#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B chebi:"CHEBI:16337" uniprotkb:Q9VK31 intact:EBI-1263288 intact:EBI-109009|ensemblmetazoa:FBpp0080016 psi-mi:phosphatidic acids(display_short)|psi-mi:"CHEBI:16337"(display_long) psi-mi:q9vk31_drome(display_long)|uniprotkb:Dmel_CG5439(orf name)|uniprotkb:CG5439(orf name)|uniprotkb:Dmel\CG5439(gene name)|psi-mi:Dmel\CG5439(display_short) psi-mi:"MI:0049"(filter binding) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2465284|imex:IM-12096-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_609607.1|flybase:FBgn0032476|ensemblmetazoa:FBgn0032476(gene)|ensemblmetazoa:FBtr0080435(transcript)|go:"GO:0035091"(phosphatidylinositol binding)|interpro:IPR001683(Phox-like)|interpro:IPR004012(RUN)|interpro:IPR036871|interpro:IPR037213|interpro:IPR037916 - - - figure legend:Fig. 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/21 2014/10/16 - rogid:uMRaI9JsdPFfyMfckD547FWzN887227 intact-crc:C786CF91E6AF1F61 false - 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) chebi:"CHEBI:17526" uniprotkb:Q06385 intact:EBI-2465282 intact:EBI-35395|uniprotkb:D6VT03|ensemblfungi:YDR372C psi-mi:pi4p(display_short)|psi-mi:"CHEBI:17526"(display_long) psi-mi:vps74_yeast(display_long)|uniprotkb:VPS74(gene name)|psi-mi:VPS74(display_short)|uniprotkb:D9481.15(orf name)|uniprotkb:YDR372C(locus name) psi-mi:"MI:0049"(filter binding) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2465352|imex:IM-12096-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_010660.1|sgd:S000002780|mint:Q06385|dip:DIP-1768N|ensemblfungi:YDR372C(gene)|ensemblfungi:YDR372C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261|rcsb pdb:2ZIH|rcsb pdb:2ZII|rcsb pdb:4TU3 - - crc64:9D111E5F894F3646 figure legend:Fig. 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/21 2014/10/16 - rogid:FG2r3/9HQo5OUtCcHLq3UtdtmjQ559292 intact-crc:ABE5A354B34D92B4 false - 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) chebi:"CHEBI:17283" uniprotkb:Q9VK31 intact:EBI-1257113 intact:EBI-109009|ensemblmetazoa:FBpp0080016 psi-mi:pi3p(display_short)|psi-mi:"CHEBI:17283"(display_long) psi-mi:q9vk31_drome(display_long)|uniprotkb:Dmel_CG5439(orf name)|uniprotkb:CG5439(orf name)|uniprotkb:Dmel\CG5439(gene name)|psi-mi:Dmel\CG5439(display_short) psi-mi:"MI:0049"(filter binding) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2465364|imex:IM-12096-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_609607.1|flybase:FBgn0032476|ensemblmetazoa:FBgn0032476(gene)|ensemblmetazoa:FBtr0080435(transcript)|go:"GO:0035091"(phosphatidylinositol binding)|interpro:IPR001683(Phox-like)|interpro:IPR004012(RUN)|interpro:IPR036871|interpro:IPR037213|interpro:IPR037916 - - - figure legend:Fig. 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/21 2014/10/16 - rogid:uMRaI9JsdPFfyMfckD547FWzN887227 intact-crc:092CDF526996FDCD false - 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) chebi:"CHEBI:17526" uniprotkb:Q9VQ93 intact:EBI-2465282 intact:EBI-84891|ensemblmetazoa:FBpp0100138|ensemblmetazoa:FBpp0100140|ensemblmetazoa:FBpp0100141 psi-mi:pi4p(display_short)|psi-mi:"CHEBI:17526"(display_long) psi-mi:golp3_drome(display_long)|uniprotkb:sau(gene name)|psi-mi:sau(display_short)|uniprotkb:GOLPH3(gene name synonym)|uniprotkb:Protein rotini(gene name synonym)|uniprotkb:"l(2)s5379"(gene name synonym)|uniprotkb:rti(gene name synonym)|uniprotkb:CG7085(orf name) psi-mi:"MI:0049"(filter binding) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2465380|imex:IM-12096-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - flybase:FBgn0267378|refseq:NP_001014460.1|refseq:NP_001027220.1|refseq:NP_608658.1|ensemblmetazoa:FBgn0267378(gene)|ensemblmetazoa:FBtr0077840(transcript)|ensemblmetazoa:FBtr0100673(transcript)|ensemblmetazoa:FBtr0100674(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0007030"(Golgi organization)|go:"GO:0007053"(spindle assembly involved in male meiosis)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007110"(meiosis I cytokinesis)|go:"GO:0007111"(meiosis II cytokinesis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261 - - - figure legend:Figs. 1A, 2A|caution:Sequence of Q9VQ93 is one amino acid longer than the length of GOLPH3 given in the text.