#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q99933 uniprotkb:Q9Y618 intact:EBI-1030678|uniprotkb:O75315|uniprotkb:Q14414|uniprotkb:Q96TG2|uniprotkb:Q9Y2V4|uniprotkb:Q53H32|uniprotkb:Q5VZE8|uniprotkb:Q5VZE9|uniprotkb:Q5VZF0|ensembl:ENSP00000489189 intact:EBI-80830|uniprotkb:Q9Y5U0|uniprotkb:O00613|uniprotkb:O15416|uniprotkb:Q13354|uniprotkb:O15421|intact:EBI-28976851|uniprotkb:Q56D06|uniprotkb:Q59GM0|ensembl:ENSP00000384018 psi-mi:bag1_human(display_long)|uniprotkb:BAG1(gene name)|psi-mi:BAG1(display_short)|uniprotkb:Bcl-2-associated athanogene 1(gene name synonym)|uniprotkb:HAP(gene name synonym) psi-mi:ncor2_human(display_long)|uniprotkb:NCOR2(gene name)|psi-mi:NCOR2(display_short)|uniprotkb:CTG26(gene name synonym)|uniprotkb:Silencing mediator of retinoic acid and thyroid hormone receptor(gene name synonym)|uniprotkb:Thyroid-, retinoic-acid-receptor-associated corepressor(gene name synonym)|uniprotkb:T3 receptor-associating factor(gene name synonym)|uniprotkb:CTG repeat protein 26(gene name synonym)|uniprotkb:SMAP270(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hong et al. (2009) pubmed:19595997|mint:MINT-7216159|mint:d-09-00825 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7098501|mint:MINT-7216175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001165886.1|refseq:NP_004314.5|ensembl:ENSG00000107262(gene)|ensembl:ENST00000634734(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050821"(protein stabilization)|interpro:IPR017093(Molecular chaperone regulator BAG-1)|interpro:IPR029071|interpro:IPR036533|interpro:IPR039773|mint:Q99933|rcsb pdb:1HX1|rcsb pdb:1WXV|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|reactome:R-HSA-3371453|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|dip:DIP-3341N|mint:MINT-7216179(identity) ensembl:ENSP00000384018|refseq:NP_001070729.2|refseq:NP_001193583.1|refseq:NP_006303.4|dip:DIP-951N|ensembl:ENSG00000196498(gene)|ensembl:ENST00000405201(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007595"(lactation)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010565"(regulation of cellular ketone metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|mint:Q9Y618|rcsb pdb:1KKQ|rcsb pdb:1R2B|rcsb pdb:1XC5|rcsb pdb:2GPV|rcsb pdb:2L5G|rcsb pdb:2LTP|rcsb pdb:2ODD|rcsb pdb:2RT5|rcsb pdb:3R29|rcsb pdb:3R2A|rcsb pdb:4A69|rcsb pdb:4OAR|rcsb pdb:5X8Q|rcsb pdb:5X8X|rcsb pdb:5ZOO|rcsb pdb:5ZOP|rcsb pdb:6A22|rcsb pdb:6IVX|rcsb pdb:6PDZ|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9623433|reactome:R-HSA-9707564|mint:MINT-7216177(identity) - - - figure legend:F1|comment:homomint|comment:mint|comment:We used human identifiers for COS7 proteins taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/07/07 2018/09/18 rogid:wDyAGECTy45td5tL4mnwa1txPO49606 rogid:58SZfHIXN3dZN93fsiVHbbEwD0g9606 intact-crc:FE230FA8C65F7304|rigid:ElojuwO9VRTUJYNmoQqdJpoqilA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O15379 uniprotkb:Q99933 intact:EBI-607682|uniprotkb:O43268|uniprotkb:Q9UEI5|uniprotkb:Q9UEV0|uniprotkb:D3DQE1|ensembl:ENSP00000302967 intact:EBI-1030678|uniprotkb:O75315|uniprotkb:Q14414|uniprotkb:Q96TG2|uniprotkb:Q9Y2V4|uniprotkb:Q53H32|uniprotkb:Q5VZE8|uniprotkb:Q5VZE9|uniprotkb:Q5VZF0|ensembl:ENSP00000489189 psi-mi:hdac3_human(display_long)|uniprotkb:HDAC3(gene name)|psi-mi:HDAC3(display_short)|uniprotkb:RPD3-2(gene name synonym)|uniprotkb:SMAP45(gene name synonym) psi-mi:bag1_human(display_long)|uniprotkb:BAG1(gene name)|psi-mi:BAG1(display_short)|uniprotkb:Bcl-2-associated athanogene 1(gene name synonym)|uniprotkb:HAP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hong et al. (2009) pubmed:19595997|mint:MINT-7216159|mint:d-09-00825 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7098489|mint:MINT-7216164 