#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9WYT9	uniprotkb:Q9WZV7	intact:EBI-2464826|uniprotkb:G4FE02|ensemblbacteria:AAD35552	intact:EBI-2464828|uniprotkb:G4FCX1|ensemblbacteria:AAD35935	psi-mi:q9wyt9_thema(display_long)|uniprotkb:TM_0468(locus name)	psi-mi:q9wzv7_thema(display_long)|uniprotkb:TM_0853(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Casino et al. (2009)	imex:IM-12095|pubmed:19800110	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2464830|wwpdb:3dge|imex:IM-12095-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_228278.1|refseq:WP_004081498.1|dip:DIP-54543N|ensemblbacteria:AAD35552(transcript)|ensemblbacteria:TM_0468(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0046872"(metal ion binding)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|rcsb pdb:3DGE|rcsb pdb:3DGF|rcsb pdb:3GL9|rcsb pdb:4JA2|rcsb pdb:4JAS|rcsb pdb:4JAV|rcsb pdb:5UHT|rcsb pdb:6AZR|rcsb pdb:6RFV|rcsb pdb:6RGY|rcsb pdb:6RGZ|rcsb pdb:6RH0|rcsb pdb:6RH1|rcsb pdb:6RH7|rcsb pdb:6RH8|rcsb pdb:6RH2	refseq:NP_228662.1|refseq:WP_004080773.1|dip:DIP-54544N|ensemblbacteria:AAD35935(transcript)|ensemblbacteria:TM_0853(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:2C2A|rcsb pdb:3DGE|rcsb pdb:4JAS|rcsb pdb:4JAU|rcsb pdb:4JAV|rcsb pdb:4KP4|rcsb pdb:5UHT|rcsb pdb:6AZR|rcsb pdb:6RFV|rcsb pdb:6RGY|rcsb pdb:6RGZ|rcsb pdb:6RH0|rcsb pdb:6RH1|rcsb pdb:6RH2|rcsb pdb:6RH7|rcsb pdb:6RH8	-	-	-	3d-r-factors:"R-factor: 23.6%, Free R-factor: 28.4%"|3d-resolution:2.8A|figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/10/21	2014/10/16	rogid:CP5OYhveeLzc1oa71/pfzAOfw9w243274	rogid:j+CHLIKfJUS5ZjDDg8REwHnTJDY243274	intact-crc:216845A0FA1DC37A|rigid:+/Jt8vvXHDBBGmkjcxxp1kyMSDI	false	-	sufficient binding region:232-489(IPR005467)	2	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9WYT9	uniprotkb:Q9WZV7	intact:EBI-2464826|uniprotkb:G4FE02|ensemblbacteria:AAD35552	intact:EBI-2464828|uniprotkb:G4FCX1|ensemblbacteria:AAD35935	psi-mi:q9wyt9_thema(display_long)|uniprotkb:TM_0468(locus name)	psi-mi:q9wzv7_thema(display_long)|uniprotkb:TM_0853(locus name)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Casino et al. (2009)	imex:IM-12095|pubmed:19800110	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2464847|wwpdb:3dge|imex:IM-12095-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_228278.1|refseq:WP_004081498.1|dip:DIP-54543N|ensemblbacteria:AAD35552(transcript)|ensemblbacteria:TM_0468(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0046872"(metal ion binding)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|rcsb pdb:3DGE|rcsb pdb:3DGF|rcsb pdb:3GL9|rcsb pdb:4JA2|rcsb pdb:4JAS|rcsb pdb:4JAV|rcsb pdb:5UHT|rcsb pdb:6AZR|rcsb pdb:6RFV|rcsb pdb:6RGY|rcsb pdb:6RGZ|rcsb pdb:6RH0|rcsb pdb:6RH1|rcsb pdb:6RH7|rcsb pdb:6RH8|rcsb pdb:6RH2	refseq:NP_228662.1|refseq:WP_004080773.1|dip:DIP-54544N|ensemblbacteria:AAD35935(transcript)|ensemblbacteria:TM_0853(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:2C2A|rcsb pdb:3DGE|rcsb pdb:4JAS|rcsb pdb:4JAU|rcsb pdb:4JAV|rcsb