#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q96T88 uniprotkb:Q9Y6K1 intact:EBI-1548946|uniprotkb:Q8J022|uniprotkb:Q9H6S6|uniprotkb:Q9P115|uniprotkb:Q9P1U7|uniprotkb:A0JBR2|uniprotkb:A8K024|uniprotkb:B2RBA9|uniprotkb:Q2HIX7|ensembl:ENSP00000478348|ensembl:ENSP00000478601|ensembl:ENSP00000484739|ensembl:ENSP00000485604|ensembl:ENSP00000498698 intact:EBI-923653|uniprotkb:Q8WXU9|uniprotkb:Q86XF5|uniprotkb:Q8IZV0|uniprotkb:Q86TE8|uniprotkb:E9PEB8|ensembl:ENSP00000264709|ensembl:ENSP00000324375 psi-mi:uhrf1_human(display_long)|uniprotkb:UHRF1(gene name)|psi-mi:UHRF1(display_short)|uniprotkb:ICBP90(gene name synonym)|uniprotkb:NP95(gene name synonym)|uniprotkb:RNF106(gene name synonym)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 1(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 1(gene name synonym)|uniprotkb:Inverted CCAAT box-binding protein of 90 kDa(gene name synonym)|uniprotkb:Transcription factor ICBP90(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np95(gene name synonym)|uniprotkb:Nuclear protein 95(gene name synonym)|uniprotkb:RING finger protein 106(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF1(gene name synonym) psi-mi:dnm3a_human(display_long)|uniprotkb:DNMT3A(gene name)|psi-mi:DNMT3A(display_short)|uniprotkb:DNA methyltransferase HsaIIIA(gene name synonym)|uniprotkb:Cysteine methyltransferase DNMT3A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Meilinger et al. (2009) pubmed:19798101|imex:IM-13880|mint:MINT-7296296|doi:10.1038/embor.2009.201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7271571|mint:MINT-7296314|imex:IM-13880-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276979.1|refseq:NP_001276980.1|refseq:NP_001276981.1|refseq:NP_037414.3|refseq:NP_001041666.1|ensembl:ENSG00000276043(gene)|ensembl:ENST00000612630(transcript)|ensembl:ENST00000615884(transcript)|ensembl:ENST00000616255(transcript)|ensembl:ENST00000624301(transcript)|ensembl:ENST00000650932(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR000626(Ubiquitin)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|mint:Q96T88|rcsb pdb:2FAZ|rcsb pdb:2L3R|rcsb pdb:2LGG|rcsb pdb:2LGK|rcsb pdb:2LGL|rcsb pdb:2PB7|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3BI7|rcsb pdb:3CLZ|rcsb pdb:3DB3|rcsb pdb:3DB4|rcsb pdb:3DWH|rcsb pdb:3FL2|rcsb pdb:3SHB|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3SOX|rcsb pdb:3T6R|rcsb pdb:3ZVY|rcsb pdb:3ZVZ|rcsb pdb:4GY5|rcsb pdb:4QQD|rcsb pdb:5C6D|rcsb pdb:5IAY|rcsb pdb:5XPI|rcsb pdb:5YY9|rcsb pdb:5YYA|rcsb pdb:6B9M|rcsb pdb:6IIW|rcsb pdb:6VCS|rcsb pdb:6VED|rcsb pdb:6VYJ|rcsb pdb:6W92|reactome:R-HSA-5334118|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-7296318(identity) refseq:NP_001307821.1|refseq:NP_072046.2|refseq:NP_783328.1|refseq:NP_783329.1|refseq:XP_016859015.1|refseq:XP_016859016.1|refseq:XP_011530969.1|refseq:NP_001307822.1|refseq:NP_715640.2|refseq:XP_005264232.1|dip:DIP-38004N|refseq:XP_005264234.1|ensembl:ENSG00000119772(gene)|ensembl:ENST00000264709(transcript)|ensembl:ENST00000321117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010288"(response to lead ion)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0033189"(response to vitamin A)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030487|interpro:IPR040552|interpro:IPR044108|mint:Q9Y6K1|rcsb pdb:2QRV|rcsb pdb:3A1A|rcsb pdb:3A1B|rcsb pdb:3LLR|rcsb pdb:3SVM|rcsb pdb:4QBQ|rcsb pdb:4QBR|rcsb pdb:4QBS|rcsb pdb:4U7P|rcsb pdb:4U7T|rcsb pdb:5YX2|rcsb pdb:6BRR|rcsb pdb:6F57|rcsb pdb:6PA7|rcsb pdb:6W89|rcsb pdb:6W8B|rcsb pdb:6W8D|rcsb pdb:6W8J|reactome:R-HSA-212300|reactome:R-HSA-3214858|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|mint:MINT-7296316(identity) - - - figure legend:f1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-embryonic_stem_ cells)|taxid:9606("Human-embryonic_stem_ cells (es cells)") - 2009/11/05 2014/10/16 rogid:AbWLjSoRl82HTcjZlG4DRavDdGc9606 rogid:rnq1Yv4tlQ1t9JXS3CfMmTlcPKE9606 intact-crc:2D10D5ACD9988F89|rigid:lGKozt8rBVJaLmUcGwP3G6GJ+5U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q96T88 uniprotkb:Q9UBC3 intact:EBI-1548946|uniprotkb:Q8J022|uniprotkb:Q9H6S6|uniprotkb:Q9P115|uniprotkb:Q9P1U7|uniprotkb:A0JBR2|uniprotkb:A8K024|uniprotkb:B2RBA9|uniprotkb:Q2HIX7|ensembl:ENSP00000478348|ensembl:ENSP00000478601|ensembl:ENSP00000484739|ensembl:ENSP00000485604|ensembl:ENSP00000498698 intact:EBI-80125|uniprotkb:Q9UBD4|uniprotkb:Q9UJQ5|uniprotkb:Q9UKA6|uniprotkb:Q9UNE5|uniprotkb:Q9Y5R9|uniprotkb:Q9Y5S0|intact:EBI-28970262|ensembl:ENSP00000328547|uniprotkb:A2A2E2|uniprotkb:E1P5M6|uniprotkb:E1P5M7|uniprotkb:B4DSM8|uniprotkb:B4DSU1|uniprotkb:E7EN63|uniprotkb:E9PBF2 psi-mi:uhrf1_human(display_long)|uniprotkb:UHRF1(gene name)|psi-mi:UHRF1(display_short)|uniprotkb:ICBP90(gene name synonym)|uniprotkb:NP95(gene name synonym)|uniprotkb:RNF106(gene name synonym)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 1(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 1(gene name synonym)|uniprotkb:Inverted CCAAT box-binding protein of 90 kDa(gene name synonym)|uniprotkb:Transcription factor ICBP90(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np95(gene name synonym)|uniprotkb:Nuclear protein 95(gene name synonym)|uniprotkb:RING finger protein 106(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF1(gene name synonym) psi-mi:dnm3b_human(display_long)|uniprotkb:DNMT3B(gene name)|psi-mi:DNMT3B(display_short)|uniprotkb:DNA methyltransferase HsaIIIB(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Meilinger et al. (2009) pubmed:19798101|imex:IM-13880|mint:MINT-7296296|doi:10.1038/embor.2009.201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7271571|mint:MINT-7296314|imex:IM-13880-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276979.1|refseq:NP_001276980.1|refseq:NP_001276981.1|refseq:NP_037414.3|refseq:NP_001041666.1|ensembl:ENSG00000276043(gene)|ensembl:ENST00000612630(transcript)|ensembl:ENST00000615884(transcript)|ensembl:ENST00000616255(transcript)|ensembl:ENST00000624301(transcript)|ensembl:ENST00000650932(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR000626(Ubiquitin)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|mint:Q96T88|rcsb pdb:2FAZ|rcsb pdb:2L3R|rcsb pdb:2LGG|rcsb pdb:2LGK|rcsb pdb:2LGL|rcsb pdb:2PB7|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3BI7|rcsb pdb:3CLZ|rcsb pdb:3DB3|rcsb pdb:3DB4|rcsb pdb:3DWH|rcsb pdb:3FL2|rcsb pdb:3SHB|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3SOX|rcsb pdb:3T6R|rcsb pdb:3ZVY|rcsb pdb:3ZVZ|rcsb pdb:4GY5|rcsb pdb:4QQD|rcsb pdb:5C6D|rcsb pdb:5IAY|rcsb pdb:5XPI|rcsb pdb:5YY9|rcsb pdb:5YYA|rcsb pdb:6B9M|rcsb pdb:6IIW|rcsb pdb:6VCS|rcsb pdb:6VED|rcsb pdb:6VYJ|rcsb pdb:6W92|reactome:R-HSA-5334118|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-7296318(identity) ensembl:ENSG00000088305(gene)|ensembl:ENST00000328111(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0009008"(DNA-methyltransferase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014823"(response to activity)|go:"GO:0031000"(response to caffeine)|go:"GO:0032355"(response to estradiol)|go:"GO:0033189"(response to vitamin A)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030488|interpro:IPR040552|mint:Q9UBC3|rcsb pdb:3FLG|rcsb pdb:3QKJ|rcsb pdb:5CIU|rcsb pdb:5NR3|rcsb pdb:5NRR|rcsb pdb:5NRV|rcsb pdb:5NV0|rcsb pdb:5NV2|rcsb pdb:5NV7|rcsb pdb:5NVO|rcsb pdb:6KDA|rcsb pdb:6KDB|rcsb pdb:6KDL|rcsb pdb:6KDP|rcsb pdb:6KDT|rcsb pdb:6PA7|rcsb pdb:6R3E|rcsb pdb:6U8P|rcsb pdb:6U8V|rcsb pdb:6U8W|rcsb pdb:6U8X|rcsb pdb:5NRS|rcsb pdb:6U90|rcsb pdb:6U91|reactome:R-HSA-212300|reactome:R-HSA-427413|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|ensembl:ENST00000353855|ensembl:ENSP00000313397|ensembl:ENST00000443239|ensembl:ENSP00000403169|ensembl:ENST00000456297|ensembl:ENSP00000412305|ensembl:ENST00000201963|ensembl:ENSP00000201963|ensembl:ENSP00000328547|ensembl:ENST00000348286|ensembl:ENSP00000337764|refseq:NP_001193984.1|refseq:NP_001193985.1|refseq:NP_008823.1|refseq:NP_787044.1|refseq:NP_787045.1|refseq:NP_787046.1|dip:DIP-30000N|mint:MINT-7302695(identity) - - - figure legend:f1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-embryonic_stem_ cells)|taxid:9606("Human-embryonic_stem_ cells (es cells)") - 2009/11/05 2014/10/16 rogid:AbWLjSoRl82HTcjZlG4DRavDdGc9606 rogid:xxbu/yvuQ1KnhVE/FdTh9CyA6jw9606 intact-crc:2D10D5ACD9988F89|rigid:lGKozt8rBVJaLmUcGwP3G6GJ+5U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q96T88 uniprotkb:Q9Y6K1 