#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q0IHI4 uniprotkb:O13046 intact:EBI-7570880|intact:MINT-7386201|uniprotkb:Q3LGB8 intact:EBI-3510652 psi-mi:tipin_xenla(display_long)|uniprotkb:tipin(gene name)|psi-mi:tipin(display_short)|uniprotkb:XTipin(gene name synonym) psi-mi:wdhd1_xenla(display_long)|uniprotkb:Acidic nucleoplasmic DNA-binding protein 1(gene name synonym)|uniprotkb:wdhd1(gene name)|psi-mi:wdhd1(display_short) psi-mi:"MI:0019"(coimmunoprecipitation) Errico et al. (2009) pubmed:19893489|imex:IM-13896|mint:MINT-7386195|doi:10.1038/emboj.2009.304 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7570905|mint:MINT-7386324|imex:IM-13896-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q0IHI4|refseq:NP_001081090.1|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|interpro:IPR012923(Replication fork protection component Swi3)|interpro:IPR040038|dip:DIP-46439N|mint:MINT-7386326(identity) interpro:IPR036322|interpro:IPR036910|mint:O13046|interpro:IPR022100|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|mint:MINT-7386327(identity) - comment:mint - figure legend:f4a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla-)|taxid:8355(Xenopus laevis) - 2009/12/23 2014/10/16 rogid:ZqZ/cwegOp6asrESHKMF7FH4RzQ8355 rogid:GqDkIeSLFGdHLJvzMgxS7S6Bc6M8355 intact-crc:505098E8E021CA6C|rigid:9LjCkEIiq8jVRyanw6L6XQ2/L8U false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q0IHI4 uniprotkb:Q9DE46 intact:EBI-7570880|intact:MINT-7386201|uniprotkb:Q3LGB8 intact:EBI-3645423 psi-mi:tipin_xenla(display_long)|uniprotkb:tipin(gene name)|psi-mi:tipin(display_short)|uniprotkb:XTipin(gene name synonym) psi-mi:dpola_xenla(display_long)|uniprotkb:pola1(gene name)|psi-mi:pola1(display_short)|uniprotkb:pola(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Errico et al. (2009) pubmed:19893489|imex:IM-13896|mint:MINT-7386195|doi:10.1038/emboj.2009.304 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7570875|mint:MINT-7386251|imex:IM-13896-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q0IHI4|refseq:NP_001081090.1|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|interpro:IPR012923(Replication fork protection component Swi3)|interpro:IPR040038|dip:DIP-46439N|mint:MINT-7386253(identity) interpro:IPR036397|mint:Q9DE46|refseq:NP_001082055.1|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR017964|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR024647|interpro:IPR023211|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR038256|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0016363"(nuclear matrix)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR042087|interpro:IPR043502|mint:MINT-7386254(identity) - comment:mint - figure legend:f2a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla-)|taxid:8355(Xenopus laevis) - 2009/12/23 2014/10/16 rogid:ZqZ/cwegOp6asrESHKMF7FH4RzQ8355 rogid:+qjNlZXAOs+OkptTbRTMuLUZh5s8355 intact-crc:70FEBEAE583D856C|rigid:WZNMBcMGplLFULEPs6799wKmvTg false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O13046 uniprotkb:Q0IHI4 intact:EBI-3510652 intact:EBI-7570880|intact:MINT-7386201|uniprotkb:Q3LGB8 psi-mi:wdhd1_xenla(display_long)|uniprotkb:Acidic nucleoplasmic DNA-binding protein 1(gene name synonym)|uniprotkb:wdhd1(gene name)|psi-mi:wdhd1(display_short) psi-mi:tipin_xenla(display_long)|uniprotkb:tipin(gene name)|psi-mi:tipin(display_short)|uniprotkb:XTipin(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Errico et al. (2009) pubmed:19893489|imex:IM-13896|mint:MINT-7386195|doi:10.1038/emboj.2009.304 