#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P00517 uniprotkb:P63251 intact:EBI-7251007|intact:UNK-6019876|ensembl:ENSBTAP00000063436 intact:EBI-7250981|uniprotkb:P35562|intact:MINT-7260243|ensembl:ENSRNOP00000007335 psi-mi:kapca_bovin(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short) psi-mi:kcnj3_rat(display_long)|uniprotkb:Kcnj3(gene name)|psi-mi:Kcnj3(display_short)|uniprotkb:Girk1(gene name synonym)|uniprotkb:Kga(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 3(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir3.1"(gene name synonym)|uniprotkb:KGA(gene name synonym)|uniprotkb:KGB1(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Müllner et al. (2009) pubmed:19765080|imex:IM-13857|mint:MINT-7260238|mint:fj-09-0738 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7250976|mint:MINT-7260270|imex:IM-13857-6 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_777009.1|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043197"(dendritic spine)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P00517|rcsb pdb:1KMU|rcsb pdb:1KMW|rcsb pdb:1Q24|rcsb pdb:1Q61|rcsb pdb:1Q62|rcsb pdb:1Q8T|rcsb pdb:1Q8U|rcsb pdb:1Q8W|rcsb pdb:1SMH|rcsb pdb:1STC|rcsb pdb:1SVE|rcsb pdb:1SVG|rcsb pdb:1SVH|rcsb pdb:1SZM|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:1YDR|rcsb pdb:1YDS|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2F7X|rcsb pdb:2F7Z|rcsb pdb:2GFC|rcsb pdb:2GNF|rcsb pdb:2GNG|rcsb pdb:2GNH|rcsb pdb:2GNI|rcsb pdb:2GNJ|rcsb pdb:2GNL|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2OH0|rcsb pdb:2OJF|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:1YDT|rcsb pdb:2UW4|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|ensembl:ENSBTAG00000006642(gene)|ensembl:ENSBTAT00000085342(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016607"(nuclear speck)|rcsb pdb:3E8C|rcsb pdb:3E8E|rcsb pdb:3KKV|rcsb pdb:3ZO1|rcsb pdb:3ZO2|rcsb pdb:3ZO3|rcsb pdb:3ZO4|rcsb pdb:2UZT|rcsb pdb:4AXA|rcsb pdb:4C33|rcsb pdb:4C34|rcsb pdb:2UZU|rcsb pdb:4C35|rcsb pdb:4C36|rcsb pdb:4C37|rcsb pdb:4C38|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4YXR|rcsb pdb:4YXS|rcsb pdb:4Z83|rcsb pdb:2UZV|rcsb pdb:4Z84|rcsb pdb:2UZW|rcsb pdb:5VHB|rcsb pdb:5VI9|rcsb pdb:5VIB|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AG9|rcsb pdb:3BWJ|rcsb pdb:3DND|rcsb pdb:3DNE|mint:MINT-7260273(identity) rgd:2958|refseq:NP_113798.1|ensembl:ENSRNOG00000005369(gene)|ensembl:ENSRNOT00000007335(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015467"(G-protein activated inward rectifier potassium channel activity)|go:"GO:0030315"(T-tubule)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003274(Potassium channel, inwardly rectifying, Kir3.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P63251|rcsb pdb:1N9P|reactome:R-RNO-1296041|reactome:R-RNO-997272|mint:MINT-7260272(identity) - comment:mint|function:Phosphorylates a large number of substrates in the cytoplasm and the nucleus comment:mint figure legend:F2A F2B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/08/25 2014/10/16 rogid:NNlbK7euZ3jgEnDgP07As8Pesh49913 rogid:McZpctutHa2KxC0mMu6y6dT4JAU10116 intact-crc:DE0DE5B739B8FF7A|rigid:IXGgFWIciMNag3zD89zZBVWAR3o false - binding-associated region:362-410(MINT-7260282)|glutathione s tranferase tag:?-?