#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P49427	uniprotkb:P67870	intact:EBI-975634|ensembl:ENSP00000215574|uniprotkb:A8K689	intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9	psi-mi:ub2r1_human(display_long)|uniprotkb:Ubiquitin-protein ligase R1(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-32 kDa complementing(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-CDC34(gene name synonym)|uniprotkb:CDC34(gene name)|psi-mi:CDC34(display_short)|uniprotkb:UBE2R1(gene name synonym)|uniprotkb:UBCH3(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme R1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme R1(gene name synonym)	psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339181|imex:IM-11696-583	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070848"(response to growth factor)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090261"(positive regulation of inclusion body assembly)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2OB4|rcsb pdb:3RZ3|rcsb pdb:4MDK|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-983168|ensembl:ENSG00000099804(gene)|ensembl:ENST00000215574(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:NP_004350.1|dip:DIP-37783N	ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:iOYLaiXBmINnd0daIWCr5KVungo9606	rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606	intact-crc:C93F6CBEEC50C9A6|rigid:TGvdo4PR4W85bEVDPd7xKYzNPYg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y5L4	uniprotkb:P49427	intact:EBI-1057344|uniprotkb:P62206|uniprotkb:Q9UHL8|uniprotkb:Q9WTL1|ensembl:ENSP00000215570	intact:EBI-975634|ensembl:ENSP00000215574|uniprotkb:A8K689	psi-mi:tim13_human(display_long)|uniprotkb:TIMM13(gene name)|psi-mi:TIMM13(display_short)|uniprotkb:TIM13B(gene name synonym)|uniprotkb:TIMM13A(gene name synonym)|uniprotkb:TIMM13B(gene name synonym)	psi-mi:ub2r1_human(display_long)|uniprotkb:Ubiquitin-protein ligase R1(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-32 kDa complementing(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-CDC34(gene name synonym)|uniprotkb:CDC34(gene name)|psi-mi:CDC34(display_short)|uniprotkb:UBE2R1(gene name synonym)|uniprotkb:UBCH3(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme R1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme R1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339184|imex:IM-11696-584	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036590.1|ensembl:ENSG00000099800(gene)|ensembl:ENST00000215570(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:Q9Y5L4|reactome:R-HSA-1268020	go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070848"(response to growth factor)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090261"(positive regulation of inclusion body assembly)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2OB4|rcsb pdb:3RZ3|rcsb pdb:4MDK|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-983168|ensembl:ENSG00000099804(gene)|ensembl:ENST00000215574(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:NP_004350.1|dip:DIP-37783N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:kFNYBvKwUM0JECXq9FjvYv55JAM9606	rogid:iOYLaiXBmINnd0daIWCr5KVungo9606	intact-crc:6829B3EAA588C921|rigid:W67kTkCOnQU1DfNfqJF/e6vGAfY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49427	uniprotkb:Q9UBQ5	intact:EBI-975634|ensembl:ENSP00000215574|uniprotkb:A8K689	intact:EBI-354344|uniprotkb:Q96IQ0|uniprotkb:Q9Y6D1|intact:EBI-2339187|uniprotkb:A8K0I9|ensembl:ENSP00000248342|ensembl:ENSP00000489438|uniprotkb:B7ZAM9	psi-mi:ub2r1_human(display_long)|uniprotkb:Ubiquitin-protein ligase R1(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-32 kDa complementing(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-CDC34(gene name synonym)|uniprotkb:CDC34(gene name)|psi-mi:CDC34(display_short)|uniprotkb:UBE2R1(gene name synonym)|uniprotkb:UBCH3(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme R1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme R1(gene name synonym)	