#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O43070 uniprotkb:O74986 intact:EBI-2125045|uniprotkb:Q86ZQ0|ensemblfungi:"SPBC6B1.09c.1:pep" intact:EBI-2463766|uniprotkb:A9LJ21|ensemblfungi:"SPCC338.08.1:pep" psi-mi:nbs1_schpo(display_long)|uniprotkb:nbs1(gene name)|psi-mi:nbs1(display_short)|uniprotkb:SPBC6B1.09c(orf name) psi-mi:com1_schpo(display_long)|uniprotkb:Double-strand break repair protein ctp1(gene name synonym)|uniprotkb:Sporulation in the absence of SPO11 protein 2 homolog(gene name synonym)|uniprotkb:ctp1(gene name)|psi-mi:ctp1(display_short)|uniprotkb:mug38(gene name synonym)|uniprotkb:nip1(gene name synonym)|uniprotkb:slr9(gene name synonym)|uniprotkb:Nbs1-interacting protein 1(gene name synonym)|uniprotkb:Meiotically up-regulated gene 38 protein(gene name synonym)|uniprotkb:SPCC338.08(orf name) psi-mi:"MI:0676"(tandem affinity purification) Williams et al. (2009) imex:IM-12089|pubmed:19804755 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2463784|imex:IM-12089-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018823.1|dip:DIP-52387N|reactome:R-SPO-2559586|reactome:R-SPO-5685939|reactome:R-SPO-5693548|reactome:R-SPO-5693565|ensemblfungi:SPBC6B1.09c(gene)|ensemblfungi:SPBC6B1.09c.1(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1990166"(protein localization to site of double-strand break)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR036420|interpro:IPR040227|rcsb pdb:3HUE|rcsb pdb:3HUF|rcsb pdb:3I0M|rcsb pdb:3I0N|rcsb pdb:4FBK|rcsb pdb:4FBQ|rcsb pdb:4FBW refseq:NP_588159.2|dip:DIP-54853N|ensemblfungi:SPCC338.08(gene)|ensemblfungi:SPCC338.08.1(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0070336"(flap-structured DNA binding)|go:"GO:0106260"(DNA-DNA tethering activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|go:"GO:0120290"(stalled replication fork localization to nuclear periphery)|go:"GO:1903211"(mitotic recombination involved in replication fork processing)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|go:"GO:1990899"(meiotic DNA double-strand break resectioning)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR033316|rcsb pdb:3HUF|rcsb pdb:4X01 psi-mi:"MI:0469"(intact) crc64:B3384CCC85F96DD1 crc64:857AD70D23B88D68 figure legend:Fig. 3G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2009/10/15 2014/10/16 rogid:5h/qx0stPyVRQ9vtqO50Ftq0mvM284812 rogid:fr8PErR9V8pkC9g84uSjFyW5BDg284812 intact-crc:AF7FB358931A403A|rigid:VMF/FEVrRdvT4lNbmzvl8XYZOQU false mutation decreasing interaction:45-45,27-27|flag tag:?-? calmodulin binding peptide plus protein a tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O74986 uniprotkb:O43070 intact:EBI-2463766|uniprotkb:A9LJ21|ensemblfungi:"SPCC338.08.1:pep" intact:EBI-2125045|uniprotkb:Q86ZQ0|ensemblfungi:"SPBC6B1.09c.1:pep" psi-mi:com1_schpo(display_long)|uniprotkb:Double-strand break repair protein ctp1(gene name synonym)|uniprotkb:Sporulation in the absence of SPO11 protein 2 homolog(gene name synonym)|uniprotkb:ctp1(gene name)|psi-mi:ctp1(display_short)|uniprotkb:mug38(gene name synonym)|uniprotkb:nip1(gene name synonym)|uniprotkb:slr9(gene name synonym)|uniprotkb:Nbs1-interacting protein 1(gene name synonym)|uniprotkb:Meiotically up-regulated gene 38 protein(gene name synonym)|uniprotkb:SPCC338.08(orf name) psi-mi:nbs1_schpo(display_long)|uniprotkb:nbs1(gene name)|psi-mi:nbs1(display_short)|uniprotkb:SPBC6B1.09c(orf name) psi-mi:"MI:0071"(molecular sieving) Williams et al. (2009) imex:IM-12089|pubmed:19804755 