(MINT-7260279) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P63251 uniprotkb:P00517 intact:EBI-7250981|uniprotkb:P35562|intact:MINT-7260243|ensembl:ENSRNOP00000007335 intact:EBI-7251007|intact:UNK-6019876|ensembl:ENSBTAP00000063436 psi-mi:kcnj3_rat(display_long)|uniprotkb:Kcnj3(gene name)|psi-mi:Kcnj3(display_short)|uniprotkb:Girk1(gene name synonym)|uniprotkb:Kga(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 3(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir3.1"(gene name synonym)|uniprotkb:KGA(gene name synonym)|uniprotkb:KGB1(gene name synonym) psi-mi:kapca_bovin(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short) psi-mi:"MI:0424"(protein kinase assay) Müllner et al. (2009) pubmed:19765080|imex:IM-13857|mint:MINT-7260238|mint:fj-09-0738 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7251147|mint:MINT-7260296|imex:IM-13857-1 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2958|refseq:NP_113798.1|ensembl:ENSRNOG00000005369(gene)|ensembl:ENSRNOT00000007335(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015467"(G-protein activated inward rectifier potassium channel activity)|go:"GO:0030315"(T-tubule)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003274(Potassium channel, inwardly rectifying, Kir3.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P63251|rcsb pdb:1N9P|reactome:R-RNO-1296041|reactome:R-RNO-997272|mint:MINT-7260298(identity) refseq:NP_777009.1|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043197"(dendritic spine)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P00517|rcsb pdb:1KMU|rcsb pdb:1KMW|rcsb pdb:1Q24|rcsb pdb:1Q61|rcsb pdb:1Q62|rcsb pdb:1Q8T|rcsb pdb:1Q8U|rcsb pdb:1Q8W|rcsb pdb:1SMH|rcsb pdb:1STC|rcsb pdb:1SVE|rcsb pdb:1SVG|rcsb pdb:1SVH|rcsb pdb:1SZM|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:1YDR|rcsb pdb:1YDS|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2F7X|rcsb pdb:2F7Z|rcsb pdb:2GFC|rcsb pdb:2GNF|rcsb pdb:2GNG|rcsb pdb:2GNH|rcsb pdb:2GNI|rcsb pdb:2GNJ|rcsb pdb:2GNL|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2OH0|rcsb pdb:2OJF|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:1YDT|rcsb pdb:2UW4|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|ensembl:ENSBTAG00000006642(gene)|ensembl:ENSBTAT00000085342(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016607"(nuclear speck)|rcsb pdb:3E8C|rcsb pdb:3E8E|rcsb pdb:3KKV|rcsb pdb:3ZO1|rcsb pdb:3ZO2|rcsb pdb:3ZO3|rcsb pdb:3ZO4|rcsb pdb:2UZT|rcsb pdb:4AXA|rcsb pdb:4C33|rcsb pdb:4C34|rcsb pdb:2UZU|rcsb pdb:4C35|rcsb pdb:4C36|rcsb pdb:4C37|rcsb pdb:4C38|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4YXR|rcsb pdb:4YXS|rcsb pdb:4Z83|rcsb pdb:2UZV|rcsb pdb:4Z84|rcsb pdb:2UZW|rcsb pdb:5VHB|rcsb pdb:5VI9|rcsb pdb:5VIB|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AG9|rcsb pdb:3BWJ|rcsb pdb:3DND|rcsb pdb:3DNE|mint:MINT-7260310(identity) - comment:mint comment:mint|function:Phosphorylates a large number of substrates in the cytoplasm and the nucleus figure legend:F2C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/08/25 2014/10/16 rogid:McZpctutHa2KxC0mMu6y6dT4JAU10116 rogid:NNlbK7euZ3jgEnDgP07As8Pesh49913 intact-crc:B027B3AF9FC67A2E|rigid:IXGgFWIciMNag3zD89zZBVWAR3o false glutathione s tranferase tag:?-?