#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q50DL5	uniprotkb:P22315	intact:EBI-7174035|intact:MINT-7233185	intact:EBI-7174007|intact:MINT-1842883	psi-mi:q50dl5_chlae(display_long)|uniprotkb:ATP6(gene name)|psi-mi:ATP6(display_short)	psi-mi:hemh_mouse(display_long)|uniprotkb:Fech(gene name)|psi-mi:Fech(display_short)|uniprotkb:Protoheme ferro-lyase(gene name synonym)|uniprotkb:Heme synthase(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Sakaino et al. (2009)	pubmed:19691493|mint:MINT-7233180|mint:fj-09-0740	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7174048|mint:MINT-7233195	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q50DL5|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045263"("proton-transporting ATP synthase complex, coupling factor F(o)")|interpro:IPR023011|interpro:IPR000568(ATPase, F0 complex, subunit A)|refseq:YP_238247.1|interpro:IPR035908|mint:MINT-7233198(identity)	mint:P22315|interpro:IPR033644|interpro:IPR033659|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009589"(detection of UV)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010999"(regulation of eIF2 alpha phosphorylation by heme)|go:"GO:0020037"(heme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030350"(iron-responsive element binding)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046501"(protoporphyrinogen IX metabolic process)|go:"GO:0046906"(tetrapyrrole binding)|go:"GO:0046984"(regulation of hemoglobin biosynthetic process)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0055072"(iron ion homeostasis)|reactome:R-MMU-189451|go:"GO:0004325"(ferrochelatase activity)|interpro:IPR019772|interpro:IPR001015(Ferrochelatase)|mint:MINT-7233197(identity)	go:"GO:0005739"(mitochondrion)	comment:mint	function:Catalyzes the ferrous insertion into protoporphyrin IX|comment:mint|function:"Defects in Fech are the cause of a viable autosomal recessive mutation (named Fechm1Pas or Fch) that causes jaundice and anemia"	figure legend:f1a|comment:mint	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2009/07/27	2014/10/16	rogid:k3AAXa5MRZUnRwPmHYJ0I2SZNQk9534	rogid:XE7oTrCC8NCTJTGX6SBaphYeSFs10090	intact-crc:04F5C0F07FC42745|rigid:f3TMDSXRQuvyLy8WS0T0kHJgZlw	false	-	ha tag:?-?(MINT-7233203)	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)
uniprotkb:Q61102	uniprotkb:P19783	intact:EBI-6907927|ensembl:ENSMUSP00000033695|uniprotkb:A2AC46|uniprotkb:Q3U7S8	intact:EBI-7174084|ensembl:ENSMUSP00000034276|ensembl:ENSMUSP00000138019|uniprotkb:Q545A9|intact:MINT-1860013	psi-mi:abcb7_mouse(display_long)|uniprotkb:Abcb7(gene name)|psi-mi:Abcb7(display_short)|uniprotkb:Abc7(gene name synonym)|uniprotkb:ATP-binding cassette transporter 7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 7, mitochondrial(gene name synonym)	psi-mi:cox41_mouse(display_long)|uniprotkb:Cox4i1(gene name)|psi-mi:Cox4i1(display_short)|uniprotkb:Cox4(gene name synonym)|uniprotkb:Cox4a(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit IV isoform 1(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide IV(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Sakaino et al. (2009)	pubmed:19691493|mint:MINT-7233180|mint:fj-09-0740	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7174103|mint:MINT-7233207	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036640|interpro:IPR039421|mint:Q61102|reactome:R-MMU-1369007|ensembl:ENSMUSG00000031333(gene)|ensembl:ENSMUST00000033695(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070455"(positive regulation of heme biosynthetic process)|go:"GO:0140466"(iron-sulfur cluster export from the mitochondrion)|go:"GO:0140481"(ABC-type iron-sulfur cluster transporter activity)|go:"GO:1903331"(positive regulation of iron-sulfur cluster