#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P46948	uniprotkb:Q08162	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	intact:EBI-1740|uniprotkb:D6W244|ensemblfungi:YOL021C	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:rrp44_yeast(display_long)|uniprotkb:DIS3(gene name)|psi-mi:DIS3(display_short)|uniprotkb:Ribosomal RNA-processing protein 44(gene name synonym)|uniprotkb:Chromosome disjunction protein 3(gene name synonym)|uniprotkb:RRP44(gene name synonym)|uniprotkb:O2197(orf name)|uniprotkb:YOL021C(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Bonneau et al. (2009)	imex:IM-12105|pubmed:19879841	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2478789|wwpdb:2wp8|imex:IM-12105-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	sgd:S000005381|refseq:NP_014621.1|dip:DIP-2355N|mint:Q08162|ensemblfungi:YOL021C(gene)|ensemblfungi:YOL021C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR003029(S1, RNA binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR022967|interpro:IPR029060|interpro:IPR033770|interpro:IPR033771|interpro:IPR041505|rcsb pdb:2VNU|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513	-	crc64:C80EFFB528A43044	crc64:00DD31BD2D6904F4	3d-resolution:3.0A|3d-r-factors:"R-factor: 20.899%, Free R-factor: 27.291%"|figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/11/12	2014/10/16	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	rogid:YpToZNRenOPYsPJdGKEWBLsc4zA559292	intact-crc:0764764C6667DE60|rigid:xP4Hea/sLD9xTTgUzAOwCMPd+ho	false	-	sufficient binding region:25-1001	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46948	uniprotkb:Q05636	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	intact:EBI-1810|uniprotkb:D6VSR0|ensemblfungi:YDR280W	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:rrp45_yeast(display_long)|uniprotkb:RRP45(gene name)|psi-mi:RRP45(display_short)|uniprotkb:YDR280W(locus name)|uniprotkb:D9954.1(orf name)|uniprotkb:Ribosomal RNA-processing protein 45(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Bonneau et al. (2009)	imex:IM-12105|pubmed:19879841	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2478789|wwpdb:2wp8|imex:IM-12105-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	refseq:NP_010566.1|sgd:S000002688|dip:DIP-2084N|mint:Q05636|ensemblfungi:YDR280W(gene)|ensemblfungi:YDR280W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	-	crc64:C80EFFB528A43044	crc64:65C9DB5A63678F2D	3d-resolution:3.0A|3d-r-factors:"R-factor: 20.899%, Free R-factor: 27.291%"|figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/11/12	2014/10/16	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	rogid:LCdt9Nm8j2AD6iecBI2CGCrhEhQ559292	intact-crc:0764764C6667DE60|rigid:xP4Hea/sLD9xTTgUzAOwCMPd+ho	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46948	uniprotkb:Q08162	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	intact:EBI-1740|uniprotkb:D6W244|ensemblfungi:YOL021C	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:rrp44_yeast(display_long)|uniprotkb:DIS3(gene name)|psi-mi:DIS3(display_short)|uniprotkb:Ribosomal RNA-processing protein 44(gene name synonym)|uniprotkb:Chromosome disjunction protein 3(gene name synonym)|uniprotkb:RRP44(gene name synonym)|uniprotkb:O2197(orf name)|uniprotkb:YOL021C(locus name)	psi-mi:"MI:0096"(pull down)	Bonneau et al. (2009)	imex:IM-12105|pubmed:19879841	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2478806|imex:IM-12105-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	sgd:S000005381|refseq:NP_014621.1|dip:DIP-2355N|mint:Q08162|ensemblfungi:YOL021C(gene)|ensemblfungi:YOL021C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR003029(S1, RNA binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR022967|interpro:IPR029060|interpro:IPR033770|interpro:IPR033771|interpro:IPR041505|rcsb pdb:2VNU|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513	psi-mi:"MI:0469"(intact)	crc64:C80EFFB528A43044	crc64:00DD31BD2D6904F4	figure legend:Supp. Fig. 4A, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/11/12	2014/10/16	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	rogid:YpToZNRenOPYsPJdGKEWBLsc4zA559292	intact-crc:66D6434BB2AF815C|rigid:xP4Hea/sLD9xTTgUzAOwCMPd+ho	false	calmodulin binding protein tag:?