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/21 2014/10/16 - rogid:pl5ByOVOFAgSn6CXVoD8rkEP3wo7227 intact-crc:835BBB116EBDCEF3 false - necessary binding region:30-79|35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) chebi:"CHEBI:17526" uniprotkb:Q9H4A6 intact:EBI-2465282 intact:EBI-2465479|uniprotkb:Q9UIW5|ensembl:ENSP00000265070 psi-mi:pi4p(display_short)|psi-mi:"CHEBI:17526"(display_long) psi-mi:golp3_human(display_long)|uniprotkb:GOLPH3(gene name)|psi-mi:GOLPH3(display_short)|uniprotkb:GPP34(gene name synonym)|uniprotkb:Coat protein GPP34(gene name synonym)|uniprotkb:Mitochondrial DNA absence factor(gene name synonym) psi-mi:"MI:0049"(filter binding) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2465386|imex:IM-12096-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_071413.1|ensembl:ENSG00000113384(gene)|ensembl:ENST00000265070(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0009306"(protein secretion)|go:"GO:0010467"(gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261|mint:Q9H4A6|rcsb pdb:3KN1 - - - figure legend:Fig. 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/21 2014/10/16 - rogid:tHHREhHksCP+Yf9FzycM9cI+wkc9606 intact-crc:88908E45313726E7 false - 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) chebi:"CHEBI:16851" uniprotkb:Q9VSF0 intact:EBI-1257121 intact:EBI-2465447|uniprotkb:Q960R7|ensemblmetazoa:FBpp0076414|ensemblmetazoa:FBpp0076415|ensemblmetazoa:FBpp0076416|ensemblmetazoa:FBpp0312165 psi-mi:1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate(display_short)|psi-mi:"CHEBI:16851"(display_long) psi-mi:q9vsf0_drome(display_long)|uniprotkb:Atg18A(gene name synonym)|uniprotkb:atg18a(gene name synonym)|uniprotkb:CG7986(orf name)|uniprotkb:Dmel_CG7986(orf name)|uniprotkb:Atg18(gene name synonym)|uniprotkb:Atg18a(gene name)|psi-mi:Atg18a(display_short)|uniprotkb:atg18.1(gene name synonym)|uniprotkb:ATG18(gene name synonym)|uniprotkb:ATG18.1(gene name synonym)|uniprotkb:Dmel\CG7986(gene name synonym)|uniprotkb:atg18(gene name synonym) psi-mi:"MI:0049"(filter binding) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2465392|imex:IM-12096-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_648184.1|refseq:NP_729341.1|refseq:NP_996023.1|flybase:FBgn0035850|refseq:NP_001286977.1|ensemblmetazoa:FBgn0035850(gene)|ensemblmetazoa:FBtr0076691(transcript)|ensemblmetazoa:FBtr0076692(transcript)|ensemblmetazoa:FBtr0076693(transcript)|ensemblmetazoa:FBtr0346547(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006497"(protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035069"(larval midgut histolysis)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0051607"(defense response to virus)|go:"GO:0061723"(glycophagy)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032911|interpro:IPR036322 - - - figure legend:Fig. 