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7570944|mint:MINT-7500675|imex:IM-13896-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036322|interpro:IPR036910|mint:O13046|interpro:IPR022100|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|mint:MINT-7500678(identity) mint:Q0IHI4|refseq:NP_001081090.1|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|interpro:IPR012923(Replication fork protection component Swi3)|interpro:IPR040038|dip:DIP-46439N|mint:MINT-7500677(identity) go:"GO:0005634"(nucleus) - comment:mint comment:mint|figure legend:fs2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla-)|taxid:8355(Xenopus laevis) - 2009/12/23 2014/10/16 rogid:GqDkIeSLFGdHLJvzMgxS7S6Bc6M8355 rogid:ZqZ/cwegOp6asrESHKMF7FH4RzQ8355 intact-crc:48A014459C2CB0D2|rigid:WWPy67FLyyxt1S9K/4j6iu6tUUI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O13046 uniprotkb:Q9DE46 intact:EBI-3510652 intact:EBI-3645423 psi-mi:wdhd1_xenla(display_long)|uniprotkb:Acidic nucleoplasmic DNA-binding protein 1(gene name synonym)|uniprotkb:wdhd1(gene name)|psi-mi:wdhd1(display_short) psi-mi:dpola_xenla(display_long)|uniprotkb:pola1(gene name)|psi-mi:pola1(display_short)|uniprotkb:pola(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Errico et al. (2009) pubmed:19893489|imex:IM-13896|mint:MINT-7386195|doi:10.1038/emboj.2009.304 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7570944|mint:MINT-7500675|imex:IM-13896-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036322|interpro:IPR036910|mint:O13046|interpro:IPR022100|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|mint:MINT-7500678(identity) interpro:IPR036397|mint:Q9DE46|refseq:NP_001082055.1|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR017964|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR024647|interpro:IPR023211|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR038256|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0016363"(nuclear matrix)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR042087|interpro:IPR043502|mint:MINT-7500768(identity) go:"GO:0005634"(nucleus) - - comment:mint|figure legend:fs2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla-)|taxid:8355(Xenopus laevis) - 2009/12/23 2014/10/16 rogid:GqDkIeSLFGdHLJvzMgxS7S6Bc6M8355 rogid:+qjNlZXAOs+OkptTbRTMuLUZh5s8355 intact-crc:48A014459C2CB0D2|rigid:WWPy67FLyyxt1S9K/4j6iu6tUUI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q0IHI4 uniprotkb:Q9DE46 intact:EBI-7570880|intact:MINT-7386201|uniprotkb:Q3LGB8 intact:EBI-3645423 psi-mi:tipin_xenla(display_long)|uniprotkb:tipin(gene name)|psi-mi:tipin(display_short)|uniprotkb:XTipin(gene name synonym) psi-mi:dpola_xenla(display_long)|uniprotkb:pola1(gene name)|psi-mi:pola1(display_short)|uniprotkb:pola(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Errico et al. (2009) pubmed:19893489|imex:IM-13896|mint:MINT-7386195|doi:10.1038/emboj.2009.304 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7570960|mint:MINT-7500780|imex:IM-13896-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q0IHI4|refseq:NP_001081090.1|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|interpro:IPR012923(Replication fork protection component Swi3)|interpro:IPR040038|dip:DIP-46439N|mint:MINT-7500787(identity) interpro:IPR036397|mint:Q9DE46|refseq:NP_001082055.1|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR017964|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR024647|interpro:IPR023211|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR038256|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0016363"(nuclear matrix)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR042087|interpro:IPR043502|mint:MINT-7500783(identity) go:"GO:0005634"(nucleus) comment:mint - comment:mint|figure legend:fs2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla-)|taxid:8355(Xenopus laevis) - 2009/12/23 2014/10/16 rogid:ZqZ/cwegOp6asrESHKMF7FH4RzQ8355 