assembly)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|go:"GO:0005743"(mitochondrial inner membrane)|refseq:NP_033722.1|mint:MINT-7233210(identity)	refseq:NP_001280488.1|refseq:NP_034071.2|ensembl:ENSMUSG00000031818(gene)|ensembl:ENSMUST00000034276(transcript)|ensembl:ENSMUST00000181586(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0005829"(cytosol)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007584"(response to nutrient)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR004203(Cytochrome c oxidase subunit IV)|interpro:IPR013288(Cytochrome c oxidase subunit 4)|interpro:IPR036639|mint:P19783|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564|mint:MINT-7233221(identity)	go:"GO:0005743"(mitochondrial inner membrane)	-	function:This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport|comment:mint	comment:homomint|figure legend:f2a f2c|comment:mint	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2009/07/27	2014/10/16	rogid:+27KEQlgfCk6DppRFipTKUUS0wo10090	rogid:zt2qwV/jVAo1B9UISW8R2votzlU10090	intact-crc:A5A16DC59D232A31|rigid:Y31+EtMFbr+ZgELt7UukG8AycQY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q61102	uniprotkb:P22315	intact:EBI-6907927|ensembl:ENSMUSP00000033695|uniprotkb:A2AC46|uniprotkb:Q3U7S8	intact:EBI-7174007|intact:MINT-1842883	psi-mi:abcb7_mouse(display_long)|uniprotkb:Abcb7(gene name)|psi-mi:Abcb7(display_short)|uniprotkb:Abc7(gene name synonym)|uniprotkb:ATP-binding cassette transporter 7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 7, mitochondrial(gene name synonym)	psi-mi:hemh_mouse(display_long)|uniprotkb:Fech(gene name)|psi-mi:Fech(display_short)|uniprotkb:Protoheme ferro-lyase(gene name synonym)|uniprotkb:Heme synthase(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Sakaino et al. (2009)	pubmed:19691493|mint:MINT-7233180|mint:fj-09-0740	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7174103|mint:MINT-7233207	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036640|interpro:IPR039421|mint:Q61102|reactome:R-MMU-1369007|ensembl:ENSMUSG00000031333(gene)|ensembl:ENSMUST00000033695(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070455"(positive regulation of heme biosynthetic process)|go:"GO:0140466"(iron-sulfur cluster export from the mitochondrion)|go:"GO:0140481"(ABC-type iron-sulfur cluster transporter activity)|go:"GO:1903331"(positive regulation of iron-sulfur cluster assembly)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|go:"GO:0005743"(mitochondrial inner membrane)|refseq:NP_033722.1|mint:MINT-7233210(identity)	mint:P22315|interpro:IPR033644|interpro:IPR033659|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009589"(detection of UV)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010999"(regulation of eIF2 alpha phosphorylation by heme)|go:"GO:0020037"(heme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030350"(iron-responsive element binding)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046501"(protoporphyrinogen IX metabolic process)|go:"GO:0046906"(tetrapyrrole binding)|go:"GO:0046984"(regulation of hemoglobin biosynthetic process)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0055072"(iron ion homeostasis)|reactome:R-MMU-189451|go:"GO:0004325"(ferrochelatase activity)|interpro:IPR019772|interpro:IPR001015(Ferrochelatase)|mint:MINT-7233212(identity)	go:"GO:0005743"(mitochondrial inner membrane)	-	function:Catalyzes the ferrous insertion into protoporphyrin IX|comment:mint|function:"Defects in Fech are the cause of a viable autosomal recessive mutation (named Fechm1Pas or Fch) that causes jaundice and anemia"	comment:homomint|figure legend:f2a f2c|comment:mint	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2009/07/27	2014/10/16	rogid:+27KEQlgfCk6DppRFipTKUUS0wo10090	