#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q11094 uniprotkb:G5EEG9 intact:EBI-2408513|uniprotkb:O76255|ensemblmetazoa:C02B8.4.1 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 psi-mi:twist_caeel(display_long)|uniprotkb:hlh-8(gene name)|psi-mi:hlh-8(display_short)|uniprotkb:CeTwist(gene name synonym)|uniprotkb:Helix-loop-helix protein 8(gene name synonym)|uniprotkb:C02B8.4(orf name) psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2408510|imex:IM-12203-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509367.1|wormbase:C02B8.4|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015789(Twist)|interpro:IPR036638|ensemblmetazoa:C02B8.4.1(transcript)|ensemblmetazoa:WBGene00001953(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0032502"(developmental process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0072327"(vulval cell fate specification) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:SmDeYwVWHbIAP3B+lBN1AKZ6Xlg6239 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 intact-crc:A467CC123168465C|rigid:Sx6A+uWiBmzwZrCupeni7lueC2M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EEG9 uniprotkb:Q23579 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 intact:EBI-2408537|ensemblmetazoa:ZK682.4.1 psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:hlh10_caeel(display_long)|uniprotkb:hlh-10(gene name)|psi-mi:hlh-10(display_short)|uniprotkb:CeABF-1(gene name synonym)|uniprotkb:ZK682.4(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2408550|imex:IM-12203-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) refseq:NP_505401.2|wormbase:ZK682.4|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:WBGene00001954(gene)|ensemblmetazoa:ZK682.4.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032502"(developmental process)|go:"GO:0046982"(protein heterodimerization activity) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 rogid:O+GVIebahoAQhMXajlJky1OvjMg6239 intact-crc:88624BB6B2952700|rigid:iXCfXFg6RdXQQtKKAZ/DsZ35m4o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EEG9 uniprotkb:Q20561 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 intact:EBI-2408554|ensemblmetazoa:F48D6.3.1 psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:hlh13_caeel(display_long)|uniprotkb:hlh-13(gene name)|psi-mi:hlh-13(display_short)|uniprotkb:cnato3(gene name synonym)|uniprotkb:ferd-3l(gene name synonym)|uniprotkb:Nephew of atonal 3(gene name synonym)|uniprotkb:Fer3-like protein(gene name synonym)|uniprotkb:F48D6.3(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2408575|imex:IM-12203-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) refseq:NP_508725.1|wormbase:F48D6.3|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:F48D6.3.1(transcript)|ensemblmetazoa:WBGene00001957(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032502"(developmental process)|go:"GO:0043054"(dauer exit)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0140297"(DNA-binding transcription factor binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 rogid:I9gZm44FWbjyw7sWcnKAeydPguA6239 intact-crc:7E8A39EEE5D79BE8|rigid:aVIRmELyDAGWa2HtIG2mYA5WthE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q09961 uniprotkb:G5EEG9 intact:EBI-2408579|ensemblmetazoa:C18A3.8.1 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 psi-mi:hlh14_caeel(display_long)|uniprotkb:hlh-14(gene name)|psi-mi:hlh-14(display_short)|uniprotkb:C18A3.8(orf name) psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2408595|imex:IM-12203-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495131.3|wormbase:C18A3.8|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:C18A3.8.1(transcript)|ensemblmetazoa:WBGene00001958(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0018991"(oviposition)|go:"GO:0040010"(positive regulation of growth rate)|go:"GO:0040011"(locomotion)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2015/12/04 rogid:CgjQBnnx1I8oVQ1gagep6qx5n4U6239 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 intact-crc:0C011C8104D843C8|rigid:1Ox3vg6JhgUDsDkB2s6IXmBa4Jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q18590 uniprotkb:G5EEG9 intact:EBI-2408618|ensemblmetazoa:C43H6.8.1 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 psi-mi:hlh15_caeel(display_long)|uniprotkb:hlh-15(gene name)|psi-mi:hlh-15(display_short)|uniprotkb:C43H6.8(orf name) psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2408631|imex:IM-12203-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040238|refseq:NP_508440.1|wormbase:C43H6.8|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:C43H6.8.1(transcript)|ensemblmetazoa:WBGene00001959(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:1/P826gEx2mRKLf+vK25uBBLtyA6239 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 intact-crc:B4567E4584BC6F2F|rigid:0mtNIlsQE8QoQsFEqOT17k+nHEs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q20941 uniprotkb:G5EEG9 intact:EBI-2408635|ensemblmetazoa:F57C12.3.1 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 psi-mi:q20941_caeel(display_long)|uniprotkb:hlh-19(gene name)|psi-mi:hlh-19(display_short)|uniprotkb:F57C12.3(orf name)|uniprotkb:CELE_F57C12.3(orf name) psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2408648|imex:IM-12203-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_508119.2|wormbase:F57C12.3|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:F57C12.3.1(transcript)|ensemblmetazoa:WBGene00001962(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032502"(developmental process)|go:"GO:0046983"(protein dimerization activity) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:R5SGwktd/j0OXptjZoJaeBXSk4M6239 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 intact-crc:079ECACB3BAF5571|rigid:plr9+qt3xgCBlsdZUljFX2w1bXI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EEG9 uniprotkb:Q10574 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 intact:EBI-2408652|ensemblmetazoa:T14F9.5.1 psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:lin32_caeel(display_long)|uniprotkb:lin-32(gene