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/21 2014/10/16 - rogid:3siT4ragFbV5I4qqO/6o3jfeyLA7227 intact-crc:8DA5513297B8E9F7 false - 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) chebi:"CHEBI:18348" uniprotkb:Q9VBD0 intact:EBI-1257123 intact:EBI-176791|ensemblmetazoa:FBpp0084408 psi-mi:1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate(display_short)|psi-mi:"CHEBI:18348"(display_long) psi-mi:q9vbd0_drome(display_long)|uniprotkb:Tb(gene name)|psi-mi:Tb(display_short)|uniprotkb:Dmel\CG5480(gene name synonym)|uniprotkb:Tu(gene name synonym)|uniprotkb:TwdlA(gene name synonym)|uniprotkb:Dmel_CG5480(orf name)|uniprotkb:CG5480(orf name) psi-mi:"MI:0049"(filter binding) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2465398|imex:IM-12096-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_651494.1|flybase:FBgn0243586|ensemblmetazoa:FBgn0243586(gene)|ensemblmetazoa:FBtr0085036(transcript)|go:"GO:0005214"(structural constituent of chitin-based cuticle)|go:"GO:0010171"(body morphogenesis)|go:"GO:0031012"(extracellular matrix)|go:"GO:0040003"(chitin-based cuticle development)|interpro:IPR004145(Protein of unknown function DUF243) - - - figure legend:Fig. 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/21 2014/10/16 - rogid:3czDMO3MOTp9dEN3ymCPXv+iKzA7227 intact-crc:A7A6FA4207E8B8E0 false - 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) chebi:"CHEBI:16152" uniprotkb:Q8INB9 intact:EBI-2296297 intact:EBI-162210|uniprotkb:Q0KI65|uniprotkb:Q24293|uniprotkb:Q24469|uniprotkb:Q24470|uniprotkb:Q7JN11|uniprotkb:Q8T9A5|uniprotkb:Q9VEY7|ensemblmetazoa:FBpp0082682 psi-mi:1-phosphatidyl-1d-myo-inositol 3,4-bisphosphate(display_short)|psi-mi:"CHEBI:16152"(display_long) psi-mi:akt1_drome(display_long)|uniprotkb:Akt1(gene name)|psi-mi:Akt1(display_short)|uniprotkb:CG4006(orf name)|uniprotkb:Akt(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym) psi-mi:"MI:0049"(filter binding) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2465404|imex:IM-12096-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_732113.3|refseq:NP_732114.1|refseq:NP_732115.1|flybase:FBgn0010379|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0090278"(negative regulation of peptide hormone secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR039026|reactome:R-DME-110478|reactome:R-DME-110523|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-1474151|reactome:R-DME-165158|reactome:R-DME-165159|reactome:R-DME-165181|reactome:R-DME-198323|reactome:R-DME-198693|reactome:R-DME-199418|reactome:R-DME-203615|reactome:R-DME-211163|reactome:R-DME-3769402|reactome:R-DME-389357|reactome:R-DME-389513|reactome:R-DME-392451|reactome:R-DME-450385|reactome:R-DME-450604|reactome:R-DME-5218920|reactome:R-DME-5628897|reactome:R-DME-6804759|reactome:R-DME-6811558|reactome:R-DME-69202|reactome:R-DME-69656|reactome:R-DME-8876198|reactome:R-DME-8948751|reactome:R-DME-9009391|reactome:R-DME-9604323|reactome:R-DME-9607240|reactome:R-DME-9614399|reactome:R-DME-9634638|ensemblmetazoa:FBgn0010379(gene)|ensemblmetazoa:FBtr0083228(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|refseq:NP_001287353.1|refseq:NP_001287354.1|dip:DIP-49060N - - - figure legend:Fig. 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/21 2014/10/16 - rogid:O+TwU/5zv00wpwqXLxtrJrHk3lw7227 intact-crc:4F1E4574CF672D24 false - 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) chebi:"CHEBI:16618" uniprotkb:Q8INB9 intact:EBI-1257125 intact:EBI-162210|uniprotkb:Q0KI65|uniprotkb:Q24293|uniprotkb:Q24469|uniprotkb:Q24470|uniprotkb:Q7JN11|uniprotkb:Q8T9A5|uniprotkb:Q9VEY7|ensemblmetazoa:FBpp0082682 psi-mi:1-phosphatidyl-1d-myo-inositol 3,4,5-trisphosphate(display_short)|psi-mi:"CHEBI:16618"(display_long) psi-mi:akt1_drome(display_long)|uniprotkb:Akt1(gene name)|psi-mi:Akt1(display_short)|uniprotkb:CG4006(orf name)|uniprotkb:Akt(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym) psi-mi:"MI:0049"(filter binding) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2465410|imex:IM-12096-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_732113.3|refseq:NP_732114.1|refseq:NP_732115.1|flybase:FBgn0010379|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0090278"(negative regulation of peptide