pdb:4KP4|rcsb pdb:5UHT|rcsb pdb:6AZR|rcsb pdb:6RFV|rcsb pdb:6RGY|rcsb pdb:6RGZ|rcsb pdb:6RH0|rcsb pdb:6RH1|rcsb pdb:6RH2|rcsb pdb:6RH7|rcsb pdb:6RH8	-	-	-	3d-r-factors:"R-factor: 23.6%, Free R-factor: 28.4%"|3d-resolution:2.8A|figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/10/21	2014/10/16	rogid:CP5OYhveeLzc1oa71/pfzAOfw9w243274	rogid:j+CHLIKfJUS5ZjDDg8REwHnTJDY243274	intact-crc:9ECE49EA001A9BD6|rigid:+/Jt8vvXHDBBGmkjcxxp1kyMSDI	false	mutation disrupting interaction:17-17|mutation disrupting interaction:20-20	sufficient binding region:232-489(IPR005467)|mutation disrupting interaction:272-272|mutation decreasing interaction:267-267	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9WZV7	-	intact:EBI-2464828|uniprotkb:G4FCX1|ensemblbacteria:AAD35935	-	psi-mi:q9wzv7_thema(display_long)|uniprotkb:TM_0853(locus name)	-	psi-mi:"MI:0424"(protein kinase assay)	Casino et al. (2009)	imex:IM-12095|pubmed:19800110	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	-	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2464932|imex:IM-12095-3	-	-	psi-mi:"MI:0503"(self)	-	psi-mi:"MI:0503"(self)	-	psi-mi:"MI:0326"(protein)	-	refseq:NP_228662.1|refseq:WP_004080773.1|dip:DIP-54544N|ensemblbacteria:AAD35935(transcript)|ensemblbacteria:TM_0853(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:2C2A|rcsb pdb:3DGE|rcsb pdb:4JAS|rcsb pdb:4JAU|rcsb pdb:4JAV|rcsb pdb:4KP4|rcsb pdb:5UHT|rcsb pdb:6AZR|rcsb pdb:6RFV|rcsb pdb:6RGY|rcsb pdb:6RGZ|rcsb pdb:6RH0|rcsb pdb:6RH1|rcsb pdb:6RH2|rcsb pdb:6RH7|rcsb pdb:6RH8	-	go:"GO:0004672"(protein kinase activity)|go:"GO:0046777"(protein autophosphorylation)	-	-	figure legend:Fig. 3C, 5A-E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/10/21	2014/10/16	rogid:j+CHLIKfJUS5ZjDDg8REwHnTJDY243274	-	intact-crc:03347A178FAB2596	false	sufficient binding region:232-489|his tag:c-c	-	1	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	-
uniprotkb:Q9WZV7	uniprotkb:Q9WZV7	intact:EBI-2464828|uniprotkb:G4FCX1|ensemblbacteria:AAD35935	intact:EBI-2464828|uniprotkb:G4FCX1|ensemblbacteria:AAD35935	psi-mi:q9wzv7_thema(display_long)|uniprotkb:TM_0853(locus name)	psi-mi:q9wzv7_thema(display_long)|uniprotkb:TM_0853(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Casino et al. (2009)	imex:IM-12095|pubmed:19800110	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2465022|imex:IM-12095-2	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_228662.1|refseq:WP_004080773.1|dip:DIP-54544N|ensemblbacteria:AAD35935(transcript)|ensemblbacteria:TM_0853(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:2C2A|rcsb pdb:3DGE|rcsb pdb:4JAS|rcsb pdb:4JAU|rcsb pdb:4JAV|rcsb pdb:4KP4|rcsb pdb:5UHT|rcsb pdb:6AZR|rcsb pdb:6RFV|rcsb pdb:6RGY|rcsb pdb:6RGZ|rcsb pdb:6RH0|rcsb pdb:6RH1|rcsb pdb:6RH2|rcsb pdb:6RH7|rcsb pdb:6RH8	refseq:NP_228662.1|refseq:WP_004080773.1|dip:DIP-54544N|ensemblbacteria:AAD35935(transcript)|ensemblbacteria:TM_0853(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:2C2A|rcsb pdb:3DGE|rcsb pdb:4JAS|rcsb pdb:4JAU|rcsb pdb:4JAV|rcsb