name)|psi-mi:lin-32(display_short)|uniprotkb:Abnormal cell lineage protein 32(gene name synonym)|uniprotkb:hlh-7(gene name synonym)|uniprotkb:T14F9.5(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2408669|imex:IM-12203-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) refseq:NP_508410.2|wormbase:T14F9.5|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:T14F9.5.1(transcript)|ensemblmetazoa:WBGene00003018(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0051179"(localization) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 rogid:whufEaX0EVo7vxwNu7YmkMnbgVw6239 intact-crc:BAC7E2F3CCCF4F26|rigid:FwrUfzfBye0Ua/H5ht9W96HvljE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EEG9 uniprotkb:P46581 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 intact:EBI-2408673|ensemblmetazoa:C34E10.7.1 psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:ndf1_caeel(display_long)|uniprotkb:cnd-1(gene name)|psi-mi:cnd-1(display_short)|uniprotkb:NeuroD(gene name synonym)|uniprotkb:C34E10.7(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2408689|imex:IM-12203-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) refseq:NP_498115.1|wormbase:C34E10.7|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR022575|interpro:IPR036638|ensemblmetazoa:C34E10.7.1(transcript)|ensemblmetazoa:WBGene00000561(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046983"(protein dimerization activity) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 rogid:r8UogfI+9unt1Heu/CMW+i4tB9U6239 intact-crc:904B126EA1C15DD3|rigid:aq8pvENCkluWSY0hv6N8FGi1jmk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EEG9 uniprotkb:Q18612 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 intact:EBI-2408693|ensemblmetazoa:C44C10.8.1 psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:hnd1_caeel(display_long)|uniprotkb:hnd-1(gene name)|psi-mi:hnd-1(display_short)|uniprotkb:C44C10.8(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2408710|imex:IM-12203-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) refseq:NP_509952.1|wormbase:C44C10.8|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:C44C10.8.1(transcript)|ensemblmetazoa:WBGene00001981(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008406"(gonad development)|go:"GO:0032502"(developmental process)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051149"(positive regulation of muscle cell differentiation) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 rogid:KyAt0x7XDHruyaEDnk7wAObGmdY6239 intact-crc:B43A61C73D35BC52|rigid:hHf7ObJhDVmWKDWqybPjksP1MF8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EEG9 uniprotkb:Q95XG7 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 intact:EBI-2408714|ensemblmetazoa:Y69A2AR.29.1 psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:ngn1_caeel(display_long)|uniprotkb:ngn-1(gene name)|psi-mi:ngn-1(display_short)|uniprotkb:Y69A2AR.29(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2408728|imex:IM-12203-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) refseq:NP_500236.1|wormbase:Y69A2AR.29|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR032666|ensemblmetazoa:WBGene00003595(gene)|ensemblmetazoa:Y69A2AR.29.1(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046983"(protein dimerization activity) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 rogid:JKgKvHPvhV+sMBVrpWMLzj94SE86239 intact-crc:0DEFF26F1C097249|rigid:RTpuk4KVhavLpI8Om5B8KnHsGLY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q22717 uniprotkb:G5EEG9 intact:EBI-2408732|intact:EBI-6743076|uniprotkb:P90977|ensemblmetazoa:T24B8.6.1 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 psi-mi:hlh3_caeel(display_long)|uniprotkb:hlh-3(gene name)|psi-mi:hlh-3(display_short)|uniprotkb:T24B8.6(orf name) psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2408743|imex:IM-12203-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495938.4|wormbase:T24B8.6|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:T24B8.6.1(transcript)|ensemblmetazoa:WBGene00001950(gene)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042427"(serotonin biosynthetic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046662"(regulation of oviposition)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2017/05/05 rogid:E1vkOZlB52YAs3CQ8N+LANoyTEY6239 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 intact-crc:8ECBA474BBC28533|rigid:afSHbv9Vo5AzhDbqM0uoEF0yxCM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EEG9 uniprotkb:P34555 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 intact:EBI-2408747|ensemblmetazoa:T05G5.2.1 psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:hlh4_caeel(display_long)|uniprotkb:hlh-4(gene name)|psi-mi:hlh-4(display_short)|uniprotkb:T05G5.2(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2408765|imex:IM-12203-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) refseq:NP_499150.1|wormbase:T05G5.2|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:T05G5.2.1(transcript)|ensemblmetazoa:WBGene00001951(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 rogid:kdeBAzawfYHXNDTuFuza1M8+PxI6239 intact-crc:2F402020CC0561CF|rigid:vH7YireiKTH1wtIu1T9x9yPbY34 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EEG9 uniprotkb:Q10007 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 intact:EBI-2408769|ensemblmetazoa:T15H9.3.1 psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:hlh6_caeel(display_long)|uniprotkb:hlh-6(gene name)|psi-mi:hlh-6(display_short)|uniprotkb:T15H9.3(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2408785|imex:IM-12203-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) refseq:NP_496070.1|wormbase:T15H9.3|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:T15H9.3.1(transcript)|ensemblmetazoa:WBGene00001952(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042995"(cell projection)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060465"(pharynx development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0110043"(positive regulation of pharynx morphogenesis)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:1905905"(pharyngeal