#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q13601 uniprotkb:Q9H171 intact:EBI-744525|intact:EBI-28971604|ensembl:ENSP00000229214|uniprotkb:Q8NEA8|uniprotkb:Q8TC37|uniprotkb:Q96AT5|uniprotkb:A0FIK6|uniprotkb:A0JLP0|uniprotkb:B2R989|uniprotkb:E7EUQ0 intact:EBI-6264672|ensembl:ENSP00000360215|uniprotkb:A2A2F7|uniprotkb:B3KVA1|uniprotkb:Q5JY39|uniprotkb:Q9BYW4|uniprotkb:F5GYT1 psi-mi:krr1_human(display_long)|uniprotkb:HIV-1 Rev-binding protein 2(gene name synonym)|uniprotkb:Rev-interacting protein 1(gene name synonym)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:HRB2(gene name synonym)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym) psi-mi:zbp1_human(display_long)|uniprotkb:ZBP1(gene name)|psi-mi:ZBP1(display_short)|uniprotkb:C20orf183(gene name synonym)|uniprotkb:DLM1(gene name synonym)|uniprotkb:Tumor stroma and activated macrophage protein DLM-1(gene name synonym)|uniprotkb:DNA-dependent activator of IFN-regulatory factors(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Rebsamen et al. (2009) pubmed:19590578|imex:IM-13920|mint:MINT-7255923|doi:10.1038/embor.2009.109 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7092210|mint:MINT-7255929|imex:IM-13920-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000229214|ensembl:ENST00000438169|ensembl:ENSP00000411740|ensembl:ENSG00000111615(gene)|ensembl:ENST00000229214(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045171"(intercellular bridge)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|mint:Q13601|refseq:NP_008974.5|reactome:R-HSA-6790901|reactome:R-HSA-6791226|mint:MINT-7255931(identity) ensembl:ENSG00000124256(gene)|ensembl:ENST00000371173(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003692"(left-handed Z-DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070269"(pyroptosis)|go:"GO:2000659"(regulation of interleukin-1-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042361|interpro:IPR042371|mint:Q9H171|rcsb pdb:2L4M|rcsb pdb:2LNB|rcsb pdb:3EYI|rcsb pdb:4KA4|reactome:R-HSA-1606322|reactome:R-HSA-1606341|reactome:R-HSA-1810476|reactome:R-HSA-3134975|reactome:R-HSA-9679191|go:"GO:0050727"(regulation of inflammatory response)|refseq:NP_001310895.1|refseq:NP_001153889.1|refseq:NP_001153890.1|refseq:NP_110403.2|refseq:NP_001153891.1|dip:DIP-44121N|mint:MINT-7255932(identity) - - - figure legend:F1B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/08/08 2014/10/16 rogid:uBKNL/aw4wEssKJulbqQVWcH7ZI9606 rogid:Tu0wt0TeuDYF8q++Zl97sy6weZQ9606 intact-crc:EEE774F2630B8C5E|rigid:pZBEf8nGi2WtEyiqgCr2X5MbbDE false flag tag:?-?(MINT-7255934) tag:?-?(MINT-7255938) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9H171 uniprotkb:Q13601 intact:EBI-6264672|ensembl:ENSP00000360215|uniprotkb:A2A2F7|uniprotkb:B3KVA1|uniprotkb:Q5JY39|uniprotkb:Q9BYW4|uniprotkb:F5GYT1 intact:EBI-744525|intact:EBI-28971604|ensembl:ENSP00000229214|uniprotkb:Q8NEA8|uniprotkb:Q8TC37|uniprotkb:Q96AT5|uniprotkb:A0FIK6|uniprotkb:A0JLP0|uniprotkb:B2R989|uniprotkb:E7EUQ0 psi-mi:zbp1_human(display_long)|uniprotkb:ZBP1(gene name)|psi-mi:ZBP1(display_short)|uniprotkb:C20orf183(gene name synonym)|uniprotkb:DLM1(gene name synonym)|uniprotkb:Tumor stroma and activated macrophage protein DLM-1(gene name synonym)|uniprotkb:DNA-dependent activator of IFN-regulatory factors(gene name synonym) psi-mi:krr1_human(display_long)|uniprotkb:HIV-1 Rev-binding protein 2(gene name synonym)|uniprotkb:Rev-interacting protein 1(gene name synonym)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:HRB2(gene name synonym)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Rebsamen et al. (2009) pubmed:19590578|imex:IM-13920|mint:MINT-7255923|doi:10.1038/embor.2009.109 