pdb:4KP4|rcsb pdb:5UHT|rcsb pdb:6AZR|rcsb pdb:6RFV|rcsb pdb:6RGY|rcsb pdb:6RGZ|rcsb pdb:6RH0|rcsb pdb:6RH1|rcsb pdb:6RH2|rcsb pdb:6RH7|rcsb pdb:6RH8	go:"GO:0046777"(protein autophosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/10/21	2014/10/16	rogid:j+CHLIKfJUS5ZjDDg8REwHnTJDY243274	rogid:j+CHLIKfJUS5ZjDDg8REwHnTJDY243274	intact-crc:AC34D3843F0384A3|rigid:tu3BmkC76Dr6vELU7ishYPJppts	false	mutation:260-260|his tag:c-c	sufficient binding region:232-489|his tag:c-c|mutation:260-260	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:A0A0H3K900	-	intact:EBI-2465150|ensemblbacteria:BAF67857	-	psi-mi:a0a0h3k900_staae(display_long)|uniprotkb:phoR(gene name)|psi-mi:phoR(display_short)|uniprotkb:NWMN_1585(locus name)	-	psi-mi:"MI:0424"(protein kinase assay)	Casino et al. (2009)	imex:IM-12095|pubmed:19800110	taxid:426430(staae)|taxid:426430("Staphylococcus aureus (strain Newman)")	-	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2465076|imex:IM-12095-4	-	-	psi-mi:"MI:0503"(self)	-	psi-mi:"MI:0503"(self)	-	psi-mi:"MI:0326"(protein)	-	uniprotkb:A6QHM5(uniprot-removed-ac)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890|ensemblbacteria:BAF67857(transcript)|ensemblbacteria:NWMN_1585(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)	-	go:"GO:0046777"(protein autophosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:Fig. 5F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/10/21	2014/10/16	rogid:f1Y/+UDZ3WsP2yvsjJf94FntkZw426430	-	intact-crc:7BBA0D1EA237FEC3	false	sufficient binding region:316-554(IPR005467)	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	-
uniprotkb:P23545	uniprotkb:P23545	intact:EBI-2465053|ensemblbacteria:CAB14870	intact:EBI-2465053|ensemblbacteria:CAB14870	psi-mi:phor_bacsu(display_long)|uniprotkb:phoR(gene name)|psi-mi:phoR(display_short)|uniprotkb:BSU29100(locus name)	psi-mi:phor_bacsu(display_long)|uniprotkb:phoR(gene name)|psi-mi:phoR(display_short)|uniprotkb:BSU29100(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Casino et al. (2009)	imex:IM-12095|pubmed:19800110	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2465097|imex:IM-12095-5	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_390788.1|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|rcsb pdb:3CWF|interpro:IPR031967|refseq:WP_004398493.1|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890|ensemblbacteria:BSU_29100(gene)|ensemblbacteria:CAB14870(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|go:"GO:0046777"(protein autophosphorylation)	refseq:NP_390788.1|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|rcsb pdb:3CWF|interpro:IPR031967|refseq:WP_004398493.1|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890|ensemblbacteria:BSU_29100(gene)|ensemblbacteria:CAB14870(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|go:"GO:0046777"(protein autophosphorylation)	go:"GO:0046777"(protein autophosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:Fig. 5F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/10/21	2014/10/16	