gland morphogenesis) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 rogid:xm0zYJjkZQ9gmT39NNGxlVHgD5g6239 intact-crc:AE04F2D85D0D81AB|rigid:rkUdm4sx/2947um1V8VQdRsqbqU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22980 uniprotkb:P22980 intact:EBI-2408789|ensemblmetazoa:B0304.1b.1|ensemblmetazoa:B0304.1b.2 intact:EBI-2408789|ensemblmetazoa:B0304.1b.1|ensemblmetazoa:B0304.1b.2 psi-mi:myod1_caeel(display_long)|uniprotkb:hlh-1(gene name)|psi-mi:hlh-1(display_short)|uniprotkb:Helix-loop-helix protein 1(gene name synonym)|uniprotkb:B0304.1(orf name) psi-mi:myod1_caeel(display_long)|uniprotkb:hlh-1(gene name)|psi-mi:hlh-1(display_short)|uniprotkb:Helix-loop-helix protein 1(gene name synonym)|uniprotkb:B0304.1(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2408854|imex:IM-12203-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR039704|refseq:NP_001021892.1|refseq:NP_001021893.1|refseq:NP_494798.4|wormbase:B0304.1a|wormbase:B0304.1b|wormbase:B0304.1c|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:B0304.1b.1(transcript)|ensemblmetazoa:B0304.1b.2(transcript)|ensemblmetazoa:WBGene00001948(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051149"(positive regulation of muscle cell differentiation) interpro:IPR039704|refseq:NP_001021892.1|refseq:NP_001021893.1|refseq:NP_494798.4|wormbase:B0304.1a|wormbase:B0304.1b|wormbase:B0304.1c|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:B0304.1b.1(transcript)|ensemblmetazoa:B0304.1b.2(transcript)|ensemblmetazoa:WBGene00001948(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051149"(positive regulation of muscle cell differentiation) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:eywXRvNPsdS4BZHvdENEN20kEWg6239 rogid:eywXRvNPsdS4BZHvdENEN20kEWg6239 intact-crc:EBB09983E8D8033D|rigid:s0WTaT6C17jmm2gPWFYeV4H+z7s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EEH5 uniprotkb:G5EG44 intact:EBI-1182982|ensemblmetazoa:T19B10.11.1 intact:EBI-1182971|ensemblmetazoa:R03E9.1.1 psi-mi:mxl1_caeel(display_long)|uniprotkb:mxl-1(gene name)|psi-mi:mxl-1(display_short)|uniprotkb:T19B10.11(orf name) psi-mi:mdl1_caeel(display_long)|uniprotkb:mdl-1(gene name)|psi-mi:mdl-1(display_short)|uniprotkb:R03E9.1(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2408869|imex:IM-12203-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P90982(uniprot-removed-ac)|interpro:IPR036638|interpro:IPR037933|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_505856.1|ensemblmetazoa:T19B10.11.1(transcript)|ensemblmetazoa:WBGene00003509(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0071339"(MLL1 complex)|wormbase:T19B10.11 uniprotkb:Q21663(uniprot-removed-ac)|interpro:IPR036638|interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_509136.1|ensemblmetazoa:R03E9.1.1(transcript)|ensemblmetazoa:WBGene00003163(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|wormbase:R03E9.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:PbI7adE3kxBOJAPSolRoA5wI1yo6239 rogid:QFcUT/YNFv92SM6ifvWU+LRUe306239 intact-crc:06C99202671CD466|rigid:yN0HdlwIypSA/2A2xlAapg16CJc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9TZ70 uniprotkb:P41846 intact:EBI-2408874|ensemblmetazoa:F40G9.11.1 intact:EBI-2408887|uniprotkb:Q9BKE3|ensemblmetazoa:T20B12.6a.1 psi-mi:mxl2_caeel(display_long)|uniprotkb:mxl-2(gene name)|psi-mi:mxl-2(display_short)|uniprotkb:F40G9.11(orf name) psi-mi:wbs14_caeel(display_long)|uniprotkb:mml-1(gene name)|psi-mi:mml-1(display_short)|uniprotkb:mio(gene name synonym)|uniprotkb:MLX interactor(gene name synonym)|uniprotkb:T20B12.6(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2408909|imex:IM-12203-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497173.1|wormbase:F40G9.11|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-CEL-163765|ensemblmetazoa:F40G9.11.1(transcript)|ensemblmetazoa:WBGene00003510(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0046983"(protein dimerization activity) refseq:NP_498631.2|wormbase:T20B12.6a|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-CEL-163358|reactome:R-CEL-163765|ensemblmetazoa:T20B12.6a.1(transcript)|ensemblmetazoa:WBGene00003378(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0046983"(protein dimerization activity) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:C42XtC1fA2EN364oXqjXLK8HTz46239 rogid:zVVyJBUEqhBMBZiH5mK1/naL/uM6239 intact-crc:FB95A54EE4DE279B|rigid:+yzXI+JYUmsdv7DK4lCsb5lMONs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41846 uniprotkb:Q9TZ70 intact:EBI-2408887|uniprotkb:Q9BKE3|ensemblmetazoa:T20B12.6a.1 intact:EBI-2408874|ensemblmetazoa:F40G9.11.1 psi-mi:wbs14_caeel(display_long)|uniprotkb:mml-1(gene name)|psi-mi:mml-1(display_short)|uniprotkb:mio(gene name synonym)|uniprotkb:MLX interactor(gene name synonym)|uniprotkb:T20B12.6(orf name) psi-mi:mxl2_caeel(display_long)|uniprotkb:mxl-2(gene name)|psi-mi:mxl-2(display_short)|uniprotkb:F40G9.11(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2408917|imex:IM-12203-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498631.2|wormbase:T20B12.6a|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-CEL-163358|reactome:R-CEL-163765|ensemblmetazoa:T20B12.6a.1(transcript)|ensemblmetazoa:WBGene00003378(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0046983"(protein dimerization activity) refseq:NP_497173.1|wormbase:F40G9.11|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-CEL-163765|ensemblmetazoa:F40G9.11.1(transcript)|ensemblmetazoa:WBGene00003510(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0046983"(protein dimerization activity) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:zVVyJBUEqhBMBZiH5mK1/naL/uM6239 rogid:C42XtC1fA2EN364oXqjXLK8HTz46239 intact-crc:FB95A54EE4DE279B|rigid:+yzXI+JYUmsdv7DK4lCsb5lMONs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q18053 uniprotkb:Q18053 intact:EBI-2408925|ensemblmetazoa:C17C3.8.1 intact:EBI-2408925|ensemblmetazoa:C17C3.8.1 psi-mi:hlh26_caeel(display_long)|uniprotkb:hlh-26(gene name)|psi-mi:hlh-26(display_short)|uniprotkb:C17C3.8(orf name) psi-mi:hlh26_caeel(display_long)|uniprotkb:hlh-26(gene