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7092228|mint:MINT-7255942|imex:IM-13920-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000124256(gene)|ensembl:ENST00000371173(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003692"(left-handed Z-DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070269"(pyroptosis)|go:"GO:2000659"(regulation of interleukin-1-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042361|interpro:IPR042371|mint:Q9H171|rcsb pdb:2L4M|rcsb pdb:2LNB|rcsb pdb:3EYI|rcsb pdb:4KA4|reactome:R-HSA-1606322|reactome:R-HSA-1606341|reactome:R-HSA-1810476|reactome:R-HSA-3134975|reactome:R-HSA-9679191|go:"GO:0050727"(regulation of inflammatory response)|refseq:NP_001310895.1|refseq:NP_001153889.1|refseq:NP_001153890.1|refseq:NP_110403.2|refseq:NP_001153891.1|dip:DIP-44121N|mint:MINT-7255944(identity) ensembl:ENSP00000229214|ensembl:ENST00000438169|ensembl:ENSP00000411740|ensembl:ENSG00000111615(gene)|ensembl:ENST00000229214(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045171"(intercellular bridge)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|mint:Q13601|refseq:NP_008974.5|reactome:R-HSA-6790901|reactome:R-HSA-6791226|mint:MINT-7255948(identity) - - - figure legend:F1C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/08/08 2014/10/16 rogid:Tu0wt0TeuDYF8q++Zl97sy6weZQ9606 rogid:uBKNL/aw4wEssKJulbqQVWcH7ZI9606 intact-crc:C3106AE35BA2E3C7|rigid:pZBEf8nGi2WtEyiqgCr2X5MbbDE false flag tag:?-?(MINT-7255945) tag:?-?(MINT-7255949)|binding-associated region:?-?(MINT-7255954) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9H171 uniprotkb:Q9Y572 intact:EBI-6264672|ensembl:ENSP00000360215|uniprotkb:A2A2F7|uniprotkb:B3KVA1|uniprotkb:Q5JY39|uniprotkb:Q9BYW4|uniprotkb:F5GYT1 intact:EBI-298250|intact:EBI-358587|uniprotkb:C4AM87|uniprotkb:Q5J795|uniprotkb:Q5J796|uniprotkb:Q6P5Y1|uniprotkb:B4DJL9|ensembl:ENSP00000216274|ensembl:ENSP00000495490 psi-mi:zbp1_human(display_long)|uniprotkb:ZBP1(gene name)|psi-mi:ZBP1(display_short)|uniprotkb:C20orf183(gene name synonym)|uniprotkb:DLM1(gene name synonym)|uniprotkb:Tumor stroma and activated macrophage protein DLM-1(gene name synonym)|uniprotkb:DNA-dependent activator of IFN-regulatory factors(gene name synonym) psi-mi:ripk3_human(display_long)|uniprotkb:RIPK3(gene name)|psi-mi:RIPK3(display_short)|uniprotkb:RIP3(gene name synonym)|uniprotkb:RIP-like protein kinase 3(gene name synonym)|uniprotkb:Receptor-interacting protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Rebsamen et al. (2009) pubmed:19590578|imex:IM-13920|mint:MINT-7255923|doi:10.1038/embor.2009.109 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7092290|mint:MINT-7255987|imex:IM-13920-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000124256(gene)|ensembl:ENST00000371173(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003692"(left-handed Z-DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070269"(pyroptosis)|go:"GO:2000659"(regulation of interleukin-1-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042361|interpro:IPR042371|mint:Q9H171|rcsb pdb:2L4M|rcsb pdb:2LNB|rcsb pdb:3EYI|rcsb pdb:4KA4|reactome:R-HSA-1606322|reactome:R-HSA-1606341|reactome:R-HSA-1810476|reactome:R-HSA-3134975|reactome:R-HSA-9679191|go:"GO:0050727"(regulation of inflammatory response)|refseq:NP_001310895.1|refseq:NP_001153889.1|refseq:NP_001153890.1|refseq:NP_110403.2|refseq:NP_001153891.1|dip:DIP-44121N|mint:MINT-7255993(identity) refseq:NP_006862.2|dip:DIP-27519N|ensembl:ENSG00000129465(gene)|ensembl:ENSG00000285379(gene)|ensembl:ENST00000216274(transcript)|ensembl:ENST00000646516(transcript)|go:"GO:0001914"(regulation of T cell mediated