hormone secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR039026|reactome:R-DME-110478|reactome:R-DME-110523|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-1474151|reactome:R-DME-165158|reactome:R-DME-165159|reactome:R-DME-165181|reactome:R-DME-198323|reactome:R-DME-198693|reactome:R-DME-199418|reactome:R-DME-203615|reactome:R-DME-211163|reactome:R-DME-3769402|reactome:R-DME-389357|reactome:R-DME-389513|reactome:R-DME-392451|reactome:R-DME-450385|reactome:R-DME-450604|reactome:R-DME-5218920|reactome:R-DME-5628897|reactome:R-DME-6804759|reactome:R-DME-6811558|reactome:R-DME-69202|reactome:R-DME-69656|reactome:R-DME-8876198|reactome:R-DME-8948751|reactome:R-DME-9009391|reactome:R-DME-9604323|reactome:R-DME-9607240|reactome:R-DME-9614399|reactome:R-DME-9634638|ensemblmetazoa:FBgn0010379(gene)|ensemblmetazoa:FBtr0083228(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|refseq:NP_001287353.1|refseq:NP_001287354.1|dip:DIP-49060N - - - figure legend:Fig. 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/21 2014/10/16 - rogid:O+TwU/5zv00wpwqXLxtrJrHk3lw7227 intact-crc:75BDDCEEF4563678 false - 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) chebi:"CHEBI:17526" uniprotkb:Q9Y128 intact:EBI-2465282 intact:EBI-158899|ensemblmetazoa:FBpp0076440|ensemblmetazoa:FBpp0311285 psi-mi:pi4p(display_short)|psi-mi:"CHEBI:17526"(display_long) psi-mi:q9y128_drome(display_long)|uniprotkb:Collagen type IV alpha-3-binding protein(gene name synonym)|uniprotkb:cert(gene name)|psi-mi:cert(display_short)|uniprotkb:BcDNA.GH07688(gene name synonym)|uniprotkb:"BcDNA:GH07688"(gene name synonym)|uniprotkb:CERT(gene name synonym)|uniprotkb:Dcert(gene name synonym)|uniprotkb:Dmel\CG7207(gene name synonym)|uniprotkb:dcert(gene name synonym)|uniprotkb:Dmel_CG7207(orf name)|uniprotkb:CG7207(orf name) psi-mi:"MI:0049"(filter binding) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2465416|imex:IM-12096-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensemblmetazoa:FBgn0027569(gene)|ensemblmetazoa:FBtr0076717(transcript)|ensemblmetazoa:FBtr0345035(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0035627"(ceramide transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0097001"(ceramide binding)|go:"GO:0120009"(intermembrane lipid transfer)|go:"GO:0120017"(ceramide transfer activity)|go:"GO:1902387"(ceramide 1-phosphate binding)|go:"GO:1902388"(ceramide 1-phosphate transfer activity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002913(Lipid-binding START)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023393|interpro:IPR041952|reactome:R-DME-1660661|refseq:NP_648199.1|flybase:FBgn0027569|refseq:NP_001286978.1 - - - figure legend:Fig. 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/21 2014/10/16 - rogid:dkCbxcdZS6RONctRCOiMfTsMLVY7227 intact-crc:F601F14E431FDE82 false - - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) chebi:"CHEBI:17283" uniprotkb:Q7K9H6 intact:EBI-1257113 intact:EBI-121909|intact:EBI-2465420|ensemblmetazoa:FBpp0071564 psi-mi:pi3p(display_short)|psi-mi:"CHEBI:17283"(display_long) psi-mi:q7k9h6_drome(display_long)|uniprotkb:Sara(gene name)|psi-mi:Sara(display_short)|uniprotkb:Sara-RA(gene name synonym)|uniprotkb:Dmel\CG15667(gene name synonym)|uniprotkb:SARA(gene name synonym)|uniprotkb:dSARA(gene name synonym)|uniprotkb:sara(gene name synonym)|uniprotkb:CG15667(orf name)|uniprotkb:Dmel_CG15667(orf name) psi-mi:"MI:0049"(filter binding) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2465438|imex:IM-12096-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensemblmetazoa:FBgn0026369(gene)|ensemblmetazoa:FBtr0071641(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016197"(endosomal transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048867"(stem cell fate determination)|go:"GO:0098722"(asymmetric stem cell division)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR024608|interpro:IPR035438|interpro:IPR037145|reactome:R-DME-201451|reactome:R-DME-2173789|refseq:NP_524729.2|flybase:FBgn0026369 - - - figure legend:Fig. 