name)|psi-mi:hlh-26(display_short)|uniprotkb:C17C3.8(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2408951|imex:IM-12203-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495062.1|wormbase:C17C3.8|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:C17C3.8.1(transcript)|ensemblmetazoa:WBGene00001965(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis) refseq:NP_495062.1|wormbase:C17C3.8|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:C17C3.8.1(transcript)|ensemblmetazoa:WBGene00001965(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:IM9891wtWITBWOufIsO8e1JyVAA6239 rogid:IM9891wtWITBWOufIsO8e1JyVAA6239 intact-crc:7C35B902ED3712E6|rigid:ZAWpvbW4dDKGOiBHiaHSVkCba+Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P90953 uniprotkb:O02219 intact:EBI-2408965|uniprotkb:Q963J3|ensemblmetazoa:T01D3.2.1 intact:EBI-2408984|uniprotkb:G5EGG7|ensemblmetazoa:C25A1.11a.1 psi-mi:hlh34_caeel(display_long)|uniprotkb:T01D3.2(orf name)|uniprotkb:hlh-34(gene name)|psi-mi:hlh-34(display_short) psi-mi:aha1_caeel(display_long)|uniprotkb:aha-1(gene name)|psi-mi:aha-1(display_short)|uniprotkb:AHR-associated protein(gene name synonym)|uniprotkb:C25A1.11(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2409007|imex:IM-12203-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506391.2|wormbase:T01D3.2|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR035965|ensemblmetazoa:T01D3.2.1(transcript)|ensemblmetazoa:WBGene00011327(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0046983"(protein dimerization activity) wormbase:C25A1.11a|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR001067(Nuclear translocator)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|reactome:R-CEL-211945|reactome:R-CEL-8937144|wormbase:C25A1.11b|refseq:NP_001251326.1|refseq:NP_001251327.1|interpro:IPR035965|interpro:IPR036638|reactome:R-CEL-1234158|ensemblmetazoa:C25A1.11a.1(transcript)|ensemblmetazoa:WBGene00000095(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0022008"(neurogenesis)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0035176"(social behavior)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|caution:The reciprocal bait prey of this interaction may also have been demonstrated, but as the authors did not label the multiple prey spots, this could not be annotated.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:zC3yvnKIu6NUZ0apen/sdAOHaso6239 rogid:Lcv5zHJSFRPbzroqTtTH9i9Gs3M6239 intact-crc:1205F26C07DF5EB8|rigid:UCIV15IlqCFmIVQvZ+DaX6GX974 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9N410 uniprotkb:O02219 intact:EBI-2409166|ensemblmetazoa:Y39A3CR.6.1 intact:EBI-2408984|uniprotkb:G5EGG7|ensemblmetazoa:C25A1.11a.1 psi-mi:q9n410_caeel(display_long)|uniprotkb:hlh-33(gene name)|psi-mi:hlh-33(display_short)|uniprotkb:Y39A3CR.6(orf name)|uniprotkb:CELE_Y39A3CR.6(orf name) psi-mi:aha1_caeel(display_long)|uniprotkb:aha-1(gene name)|psi-mi:aha-1(display_short)|uniprotkb:AHR-associated protein(gene name synonym)|uniprotkb:C25A1.11(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2409178|imex:IM-12203-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011598(Helix-loop-helix DNA-binding)|wormbase:Y39A3CR.6|interpro:IPR036638|ensemblmetazoa:WBGene00021446(gene)|ensemblmetazoa:Y39A3CR.6.1(transcript)|go:"GO:0046983"(protein dimerization activity) wormbase:C25A1.11a|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR001067(Nuclear translocator)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|reactome:R-CEL-211945|reactome:R-CEL-8937144|wormbase:C25A1.11b|refseq:NP_001251326.1|refseq:NP_001251327.1|interpro:IPR035965|interpro:IPR036638|reactome:R-CEL-1234158|ensemblmetazoa:C25A1.11a.1(transcript)|ensemblmetazoa:WBGene00000095(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0022008"(neurogenesis)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0035176"(social behavior)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|caution:The reciprocal bait prey of this interaction may also have been demonstrated, but as the authors did not label the multiple prey spots, this could not be annotated.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2019/02/20 rogid:R1Pc/cjZ60aEb0V/bKgXfKXKsjA6239 rogid:Lcv5zHJSFRPbzroqTtTH9i9Gs3M6239 intact-crc:C400596F2055C61A|rigid:veC9NISGMPRPrGYiT88ZPjyTbvw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O02219 uniprotkb:O44712 intact:EBI-2408984|uniprotkb:G5EGG7|ensemblmetazoa:C25A1.11a.1 intact:EBI-2409183|intact:EBI-2923883|uniprotkb:Q93369|uniprotkb:Q564W4|ensemblmetazoa:C41G7.5a.1 psi-mi:aha1_caeel(display_long)|uniprotkb:aha-1(gene name)|psi-mi:aha-1(display_short)|uniprotkb:AHR-associated protein(gene name synonym)|uniprotkb:C25A1.11(orf name) psi-mi:ahr_caeel(display_long)|uniprotkb:ahr-1(gene name)|psi-mi:ahr-1(display_short)|uniprotkb:C41G7.5(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2409203|imex:IM-12203-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C25A1.11a|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR001067(Nuclear translocator)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|reactome:R-CEL-211945|reactome:R-CEL-8937144|wormbase:C25A1.11b|refseq:NP_001251326.1|refseq:NP_001251327.1|interpro:IPR035965|interpro:IPR036638|reactome:R-CEL-1234158|ensemblmetazoa:C25A1.11a.1(transcript)|ensemblmetazoa:WBGene00000095(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0022008"(neurogenesis)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0035176"(social behavior)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) interpro:IPR013655(PAS fold-3)|refseq:NP_001021036.1|refseq:NP_001021037.1|wormbase:C41G7.5a|wormbase:C41G7.5b|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|reactome:R-CEL-8937144|reactome:R-CEL-211945|interpro:IPR035965|interpro:IPR036638|interpro:IPR039091|ensemblmetazoa:C41G7.5a.1(transcript)|ensemblmetazoa:WBGene00000096(gene)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007610"(behavior)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0040013"(negative regulation of locomotion)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|caution:The reciprocal bait prey of this interaction may also have been demonstrated, but as the authors did not label the multiple prey spots, this could not be annotated.