cytotoxicity)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007165"(signal transduction)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046006"(regulation of activated T cell proliferation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070235"(regulation of activation-induced cell death of T cells)|go:"GO:0070266"(necroptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:0097528"(execution phase of necroptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000452"(regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR025735|mint:Q9Y572|rcsb pdb:5V7Z|rcsb pdb:5ZCK|rcsb pdb:7DAC|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-2562578|reactome:R-HSA-3295583|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-9013957|reactome:R-HSA-937041|reactome:R-HSA-9686347|rcsb pdb:7DA4|mint:MINT-7255989(identity) - - - figure legend:F1E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/08/08 2014/10/16 rogid:Tu0wt0TeuDYF8q++Zl97sy6weZQ9606 rogid:UgojU4aAUAG5RCZ55KR39AelO249606 intact-crc:8912605DB922DD95|rigid:7sZIR8pj/sPVyAj4Dp2CVJJaLvY false flag tag:?-?(MINT-7255994) binding-associated region:194-518(MINT-7255999)|tag:?-?(MINT-7255990) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q13601 uniprotkb:Q9H171 intact:EBI-744525|intact:EBI-28971604|ensembl:ENSP00000229214|uniprotkb:Q8NEA8|uniprotkb:Q8TC37|uniprotkb:Q96AT5|uniprotkb:A0FIK6|uniprotkb:A0JLP0|uniprotkb:B2R989|uniprotkb:E7EUQ0 intact:EBI-6264672|ensembl:ENSP00000360215|uniprotkb:A2A2F7|uniprotkb:B3KVA1|uniprotkb:Q5JY39|uniprotkb:Q9BYW4|uniprotkb:F5GYT1 psi-mi:krr1_human(display_long)|uniprotkb:HIV-1 Rev-binding protein 2(gene name synonym)|uniprotkb:Rev-interacting protein 1(gene name synonym)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:HRB2(gene name synonym)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym) psi-mi:zbp1_human(display_long)|uniprotkb:ZBP1(gene name)|psi-mi:ZBP1(display_short)|uniprotkb:C20orf183(gene name synonym)|uniprotkb:DLM1(gene name synonym)|uniprotkb:Tumor stroma and activated macrophage protein DLM-1(gene name synonym)|uniprotkb:DNA-dependent activator of IFN-regulatory factors(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Rebsamen et al. (2009) pubmed:19590578|imex:IM-13920|mint:MINT-7255923|doi:10.1038/embor.2009.109 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7092251|mint:MINT-7255958|imex:IM-13920-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000229214|ensembl:ENST00000438169|ensembl:ENSP00000411740|ensembl:ENSG00000111615(gene)|ensembl:ENST00000229214(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045171"(intercellular bridge)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|mint:Q13601|refseq:NP_008974.5|reactome:R-HSA-6790901|reactome:R-HSA-6791226|mint:MINT-7255960(identity) ensembl:ENSG00000124256(gene)|ensembl:ENST00000371173(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003692"(left-handed Z-DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070269"(pyroptosis)|go:"GO:2000659"(regulation of interleukin-1-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042361|interpro:IPR042371|mint:Q9H171|rcsb pdb:2L4M|rcsb pdb:2LNB|rcsb pdb:3EYI|rcsb pdb:4KA4|reactome:R-HSA-1606322|reactome:R-HSA-1606341|reactome:R-HSA-1810476|reactome:R-HSA-3134975|reactome:R-HSA-9679191|go:"GO:0050727"(regulation of inflammatory response)|refseq:NP_001310895.1|refseq:NP_001153889.1|refseq:NP_001153890.1|refseq:NP_110403.2|refseq:NP_001153891.1|dip:DIP-44121N|mint:MINT-7255966(identity) - - - figure legend:F1C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/08/08 2014/10/16 rogid:uBKNL/aw4wEssKJulbqQVWcH7ZI9606 rogid:Tu0wt0TeuDYF8q++Zl97sy6weZQ9606 intact-crc:2D3F63490799E5E6|rigid:pZBEf8nGi2WtEyiqgCr2X5MbbDE false tag:?