#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P04233 uniprotkb:P61073 intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530 intact:EBI-489411|uniprotkb:Q53S69|uniprotkb:O60835|uniprotkb:P30991|uniprotkb:P56438|uniprotkb:Q9UKN2|uniprotkb:B2R5N0|uniprotkb:Q9BXA0|ensembl:ENSP00000241393 psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short) psi-mi:cxcr4_human(display_long)|uniprotkb:Stromal cell-derived factor 1 receptor(gene name synonym)|uniprotkb:Fusin(gene name synonym)|uniprotkb:Leukocyte-derived seven transmembrane domain receptor(gene name synonym)|uniprotkb:LCR1(gene name synonym)|uniprotkb:FB22(gene name synonym)|uniprotkb:NPYRL(gene name synonym)|uniprotkb:HM89(gene name synonym)|uniprotkb:CXCR4(gene name)|psi-mi:CXCR4(display_short)|uniprotkb:Lipopolysaccharide-associated protein 3(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Schwartz et al. (2009) pubmed:19665027|mint:MINT-7234485|mint:d-09-00737 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7156615|mint:MINT-7234499 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|mint:MINT-7234501(identity) refseq:NP_001008540.1|refseq:NP_003458.1|refseq:NP_001334985.1|refseq:NP_001334988.1|refseq:NP_001334989.1|dip:DIP-34773N|dip:DIP-46290N|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007420"(brain development)|go:"GO:0008038"(neuron recognition)|go:"GO:0009615"(response to virus)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035690"|go:"GO:0038147"(C-X-C motif chemokine 12 receptor activity)|go:"GO:0038160"(CXCL12-activated CXCR4 signaling pathway)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR022726|mint:P61073|rcsb pdb:2K03|rcsb pdb:2K04|rcsb pdb:2K05|rcsb pdb:2N55|rcsb pdb:3ODU|rcsb pdb:3OE0|rcsb pdb:3OE6|rcsb pdb:3OE8|rcsb pdb:3OE9|rcsb pdb:4RWS|reactome:R-HSA-173107|reactome:R-HSA-376176|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0043217"(myelin maintenance)|go:"GO:0043278"(response to morphine)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050792"(regulation of viral process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|go:"GO:1990478"(response to ultrasound)|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR001277(C-X-C chemokine receptor, type 4)|ensembl:ENSG00000121966(gene)|ensembl:ENST00000241393(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|mint:MINT-7234502(identity) - - - figure legend:F1D|comment:homomint|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/07/30 2014/10/16 rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606 rogid:/DC0/+M1YsFLLfsDimppXSS/vpQ9606 intact-crc:D72A6CF78B27909C|rigid:XHAO1gQsHoUIJsU5v6DAYlpi5sc false yellow fluorescent protein tag:?-?(MINT-7234504) tag:?-?(MINT-7234508) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04233 uniprotkb:P61073 intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530 intact:EBI-489411|uniprotkb:Q53S69|uniprotkb:O60835|uniprotkb:P30991|uniprotkb:P56438|uniprotkb:Q9UKN2|uniprotkb:B2R5N0|uniprotkb:Q9BXA0|ensembl:ENSP00000241393 psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short) psi-mi:cxcr4_human(display_long)|uniprotkb:Stromal cell-derived factor 1 receptor(gene name synonym)|uniprotkb:Fusin(gene name synonym)|uniprotkb:Leukocyte-derived seven transmembrane domain receptor(gene name synonym)|uniprotkb:LCR1(gene name synonym)|uniprotkb:FB22(gene name synonym)|uniprotkb:NPYRL(gene name synonym)|uniprotkb:HM89(gene name synonym)|uniprotkb:CXCR4(gene name)|psi-mi:CXCR4(display_short)|uniprotkb:Lipopolysaccharide-associated protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Schwartz et al. (2009) pubmed:19665027|mint:MINT-7234485|mint:d-09-00737 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7156705|mint:MINT-7234512 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|mint:MINT-7234518(identity) refseq:NP_001008540.1|refseq:NP_003458.1|refseq:NP_001334985.1|refseq:NP_001334988.1|refseq:NP_001334989.1|dip:DIP-34773N|dip:DIP-46290N|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007420"(brain development)|go:"GO:0008038"(neuron recognition)|go:"GO:0009615"(response to virus)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035690"|go:"GO:0038147"(C-X-C motif chemokine 12 receptor activity)|go:"GO:0038160"(CXCL12-activated CXCR4 signaling pathway)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR022726|mint:P61073|rcsb pdb:2K03|rcsb pdb:2K04|rcsb pdb:2K05|rcsb pdb:2N55|rcsb pdb:3ODU|rcsb pdb:3OE0|rcsb pdb:3OE6|rcsb pdb:3OE8|rcsb pdb:3OE9|rcsb pdb:4RWS|reactome:R-HSA-173107|reactome:R-HSA-376176|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0043217"(myelin maintenance)|go:"GO:0043278"(response to morphine)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050792"(regulation of viral process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|go:"GO:1990478"(response to ultrasound)|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR001277(C-X-C chemokine receptor, type 4)|ensembl:ENSG00000121966(gene)|ensembl:ENST00000241393(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|mint:MINT-7234514(identity) - - - figure legend:F2A|comment:homomint|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/07/30 2014/10/16 rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606 rogid:/DC0/+M1YsFLLfsDimppXSS/vpQ9606 intact-crc:ED07E13A679B6EEF|rigid:XHAO1gQsHoUIJsU5v6DAYlpi5sc false v5 tag:?-?(MINT-7234519) ha tag:?-?