intact:EBI-1548946|uniprotkb:Q8J022|uniprotkb:Q9H6S6|uniprotkb:Q9P115|uniprotkb:Q9P1U7|uniprotkb:A0JBR2|uniprotkb:A8K024|uniprotkb:B2RBA9|uniprotkb:Q2HIX7|ensembl:ENSP00000478348|ensembl:ENSP00000478601|ensembl:ENSP00000484739|ensembl:ENSP00000485604|ensembl:ENSP00000498698 intact:EBI-923653|uniprotkb:Q8WXU9|uniprotkb:Q86XF5|uniprotkb:Q8IZV0|uniprotkb:Q86TE8|uniprotkb:E9PEB8|ensembl:ENSP00000264709|ensembl:ENSP00000324375 psi-mi:uhrf1_human(display_long)|uniprotkb:UHRF1(gene name)|psi-mi:UHRF1(display_short)|uniprotkb:ICBP90(gene name synonym)|uniprotkb:NP95(gene name synonym)|uniprotkb:RNF106(gene name synonym)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 1(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 1(gene name synonym)|uniprotkb:Inverted CCAAT box-binding protein of 90 kDa(gene name synonym)|uniprotkb:Transcription factor ICBP90(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np95(gene name synonym)|uniprotkb:Nuclear protein 95(gene name synonym)|uniprotkb:RING finger protein 106(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF1(gene name synonym) psi-mi:dnm3a_human(display_long)|uniprotkb:DNMT3A(gene name)|psi-mi:DNMT3A(display_short)|uniprotkb:DNA methyltransferase HsaIIIA(gene name synonym)|uniprotkb:Cysteine methyltransferase DNMT3A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Meilinger et al. (2009) pubmed:19798101|imex:IM-13880|mint:MINT-7296296|doi:10.1038/embor.2009.201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7271675|mint:MINT-7296322|imex:IM-13880-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276979.1|refseq:NP_001276980.1|refseq:NP_001276981.1|refseq:NP_037414.3|refseq:NP_001041666.1|ensembl:ENSG00000276043(gene)|ensembl:ENST00000612630(transcript)|ensembl:ENST00000615884(transcript)|ensembl:ENST00000616255(transcript)|ensembl:ENST00000624301(transcript)|ensembl:ENST00000650932(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR000626(Ubiquitin)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|mint:Q96T88|rcsb pdb:2FAZ|rcsb pdb:2L3R|rcsb pdb:2LGG|rcsb pdb:2LGK|rcsb pdb:2LGL|rcsb pdb:2PB7|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3BI7|rcsb pdb:3CLZ|rcsb pdb:3DB3|rcsb pdb:3DB4|rcsb pdb:3DWH|rcsb pdb:3FL2|rcsb pdb:3SHB|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3SOX|rcsb pdb:3T6R|rcsb pdb:3ZVY|rcsb pdb:3ZVZ|rcsb pdb:4GY5|rcsb pdb:4QQD|rcsb pdb:5C6D|rcsb pdb:5IAY|rcsb pdb:5XPI|rcsb pdb:5YY9|rcsb pdb:5YYA|rcsb pdb:6B9M|rcsb pdb:6IIW|rcsb pdb:6VCS|rcsb pdb:6VED|rcsb pdb:6VYJ|rcsb pdb:6W92|reactome:R-HSA-5334118|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-7296326(identity) refseq:NP_001307821.1|refseq:NP_072046.2|refseq:NP_783328.1|refseq:NP_783329.1|refseq:XP_016859015.1|refseq:XP_016859016.1|refseq:XP_011530969.1|refseq:NP_001307822.1|refseq:NP_715640.2|refseq:XP_005264232.1|dip:DIP-38004N|refseq:XP_005264234.1|ensembl:ENSG00000119772(gene)|ensembl:ENST00000264709(transcript)|ensembl:ENST00000321117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010288"(response to lead ion)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0033189"(response to vitamin A)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030487|interpro:IPR040552|interpro:IPR044108|mint:Q9Y6K1|rcsb pdb:2QRV|rcsb pdb:3A1A|rcsb pdb:3A1B|rcsb pdb:3LLR|rcsb pdb:3SVM|rcsb pdb:4QBQ|rcsb pdb:4QBR|rcsb pdb:4QBS|rcsb pdb:4U7P|rcsb pdb:4U7T|rcsb pdb:5YX2|rcsb pdb:6BRR|rcsb pdb:6F57|rcsb pdb:6PA7|rcsb pdb:6W89|rcsb pdb:6W8B|rcsb pdb:6W8D|rcsb pdb:6W8J|reactome:R-HSA-212300|reactome:R-HSA-3214858|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|mint:MINT-7296324(identity) - - - comment:homomint|comment:mint|figure legend:f1c sf2b sf2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2009/11/05 2014/10/16 rogid:AbWLjSoRl82HTcjZlG4DRavDdGc9606 rogid:rnq1Yv4tlQ1t9JXS3CfMmTlcPKE9606 intact-crc:A31EDE8B27EF72CF|rigid:mebVOSa1jY1DcK+vvFibgMvyUSs false his tag:?-?(MINT-7296333)|binding-associated region:1-310(MINT-7296438) binding-associated region:1-629(MINT-7296435)|green fluorescent protein tag:?-?(MINT-7296330) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96T88 uniprotkb:Q9UBC3 intact:EBI-1548946|uniprotkb:Q8J022|uniprotkb:Q9H6S6|uniprotkb:Q9P115|uniprotkb:Q9P1U7|uniprotkb:A0JBR2|uniprotkb:A8K024|uniprotkb:B2RBA9|uniprotkb:Q2HIX7|ensembl:ENSP00000478348|ensembl:ENSP00000478601|ensembl:ENSP00000484739|ensembl:ENSP00000485604|ensembl:ENSP00000498698 intact:EBI-80125|uniprotkb:Q9UBD4|uniprotkb:Q9UJQ5|uniprotkb:Q9UKA6|uniprotkb:Q9UNE5|uniprotkb:Q9Y5R9|uniprotkb:Q9Y5S0|intact:EBI-28970262|ensembl:ENSP00000328547|uniprotkb:A2A2E2|uniprotkb:E1P5M6|uniprotkb:E1P5M7|uniprotkb:B4DSM8|uniprotkb:B4DSU1|uniprotkb:E7EN63|uniprotkb:E9PBF2 psi-mi:uhrf1_human(display_long)|uniprotkb:UHRF1(gene name)|psi-mi:UHRF1(display_short)|uniprotkb:ICBP90(gene name synonym)|uniprotkb:NP95(gene name synonym)|uniprotkb:RNF106(gene name synonym)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 1(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 1(gene name synonym)|uniprotkb:Inverted CCAAT box-binding protein of 90 kDa(gene name synonym)|uniprotkb:Transcription factor ICBP90(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np95(gene name synonym)|uniprotkb:Nuclear protein 95(gene name synonym)|uniprotkb:RING finger protein 106(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF1(gene name synonym) psi-mi:dnm3b_human(display_long)|uniprotkb:DNMT3B(gene name)|psi-mi:DNMT3B(display_short)|uniprotkb:DNA methyltransferase HsaIIIB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Meilinger et al. (2009) pubmed:19798101|imex:IM-13880|mint:MINT-7296296|doi:10.1038/embor.2009.201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7271741|mint:MINT-7296336|imex:IM-13880-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276979.1|refseq:NP_001276980.1|refseq:NP_001276981.1|refseq:NP_037414.3|refseq:NP_001041666.1|ensembl:ENSG00000276043(gene)|ensembl:ENST00000612630(transcript)|ensembl:ENST00000615884(transcript)|ensembl:ENST00000616255(transcript)|ensembl:ENST00000624301(transcript)|ensembl:ENST00000650932(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR000626(Ubiquitin)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|mint:Q96T88|rcsb pdb:2FAZ|rcsb pdb:2L3R|rcsb pdb:2LGG|rcsb pdb:2LGK|rcsb pdb:2LGL|rcsb pdb:2PB7|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3BI7|rcsb pdb:3CLZ|rcsb pdb:3DB3|rcsb pdb:3DB4|rcsb pdb:3DWH|rcsb pdb:3FL2|rcsb pdb:3SHB|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3SOX|rcsb pdb:3T6R|rcsb pdb:3ZVY|rcsb pdb:3ZVZ|rcsb pdb:4GY5|rcsb pdb:4QQD|rcsb pdb:5C6D|rcsb pdb:5IAY|rcsb pdb:5XPI|rcsb pdb:5YY9|rcsb pdb:5YYA|rcsb pdb:6B9M|rcsb pdb:6IIW|rcsb pdb:6VCS|rcsb pdb:6VED|rcsb pdb:6VYJ|rcsb pdb:6W92|reactome:R-HSA-5334118|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-7296338(identity) ensembl:ENSG00000088305(gene)|ensembl:ENST00000328111(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0009008"(DNA-methyltransferase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014823"(response to activity)|go:"GO:0031000"(response to caffeine)|go:"GO:0032355"(response to estradiol)|go:"GO:0033189"(response to vitamin A)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030488|interpro:IPR040552|mint:Q9UBC3|rcsb pdb:3FLG|rcsb pdb:3QKJ|rcsb pdb:5CIU|rcsb pdb:5NR3|rcsb pdb:5NRR|rcsb pdb:5NRV|rcsb pdb:5NV0|rcsb pdb:5NV2|rcsb pdb:5NV7|rcsb pdb:5NVO|rcsb pdb:6KDA|rcsb pdb:6KDB|rcsb pdb:6KDL|rcsb pdb:6KDP|rcsb pdb:6KDT|rcsb pdb:6PA7|rcsb pdb:6R3E|rcsb pdb:6U8P|rcsb pdb:6U8V|rcsb pdb:6U8W|rcsb pdb:6U8X|rcsb pdb:5NRS|rcsb pdb:6U90|rcsb pdb:6U91|reactome:R-HSA-212300|reactome:R-HSA-427413|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|ensembl:ENST00000353855|ensembl:ENSP00000313397|ensembl:ENST00000443239|ensembl:ENSP00000403169|ensembl:ENST00000456297|ensembl:ENSP00000412305|ensembl:ENST00000201963|ensembl:ENSP00000201963|ensembl:ENSP00000328547|ensembl:ENST00000348286|ensembl:ENSP00000337764|refseq:NP_001193984.1|refseq:NP_001193985.1|refseq:NP_008823.1|refseq:NP_787044.1|refseq:NP_787045.1|refseq:NP_787046.1|dip:DIP-30000N|mint:MINT-7296342(identity) - - - comment:homomint|comment:mint|figure legend:f1c sf2b sf2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2009/11/05 2014/10/16 rogid:AbWLjSoRl82HTcjZlG4DRavDdGc9606 rogid:xxbu/yvuQ1KnhVE/FdTh9CyA6jw9606 intact-crc:74F1CDE6CD7524D2|rigid:CH/Jr54jUjCu+ccmnxjDtPfFrI4 false binding-associated region:1-310(MINT-7296463)|his tag:?-?(MINT-7296339) green fluorescent protein tag:?