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/21 2014/10/16 - rogid:p6DtHG7PBLAtYvZRZ1N436it4x47227 intact-crc:8C0B0E1EB5B25490 false - 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) chebi:"CHEBI:17283" uniprotkb:Q9VSF0 intact:EBI-1257113 intact:EBI-2465447|uniprotkb:Q960R7|ensemblmetazoa:FBpp0076414|ensemblmetazoa:FBpp0076415|ensemblmetazoa:FBpp0076416|ensemblmetazoa:FBpp0312165 psi-mi:pi3p(display_short)|psi-mi:"CHEBI:17283"(display_long) psi-mi:q9vsf0_drome(display_long)|uniprotkb:Atg18A(gene name synonym)|uniprotkb:atg18a(gene name synonym)|uniprotkb:CG7986(orf name)|uniprotkb:Dmel_CG7986(orf name)|uniprotkb:Atg18(gene name synonym)|uniprotkb:Atg18a(gene name)|psi-mi:Atg18a(display_short)|uniprotkb:atg18.1(gene name synonym)|uniprotkb:ATG18(gene name synonym)|uniprotkb:ATG18.1(gene name synonym)|uniprotkb:Dmel\CG7986(gene name synonym)|uniprotkb:atg18(gene name synonym) psi-mi:"MI:0049"(filter binding) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2465466|imex:IM-12096-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_648184.1|refseq:NP_729341.1|refseq:NP_996023.1|flybase:FBgn0035850|refseq:NP_001286977.1|ensemblmetazoa:FBgn0035850(gene)|ensemblmetazoa:FBtr0076691(transcript)|ensemblmetazoa:FBtr0076692(transcript)|ensemblmetazoa:FBtr0076693(transcript)|ensemblmetazoa:FBtr0346547(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006497"(protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035069"(larval midgut histolysis)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0051607"(defense response to virus)|go:"GO:0061723"(glycophagy)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032911|interpro:IPR036322 - - - figure legend:Fig. 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/21 2014/10/16 - rogid:3siT4ragFbV5I4qqO/6o3jfeyLA7227 intact-crc:051B9CF4AB3FA500 false - 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) chebi:"CHEBI:17526" uniprotkb:Q9VQ93 intact:EBI-2465282 intact:EBI-84891|ensemblmetazoa:FBpp0100138|ensemblmetazoa:FBpp0100140|ensemblmetazoa:FBpp0100141 psi-mi:pi4p(display_short)|psi-mi:"CHEBI:17526"(display_long) psi-mi:golp3_drome(display_long)|uniprotkb:sau(gene name)|psi-mi:sau(display_short)|uniprotkb:GOLPH3(gene name synonym)|uniprotkb:Protein rotini(gene name synonym)|uniprotkb:"l(2)s5379"(gene name synonym)|uniprotkb:rti(gene name synonym)|uniprotkb:CG7085(orf name) psi-mi:"MI:0049"(filter binding) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2465625|imex:IM-12096-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - flybase:FBgn0267378|refseq:NP_001014460.1|refseq:NP_001027220.1|refseq:NP_608658.1|ensemblmetazoa:FBgn0267378(gene)|ensemblmetazoa:FBtr0077840(transcript)|ensemblmetazoa:FBtr0100673(transcript)|ensemblmetazoa:FBtr0100674(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0007030"(Golgi organization)|go:"GO:0007053"(spindle assembly involved in male meiosis)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007110"(meiosis I cytokinesis)|go:"GO:0007111"(meiosis II cytokinesis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261 - - - figure legend:Supp. Fig. 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/21 2014/10/16 - rogid:pl5ByOVOFAgSn6CXVoD8rkEP3wo7227 intact-crc:BC9F008372737A35 false - glutathione s tranferase tag:?-?