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003874.2|dip:DIP-24253N|ensembl:ENSG00000171720(gene)|ensembl:ENST00000305264(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:O15379|rcsb pdb:4A69|reactome:R-HSA-1368071|reactome:R-HSA-193670|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-390471|reactome:R-HSA-400206|reactome:R-HSA-5617472|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-400253|mint:MINT-7216167(identity) refseq:NP_001165886.1|refseq:NP_004314.5|ensembl:ENSG00000107262(gene)|ensembl:ENST00000634734(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050821"(protein stabilization)|interpro:IPR017093(Molecular chaperone regulator BAG-1)|interpro:IPR029071|interpro:IPR036533|interpro:IPR039773|mint:Q99933|rcsb pdb:1HX1|rcsb pdb:1WXV|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|reactome:R-HSA-3371453|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|dip:DIP-3341N|mint:MINT-7216166(identity) - - - figure legend:F1|comment:homomint|comment:mint|comment:We used human identifiers for COS7 proteins taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/07/07 2014/10/16 rogid:X5pnE98s15eXKev3nauN7ri5kqg9606 rogid:wDyAGECTy45td5tL4mnwa1txPO49606 intact-crc:12BEE3F686F6B6AE|rigid:XrQjAarimgVCuG1it7iI+EialkQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O75376 uniprotkb:Q99933 intact:EBI-347233|uniprotkb:E9PGV6|uniprotkb:Q86YY0|uniprotkb:Q9UPV5|uniprotkb:Q9UQ18|intact:EBI-28976482|ensembl:ENSP00000268712|uniprotkb:B3DLF8 intact:EBI-1030678|uniprotkb:O75315|uniprotkb:Q14414|uniprotkb:Q96TG2|uniprotkb:Q9Y2V4|uniprotkb:Q53H32|uniprotkb:Q5VZE8|uniprotkb:Q5VZE9|uniprotkb:Q5VZF0|ensembl:ENSP00000489189 psi-mi:ncor1_human(display_long)|uniprotkb:NCOR1(gene name)|psi-mi:NCOR1(display_short)|uniprotkb:KIAA1047(gene name synonym) psi-mi:bag1_human(display_long)|uniprotkb:BAG1(gene name)|psi-mi:BAG1(display_short)|uniprotkb:Bcl-2-associated athanogene 1(gene name synonym)|uniprotkb:HAP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hong et al. (2009) pubmed:19595997|mint:MINT-7216159|mint:d-09-00825 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7098527|mint:MINT-7216183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-29402N|ensembl:ENSP00000268712|ensembl:ENST00000395848|ensembl:ENSP00000379189|ensembl:ENST00000395851|ensembl:ENSP00000379192|ensembl:ENSG00000141027(gene)|ensembl:ENST00000268712(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016020"(membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|mint:O75376|rcsb pdb:2EQR|rcsb pdb:3KMZ|rcsb pdb:3N00|rcsb pdb:4MDD|rcsb pdb:4WVD|rcsb pdb:6ONI|rcsb pdb:6WMQ|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-1251985|reactome:R-HSA-1368071|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2173795|reactome:R-HSA-2644606|rcsb pdb:3H52|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|refseq:XP_011522388.1|refseq:NP_001177369.1|refseq:NP_006302.2|refseq:NP_001177367.1|mint:MINT-7216185(identity) refseq:NP_001165886.1|refseq:NP_004314.5|ensembl:ENSG00000107262(gene)|ensembl:ENST00000634734(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050821"(protein stabilization)|interpro:IPR017093(Molecular chaperone regulator BAG-1)|interpro:IPR029071|interpro:IPR036533|interpro:IPR039773|mint:Q99933|rcsb pdb:1HX1|rcsb pdb:1WXV|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|reactome:R-HSA-3371453|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|dip:DIP-3341N|mint:MINT-7216187(identity) - - - figure legend:F1|comment:homomint|comment:mint|comment:We used human identifiers for COS7 proteins taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/07/07 2014/10/16 rogid:8W82xLRBbuJwVpXSvxoGQBu0v7Y9606 rogid:wDyAGECTy45td5tL4mnwa1txPO49606 intact-crc:0A3B63137AEFCED7|rigid:XZxWRxo5ejGXvfGo61iQm66V4Ms false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)