-?(MINT-7296343)|binding-associated region:1-580(MINT-7296460) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y6K1 uniprotkb:Q96T88 intact:EBI-923653|uniprotkb:Q8WXU9|uniprotkb:Q86XF5|uniprotkb:Q8IZV0|uniprotkb:Q86TE8|uniprotkb:E9PEB8|ensembl:ENSP00000264709|ensembl:ENSP00000324375 intact:EBI-1548946|uniprotkb:Q8J022|uniprotkb:Q9H6S6|uniprotkb:Q9P115|uniprotkb:Q9P1U7|uniprotkb:A0JBR2|uniprotkb:A8K024|uniprotkb:B2RBA9|uniprotkb:Q2HIX7|ensembl:ENSP00000478348|ensembl:ENSP00000478601|ensembl:ENSP00000484739|ensembl:ENSP00000485604|ensembl:ENSP00000498698 psi-mi:dnm3a_human(display_long)|uniprotkb:DNMT3A(gene name)|psi-mi:DNMT3A(display_short)|uniprotkb:DNA methyltransferase HsaIIIA(gene name synonym)|uniprotkb:Cysteine methyltransferase DNMT3A(gene name synonym) psi-mi:uhrf1_human(display_long)|uniprotkb:UHRF1(gene name)|psi-mi:UHRF1(display_short)|uniprotkb:ICBP90(gene name synonym)|uniprotkb:NP95(gene name synonym)|uniprotkb:RNF106(gene name synonym)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 1(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 1(gene name synonym)|uniprotkb:Inverted CCAAT box-binding protein of 90 kDa(gene name synonym)|uniprotkb:Transcription factor ICBP90(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np95(gene name synonym)|uniprotkb:Nuclear protein 95(gene name synonym)|uniprotkb:RING finger protein 106(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Meilinger et al. (2009) pubmed:19798101|imex:IM-13880|mint:MINT-7296296|doi:10.1038/embor.2009.201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7271834|mint:MINT-7296441|imex:IM-13880-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001307821.1|refseq:NP_072046.2|refseq:NP_783328.1|refseq:NP_783329.1|refseq:XP_016859015.1|refseq:XP_016859016.1|refseq:XP_011530969.1|refseq:NP_001307822.1|refseq:NP_715640.2|refseq:XP_005264232.1|dip:DIP-38004N|refseq:XP_005264234.1|ensembl:ENSG00000119772(gene)|ensembl:ENST00000264709(transcript)|ensembl:ENST00000321117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010288"(response to lead ion)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0033189"(response to vitamin A)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030487|interpro:IPR040552|interpro:IPR044108|mint:Q9Y6K1|rcsb pdb:2QRV|rcsb pdb:3A1A|rcsb pdb:3A1B|rcsb pdb:3LLR|rcsb pdb:3SVM|rcsb pdb:4QBQ|rcsb pdb:4QBR|rcsb pdb:4QBS|rcsb pdb:4U7P|rcsb pdb:4U7T|rcsb pdb:5YX2|rcsb pdb:6BRR|rcsb pdb:6F57|rcsb pdb:6PA7|rcsb pdb:6W89|rcsb pdb:6W8B|rcsb pdb:6W8D|rcsb pdb:6W8J|reactome:R-HSA-212300|reactome:R-HSA-3214858|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|mint:MINT-7296449(identity) refseq:NP_001276979.1|refseq:NP_001276980.1|refseq:NP_001276981.1|refseq:NP_037414.3|refseq:NP_001041666.1|ensembl:ENSG00000276043(gene)|ensembl:ENST00000612630(transcript)|ensembl:ENST00000615884(transcript)|ensembl:ENST00000616255(transcript)|ensembl:ENST00000624301(transcript)|ensembl:ENST00000650932(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR000626(Ubiquitin)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|mint:Q96T88|rcsb pdb:2FAZ|rcsb pdb:2L3R|rcsb pdb:2LGG|rcsb pdb:2LGK|rcsb pdb:2LGL|rcsb pdb:2PB7|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3BI7|rcsb pdb:3CLZ|rcsb pdb:3DB3|rcsb pdb:3DB4|rcsb pdb:3DWH|rcsb pdb:3FL2|rcsb pdb:3SHB|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3SOX|rcsb pdb:3T6R|rcsb pdb:3ZVY|rcsb pdb:3ZVZ|rcsb pdb:4GY5|rcsb pdb:4QQD|rcsb pdb:5C6D|rcsb pdb:5IAY|rcsb pdb:5XPI|rcsb pdb:5YY9|rcsb pdb:5YYA|rcsb pdb:6B9M|rcsb pdb:6IIW|rcsb pdb:6VCS|rcsb pdb:6VED|rcsb pdb:6VYJ|rcsb pdb:6W92|reactome:R-HSA-5334118|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-7296443(identity) - - - comment:homomint|comment:domino|comment:mint|figure legend:f1c sf2b sf2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2009/11/05 2014/10/16 rogid:rnq1Yv4tlQ1t9JXS3CfMmTlcPKE9606 rogid:AbWLjSoRl82HTcjZlG4DRavDdGc9606 intact-crc:766E34619E2B0AF5|rigid:mebVOSa1jY1DcK+vvFibgMvyUSs false green fluorescent protein tag:?-?(MINT-7296452)|binding-associated region:1-629(MINT-7296450) binding-associated region:414-586(MINT-7296444)|his tag:?-?(MINT-7296446) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P26358 uniprotkb:Q96T88 intact:EBI-719459|uniprotkb:Q9UHG5|uniprotkb:Q9ULA2|uniprotkb:Q9UMZ6|uniprotkb:A0AV63|intact:EBI-28971395|ensembl:ENSP00000345739|uniprotkb:B7ZLW6 intact:EBI-1548946|uniprotkb:Q8J022|uniprotkb:Q9H6S6|uniprotkb:Q9P115|uniprotkb:Q9P1U7|uniprotkb:A0JBR2|uniprotkb:A8K024|uniprotkb:B2RBA9|uniprotkb:Q2HIX7|ensembl:ENSP00000478348|ensembl:ENSP00000478601|ensembl:ENSP00000484739|ensembl:ENSP00000485604|ensembl:ENSP00000498698 psi-mi:dnmt1_human(display_long)|uniprotkb:CXXC9(gene name synonym)|uniprotkb:MCMT(gene name synonym)|uniprotkb:DNA methyltransferase HsaI(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 9(gene name synonym)|uniprotkb:DNMT1(gene name)|psi-mi:DNMT1(display_short)|uniprotkb:AIM(gene name synonym)|uniprotkb:DNMT(gene name synonym) psi-mi:uhrf1_human(display_long)|uniprotkb:UHRF1(gene name)|psi-mi:UHRF1(display_short)|uniprotkb:ICBP90(gene name synonym)|uniprotkb:NP95(gene name synonym)|uniprotkb:RNF106(gene name synonym)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 1(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 1(gene name synonym)|uniprotkb:Inverted CCAAT box-binding protein of 90 kDa(gene name synonym)|uniprotkb:Transcription factor ICBP90(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np95(gene name synonym)|uniprotkb:Nuclear protein 95(gene name synonym)|uniprotkb:RING finger protein 106(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Meilinger et al. (2009) pubmed:19798101|imex:IM-13880|mint:MINT-7296296|doi:10.1038/embor.2009.201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7271791|mint:MINT-7296348|imex:IM-13880-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000345739|ensembl:ENST00000359526|ensembl:ENSP00000352516|refseq:NP_001124295.1|refseq:NP_001370.1|ensembl:ENSG00000130816(gene)|ensembl:ENST00000340748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008270"(zinc ion binding)|reactome:R-HSA-427413|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|refseq:NP_001305659.1|refseq:NP_001305660.1|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009008"(DNA-methyltransferase activity)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905931"(negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR010506(DMAP1-binding)|interpro:IPR017198("DNA (cytosine-5)-methyltransferase 1")|interpro:IPR018117|interpro:IPR022702|interpro:IPR029063|interpro:IPR031303|interpro:IPR043151|mint:P26358|rcsb pdb:3EPZ|rcsb pdb:3PTA|rcsb pdb:3SWR|rcsb pdb:4WXX|rcsb pdb:4YOC|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5WVO|rcsb pdb:5YDR|rcsb pdb:6K3A|reactome:R-HSA-212300|dip:DIP-39693N|mint:MINT-7296350(identity) refseq:NP_001276979.1|refseq:NP_001276980.1|refseq:NP_001276981.1|refseq:NP_037414.3|refseq:NP_001041666.1|ensembl:ENSG00000276043(gene)|ensembl:ENST00000612630(transcript)|ensembl:ENST00000615884(transcript)|ensembl:ENST00000616255(transcript)|ensembl:ENST00000624301(transcript)|ensembl:ENST00000650932(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR000626(Ubiquitin)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|mint:Q96T88|rcsb pdb:2FAZ|rcsb pdb:2L3R|rcsb pdb:2LGG|rcsb pdb:2LGK|rcsb pdb:2LGL|rcsb pdb:2PB7|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3BI7|rcsb pdb:3CLZ|rcsb pdb:3DB3|rcsb pdb:3DB4|rcsb pdb:3DWH|rcsb pdb:3FL2|rcsb pdb:3SHB|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3SOX|rcsb pdb:3T6R|rcsb pdb:3ZVY|rcsb pdb:3ZVZ|rcsb pdb:4GY5|rcsb pdb:4QQD|rcsb pdb:5C6D|rcsb pdb:5IAY|rcsb pdb:5XPI|rcsb pdb:5YY9|rcsb pdb:5YYA|rcsb pdb:6B9M|rcsb pdb:6IIW|rcsb pdb:6VCS|rcsb pdb:6VED|rcsb pdb:6VYJ|rcsb pdb:6W92|reactome:R-HSA-5334118|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-7296354(identity) - - - figure legend:f1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2009/11/05 2014/10/16 rogid:qae3zQwGP5R/+WCWoeahDKZ/9Jg9606 rogid:AbWLjSoRl82HTcjZlG4DRavDdGc9606 intact-crc:BD66D112B628813C|rigid:wBiJs8Kh93/VQPQOw50JqAbNYjE false green fluorescent protein tag:?-?(MINT-7296351) his tag:?-?