rogid:+qjNlZXAOs+OkptTbRTMuLUZh5s8355 intact-crc:0C1ED3E8C2E1E92B|rigid:WWPy67FLyyxt1S9K/4j6iu6tUUI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q0IHI4 uniprotkb:O13046 intact:EBI-7570880|intact:MINT-7386201|uniprotkb:Q3LGB8 intact:EBI-3510652 psi-mi:tipin_xenla(display_long)|uniprotkb:tipin(gene name)|psi-mi:tipin(display_short)|uniprotkb:XTipin(gene name synonym) psi-mi:wdhd1_xenla(display_long)|uniprotkb:Acidic nucleoplasmic DNA-binding protein 1(gene name synonym)|uniprotkb:wdhd1(gene name)|psi-mi:wdhd1(display_short) psi-mi:"MI:0019"(coimmunoprecipitation) Errico et al. (2009) pubmed:19893489|imex:IM-13896|mint:MINT-7386195|doi:10.1038/emboj.2009.304 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7570960|mint:MINT-7500780|imex:IM-13896-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q0IHI4|refseq:NP_001081090.1|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|interpro:IPR012923(Replication fork protection component Swi3)|interpro:IPR040038|dip:DIP-46439N|mint:MINT-7500787(identity) interpro:IPR036322|interpro:IPR036910|mint:O13046|interpro:IPR022100|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|mint:MINT-7500785(identity) go:"GO:0005634"(nucleus) comment:mint - comment:mint|figure legend:fs2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla-)|taxid:8355(Xenopus laevis) - 2009/12/23 2014/10/16 rogid:ZqZ/cwegOp6asrESHKMF7FH4RzQ8355 rogid:GqDkIeSLFGdHLJvzMgxS7S6Bc6M8355 intact-crc:0C1ED3E8C2E1E92B|rigid:WWPy67FLyyxt1S9K/4j6iu6tUUI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q0IHI4 uniprotkb:O13046 intact:EBI-7570880|intact:MINT-7386201|uniprotkb:Q3LGB8 intact:EBI-3510652 psi-mi:tipin_xenla(display_long)|uniprotkb:tipin(gene name)|psi-mi:tipin(display_short)|uniprotkb:XTipin(gene name synonym) psi-mi:wdhd1_xenla(display_long)|uniprotkb:Acidic nucleoplasmic DNA-binding protein 1(gene name synonym)|uniprotkb:wdhd1(gene name)|psi-mi:wdhd1(display_short) psi-mi:"MI:0019"(coimmunoprecipitation) Errico et al. (2009) pubmed:19893489|imex:IM-13896|mint:MINT-7386195|doi:10.1038/emboj.2009.304 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7570933|mint:MINT-7386346|imex:IM-13896-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q0IHI4|refseq:NP_001081090.1|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|interpro:IPR012923(Replication fork protection component Swi3)|interpro:IPR040038|dip:DIP-46439N|mint:MINT-7386350(identity) interpro:IPR036322|interpro:IPR036910|mint:O13046|interpro:IPR022100|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|mint:MINT-7386348(identity) - comment:mint - figure legend:f4a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla-)|taxid:8355(Xenopus laevis) - 2009/12/23 2014/10/16 rogid:ZqZ/cwegOp6asrESHKMF7FH4RzQ8355 rogid:GqDkIeSLFGdHLJvzMgxS7S6Bc6M8355 intact-crc:B0532B7EE027EEC6|rigid:9LjCkEIiq8jVRyanw6L6XQ2/L8U false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q0IHI4 uniprotkb:O13046 intact:EBI-7570880|intact:MINT-7386201|uniprotkb:Q3LGB8 intact:EBI-3510652 psi-mi:tipin_xenla(display_long)|uniprotkb:tipin(gene name)|psi-mi:tipin(display_short)|uniprotkb:XTipin(gene name synonym) psi-mi:wdhd1_xenla(display_long)|uniprotkb:Acidic nucleoplasmic DNA-binding protein 1(gene name synonym)|uniprotkb:wdhd1(gene name)|psi-mi:wdhd1(display_short) psi-mi:"MI:0096"(pull down) Errico et al. (2009) pubmed:19893489|imex:IM-13896|mint:MINT-7386195|doi:10.1038/emboj.2009.304 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7571003|mint:MINT-7386423|imex:IM-13896-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q0IHI4|refseq:NP_001081090.1|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|interpro:IPR012923(Replication fork protection component Swi3)|interpro:IPR040038|dip:DIP-46439N|mint:MINT-7386425(identity) interpro:IPR036322|interpro:IPR036910|mint:O13046|interpro:IPR022100|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|mint:MINT-7386426(identity) - comment:mint - figure legend:f4b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/23 2014/10/16 rogid:ZqZ/cwegOp6asrESHKMF7FH4RzQ8355 rogid:GqDkIeSLFGdHLJvzMgxS7S6Bc6M8355 intact-crc:86C5D368C9870D07|rigid:9LjCkEIiq8jVRyanw6L6XQ2/L8U false his tag:?