#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P00711 uniprotkb:Q765B0 intact:EBI-7080486|intact:MINT-1487560|uniprotkb:Q95NE4|uniprotkb:Q3T111 intact:EBI-7080513|intact:MINT-1487550 psi-mi:lalba_bovin(display_long)|uniprotkb:LALBA(gene name)|psi-mi:LALBA(display_short)|uniprotkb:ALACTA(gene name synonym)|uniprotkb:Lactose synthase B protein(gene name synonym) psi-mi:q765b0_9gamm(display_long)|uniprotkb:fklB(gene name)|psi-mi:fklB(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Budiman et al. (2009) pubmed:19558490|mint:MINT-7136112|mint:fj-09-0517.r1 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:117911(shewanella sp. sib1)|taxid:117911(Shewanella sp. SIB1) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7080526|mint:MINT-7136140 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P00711|go:"GO:0004461"(lactose synthase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005989"(lactose biosynthetic process)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0042802"(identical protein binding)|go:"GO:1903494"(response to dehydroepiandrosterone)|go:"GO:1903496"(response to 11-deoxycorticosterone)|rcsb pdb:1F6R|rcsb pdb:1F6S|rcsb pdb:1HFZ|rcsb pdb:2G4N|rcsb pdb:6IP9|interpro:IPR019799|interpro:IPR023346|refseq:NP_776803.1|interpro:IPR000545(Lactalbumin)|interpro:IPR001916(Glycoside hydrolase, family 22)|mint:MINT-7136178(identity) mint:Q765B0|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|rcsb pdb:3B09|interpro:IPR000774(Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR036944|mint:MINT-7136142(identity) - comment:mint|comment:homomint|function:Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins comment:mint figure legend:F5|comment:mint|comment:Kd value for binding of reduced α-lactalbumin to NNC-FKBP22 was determined to be 42.5±2.1 μM. taxid:-1(in vitro)|taxid:-1(In vitro) kd:6.5x10^-6(molar) 2009/05/27 2014/10/16 rogid:jEnBQQgOzSEaNmxGJLAV+KkbnGs9913 rogid:dWcVCTSFCS500AimUM+Iwp29fk4117911 intact-crc:27D937F8F4BEF497|rigid:+jDARCY4+6K5X8cpEWVpIartt2A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)