(MINT-7296355) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UBC3 uniprotkb:Q96T88 intact:EBI-80125|uniprotkb:Q9UBD4|uniprotkb:Q9UJQ5|uniprotkb:Q9UKA6|uniprotkb:Q9UNE5|uniprotkb:Q9Y5R9|uniprotkb:Q9Y5S0|intact:EBI-28970262|ensembl:ENSP00000328547|uniprotkb:A2A2E2|uniprotkb:E1P5M6|uniprotkb:E1P5M7|uniprotkb:B4DSM8|uniprotkb:B4DSU1|uniprotkb:E7EN63|uniprotkb:E9PBF2 intact:EBI-1548946|uniprotkb:Q8J022|uniprotkb:Q9H6S6|uniprotkb:Q9P115|uniprotkb:Q9P1U7|uniprotkb:A0JBR2|uniprotkb:A8K024|uniprotkb:B2RBA9|uniprotkb:Q2HIX7|ensembl:ENSP00000478348|ensembl:ENSP00000478601|ensembl:ENSP00000484739|ensembl:ENSP00000485604|ensembl:ENSP00000498698 psi-mi:dnm3b_human(display_long)|uniprotkb:DNMT3B(gene name)|psi-mi:DNMT3B(display_short)|uniprotkb:DNA methyltransferase HsaIIIB(gene name synonym) psi-mi:uhrf1_human(display_long)|uniprotkb:UHRF1(gene name)|psi-mi:UHRF1(display_short)|uniprotkb:ICBP90(gene name synonym)|uniprotkb:NP95(gene name synonym)|uniprotkb:RNF106(gene name synonym)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 1(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 1(gene name synonym)|uniprotkb:Inverted CCAAT box-binding protein of 90 kDa(gene name synonym)|uniprotkb:Transcription factor ICBP90(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np95(gene name synonym)|uniprotkb:Nuclear protein 95(gene name synonym)|uniprotkb:RING finger protein 106(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Meilinger et al. (2009) pubmed:19798101|imex:IM-13880|mint:MINT-7296296|doi:10.1038/embor.2009.201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7271896|mint:MINT-7296468|imex:IM-13880-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000088305(gene)|ensembl:ENST00000328111(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0009008"(DNA-methyltransferase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014823"(response to activity)|go:"GO:0031000"(response to caffeine)|go:"GO:0032355"(response to estradiol)|go:"GO:0033189"(response to vitamin A)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030488|interpro:IPR040552|mint:Q9UBC3|rcsb pdb:3FLG|rcsb pdb:3QKJ|rcsb pdb:5CIU|rcsb pdb:5NR3|rcsb pdb:5NRR|rcsb pdb:5NRV|rcsb pdb:5NV0|rcsb pdb:5NV2|rcsb pdb:5NV7|rcsb pdb:5NVO|rcsb pdb:6KDA|rcsb pdb:6KDB|rcsb pdb:6KDL|rcsb pdb:6KDP|rcsb pdb:6KDT|rcsb pdb:6PA7|rcsb pdb:6R3E|rcsb pdb:6U8P|rcsb pdb:6U8V|rcsb pdb:6U8W|rcsb pdb:6U8X|rcsb pdb:5NRS|rcsb pdb:6U90|rcsb pdb:6U91|reactome:R-HSA-212300|reactome:R-HSA-427413|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|ensembl:ENST00000353855|ensembl:ENSP00000313397|ensembl:ENST00000443239|ensembl:ENSP00000403169|ensembl:ENST00000456297|ensembl:ENSP00000412305|ensembl:ENST00000201963|ensembl:ENSP00000201963|ensembl:ENSP00000328547|ensembl:ENST00000348286|ensembl:ENSP00000337764|refseq:NP_001193984.1|refseq:NP_001193985.1|refseq:NP_008823.1|refseq:NP_787044.1|refseq:NP_787045.1|refseq:NP_787046.1|dip:DIP-30000N|mint:MINT-7296470(identity) refseq:NP_001276979.1|refseq:NP_001276980.1|refseq:NP_001276981.1|refseq:NP_037414.3|refseq:NP_001041666.1|ensembl:ENSG00000276043(gene)|ensembl:ENST00000612630(transcript)|ensembl:ENST00000615884(transcript)|ensembl:ENST00000616255(transcript)|ensembl:ENST00000624301(transcript)|ensembl:ENST00000650932(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR000626(Ubiquitin)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|mint:Q96T88|rcsb pdb:2FAZ|rcsb pdb:2L3R|rcsb pdb:2LGG|rcsb pdb:2LGK|rcsb pdb:2LGL|rcsb pdb:2PB7|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3BI7|rcsb pdb:3CLZ|rcsb pdb:3DB3|rcsb pdb:3DB4|rcsb pdb:3DWH|rcsb pdb:3FL2|rcsb pdb:3SHB|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3SOX|rcsb pdb:3T6R|rcsb pdb:3ZVY|rcsb pdb:3ZVZ|rcsb pdb:4GY5|rcsb pdb:4QQD|rcsb pdb:5C6D|rcsb pdb:5IAY|rcsb pdb:5XPI|rcsb pdb:5YY9|rcsb pdb:5YYA|rcsb pdb:6B9M|rcsb pdb:6IIW|rcsb pdb:6VCS|rcsb pdb:6VED|rcsb pdb:6VYJ|rcsb pdb:6W92|reactome:R-HSA-5334118|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-7296476(identity) - - - comment:homomint|comment:mint|figure legend:f1c sf2b sf2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2009/11/05 2014/10/16 rogid:xxbu/yvuQ1KnhVE/FdTh9CyA6jw9606 rogid:AbWLjSoRl82HTcjZlG4DRavDdGc9606 intact-crc:005A7E1A9BB99C3D|rigid:CH/Jr54jUjCu+ccmnxjDtPfFrI4 false green fluorescent protein tag:?-?(MINT-7296473)|binding-associated region:1-580(MINT-7296471) his tag:?-?(MINT-7296479)|binding-associated region:414-586(MINT-7296477) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96T88 uniprotkb:Q9Y6K1 intact:EBI-1548946|uniprotkb:Q8J022|uniprotkb:Q9H6S6|uniprotkb:Q9P115|uniprotkb:Q9P1U7|uniprotkb:A0JBR2|uniprotkb:A8K024|uniprotkb:B2RBA9|uniprotkb:Q2HIX7|ensembl:ENSP00000478348|ensembl:ENSP00000478601|ensembl:ENSP00000484739|ensembl:ENSP00000485604|ensembl:ENSP00000498698 intact:EBI-923653|uniprotkb:Q8WXU9|uniprotkb:Q86XF5|uniprotkb:Q8IZV0|uniprotkb:Q86TE8|uniprotkb:E9PEB8|ensembl:ENSP00000264709|ensembl:ENSP00000324375 psi-mi:uhrf1_human(display_long)|uniprotkb:UHRF1(gene name)|psi-mi:UHRF1(display_short)|uniprotkb:ICBP90(gene name synonym)|uniprotkb:NP95(gene name synonym)|uniprotkb:RNF106(gene name synonym)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 1(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 1(gene name synonym)|uniprotkb:Inverted CCAAT box-binding protein of 90 kDa(gene name synonym)|uniprotkb:Transcription factor ICBP90(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np95(gene name synonym)|uniprotkb:Nuclear protein 95(gene name synonym)|uniprotkb:RING finger protein 106(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF1(gene name synonym) psi-mi:dnm3a_human(display_long)|uniprotkb:DNMT3A(gene name)|psi-mi:DNMT3A(display_short)|uniprotkb:DNA methyltransferase HsaIIIA(gene name synonym)|uniprotkb:Cysteine methyltransferase DNMT3A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Meilinger et al. (2009) pubmed:19798101|imex:IM-13880|mint:MINT-7296296|doi:10.1038/embor.2009.201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7272023|mint:MINT-7296379|imex:IM-13880-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276979.1|refseq:NP_001276980.1|refseq:NP_001276981.1|refseq:NP_037414.3|refseq:NP_001041666.1|ensembl:ENSG00000276043(gene)|ensembl:ENST00000612630(transcript)|ensembl:ENST00000615884(transcript)|ensembl:ENST00000616255(transcript)|ensembl:ENST00000624301(transcript)|ensembl:ENST00000650932(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR000626(Ubiquitin)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|mint:Q96T88|rcsb pdb:2FAZ|rcsb pdb:2L3R|rcsb pdb:2LGG|rcsb pdb:2LGK|rcsb pdb:2LGL|rcsb pdb:2PB7|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3BI7|rcsb pdb:3CLZ|rcsb pdb:3DB3|rcsb pdb:3DB4|rcsb pdb:3DWH|rcsb pdb:3FL2|rcsb pdb:3SHB|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3SOX|rcsb pdb:3T6R|rcsb pdb:3ZVY|rcsb pdb:3ZVZ|rcsb pdb:4GY5|rcsb pdb:4QQD|rcsb pdb:5C6D|rcsb pdb:5IAY|rcsb pdb:5XPI|rcsb pdb:5YY9|rcsb pdb:5YYA|rcsb pdb:6B9M|rcsb pdb:6IIW|rcsb pdb:6VCS|rcsb pdb:6VED|rcsb pdb:6VYJ|rcsb pdb:6W92|reactome:R-HSA-5334118|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-7296383(identity) refseq:NP_001307821.1|refseq:NP_072046.2|refseq:NP_783328.1|refseq:NP_783329.1|refseq:XP_016859015.1|refseq:XP_016859016.1|refseq:XP_011530969.1|refseq:NP_001307822.1|refseq:NP_715640.2|refseq:XP_005264232.1|dip:DIP-38004N|refseq:XP_005264234.1|ensembl:ENSG00000119772(gene)|ensembl:ENST00000264709(transcript)|ensembl:ENST00000321117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010288"(response to lead ion)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0033189"(response to vitamin A)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030487|interpro:IPR040552|interpro:IPR044108|mint:Q9Y6K1|rcsb pdb:2QRV|rcsb pdb:3A1A|rcsb pdb:3A1B|rcsb pdb:3LLR|rcsb pdb:3SVM|rcsb pdb:4QBQ|rcsb pdb:4QBR|rcsb pdb:4QBS|rcsb pdb:4U7P|rcsb pdb:4U7T|rcsb pdb:5YX2|rcsb pdb:6BRR|rcsb pdb:6F57|rcsb pdb:6PA7|rcsb pdb:6W89|rcsb pdb:6W8B|rcsb pdb:6W8D|rcsb pdb:6W8J|reactome:R-HSA-212300|reactome:R-HSA-3214858|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|mint:MINT-7306357(identity) - - - figure legend:sf1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-embryonic_stem_ cells)|taxid:9606("Human-embryonic_stem_ cells (es cells)") - 2009/11/05 2014/10/16 rogid:AbWLjSoRl82HTcjZlG4DRavDdGc9606 rogid:rnq1Yv4tlQ1t9JXS3CfMmTlcPKE9606 intact-crc:8981421B1D226F40|rigid:lGKozt8rBVJaLmUcGwP3G6GJ+5U false green fluorescent protein tag:?-?