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2463850|imex:IM-12089-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_588159.2|dip:DIP-54853N|ensemblfungi:SPCC338.08(gene)|ensemblfungi:SPCC338.08.1(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0070336"(flap-structured DNA binding)|go:"GO:0106260"(DNA-DNA tethering activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|go:"GO:0120290"(stalled replication fork localization to nuclear periphery)|go:"GO:1903211"(mitotic recombination involved in replication fork processing)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|go:"GO:1990899"(meiotic DNA double-strand break resectioning)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR033316|rcsb pdb:3HUF|rcsb pdb:4X01 refseq:NP_001018823.1|dip:DIP-52387N|reactome:R-SPO-2559586|reactome:R-SPO-5685939|reactome:R-SPO-5693548|reactome:R-SPO-5693565|ensemblfungi:SPBC6B1.09c(gene)|ensemblfungi:SPBC6B1.09c.1(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1990166"(protein localization to site of double-strand break)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR036420|interpro:IPR040227|rcsb pdb:3HUE|rcsb pdb:3HUF|rcsb pdb:3I0M|rcsb pdb:3I0N|rcsb pdb:4FBK|rcsb pdb:4FBQ|rcsb pdb:4FBW psi-mi:"MI:0469"(intact) crc64:857AD70D23B88D68 crc64:B3384CCC85F96DD1 figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/15 2014/10/16 rogid:fr8PErR9V8pkC9g84uSjFyW5BDg284812 rogid:5h/qx0stPyVRQ9vtqO50Ftq0mvM284812 intact-crc:03855841684E462A|rigid:VMF/FEVrRdvT4lNbmzvl8XYZOQU false phosphorylated residue:79-79,77-77|sufficient binding region:72-83|fluorescent dye label:?-?|sufficient binding region:82-94|phosphorylated residue:87-87,89-89 sufficient binding region:1-329|mutation decreasing interaction:45-45,27-27|his tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43070 uniprotkb:O74986 intact:EBI-2125045|uniprotkb:Q86ZQ0|ensemblfungi:"SPBC6B1.09c.1:pep" intact:EBI-2463766|uniprotkb:A9LJ21|ensemblfungi:"SPCC338.08.1:pep" psi-mi:nbs1_schpo(display_long)|uniprotkb:nbs1(gene name)|psi-mi:nbs1(display_short)|uniprotkb:SPBC6B1.09c(orf name) psi-mi:com1_schpo(display_long)|uniprotkb:Double-strand break repair protein ctp1(gene name synonym)|uniprotkb:Sporulation in the absence of SPO11 protein 2 homolog(gene name synonym)|uniprotkb:ctp1(gene name)|psi-mi:ctp1(display_short)|uniprotkb:mug38(gene name synonym)|uniprotkb:nip1(gene name synonym)|uniprotkb:slr9(gene name synonym)|uniprotkb:Nbs1-interacting protein 1(gene name synonym)|uniprotkb:Meiotically up-regulated gene 38 protein(gene name synonym)|uniprotkb:SPCC338.08(orf name) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Williams et al. (2009) imex:IM-12089|pubmed:19804755 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2463880|imex:IM-12089-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018823.1|dip:DIP-52387N|reactome:R-SPO-2559586|reactome:R-SPO-5685939|reactome:R-SPO-5693548|reactome:R-SPO-5693565|ensemblfungi:SPBC6B1.09c(gene)|ensemblfungi:SPBC6B1.09c.1(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1990166"(protein localization to site of double-strand break)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR036420|interpro:IPR040227|rcsb pdb:3HUE|rcsb pdb:3HUF|rcsb pdb:3I0M|rcsb pdb:3I0N|rcsb pdb:4FBK|rcsb pdb:4FBQ|rcsb pdb:4FBW refseq:NP_588159.2|dip:DIP-54853N|ensemblfungi:SPCC338.08(gene)|ensemblfungi:SPCC338.08.1(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0070336"(flap-structured DNA binding)|go:"GO:0106260"(DNA-DNA tethering activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|go:"GO:0120290"(stalled