rogid:XE7oTrCC8NCTJTGX6SBaphYeSFs10090	intact-crc:A5A16DC59D232A31|rigid:Y31+EtMFbr+ZgELt7UukG8AycQY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q61102	uniprotkb:Q9DCN2	intact:EBI-6907927|ensembl:ENSMUSP00000033695|uniprotkb:A2AC46|uniprotkb:Q3U7S8	intact:EBI-4321444|ensembl:ENSMUSP00000018186	psi-mi:abcb7_mouse(display_long)|uniprotkb:Abcb7(gene name)|psi-mi:Abcb7(display_short)|uniprotkb:Abc7(gene name synonym)|uniprotkb:ATP-binding cassette transporter 7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 7, mitochondrial(gene name synonym)	psi-mi:nb5r3_mouse(display_long)|uniprotkb:Cyb5r3(gene name)|psi-mi:Cyb5r3(display_short)|uniprotkb:Dia1(gene name synonym)|uniprotkb:Diaphorase-1(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Sakaino et al. (2009)	pubmed:19691493|mint:MINT-7233180|mint:fj-09-0740	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7174103|mint:MINT-7233207	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036640|interpro:IPR039421|mint:Q61102|reactome:R-MMU-1369007|ensembl:ENSMUSG00000031333(gene)|ensembl:ENSMUST00000033695(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070455"(positive regulation of heme biosynthetic process)|go:"GO:0140466"(iron-sulfur cluster export from the mitochondrion)|go:"GO:0140481"(ABC-type iron-sulfur cluster transporter activity)|go:"GO:1903331"(positive regulation of iron-sulfur cluster assembly)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|go:"GO:0005743"(mitochondrial inner membrane)|refseq:NP_033722.1|mint:MINT-7233210(identity)	refseq:NP_084063.1|refseq:XP_006520346.1|ensembl:ENSMUSG00000018042(gene)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016208"(AMP binding)|go:"GO:0043531"(ADP binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|ensembl:ENSMUST00000018186(transcript)|go:"GO:0071949"(FAD binding)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|interpro:IPR039261|go:"GO:0051287"(NAD binding)|mint:Q9DCN2|reactome:R-MMU-196836|reactome:R-MMU-211945|reactome:R-MMU-6798695|dip:DIP-57517N|mint:MINT-7233222(identity)	go:"GO:0005743"(mitochondrial inner membrane)	-	-	comment:homomint|figure legend:f2a f2c|comment:mint	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2009/07/27	2014/10/16	rogid:+27KEQlgfCk6DppRFipTKUUS0wo10090	rogid:72QkmF4NeAFyp0tOl6Vxsol0Z6410090	intact-crc:A5A16DC59D232A31|rigid:Y31+EtMFbr+ZgELt7UukG8AycQY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q61102	uniprotkb:P22315	intact:EBI-6907927|ensembl:ENSMUSP00000033695|uniprotkb:A2AC46|uniprotkb:Q3U7S8	intact:EBI-7174007|intact:MINT-1842883	psi-mi:abcb7_mouse(display_long)|uniprotkb:Abcb7(gene name)|psi-mi:Abcb7(display_short)|uniprotkb:Abc7(gene name synonym)|uniprotkb:ATP-binding cassette transporter 7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 7, mitochondrial(gene name synonym)	psi-mi:hemh_mouse(display_long)|uniprotkb:Fech(gene name)|psi-mi:Fech(display_short)|uniprotkb:Protoheme ferro-lyase(gene name synonym)|uniprotkb:Heme synthase(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Sakaino et al. (2009)	pubmed:19691493|mint:MINT-7233180|mint:fj-09-0740	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7174121|mint:MINT-7233234	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036640|interpro:IPR039421|mint:Q61102|reactome:R-MMU-1369007|ensembl:ENSMUSG00000031333(gene)|ensembl:ENSMUST00000033695(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070455"(positive regulation of heme biosynthetic process)|go:"GO:0140466"(iron-sulfur cluster export from the mitochondrion)|go:"GO:0140481"(ABC-type iron-sulfur cluster transporter activity)|go:"GO:1903331"(positive regulation of iron-sulfur cluster assembly)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|go:"GO:0005743"(mitochondrial