#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q13829	uniprotkb:P62745	intact:EBI-2505861|uniprotkb:B7Z6M4|uniprotkb:Q5TZQ1|ensembl:ENSP00000226225	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	psi-mi:bacd2_human(display_long)|uniprotkb:BACURD2(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein TNFAIP1(gene name synonym)|uniprotkb:Protein B12(gene name synonym)|uniprotkb:TNFAIP1(gene name)|psi-mi:TNFAIP1(display_short)|uniprotkb:EDP1(gene name synonym)|uniprotkb:Tumor necrosis factor, alpha-induced protein 1, endothelial(gene name synonym)	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2505880|imex:IM-20406-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066960.1|ensembl:ENSG00000109079(gene)|ensembl:ENST00000226225(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030332"(cyclin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q13829|reactome:R-HSA-9696264|reactome:R-HSA-9696270	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/03	2014/10/16	rogid:8vM9HnNmkirDbJRETV/TeE8pONY9606	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	intact-crc:993D6C8848CEF192|rigid:cd3z7YyB61elQOLXkuHjd72r3jg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62745	uniprotkb:Q9H3F6	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	intact:EBI-2505886|uniprotkb:Q53HN2|uniprotkb:Q59FV1|uniprotkb:Q6PL47|uniprotkb:Q96SU0|intact:EBI-2563423|ensembl:ENSP00000228495	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:bacd3_human(display_long)|uniprotkb:BTB/POZ domain-containing protein KCTD10(gene name synonym)|uniprotkb:Potassium channel tetramerization domain-containing protein 10(gene name synonym)|uniprotkb:KCTD10(gene name)|psi-mi:KCTD10(display_short)|uniprotkb:ULR061(gene name synonym)|uniprotkb:MSTP028(orf name)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2505922|imex:IM-20406-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	refseq:NP_001304324.1|refseq:NP_001304328.1|refseq:NP_114160.1|ensembl:ENSG00000110906(gene)|ensembl:ENST00000228495(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|rcsb pdb:5FTA	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/03	2014/10/16	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	rogid:ol+Pl17F/3aoKl1CD+edgT9KweI9606	intact-crc:665EFD2F7ACDB94B|rigid:efziHxgwI+NTDo9umM0RYRUKtSE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62745	uniprotkb:P51955	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	intact:EBI-633182|uniprotkb:Q53FD6|uniprotkb:Q5VXZ1|intact:EBI-4311380|uniprotkb:Q5I1Z9|uniprotkb:Q6NZX8|uniprotkb:Q7Z634|uniprotkb:Q86XH2|uniprotkb:Q96QN9|ensembl:ENSP00000355966	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:nek2_human(display_long)|uniprotkb:NEK2A(gene name synonym)|uniprotkb:NimA-like protein kinase 1(gene name synonym)|uniprotkb:HSPK 21(gene name synonym)|uniprotkb:NEK2(gene name)|psi-mi:NEK2(display_short)|uniprotkb:NLK1(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2505924|imex:IM-20406-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	refseq:NP_001191111.1|refseq:NP_001191112.1|refseq:NP_002488.1|ensembl:ENSG00000117650(gene)|ensembl:ENST00000366999(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001824"(blastocyst development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030496"(midbody)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051299"(centrosome separation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903126"(negative regulation of centriole-centriole cohesion)|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:P51955|rcsb pdb:2JAV|rcsb pdb:2W5A|rcsb pdb:2W5B|rcsb pdb:2W5H|rcsb pdb:2WQO|rcsb pdb:2XK3|rcsb pdb:2XK4|rcsb pdb:2XK6|rcsb pdb:2XK7|rcsb pdb:2XK8|rcsb pdb:2XKC|rcsb pdb:2XKD|rcsb pdb:2XKE|rcsb pdb:2XKF|rcsb pdb:2XNM|rcsb pdb:2XNN|rcsb pdb:2XNO|rcsb pdb:2XNP|rcsb pdb:4A4X|rcsb pdb:4AFE|rcsb pdb:5M51|rcsb pdb:5M53|rcsb pdb:5M55|rcsb pdb:5M57|rcsb pdb:6SGD|rcsb pdb:6SGH|rcsb pdb:6SGI|rcsb pdb:6SGK|rcsb pdb:6SK9|rcsb pdb:6TM5|reactome:R-HSA-179409|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_005273204.1	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/03	2014/10/16	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	rogid:7iozc82+IF+sGyerzvp571Uc1RM9606	