-?(MINT-7386444) - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q0IHI4 uniprotkb:Q9DE46 intact:EBI-7570880|intact:MINT-7386201|uniprotkb:Q3LGB8 intact:EBI-3645423 psi-mi:tipin_xenla(display_long)|uniprotkb:tipin(gene name)|psi-mi:tipin(display_short)|uniprotkb:XTipin(gene name synonym) psi-mi:dpola_xenla(display_long)|uniprotkb:pola1(gene name)|psi-mi:pola1(display_short)|uniprotkb:pola(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym) psi-mi:"MI:0096"(pull down) Errico et al. (2009) pubmed:19893489|imex:IM-13896|mint:MINT-7386195|doi:10.1038/emboj.2009.304 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7571031|mint:MINT-7386532|imex:IM-13896-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q0IHI4|refseq:NP_001081090.1|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|interpro:IPR012923(Replication fork protection component Swi3)|interpro:IPR040038|dip:DIP-46439N|mint:MINT-7386541(identity) interpro:IPR036397|mint:Q9DE46|refseq:NP_001082055.1|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR017964|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR024647|interpro:IPR023211|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR038256|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0016363"(nuclear matrix)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR042087|interpro:IPR043502|mint:MINT-7386534(identity) - comment:mint - figure legend:f4c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/23 2014/10/16 rogid:ZqZ/cwegOp6asrESHKMF7FH4RzQ8355 rogid:+qjNlZXAOs+OkptTbRTMuLUZh5s8355 intact-crc:8DD6AE7A9BCBE61D|rigid:WZNMBcMGplLFULEPs6799wKmvTg false glutathione s tranferase tag:?-?(MINT-7386546) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:O13046 uniprotkb:Q9DE46 intact:EBI-3510652 intact:EBI-3645423 psi-mi:wdhd1_xenla(display_long)|uniprotkb:Acidic nucleoplasmic DNA-binding protein 1(gene name synonym)|uniprotkb:wdhd1(gene name)|psi-mi:wdhd1(display_short) psi-mi:dpola_xenla(display_long)|uniprotkb:pola1(gene name)|psi-mi:pola1(display_short)|uniprotkb:pola(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym) psi-mi:"MI:0096"(pull down) Errico et al. (2009) pubmed:19893489|imex:IM-13896|mint:MINT-7386195|doi:10.1038/emboj.2009.304 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7571017|mint:MINT-7386475|imex:IM-13896-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036322|interpro:IPR036910|mint:O13046|interpro:IPR022100|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|mint:MINT-7386477(identity) interpro:IPR036397|mint:Q9DE46|refseq:NP_001082055.1|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR017964|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR024647|interpro:IPR023211|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR038256|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0016363"(nuclear matrix)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR042087|interpro:IPR043502|mint:MINT-7386479(identity) - - - figure legend:f4c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/23 2014/10/16 rogid:GqDkIeSLFGdHLJvzMgxS7S6Bc6M8355 rogid:+qjNlZXAOs+OkptTbRTMuLUZh5s8355 intact-crc:78311FB51F5BAF8A|rigid:KOfQGSSJ7dhje3R67TPyvgYTqA4 false glutathione s tranferase tag:?-?(MINT-7386528) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)