(MINT-7260307)|binding-associated region:183-501(MINT-7260305)|mutation disrupting interaction:385-385(MINT-7260303)|mutation disrupting interaction:401-501(MINT-7260301) - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63251 uniprotkb:P00517 intact:EBI-7250981|uniprotkb:P35562|intact:MINT-7260243|ensembl:ENSRNOP00000007335 intact:EBI-7251007|intact:UNK-6019876|ensembl:ENSBTAP00000063436 psi-mi:kcnj3_rat(display_long)|uniprotkb:Kcnj3(gene name)|psi-mi:Kcnj3(display_short)|uniprotkb:Girk1(gene name synonym)|uniprotkb:Kga(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 3(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir3.1"(gene name synonym)|uniprotkb:KGA(gene name synonym)|uniprotkb:KGB1(gene name synonym) psi-mi:kapca_bovin(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short) psi-mi:"MI:0424"(protein kinase assay) Müllner et al. (2009) pubmed:19765080|imex:IM-13857|mint:MINT-7260238|mint:fj-09-0738 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7251190|mint:MINT-7260317|imex:IM-13857-2 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2958|refseq:NP_113798.1|ensembl:ENSRNOG00000005369(gene)|ensembl:ENSRNOT00000007335(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015467"(G-protein activated inward rectifier potassium channel activity)|go:"GO:0030315"(T-tubule)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003274(Potassium channel, inwardly rectifying, Kir3.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P63251|rcsb pdb:1N9P|reactome:R-RNO-1296041|reactome:R-RNO-997272|mint:MINT-7260321(identity) refseq:NP_777009.1|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043197"(dendritic spine)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P00517|rcsb pdb:1KMU|rcsb pdb:1KMW|rcsb pdb:1Q24|rcsb pdb:1Q61|rcsb pdb:1Q62|rcsb pdb:1Q8T|rcsb pdb:1Q8U|rcsb pdb:1Q8W|rcsb pdb:1SMH|rcsb pdb:1STC|rcsb pdb:1SVE|rcsb pdb:1SVG|rcsb pdb:1SVH|rcsb pdb:1SZM|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:1YDR|rcsb pdb:1YDS|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2F7X|rcsb pdb:2F7Z|rcsb pdb:2GFC|rcsb pdb:2GNF|rcsb pdb:2GNG|rcsb pdb:2GNH|rcsb pdb:2GNI|rcsb pdb:2GNJ|rcsb pdb:2GNL|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2OH0|rcsb pdb:2OJF|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:1YDT|rcsb pdb:2UW4|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|ensembl:ENSBTAG00000006642(gene)|ensembl:ENSBTAT00000085342(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016607"(nuclear speck)|rcsb pdb:3E8C|rcsb pdb:3E8E|rcsb pdb:3KKV|rcsb pdb:3ZO1|rcsb pdb:3ZO2|rcsb pdb:3ZO3|rcsb pdb:3ZO4|rcsb pdb:2UZT|rcsb pdb:4AXA|rcsb pdb:4C33|rcsb pdb:4C34|rcsb pdb:2UZU|rcsb pdb:4C35|rcsb pdb:4C36|rcsb pdb:4C37|rcsb pdb:4C38|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4YXR|rcsb pdb:4YXS|rcsb pdb:4Z83|rcsb pdb:2UZV|rcsb pdb:4Z84|rcsb pdb:2UZW|rcsb pdb:5VHB|rcsb pdb:5VI9|rcsb pdb:5VIB|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AG9|rcsb pdb:3BWJ|rcsb pdb:3DND|rcsb pdb:3DNE|mint:MINT-7260319(identity) - comment:mint comment:mint|function:Phosphorylates a large number of substrates in the cytoplasm and the nucleus figure legend:F2C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/08/25 2014/10/16 rogid:McZpctutHa2KxC0mMu6y6dT4JAU10116 rogid:NNlbK7euZ3jgEnDgP07As8Pesh49913 intact-crc:886B5D47FC372076|rigid:IXGgFWIciMNag3zD89zZBVWAR3o false glutathione s tranferase tag:?-?