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:Lcv5zHJSFRPbzroqTtTH9i9Gs3M6239 rogid:YaPTok54iRAafHbyX73gpP76xsg6239 intact-crc:77A62096C96D95B2|rigid:bsCdYpKSxG9kCtzgq106I/RgHdw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O44712 uniprotkb:O02219 intact:EBI-2409183|intact:EBI-2923883|uniprotkb:Q93369|uniprotkb:Q564W4|ensemblmetazoa:C41G7.5a.1 intact:EBI-2408984|uniprotkb:G5EGG7|ensemblmetazoa:C25A1.11a.1 psi-mi:ahr_caeel(display_long)|uniprotkb:ahr-1(gene name)|psi-mi:ahr-1(display_short)|uniprotkb:C41G7.5(orf name) psi-mi:aha1_caeel(display_long)|uniprotkb:aha-1(gene name)|psi-mi:aha-1(display_short)|uniprotkb:AHR-associated protein(gene name synonym)|uniprotkb:C25A1.11(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2409208|imex:IM-12203-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013655(PAS fold-3)|refseq:NP_001021036.1|refseq:NP_001021037.1|wormbase:C41G7.5a|wormbase:C41G7.5b|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|reactome:R-CEL-8937144|reactome:R-CEL-211945|interpro:IPR035965|interpro:IPR036638|interpro:IPR039091|ensemblmetazoa:C41G7.5a.1(transcript)|ensemblmetazoa:WBGene00000096(gene)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007610"(behavior)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0040013"(negative regulation of locomotion)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding) wormbase:C25A1.11a|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR001067(Nuclear translocator)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|reactome:R-CEL-211945|reactome:R-CEL-8937144|wormbase:C25A1.11b|refseq:NP_001251326.1|refseq:NP_001251327.1|interpro:IPR035965|interpro:IPR036638|reactome:R-CEL-1234158|ensemblmetazoa:C25A1.11a.1(transcript)|ensemblmetazoa:WBGene00000095(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0022008"(neurogenesis)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0035176"(social behavior)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|caution:The reciprocal bait prey of this interaction may also have been demonstrated, but as the authors did not label the multiple prey spots, this could not be annotated.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:YaPTok54iRAafHbyX73gpP76xsg6239 rogid:Lcv5zHJSFRPbzroqTtTH9i9Gs3M6239 intact-crc:77A62096C96D95B2|rigid:bsCdYpKSxG9kCtzgq106I/RgHdw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O02219 uniprotkb:G5EFA5 intact:EBI-2408984|uniprotkb:G5EGG7|ensemblmetazoa:C25A1.11a.1 intact:EBI-313013 psi-mi:aha1_caeel(display_long)|uniprotkb:aha-1(gene name)|psi-mi:aha-1(display_short)|uniprotkb:AHR-associated protein(gene name synonym)|uniprotkb:C25A1.11(orf name) psi-mi:g5efa5_caeel(display_long) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2409213|imex:IM-12203-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C25A1.11a|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR001067(Nuclear translocator)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|reactome:R-CEL-211945|reactome:R-CEL-8937144|wormbase:C25A1.11b|refseq:NP_001251326.1|refseq:NP_001251327.1|interpro:IPR035965|interpro:IPR036638|reactome:R-CEL-1234158|ensemblmetazoa:C25A1.11a.1(transcript)|ensemblmetazoa:WBGene00000095(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0022008"(neurogenesis)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0035176"(social behavior)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) uniprotkb:Q18018(uniprot-removed-ac)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000014(PAS)|interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_506184.2|interpro:IPR035965|interpro:IPR036638 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|caution:The reciprocal bait prey of this interaction may also have been demonstrated, but as the authors did not label the multiple prey spots, this could not be annotated.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:Lcv5zHJSFRPbzroqTtTH9i9Gs3M6239 rogid:EEafPL6Ze3kxoYxzZofZMGWFFqg6239 intact-crc:6847917BCD041E52|rigid:dKBg4S+16MeI0gngulun4nrTVBQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O02219 uniprotkb:G5EGD2 intact:EBI-2408984|uniprotkb:G5EGG7|ensemblmetazoa:C25A1.11a.1 intact:EBI-319821|ensemblmetazoa:F38A6.3a.1|intact:EBI-2409218|uniprotkb:G5ECE6|uniprotkb:G5EDZ3|uniprotkb:G5EE28|uniprotkb:Q8I4D0 psi-mi:aha1_caeel(display_long)|uniprotkb:aha-1(gene name)|psi-mi:aha-1(display_short)|uniprotkb:AHR-associated protein(gene name synonym)|uniprotkb:C25A1.11(orf name) psi-mi:hif1_caeel(display_long)|uniprotkb:hif-1(gene name)|psi-mi:hif-1(display_short)|uniprotkb:Hypoxia-induced factor 1(gene name synonym)|uniprotkb:F38A6.3(orf name) psi-mi:"MI:0018"(two hybrid) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2409239|imex:IM-12203-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C25A1.11a|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR001067(Nuclear translocator)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|reactome:R-CEL-211945|reactome:R-CEL-8937144|wormbase:C25A1.11b|refseq:NP_001251326.1|refseq:NP_001251327.1|interpro:IPR035965|interpro:IPR036638|reactome:R-CEL-1234158|ensemblmetazoa:C25A1.11a.1(transcript)|ensemblmetazoa:WBGene00000095(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0022008"(neurogenesis)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0035176"(social behavior)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) uniprotkb:Q9TVM0(uniprot-removed-ac)|ensemblmetazoa:F38A6.3a.1(transcript)|ensemblmetazoa:WBGene00001851(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010286"(heat acclimation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071456"(cellular response to