|35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) chebi:"CHEBI:17526" uniprotkb:Q9H4A6 intact:EBI-2465282 intact:EBI-2465479|uniprotkb:Q9UIW5|ensembl:ENSP00000265070 psi-mi:pi4p(display_short)|psi-mi:"CHEBI:17526"(display_long) psi-mi:golp3_human(display_long)|uniprotkb:GOLPH3(gene name)|psi-mi:GOLPH3(display_short)|uniprotkb:GPP34(gene name synonym)|uniprotkb:Coat protein GPP34(gene name synonym)|uniprotkb:Mitochondrial DNA absence factor(gene name synonym) psi-mi:"MI:0049"(filter binding) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2465634|imex:IM-12096-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_071413.1|ensembl:ENSG00000113384(gene)|ensembl:ENST00000265070(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0009306"(protein secretion)|go:"GO:0010467"(gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261|mint:Q9H4A6|rcsb pdb:3KN1 - - - figure legend:Supp. Fig. 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/21 2014/10/16 - rogid:tHHREhHksCP+Yf9FzycM9cI+wkc9606 intact-crc:8BEA0003E5180F68 false - 35s radiolabel:?-?|glutathione s tranferase tag:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) chebi:"CHEBI:17526" uniprotkb:Q9H4A6 intact:EBI-2465282 intact:EBI-2465479|uniprotkb:Q9UIW5|ensembl:ENSP00000265070 psi-mi:pi4p(display_short)|psi-mi:"CHEBI:17526"(display_long) psi-mi:golp3_human(display_long)|uniprotkb:GOLPH3(gene name)|psi-mi:GOLPH3(display_short)|uniprotkb:GPP34(gene name synonym)|uniprotkb:Coat protein GPP34(gene name synonym)|uniprotkb:Mitochondrial DNA absence factor(gene name synonym) psi-mi:"MI:1211"(liposome binding assay) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2465515|imex:IM-12096-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_071413.1|ensembl:ENSG00000113384(gene)|ensembl:ENST00000265070(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0009306"(protein secretion)|go:"GO:0010467"(gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261|mint:Q9H4A6|rcsb pdb:3KN1 - - - figure legend:Figs. 2D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/21 2014/10/16 - rogid:tHHREhHksCP+Yf9FzycM9cI+wkc9606 intact-crc:2DF4245057A1E4EE false - mutation decreasing interaction:174-174,171-171|mutation decreasing interaction:90-90 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9H4A6 uniprotkb:Q92614 intact:EBI-2465479|uniprotkb:Q9UIW5|ensembl:ENSP00000265070 intact:EBI-949059|ensembl:ENSP00000437073|uniprotkb:Q5H9U3|uniprotkb:Q5W9F9|uniprotkb:Q5W9G1|uniprotkb:Q8IXP8|uniprotkb:Q5QD01 psi-mi:golp3_human(display_long)|uniprotkb:GOLPH3(gene name)|psi-mi:GOLPH3(display_short)|uniprotkb:GPP34(gene name synonym)|uniprotkb:Coat protein GPP34(gene name synonym)|uniprotkb:Mitochondrial DNA absence factor(gene name synonym) psi-mi:my18a_human(display_long)|uniprotkb:Myosin containing a PDZ domain(gene name synonym)|uniprotkb:Molecule associated with JAK3 N-terminus(gene name synonym)|uniprotkb:MYO18A(gene name)|psi-mi:MYO18A(display_short)|uniprotkb:KIAA0216(gene name synonym)|uniprotkb:MYSPDZ(gene name synonym)|uniprotkb:CD245(gene name synonym)|uniprotkb:Surfactant protein receptor SP-R210(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2465554|imex:IM-12096-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_071413.1|ensembl:ENSG00000113384(gene)|ensembl:ENST00000265070(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0009306"(protein secretion)|go:"GO:0010467"(gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261|mint:Q9H4A6|rcsb pdb:3KN1 dip:DIP-46631N|ensembl:ENSG00000196535(gene)|ensembl:ENST00000527372(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016477"(cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042641"(actomyosin)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043531"(ADP binding)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|go:"GO:1903028"(positive regulation of opsonization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR020587|interpro:IPR027417|interpro:IPR031244|interpro:IPR036034|interpro:IPR036064|interpro:IPR036961|interpro:IPR041489|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|refseq:NP_510880.2|refseq:NP_976063.1|refseq:NP_001333696.1|refseq:NP_001333697.