(MINT-7234515) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P61073 uniprotkb:P04233 intact:EBI-489411|uniprotkb:Q53S69|uniprotkb:O60835|uniprotkb:P30991|uniprotkb:P56438|uniprotkb:Q9UKN2|uniprotkb:B2R5N0|uniprotkb:Q9BXA0|ensembl:ENSP00000241393 intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530 psi-mi:cxcr4_human(display_long)|uniprotkb:Stromal cell-derived factor 1 receptor(gene name synonym)|uniprotkb:Fusin(gene name synonym)|uniprotkb:Leukocyte-derived seven transmembrane domain receptor(gene name synonym)|uniprotkb:LCR1(gene name synonym)|uniprotkb:FB22(gene name synonym)|uniprotkb:NPYRL(gene name synonym)|uniprotkb:HM89(gene name synonym)|uniprotkb:CXCR4(gene name)|psi-mi:CXCR4(display_short)|uniprotkb:Lipopolysaccharide-associated protein 3(gene name synonym) psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Schwartz et al. (2009) pubmed:19665027|mint:MINT-7234485|mint:d-09-00737 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7156722|mint:MINT-7234528 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001008540.1|refseq:NP_003458.1|refseq:NP_001334985.1|refseq:NP_001334988.1|refseq:NP_001334989.1|dip:DIP-34773N|dip:DIP-46290N|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007420"(brain development)|go:"GO:0008038"(neuron recognition)|go:"GO:0009615"(response to virus)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035690"|go:"GO:0038147"(C-X-C motif chemokine 12 receptor activity)|go:"GO:0038160"(CXCL12-activated CXCR4 signaling pathway)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR022726|mint:P61073|rcsb pdb:2K03|rcsb pdb:2K04|rcsb pdb:2K05|rcsb pdb:2N55|rcsb pdb:3ODU|rcsb pdb:3OE0|rcsb pdb:3OE6|rcsb pdb:3OE8|rcsb pdb:3OE9|rcsb pdb:4RWS|reactome:R-HSA-173107|reactome:R-HSA-376176|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0043217"(myelin maintenance)|go:"GO:0043278"(response to morphine)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050792"(regulation of viral process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|go:"GO:1990478"(response to ultrasound)|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR001277(C-X-C chemokine receptor, type 4)|ensembl:ENSG00000121966(gene)|ensembl:ENST00000241393(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|mint:MINT-7234534(identity) refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|mint:MINT-7234530(identity) - - - figure legend:F2B F2C|comment:homomint|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/07/30 2014/10/16 rogid:/DC0/+M1YsFLLfsDimppXSS/vpQ9606 rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606 intact-crc:D7FC9CC58C4317FC|rigid:XHAO1gQsHoUIJsU5v6DAYlpi5sc false ha tag:?-?(MINT-7234535) v5 tag:?-?(MINT-7234531) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P61073 uniprotkb:P04233 intact:EBI-489411|uniprotkb:Q53S69|uniprotkb:O60835|uniprotkb:P30991|uniprotkb:P56438|uniprotkb:Q9UKN2|uniprotkb:B2R5N0|uniprotkb:Q9BXA0|ensembl:ENSP00000241393 intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530 psi-mi:cxcr4_human(display_long)|uniprotkb:Stromal cell-derived factor 1 receptor(gene name synonym)|uniprotkb:Fusin(gene name synonym)|uniprotkb:Leukocyte-derived seven transmembrane domain receptor(gene name synonym)|uniprotkb:LCR1(gene name synonym)|uniprotkb:FB22(gene name synonym)|uniprotkb:NPYRL(gene name synonym)|uniprotkb:HM89(gene name synonym)|uniprotkb:CXCR4(gene name)|psi-mi:CXCR4(display_short)|uniprotkb:Lipopolysaccharide-associated protein 3(gene name synonym) psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schwartz et al. (2009) pubmed:19665027|mint:MINT-7234485|mint:d-09-00737 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7156767|mint:MINT-7234542 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001008540.1|refseq:NP_003458.1|refseq:NP_001334985.1|refseq:NP_001334988.1|refseq:NP_001334989.1|dip:DIP-34773N|dip:DIP-46290N|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007420"(brain development)|go:"GO:0008038"(neuron recognition)|go:"GO:0009615"(response to virus)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035690"|go:"GO:0038147"(C-X-C motif chemokine 12 receptor activity)|go:"GO:0038160"(CXCL12-activated CXCR4 signaling pathway)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR022726|mint:P61073|rcsb pdb:2K03|rcsb pdb:2K04|rcsb pdb:2K05|rcsb pdb:2N55|rcsb pdb:3ODU|rcsb pdb:3OE0|rcsb pdb:3OE6|rcsb pdb:3OE8|rcsb pdb:3OE9|rcsb pdb:4RWS|reactome:R-HSA-173107|reactome:R-HSA-376176|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0043217"(myelin maintenance)|go:"GO:0043278"(response to morphine)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050792"(regulation of viral process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|go:"GO:1990478"(response to ultrasound)|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR001277(C-X-C chemokine receptor, type 4)|ensembl:ENSG00000121966(gene)|ensembl:ENST00000241393(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|mint:MINT-7234544(identity) refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|mint:MINT-7234548(identity) - - - figure legend:F3C|comment:homomint|comment:mint taxid:9606(human-mm6)|taxid:9606(Human-Mono Mac 6 monoblastic leukemic cell line) - 2009/07/30 2014/10/16 rogid:/DC0/+M1YsFLLfsDimppXSS/vpQ9606 rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606 intact-crc:A209F61C27229339|rigid:XHAO1gQsHoUIJsU5v6DAYlpi5sc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)