(MINT-7296384) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q96T88 uniprotkb:Q9UBC3 intact:EBI-1548946|uniprotkb:Q8J022|uniprotkb:Q9H6S6|uniprotkb:Q9P115|uniprotkb:Q9P1U7|uniprotkb:A0JBR2|uniprotkb:A8K024|uniprotkb:B2RBA9|uniprotkb:Q2HIX7|ensembl:ENSP00000478348|ensembl:ENSP00000478601|ensembl:ENSP00000484739|ensembl:ENSP00000485604|ensembl:ENSP00000498698 intact:EBI-80125|uniprotkb:Q9UBD4|uniprotkb:Q9UJQ5|uniprotkb:Q9UKA6|uniprotkb:Q9UNE5|uniprotkb:Q9Y5R9|uniprotkb:Q9Y5S0|intact:EBI-28970262|ensembl:ENSP00000328547|uniprotkb:A2A2E2|uniprotkb:E1P5M6|uniprotkb:E1P5M7|uniprotkb:B4DSM8|uniprotkb:B4DSU1|uniprotkb:E7EN63|uniprotkb:E9PBF2 psi-mi:uhrf1_human(display_long)|uniprotkb:UHRF1(gene name)|psi-mi:UHRF1(display_short)|uniprotkb:ICBP90(gene name synonym)|uniprotkb:NP95(gene name synonym)|uniprotkb:RNF106(gene name synonym)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 1(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 1(gene name synonym)|uniprotkb:Inverted CCAAT box-binding protein of 90 kDa(gene name synonym)|uniprotkb:Transcription factor ICBP90(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np95(gene name synonym)|uniprotkb:Nuclear protein 95(gene name synonym)|uniprotkb:RING finger protein 106(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF1(gene name synonym) psi-mi:dnm3b_human(display_long)|uniprotkb:DNMT3B(gene name)|psi-mi:DNMT3B(display_short)|uniprotkb:DNA methyltransferase HsaIIIB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Meilinger et al. (2009) pubmed:19798101|imex:IM-13880|mint:MINT-7296296|doi:10.1038/embor.2009.201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7272023|mint:MINT-7296379|imex:IM-13880-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276979.1|refseq:NP_001276980.1|refseq:NP_001276981.1|refseq:NP_037414.3|refseq:NP_001041666.1|ensembl:ENSG00000276043(gene)|ensembl:ENST00000612630(transcript)|ensembl:ENST00000615884(transcript)|ensembl:ENST00000616255(transcript)|ensembl:ENST00000624301(transcript)|ensembl:ENST00000650932(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR000626(Ubiquitin)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|mint:Q96T88|rcsb pdb:2FAZ|rcsb pdb:2L3R|rcsb pdb:2LGG|rcsb pdb:2LGK|rcsb pdb:2LGL|rcsb pdb:2PB7|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3BI7|rcsb pdb:3CLZ|rcsb pdb:3DB3|rcsb pdb:3DB4|rcsb pdb:3DWH|rcsb pdb:3FL2|rcsb pdb:3SHB|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3SOX|rcsb pdb:3T6R|rcsb pdb:3ZVY|rcsb pdb:3ZVZ|rcsb pdb:4GY5|rcsb pdb:4QQD|rcsb pdb:5C6D|rcsb pdb:5IAY|rcsb pdb:5XPI|rcsb pdb:5YY9|rcsb pdb:5YYA|rcsb pdb:6B9M|rcsb pdb:6IIW|rcsb pdb:6VCS|rcsb pdb:6VED|rcsb pdb:6VYJ|rcsb pdb:6W92|reactome:R-HSA-5334118|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-7296383(identity) ensembl:ENSG00000088305(gene)|ensembl:ENST00000328111(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0009008"(DNA-methyltransferase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014823"(response to activity)|go:"GO:0031000"(response to caffeine)|go:"GO:0032355"(response to estradiol)|go:"GO:0033189"(response to vitamin A)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030488|interpro:IPR040552|mint:Q9UBC3|rcsb pdb:3FLG|rcsb pdb:3QKJ|rcsb pdb:5CIU|rcsb pdb:5NR3|rcsb pdb:5NRR|rcsb pdb:5NRV|rcsb pdb:5NV0|rcsb pdb:5NV2|rcsb pdb:5NV7|rcsb pdb:5NVO|rcsb pdb:6KDA|rcsb pdb:6KDB|rcsb pdb:6KDL|rcsb pdb:6KDP|rcsb pdb:6KDT|rcsb pdb:6PA7|rcsb pdb:6R3E|rcsb pdb:6U8P|rcsb pdb:6U8V|rcsb pdb:6U8W|rcsb pdb:6U8X|rcsb pdb:5NRS|rcsb pdb:6U90|rcsb pdb:6U91|reactome:R-HSA-212300|reactome:R-HSA-427413|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|ensembl:ENST00000353855|ensembl:ENSP00000313397|ensembl:ENST00000443239|ensembl:ENSP00000403169|ensembl:ENST00000456297|ensembl:ENSP00000412305|ensembl:ENST00000201963|ensembl:ENSP00000201963|ensembl:ENSP00000328547|ensembl:ENST00000348286|ensembl:ENSP00000337764|refseq:NP_001193984.1|refseq:NP_001193985.1|refseq:NP_008823.1|refseq:NP_787044.1|refseq:NP_787045.1|refseq:NP_787046.1|dip:DIP-30000N|mint:MINT-7296381(identity) - - - figure legend:sf1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-embryonic_stem_ cells)|taxid:9606("Human-embryonic_stem_ cells (es cells)") - 2009/11/05 2014/10/16 rogid:AbWLjSoRl82HTcjZlG4DRavDdGc9606 rogid:xxbu/yvuQ1KnhVE/FdTh9CyA6jw9606 intact-crc:8981421B1D226F40|rigid:lGKozt8rBVJaLmUcGwP3G6GJ+5U false green fluorescent protein tag:?-?(MINT-7296384) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y6K1 uniprotkb:Q96T88 intact:EBI-923653|uniprotkb:Q8WXU9|uniprotkb:Q86XF5|uniprotkb:Q8IZV0|uniprotkb:Q86TE8|uniprotkb:E9PEB8|ensembl:ENSP00000264709|ensembl:ENSP00000324375 intact:EBI-1548946|uniprotkb:Q8J022|uniprotkb:Q9H6S6|uniprotkb:Q9P115|uniprotkb:Q9P1U7|uniprotkb:A0JBR2|uniprotkb:A8K024|uniprotkb:B2RBA9|uniprotkb:Q2HIX7|ensembl:ENSP00000478348|ensembl:ENSP00000478601|ensembl:ENSP00000484739|ensembl:ENSP00000485604|ensembl:ENSP00000498698 psi-mi:dnm3a_human(display_long)|uniprotkb:DNMT3A(gene name)|psi-mi:DNMT3A(display_short)|uniprotkb:DNA methyltransferase HsaIIIA(gene name synonym)|uniprotkb:Cysteine methyltransferase DNMT3A(gene name synonym) psi-mi:uhrf1_human(display_long)|uniprotkb:UHRF1(gene name)|psi-mi:UHRF1(display_short)|uniprotkb:ICBP90(gene name synonym)|uniprotkb:NP95(gene name synonym)|uniprotkb:RNF106(gene name synonym)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 1(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 1(gene name synonym)|uniprotkb:Inverted CCAAT box-binding protein of 90 kDa(gene name synonym)|uniprotkb:Transcription factor ICBP90(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np95(gene name synonym)|uniprotkb:Nuclear protein 95(gene name synonym)|uniprotkb:RING finger protein 106(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Meilinger et al. (2009) pubmed:19798101|imex:IM-13880|mint:MINT-7296296|doi:10.1038/embor.2009.201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7272059|mint:MINT-7296402|imex:IM-13880-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001307821.1|refseq:NP_072046.2|refseq:NP_783328.1|refseq:NP_783329.1|refseq:XP_016859015.1|refseq:XP_016859016.1|refseq:XP_011530969.1|refseq:NP_001307822.1|refseq:NP_715640.2|refseq:XP_005264232.1|dip:DIP-38004N|refseq:XP_005264234.1|ensembl:ENSG00000119772(gene)|ensembl:ENST00000264709(transcript)|ensembl:ENST00000321117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010288"(response to lead ion)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0033189"(response to vitamin A)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030487|interpro:IPR040552|interpro:IPR044108|mint:Q9Y6K1|rcsb pdb:2QRV|rcsb pdb:3A1A|rcsb pdb:3A1B|rcsb pdb:3LLR|rcsb pdb:3SVM|rcsb pdb:4QBQ|rcsb pdb:4QBR|rcsb pdb:4QBS|rcsb pdb:4U7P|rcsb pdb:4U7T|rcsb pdb:5YX2|rcsb pdb:6BRR|rcsb pdb:6F57|rcsb pdb:6PA7|rcsb pdb:6W89|rcsb pdb:6W8B|rcsb pdb:6W8D|rcsb pdb:6W8J|reactome:R-HSA-212300|reactome:R-HSA-3214858|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|mint:MINT-7296404(identity) refseq:NP_001276979.1|refseq:NP_001276980.1|refseq:NP_001276981.1|refseq:NP_037414.3|refseq:NP_001041666.1|ensembl:ENSG00000276043(gene)|ensembl:ENST00000612630(transcript)|ensembl:ENST00000615884(transcript)|ensembl:ENST00000616255(transcript)|ensembl:ENST00000624301(transcript)|ensembl:ENST00000650932(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR000626(Ubiquitin)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|mint:Q96T88|rcsb pdb:2FAZ|rcsb pdb:2L3R|rcsb pdb:2LGG|rcsb pdb:2LGK|rcsb pdb:2LGL|rcsb pdb:2PB7|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3BI7|rcsb pdb:3CLZ|rcsb pdb:3DB3|rcsb pdb:3DB4|rcsb pdb:3DWH|rcsb pdb:3FL2|rcsb pdb:3SHB|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3SOX|rcsb pdb:3T6R|rcsb pdb:3ZVY|rcsb pdb:3ZVZ|rcsb pdb:4GY5|rcsb pdb:4QQD|rcsb pdb:5C6D|rcsb pdb:5IAY|rcsb pdb:5XPI|rcsb pdb:5YY9|rcsb pdb:5YYA|rcsb pdb:6B9M|rcsb pdb:6IIW|rcsb pdb:6VCS|rcsb pdb:6VED|rcsb pdb:6VYJ|rcsb pdb:6W92|reactome:R-HSA-5334118|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-7296406(identity) - - - comment:homomint|comment:mint|figure legend:sf1b sf1d|comment:this experiment has been performed both in ESC dmt1 -/- and ESC DKO cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-embryonic_stem_ cells)|taxid:9606("Human-embryonic_stem_ cells (es cells)") - 2009/11/05 2014/10/16 rogid:rnq1Yv4tlQ1t9JXS3CfMmTlcPKE9606 rogid:AbWLjSoRl82HTcjZlG4DRavDdGc9606 intact-crc:2CE4B4F55B711838|rigid:mebVOSa1jY1DcK+vvFibgMvyUSs false green fluorescent protein tag:?-?