psi-mi:eif3k_human(display_long)|uniprotkb:MSTP001(orf name)|uniprotkb:PTD001(orf name)|uniprotkb:HSPC029(orf name)|uniprotkb:EIF3K(gene name)|psi-mi:EIF3K(display_short)|uniprotkb:ARG134(orf name)|uniprotkb:EIF3S12(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 12(gene name synonym)|uniprotkb:eIF-3 p25(gene name synonym)|uniprotkb:eIF-3 p28(gene name synonym)|uniprotkb:Muscle-specific gene M9 protein(gene name synonym)|uniprotkb:PLAC-24(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339191|imex:IM-11696-582	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070848"(response to growth factor)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090261"(positive regulation of inclusion body assembly)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2OB4|rcsb pdb:3RZ3|rcsb pdb:4MDK|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-983168|ensembl:ENSG00000099804(gene)|ensembl:ENST00000215574(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:NP_004350.1|dip:DIP-37783N	refseq:NP_037366.1|ensembl:ENSG00000282986(gene)|ensembl:ENST00000248342(transcript)|ensembl:ENST00000635567(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|ensembl:ENSG00000178982(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR009374(Translation initiation factor 3, subunit 12, eukaryotic)|interpro:IPR016020(Translation initiation factor 3, subunit 12, N-terminal, eukaryotic)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033464|interpro:IPR036388|interpro:IPR036390|mint:Q9UBQ5|rcsb pdb:1RZ4|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-32880N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:iOYLaiXBmINnd0daIWCr5KVungo9606	rogid:sle5eYxV0F37AzixzoNY4Jm6Loo9606	intact-crc:BFB720F068838534|rigid:oBvW6Nu9MDm8AEZdxmEasNe/4yU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49427	uniprotkb:Q9P0S9	intact:EBI-975634|ensembl:ENSP00000215574|uniprotkb:A8K689	intact:EBI-2339195|uniprotkb:Q5T4I6|ensembl:ENSP00000229563|ensembl:ENSP00000444561|ensembl:ENSP00000495127|ensembl:ENSP00000495742	psi-mi:ub2r1_human(display_long)|uniprotkb:Ubiquitin-protein ligase R1(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-32 kDa complementing(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-CDC34(gene name synonym)|uniprotkb:CDC34(gene name)|psi-mi:CDC34(display_short)|uniprotkb:UBE2R1(gene name synonym)|uniprotkb:UBCH3(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme R1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme R1(gene name synonym)	psi-mi:tm14c_human(display_long)|uniprotkb:TMEM14C(gene name)|psi-mi:TMEM14C(display_short)|uniprotkb:C6orf53(gene name synonym)|uniprotkb:HSPC194(orf name)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339194|imex:IM-11696-585	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070848"(response to growth factor)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090261"(positive regulation of inclusion body assembly)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2OB4|rcsb pdb:3RZ3|rcsb pdb:4MDK|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-983168|ensembl:ENSG00000099804(gene)|ensembl:ENST00000215574(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:NP_004350.1|dip:DIP-37783N	refseq:NP_001158730.1|refseq:NP_057546.1|ensembl:ENSG00000111843(gene)|ensembl:ENSG00000284936(gene)|ensembl:ENST00000229563(transcript)|ensembl:ENST00000541412(transcript)|ensembl:ENST00000642513(transcript)|ensembl:ENST00000643226(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0070453"(regulation of heme biosynthetic process)|interpro:IPR005349(Protein of unknown function UPF0136, Transmembrane)|interpro:IPR044890|mint:Q9P0S9|rcsb pdb:2LOS	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:iOYLaiXBmINnd0daIWCr5KVungo9606	rogid:2wqwjWske9Rf+9F2lDMe35p5Tr89606	intact-crc:4F19F18D81CFDBD9|rigid:dGKzO/XSpF6x9iLSzQpWkGfNDPA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61086	uniprotkb:Q8IUQ4	