:19896182 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479172|imex:IM-12106-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003807|refseq:NP_012580.1|dip:DIP-7948N|ensemblfungi:YJR046W(gene)|ensemblfungi:YJR046W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0051301"(cell division)|interpro:IPR032054|interpro:IPR038090|rcsb pdb:5ME9|rcsb pdb:5MEA|rcsb pdb:5MEB|rcsb pdb:5MEC|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6WGG|rcsb pdb:6WGI refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N psi-mi:"MI:0469"(intact) crc64:099992C0E3CCA726 crc64:F38FF682581B0EC0 figure legend:Fig. 1F|complex-properties:Forms globular particles, approximately 15 nm in diameter|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/16 2014/10/16 rogid:bhL1vrVCG3mbWsF2S5nRT+i5fqw559292 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 intact-crc:E2AADFAAB554DCAD|rigid:oQX6ZELpFoTC2wCKzi+QS731NLk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47112 uniprotkb:P24279 intact:EBI-25503|uniprotkb:D6VWL7|ensemblfungi:YJR046W intact:EBI-10541|ensemblfungi:YEL032W|uniprotkb:D3DLL7 psi-mi:cdt1_yeast(display_long)|uniprotkb:YJR046W(locus name)|uniprotkb:J1641(orf name)|uniprotkb:TAH11(gene name)|psi-mi:TAH11(display_short)|uniprotkb:CDT1(gene name synonym)|uniprotkb:SID2(gene name synonym)|uniprotkb:SIC1 indispensable protein 2(gene name synonym)|uniprotkb:Topoisomerase-A hypersensitive protein 11(gene name synonym) psi-mi:mcm3_yeast(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:YEL032W(locus name)|uniprotkb:SYGP-ORF23(orf name)|uniprotkb:Minichromosome maintenance protein 3(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Remus et al. (2009) imex:IM-12106|pubmed:19896182 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479172|imex:IM-12106-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003807|refseq:NP_012580.1|dip:DIP-7948N|ensemblfungi:YJR046W(gene)|ensemblfungi:YJR046W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0051301"(cell division)|interpro:IPR032054|interpro:IPR038090|rcsb pdb:5ME9|rcsb pdb:5MEA|rcsb pdb:5MEB|rcsb pdb:5MEC|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6WGG|rcsb pdb:6WGI refseq:NP_010882.1|sgd:S000000758|go:"GO:0005524"(ATP binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1904931"(MCM complex binding)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGC|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:5XF8|ensemblfungi:YEL032W(gene)|ensemblfungi:YEL032W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|mint:P24279|dip:DIP-2407N psi-mi:"MI:0469"(intact) crc64:099992C0E3CCA726 crc64:43DD4DACAF4456DC figure legend:Fig. 1F|complex-properties:Forms globular particles, approximately 15 nm in diameter|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/16 2014/10/16 rogid:bhL1vrVCG3mbWsF2S5nRT+i5fqw559292 rogid:OsFbdaTeE1vPQObriGt5M6mTPzk559292 intact-crc:E2AADFAAB554DCAD|rigid:oQX6ZELpFoTC2wCKzi+QS731NLk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47112 uniprotkb:P30665 intact:EBI-25503|uniprotkb:D6VWL7|ensemblfungi:YJR046W intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W psi-mi:cdt1_yeast(display_long)|uniprotkb:YJR046W(locus name)|uniprotkb:J1641(orf name)|uniprotkb:TAH11(gene name)|psi-mi:TAH11(display_short)|uniprotkb:CDT1(gene name synonym)|uniprotkb:SID2(gene name synonym)|uniprotkb:SIC1 indispensable protein 2(gene name synonym)|uniprotkb:Topoisomerase-A hypersensitive protein 11(gene name synonym) psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Remus et