intact-crc:95551F1A748986B8|rigid:WO4VJZMGpj/URTt3iWOVBjbGsBs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22392	uniprotkb:P62745	intact:EBI-713693|ensembl:ENSP00000376886|ensembl:ENSP00000421064|ensembl:ENSP00000425581|ensembl:ENSP00000426901|ensembl:ENSP00000426976|uniprotkb:A8MWA3|uniprotkb:Q1WM23|uniprotkb:Q6LCT6	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	psi-mi:ndkb_human(display_long)|uniprotkb:nm23-H2(gene name synonym)|uniprotkb:C-myc purine-binding transcription factor PUF(gene name synonym)|uniprotkb:NME2(gene name)|psi-mi:NME2(display_short)|uniprotkb:NM23B(gene name synonym)|uniprotkb:Histidine protein kinase NDKB(gene name synonym)	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2505928|imex:IM-20406-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000243678(gene)|ensembl:ENST00000393190(transcript)|ensembl:ENST00000503064(transcript)|ensembl:ENST00000512737(transcript)|ensembl:ENST00000513177(transcript)|ensembl:ENST00000514264(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_001018146.1|refseq:NP_001018147.1|refseq:NP_001018148.1|refseq:NP_001018149.1|refseq:NP_002503.1|dip:DIP-50179N|go:"GO:0005882"(intermediate filament)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0060416"(response to growth hormone)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071944"(cell periphery)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:P22392|rcsb pdb:1NSK|rcsb pdb:1NUE|rcsb pdb:3BBB|rcsb pdb:3BBC|rcsb pdb:3BBF|reactome:R-HSA-499943|reactome:R-HSA-6798695|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019003"(GDP binding)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/03	2014/10/16	rogid:GHHfoXOuc25KIJJqiW9r+OWm5Kk9606	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	intact-crc:1D1857F5AF767FE1|rigid:FPWyu7Q29hhhrXWYLf2LVgw/AlY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62745	uniprotkb:Q9UHV2	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2505931|imex:IM-20406-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	refseq:NP_037508.2|ensembl:ENSG00000197019(gene)|ensembl:ENST00000357949(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9UHV2	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/03	2014/10/16	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	rogid:40dvjniwxY/UQiyoVREicctpWe09606	intact-crc:62CFCC3A93EC6A53|rigid:mNEF/HIfBbTTxKxY/JlIRYdEVsY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35555	uniprotkb:P62745	intact:EBI-2505934|ensembl:ENSP00000325527|uniprotkb:B2RUU0|uniprotkb:Q15972|uniprotkb:Q75N87|uniprotkb:D2JYH6	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	psi-mi:fbn1_human(display_long)|uniprotkb:FBN1(gene name)|psi-mi:FBN1(display_short)|uniprotkb:FBN(gene name synonym)	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2505979|imex:IM-20406-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166147(gene)|ensembl:ENST00000316623(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001527"(microfibril)|go:"GO:0001656"(metanephros development)|go:"GO:0005178"(integrin binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0008201"(heparin binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030023"(extracellular matrix constituent conferring elasticity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034199"(activation of protein kinase A activity)|go:"GO:0035582"(sequestering of BMP in extracellular matrix)|go:"GO:0035583"(sequestering of TGFbeta in extracellular matrix)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048050"(post-embryonic eye morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:2001205"(negative regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011398(Fibrillin)|interpro:IPR017878|interpro:IPR018097|interpro:IPR026823|interpro:IPR036773|interpro:IPR040872|mint:P35555|rcsb pdb:1APJ|rcsb pdb:1EMN|rcsb pdb:1EMO|rcsb pdb:1LMJ|rcsb pdb:1UZJ|rcsb pdb:1UZK|rcsb pdb:1UZP|rcsb pdb:1UZQ|rcsb pdb:2M74|rcsb pdb:2W86|rcsb pdb:5MS9|reactome:R-HSA-1474228|reactome:R-HSA-1566948|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_000129.3|dip:DIP-29985N	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/03	2019/04/15	rogid:YEO0ZRTezrjEAyTaos1pm2hUDXg9606	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	