-?(MINT-7255963) flag tag:?-?(MINT-7255967)|binding-associated region:196-216(MINT-7255972) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9H171 uniprotkb:Q9Y572 intact:EBI-6264672|ensembl:ENSP00000360215|uniprotkb:A2A2F7|uniprotkb:B3KVA1|uniprotkb:Q5JY39|uniprotkb:Q9BYW4|uniprotkb:F5GYT1 intact:EBI-298250|intact:EBI-358587|uniprotkb:C4AM87|uniprotkb:Q5J795|uniprotkb:Q5J796|uniprotkb:Q6P5Y1|uniprotkb:B4DJL9|ensembl:ENSP00000216274|ensembl:ENSP00000495490 psi-mi:zbp1_human(display_long)|uniprotkb:ZBP1(gene name)|psi-mi:ZBP1(display_short)|uniprotkb:C20orf183(gene name synonym)|uniprotkb:DLM1(gene name synonym)|uniprotkb:Tumor stroma and activated macrophage protein DLM-1(gene name synonym)|uniprotkb:DNA-dependent activator of IFN-regulatory factors(gene name synonym) psi-mi:ripk3_human(display_long)|uniprotkb:RIPK3(gene name)|psi-mi:RIPK3(display_short)|uniprotkb:RIP3(gene name synonym)|uniprotkb:RIP-like protein kinase 3(gene name synonym)|uniprotkb:Receptor-interacting protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Rebsamen et al. (2009) pubmed:19590578|imex:IM-13920|mint:MINT-7255923|doi:10.1038/embor.2009.109 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7092272|mint:MINT-7255975|imex:IM-13920-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000124256(gene)|ensembl:ENST00000371173(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003692"(left-handed Z-DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070269"(pyroptosis)|go:"GO:2000659"(regulation of interleukin-1-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042361|interpro:IPR042371|mint:Q9H171|rcsb pdb:2L4M|rcsb pdb:2LNB|rcsb pdb:3EYI|rcsb pdb:4KA4|reactome:R-HSA-1606322|reactome:R-HSA-1606341|reactome:R-HSA-1810476|reactome:R-HSA-3134975|reactome:R-HSA-9679191|go:"GO:0050727"(regulation of inflammatory response)|refseq:NP_001310895.1|refseq:NP_001153889.1|refseq:NP_001153890.1|refseq:NP_110403.2|refseq:NP_001153891.1|dip:DIP-44121N|mint:MINT-7255977(identity) refseq:NP_006862.2|dip:DIP-27519N|ensembl:ENSG00000129465(gene)|ensembl:ENSG00000285379(gene)|ensembl:ENST00000216274(transcript)|ensembl:ENST00000646516(transcript)|go:"GO:0001914"(regulation of T cell mediated cytotoxicity)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007165"(signal transduction)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046006"(regulation of activated T cell proliferation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070235"(regulation of activation-induced cell death of T cells)|go:"GO:0070266"(necroptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:0097528"(execution phase of necroptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000452"(regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR025735|mint:Q9Y572|rcsb pdb:5V7Z|rcsb pdb:5ZCK|rcsb pdb:7DAC|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-2562578|reactome:R-HSA-3295583|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-9013957|reactome:R-HSA-937041|reactome:R-HSA-9686347|rcsb pdb:7DA4|mint:MINT-7255981(identity) - - - figure legend:F1B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/08/08 2014/10/16 rogid:Tu0wt0TeuDYF8q++Zl97sy6weZQ9606 rogid:UgojU4aAUAG5RCZ55KR39AelO249606 intact-crc:358D32D4AE24AD5B|rigid:7sZIR8pj/sPVyAj4Dp2CVJJaLvY false tag:?-?(MINT-7255978) flag tag:?-?