hypoxia)|wormbase:F38A6.3a|wormbase:F38A6.3b|wormbase:F38A6.3c|wormbase:F38A6.3d|wormbase:F38A6.3e|interpro:IPR000014(PAS)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|refseq:NP_001023891.2|refseq:NP_001023892.1|refseq:NP_001023893.1|refseq:NP_508008.4|refseq:NP_001023894.2|reactome:R-CEL-1234158|reactome:R-CEL-1234176|interpro:IPR035965|reactome:R-CEL-8951664|reactome:R-CEL-5689880 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/06 2014/10/16 rogid:Lcv5zHJSFRPbzroqTtTH9i9Gs3M6239 rogid:lxa2pZKZKX36zeQ2hCVZH0i5phk6239 intact-crc:ABC37060D9BAC14A|rigid:InbbU8AHX3l9W+uwZeddVfpuNHw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EEG9 uniprotkb:Q22717 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 intact:EBI-2408732|intact:EBI-6743076|uniprotkb:P90977|ensemblmetazoa:T24B8.6.1 psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:hlh3_caeel(display_long)|uniprotkb:hlh-3(gene name)|psi-mi:hlh-3(display_short)|uniprotkb:T24B8.6(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2409251|imex:IM-12203-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) refseq:NP_495938.4|wormbase:T24B8.6|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:T24B8.6.1(transcript)|ensemblmetazoa:WBGene00001950(gene)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042427"(serotonin biosynthetic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046662"(regulation of oviposition)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Figs. 3B and 3C, Supp. Fig. 4|comment:"Coexpressed in Late embryo (WBls:0000021), L1 larva (WBls:0000024), in the head neuron (WBbt:0006751), and P cell."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2009/08/06 2017/05/05 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 rogid:E1vkOZlB52YAs3CQ8N+LANoyTEY6239 intact-crc:F745385FB81EABBA|rigid:afSHbv9Vo5AzhDbqM0uoEF0yxCM false red fluorescent protein tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:G5EEG9 uniprotkb:P34555 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 intact:EBI-2408747|ensemblmetazoa:T05G5.2.1 psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:hlh4_caeel(display_long)|uniprotkb:hlh-4(gene name)|psi-mi:hlh-4(display_short)|uniprotkb:T05G5.2(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2409276|imex:IM-12203-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) refseq:NP_499150.1|wormbase:T05G5.2|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:T05G5.2.1(transcript)|ensemblmetazoa:WBGene00001951(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Figs. 3B and 3C, Supp. Fig. 4|comment:"Coexpressed in Mid embryo (WBls:0000015), Late embryo (WBls:0000021), L1 larva (WBls:0000024), L2 larva (WBls:0000027), L3 larva (WBls:0000035), L4 larva (WBls:0000038) and adults (WBls:0000041) in the head neuron (WBbt:0006751), body neuron (WBbt:0006752) and tail neuron (WBbt:0006759)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2009/08/06 2014/10/16 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 rogid:kdeBAzawfYHXNDTuFuza1M8+PxI6239 intact-crc:A187DA40CDA4EAE8|rigid:vH7YireiKTH1wtIu1T9x9yPbY34 false red fluorescent protein tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:G5EEG9 uniprotkb:Q23579 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 intact:EBI-2408537|ensemblmetazoa:ZK682.4.1 psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:hlh10_caeel(display_long)|uniprotkb:hlh-10(gene name)|psi-mi:hlh-10(display_short)|uniprotkb:CeABF-1(gene name synonym)|uniprotkb:ZK682.4(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2409296|imex:IM-12203-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) refseq:NP_505401.2|wormbase:ZK682.4|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:WBGene00001954(gene)|ensemblmetazoa:ZK682.4.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032502"(developmental process)|go:"GO:0046982"(protein heterodimerization activity) psi-mi:"MI:0469"(intact) - - figure legend:Figs. 3B and 3C, Supp. Fig. 4|comment:"Coexpressed in Late embryo (WBls:0000021), L1 larva (WBls:0000024), L2 larva (WBls:0000027), L3 larva (WBls:0000035) and L4 larva (WBls:0000038) in the head neuron (WBbt:0006751), body neuron (WBbt:0006752), tail neuron (WBbt:0006759) and vulva (WBbt:0006748)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2009/08/06 2014/10/16 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 rogid:O+GVIebahoAQhMXajlJky1OvjMg6239 intact-crc:08080BAFB2064954|rigid:iXCfXFg6RdXQQtKKAZ/DsZ35m4o false red fluorescent protein tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q18590 uniprotkb:G5EEG9 intact:EBI-2408618|ensemblmetazoa:C43H6.8.1 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 psi-mi:hlh15_caeel(display_long)|uniprotkb:hlh-15(gene name)|psi-mi:hlh-15(display_short)|uniprotkb:C43H6.8(orf name) psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2409316|imex:IM-12203-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040238|refseq:NP_508440.1|wormbase:C43H6.8|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:C43H6.8.1(transcript)|ensemblmetazoa:WBGene00001959(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Figs. 3B and 3C, Supp. Fig. 4|comment:"Coexpressed in Mid embryo (WBls:0000015), Late embryo (WBls:0000021) and L1 larva (WBls:0000024) in the head neuron (WBbt:0006751), and tail neuron (WBbt:0006759)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2009/08/06 2014/10/16 rogid:1/P826gEx2mRKLf+vK25uBBLtyA6239 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 intact-crc:01972A242D203B6A|rigid:0mtNIlsQE8QoQsFEqOT17k+nHEs false green fluorescent protein tag:?-? red fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q20941 uniprotkb:G5EEG9 intact:EBI-2408635|ensemblmetazoa:F57C12.3.1 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 psi-mi:q20941_caeel(display_long)|uniprotkb:hlh-19(gene name)|psi-mi:hlh-19(display_short)|uniprotkb:F57C12.3(orf name)|uniprotkb:CELE_F57C12.3(orf name) psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2409342|imex:IM-12203-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_508119.2|wormbase:F57C12.3|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:F57C12.3.1(transcript)|ensemblmetazoa:WBGene00001962(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032502"(developmental process)|go:"GO:0046983"(protein dimerization activity) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Figs. 3B and 3C, Supp. Fig. 4|comment:"Coexpressed in Mid embryo (WBls:0000015), Late embryo (WBls:0000021) and L1 larva (WBls:0000024)in the head neuron (WBbt:0006751) and tail neuron (WBbt:0006759)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2009/08/06 2014/10/16 rogid:R5SGwktd/j0OXptjZoJaeBXSk4M6239 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 intact-crc:61E006E0CB70C3DB|rigid:plr9+qt3xgCBlsdZUljFX2w1bXI false green fluorescent protein tag:?