rogid:JdKeaECQ9MsqhBiVOFg5ErFuTtQ224308	rogid:JdKeaECQ9MsqhBiVOFg5ErFuTtQ224308	intact-crc:2C4DF487AC5F9188|rigid:9ET49fS8rylvIvSp+69KF+xzqac	false	-	sufficient binding region:316-554|his tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:A0A0H3K900	uniprotkb:A0A0H3K900	intact:EBI-2465150|ensemblbacteria:BAF67857	intact:EBI-2465150|ensemblbacteria:BAF67857	psi-mi:a0a0h3k900_staae(display_long)|uniprotkb:phoR(gene name)|psi-mi:phoR(display_short)|uniprotkb:NWMN_1585(locus name)	psi-mi:a0a0h3k900_staae(display_long)|uniprotkb:phoR(gene name)|psi-mi:phoR(display_short)|uniprotkb:NWMN_1585(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Casino et al. (2009)	imex:IM-12095|pubmed:19800110	taxid:426430(staae)|taxid:426430("Staphylococcus aureus (strain Newman)")	taxid:426430(staae)|taxid:426430("Staphylococcus aureus (strain Newman)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2465186|imex:IM-12095-6	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:A6QHM5(uniprot-removed-ac)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890|ensemblbacteria:BAF67857(transcript)|ensemblbacteria:NWMN_1585(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)	uniprotkb:A6QHM5(uniprot-removed-ac)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890|ensemblbacteria:BAF67857(transcript)|ensemblbacteria:NWMN_1585(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)	go:"GO:0046777"(protein autophosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:Fig. 5F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/10/21	2014/10/16	rogid:f1Y/+UDZ3WsP2yvsjJf94FntkZw426430	rogid:f1Y/+UDZ3WsP2yvsjJf94FntkZw426430	intact-crc:884CC1B1CF6E4A01|rigid:O+2gQCm/fNFqM/oO4zzrGNMvqeA	false	sufficient binding region:316-554(IPR005467)	sufficient binding region:316-554(IPR005467)|his tag:n-n|mutation:456-456	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q9WZV7	uniprotkb:Q9WYT9	intact:EBI-2464828|uniprotkb:G4FCX1|ensemblbacteria:AAD35935	intact:EBI-2464826|uniprotkb:G4FE02|ensemblbacteria:AAD35552	psi-mi:q9wzv7_thema(display_long)|uniprotkb:TM_0853(locus name)	psi-mi:q9wyt9_thema(display_long)|uniprotkb:TM_0468(locus name)	psi-mi:"MI:0841"(phosphotransferase assay)	Casino et al. (2009)	imex:IM-12095|pubmed:19800110	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	psi-mi:"MI:0844"(phosphotransfer reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2464985|imex:IM-12095-7	-	-	psi-mi:"MI:0842"(phosphate donor)	psi-mi:"MI:0843"(phosphate acceptor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_228662.1|refseq:WP_004080773.1|dip:DIP-54544N|ensemblbacteria:AAD35935(transcript)|ensemblbacteria:TM_0853(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:2C2A|rcsb pdb:3DGE|rcsb pdb:4JAS|rcsb pdb:4JAU|rcsb pdb:4JAV|rcsb pdb:4KP4|rcsb pdb:5UHT|rcsb pdb:6AZR|rcsb pdb:6RFV|rcsb pdb:6RGY|rcsb pdb:6RGZ|rcsb pdb:6RH0|rcsb pdb:6RH1|rcsb pdb:6RH2|rcsb pdb:6RH7|rcsb pdb:6RH8	refseq:NP_228278.1|refseq:WP_004081498.1|dip:DIP-54543N|ensemblbacteria:AAD35552(transcript)|ensemblbacteria:TM_0468(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0046872"(metal