(MINT-7255982) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9H171 uniprotkb:Q9Y572 intact:EBI-6264672|ensembl:ENSP00000360215|uniprotkb:A2A2F7|uniprotkb:B3KVA1|uniprotkb:Q5JY39|uniprotkb:Q9BYW4|uniprotkb:F5GYT1 intact:EBI-298250|intact:EBI-358587|uniprotkb:C4AM87|uniprotkb:Q5J795|uniprotkb:Q5J796|uniprotkb:Q6P5Y1|uniprotkb:B4DJL9|ensembl:ENSP00000216274|ensembl:ENSP00000495490 psi-mi:zbp1_human(display_long)|uniprotkb:ZBP1(gene name)|psi-mi:ZBP1(display_short)|uniprotkb:C20orf183(gene name synonym)|uniprotkb:DLM1(gene name synonym)|uniprotkb:Tumor stroma and activated macrophage protein DLM-1(gene name synonym)|uniprotkb:DNA-dependent activator of IFN-regulatory factors(gene name synonym) psi-mi:ripk3_human(display_long)|uniprotkb:RIPK3(gene name)|psi-mi:RIPK3(display_short)|uniprotkb:RIP3(gene name synonym)|uniprotkb:RIP-like protein kinase 3(gene name synonym)|uniprotkb:Receptor-interacting protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Rebsamen et al. (2009) pubmed:19590578|imex:IM-13920|mint:MINT-7255923|doi:10.1038/embor.2009.109 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7092311|mint:MINT-7256003|imex:IM-13920-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000124256(gene)|ensembl:ENST00000371173(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003692"(left-handed Z-DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070269"(pyroptosis)|go:"GO:2000659"(regulation of interleukin-1-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042361|interpro:IPR042371|mint:Q9H171|rcsb pdb:2L4M|rcsb pdb:2LNB|rcsb pdb:3EYI|rcsb pdb:4KA4|reactome:R-HSA-1606322|reactome:R-HSA-1606341|reactome:R-HSA-1810476|reactome:R-HSA-3134975|reactome:R-HSA-9679191|go:"GO:0050727"(regulation of inflammatory response)|refseq:NP_001310895.1|refseq:NP_001153889.1|refseq:NP_001153890.1|refseq:NP_110403.2|refseq:NP_001153891.1|dip:DIP-44121N|mint:MINT-7256005(identity) refseq:NP_006862.2|dip:DIP-27519N|ensembl:ENSG00000129465(gene)|ensembl:ENSG00000285379(gene)|ensembl:ENST00000216274(transcript)|ensembl:ENST00000646516(transcript)|go:"GO:0001914"(regulation of T cell mediated cytotoxicity)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007165"(signal transduction)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046006"(regulation of activated T cell proliferation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070235"(regulation of activation-induced cell death of T cells)|go:"GO:0070266"(necroptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:0097528"(execution phase of necroptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000452"(regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR025735|mint:Q9Y572|rcsb pdb:5V7Z|rcsb pdb:5ZCK|rcsb pdb:7DAC|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-2562578|reactome:R-HSA-3295583|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-9013957|reactome:R-HSA-937041|reactome:R-HSA-9686347|rcsb pdb:7DA4|mint:MINT-7256009(identity) - - - comment:homomint|comment:mint|figure legend:F1F F3B F2B F2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/08/08 2014/10/16 rogid:Tu0wt0TeuDYF8q++Zl97sy6weZQ9606 rogid:UgojU4aAUAG5RCZ55KR39AelO249606 intact-crc:D8E06AADEEE35E99|rigid:7sZIR8pj/sPVyAj4Dp2CVJJaLvY false tag:?-?(MINT-7256006) flag tag:?-?(MINT-7256012) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y572 uniprotkb:Q9H171 intact:EBI-298250|intact:EBI-358587|uniprotkb:C4AM87|uniprotkb:Q5J795|uniprotkb:Q5J796|uniprotkb:Q6P5Y1|uniprotkb:B4DJL9|ensembl:ENSP00000216274|ensembl:ENSP00000495490 intact:EBI-6264672|ensembl:ENSP00000360215|uniprotkb:A2A2F7|uniprotkb:B3KVA1|uniprotkb:Q5JY39|uniprotkb:Q9BYW4|uniprotkb:F5GYT1 psi-mi:ripk3_human(display_long)|uniprotkb:RIPK3(gene name)|psi-mi:RIPK3(display_short)|uniprotkb:RIP3(gene name synonym)|uniprotkb:RIP-like protein kinase 3(gene name synonym)|uniprotkb:Receptor-interacting protein 3(gene name synonym) psi-mi:zbp1_human(display_long)|uniprotkb:ZBP1(gene