-?	sufficient binding region:25-1001	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P46948	uniprotkb:Q05636	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	intact:EBI-1810|uniprotkb:D6VSR0|ensemblfungi:YDR280W	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:rrp45_yeast(display_long)|uniprotkb:RRP45(gene name)|psi-mi:RRP45(display_short)|uniprotkb:YDR280W(locus name)|uniprotkb:D9954.1(orf name)|uniprotkb:Ribosomal RNA-processing protein 45(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bonneau et al. (2009)	imex:IM-12105|pubmed:19879841	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2478806|imex:IM-12105-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	refseq:NP_010566.1|sgd:S000002688|dip:DIP-2084N|mint:Q05636|ensemblfungi:YDR280W(gene)|ensemblfungi:YDR280W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	psi-mi:"MI:0469"(intact)	crc64:C80EFFB528A43044	crc64:65C9DB5A63678F2D	figure legend:Supp. Fig. 4A, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/11/12	2014/10/16	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	rogid:LCdt9Nm8j2AD6iecBI2CGCrhEhQ559292	intact-crc:66D6434BB2AF815C|rigid:xP4Hea/sLD9xTTgUzAOwCMPd+ho	false	calmodulin binding protein tag:?-?	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P46948	uniprotkb:Q08162	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	intact:EBI-1740|uniprotkb:D6W244|ensemblfungi:YOL021C	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:rrp44_yeast(display_long)|uniprotkb:DIS3(gene name)|psi-mi:DIS3(display_short)|uniprotkb:Ribosomal RNA-processing protein 44(gene name synonym)|uniprotkb:Chromosome disjunction protein 3(gene name synonym)|uniprotkb:RRP44(gene name synonym)|uniprotkb:O2197(orf name)|uniprotkb:YOL021C(locus name)	psi-mi:"MI:0071"(molecular sieving)	Bonneau et al. (2009)	imex:IM-12105|pubmed:19879841	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2478825|imex:IM-12105-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	sgd:S000005381|refseq:NP_014621.1|dip:DIP-2355N|mint:Q08162|ensemblfungi:YOL021C(gene)|ensemblfungi:YOL021C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR003029(S1, RNA binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR022967|interpro:IPR029060|interpro:IPR033770|interpro:IPR033771|interpro:IPR041505|rcsb pdb:2VNU|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513	psi-mi:"MI:0469"(intact)	crc64:C80EFFB528A43044	crc64:00DD31BD2D6904F4	figure legend:Supp. Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/11/12	2014/10/16	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	rogid:YpToZNRenOPYsPJdGKEWBLsc4zA559292	intact-crc:D683DD1059A002EC|rigid:xP4Hea/sLD9xTTgUzAOwCMPd+ho	false	-	sufficient binding region:25-1001	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P46948	uniprotkb:Q05636	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	intact:EBI-1810|uniprotkb:D6VSR0|ensemblfungi:YDR280W	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:rrp45_yeast(display_long)|uniprotkb:RRP45(gene name)|psi-mi:RRP45(display_short)|uniprotkb:YDR280W(locus name)|uniprotkb:D9954.1(orf name)|uniprotkb:Ribosomal RNA-processing protein 45(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Bonneau et al. (2009)	imex:IM-12105|pubmed:19879841	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2478825|imex:IM-12105-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	refseq:NP_010566.1|sgd:S000002688|dip:DIP-2084N|mint:Q05636|ensemblfungi:YDR280W(gene)|ensemblfungi:YDR280W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	psi-mi:"MI:0469"(intact)	crc64:C80EFFB528A43044	crc64:65C9DB5A63678F2D	figure legend:Supp. Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/11/12	2014/10/16	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	rogid:LCdt9Nm8j2AD6iecBI2CGCrhEhQ559292	intact-crc:D683DD1059A002EC|rigid:xP4Hea/sLD9xTTgUzAOwCMPd+ho	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)