al. (2009) imex:IM-12106|pubmed:19896182 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479172|imex:IM-12106-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003807|refseq:NP_012580.1|dip:DIP-7948N|ensemblfungi:YJR046W(gene)|ensemblfungi:YJR046W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0051301"(cell division)|interpro:IPR032054|interpro:IPR038090|rcsb pdb:5ME9|rcsb pdb:5MEA|rcsb pdb:5MEB|rcsb pdb:5MEC|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6WGG|rcsb pdb:6WGI dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 psi-mi:"MI:0469"(intact) crc64:099992C0E3CCA726 crc64:382D542AE38975E3 figure legend:Fig. 1F|complex-properties:Forms globular particles, approximately 15 nm in diameter|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/16 2014/10/16 rogid:bhL1vrVCG3mbWsF2S5nRT+i5fqw559292 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 intact-crc:E2AADFAAB554DCAD|rigid:oQX6ZELpFoTC2wCKzi+QS731NLk false - flag tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47112 uniprotkb:P29496 intact:EBI-25503|uniprotkb:D6VWL7|ensemblfungi:YJR046W intact:EBI-10549|ensemblfungi:YLR274W|uniprotkb:D6VYS1 psi-mi:cdt1_yeast(display_long)|uniprotkb:YJR046W(locus name)|uniprotkb:J1641(orf name)|uniprotkb:TAH11(gene name)|psi-mi:TAH11(display_short)|uniprotkb:CDT1(gene name synonym)|uniprotkb:SID2(gene name synonym)|uniprotkb:SIC1 indispensable protein 2(gene name synonym)|uniprotkb:Topoisomerase-A hypersensitive protein 11(gene name synonym) psi-mi:mcm5_yeast(display_long)|uniprotkb:MCM5(gene name)|psi-mi:MCM5(display_short)|uniprotkb:CDC46(gene name synonym)|uniprotkb:YLR274W(locus name)|uniprotkb:L9328.1(orf name)|uniprotkb:Cell division control protein 46(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Remus et al. (2009) imex:IM-12106|pubmed:19896182 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479172|imex:IM-12106-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003807|refseq:NP_012580.1|dip:DIP-7948N|ensemblfungi:YJR046W(gene)|ensemblfungi:YJR046W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0051301"(cell division)|interpro:IPR032054|interpro:IPR038090|rcsb pdb:5ME9|rcsb pdb:5MEA|rcsb pdb:5MEB|rcsb pdb:5MEC|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6WGG|rcsb pdb:6WGI refseq:NP_013376.1|sgd:S000004264|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:3JC5|rcsb pdb:6WGG|rcsb pdb:6WGI|ensemblfungi:YLR274W(gene)|ensemblfungi:YLR274W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|reactome:R-SCE-68949|reactome:R-SCE-69052|reactome:R-SCE-68962|dip:DIP-2406N psi-mi:"MI:0469"(intact) crc64:099992C0E3CCA726 crc64:01D9DE208A091CF2 figure legend:Fig. 1F|complex-properties:Forms globular particles, approximately 15 nm in diameter|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/16 2014/10/16 rogid:bhL1vrVCG3mbWsF2S5nRT+i5fqw559292 rogid:a8UgYOklJ5vWqhA0hbQTCWNQg0Y559292 intact-crc:E2AADFAAB554DCAD|rigid:oQX6ZELpFoTC2wCKzi+QS731NLk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47112 uniprotkb:P53091 intact:EBI-25503|uniprotkb:D6VWL7|ensemblfungi:YJR046W intact:EBI-10556|uniprotkb:Q870M9|ensemblfungi:YGL201C|uniprotkb:D6VTV3 psi-mi:cdt1_yeast(display_long)|uniprotkb:YJR046W(locus name)|uniprotkb:J1641(orf name)|uniprotkb:TAH11(gene name)|psi-mi:TAH11(display_short)|uniprotkb:CDT1(gene name synonym)|uniprotkb:SID2(gene name synonym)|uniprotkb:SIC1 indispensable protein 2(gene name synonym)|uniprotkb:Topoisomerase-A hypersensitive protein 11(gene name synonym) psi-mi:mcm6_yeast(display_long)|uniprotkb:YGL201C(locus