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 4C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/10/21 2014/10/16 rogid:tHHREhHksCP+Yf9FzycM9cI+wkc9606 rogid:IunEYt79RO62wU6VU2gv16Xb7Lk9606 intact-crc:990661BCD17B0017|rigid:H8qyekgeJm8dXYarnknCExMxybw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92614 uniprotkb:Q9H4A6 intact:EBI-949059|ensembl:ENSP00000437073|uniprotkb:Q5H9U3|uniprotkb:Q5W9F9|uniprotkb:Q5W9G1|uniprotkb:Q8IXP8|uniprotkb:Q5QD01 intact:EBI-2465479|uniprotkb:Q9UIW5|ensembl:ENSP00000265070 psi-mi:my18a_human(display_long)|uniprotkb:Myosin containing a PDZ domain(gene name synonym)|uniprotkb:Molecule associated with JAK3 N-terminus(gene name synonym)|uniprotkb:MYO18A(gene name)|psi-mi:MYO18A(display_short)|uniprotkb:KIAA0216(gene name synonym)|uniprotkb:MYSPDZ(gene name synonym)|uniprotkb:CD245(gene name synonym)|uniprotkb:Surfactant protein receptor SP-R210(gene name synonym) psi-mi:golp3_human(display_long)|uniprotkb:GOLPH3(gene name)|psi-mi:GOLPH3(display_short)|uniprotkb:GPP34(gene name synonym)|uniprotkb:Coat protein GPP34(gene name synonym)|uniprotkb:Mitochondrial DNA absence factor(gene name synonym) psi-mi:"MI:0096"(pull down) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2465598|imex:IM-12096-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-46631N|ensembl:ENSG00000196535(gene)|ensembl:ENST00000527372(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016477"(cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042641"(actomyosin)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043531"(ADP binding)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|go:"GO:1903028"(positive regulation of opsonization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR020587|interpro:IPR027417|interpro:IPR031244|interpro:IPR036034|interpro:IPR036064|interpro:IPR036961|interpro:IPR041489|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|refseq:NP_510880.2|refseq:NP_976063.1|refseq:NP_001333696.1|refseq:NP_001333697.1 refseq:NP_071413.1|ensembl:ENSG00000113384(gene)|ensembl:ENST00000265070(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0009306"(protein secretion)|go:"GO:0010467"(gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261|mint:Q9H4A6|rcsb pdb:3KN1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 4E|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/21 2014/10/16 rogid:IunEYt79RO62wU6VU2gv16Xb7Lk9606 rogid:tHHREhHksCP+Yf9FzycM9cI+wkc9606 intact-crc:6D03BFF8537C0BFC|rigid:H8qyekgeJm8dXYarnknCExMxybw false his tag:?-?|tag:?-?|sufficient binding region:1-406|sufficient binding region:408-1242 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9H4A6 uniprotkb:Q92614 intact:EBI-2465479|uniprotkb:Q9UIW5|ensembl:ENSP00000265070 intact:EBI-949059|ensembl:ENSP00000437073|uniprotkb:Q5H9U3|uniprotkb:Q5W9F9|uniprotkb:Q5W9G1|uniprotkb:Q8IXP8|uniprotkb:Q5QD01 psi-mi:golp3_human(display_long)|uniprotkb:GOLPH3(gene name)|psi-mi:GOLPH3(display_short)|uniprotkb:GPP34(gene name synonym)|uniprotkb:Coat protein GPP34(gene name synonym)|uniprotkb:Mitochondrial DNA absence factor(gene name synonym) psi-mi:my18a_human(display_long)|uniprotkb:Myosin containing a PDZ domain(gene name synonym)|uniprotkb:Molecule associated with JAK3 N-terminus(gene name synonym)|uniprotkb:MYO18A(gene name)|psi-mi:MYO18A(display_short)|uniprotkb:KIAA0216(gene name synonym)|uniprotkb:MYSPDZ(gene name synonym)|uniprotkb:CD245(gene name synonym)|uniprotkb:Surfactant protein receptor