#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q13535	uniprotkb:Q99459	intact:EBI-968983|ensembl:ENSP00000343741|uniprotkb:Q7KYL3|uniprotkb:Q93051|uniprotkb:Q9BXK4|uniprotkb:Q59HB2	intact:EBI-374880|uniprotkb:Q76N46|uniprotkb:Q99974|ensembl:ENSP00000360532	psi-mi:atr_human(display_long)|uniprotkb:ATR(gene name)|psi-mi:ATR(display_short)|uniprotkb:FRP1(gene name synonym)|uniprotkb:Ataxia telangiectasia and Rad3-related protein(gene name synonym)|uniprotkb:FRAP-related protein 1(gene name synonym)	psi-mi:cdc5l_human(display_long)|uniprotkb:CDC5L(gene name)|psi-mi:CDC5L(display_short)|uniprotkb:Pombe cdc5-related protein(gene name synonym)|uniprotkb:KIAA0432(gene name synonym)|uniprotkb:PCDC5RP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Zhang et al. (2009)	pubmed:19633697|imex:IM-13926|mint:MINT-7262047|doi:10.1038/embor.2009.122	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7136244|mint:MINT-7262059|imex:IM-13926-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000175054(gene)|ensembl:ENST00000350721(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031297"(replication fork processing)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042493"|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090399"(replicative senescence)|go:"GO:0097694"(establishment of RNA localization to telomere)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1904884"(positive regulation of telomerase catalytic core complex assembly)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012993(UME)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR021133|interpro:IPR036940|mint:Q13535|rcsb pdb:5YZ0|reactome:R-HSA-1221632|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6783310|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:NP_001175.2|refseq:XP_016862132.1|dip:DIP-35308N|mint:MINT-7262062(identity)	go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|rcsb pdb:6ID1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071352"(cellular response to interleukin-2)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904568"(cellular response to wortmannin)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990646"(cellular response to prolactin)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|mint:Q99459|rcsb pdb:2DIM|rcsb pdb:2DIN|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|ensembl:ENSG00000096401(gene)|ensembl:ENST00000371477(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|refseq:NP_001244.1|dip:DIP-31731N|mint:MINT-7262061(identity)	-	-	-	figure legend:F1A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2009/09/07	2014/10/16	rogid:ZYzDNmnxcK+RJN42KfgQZlxGACU9606	rogid:ZNRraJHn//46wKLSx7xtZju/lr09606	intact-crc:8104DA162E6F52E6|rigid:CIjVY9+n3e7g9Jas94SnKJtGZQs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q99459	uniprotkb:Q13535	intact:EBI-374880|uniprotkb:Q76N46|uniprotkb:Q99974|ensembl:ENSP00000360532	intact:EBI-968983|ensembl:ENSP00000343741|uniprotkb:Q7KYL3|uniprotkb:Q93051|uniprotkb:Q9BXK4|uniprotkb:Q59HB2	psi-mi:cdc5l_human(display_long)|uniprotkb:CDC5L(gene name)|psi-mi:CDC5L(display_short)|uniprotkb:Pombe cdc5-related protein(gene name synonym)|uniprotkb:KIAA0432(gene name synonym)|uniprotkb:PCDC5RP(gene name synonym)	psi-mi:atr_human(display_long)|uniprotkb:ATR(gene name)|psi-mi:ATR(display_short)|uniprotkb:FRP1(gene name synonym)|uniprotkb:Ataxia telangiectasia and Rad3-related protein(gene name synonym)|uniprotkb:FRAP-related protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Zhang et al. (2009)	pubmed:19633697|imex:IM-13926|mint:MINT-7262047|doi:10.1038/embor.2009.122	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7136271|mint:MINT-7262068|imex:IM-13926-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|rcsb pdb:6ID1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071352"(cellular response to interleukin-2)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904568"(cellular response to wortmannin)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990646"(cellular response to prolactin)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|mint:Q99459|rcsb pdb:2DIM|rcsb pdb:2DIN|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|ensembl:ENSG00000096401(gene)|ensembl:ENST00000371477(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|refseq:NP_001244.1|dip:DIP-31731N|mint:MINT-7262072(identity)	ensembl:ENSG00000175054(gene)|ensembl:ENST00000350721(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031297"(replication fork processing)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042493"|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090399"(replicative senescence)|go:"GO:0097694"(establishment of RNA localization to telomere)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1904884"(positive regulation of telomerase catalytic core complex assembly)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012993(UME)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR021133|interpro:IPR036940|mint:Q13535|rcsb pdb:5YZ0|reactome:R-HSA-1221632|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6783310|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:NP_001175.2|refseq:XP_016862132.1|dip:DIP-35308N|mint:MINT-7262070(identity)	-	-	-	figure legend:F1A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2009/09/07	2014/10/16	rogid:ZNRraJHn//46wKLSx7xtZju/lr09606	rogid:ZYzDNmnxcK+RJN42KfgQZlxGACU9606	