name)|psi-mi:ZBP1(display_short)|uniprotkb:C20orf183(gene name synonym)|uniprotkb:DLM1(gene name synonym)|uniprotkb:Tumor stroma and activated macrophage protein DLM-1(gene name synonym)|uniprotkb:DNA-dependent activator of IFN-regulatory factors(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Rebsamen et al. (2009) pubmed:19590578|imex:IM-13920|mint:MINT-7255923|doi:10.1038/embor.2009.109 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7092344|mint:MINT-7256020|imex:IM-13920-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006862.2|dip:DIP-27519N|ensembl:ENSG00000129465(gene)|ensembl:ENSG00000285379(gene)|ensembl:ENST00000216274(transcript)|ensembl:ENST00000646516(transcript)|go:"GO:0001914"(regulation of T cell mediated cytotoxicity)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007165"(signal transduction)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046006"(regulation of activated T cell proliferation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070235"(regulation of activation-induced cell death of T cells)|go:"GO:0070266"(necroptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:0097528"(execution phase of necroptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000452"(regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR025735|mint:Q9Y572|rcsb pdb:5V7Z|rcsb pdb:5ZCK|rcsb pdb:7DAC|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-2562578|reactome:R-HSA-3295583|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-9013957|reactome:R-HSA-937041|reactome:R-HSA-9686347|rcsb pdb:7DA4|mint:MINT-7256022(identity) ensembl:ENSG00000124256(gene)|ensembl:ENST00000371173(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003692"(left-handed Z-DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070269"(pyroptosis)|go:"GO:2000659"(regulation of interleukin-1-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042361|interpro:IPR042371|mint:Q9H171|rcsb pdb:2L4M|rcsb pdb:2LNB|rcsb pdb:3EYI|rcsb pdb:4KA4|reactome:R-HSA-1606322|reactome:R-HSA-1606341|reactome:R-HSA-1810476|reactome:R-HSA-3134975|reactome:R-HSA-9679191|go:"GO:0050727"(regulation of inflammatory response)|refseq:NP_001310895.1|refseq:NP_001153889.1|refseq:NP_001153890.1|refseq:NP_110403.2|refseq:NP_001153891.1|dip:DIP-44121N|mint:MINT-7256026(identity) - - - figure legend:F1I|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/08/08 2014/10/16 rogid:UgojU4aAUAG5RCZ55KR39AelO249606 rogid:Tu0wt0TeuDYF8q++Zl97sy6weZQ9606 intact-crc:424025108D1E9093|rigid:7sZIR8pj/sPVyAj4Dp2CVJJaLvY false tag:?-?(MINT-7256023) flag tag:?-?(MINT-7256027)|binding-associated region:196-216(MINT-7256033) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:A8E1H1 uniprotkb:Q9Y572 intact:EBI-6151824 intact:EBI-298250|intact:EBI-358587|uniprotkb:C4AM87|uniprotkb:Q5J795|uniprotkb:Q5J796|uniprotkb:Q6P5Y1|uniprotkb:B4DJL9|ensembl:ENSP00000216274|ensembl:ENSP00000495490 psi-mi:a8e1h1_muhvk(display_long)|uniprotkb:M45(gene name)|psi-mi:M45(display_short)|uniprotkb:RIR1(gene name synonym) psi-mi:ripk3_human(display_long)|uniprotkb:RIPK3(gene name)|psi-mi:RIPK3(display_short)|uniprotkb:RIP3(gene name synonym)|uniprotkb:RIP-like protein kinase 3(gene name synonym)|uniprotkb:Receptor-interacting protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Rebsamen et al. (2009) pubmed:19590578|imex:IM-13920|mint:MINT-7255923|doi:10.1038/embor.2009.109 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7092386|mint:MINT-7256069|imex:IM-13920-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:A8E1H1|interpro:IPR034716|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR025735|interpro:IPR039718|go:"GO:0006260"(DNA replication)|go:"GO:0030430"(host