-? red fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q10574 uniprotkb:G5EEG9 intact:EBI-2408652|ensemblmetazoa:T14F9.5.1 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 psi-mi:lin32_caeel(display_long)|uniprotkb:lin-32(gene name)|psi-mi:lin-32(display_short)|uniprotkb:Abnormal cell lineage protein 32(gene name synonym)|uniprotkb:hlh-7(gene name synonym)|uniprotkb:T14F9.5(orf name) psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2409390|imex:IM-12203-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_508410.2|wormbase:T14F9.5|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:T14F9.5.1(transcript)|ensemblmetazoa:WBGene00003018(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0051179"(localization) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Figs. 3B and 3C, Supp. Fig. 4|comment:"Coexpressed in Mid embryo (WBls:0000015), Late embryo (WBls:0000021), L1 larva (WBls:0000024), L2 larva (WBls:0000027), L3 larva (WBls:0000035), L4 larva (WBls:0000038) and adults (WBls:0000041) in the distal tip cells (WBbt:0006865), head neuron (WBbt:0006751), body neuron (WBbt:0006752), head hypodermis (WBbt:0005373) and tail hypodermis (WBbt:0006978)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2009/08/06 2014/10/16 rogid:whufEaX0EVo7vxwNu7YmkMnbgVw6239 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 intact-crc:10D2A954BC8023F8|rigid:FwrUfzfBye0Ua/H5ht9W96HvljE false green fluorescent protein tag:?-? red fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P46581 uniprotkb:G5EEG9 intact:EBI-2408673|ensemblmetazoa:C34E10.7.1 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 psi-mi:ndf1_caeel(display_long)|uniprotkb:cnd-1(gene name)|psi-mi:cnd-1(display_short)|uniprotkb:NeuroD(gene name synonym)|uniprotkb:C34E10.7(orf name) psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2409417|imex:IM-12203-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498115.1|wormbase:C34E10.7|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR022575|interpro:IPR036638|ensemblmetazoa:C34E10.7.1(transcript)|ensemblmetazoa:WBGene00000561(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046983"(protein dimerization activity) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Figs. 3B and 3C, Supp. Fig. 4|comment:"Coexpressed in Mid embryo (WBls:0000015), Late embryo (WBls:0000021), L1 larva (WBls:0000024) and L2 larva (WBls:0000027) in the head neuron (WBbt:0006751), body neuron (WBbt:0006752), head hypodermis (WBbt:0005373) tail neuron (WBbt:0006759) and head hypodermis (WBbt:0005373)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2009/08/06 2014/10/16 rogid:r8UogfI+9unt1Heu/CMW+i4tB9U6239 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 intact-crc:96DB648D05696768|rigid:aq8pvENCkluWSY0hv6N8FGi1jmk false green fluorescent protein tag:?-? red fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:G5EEG9 uniprotkb:Q11094 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 intact:EBI-2408513|uniprotkb:O76255|ensemblmetazoa:C02B8.4.1 psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:twist_caeel(display_long)|uniprotkb:hlh-8(gene name)|psi-mi:hlh-8(display_short)|uniprotkb:CeTwist(gene name synonym)|uniprotkb:Helix-loop-helix protein 8(gene name synonym)|uniprotkb:C02B8.4(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2409454|imex:IM-12203-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) refseq:NP_509367.1|wormbase:C02B8.4|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015789(Twist)|interpro:IPR036638|ensemblmetazoa:C02B8.4.1(transcript)|ensemblmetazoa:WBGene00001953(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0032502"(developmental process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0072327"(vulval cell fate specification) psi-mi:"MI:0469"(intact) - - figure legend:Figs. 3B and 3C, Supp. Fig. 4|comment:"Coexpressed in Mid embryo (WBls:0000015), Late embryo (WBls:0000021), L1 larva (WBls:0000024), L2 larva (WBls:0000027), L3 larva (WBls:0000035), L4 larva (WBls:0000038) and adults (WBls:0000041) in the head neuron (WBbt:0006751) and vulva (WBbt:0006748)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2009/08/06 2014/10/16 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 rogid:SmDeYwVWHbIAP3B+lBN1AKZ6Xlg6239 intact-crc:636D72F9E84A0367|rigid:Sx6A+uWiBmzwZrCupeni7lueC2M false red fluorescent protein tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q10007 uniprotkb:G5EEG9 intact:EBI-2408769|ensemblmetazoa:T15H9.3.1 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 psi-mi:hlh6_caeel(display_long)|uniprotkb:hlh-6(gene name)|psi-mi:hlh-6(display_short)|uniprotkb:T15H9.3(orf name) psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2409490|imex:IM-12203-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496070.1|wormbase:T15H9.3|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:T15H9.3.1(transcript)|ensemblmetazoa:WBGene00001952(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042995"(cell projection)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060465"(pharynx development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0110043"(positive regulation of pharynx morphogenesis)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:1905905"(pharyngeal gland morphogenesis) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Figs. 3B and 3C, Supp. Fig. 4|comment:"Coexpressed in Mid embryo (WBls:0000015), Late embryo (WBls:0000021) and L1 larva (WBls:0000024), in the Pharyngeal gland (WBbt:0005788)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2009/08/06 2014/10/16 rogid:xm0zYJjkZQ9gmT39NNGxlVHgD5g6239 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 intact-crc:EC2857460B5DCEF0|rigid:rkUdm4sx/2947um1V8VQdRsqbqU false green fluorescent protein tag:?