(MINT-7296417) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96T88 uniprotkb:Q9Y6K1 intact:EBI-1548946|uniprotkb:Q8J022|uniprotkb:Q9H6S6|uniprotkb:Q9P115|uniprotkb:Q9P1U7|uniprotkb:A0JBR2|uniprotkb:A8K024|uniprotkb:B2RBA9|uniprotkb:Q2HIX7|ensembl:ENSP00000478348|ensembl:ENSP00000478601|ensembl:ENSP00000484739|ensembl:ENSP00000485604|ensembl:ENSP00000498698 intact:EBI-923653|uniprotkb:Q8WXU9|uniprotkb:Q86XF5|uniprotkb:Q8IZV0|uniprotkb:Q86TE8|uniprotkb:E9PEB8|ensembl:ENSP00000264709|ensembl:ENSP00000324375 psi-mi:uhrf1_human(display_long)|uniprotkb:UHRF1(gene name)|psi-mi:UHRF1(display_short)|uniprotkb:ICBP90(gene name synonym)|uniprotkb:NP95(gene name synonym)|uniprotkb:RNF106(gene name synonym)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 1(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 1(gene name synonym)|uniprotkb:Inverted CCAAT box-binding protein of 90 kDa(gene name synonym)|uniprotkb:Transcription factor ICBP90(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np95(gene name synonym)|uniprotkb:Nuclear protein 95(gene name synonym)|uniprotkb:RING finger protein 106(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF1(gene name synonym) psi-mi:dnm3a_human(display_long)|uniprotkb:DNMT3A(gene name)|psi-mi:DNMT3A(display_short)|uniprotkb:DNA methyltransferase HsaIIIA(gene name synonym)|uniprotkb:Cysteine methyltransferase DNMT3A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Meilinger et al. (2009) pubmed:19798101|imex:IM-13880|mint:MINT-7296296|doi:10.1038/embor.2009.201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7272041|mint:MINT-7296389|imex:IM-13880-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276979.1|refseq:NP_001276980.1|refseq:NP_001276981.1|refseq:NP_037414.3|refseq:NP_001041666.1|ensembl:ENSG00000276043(gene)|ensembl:ENST00000612630(transcript)|ensembl:ENST00000615884(transcript)|ensembl:ENST00000616255(transcript)|ensembl:ENST00000624301(transcript)|ensembl:ENST00000650932(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR000626(Ubiquitin)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|mint:Q96T88|rcsb pdb:2FAZ|rcsb pdb:2L3R|rcsb pdb:2LGG|rcsb pdb:2LGK|rcsb pdb:2LGL|rcsb pdb:2PB7|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3BI7|rcsb pdb:3CLZ|rcsb pdb:3DB3|rcsb pdb:3DB4|rcsb pdb:3DWH|rcsb pdb:3FL2|rcsb pdb:3SHB|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3SOX|rcsb pdb:3T6R|rcsb pdb:3ZVY|rcsb pdb:3ZVZ|rcsb pdb:4GY5|rcsb pdb:4QQD|rcsb pdb:5C6D|rcsb pdb:5IAY|rcsb pdb:5XPI|rcsb pdb:5YY9|rcsb pdb:5YYA|rcsb pdb:6B9M|rcsb pdb:6IIW|rcsb pdb:6VCS|rcsb pdb:6VED|rcsb pdb:6VYJ|rcsb pdb:6W92|reactome:R-HSA-5334118|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-7296393(identity) refseq:NP_001307821.1|refseq:NP_072046.2|refseq:NP_783328.1|refseq:NP_783329.1|refseq:XP_016859015.1|refseq:XP_016859016.1|refseq:XP_011530969.1|refseq:NP_001307822.1|refseq:NP_715640.2|refseq:XP_005264232.1|dip:DIP-38004N|refseq:XP_005264234.1|ensembl:ENSG00000119772(gene)|ensembl:ENST00000264709(transcript)|ensembl:ENST00000321117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010288"(response to lead ion)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0033189"(response to vitamin A)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030487|interpro:IPR040552|interpro:IPR044108|mint:Q9Y6K1|rcsb pdb:2QRV|rcsb pdb:3A1A|rcsb pdb:3A1B|rcsb pdb:3LLR|rcsb pdb:3SVM|rcsb pdb:4QBQ|rcsb pdb:4QBR|rcsb pdb:4QBS|rcsb pdb:4U7P|rcsb pdb:4U7T|rcsb pdb:5YX2|rcsb pdb:6BRR|rcsb pdb:6F57|rcsb pdb:6PA7|rcsb pdb:6W89|rcsb pdb:6W8B|rcsb pdb:6W8D|rcsb pdb:6W8J|reactome:R-HSA-212300|reactome:R-HSA-3214858|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|mint:MINT-7306362(identity) - - - figure legend:sf1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-embryonic_stem_ cells)|taxid:9606("Human-embryonic_stem_ cells (es cells)") - 2009/11/05 2014/10/16 rogid:AbWLjSoRl82HTcjZlG4DRavDdGc9606 rogid:rnq1Yv4tlQ1t9JXS3CfMmTlcPKE9606 intact-crc:3CE85CE006DE40CB|rigid:2Jfp18N3MI6O4dhJYbIc4u/MsE4 false green fluorescent protein tag:?-?(MINT-7296394) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q96T88 uniprotkb:P26358 intact:EBI-1548946|uniprotkb:Q8J022|uniprotkb:Q9H6S6|uniprotkb:Q9P115|uniprotkb:Q9P1U7|uniprotkb:A0JBR2|uniprotkb:A8K024|uniprotkb:B2RBA9|uniprotkb:Q2HIX7|ensembl:ENSP00000478348|ensembl:ENSP00000478601|ensembl:ENSP00000484739|ensembl:ENSP00000485604|ensembl:ENSP00000498698 intact:EBI-719459|uniprotkb:Q9UHG5|uniprotkb:Q9ULA2|uniprotkb:Q9UMZ6|uniprotkb:A0AV63|intact:EBI-28971395|ensembl:ENSP00000345739|uniprotkb:B7ZLW6 psi-mi:uhrf1_human(display_long)|uniprotkb:UHRF1(gene name)|psi-mi:UHRF1(display_short)|uniprotkb:ICBP90(gene name synonym)|uniprotkb:NP95(gene name synonym)|uniprotkb:RNF106(gene name synonym)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 1(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 1(gene name synonym)|uniprotkb:Inverted CCAAT box-binding protein of 90 kDa(gene name synonym)|uniprotkb:Transcription factor ICBP90(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np95(gene name synonym)|uniprotkb:Nuclear protein 95(gene name synonym)|uniprotkb:RING finger protein 106(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF1(gene name synonym) psi-mi:dnmt1_human(display_long)|uniprotkb:CXXC9(gene name synonym)|uniprotkb:MCMT(gene name synonym)|uniprotkb:DNA methyltransferase HsaI(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 9(gene name synonym)|uniprotkb:DNMT1(gene name)|psi-mi:DNMT1(display_short)|uniprotkb:AIM(gene name synonym)|uniprotkb:DNMT(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Meilinger et al. (2009) pubmed:19798101|imex:IM-13880|mint:MINT-7296296|doi:10.1038/embor.2009.201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7272041|mint:MINT-7296389|imex:IM-13880-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276979.1|refseq:NP_001276980.1|refseq:NP_001276981.1|refseq:NP_037414.3|refseq:NP_001041666.1|ensembl:ENSG00000276043(gene)|ensembl:ENST00000612630(transcript)|ensembl:ENST00000615884(transcript)|ensembl:ENST00000616255(transcript)|ensembl:ENST00000624301(transcript)|ensembl:ENST00000650932(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR000626(Ubiquitin)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|mint:Q96T88|rcsb pdb:2FAZ|rcsb pdb:2L3R|rcsb pdb:2LGG|rcsb pdb:2LGK|rcsb pdb:2LGL|rcsb pdb:2PB7|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3BI7|rcsb pdb:3CLZ|rcsb pdb:3DB3|rcsb pdb:3DB4|rcsb pdb:3DWH|rcsb pdb:3FL2|rcsb pdb:3SHB|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3SOX|rcsb pdb:3T6R|rcsb pdb:3ZVY|rcsb pdb:3ZVZ|rcsb pdb:4GY5|rcsb pdb:4QQD|rcsb pdb:5C6D|rcsb pdb:5IAY|rcsb pdb:5XPI|rcsb pdb:5YY9|rcsb pdb:5YYA|rcsb pdb:6B9M|rcsb pdb:6IIW|rcsb pdb:6VCS|rcsb pdb:6VED|rcsb pdb:6VYJ|rcsb pdb:6W92|reactome:R-HSA-5334118|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-7296393(identity) ensembl:ENSP00000345739|ensembl:ENST00000359526|ensembl:ENSP00000352516|refseq:NP_001124295.1|refseq:NP_001370.1|ensembl:ENSG00000130816(gene)|ensembl:ENST00000340748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008270"(zinc ion binding)|reactome:R-HSA-427413|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|refseq:NP_001305659.1|refseq:NP_001305660.1|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009008"(DNA-methyltransferase activity)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905931"(negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR010506(DMAP1-binding)|interpro:IPR017198("DNA (cytosine-5)-methyltransferase 1")|interpro:IPR018117|interpro:IPR022702|interpro:IPR029063|interpro:IPR031303|interpro:IPR043151|mint:P26358|rcsb pdb:3EPZ|rcsb pdb:3PTA|rcsb pdb:3SWR|rcsb pdb:4WXX|rcsb pdb:4YOC|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5WVO|rcsb pdb:5YDR|rcsb pdb:6K3A|reactome:R-HSA-212300|dip:DIP-39693N|mint:MINT-7296391(identity) - - - figure legend:sf1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-embryonic_stem_ cells)|taxid:9606("Human-embryonic_stem_ cells (es cells)") - 2009/11/05 2014/10/16 rogid:AbWLjSoRl82HTcjZlG4DRavDdGc9606 rogid:qae3zQwGP5R/+WCWoeahDKZ/9Jg9606 intact-crc:3CE85CE006DE40CB|rigid:2Jfp18N3MI6O4dhJYbIc4u/MsE4 false green fluorescent protein tag:?-?