intact:EBI-473850|uniprotkb:A6NJC1|uniprotkb:O54806|uniprotkb:P27924|uniprotkb:Q16721|uniprotkb:Q9CVV9|uniprotkb:Q9Y2D3|uniprotkb:B2RDF8|uniprotkb:A8K5Y9|uniprotkb:C9JGP1|ensembl:ENSP00000261427	intact:EBI-747107|uniprotkb:O43269|uniprotkb:Q49A58|uniprotkb:A0FKF3|uniprotkb:Q92880|ensembl:ENSP00000369343|ensembl:ENSP00000378214|ensembl:ENSP00000456421	psi-mi:ube2k_human(display_long)|uniprotkb:HIP2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-25 kDa(gene name synonym)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2(gene name synonym)|uniprotkb:UBE2K(gene name)|psi-mi:UBE2K(display_short)|uniprotkb:LIG(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme K(gene name synonym)	psi-mi:siah1_human(display_long)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339201|imex:IM-11696-586	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001104582.1|refseq:NP_001104583.1|refseq:NP_005330.1|dip:DIP-32524N|ensembl:ENSG00000078140(gene)|ensembl:ENST00000261427(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|interpro:IPR042599|rcsb pdb:1YLA|rcsb pdb:2O25|rcsb pdb:3E46|rcsb pdb:3F92|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:5DFL|rcsb pdb:6IF1|rcsb pdb:6JB6|rcsb pdb:6JB7|reactome:R-HSA-8866652|reactome:R-HSA-936440|reactome:R-HSA-983168	refseq:XP_006721309.1|refseq:NP_001006611.1|refseq:NP_003022.3|refseq:XP_011521581.1|ensembl:ENST00000380006(transcript)|ensembl:ENST00000394725(transcript)|ensembl:ENST00000568007(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|mint:Q8IUQ4|rcsb pdb:2A25|rcsb pdb:4C9Z|rcsb pdb:4CA1|rcsb pdb:4I7B|rcsb pdb:4I7C|rcsb pdb:4I7D|rcsb pdb:4X3G|rcsb pdb:5WZZ|reactome:R-HSA-373752|reactome:R-HSA-977225|reactome:R-HSA-983168|ensembl:ENSG00000196470(gene)|dip:DIP-35684N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:TTxSiXJ5fNdGUeuzYlPvDl8W7eg9606	rogid:O6+z1g9K1ij87Xgo5/Ykl5Q3vUQ9606	intact-crc:768418986F4E641E|rigid:Jl42MyqKmkE1FJGjKDaaG+VLZOc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61086	uniprotkb:Q8WVD3	intact:EBI-473850|uniprotkb:A6NJC1|uniprotkb:O54806|uniprotkb:P27924|uniprotkb:Q16721|uniprotkb:Q9CVV9|uniprotkb:Q9Y2D3|uniprotkb:B2RDF8|uniprotkb:A8K5Y9|uniprotkb:C9JGP1|ensembl:ENSP00000261427	intact:EBI-749039|uniprotkb:Q9H8K2|uniprotkb:Q9UF87|uniprotkb:Q9UKI6|uniprotkb:B2RE17|ensembl:ENSP00000261593	psi-mi:ube2k_human(display_long)|uniprotkb:HIP2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-25 kDa(gene name synonym)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2(gene name synonym)|uniprotkb:UBE2K(gene name)|psi-mi:UBE2K(display_short)|uniprotkb:LIG(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme K(gene name synonym)	psi-mi:rn138_human(display_long)|uniprotkb:RING finger protein 138(gene name synonym)|uniprotkb:Nemo-like kinase-associated RING finger protein(gene name synonym)|uniprotkb:RNF138(gene name)|psi-mi:RNF138(display_short)|uniprotkb:NARF(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF138(gene name synonym)|uniprotkb:HSD-4(orf name)|uniprotkb:HSD4(orf name)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339204|imex:IM-11696-587	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001104582.1|refseq:NP_001104583.1|refseq:NP_005330.1|dip:DIP-32524N|ensembl:ENSG00000078140(gene)|ensembl:ENST00000261427(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|interpro:IPR042599|rcsb pdb:1YLA|rcsb pdb:2O25|rcsb pdb:3E46|rcsb pdb:3F92|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:5DFL|rcsb pdb:6IF1|rcsb pdb:6JB6|rcsb pdb:6JB7|reactome:R-HSA-8866652|reactome:R-HSA-936440|reactome:R-HSA-983168	refseq:NP_057355.2|refseq:NP_937761.1|refseq:NP_001178253.2|refseq:XP_005258343.1|ensembl:ENSG00000134758(gene)|ensembl:ENST00000261593(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034734|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:TTxSiXJ5fNdGUeuzYlPvDl8W7eg9606	rogid:HhGscRenFoqXTiZxHR62E4wcIo09606	intact-crc:D8E9CCB72CECBF47|rigid:5aSF7ELJ7U9OrdzUzwzQbkPk8iM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EQ8	uniprotkb:P61086	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	