replication fork localization to nuclear periphery)|go:"GO:1903211"(mitotic recombination involved in replication fork processing)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|go:"GO:1990899"(meiotic DNA double-strand break resectioning)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR033316|rcsb pdb:3HUF|rcsb pdb:4X01 psi-mi:"MI:0469"(intact) crc64:B3384CCC85F96DD1 crc64:857AD70D23B88D68 figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/15 2014/10/16 rogid:5h/qx0stPyVRQ9vtqO50Ftq0mvM284812 rogid:fr8PErR9V8pkC9g84uSjFyW5BDg284812 intact-crc:4ABBD259CD2A84AC|rigid:VMF/FEVrRdvT4lNbmzvl8XYZOQU false sufficient binding region:1-329|mutation decreasing interaction:45-45,27-27|his tag:c-c O-phospho-L-threonine:79-79|sufficient binding region:72-83|fluorescent dye label:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O74986 uniprotkb:O43070 intact:EBI-2463766|uniprotkb:A9LJ21|ensemblfungi:"SPCC338.08.1:pep" intact:EBI-2125045|uniprotkb:Q86ZQ0|ensemblfungi:"SPBC6B1.09c.1:pep" psi-mi:com1_schpo(display_long)|uniprotkb:Double-strand break repair protein ctp1(gene name synonym)|uniprotkb:Sporulation in the absence of SPO11 protein 2 homolog(gene name synonym)|uniprotkb:ctp1(gene name)|psi-mi:ctp1(display_short)|uniprotkb:mug38(gene name synonym)|uniprotkb:nip1(gene name synonym)|uniprotkb:slr9(gene name synonym)|uniprotkb:Nbs1-interacting protein 1(gene name synonym)|uniprotkb:Meiotically up-regulated gene 38 protein(gene name synonym)|uniprotkb:SPCC338.08(orf name) psi-mi:nbs1_schpo(display_long)|uniprotkb:nbs1(gene name)|psi-mi:nbs1(display_short)|uniprotkb:SPBC6B1.09c(orf name) psi-mi:"MI:0114"(x-ray crystallography) Williams et al. (2009) imex:IM-12089|pubmed:19804755 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2463905|wwpdb:3huf|imex:IM-12089-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_588159.2|dip:DIP-54853N|ensemblfungi:SPCC338.08(gene)|ensemblfungi:SPCC338.08.1(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0070336"(flap-structured DNA binding)|go:"GO:0106260"(DNA-DNA tethering activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|go:"GO:0120290"(stalled replication fork localization to nuclear periphery)|go:"GO:1903211"(mitotic recombination involved in replication fork processing)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|go:"GO:1990899"(meiotic DNA double-strand break resectioning)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR033316|rcsb pdb:3HUF|rcsb pdb:4X01 refseq:NP_001018823.1|dip:DIP-52387N|reactome:R-SPO-2559586|reactome:R-SPO-5685939|reactome:R-SPO-5693548|reactome:R-SPO-5693565|ensemblfungi:SPBC6B1.09c(gene)|ensemblfungi:SPBC6B1.09c.1(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1990166"(protein localization to site of double-strand break)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR036420|interpro:IPR040227|rcsb pdb:3HUE|rcsb pdb:3HUF|rcsb pdb:3I0M|rcsb pdb:3I0N|rcsb pdb:4FBK|rcsb pdb:4FBQ|rcsb pdb:4FBW - crc64:857AD70D23B88D68 crc64:B3384CCC85F96DD1 figure legend:Supp. Table 2, Fig. 6 and Supp. Fig. 8|3d-resolution:2.15 A|3d-r-factors:"R-factor: 21.8%, Free R-factor: 26.2%"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/10/15 2014/10/16 rogid:fr8PErR9V8pkC9g84uSjFyW5BDg284812 rogid:5h/qx0stPyVRQ9vtqO50Ftq0mvM284812 intact-crc:022898AE79EB299F|rigid:VMF/FEVrRdvT4lNbmzvl8XYZOQU false sufficient binding region:72-83|fluorescent dye label:?-? sufficient binding region:1-321|his tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)