cell cytoplasm)|mint:MINT-7256071(identity) refseq:NP_006862.2|dip:DIP-27519N|ensembl:ENSG00000129465(gene)|ensembl:ENSG00000285379(gene)|ensembl:ENST00000216274(transcript)|ensembl:ENST00000646516(transcript)|go:"GO:0001914"(regulation of T cell mediated cytotoxicity)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007165"(signal transduction)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046006"(regulation of activated T cell proliferation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070235"(regulation of activation-induced cell death of T cells)|go:"GO:0070266"(necroptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:0097528"(execution phase of necroptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000452"(regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR025735|mint:Q9Y572|rcsb pdb:5V7Z|rcsb pdb:5ZCK|rcsb pdb:7DAC|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-2562578|reactome:R-HSA-3295583|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-9013957|reactome:R-HSA-937041|reactome:R-HSA-9686347|rcsb pdb:7DA4|mint:MINT-7256077(identity) - - - figure legend:F4A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/08/08 2014/10/16 rogid:2O/mT6rYOIr8HVkTPHmcognnecs69156 rogid:UgojU4aAUAG5RCZ55KR39AelO249606 intact-crc:53AB5E7526FD9C02|rigid:ZCKP8OHGmkZf9+8efZoDChgtYnM false binding-associated region:1-277(MINT-7256072)|tag:?-?(MINT-7256074) flag tag:?-?(MINT-7256078) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:A8E1H1 uniprotkb:Q9H171 intact:EBI-6151824 intact:EBI-6264672|ensembl:ENSP00000360215|uniprotkb:A2A2F7|uniprotkb:B3KVA1|uniprotkb:Q5JY39|uniprotkb:Q9BYW4|uniprotkb:F5GYT1 psi-mi:a8e1h1_muhvk(display_long)|uniprotkb:M45(gene name)|psi-mi:M45(display_short)|uniprotkb:RIR1(gene name synonym) psi-mi:zbp1_human(display_long)|uniprotkb:ZBP1(gene name)|psi-mi:ZBP1(display_short)|uniprotkb:C20orf183(gene name synonym)|uniprotkb:DLM1(gene name synonym)|uniprotkb:Tumor stroma and activated macrophage protein DLM-1(gene name synonym)|uniprotkb:DNA-dependent activator of IFN-regulatory factors(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Rebsamen et al. (2009) pubmed:19590578|imex:IM-13920|mint:MINT-7255923|doi:10.1038/embor.2009.109 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7092365|mint:MINT-7256038|imex:IM-13920-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:A8E1H1|interpro:IPR034716|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR025735|interpro:IPR039718|go:"GO:0006260"(DNA replication)|go:"GO:0030430"(host cell cytoplasm)|mint:MINT-7256040(identity) ensembl:ENSG00000124256(gene)|ensembl:ENST00000371173(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003692"(left-handed Z-DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070269"(pyroptosis)|go:"GO:2000659"(regulation of interleukin-1-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042361|interpro:IPR042371|mint:Q9H171|rcsb pdb:2L4M|rcsb pdb:2LNB|rcsb pdb:3EYI|rcsb pdb:4KA4|reactome:R-HSA-1606322|reactome:R-HSA-1606341|reactome:R-HSA-1810476|reactome:R-HSA-3134975|reactome:R-HSA-9679191|go:"GO:0050727"(regulation of inflammatory response)|refseq:NP_001310895.1|refseq:NP_001153889.1|refseq:NP_001153890.1|refseq:NP_110403.2|refseq:NP_001153891.1|dip:DIP-44121N|mint:MINT-7256044(identity) - - - figure legend:F4A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/08/08 2014/10/16 rogid:2O/mT6rYOIr8HVkTPHmcognnecs69156 rogid:Tu0wt0TeuDYF8q++Zl97sy6weZQ9606 intact-crc:E1F9CFED2A623CA2|rigid:xMaR33Ov8ihvTUkqEQnGd8d3FnE false binding-associated region:1-277(MINT-7256050)|tag:?-?(MINT-7256041) flag tag:?-?(MINT-7256045) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)