intact:EBI-473850|uniprotkb:A6NJC1|uniprotkb:O54806|uniprotkb:P27924|uniprotkb:Q16721|uniprotkb:Q9CVV9|uniprotkb:Q9Y2D3|uniprotkb:B2RDF8|uniprotkb:A8K5Y9|uniprotkb:C9JGP1|ensembl:ENSP00000261427	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:ube2k_human(display_long)|uniprotkb:HIP2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-25 kDa(gene name synonym)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2(gene name synonym)|uniprotkb:UBE2K(gene name)|psi-mi:UBE2K(display_short)|uniprotkb:LIG(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme K(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339207|imex:IM-11696-588	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	refseq:NP_001104582.1|refseq:NP_001104583.1|refseq:NP_005330.1|dip:DIP-32524N|ensembl:ENSG00000078140(gene)|ensembl:ENST00000261427(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|interpro:IPR042599|rcsb pdb:1YLA|rcsb pdb:2O25|rcsb pdb:3E46|rcsb pdb:3F92|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:5DFL|rcsb pdb:6IF1|rcsb pdb:6JB6|rcsb pdb:6JB7|reactome:R-HSA-8866652|reactome:R-HSA-936440|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	rogid:TTxSiXJ5fNdGUeuzYlPvDl8W7eg9606	intact-crc:3A278C6C66B198F0|rigid:jOyCUl17cno/wWmsKRcefdFgqcw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:P24539	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-1044810|uniprotkb:Q9BQ68|uniprotkb:Q9BRU8|ensembl:ENSP00000358737	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:at5f1_human(display_long)|uniprotkb:ATP5PB(gene name)|psi-mi:ATP5PB(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:"ATP synthase proton-transporting mitochondrial F(0) complex subunit B1"(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:ATP5F1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339215|imex:IM-11696-589	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_001679.2|ensembl:ENSG00000116459(gene)|ensembl:ENST00000369722(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0021762"(substantia nigra development)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:P24539|reactome:R-HSA-163210|reactome:R-HSA-8949613|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:n1HuorsLzONcID7ccOL9qEsODLE9606	intact-crc:107BE0D8E37C6F0B|rigid:jWmPy/Xty9SIdqZOa6rdn4T2aKk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q08426	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-2339219|uniprotkb:Q58EZ5|uniprotkb:A8K6Y3|uniprotkb:B4DWG3|uniprotkb:D3DNU0|ensembl:ENSP00000231887	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:echp_human(display_long)|uniprotkb:EHHADH(gene name)|psi-mi:EHHADH(display_short)|uniprotkb:ECHD(gene name synonym)|uniprotkb:L-bifunctional protein(gene name synonym)|uniprotkb:Multifunctional enzyme 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339218|imex:IM-11696-590	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_001159887.1|refseq:NP_001957.2|refseq:XP_011510819.1|ensembl:ENSG00000113790(gene)|ensembl:ENST00000231887(transcript)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0004165"("delta(3)-delta(2)-enoyl-CoA isomerase activity")|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0016863"(intramolecular oxidoreductase activity, transposing C=C bonds)|go:"GO:0019899"(enzyme binding)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|reactome:R-HSA-390247|reactome:R-HSA-9033241	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:wLWtQcRIDop9pL/IORzyGmnsf+g9606	intact-crc:81C980C994A22491|rigid:o8/Mbis5YHDlJ/9+hlfIwrnFt3s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:P06733	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339226|imex:IM-11696-591	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:6BF88780017DE29D|rigid:r6fbLGnSgScwzxuN02I75ZouoTQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:P14324	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-948245|ensembl:ENSP00000349078|ensembl:ENSP00000357340|uniprotkb:Q96G29|uniprotkb:D3DV91|uniprotkb:E9PCI9	