intact-crc:7B0BE2931F9BB024|rigid:7T3Jdns5rn/VFAiSUdjK0c0ogag	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62745	uniprotkb:O43175	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	intact:EBI-350495|uniprotkb:Q5SZU3|uniprotkb:Q9BQ01|ensembl:ENSP00000493175|ensembl:ENSP00000493382|uniprotkb:B2RD08	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:sera_human(display_long)|uniprotkb:PHGDH(gene name)|psi-mi:PHGDH(display_short)|uniprotkb:PGDH3(gene name synonym)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:Malate dehydrogenase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2505982|imex:IM-20406-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	refseq:NP_006614.2|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070314"(G1 to G0 transition)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR006236(D-3-phosphoglycerate dehydrogenase)|interpro:IPR029009|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|mint:O43175|rcsb pdb:2G76|rcsb pdb:5N53|rcsb pdb:5N6C|rcsb pdb:5NZO|rcsb pdb:5NZP|rcsb pdb:5NZQ|rcsb pdb:5OFM|rcsb pdb:5OFV|ensembl:ENSG00000092621(gene)|ensembl:ENST00000641023(transcript)|ensembl:ENST00000641597(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006566"(threonine metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009448"(gamma-aminobutyric acid metabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0021510"(spinal cord development)|go:"GO:0021782"(glial cell development)|go:"GO:0021915"(neural tube development)|rcsb pdb:5OFW|rcsb pdb:6CWA|rcsb pdb:6PLF|rcsb pdb:6PLG|rcsb pdb:6RIH|rcsb pdb:6RJ2|rcsb pdb:6RJ3|rcsb pdb:6RJ5|rcsb pdb:6RJ6|rcsb pdb:7CVP|reactome:R-HSA-977347	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/03	2014/10/16	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	rogid:uzg4EVysd7/zLXBurqwTCFMvqiA9606	intact-crc:B65E7D96BDC07D72|rigid:17nTIc7XDaXUvB/9hEaciokWPWY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P16083	uniprotkb:P62745	intact:EBI-358466|uniprotkb:B2R492|ensembl:ENSP00000337773|ensembl:ENSP00000369795|ensembl:ENSP00000369822|uniprotkb:Q5TD04	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	psi-mi:nqo2_human(display_long)|uniprotkb:NQO2(gene name)|psi-mi:NQO2(display_short)|uniprotkb:NMOR2(gene name synonym)|uniprotkb:NRH dehydrogenase [quinone] 2(gene name synonym)|uniprotkb:"NRH:quinone oxidoreductase 2"(gene name synonym)|uniprotkb:Quinone reductase 2(gene name synonym)	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2505993|imex:IM-20406-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1QR2|rcsb pdb:1SG0|go:"GO:0031404"(chloride ion binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071949"(FAD binding)|go:"GO:1901662"(quinone catabolic process)|go:"GO:1904408"(melatonin binding)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905594"(resveratrol binding)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003680(Flavodoxin-like fold)|interpro:IPR029039|refseq:NP_000895.2|ensembl:ENSG00000124588(gene)|ensembl:ENST00000338130(transcript)|ensembl:ENST00000380430(transcript)|ensembl:ENST00000380455(transcript)|go:"GO:0001512"(dihydronicotinamide riboside quinone reductase activity)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016661"(oxidoreductase activity, acting on other nitrogenous compounds as donors)|refseq:NP_001305869.1|refseq:NP_001277150.1|rcsb pdb:1XI2|rcsb pdb:1ZX1|rcsb pdb:2BZS|rcsb pdb:2QMY|rcsb pdb:2QMZ|rcsb pdb:2QR2|rcsb pdb:2QWX|rcsb pdb:2QX4|rcsb pdb:2QX6|rcsb pdb:2QX8|rcsb pdb:2QX9|rcsb pdb:3FW1|rcsb pdb:3G5M|rcsb pdb:3GAM|rcsb pdb:3NFR|rcsb pdb:3NHF|rcsb pdb:3NHJ|rcsb pdb:3NHK|rcsb pdb:3NHL|rcsb pdb:3NHP|rcsb pdb:3NHR|rcsb pdb:3NHS|rcsb pdb:3NHW|rcsb pdb:3NHY|rcsb pdb:3O2N|rcsb pdb:3O73|rcsb pdb:3OVM|rcsb pdb:3OWH|rcsb pdb:3OWX|rcsb pdb:3OX1|rcsb pdb:3OX2|rcsb pdb:3OX3|rcsb pdb:3TE7|rcsb pdb:3TEM|rcsb pdb:3TZB|rcsb pdb:3UXE|rcsb pdb:3UXH|rcsb pdb:4FGJ|rcsb pdb:4FGK|rcsb pdb:4FGL|rcsb pdb:4GQI|rcsb pdb:4GR9|rcsb pdb:4QOD|rcsb pdb:4QOE|rcsb pdb:4QOF|rcsb pdb:4QOG|rcsb pdb:4QOH|rcsb pdb:4QOI|rcsb pdb:4QOJ|rcsb pdb:4U7F|rcsb pdb:4U7G|rcsb pdb:4U7H|rcsb pdb:4XDG|rcsb pdb:4XDH|rcsb pdb:4ZVK|rcsb pdb:4ZVL|rcsb pdb:4ZVM|rcsb pdb:4ZVN|rcsb pdb:5BUC|rcsb pdb:5LBT|rcsb