intact-crc:08ACE8AC9DF41826|rigid:CIjVY9+n3e7g9Jas94SnKJtGZQs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q99459	uniprotkb:Q13535	intact:EBI-374880|uniprotkb:Q76N46|uniprotkb:Q99974|ensembl:ENSP00000360532	intact:EBI-968983|ensembl:ENSP00000343741|uniprotkb:Q7KYL3|uniprotkb:Q93051|uniprotkb:Q9BXK4|uniprotkb:Q59HB2	psi-mi:cdc5l_human(display_long)|uniprotkb:CDC5L(gene name)|psi-mi:CDC5L(display_short)|uniprotkb:Pombe cdc5-related protein(gene name synonym)|uniprotkb:KIAA0432(gene name synonym)|uniprotkb:PCDC5RP(gene name synonym)	psi-mi:atr_human(display_long)|uniprotkb:ATR(gene name)|psi-mi:ATR(display_short)|uniprotkb:FRP1(gene name synonym)|uniprotkb:Ataxia telangiectasia and Rad3-related protein(gene name synonym)|uniprotkb:FRAP-related protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Zhang et al. (2009)	pubmed:19633697|imex:IM-13926|mint:MINT-7262047|doi:10.1038/embor.2009.122	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7136313|mint:MINT-7262077|imex:IM-13926-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|rcsb pdb:6ID1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071352"(cellular response to interleukin-2)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904568"(cellular response to wortmannin)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990646"(cellular response to prolactin)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|mint:Q99459|rcsb pdb:2DIM|rcsb pdb:2DIN|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|ensembl:ENSG00000096401(gene)|ensembl:ENST00000371477(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|refseq:NP_001244.1|dip:DIP-31731N|mint:MINT-7262079(identity)	ensembl:ENSG00000175054(gene)|ensembl:ENST00000350721(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031297"(replication fork processing)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042493"|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090399"(replicative senescence)|go:"GO:0097694"(establishment of RNA localization to telomere)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1904884"(positive regulation of telomerase catalytic core complex assembly)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012993(UME)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR021133|interpro:IPR036940|mint:Q13535|rcsb pdb:5YZ0|reactome:R-HSA-1221632|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6783310|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:NP_001175.2|refseq:XP_016862132.1|dip:DIP-35308N|mint:MINT-7262081(identity)	-	-	-	comment:homomint|comment:mint|figure legend:F1B F4B F4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/09/07	2014/10/16	rogid:ZNRraJHn//46wKLSx7xtZju/lr09606	rogid:ZYzDNmnxcK+RJN42KfgQZlxGACU9606	intact-crc:70DCEF8EB6ABAFB1|rigid:CIjVY9+n3e7g9Jas94SnKJtGZQs	false	glutathione s tranferase tag:?-?(MINT-7262090)|binding-associated region:180-251(MINT-7262092)	flag tag:?-?(MINT-7262087)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q99459	uniprotkb:Q9UMS4	intact:EBI-374880|uniprotkb:Q76N46|uniprotkb:Q99974|ensembl:ENSP00000360532	intact:EBI-395746|ensembl:ENSP00000227524	psi-mi:cdc5l_human(display_long)|uniprotkb:CDC5L(gene name)|psi-mi:CDC5L(display_short)|uniprotkb:Pombe cdc5-related protein(gene name synonym)|uniprotkb:KIAA0432(gene name synonym)|uniprotkb:PCDC5RP(gene name synonym)	psi-mi:prp19_human(display_long)|uniprotkb:PRPF19(gene name)|psi-mi:PRPF19(display_short)|uniprotkb:PRP19/PSO4 homolog(gene name synonym)|uniprotkb:Nuclear matrix protein 200(gene name synonym)|uniprotkb:Senescence evasion factor(gene name synonym)|uniprotkb:NMP200(gene name synonym)|uniprotkb:PRP19(gene name synonym)|uniprotkb:SNEV(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)	psi-mi:"MI:0096"(pull down)	Zhang et al. (2009)	pubmed:19633697|imex:IM-13926|mint:MINT-7262047|doi:10.1038/embor.2009.122	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7136412|mint:MINT-7262095|imex:IM-13926-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|rcsb pdb:6ID1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071352"(cellular response to interleukin-2)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904568"(cellular response to wortmannin)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990646"(cellular response to prolactin)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|mint:Q99459|rcsb pdb:2DIM|rcsb pdb:2DIN|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|ensembl:ENSG00000096401(gene)|ensembl:ENST00000371477(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|refseq:NP_001244.1|dip:DIP-31731N|mint:MINT-7262101(identity)	ensembl:ENSG00000110107(gene)|ensembl:ENST00000227524(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005819"(spindle)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|refseq:NP_055317.1|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001680(WD40 repeat)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR038959|mint:Q9UMS4|rcsb pdb:4LG8|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|dip:DIP-32978N|mint:MINT-7262097(identity)	-	-	-	figure legend:SF4|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2009/09/07	2014/10/16	rogid:ZNRraJHn//46wKLSx7xtZju/lr09606	rogid:5TseaFcCOVVWjJeMF/H7k29nd3c9606	intact-crc:D75A2B1B97927B6E|rigid:04RGFw/FnMbC/74SnNu0jr08F2g	false	glutathione s tranferase tag:?-?(MINT-7262104)	flag tag:?-?(MINT-7262098)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)