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:fpps_human(display_long)|uniprotkb:Farnesyl diphosphate synthase(gene name synonym)|uniprotkb:FDPS(gene name)|psi-mi:FDPS(display_short)|uniprotkb:FPS(gene name synonym)|uniprotkb:KIAA1293(gene name synonym)|uniprotkb:"(2E,6E)-farnesyl diphosphate synthase"(gene name synonym)|uniprotkb:Dimethylallyltranstransferase(gene name synonym)|uniprotkb:Geranyltranstransferase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339229|imex:IM-11696-592	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	ensembl:ENSG00000160752(gene)|ensembl:ENST00000356657(transcript)|ensembl:ENST00000368356(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004161"(dimethylallyltranstransferase activity)|go:"GO:0004337"(geranyltranstransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0033384"(geranyl diphosphate biosynthetic process)|go:"GO:0045337"(farnesyl diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000092(Polyprenyl synthetase)|interpro:IPR008949(Terpenoid synthase)|interpro:IPR033749|go:"GO:0005654"(nucleoplasm)|rcsb pdb:1YQ7|rcsb pdb:1ZW5|rcsb pdb:2F7M|rcsb pdb:2F89|rcsb pdb:2F8C|rcsb pdb:2F8Z|rcsb pdb:2F92|rcsb pdb:2F94|rcsb pdb:2F9K|rcsb pdb:2OPM|rcsb pdb:2OPN|rcsb pdb:2QIS|rcsb pdb:2RAH|rcsb pdb:2VF6|rcsb pdb:3B7L|rcsb pdb:3CP6|rcsb pdb:3N1V|rcsb pdb:3N1W|rcsb pdb:3N3L|rcsb pdb:3N45|rcsb pdb:3N46|rcsb pdb:1YV5|rcsb pdb:3N49|rcsb pdb:3N5H|rcsb pdb:3N5J|rcsb pdb:3N6K|rcsb pdb:3RYE|rcsb pdb:3S4J|rcsb pdb:4DEM|rcsb pdb:4GA3|rcsb pdb:4H5D|rcsb pdb:4H5E|rcsb pdb:4JVJ|rcsb pdb:4KFA|rcsb pdb:4KPD|rcsb pdb:4KPJ|rcsb pdb:4KQ5|rcsb pdb:4KQS|rcsb pdb:4KQU|rcsb pdb:4L2X|rcsb pdb:4LFV|rcsb pdb:4LPG|rcsb pdb:4LPH|rcsb pdb:4N1Z|rcsb pdb:4N9U|rcsb pdb:4NFI|rcsb pdb:4NFJ|rcsb pdb:4NFK|rcsb pdb:4NG6|rcsb pdb:4NKE|rcsb pdb:4NKF|rcsb pdb:4NUA|rcsb pdb:4OGU|rcsb pdb:4P0V|rcsb pdb:4P0W|rcsb pdb:4P0X|rcsb pdb:4PVX|rcsb pdb:4PVY|rcsb pdb:4H5C|rcsb pdb:4Q23|rcsb pdb:4QPF|rcsb pdb:4QXS|rcsb pdb:4RXA|rcsb pdb:4XQR|rcsb pdb:4XQS|rcsb pdb:4XQT|reactome:R-HSA-2426168|rcsb pdb:5CG6|rcsb pdb:5DGM|rcsb pdb:5CG5|rcsb pdb:5DGN|rcsb pdb:5DGS|rcsb pdb:5DIQ|rcsb pdb:5DJP|rcsb pdb:5DJR|rcsb pdb:5DJV|rcsb pdb:5JA0|rcsb pdb:5JUZ|rcsb pdb:5JV0|rcsb pdb:5JV1|rcsb pdb:5JV2|rcsb pdb:5KSX|rcsb pdb:5YGI|rcsb pdb:6N7Y|rcsb pdb:6N7Z|rcsb pdb:6N82|rcsb pdb:6N83|rcsb pdb:6OAG|rcsb pdb:6OAH|reactome:R-HSA-191273|refseq:NP_001129293.1|refseq:NP_001129294.1|refseq:NP_001229753.1|refseq:NP_001229754.1|refseq:NP_001995.1|refseq:XP_005245019.1|refseq:XP_005245020.1|dip:DIP-50059N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:cLrS58XE4dKJiiK96hQt7JPO5T89606	intact-crc:486D3ECF3A83922D|rigid:/iLC16RxPf06gxmeHmd+dbK3aFQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:P02792	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-713279|uniprotkb:Q7Z2W1|uniprotkb:Q9BTZ8|ensembl:ENSP00000366525|uniprotkb:B2R4B9|uniprotkb:Q6IBT7|uniprotkb:Q86WI9|uniprotkb:Q8WU07|uniprotkb:Q96AU9|uniprotkb:Q96CU0	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:fril_human(display_long)|uniprotkb:FTL(gene name)|psi-mi:FTL(display_short)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339232|imex:IM-11696-593	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_000137.2|ensembl:ENSG00000087086(gene)|ensembl:ENST00000331825(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0044754"(autolysosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|mint:P02792|rcsb pdb:2FFX|rcsb pdb:2FG4|rcsb pdb:2FG8|rcsb pdb:3KXU|rcsb pdb:4V6B|rcsb pdb:5LG8|rcsb pdb:6TR9|rcsb pdb:6TS0|rcsb pdb:6TS1|rcsb pdb:6TSA|rcsb pdb:6TSF|rcsb pdb:6TSJ|rcsb pdb:6WX6|reactome:R-HSA-3000480|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-917937|dip:DIP-31248N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:+mbnoETQ9TuBZg8Gc09nwAjwKTE9606	intact-crc:E153F19BC6628F79|rigid:C66sbKjiXyxwmcAO5CltX/PYqvg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P05783	uniprotkb:Q99816	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487|ensembl:ENSP00000373489	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339235|imex:IM-11696-594	