name)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:Minichromosome maintenance protein 6(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Remus et al. (2009) imex:IM-12106|pubmed:19896182 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479172|imex:IM-12106-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003807|refseq:NP_012580.1|dip:DIP-7948N|ensemblfungi:YJR046W(gene)|ensemblfungi:YJR046W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0051301"(cell division)|interpro:IPR032054|interpro:IPR038090|rcsb pdb:5ME9|rcsb pdb:5MEA|rcsb pdb:5MEB|rcsb pdb:5MEC|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6WGG|rcsb pdb:6WGI ensemblfungi:YGL201C(gene)|refseq:NP_011314.2|sgd:S000003169|ensemblfungi:YGL201C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:5V8F|mint:P53091|dip:DIP-1294N psi-mi:"MI:0469"(intact) crc64:099992C0E3CCA726 crc64:03AB793134E64A50 figure legend:Fig. 1F|complex-properties:Forms globular particles, approximately 15 nm in diameter|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/16 2014/10/16 rogid:bhL1vrVCG3mbWsF2S5nRT+i5fqw559292 rogid:b2Pak0d6eENHIzSFaBge/kPQceU559292 intact-crc:E2AADFAAB554DCAD|rigid:oQX6ZELpFoTC2wCKzi+QS731NLk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47112 uniprotkb:P38132 intact:EBI-25503|uniprotkb:D6VWL7|ensemblfungi:YJR046W intact:EBI-4300|uniprotkb:D6VQK0|ensemblfungi:YBR202W psi-mi:cdt1_yeast(display_long)|uniprotkb:YJR046W(locus name)|uniprotkb:J1641(orf name)|uniprotkb:TAH11(gene name)|psi-mi:TAH11(display_short)|uniprotkb:CDT1(gene name synonym)|uniprotkb:SID2(gene name synonym)|uniprotkb:SIC1 indispensable protein 2(gene name synonym)|uniprotkb:Topoisomerase-A hypersensitive protein 11(gene name synonym) psi-mi:mcm7_yeast(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:YBR202W(locus name)|uniprotkb:YBR1441(orf name)|uniprotkb:CDC47(gene name synonym)|uniprotkb:Cell division control protein 47(gene name synonym)|uniprotkb:Minichromosome maintenance protein 7(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Remus et al. (2009) imex:IM-12106|pubmed:19896182 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479172|imex:IM-12106-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003807|refseq:NP_012580.1|dip:DIP-7948N|ensemblfungi:YJR046W(gene)|ensemblfungi:YJR046W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0051301"(cell division)|interpro:IPR032054|interpro:IPR038090|rcsb pdb:5ME9|rcsb pdb:5MEA|rcsb pdb:5MEB|rcsb pdb:5MEC|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6WGG|rcsb pdb:6WGI dip:DIP-2408N|sgd:S000000406|refseq:NP_009761.4|mint:P38132|ensemblfungi:YBR202W(gene)|ensemblfungi:YBR202W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904931"(MCM complex binding)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGC|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 psi-mi:"MI:0469"(intact) crc64:099992C0E3CCA726 crc64:ADA66C719D96DB4A figure legend:Fig. 1F|complex-properties:Forms globular particles, approximately 15 nm in diameter|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/16 2014/10/16 rogid:bhL1vrVCG3mbWsF2S5nRT+i5fqw559292 rogid:OJMt3vgMFg5we7rPkQSmkxbL1dA559292 intact-crc:E2AADFAAB554DCAD|rigid:oQX6ZELpFoTC2wCKzi+QS731NLk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47112 uniprotkb:P29469 intact:EBI-25503|uniprotkb:D6VWL7|ensemblfungi:YJR046W intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 psi-mi:cdt1_yeast(display_long)|uniprotkb:YJR046W(locus name)|uniprotkb:J1641(orf name)|uniprotkb:TAH11(gene name)|psi-mi:TAH11(display_short)|uniprotkb:CDT1(gene