SP-R210(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2465618|imex:IM-12096-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_071413.1|ensembl:ENSG00000113384(gene)|ensembl:ENST00000265070(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0009306"(protein secretion)|go:"GO:0010467"(gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261|mint:Q9H4A6|rcsb pdb:3KN1 dip:DIP-46631N|ensembl:ENSG00000196535(gene)|ensembl:ENST00000527372(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016477"(cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042641"(actomyosin)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043531"(ADP binding)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|go:"GO:1903028"(positive regulation of opsonization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR020587|interpro:IPR027417|interpro:IPR031244|interpro:IPR036034|interpro:IPR036064|interpro:IPR036961|interpro:IPR041489|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|refseq:NP_510880.2|refseq:NP_976063.1|refseq:NP_001333696.1|refseq:NP_001333697.1 go:"GO:0005794"(Golgi apparatus) - - figure legend:Fig. 4F|comment:The Golgi protein GOLGA4 was searately shown to localise in the same region. Knockdown of GOLPH3 causes loss of MYO18A from Golgi|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/10/21 2014/10/16 rogid:tHHREhHksCP+Yf9FzycM9cI+wkc9606 rogid:IunEYt79RO62wU6VU2gv16Xb7Lk9606 intact-crc:6FC998D7CCC6FE02|rigid:H8qyekgeJm8dXYarnknCExMxybw false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9H4A6 uniprotkb:Q92614 intact:EBI-2465479|uniprotkb:Q9UIW5|ensembl:ENSP00000265070 intact:EBI-949059|ensembl:ENSP00000437073|uniprotkb:Q5H9U3|uniprotkb:Q5W9F9|uniprotkb:Q5W9G1|uniprotkb:Q8IXP8|uniprotkb:Q5QD01 psi-mi:golp3_human(display_long)|uniprotkb:GOLPH3(gene name)|psi-mi:GOLPH3(display_short)|uniprotkb:GPP34(gene name synonym)|uniprotkb:Coat protein GPP34(gene name synonym)|uniprotkb:Mitochondrial DNA absence factor(gene name synonym) psi-mi:my18a_human(display_long)|uniprotkb:Myosin containing a PDZ domain(gene name synonym)|uniprotkb:Molecule associated with JAK3 N-terminus(gene name synonym)|uniprotkb:MYO18A(gene name)|psi-mi:MYO18A(display_short)|uniprotkb:KIAA0216(gene name synonym)|uniprotkb:MYSPDZ(gene name synonym)|uniprotkb:CD245(gene name synonym)|uniprotkb:Surfactant protein receptor SP-R210(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Dippold et al. (2009) imex:IM-12096|pubmed:19837035 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2465650|imex:IM-12096-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_071413.1|ensembl:ENSG00000113384(gene)|ensembl:ENST00000265070(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0009306"(protein secretion)|go:"GO:0010467"(gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261|mint:Q9H4A6|rcsb pdb:3KN1 dip:DIP-46631N|ensembl:ENSG00000196535(gene)|ensembl:ENST00000527372(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016477"(cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042641"(actomyosin)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043531"(ADP binding)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|go:"GO:1903028"(positive regulation of opsonization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR020587|interpro:IPR027417|interpro:IPR031244|interpro:IPR036034|interpro:IPR036064|interpro:IPR036961|interpro:IPR041489|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|refseq:NP_510880.2|refseq:NP_976063.1|refseq:NP_001333696.1|refseq:NP_001333697.1 psi-mi:"MI:0469"(intact) - - figure legend:Supp. Fig. 12|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/10/21 2014/10/16 rogid:tHHREhHksCP+Yf9FzycM9cI+wkc9606 rogid:IunEYt79RO62wU6VU2gv16Xb7Lk9606 intact-crc:23590C4613888469|rigid:H8qyekgeJm8dXYarnknCExMxybw false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)