pdb:5LBU|rcsb pdb:5LBW|rcsb pdb:5LBY|rcsb pdb:5LBZ|reactome:R-HSA-211945|rcsb pdb:3NHU|dip:DIP-39704N	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/03	2014/10/16	rogid:e23niMWdj6fUH4WR3K6sUCTM0KE9606	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	intact-crc:696BD1CE1F999582|rigid:l+fR34Rvzhra0sL6BNZRfLbKyiE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5V2	uniprotkb:P62745	intact:EBI-718372|uniprotkb:B9A045|uniprotkb:Q53QQ4|uniprotkb:Q53ST7|uniprotkb:Q6GMQ5|uniprotkb:Q9NQD6|uniprotkb:B4DMB8|uniprotkb:E9PC42|ensembl:ENSP00000264051	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	psi-mi:ngef_human(display_long)|uniprotkb:Eph-interacting exchange protein(gene name synonym)|uniprotkb:Neuronal guanine nucleotide exchange factor(gene name synonym)|uniprotkb:NGEF(gene name)|psi-mi:NGEF(display_short)	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2505996|imex:IM-20406-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001107562.1|refseq:NP_062824.2|refseq:XP_011509225.1|ensembl:ENSG00000066248(gene)|ensembl:ENST00000264051(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030426"(growth cone)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035635|interpro:IPR035899|interpro:IPR036028|mint:Q8N5V2|reactome:R-HSA-193648|reactome:R-HSA-3928663|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|go:"GO:0005829"(cytosol)	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/03	2014/10/16	rogid:oAu+8njDslYpqxQaq85zzC3hb209606	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	intact-crc:FCA8F3EF2A34E8E3|rigid:YN9KdZoBTm6Gaulm7s//ipHb+P8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62745	uniprotkb:Q92888	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	intact:EBI-465400|uniprotkb:O00513|uniprotkb:Q8N4J4|uniprotkb:Q96BF4|uniprotkb:Q96F17|uniprotkb:Q9BSB1|uniprotkb:Q6NX52|ensembl:ENSP00000346532	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:arhg1_human(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short)|uniprotkb:115 kDa guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Sub1.5(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2505999|imex:IM-20406-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	refseq:NP_004697.2|refseq:NP_945328.1|refseq:NP_945353.1|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000076928(gene)|ensembl:ENST00000354532(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036305|interpro:IPR037887|interpro:IPR041020|mint:Q92888|rcsb pdb:1IAP|rcsb pdb:1SHZ|rcsb pdb:3AB3|rcsb pdb:3ODO|rcsb pdb:3ODW|rcsb pdb:3ODX|rcsb pdb:3P6A	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/03	2014/10/16	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	rogid:XIZmflM2cr80ZBD3FO21IDMnInE9606	intact-crc:A0A922219FD0A111|rigid:bCR0ltraFgbjYg4JCGzQwgMCcBA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52565	uniprotkb:P62745	intact:EBI-712693|intact:EBI-718039|ensembl:ENSP00000269321|ensembl:ENSP00000441348|ensembl:ENSP00000464205|intact:EBI-2840752|uniprotkb:A8MXW0|uniprotkb:B4DDD3|uniprotkb:B4DUV9|uniprotkb:B2R5X1|uniprotkb:Q6IBM5	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	psi-mi:gdir1_human(display_long)|uniprotkb:Rho-GDI alpha(gene name synonym)|uniprotkb:ARHGDIA(gene name)|psi-mi:ARHGDIA(display_short)|uniprotkb:GDIA1(gene name synonym)	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2506002|imex:IM-20406-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141522(gene)|ensembl:ENST00000269321(transcript)|ensembl:ENST00000541078(transcript)|ensembl:ENST00000580685(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0005094"(Rho GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071461"(cellular response to redox state)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52565|rcsb pdb:1CC0|rcsb pdb:1FSO|rcsb pdb:1FST|rcsb pdb:1FT0|rcsb pdb:1FT3|rcsb pdb:1HH4|rcsb pdb:1KMT|rcsb pdb:1QVY|rcsb pdb:1RHO|rcsb pdb:2BXW|rcsb pdb:2JHS|rcsb pdb:2JHT|rcsb pdb:2JHU|rcsb pdb:2JHV|rcsb pdb:2JHW|rcsb pdb:2JHX|rcsb pdb:2JHY|rcsb pdb:2JHZ|rcsb pdb:2JI0|rcsb pdb:2N80|reactome:R-HSA-193634|reactome:R-HSA-209563|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013407|reactome:R-HSA-9013408|go:"GO:0005634"(nucleus)|refseq:NP_001172006.1|refseq:NP_001172007.1|refseq:NP_004300.1|refseq:NP_001288169.1|refseq:NP_001288170.1|refseq:NP_001288171.1|refseq:NP_001288172.1	