#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q92544	uniprotkb:P20339	intact:EBI-6138615|uniprotkb:B0QYT7|uniprotkb:Q9NUA3|ensembl:ENSP00000381104	intact:EBI-399437|uniprotkb:B4DJA5|intact:EBI-1048179|uniprotkb:Q6FI44|ensembl:ENSP00000273047	psi-mi:tm9s4_human(display_long)|uniprotkb:TM9SF4(gene name)|psi-mi:TM9SF4(display_short)|uniprotkb:KIAA0255(gene name synonym)|uniprotkb:TUCAP1(gene name synonym)|uniprotkb:Tumor cannibalism associated protein 1(gene name synonym)	psi-mi:rab5a_human(display_long)|uniprotkb:RAB5A(gene name)|psi-mi:RAB5A(display_short)|uniprotkb:RAB5(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Lozupone et al. (2009)	pubmed:19893578|imex:IM-15541|mint:MINT-7307305|doi:10.1038/embor.2009.236	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7578845|mint:MINT-7307320|imex:IM-15541-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055557.2|refseq:XP_005260679.1|ensembl:ENSG00000101337(gene)|ensembl:ENST00000398022(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006909"(phagocytosis)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0072657"(protein localization to membrane)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR004240("Nonaspanin (TM9SF)")|mint:Q92544|mint:MINT-7307323(identity)	refseq:NP_004153.2|refseq:NP_001278977.1|dip:DIP-380N|ensembl:ENSG00000144566(gene)|ensembl:ENST00000273047(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043679"(axon terminus)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0051036"(regulation of endosome size)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098559"(cytoplasmic side of early endosome membrane)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:2000286"(receptor internalization involved in canonical Wnt signaling pathway)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P20339|rcsb pdb:1N6H|rcsb pdb:1N6I|rcsb pdb:1N6K|rcsb pdb:1N6L|rcsb pdb:1N6N|rcsb pdb:1N6O|rcsb pdb:1N6P|rcsb pdb:1N6R|rcsb pdb:1R2Q|rcsb pdb:1TU3|rcsb pdb:1TU4|rcsb pdb:3MJH|rcsb pdb:4Q9U|rcsb pdb:7BL1|reactome:R-HSA-1660499|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9636383|reactome:R-HSA-983231|mint:MINT-7307322(identity)	go:"GO:0005764"(lysosome)	-	-	figure legend:f3a|comment:homomint|comment:mint|comment:The same pattern of co-localization has been verified in MM2 cells.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mm1)|taxid:9606(Homo sapiens)	-	2009/12/02	2014/10/16	rogid:fyUWoncGmCxUAMx15iApsIcXdCI9606	rogid:SgowwV7QSVCvfsqSDE+6CHmPmKA9606	intact-crc:8D736F4D898266EE|rigid:U/1yldUF6bKb3Aa2bw8euO621DE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P20339	uniprotkb:Q92544	intact:EBI-399437|uniprotkb:B4DJA5|intact:EBI-1048179|uniprotkb:Q6FI44|ensembl:ENSP00000273047	intact:EBI-6138615|uniprotkb:B0QYT7|uniprotkb:Q9NUA3|ensembl:ENSP00000381104	psi-mi:rab5a_human(display_long)|uniprotkb:RAB5A(gene name)|psi-mi:RAB5A(display_short)|uniprotkb:RAB5(gene name synonym)	psi-mi:tm9s4_human(display_long)|uniprotkb:TM9SF4(gene name)|psi-mi:TM9SF4(display_short)|uniprotkb:KIAA0255(gene name synonym)|uniprotkb:TUCAP1(gene name synonym)|uniprotkb:Tumor cannibalism associated protein 1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Lozupone et al. (2009)	pubmed:19893578|imex:IM-15541|mint:MINT-7307305|doi:10.1038/embor.2009.236	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7578953|mint:MINT-7307331|imex:IM-15541-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004153.2|refseq:NP_001278977.1|dip:DIP-380N|ensembl:ENSG00000144566(gene)|ensembl:ENST00000273047(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043679"(axon terminus)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0051036"(regulation of endosome size)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098559"(cytoplasmic side of early endosome membrane)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:2000286"(receptor internalization involved in canonical Wnt signaling pathway)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P20339|rcsb pdb:1N6H|rcsb pdb:1N6I|rcsb pdb:1N6K|rcsb pdb:1N6L|rcsb pdb:1N6N|rcsb pdb:1N6O|rcsb pdb:1N6P|rcsb pdb:1N6R|rcsb pdb:1R2Q|rcsb pdb:1TU3|rcsb pdb:1TU4|rcsb pdb:3MJH|rcsb pdb:4Q9U|rcsb pdb:7BL1|reactome:R-HSA-1660499|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9636383|reactome:R-HSA-983231|mint:MINT-7307336(identity)	refseq:NP_055557.2|refseq:XP_005260679.1|ensembl:ENSG00000101337(gene)|ensembl:ENST00000398022(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006909"(phagocytosis)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0072657"(protein localization to membrane)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR004240("Nonaspanin (TM9SF)")|mint:Q92544|mint:MINT-7307334(identity)	go:"GO:0005764"(lysosome)	-	-	figure legend:f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mm2)|taxid:9606(Homo sapiens)	-	2009/12/02	2014/10/16	rogid:SgowwV7QSVCvfsqSDE+6CHmPmKA9606	rogid:fyUWoncGmCxUAMx15iApsIcXdCI9606	intact-crc:740FF4F3AF5709F3|rigid:U/1yldUF6bKb3Aa2bw8euO621DE	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)