inner membrane)|refseq:NP_033722.1|mint:MINT-7233241(identity)	mint:P22315|interpro:IPR033644|interpro:IPR033659|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009589"(detection of UV)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010999"(regulation of eIF2 alpha phosphorylation by heme)|go:"GO:0020037"(heme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030350"(iron-responsive element binding)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046501"(protoporphyrinogen IX metabolic process)|go:"GO:0046906"(tetrapyrrole binding)|go:"GO:0046984"(regulation of hemoglobin biosynthetic process)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0055072"(iron ion homeostasis)|reactome:R-MMU-189451|go:"GO:0004325"(ferrochelatase activity)|interpro:IPR019772|interpro:IPR001015(Ferrochelatase)|mint:MINT-7233243(identity)	go:"GO:0005741"(mitochondrial outer membrane)	-	function:Catalyzes the ferrous insertion into protoporphyrin IX|comment:mint|function:"Defects in Fech are the cause of a viable autosomal recessive mutation (named Fechm1Pas or Fch) that causes jaundice and anemia"	comment:homomint|figure legend:f2a f2c|comment:mint	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2009/07/27	2014/10/16	rogid:+27KEQlgfCk6DppRFipTKUUS0wo10090	rogid:XE7oTrCC8NCTJTGX6SBaphYeSFs10090	intact-crc:4A1373EFB4AF044C|rigid:DjRgOS1hvUz0gxEihgvNaCxvmGI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q61102	uniprotkb:Q9DCN2	intact:EBI-6907927|ensembl:ENSMUSP00000033695|uniprotkb:A2AC46|uniprotkb:Q3U7S8	intact:EBI-4321444|ensembl:ENSMUSP00000018186	psi-mi:abcb7_mouse(display_long)|uniprotkb:Abcb7(gene name)|psi-mi:Abcb7(display_short)|uniprotkb:Abc7(gene name synonym)|uniprotkb:ATP-binding cassette transporter 7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 7, mitochondrial(gene name synonym)	psi-mi:nb5r3_mouse(display_long)|uniprotkb:Cyb5r3(gene name)|psi-mi:Cyb5r3(display_short)|uniprotkb:Dia1(gene name synonym)|uniprotkb:Diaphorase-1(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Sakaino et al. (2009)	pubmed:19691493|mint:MINT-7233180|mint:fj-09-0740	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7174121|mint:MINT-7233234	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036640|interpro:IPR039421|mint:Q61102|reactome:R-MMU-1369007|ensembl:ENSMUSG00000031333(gene)|ensembl:ENSMUST00000033695(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070455"(positive regulation of heme biosynthetic process)|go:"GO:0140466"(iron-sulfur cluster export from the mitochondrion)|go:"GO:0140481"(ABC-type iron-sulfur cluster transporter activity)|go:"GO:1903331"(positive regulation of iron-sulfur cluster assembly)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|go:"GO:0005743"(mitochondrial inner membrane)|refseq:NP_033722.1|mint:MINT-7233241(identity)	refseq:NP_084063.1|refseq:XP_006520346.1|ensembl:ENSMUSG00000018042(gene)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016208"(AMP binding)|go:"GO:0043531"(ADP binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|ensembl:ENSMUST00000018186(transcript)|go:"GO:0071949"(FAD binding)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|interpro:IPR039261|go:"GO:0051287"(NAD binding)|mint:Q9DCN2|reactome:R-MMU-196836|reactome:R-MMU-211945|reactome:R-MMU-6798695|dip:DIP-57517N|mint:MINT-7233237(identity)	go:"GO:0005741"(mitochondrial outer membrane)	-	-	comment:homomint|figure legend:f2a f2c|comment:mint	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2009/07/27	2014/10/16	rogid:+27KEQlgfCk6DppRFipTKUUS0wo10090	rogid:72QkmF4NeAFyp0tOl6Vxsol0Z6410090	intact-crc:4A1373EFB4AF044C|rigid:DjRgOS1hvUz0gxEihgvNaCxvmGI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)