name synonym)|uniprotkb:SID2(gene name synonym)|uniprotkb:SIC1 indispensable protein 2(gene name synonym)|uniprotkb:Topoisomerase-A hypersensitive protein 11(gene name synonym) psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Remus et al. (2009) imex:IM-12106|pubmed:19896182 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479185|imex:IM-12106-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003807|refseq:NP_012580.1|dip:DIP-7948N|ensemblfungi:YJR046W(gene)|ensemblfungi:YJR046W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0051301"(cell division)|interpro:IPR032054|interpro:IPR038090|rcsb pdb:5ME9|rcsb pdb:5MEA|rcsb pdb:5MEB|rcsb pdb:5MEC|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6WGG|rcsb pdb:6WGI refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N psi-mi:"MI:0469"(intact) crc64:099992C0E3CCA726 crc64:F38FF682581B0EC0 figure legend:Fig. 1F|complex-properties:Forms globular particles, approximately 15 nm in diameter|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/16 2014/10/16 rogid:bhL1vrVCG3mbWsF2S5nRT+i5fqw559292 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 intact-crc:5099D5B12FB51AA0|rigid:oQX6ZELpFoTC2wCKzi+QS731NLk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47112 uniprotkb:P24279 intact:EBI-25503|uniprotkb:D6VWL7|ensemblfungi:YJR046W intact:EBI-10541|ensemblfungi:YEL032W|uniprotkb:D3DLL7 psi-mi:cdt1_yeast(display_long)|uniprotkb:YJR046W(locus name)|uniprotkb:J1641(orf name)|uniprotkb:TAH11(gene name)|psi-mi:TAH11(display_short)|uniprotkb:CDT1(gene name synonym)|uniprotkb:SID2(gene name synonym)|uniprotkb:SIC1 indispensable protein 2(gene name synonym)|uniprotkb:Topoisomerase-A hypersensitive protein 11(gene name synonym) psi-mi:mcm3_yeast(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:YEL032W(locus name)|uniprotkb:SYGP-ORF23(orf name)|uniprotkb:Minichromosome maintenance protein 3(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Remus et al. (2009) imex:IM-12106|pubmed:19896182 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479185|imex:IM-12106-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003807|refseq:NP_012580.1|dip:DIP-7948N|ensemblfungi:YJR046W(gene)|ensemblfungi:YJR046W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0051301"(cell division)|interpro:IPR032054|interpro:IPR038090|rcsb pdb:5ME9|rcsb pdb:5MEA|rcsb pdb:5MEB|rcsb pdb:5MEC|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6WGG|rcsb pdb:6WGI refseq:NP_010882.1|sgd:S000000758|go:"GO:0005524"(ATP binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1904931"(MCM complex binding)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGC|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:5XF8|ensemblfungi:YEL032W(gene)|ensemblfungi:YEL032W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|mint:P24279|dip:DIP-2407N psi-mi:"MI:0469"(intact) crc64:099992C0E3CCA726 crc64:43DD4DACAF4456DC figure legend:Fig. 1F|complex-properties:Forms globular particles, approximately 15 nm in diameter|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/16 2014/10/16 rogid:bhL1vrVCG3mbWsF2S5nRT+i5fqw559292 rogid:OsFbdaTeE1vPQObriGt5M6mTPzk559292 intact-crc:5099D5B12FB51AA0|rigid:oQX6ZELpFoTC2wCKzi+QS731NLk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47112 uniprotkb:P30665 intact:EBI-25503|uniprotkb:D6VWL7|ensemblfungi:YJR046W intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W psi-mi:cdt1_yeast(display_long)|uniprotkb:YJR046W(locus name)|uniprotkb:J1641(orf name)|uniprotkb:TAH11(gene name)|psi-mi:TAH11(display_short)|uniprotkb:CDT1(gene