ion binding)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|rcsb pdb:3DGE|rcsb pdb:3DGF|rcsb pdb:3GL9|rcsb pdb:4JA2|rcsb pdb:4JAS|rcsb pdb:4JAV|rcsb pdb:5UHT|rcsb pdb:6AZR|rcsb pdb:6RFV|rcsb pdb:6RGY|rcsb pdb:6RGZ|rcsb pdb:6RH0|rcsb pdb:6RH1|rcsb pdb:6RH7|rcsb pdb:6RH8|rcsb pdb:6RH2	go:"GO:0016772"(transferase activity, transferring phosphorus-containing groups)	-	-	figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/10/21	2014/10/16	rogid:j+CHLIKfJUS5ZjDDg8REwHnTJDY243274	rogid:CP5OYhveeLzc1oa71/pfzAOfw9w243274	intact-crc:AAC870ED630921BA|rigid:+/Jt8vvXHDBBGmkjcxxp1kyMSDI	false	mutation disrupting interaction:272-272|mutation disrupting interaction:267-267|sufficient binding region:232-489(IPR005467)	mutation disrupting interaction:17-17|mutation disrupting interaction:20-20	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9WZV7	uniprotkb:Q9WYT9	intact:EBI-2464828|uniprotkb:G4FCX1|ensemblbacteria:AAD35935	intact:EBI-2464826|uniprotkb:G4FE02|ensemblbacteria:AAD35552	psi-mi:q9wzv7_thema(display_long)|uniprotkb:TM_0853(locus name)	psi-mi:q9wyt9_thema(display_long)|uniprotkb:TM_0468(locus name)	psi-mi:"MI:0841"(phosphotransferase assay)	Casino et al. (2009)	imex:IM-12095|pubmed:19800110	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	psi-mi:"MI:0844"(phosphotransfer reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2465005|imex:IM-12095-8	-	-	psi-mi:"MI:0842"(phosphate donor)	psi-mi:"MI:0842"(phosphate donor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_228662.1|refseq:WP_004080773.1|dip:DIP-54544N|ensemblbacteria:AAD35935(transcript)|ensemblbacteria:TM_0853(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:2C2A|rcsb pdb:3DGE|rcsb pdb:4JAS|rcsb pdb:4JAU|rcsb pdb:4JAV|rcsb pdb:4KP4|rcsb pdb:5UHT|rcsb pdb:6AZR|rcsb pdb:6RFV|rcsb pdb:6RGY|rcsb pdb:6RGZ|rcsb pdb:6RH0|rcsb pdb:6RH1|rcsb pdb:6RH2|rcsb pdb:6RH7|rcsb pdb:6RH8	refseq:NP_228278.1|refseq:WP_004081498.1|dip:DIP-54543N|ensemblbacteria:AAD35552(transcript)|ensemblbacteria:TM_0468(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0046872"(metal ion binding)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|rcsb pdb:3DGE|rcsb pdb:3DGF|rcsb pdb:3GL9|rcsb pdb:4JA2|rcsb pdb:4JAS|rcsb pdb:4JAV|rcsb pdb:5UHT|rcsb pdb:6AZR|rcsb pdb:6RFV|rcsb pdb:6RGY|rcsb pdb:6RGZ|rcsb pdb:6RH0|rcsb pdb:6RH1|rcsb pdb:6RH7|rcsb pdb:6RH8|rcsb pdb:6RH2	go:"GO:0016772"(transferase activity, transferring phosphorus-containing groups)	-	-	figure legend:Fig. 3D, Supp. Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/10/21	2014/10/16	rogid:j+CHLIKfJUS5ZjDDg8REwHnTJDY243274	rogid:CP5OYhveeLzc1oa71/pfzAOfw9w243274	intact-crc:C0D815F53CC8BF18|rigid:+/Jt8vvXHDBBGmkjcxxp1kyMSDI	false	mutation disrupting interaction:272-272|mutation disrupting interaction:267-267|sufficient binding region:232-489(IPR005467)|mutation:260-260	mutation disrupting interaction:17-17|mutation disrupting interaction:20-20	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)