(MINT-7296394) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UBC3 uniprotkb:Q96T88 intact:EBI-80125|uniprotkb:Q9UBD4|uniprotkb:Q9UJQ5|uniprotkb:Q9UKA6|uniprotkb:Q9UNE5|uniprotkb:Q9Y5R9|uniprotkb:Q9Y5S0|intact:EBI-28970262|ensembl:ENSP00000328547|uniprotkb:A2A2E2|uniprotkb:E1P5M6|uniprotkb:E1P5M7|uniprotkb:B4DSM8|uniprotkb:B4DSU1|uniprotkb:E7EN63|uniprotkb:E9PBF2 intact:EBI-1548946|uniprotkb:Q8J022|uniprotkb:Q9H6S6|uniprotkb:Q9P115|uniprotkb:Q9P1U7|uniprotkb:A0JBR2|uniprotkb:A8K024|uniprotkb:B2RBA9|uniprotkb:Q2HIX7|ensembl:ENSP00000478348|ensembl:ENSP00000478601|ensembl:ENSP00000484739|ensembl:ENSP00000485604|ensembl:ENSP00000498698 psi-mi:dnm3b_human(display_long)|uniprotkb:DNMT3B(gene name)|psi-mi:DNMT3B(display_short)|uniprotkb:DNA methyltransferase HsaIIIB(gene name synonym) psi-mi:uhrf1_human(display_long)|uniprotkb:UHRF1(gene name)|psi-mi:UHRF1(display_short)|uniprotkb:ICBP90(gene name synonym)|uniprotkb:NP95(gene name synonym)|uniprotkb:RNF106(gene name synonym)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 1(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 1(gene name synonym)|uniprotkb:Inverted CCAAT box-binding protein of 90 kDa(gene name synonym)|uniprotkb:Transcription factor ICBP90(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np95(gene name synonym)|uniprotkb:Nuclear protein 95(gene name synonym)|uniprotkb:RING finger protein 106(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Meilinger et al. (2009) pubmed:19798101|imex:IM-13880|mint:MINT-7296296|doi:10.1038/embor.2009.201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7272075|mint:MINT-7296421|imex:IM-13880-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000088305(gene)|ensembl:ENST00000328111(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0009008"(DNA-methyltransferase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014823"(response to activity)|go:"GO:0031000"(response to caffeine)|go:"GO:0032355"(response to estradiol)|go:"GO:0033189"(response to vitamin A)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030488|interpro:IPR040552|mint:Q9UBC3|rcsb pdb:3FLG|rcsb pdb:3QKJ|rcsb pdb:5CIU|rcsb pdb:5NR3|rcsb pdb:5NRR|rcsb pdb:5NRV|rcsb pdb:5NV0|rcsb pdb:5NV2|rcsb pdb:5NV7|rcsb pdb:5NVO|rcsb pdb:6KDA|rcsb pdb:6KDB|rcsb pdb:6KDL|rcsb pdb:6KDP|rcsb pdb:6KDT|rcsb pdb:6PA7|rcsb pdb:6R3E|rcsb pdb:6U8P|rcsb pdb:6U8V|rcsb pdb:6U8W|rcsb pdb:6U8X|rcsb pdb:5NRS|rcsb pdb:6U90|rcsb pdb:6U91|reactome:R-HSA-212300|reactome:R-HSA-427413|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|ensembl:ENST00000353855|ensembl:ENSP00000313397|ensembl:ENST00000443239|ensembl:ENSP00000403169|ensembl:ENST00000456297|ensembl:ENSP00000412305|ensembl:ENST00000201963|ensembl:ENSP00000201963|ensembl:ENSP00000328547|ensembl:ENST00000348286|ensembl:ENSP00000337764|refseq:NP_001193984.1|refseq:NP_001193985.1|refseq:NP_008823.1|refseq:NP_787044.1|refseq:NP_787045.1|refseq:NP_787046.1|dip:DIP-30000N|mint:MINT-7296425(identity) refseq:NP_001276979.1|refseq:NP_001276980.1|refseq:NP_001276981.1|refseq:NP_037414.3|refseq:NP_001041666.1|ensembl:ENSG00000276043(gene)|ensembl:ENST00000612630(transcript)|ensembl:ENST00000615884(transcript)|ensembl:ENST00000616255(transcript)|ensembl:ENST00000624301(transcript)|ensembl:ENST00000650932(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR000626(Ubiquitin)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|mint:Q96T88|rcsb pdb:2FAZ|rcsb pdb:2L3R|rcsb pdb:2LGG|rcsb pdb:2LGK|rcsb pdb:2LGL|rcsb pdb:2PB7|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3BI7|rcsb pdb:3CLZ|rcsb pdb:3DB3|rcsb pdb:3DB4|rcsb pdb:3DWH|rcsb pdb:3FL2|rcsb pdb:3SHB|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3SOX|rcsb pdb:3T6R|rcsb pdb:3ZVY|rcsb pdb:3ZVZ|rcsb pdb:4GY5|rcsb pdb:4QQD|rcsb pdb:5C6D|rcsb pdb:5IAY|rcsb pdb:5XPI|rcsb pdb:5YY9|rcsb pdb:5YYA|rcsb pdb:6B9M|rcsb pdb:6IIW|rcsb pdb:6VCS|rcsb pdb:6VED|rcsb pdb:6VYJ|rcsb pdb:6W92|reactome:R-HSA-5334118|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-7296423(identity) - - - comment:homomint|comment:mint|figure legend:sf1b sf1d|comment:this experiment has been performed both in ESC dmt1 -/- and ESC DKO cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-embryonic_stem_ cells)|taxid:9606("Human-embryonic_stem_ cells (es cells)") - 2009/11/05 2014/10/16 rogid:xxbu/yvuQ1KnhVE/FdTh9CyA6jw9606 rogid:AbWLjSoRl82HTcjZlG4DRavDdGc9606 intact-crc:30C2DC97EE27DB62|rigid:CH/Jr54jUjCu+ccmnxjDtPfFrI4 false green fluorescent protein tag:?-?(MINT-7296426) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y6K1 uniprotkb:Q96T88 intact:EBI-923653|uniprotkb:Q8WXU9|uniprotkb:Q86XF5|uniprotkb:Q8IZV0|uniprotkb:Q86TE8|uniprotkb:E9PEB8|ensembl:ENSP00000264709|ensembl:ENSP00000324375 intact:EBI-1548946|uniprotkb:Q8J022|uniprotkb:Q9H6S6|uniprotkb:Q9P115|uniprotkb:Q9P1U7|uniprotkb:A0JBR2|uniprotkb:A8K024|uniprotkb:B2RBA9|uniprotkb:Q2HIX7|ensembl:ENSP00000478348|ensembl:ENSP00000478601|ensembl:ENSP00000484739|ensembl:ENSP00000485604|ensembl:ENSP00000498698 psi-mi:dnm3a_human(display_long)|uniprotkb:DNMT3A(gene name)|psi-mi:DNMT3A(display_short)|uniprotkb:DNA methyltransferase HsaIIIA(gene name synonym)|uniprotkb:Cysteine methyltransferase DNMT3A(gene name synonym) psi-mi:uhrf1_human(display_long)|uniprotkb:UHRF1(gene name)|psi-mi:UHRF1(display_short)|uniprotkb:ICBP90(gene name synonym)|uniprotkb:NP95(gene name synonym)|uniprotkb:RNF106(gene name synonym)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 1(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 1(gene name synonym)|uniprotkb:Inverted CCAAT box-binding protein of 90 kDa(gene name synonym)|uniprotkb:Transcription factor ICBP90(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np95(gene name synonym)|uniprotkb:Nuclear protein 95(gene name synonym)|uniprotkb:RING finger protein 106(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF1(gene name synonym) psi-mi:"MI:0051"(fluorescence technology) Meilinger et al. (2009) pubmed:19798101|imex:IM-13880|mint:MINT-7296296|doi:10.1038/embor.2009.201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7272100|mint:MINT-7296491|imex:IM-13880-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001307821.1|refseq:NP_072046.2|refseq:NP_783328.1|refseq:NP_783329.1|refseq:XP_016859015.1|refseq:XP_016859016.1|refseq:XP_011530969.1|refseq:NP_001307822.1|refseq:NP_715640.2|refseq:XP_005264232.1|dip:DIP-38004N|refseq:XP_005264234.1|ensembl:ENSG00000119772(gene)|ensembl:ENST00000264709(transcript)|ensembl:ENST00000321117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010288"(response to lead ion)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0033189"(response to vitamin A)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030487|interpro:IPR040552|interpro:IPR044108|mint:Q9Y6K1|rcsb pdb:2QRV|rcsb pdb:3A1A|rcsb pdb:3A1B|rcsb pdb:3LLR|rcsb pdb:3SVM|rcsb pdb:4QBQ|rcsb pdb:4QBR|rcsb pdb:4QBS|rcsb pdb:4U7P|rcsb pdb:4U7T|rcsb pdb:5YX2|rcsb pdb:6BRR|rcsb pdb:6F57|rcsb pdb:6PA7|rcsb pdb:6W89|rcsb pdb:6W8B|rcsb pdb:6W8D|rcsb pdb:6W8J|reactome:R-HSA-212300|reactome:R-HSA-3214858|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|mint:MINT-7296499(identity) refseq:NP_001276979.1|refseq:NP_001276980.1|refseq:NP_001276981.1|refseq:NP_037414.3|refseq:NP_001041666.1|ensembl:ENSG00000276043(gene)|ensembl:ENST00000612630(transcript)|ensembl:ENST00000615884(transcript)|ensembl:ENST00000616255(transcript)|ensembl:ENST00000624301(transcript)|ensembl:ENST00000650932(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR000626(Ubiquitin)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|mint:Q96T88|rcsb pdb:2FAZ|rcsb pdb:2L3R|rcsb pdb:2LGG|rcsb pdb:2LGK|rcsb pdb:2LGL|rcsb pdb:2PB7|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3BI7|rcsb pdb:3CLZ|rcsb pdb:3DB3|rcsb pdb:3DB4|rcsb pdb:3DWH|rcsb pdb:3FL2|rcsb pdb:3SHB|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3SOX|rcsb pdb:3T6R|rcsb pdb:3ZVY|rcsb pdb:3ZVZ|rcsb pdb:4GY5|rcsb pdb:4QQD|rcsb pdb:5C6D|rcsb pdb:5IAY|rcsb pdb:5XPI|rcsb pdb:5YY9|rcsb pdb:5YYA|rcsb pdb:6B9M|rcsb pdb:6IIW|rcsb pdb:6VCS|rcsb pdb:6VED|rcsb pdb:6VYJ|rcsb pdb:6W92|reactome:R-HSA-5334118|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-7296493(identity) - - - figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:36483(crisp-kidney)|taxid:36483(Cricetidae sp.) - 2009/11/05 2014/10/16 rogid:rnq1Yv4tlQ1t9JXS3CfMmTlcPKE9606 rogid:AbWLjSoRl82HTcjZlG4DRavDdGc9606 intact-crc:48CB560A65CCBB7A|rigid:mebVOSa1jY1DcK+vvFibgMvyUSs false green fluorescent protein tag:?-?(MINT-7296502)|binding-associated region:1-630(MINT-7296500) tag:?-?