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/03	2014/10/16	rogid:nHmwosTUeo1R72Mp5uHLYdcBofk9606	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	intact-crc:84FEFAA42D5AED0F|rigid:adOJIYp0rW0fdKgU91fTeO1yyf8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62745	uniprotkb:P33316	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	intact:EBI-353224|uniprotkb:O14785|uniprotkb:Q16708|uniprotkb:Q16860|uniprotkb:Q96Q81|uniprotkb:A8K650|uniprotkb:B4DPR5|uniprotkb:Q6FHN1|uniprotkb:Q6NSA3|ensembl:ENSP00000370376	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:dut_human(display_long)|uniprotkb:DUT(gene name)|psi-mi:DUT(display_short)|uniprotkb:dUTP pyrophosphatase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2506006|imex:IM-20406-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	refseq:NP_001020419.1|refseq:NP_001020420.1|refseq:NP_001939.1|rcsb pdb:1Q5U|rcsb pdb:2HQU|rcsb pdb:3ARA|rcsb pdb:3ARN|rcsb pdb:3EHW|rcsb pdb:4MZ5|rcsb pdb:4MZ6|rcsb pdb:5H4J|reactome:R-HSA-499943|ensembl:ENSG00000128951(gene)|ensembl:ENST00000331200(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006260"(DNA replication)|go:"GO:0046081"(dUTP catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008181(DeoxyUTP pyrophosphatase subfamily 1)|interpro:IPR029054|interpro:IPR033704|interpro:IPR036157|rcsb pdb:1Q5H|refseq:NP_001317215.1	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/03	2014/10/16	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	rogid:lHET9Z1Rre4xbVStybz65KJ8QLk9606	intact-crc:326328A17D6FDCC1|rigid:gq9rPTZboUuQWcdPGd3zZFOBd+o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13427	uniprotkb:P62745	intact:EBI-396072|uniprotkb:O00706|uniprotkb:Q96DG9|uniprotkb:Q53R40|uniprotkb:Q53SN4|ensembl:ENSP00000260970|ensembl:ENSP00000407083|ensembl:ENSP00000408683|ensembl:ENSP00000502997|ensembl:ENSP00000503136|ensembl:ENSP00000503525|uniprotkb:D3DPC5|uniprotkb:D3DPC6	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	psi-mi:ppig_human(display_long)|uniprotkb:PPIG(gene name)|psi-mi:PPIG(display_short)|uniprotkb:Cyclophilin G(gene name synonym)|uniprotkb:Clk-associating RS-cyclophilin(gene name synonym)|uniprotkb:CASP10(gene name synonym)|uniprotkb:Rotamase G(gene name synonym)	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2506009|imex:IM-20406-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004783.2|ensembl:ENSG00000138398(gene)|ensembl:ENST00000260970(transcript)|ensembl:ENST00000433207(transcript)|ensembl:ENST00000448752(transcript)|ensembl:ENST00000676756(transcript)|ensembl:ENST00000678499(transcript)|ensembl:ENST00000679107(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:Q13427|rcsb pdb:2GW2|rcsb pdb:2WFI|rcsb pdb:2WFJ|rcsb pdb:5YZG|go:"GO:0006457"(protein folding)|refseq:XP_005247023.1|refseq:XP_005247024.1	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/03	2014/10/16	rogid:gp1Pqv5G8E+PrPmp+BtUSSIkD/89606	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	intact-crc:F37791E43A619B07|rigid:oXYerZkGKm+rPOo2YzbW861VqfY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60739	uniprotkb:P62745	intact:EBI-1043343|uniprotkb:Q9UQF8|ensembl:ENSP00000232905	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	psi-mi:eif1b_human(display_long)|uniprotkb:Protein translation factor SUI1 homolog GC20(gene name synonym)|uniprotkb:EIF1B(gene name)|psi-mi:EIF1B(display_short)	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2506060|imex:IM-20406-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114784(gene)|ensembl:ENST00000232905(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR001950(Translation initiation factor SUI1)|interpro:IPR005874(Eukaryotic translation initiation factor SUI1)|interpro:IPR036877|mint:O60739|refseq:NP_005866.1	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/03	2014/10/16	rogid:0nnqCaTD/q0KhGcITR0LD7WLET09606	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	intact-crc:6B5C5EF759D76FB5|rigid:0dhrYExs/2cUrUXCzgak7/uFwCQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60831	uniprotkb:P62745	intact:EBI-2506064|ensembl:ENSP00000451962|uniprotkb:B2RD20	