name synonym)|uniprotkb:SID2(gene name synonym)|uniprotkb:SIC1 indispensable protein 2(gene name synonym)|uniprotkb:Topoisomerase-A hypersensitive protein 11(gene name synonym) psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Remus et al. (2009) imex:IM-12106|pubmed:19896182 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479185|imex:IM-12106-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003807|refseq:NP_012580.1|dip:DIP-7948N|ensemblfungi:YJR046W(gene)|ensemblfungi:YJR046W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0051301"(cell division)|interpro:IPR032054|interpro:IPR038090|rcsb pdb:5ME9|rcsb pdb:5MEA|rcsb pdb:5MEB|rcsb pdb:5MEC|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6WGG|rcsb pdb:6WGI dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 psi-mi:"MI:0469"(intact) crc64:099992C0E3CCA726 crc64:382D542AE38975E3 figure legend:Fig. 1F|complex-properties:Forms globular particles, approximately 15 nm in diameter|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/16 2014/10/16 rogid:bhL1vrVCG3mbWsF2S5nRT+i5fqw559292 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 intact-crc:5099D5B12FB51AA0|rigid:oQX6ZELpFoTC2wCKzi+QS731NLk false - flag tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47112 uniprotkb:P29496 intact:EBI-25503|uniprotkb:D6VWL7|ensemblfungi:YJR046W intact:EBI-10549|ensemblfungi:YLR274W|uniprotkb:D6VYS1 psi-mi:cdt1_yeast(display_long)|uniprotkb:YJR046W(locus name)|uniprotkb:J1641(orf name)|uniprotkb:TAH11(gene name)|psi-mi:TAH11(display_short)|uniprotkb:CDT1(gene name synonym)|uniprotkb:SID2(gene name synonym)|uniprotkb:SIC1 indispensable protein 2(gene name synonym)|uniprotkb:Topoisomerase-A hypersensitive protein 11(gene name synonym) psi-mi:mcm5_yeast(display_long)|uniprotkb:MCM5(gene name)|psi-mi:MCM5(display_short)|uniprotkb:CDC46(gene name synonym)|uniprotkb:YLR274W(locus name)|uniprotkb:L9328.1(orf name)|uniprotkb:Cell division control protein 46(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Remus et al. (2009) imex:IM-12106|pubmed:19896182 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479185|imex:IM-12106-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003807|refseq:NP_012580.1|dip:DIP-7948N|ensemblfungi:YJR046W(gene)|ensemblfungi:YJR046W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0051301"(cell division)|interpro:IPR032054|interpro:IPR038090|rcsb pdb:5ME9|rcsb pdb:5MEA|rcsb pdb:5MEB|rcsb pdb:5MEC|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6WGG|rcsb pdb:6WGI refseq:NP_013376.1|sgd:S000004264|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:3JC5|rcsb pdb:6WGG|rcsb pdb:6WGI|ensemblfungi:YLR274W(gene)|ensemblfungi:YLR274W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|reactome:R-SCE-68949|reactome:R-SCE-69052|reactome:R-SCE-68962|dip:DIP-2406N psi-mi:"MI:0469"(intact) crc64:099992C0E3CCA726 crc64:01D9DE208A091CF2 figure legend:Fig. 1F|complex-properties:Forms globular particles, approximately 15 nm in diameter|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/16 2014/10/16 rogid:bhL1vrVCG3mbWsF2S5nRT+i5fqw559292 rogid:a8UgYOklJ5vWqhA0hbQTCWNQg0Y559292 intact-crc:5099D5B12FB51AA0|rigid:oQX6ZELpFoTC2wCKzi+QS731NLk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47112 uniprotkb:P53091 intact:EBI-25503|uniprotkb:D6VWL7|ensemblfungi:YJR046W intact:EBI-10556|uniprotkb:Q870M9|ensemblfungi:YGL201C|uniprotkb:D6VTV3 psi-mi:cdt1_yeast(display_long)|uniprotkb:YJR046W(locus name)|uniprotkb:J1641(orf name)|uniprotkb:TAH11(gene