-? red fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q20561 uniprotkb:G5EEG9 intact:EBI-2408554|ensemblmetazoa:F48D6.3.1 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 psi-mi:hlh13_caeel(display_long)|uniprotkb:hlh-13(gene name)|psi-mi:hlh-13(display_short)|uniprotkb:cnato3(gene name synonym)|uniprotkb:ferd-3l(gene name synonym)|uniprotkb:Nephew of atonal 3(gene name synonym)|uniprotkb:Fer3-like protein(gene name synonym)|uniprotkb:F48D6.3(orf name) psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2409528|imex:IM-12203-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_508725.1|wormbase:F48D6.3|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:F48D6.3.1(transcript)|ensemblmetazoa:WBGene00001957(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032502"(developmental process)|go:"GO:0043054"(dauer exit)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0140297"(DNA-binding transcription factor binding) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Figs. 3B and 3C, Supp. Fig. 4|comment:"Coexpressed in Late embryo (WBls:0000021), L1 larva (WBls:0000024), L2 larva (WBls:0000027), L3 larva (WBls:0000035) and L4 larva (WBls:0000038), in the head neuron (WBbt:0006751) and tail neuron (WBbt:0006759)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2009/08/06 2014/10/16 rogid:I9gZm44FWbjyw7sWcnKAeydPguA6239 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 intact-crc:E53DBBA7FDCF6DFB|rigid:aVIRmELyDAGWa2HtIG2mYA5WthE false green fluorescent protein tag:?-? red fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:G5EEG9 uniprotkb:Q18612 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 intact:EBI-2408693|ensemblmetazoa:C44C10.8.1 psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:hnd1_caeel(display_long)|uniprotkb:hnd-1(gene name)|psi-mi:hnd-1(display_short)|uniprotkb:C44C10.8(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2409590|imex:IM-12203-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) refseq:NP_509952.1|wormbase:C44C10.8|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:C44C10.8.1(transcript)|ensemblmetazoa:WBGene00001981(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008406"(gonad development)|go:"GO:0032502"(developmental process)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051149"(positive regulation of muscle cell differentiation) psi-mi:"MI:0469"(intact) - - figure legend:Figs. 3B and 3C, Supp. Fig. 4|comment:"Coexpressed in Mid embryo (WBls:0000015), Late embryo (WBls:0000021), L1 larva (WBls:0000024), L2 larva (WBls:0000027), L3 larva (WBls:0000035), L4 larva (WBls:0000038) and adults (WBls:0000041) in the distal tip cells (WBbt:0006865), head neuron (WBbt:0006751), body neuron (WBbt:0006752) and tail neuron (WBbt:0006759)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2009/08/06 2014/10/16 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 rogid:KyAt0x7XDHruyaEDnk7wAObGmdY6239 intact-crc:C8455BB814872AEA|rigid:hHf7ObJhDVmWKDWqybPjksP1MF8 false red fluorescent protein tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q95XG7 uniprotkb:G5EEG9 intact:EBI-2408714|ensemblmetazoa:Y69A2AR.29.1 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 psi-mi:ngn1_caeel(display_long)|uniprotkb:ngn-1(gene name)|psi-mi:ngn-1(display_short)|uniprotkb:Y69A2AR.29(orf name) psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2409647|imex:IM-12203-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500236.1|wormbase:Y69A2AR.29|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR032666|ensemblmetazoa:WBGene00003595(gene)|ensemblmetazoa:Y69A2AR.29.1(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046983"(protein dimerization activity) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Figs. 3B and 3C, Supp. Fig. 4|comment:"Coexpressed in Mid embryo (WBls:0000015), Late embryo (WBls:0000021), L1 larva (WBls:0000024), L2 larva (WBls:0000027), L3 larva (WBls:0000035) and L4 larva (WBls:0000038) in the distal tip cells (WBbt:0006865), head neuron (WBbt:0006751) and tail neuron (WBbt:0006759)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2009/08/06 2014/10/16 rogid:JKgKvHPvhV+sMBVrpWMLzj94SE86239 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 intact-crc:0A7CAC02BF7DE82C|rigid:RTpuk4KVhavLpI8Om5B8KnHsGLY false green fluorescent protein tag:?-? red fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q18277 uniprotkb:G5EEG9 intact:EBI-2408599|ensemblmetazoa:C28C12.8.1 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 psi-mi:hlh12_caeel(display_long)|uniprotkb:mig-24(gene name synonym)|uniprotkb:C28C12.8(orf name)|uniprotkb:hlh-12(gene name)|psi-mi:hlh-12(display_short) psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Grove et al. (2009) imex:IM-12203|pubmed:19632181 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2409679|imex:IM-12203-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501445.1|wormbase:C28C12.8|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:C28C12.8.1(transcript)|ensemblmetazoa:WBGene00001956(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032502"(developmental process)|go:"GO:0046983"(protein dimerization activity) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Figs. 3B and 3C, Supp. Fig. 4|comment:"Coexpressed in L3 larva (WBls:0000035), L4 larva (WBls:0000038) and adults (WBls:0000041) in the distal tip cells (WBbt:0006865), head neuron (WBbt:0006751), body neuron (WBbt:0006752) and tail neuron (WBbt:0006759)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2009/08/06 2014/10/16 rogid:z9yjzE0A72GCsEEIrPa7j3OynM86239 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 intact-crc:D46370FFFE0722FC|rigid:rpedziggAhR09R2CDAI7B7Biwyk false green fluorescent protein tag:?-? red fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)