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	psi-mi:praf2_human(display_long)|uniprotkb:PRAF2(gene name)|psi-mi:PRAF2(display_short)|uniprotkb:JM4(orf name)	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2506078|imex:IM-20406-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000243279(gene)|ensembl:ENST00000553851(transcript)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O60831|refseq:NP_009144.1	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/03	2014/10/16	rogid:ZCku1zr9TwPArrSO0aaKZlDsEyU9606	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	intact-crc:AEB7239D792833C0|rigid:aZLXLE7ojQTLjnuUCJCCG5GUMg0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6P3S6	uniprotkb:P62745	intact:EBI-2506081|ensembl:ENSP00000364742|uniprotkb:B3KP30|uniprotkb:Q5TEU8|uniprotkb:Q86XI0|uniprotkb:Q8N3N4|uniprotkb:Q8N5F8|uniprotkb:Q9BRM0|uniprotkb:Q9P2L4	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	psi-mi:fbx42_human(display_long)|uniprotkb:FBXO42(gene name)|psi-mi:FBXO42(display_short)|uniprotkb:FBX42(gene name synonym)|uniprotkb:JFK(gene name synonym)|uniprotkb:KIAA1332(gene name synonym)|uniprotkb:Just one F-box and Kelch domain-containing protein(gene name synonym)	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2506105|imex:IM-20406-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000037637(gene)|ensembl:ENST00000375592(transcript)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036047|refseq:NP_061867.1|refseq:XP_006710761.1	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/03	2014/10/16	rogid:agCUwHKc4LmiE/1IrJsxJQNgUVo9606	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	intact-crc:C16CC0BD94C8D737|rigid:snGANMJcvGX/QPGy/f5IV9WKDmw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62745	uniprotkb:P78559	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	intact:EBI-929047|uniprotkb:O95643|uniprotkb:Q12973|uniprotkb:Q15882|uniprotkb:Q9UJT4|ensembl:ENSP00000300231	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:map1a_human(display_long)|uniprotkb:MAP1A(gene name)|psi-mi:MAP1A(display_short)|uniprotkb:Proliferation-related protein p80(gene name synonym)|uniprotkb:MAP1L(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2506108|imex:IM-20406-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	ensembl:ENSP00000300231|refseq:NP_002364.5|dip:DIP-36377N|ensembl:ENSG00000166963(gene)|ensembl:ENST00000300231(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007409"(axonogenesis)|go:"GO:0007613"(memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008306"(associative learning)|go:"GO:0015631"(tubulin binding)|go:"GO:0016358"(dendrite development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044307"(dendritic branch)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0150001"(primary dendrite)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1902817"(negative regulation of protein localization to microtubule)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR015656(MAP1A)|interpro:IPR026074|interpro:IPR036866|mint:P78559	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/03	2014/10/16	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	rogid:lj3f+wL17n1HzPdo9c+15/9Uv0o9606	intact-crc:7C0901DB0BF2D1EB|rigid:KHnqRM10h7bP8TTgelqzg2yJoXA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62745	uniprotkb:Q13829	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	intact:EBI-2505861|uniprotkb:B7Z6M4|uniprotkb:Q5TZQ1|ensembl:ENSP00000226225	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:bacd2_human(display_long)|uniprotkb:BACURD2(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein TNFAIP1(gene name synonym)|uniprotkb:Protein B12(gene name synonym)|uniprotkb:TNFAIP1(gene name)|psi-mi:TNFAIP1(display_short)|uniprotkb:EDP1(gene name synonym)|uniprotkb:Tumor necrosis factor, alpha-induced protein 1, endothelial(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2506119|imex:IM-20406-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	refseq:NP_066960.1|ensembl:ENSG00000109079(gene)|ensembl:ENST00000226225(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030332"(cyclin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q13829|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Fig. 