(MINT-7260324)|mutation decreasing interaction:385-385(MINT-7260328)|binding-associated region:183-501(MINT-7260326) - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63251 uniprotkb:P00517 intact:EBI-7250981|uniprotkb:P35562|intact:MINT-7260243|ensembl:ENSRNOP00000007335 intact:EBI-7251007|intact:UNK-6019876|ensembl:ENSBTAP00000063436 psi-mi:kcnj3_rat(display_long)|uniprotkb:Kcnj3(gene name)|psi-mi:Kcnj3(display_short)|uniprotkb:Girk1(gene name synonym)|uniprotkb:Kga(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 3(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir3.1"(gene name synonym)|uniprotkb:KGA(gene name synonym)|uniprotkb:KGB1(gene name synonym) psi-mi:kapca_bovin(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short) psi-mi:"MI:0424"(protein kinase assay) Müllner et al. (2009) pubmed:19765080|imex:IM-13857|mint:MINT-7260238|mint:fj-09-0738 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7251248|mint:MINT-7260347|imex:IM-13857-4 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2958|refseq:NP_113798.1|ensembl:ENSRNOG00000005369(gene)|ensembl:ENSRNOT00000007335(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015467"(G-protein activated inward rectifier potassium channel activity)|go:"GO:0030315"(T-tubule)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003274(Potassium channel, inwardly rectifying, Kir3.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P63251|rcsb pdb:1N9P|reactome:R-RNO-1296041|reactome:R-RNO-997272|mint:MINT-7260351(identity) refseq:NP_777009.1|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043197"(dendritic spine)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P00517|rcsb pdb:1KMU|rcsb pdb:1KMW|rcsb pdb:1Q24|rcsb pdb:1Q61|rcsb pdb:1Q62|rcsb pdb:1Q8T|rcsb pdb:1Q8U|rcsb pdb:1Q8W|rcsb pdb:1SMH|rcsb pdb:1STC|rcsb pdb:1SVE|rcsb pdb:1SVG|rcsb pdb:1SVH|rcsb pdb:1SZM|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:1YDR|rcsb pdb:1YDS|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2F7X|rcsb pdb:2F7Z|rcsb pdb:2GFC|rcsb pdb:2GNF|rcsb pdb:2GNG|rcsb pdb:2GNH|rcsb pdb:2GNI|rcsb pdb:2GNJ|rcsb pdb:2GNL|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2OH0|rcsb pdb:2OJF|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:1YDT|rcsb pdb:2UW4|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|ensembl:ENSBTAG00000006642(gene)|ensembl:ENSBTAT00000085342(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016607"(nuclear speck)|rcsb pdb:3E8C|rcsb pdb:3E8E|rcsb pdb:3KKV|rcsb pdb:3ZO1|rcsb pdb:3ZO2|rcsb pdb:3ZO3|rcsb pdb:3ZO4|rcsb pdb:2UZT|rcsb pdb:4AXA|rcsb pdb:4C33|rcsb pdb:4C34|rcsb pdb:2UZU|rcsb pdb:4C35|rcsb pdb:4C36|rcsb pdb:4C37|rcsb pdb:4C38|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4YXR|rcsb pdb:4YXS|rcsb pdb:4Z83|rcsb pdb:2UZV|rcsb pdb:4Z84|rcsb pdb:2UZW|rcsb pdb:5VHB|rcsb pdb:5VI9|rcsb pdb:5VIB|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AG9|rcsb pdb:3BWJ|rcsb pdb:3DND|rcsb pdb:3DNE|mint:MINT-7260349(identity) - comment:mint comment:mint|function:Phosphorylates a large number of substrates in the cytoplasm and the nucleus figure legend:F2C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/08/25 2014/10/16 rogid:McZpctutHa2KxC0mMu6y6dT4JAU10116 rogid:NNlbK7euZ3jgEnDgP07As8Pesh49913 intact-crc:E0FA5B764F106BAA|rigid:IXGgFWIciMNag3zD89zZBVWAR3o false glutathione s tranferase tag:?-?(MINT-7260352)|binding-associated region:183-501(MINT-7260354)|mutation decreasing interaction:407-407(MINT-7260356) - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00517 uniprotkb:P63251 intact:EBI-7251007|intact:UNK-6019876|ensembl:ENSBTAP00000063436 intact:EBI-7250981|uniprotkb:P35562|intact:MINT-7260243|ensembl:ENSRNOP00000007335 psi-mi:kapca_bovin(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short) psi-mi:kcnj3_rat(display_long)|uniprotkb:Kcnj3(gene name)|psi-mi:Kcnj3(display_short)|uniprotkb:Girk1(gene name synonym)|uniprotkb:Kga(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 3(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir3.1"(gene name synonym)|uniprotkb:KGA(gene name synonym)|uniprotkb:KGB1(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Müllner et al. (2009) pubmed:19765080|imex:IM-13857|mint:MINT-7260238|mint:fj-09-0738 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7251227|mint:MINT-7260333|imex:IM-13857-3 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_777009.1|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043197"(dendritic spine)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P00517|rcsb pdb:1KMU|rcsb pdb:1KMW|rcsb pdb:1Q24|rcsb pdb:1Q61|rcsb pdb:1Q62|rcsb pdb:1Q8T|rcsb pdb:1Q8U|rcsb pdb:1Q8W|rcsb pdb:1SMH|rcsb pdb:1STC|rcsb pdb:1SVE|rcsb pdb:1SVG|rcsb pdb:1SVH|rcsb pdb:1SZM|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:1YDR|rcsb pdb:1YDS|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2F7X|rcsb pdb:2F7Z|rcsb pdb:2GFC|rcsb pdb:2GNF|rcsb pdb:2GNG|rcsb pdb:2GNH|rcsb pdb:2GNI|rcsb pdb:2GNJ|rcsb pdb:2GNL|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2OH0|rcsb pdb:2OJF|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:1YDT|rcsb pdb:2UW4|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|ensembl:ENSBTAG00000006642(gene)|ensembl:ENSBTAT00000085342(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016607"(nuclear speck)|rcsb pdb:3E8C|rcsb pdb:3E8E|rcsb pdb:3KKV|rcsb pdb:3ZO1|rcsb pdb:3ZO2|rcsb pdb:3ZO3|rcsb pdb:3ZO4|rcsb pdb:2UZT|rcsb pdb:4AXA|rcsb pdb:4C33|rcsb pdb:4C34|rcsb pdb:2UZU|rcsb pdb:4C35|rcsb pdb:4C36|rcsb pdb:4C37|rcsb pdb:4C38|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4YXR|rcsb pdb:4YXS|rcsb pdb:4Z83|rcsb pdb:2UZV|rcsb pdb:4Z84|rcsb pdb:2UZW|rcsb pdb:5VHB|rcsb pdb:5VI9|rcsb pdb:5VIB|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AG9|rcsb pdb:3BWJ|rcsb pdb:3DND|rcsb pdb:3DNE|mint:MINT-7260343(identity) rgd:2958|refseq:NP_113798.1|ensembl:ENSRNOG00000005369(gene)|ensembl:ENSRNOT00000007335(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015467"(G-protein activated inward rectifier potassium channel activity)|go:"GO:0030315"(T-tubule)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003274(Potassium channel, inwardly rectifying, Kir3.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P63251|rcsb pdb:1N9P|reactome:R-RNO-1296041|reactome:R-RNO-997272|mint:MINT-7260335(identity) - comment:mint|function:Phosphorylates a large number of substrates in the cytoplasm and the nucleus comment:mint figure legend:F2C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/08/25 2014/10/16 rogid:NNlbK7euZ3jgEnDgP07As8Pesh49913 rogid:McZpctutHa2KxC0mMu6y6dT4JAU10116 intact-crc:0EFADE304F10B4B3|rigid:IXGgFWIciMNag3zD89zZBVWAR3o false - mutation decreasing interaction:401-401(MINT-7260336)|glutathione s tranferase tag:?-?(MINT-7260340)|binding-associated region:183-501(MINT-7260338) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P63251 uniprotkb:P00517 intact:EBI-7250981|uniprotkb:P35562|intact:MINT-7260243|ensembl:ENSRNOP00000007335 intact:EBI-7251007|intact:UNK-6019876|ensembl:ENSBTAP00000063436 psi-mi:kcnj3_rat(display_long)|uniprotkb:Kcnj3(gene name)|psi-mi:Kcnj3(display_short)|uniprotkb:Girk1(gene name synonym)|uniprotkb:Kga(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 3(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir3.1"(gene name synonym)|uniprotkb:KGA(gene name synonym)|uniprotkb:KGB1(gene name synonym) psi-mi:kapca_bovin(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short) psi-mi:"MI:0424"(protein kinase assay) Müllner et al. (2009) pubmed:19765080|imex:IM-13857|mint:MINT-7260238|mint:fj-09-0738 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7251274|mint:MINT-7260361|imex:IM-13857-5 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2958|refseq:NP_113798.1|ensembl:ENSRNOG00000005369(gene)|ensembl:ENSRNOT00000007335(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015467"(G-protein activated inward rectifier potassium channel activity)|go:"GO:0030315"(T-tubule)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003274(Potassium channel, inwardly rectifying, Kir3.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P63251|rcsb pdb:1N9P|reactome:R-RNO-1296041|reactome:R-RNO-997272|mint:MINT-7260363(identity) refseq:NP_777009.1|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043197"(dendritic spine)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P00517|rcsb pdb:1KMU|rcsb pdb:1KMW|rcsb pdb:1Q24|rcsb pdb:1Q61|rcsb pdb:1Q62|rcsb pdb:1Q8T|rcsb pdb:1Q8U|rcsb pdb:1Q8W|rcsb pdb:1SMH|rcsb pdb:1STC|rcsb pdb:1SVE|rcsb pdb:1SVG|rcsb pdb:1SVH|rcsb pdb:1SZM|rcsb pdb:1VEB|rcsb pdb:1XH4|rcsb pdb:1XH5|rcsb pdb:1XH6|rcsb pdb:1XH7|rcsb pdb:1XH8|rcsb pdb:1XH9|rcsb pdb:1XHA|rcsb pdb:1YDR|rcsb pdb:1YDS|rcsb pdb:2C1A|rcsb pdb:2C1B|rcsb pdb:2F7E|rcsb pdb:2F7X|rcsb pdb:2F7Z|rcsb pdb:2GFC|rcsb pdb:2GNF|rcsb pdb:2GNG|rcsb pdb:2GNH|rcsb pdb:2GNI|rcsb pdb:2GNJ|rcsb pdb:2GNL|rcsb pdb:2JDS|rcsb pdb:2JDT|rcsb pdb:2JDV|rcsb pdb:2OH0|rcsb pdb:2OJF|rcsb pdb:2UVX|rcsb pdb:2UVY|rcsb pdb:2UVZ|rcsb pdb:2UW0|rcsb pdb:2UW3|rcsb pdb:1YDT|rcsb pdb:2UW4|rcsb pdb:2UW5|rcsb pdb:2UW6|rcsb pdb:2UW7|rcsb pdb:2UW8|ensembl:ENSBTAG00000006642(gene)|ensembl:ENSBTAT00000085342(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016607"(nuclear speck)|rcsb pdb:3E8C|rcsb pdb:3E8E|rcsb pdb:3KKV|rcsb pdb:3ZO1|rcsb pdb:3ZO2|rcsb pdb:3ZO3|rcsb pdb:3ZO4|rcsb pdb:2UZT|rcsb pdb:4AXA|rcsb pdb:4C33|rcsb pdb:4C34|rcsb pdb:2UZU|rcsb pdb:4C35|rcsb pdb:4C36|rcsb pdb:4C37|rcsb pdb:4C38|rcsb pdb:4IE9|rcsb pdb:4IJ9|rcsb pdb:4YXR|rcsb pdb:4YXS|rcsb pdb:4Z83|rcsb pdb:2UZV|rcsb pdb:4Z84|rcsb pdb:2UZW|rcsb pdb:5VHB|rcsb pdb:5VI9|rcsb pdb:5VIB|rcsb pdb:6E99|rcsb pdb:6E9L|rcsb pdb:2VNW|rcsb pdb:2VNY|rcsb pdb:2VO0|rcsb pdb:2VO3|rcsb pdb:2VO6|rcsb pdb:2VO7|rcsb pdb:3AG9|rcsb pdb:3BWJ|rcsb pdb:3DND|rcsb pdb:3DNE|mint:MINT-7260375(identity) - comment:mint comment:mint|function:Phosphorylates a large number of substrates in the cytoplasm and the nucleus figure legend:F2C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/08/25 2014/10/16 rogid:McZpctutHa2KxC0mMu6y6dT4JAU10116 rogid:NNlbK7euZ3jgEnDgP07As8Pesh49913 intact-crc:B2568B39C78B7530|rigid:IXGgFWIciMNag3zD89zZBVWAR3o false glutathione s tranferase tag:?-?(MINT-7260372)|binding-associated region:183-501(MINT-7260370)|mutation disrupting interaction:407-407(MINT-7260364)|mutation disrupting interaction:385-385(MINT-7260368)|mutation disrupting interaction:401-401(MINT-7260366) - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0396"(predetermined participant)