name)|psi-mi:TAH11(display_short)|uniprotkb:CDT1(gene name synonym)|uniprotkb:SID2(gene name synonym)|uniprotkb:SIC1 indispensable protein 2(gene name synonym)|uniprotkb:Topoisomerase-A hypersensitive protein 11(gene name synonym) psi-mi:mcm6_yeast(display_long)|uniprotkb:YGL201C(locus name)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:Minichromosome maintenance protein 6(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Remus et al. (2009) imex:IM-12106|pubmed:19896182 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479185|imex:IM-12106-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003807|refseq:NP_012580.1|dip:DIP-7948N|ensemblfungi:YJR046W(gene)|ensemblfungi:YJR046W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0051301"(cell division)|interpro:IPR032054|interpro:IPR038090|rcsb pdb:5ME9|rcsb pdb:5MEA|rcsb pdb:5MEB|rcsb pdb:5MEC|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6WGG|rcsb pdb:6WGI ensemblfungi:YGL201C(gene)|refseq:NP_011314.2|sgd:S000003169|ensemblfungi:YGL201C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:5V8F|mint:P53091|dip:DIP-1294N psi-mi:"MI:0469"(intact) crc64:099992C0E3CCA726 crc64:03AB793134E64A50 figure legend:Fig. 1F|complex-properties:Forms globular particles, approximately 15 nm in diameter|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/16 2014/10/16 rogid:bhL1vrVCG3mbWsF2S5nRT+i5fqw559292 rogid:b2Pak0d6eENHIzSFaBge/kPQceU559292 intact-crc:5099D5B12FB51AA0|rigid:oQX6ZELpFoTC2wCKzi+QS731NLk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47112 uniprotkb:P38132 intact:EBI-25503|uniprotkb:D6VWL7|ensemblfungi:YJR046W intact:EBI-4300|uniprotkb:D6VQK0|ensemblfungi:YBR202W psi-mi:cdt1_yeast(display_long)|uniprotkb:YJR046W(locus name)|uniprotkb:J1641(orf name)|uniprotkb:TAH11(gene name)|psi-mi:TAH11(display_short)|uniprotkb:CDT1(gene name synonym)|uniprotkb:SID2(gene name synonym)|uniprotkb:SIC1 indispensable protein 2(gene name synonym)|uniprotkb:Topoisomerase-A hypersensitive protein 11(gene name synonym) psi-mi:mcm7_yeast(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:YBR202W(locus name)|uniprotkb:YBR1441(orf name)|uniprotkb:CDC47(gene name synonym)|uniprotkb:Cell division control protein 47(gene name synonym)|uniprotkb:Minichromosome maintenance protein 7(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Remus et al. (2009) imex:IM-12106|pubmed:19896182 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479185|imex:IM-12106-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003807|refseq:NP_012580.1|dip:DIP-7948N|ensemblfungi:YJR046W(gene)|ensemblfungi:YJR046W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0051301"(cell division)|interpro:IPR032054|interpro:IPR038090|rcsb pdb:5ME9|rcsb pdb:5MEA|rcsb pdb:5MEB|rcsb pdb:5MEC|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6WGG|rcsb pdb:6WGI dip:DIP-2408N|sgd:S000000406|refseq:NP_009761.4|mint:P38132|ensemblfungi:YBR202W(gene)|ensemblfungi:YBR202W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904931"(MCM complex binding)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGC|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 psi-mi:"MI:0469"(intact) crc64:099992C0E3CCA726 crc64:ADA66C719D96DB4A figure legend:Fig. 1F|complex-properties:Forms globular particles, approximately 15 nm in diameter|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/16 2014/10/16 rogid:bhL1vrVCG3mbWsF2S5nRT+i5fqw559292 rogid:OJMt3vgMFg5we7rPkQSmkxbL1dA559292 intact-crc:5099D5B12FB51AA0|rigid:oQX6ZELpFoTC2wCKzi+QS731NLk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)