2b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2009/12/03	2014/10/16	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	rogid:8vM9HnNmkirDbJRETV/TeE8pONY9606	intact-crc:92F34AB0263873F8|rigid:cd3z7YyB61elQOLXkuHjd72r3jg	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P62745	uniprotkb:Q13829	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	intact:EBI-2505861|uniprotkb:B7Z6M4|uniprotkb:Q5TZQ1|ensembl:ENSP00000226225	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:bacd2_human(display_long)|uniprotkb:BACURD2(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein TNFAIP1(gene name synonym)|uniprotkb:Protein B12(gene name synonym)|uniprotkb:TNFAIP1(gene name)|psi-mi:TNFAIP1(display_short)|uniprotkb:EDP1(gene name synonym)|uniprotkb:Tumor necrosis factor, alpha-induced protein 1, endothelial(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2506140|imex:IM-20406-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	refseq:NP_066960.1|ensembl:ENSG00000109079(gene)|ensembl:ENST00000226225(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030332"(cyclin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q13829|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Fig. 2c|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/12/03	2014/10/16	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	rogid:8vM9HnNmkirDbJRETV/TeE8pONY9606	intact-crc:776AC89D188059C5|rigid:cd3z7YyB61elQOLXkuHjd72r3jg	false	glutathione s tranferase tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P62745	uniprotkb:Q13829	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	intact:EBI-2505861|uniprotkb:B7Z6M4|uniprotkb:Q5TZQ1|ensembl:ENSP00000226225	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:bacd2_human(display_long)|uniprotkb:BACURD2(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein TNFAIP1(gene name synonym)|uniprotkb:Protein B12(gene name synonym)|uniprotkb:TNFAIP1(gene name)|psi-mi:TNFAIP1(display_short)|uniprotkb:EDP1(gene name synonym)|uniprotkb:Tumor necrosis factor, alpha-induced protein 1, endothelial(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2506166|imex:IM-20406-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	refseq:NP_066960.1|ensembl:ENSG00000109079(gene)|ensembl:ENST00000226225(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030332"(cyclin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q13829|reactome:R-HSA-9696264|reactome:R-HSA-9696270	go:"GO:0005768"(endosome)	-	-	figure legend:Fig. 2d a, b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells)	-	2009/12/03	2014/10/16	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	rogid:8vM9HnNmkirDbJRETV/TeE8pONY9606	intact-crc:CA42AFC3645B3F66|rigid:cd3z7YyB61elQOLXkuHjd72r3jg	false	green fluorescent protein tag:?-?	red fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q13829	uniprotkb:P62745	intact:EBI-2505861|uniprotkb:B7Z6M4|uniprotkb:Q5TZQ1|ensembl:ENSP00000226225	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233	psi-mi:bacd2_human(display_long)|uniprotkb:BACURD2(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein TNFAIP1(gene name synonym)|uniprotkb:Protein B12(gene name synonym)|uniprotkb:TNFAIP1(gene name)|psi-mi:TNFAIP1(display_short)|uniprotkb:EDP1(gene name synonym)|uniprotkb:Tumor necrosis factor, alpha-induced protein 1, endothelial(gene name synonym)	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2009)	pubmed:19637314|imex:IM-20406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2506593|imex:IM-20406-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066960.1|ensembl:ENSG00000109079(gene)|ensembl:ENST00000226225(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030332"(cyclin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q13829|reactome:R-HSA-9696264|reactome:R-HSA-9696270	refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type)	-	-	-	figure legend:Fig. 2a|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/03	2014/10/16	rogid:8vM9HnNmkirDbJRETV/TeE8pONY9606	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	intact-crc:5EAC973F4A33D5F3|rigid:cd3z7YyB61elQOLXkuHjd72r3jg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)