(MINT-7296496) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UBC3 uniprotkb:Q96T88 intact:EBI-80125|uniprotkb:Q9UBD4|uniprotkb:Q9UJQ5|uniprotkb:Q9UKA6|uniprotkb:Q9UNE5|uniprotkb:Q9Y5R9|uniprotkb:Q9Y5S0|intact:EBI-28970262|ensembl:ENSP00000328547|uniprotkb:A2A2E2|uniprotkb:E1P5M6|uniprotkb:E1P5M7|uniprotkb:B4DSM8|uniprotkb:B4DSU1|uniprotkb:E7EN63|uniprotkb:E9PBF2 intact:EBI-1548946|uniprotkb:Q8J022|uniprotkb:Q9H6S6|uniprotkb:Q9P115|uniprotkb:Q9P1U7|uniprotkb:A0JBR2|uniprotkb:A8K024|uniprotkb:B2RBA9|uniprotkb:Q2HIX7|ensembl:ENSP00000478348|ensembl:ENSP00000478601|ensembl:ENSP00000484739|ensembl:ENSP00000485604|ensembl:ENSP00000498698 psi-mi:dnm3b_human(display_long)|uniprotkb:DNMT3B(gene name)|psi-mi:DNMT3B(display_short)|uniprotkb:DNA methyltransferase HsaIIIB(gene name synonym) psi-mi:uhrf1_human(display_long)|uniprotkb:UHRF1(gene name)|psi-mi:UHRF1(display_short)|uniprotkb:ICBP90(gene name synonym)|uniprotkb:NP95(gene name synonym)|uniprotkb:RNF106(gene name synonym)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 1(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 1(gene name synonym)|uniprotkb:Inverted CCAAT box-binding protein of 90 kDa(gene name synonym)|uniprotkb:Transcription factor ICBP90(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np95(gene name synonym)|uniprotkb:Nuclear protein 95(gene name synonym)|uniprotkb:RING finger protein 106(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF1(gene name synonym) psi-mi:"MI:0051"(fluorescence technology) Meilinger et al. (2009) pubmed:19798101|imex:IM-13880|mint:MINT-7296296|doi:10.1038/embor.2009.201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7272121|mint:MINT-7296510|imex:IM-13880-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000088305(gene)|ensembl:ENST00000328111(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0009008"(DNA-methyltransferase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014823"(response to activity)|go:"GO:0031000"(response to caffeine)|go:"GO:0032355"(response to estradiol)|go:"GO:0033189"(response to vitamin A)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030488|interpro:IPR040552|mint:Q9UBC3|rcsb pdb:3FLG|rcsb pdb:3QKJ|rcsb pdb:5CIU|rcsb pdb:5NR3|rcsb pdb:5NRR|rcsb pdb:5NRV|rcsb pdb:5NV0|rcsb pdb:5NV2|rcsb pdb:5NV7|rcsb pdb:5NVO|rcsb pdb:6KDA|rcsb pdb:6KDB|rcsb pdb:6KDL|rcsb pdb:6KDP|rcsb pdb:6KDT|rcsb pdb:6PA7|rcsb pdb:6R3E|rcsb pdb:6U8P|rcsb pdb:6U8V|rcsb pdb:6U8W|rcsb pdb:6U8X|rcsb pdb:5NRS|rcsb pdb:6U90|rcsb pdb:6U91|reactome:R-HSA-212300|reactome:R-HSA-427413|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|ensembl:ENST00000353855|ensembl:ENSP00000313397|ensembl:ENST00000443239|ensembl:ENSP00000403169|ensembl:ENST00000456297|ensembl:ENSP00000412305|ensembl:ENST00000201963|ensembl:ENSP00000201963|ensembl:ENSP00000328547|ensembl:ENST00000348286|ensembl:ENSP00000337764|refseq:NP_001193984.1|refseq:NP_001193985.1|refseq:NP_008823.1|refseq:NP_787044.1|refseq:NP_787045.1|refseq:NP_787046.1|dip:DIP-30000N|mint:MINT-7296512(identity) refseq:NP_001276979.1|refseq:NP_001276980.1|refseq:NP_001276981.1|refseq:NP_037414.3|refseq:NP_001041666.1|ensembl:ENSG00000276043(gene)|ensembl:ENST00000612630(transcript)|ensembl:ENST00000615884(transcript)|ensembl:ENST00000616255(transcript)|ensembl:ENST00000624301(transcript)|ensembl:ENST00000650932(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR000626(Ubiquitin)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|mint:Q96T88|rcsb pdb:2FAZ|rcsb pdb:2L3R|rcsb pdb:2LGG|rcsb pdb:2LGK|rcsb pdb:2LGL|rcsb pdb:2PB7|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3BI7|rcsb pdb:3CLZ|rcsb pdb:3DB3|rcsb pdb:3DB4|rcsb pdb:3DWH|rcsb pdb:3FL2|rcsb pdb:3SHB|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3SOX|rcsb pdb:3T6R|rcsb pdb:3ZVY|rcsb pdb:3ZVZ|rcsb pdb:4GY5|rcsb pdb:4QQD|rcsb pdb:5C6D|rcsb pdb:5IAY|rcsb pdb:5XPI|rcsb pdb:5YY9|rcsb pdb:5YYA|rcsb pdb:6B9M|rcsb pdb:6IIW|rcsb pdb:6VCS|rcsb pdb:6VED|rcsb pdb:6VYJ|rcsb pdb:6W92|reactome:R-HSA-5334118|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-7296518(identity) - - - figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:36483(crisp-kidney)|taxid:36483(Cricetidae sp.) - 2009/11/05 2014/10/16 rogid:xxbu/yvuQ1KnhVE/FdTh9CyA6jw9606 rogid:AbWLjSoRl82HTcjZlG4DRavDdGc9606 intact-crc:DF0C7034DA8A1D0F|rigid:CH/Jr54jUjCu+ccmnxjDtPfFrI4 false binding-associated region:1-581(MINT-7296515)|green fluorescent protein tag:?-?(MINT-7296513) tag:?-?(MINT-7296519) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UBC3 uniprotkb:Q96T88 intact:EBI-80125|uniprotkb:Q9UBD4|uniprotkb:Q9UJQ5|uniprotkb:Q9UKA6|uniprotkb:Q9UNE5|uniprotkb:Q9Y5R9|uniprotkb:Q9Y5S0|intact:EBI-28970262|ensembl:ENSP00000328547|uniprotkb:A2A2E2|uniprotkb:E1P5M6|uniprotkb:E1P5M7|uniprotkb:B4DSM8|uniprotkb:B4DSU1|uniprotkb:E7EN63|uniprotkb:E9PBF2 intact:EBI-1548946|uniprotkb:Q8J022|uniprotkb:Q9H6S6|uniprotkb:Q9P115|uniprotkb:Q9P1U7|uniprotkb:A0JBR2|uniprotkb:A8K024|uniprotkb:B2RBA9|uniprotkb:Q2HIX7|ensembl:ENSP00000478348|ensembl:ENSP00000478601|ensembl:ENSP00000484739|ensembl:ENSP00000485604|ensembl:ENSP00000498698 psi-mi:dnm3b_human(display_long)|uniprotkb:DNMT3B(gene name)|psi-mi:DNMT3B(display_short)|uniprotkb:DNA methyltransferase HsaIIIB(gene name synonym) psi-mi:uhrf1_human(display_long)|uniprotkb:UHRF1(gene name)|psi-mi:UHRF1(display_short)|uniprotkb:ICBP90(gene name synonym)|uniprotkb:NP95(gene name synonym)|uniprotkb:RNF106(gene name synonym)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 1(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 1(gene name synonym)|uniprotkb:Inverted CCAAT box-binding protein of 90 kDa(gene name synonym)|uniprotkb:Transcription factor ICBP90(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np95(gene name synonym)|uniprotkb:Nuclear protein 95(gene name synonym)|uniprotkb:RING finger protein 106(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Meilinger et al. (2009) pubmed:19798101|imex:IM-13880|mint:MINT-7296296|doi:10.1038/embor.2009.201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7272167|mint:MINT-7296305|imex:IM-13880-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000088305(gene)|ensembl:ENST00000328111(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0009008"(DNA-methyltransferase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014823"(response to activity)|go:"GO:0031000"(response to caffeine)|go:"GO:0032355"(response to estradiol)|go:"GO:0033189"(response to vitamin A)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030488|interpro:IPR040552|mint:Q9UBC3|rcsb pdb:3FLG|rcsb pdb:3QKJ|rcsb pdb:5CIU|rcsb pdb:5NR3|rcsb pdb:5NRR|rcsb pdb:5NRV|rcsb pdb:5NV0|rcsb pdb:5NV2|rcsb pdb:5NV7|rcsb pdb:5NVO|rcsb pdb:6KDA|rcsb pdb:6KDB|rcsb pdb:6KDL|rcsb pdb:6KDP|rcsb pdb:6KDT|rcsb pdb:6PA7|rcsb pdb:6R3E|rcsb pdb:6U8P|rcsb pdb:6U8V|rcsb pdb:6U8W|rcsb pdb:6U8X|rcsb pdb:5NRS|rcsb pdb:6U90|rcsb pdb:6U91|reactome:R-HSA-212300|reactome:R-HSA-427413|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|ensembl:ENST00000353855|ensembl:ENSP00000313397|ensembl:ENST00000443239|ensembl:ENSP00000403169|ensembl:ENST00000456297|ensembl:ENSP00000412305|ensembl:ENST00000201963|ensembl:ENSP00000201963|ensembl:ENSP00000328547|ensembl:ENST00000348286|ensembl:ENSP00000337764|refseq:NP_001193984.1|refseq:NP_001193985.1|refseq:NP_008823.1|refseq:NP_787044.1|refseq:NP_787045.1|refseq:NP_787046.1|dip:DIP-30000N|mint:MINT-7296308(identity) refseq:NP_001276979.1|refseq:NP_001276980.1|refseq:NP_001276981.1|refseq:NP_037414.3|refseq:NP_001041666.1|ensembl:ENSG00000276043(gene)|ensembl:ENST00000612630(transcript)|ensembl:ENST00000615884(transcript)|ensembl:ENST00000616255(transcript)|ensembl:ENST00000624301(transcript)|ensembl:ENST00000650932(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR000626(Ubiquitin)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|mint:Q96T88|rcsb pdb:2FAZ|rcsb pdb:2L3R|rcsb pdb:2LGG|rcsb pdb:2LGK|rcsb pdb:2LGL|rcsb pdb:2PB7|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3BI7|rcsb pdb:3CLZ|rcsb pdb:3DB3|rcsb pdb:3DB4|rcsb pdb:3DWH|rcsb pdb:3FL2|rcsb pdb:3SHB|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3SOX|rcsb pdb:3T6R|rcsb pdb:3ZVY|rcsb pdb:3ZVZ|rcsb pdb:4GY5|rcsb pdb:4QQD|rcsb pdb:5C6D|rcsb pdb:5IAY|rcsb pdb:5XPI|rcsb pdb:5YY9|rcsb pdb:5YYA|rcsb pdb:6B9M|rcsb pdb:6IIW|rcsb pdb:6VCS|rcsb pdb:6VED|rcsb pdb:6VYJ|rcsb pdb:6W92|reactome:R-HSA-5334118|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-7296307(identity) - - - figure legend:sf1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2009/11/05 2014/10/16 rogid:xxbu/yvuQ1KnhVE/FdTh9CyA6jw9606 rogid:AbWLjSoRl82HTcjZlG4DRavDdGc9606 intact-crc:999768DEA12FBF44|rigid:CH/Jr54jUjCu+ccmnxjDtPfFrI4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant)