#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O94646	uniprotkb:O74825	intact:EBI-1533413|ensemblfungi:"SPBC21.04.1:pep"	intact:EBI-697320|ensemblfungi:"SPBC337.14.1:pep"	psi-mi:med8_schpo(display_long)|uniprotkb:med8(gene name)|psi-mi:med8(display_short)|uniprotkb:sep15(gene name synonym)|uniprotkb:SPBC21.04(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Cell separation protein sep15(gene name synonym)	psi-mi:rpb4_schpo(display_long)|uniprotkb:rpb4(gene name)|psi-mi:rpb4(display_short)|uniprotkb:SPBC337.14(orf name)	psi-mi:"MI:0018"(two hybrid)	Mehta et al. (2009)	pubmed:19720063|imex:IM-13801|mint:MINT-7260712|mint:d-09-01599	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7200963|mint:MINT-7260720|imex:IM-13801-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_596338.1|mint:O94646|dip:DIP-38755N|ensemblfungi:SPBC21.04(gene)|ensemblfungi:SPBC21.04.1(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:3C0T|rcsb pdb:4H63|rcsb pdb:5N9J|rcsb pdb:5U0P|rcsb pdb:5U0S|mint:MINT-7260723(identity)	refseq:NP_595415.1|interpro:IPR010997(HRDC-like)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|mint:O74825|interpro:IPR038324|ensemblfungi:SPBC337.14(gene)|ensemblfungi:SPBC337.14.1(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|rcsb pdb:3H0G|rcsb pdb:5U0S|reactome:R-SPO-113418|reactome:R-SPO-5578749|reactome:R-SPO-674695|reactome:R-SPO-6781823|reactome:R-SPO-6782135|reactome:R-SPO-6782210|reactome:R-SPO-6796648|reactome:R-SPO-6807505|reactome:R-SPO-72086|reactome:R-SPO-72165|reactome:R-SPO-73776|reactome:R-SPO-73779|reactome:R-SPO-75953|reactome:R-SPO-75955|reactome:R-SPO-76042|reactome:R-SPO-77075|reactome:R-SPO-9018519|mint:MINT-7260722(identity)	-	crc64:A61A9E49B83A86F0	-	figure legend:F1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/08/26	2014/10/16	rogid:mLCQ3N8/dJ0OnkFQE4BxpBQhn4c284812	rogid:8Dlb3QqZdUiDpw1DLmRJVIX6/cU284812	intact-crc:4EC419332D7D545B|rigid:LWLqgeoYatgsJl3aIiSVkaT5fPE	false	tag:?-?(MINT-7260728)	tag:?-?(MINT-7260724)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O94646	uniprotkb:O74825	intact:EBI-1533413|ensemblfungi:"SPBC21.04.1:pep"	intact:EBI-697320|ensemblfungi:"SPBC337.14.1:pep"	psi-mi:med8_schpo(display_long)|uniprotkb:med8(gene name)|psi-mi:med8(display_short)|uniprotkb:sep15(gene name synonym)|uniprotkb:SPBC21.04(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Cell separation protein sep15(gene name synonym)	psi-mi:rpb4_schpo(display_long)|uniprotkb:rpb4(gene name)|psi-mi:rpb4(display_short)|uniprotkb:SPBC337.14(orf name)	psi-mi:"MI:0018"(two hybrid)	Mehta et al. (2009)	pubmed:19720063|imex:IM-13801|mint:MINT-7260712|mint:d-09-01599	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7200980|mint:MINT-7260782|imex:IM-13801-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_596338.1|mint:O94646|dip:DIP-38755N|ensemblfungi:SPBC21.04(gene)|ensemblfungi:SPBC21.04.1(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:3C0T|rcsb pdb:4H63|rcsb pdb:5N9J|rcsb pdb:5U0P|rcsb pdb:5U0S|mint:MINT-7260784(identity)	refseq:NP_595415.1|interpro:IPR010997(HRDC-like)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|mint:O74825|interpro:IPR038324|ensemblfungi:SPBC337.14(gene)|ensemblfungi:SPBC337.14.1(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|rcsb pdb:3H0G|rcsb pdb:5U0S|reactome:R-SPO-113418|reactome:R-SPO-5578749|reactome:R-SPO-674695|reactome:R-SPO-6781823|reactome:R-SPO-6782135|reactome:R-SPO-6782210|reactome:R-SPO-6796648|reactome:R-SPO-6807505|reactome:R-SPO-72086|reactome:R-SPO-72165|reactome:R-SPO-73776|reactome:R-SPO-73779|reactome:R-SPO-75953|reactome:R-SPO-75955|reactome:R-SPO-76042|reactome:R-SPO-77075|reactome:R-SPO-9018519|mint:MINT-7260790(identity)	-	crc64:A61A9E49B83A86F0	-	figure legend:F2 F4|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/08/26	2014/10/16	rogid:mLCQ3N8/dJ0OnkFQE4BxpBQhn4c284812	rogid:8Dlb3QqZdUiDpw1DLmRJVIX6/cU284812	intact-crc:8669223C155A9CB4|rigid:LWLqgeoYatgsJl3aIiSVkaT5fPE	false	tag:?-?(MINT-7260787)|binding-associated region:107-200(MINT-7260785)	tag:?-?(MINT-7260791)|mutation disrupting interaction:113-135(MINT-7260797)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O94646	uniprotkb:O74825	intact:EBI-1533413|ensemblfungi:"SPBC21.04.1:pep"	intact:EBI-697320|ensemblfungi:"SPBC337.14.1:pep"	psi-mi:med8_schpo(display_long)|uniprotkb:med8(gene name)|psi-mi:med8(display_short)|uniprotkb:sep15(gene name synonym)|uniprotkb:SPBC21.04(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Cell separation protein sep15(gene name synonym)	psi-mi:rpb4_schpo(display_long)|uniprotkb:rpb4(gene name)|psi-mi:rpb4(display_short)|uniprotkb:SPBC337.14(orf name)	psi-mi:"MI:0096"(pull down)	Mehta et al. (2009)	pubmed:19720063|imex:IM-13801|mint:MINT-7260712|mint:d-09-01599	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7201028|mint:MINT-7260735|imex:IM-13801-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_596338.1|mint:O94646|dip:DIP-38755N|ensemblfungi:SPBC21.04(gene)|ensemblfungi:SPBC21.04.1(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:3C0T|rcsb pdb:4H63|rcsb pdb:5N9J|rcsb pdb:5U0P|rcsb pdb:5U0S|mint:MINT-7260737(identity)	refseq:NP_595415.1|interpro:IPR010997(HRDC-like)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|mint:O74825|interpro:IPR038324|ensemblfungi:SPBC337.14(gene)|ensemblfungi:SPBC337.14.1(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|rcsb pdb:3H0G|rcsb pdb:5U0S|reactome:R-SPO-113418|reactome:R-SPO-5578749|reactome:R-SPO-674695|reactome:R-SPO-6781823|reactome:R-SPO-6782135|reactome:R-SPO-6782210|reactome:R-SPO-6796648|reactome:R-SPO-6807505|reactome:R-SPO-72086|reactome:R-SPO-72165|reactome:R-SPO-73776|reactome:R-SPO-73779|reactome:R-SPO-75953|reactome:R-SPO-75955|reactome:R-SPO-76042|reactome:R-SPO-77075|reactome:R-SPO-9018519|mint:MINT-7260743(identity)	-	crc64:A61A9E49B83A86F0	-	figure legend:F1E|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/08/26	2014/10/16	rogid:mLCQ3N8/dJ0OnkFQE4BxpBQhn4c284812	rogid:8Dlb3QqZdUiDpw1DLmRJVIX6/cU284812	intact-crc:EE1B6DC664243C71|rigid:LWLqgeoYatgsJl3aIiSVkaT5fPE	false	his tag:?-?(MINT-7260740)	glutathione s tranferase tag:?-?(MINT-7260744)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O94646	uniprotkb:O14258	intact:EBI-1533413|ensemblfungi:"SPBC21.04.1:pep"	intact:EBI-7201045|ensemblfungi:"SPAC6G10.12c.1:pep"|intact:MINT-4782350	psi-mi:med8_schpo(display_long)|uniprotkb:med8(gene name)|psi-mi:med8(display_short)|uniprotkb:sep15(gene name synonym)|uniprotkb:SPBC21.04(orf name)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Cell separation protein sep15(gene name synonym)	psi-mi:ace2_schpo(display_long)|uniprotkb:ace2(gene name)|psi-mi:ace2(display_short)|uniprotkb:SPAC6G10.12c(orf name)	psi-mi:"MI:0096"(pull down)	Mehta et al. (2009)	pubmed:19720063|imex:IM-13801|mint:MINT-7260712|mint:d-09-01599	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7201063|mint:MINT-7260753|imex:IM-13801-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_596338.1|mint:O94646|dip:DIP-38755N|ensemblfungi:SPBC21.04(gene)|ensemblfungi:SPBC21.04.1(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:3C0T|rcsb pdb:4H63|rcsb pdb:5N9J|rcsb pdb:5U0P|rcsb pdb:5U0S|mint:MINT-7260759(identity)	mint:O14258|ensemblfungi:SPAC6G10.12c(gene)|ensemblfungi:SPAC6G10.12c.1(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_594109.1|interpro:IPR036236|mint:MINT-7260755(identity)	-	crc64:A61A9E49B83A86F0	comment:mint|function:Regulates the transcription of genes required for cell separation	figure legend:F5|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/08/26	2014/10/16	rogid:mLCQ3N8/dJ0OnkFQE4BxpBQhn4c284812	rogid:tJRBzPv/I+peMMdi7NQowRSjeso284812	intact-crc:9CBADEFE9D206413|rigid:rkqVSBbWq422N79HoT0NvTE/+48	false	his tag:?-?(MINT-7260760)	flag tag:?-?(MINT-7260756)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)