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005912"(adherens junction)|go:"GO:0007049"(cell cycle)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009750"(response to fructose)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045095"(keratin filament)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0072497"(mesenchymal stem cell differentiation)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1902488"(cholangiocyte apoptotic process)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR027695|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|ensembl:ENSG00000111057(gene)|ensembl:ENST00000388835(transcript)|ensembl:ENST00000388837(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|refseq:NP_000215.1|refseq:NP_954657.1|dip:DIP-633N	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	intact-crc:2A3F02D225EEE29F|rigid:SNdTAHCvsxkfic9FBxLFTb2EOgU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13415	uniprotkb:Q99816	intact:EBI-374847|uniprotkb:Q13471|uniprotkb:Q5T0F5|ensembl:ENSP00000360621|ensembl:ENSP00000360623|uniprotkb:D3DQ34	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	psi-mi:orc1_human(display_long)|uniprotkb:ORC1(gene name)|psi-mi:ORC1(display_short)|uniprotkb:ORC1L(gene name synonym)|uniprotkb:PARC1(gene name synonym)|uniprotkb:Replication control protein 1(gene name synonym)	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339238|imex:IM-11696-595	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000085840(gene)|ensembl:ENST00000371566(transcript)|ensembl:ENST00000371568(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000808"(origin recognition complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|mint:Q13415|rcsb pdb:5UJ7|rcsb pdb:5UJM|rcsb pdb:6P3W|rcsb pdb:7CTF|rcsb pdb:7CTG|rcsb pdb:7JPO|rcsb pdb:7JPP|rcsb pdb:7JPR|rcsb pdb:7JPS|reactome:R-HSA-113507|reactome:R-HSA-176187|reactome:R-HSA-68616|reactome:R-HSA-68689|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69205|refseq:NP_001177747.1|refseq:NP_001177748.1|refseq:NP_004144.2|dip:DIP-29688N	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:I6knhXEuT6YwDSFoH5oLh8rpCT89606	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	intact-crc:6C7C7B5C4FC8E3BA|rigid:Zza7rCy66uYfmcPL2ICfJOwyB/E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P31350	uniprotkb:Q99816	intact:EBI-2339245|uniprotkb:B2R9B5|uniprotkb:Q5WRU7|uniprotkb:J3KP43|intact:EBI-10973436|ensembl:ENSP00000302955|ensembl:ENSP00000493399	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	psi-mi:rir2_human(display_long)|uniprotkb:RRM2(gene name)|psi-mi:RRM2(display_short)|uniprotkb:RR2(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit(gene name synonym)|uniprotkb:Ribonucleotide reductase small chain(gene name synonym)	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339244|imex:IM-11696-597	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001025.1|refseq:NP_001159403.1|dip:DIP-24232N|ensembl:ENSG00000171848(gene)|ensembl:ENST00000304567(transcript)|ensembl:ENST00000641198(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0008199"(ferric iron binding)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:2UW2|rcsb pdb:3OLJ|rcsb pdb:3VPM|rcsb pdb:3VPN|rcsb pdb:3VPO|reactome:R-HSA-499943|reactome:R-HSA-69205|reactome:R-HSA-8953750	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vkkD9wGSPnsXX89dIQ53fhLD7uI9606	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	intact-crc:9CFEDF760263C7B7|rigid:Vh2+bOgC/XhTzyRJLF9RV+XW+3k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49005	uniprotkb:Q99816	intact:EBI-372354|ensembl:ENSP00000386105|ensembl:ENSP00000395231|ensembl:ENSP00000480186|uniprotkb:A4D2J4|uniprotkb:B2R5S4	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	psi-mi:dpod2_human(display_long)|uniprotkb:POLD2(gene name)|psi-mi:POLD2(display_short)|uniprotkb:DNA polymerase delta subunit p50(gene name synonym)	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339241|imex:IM-11696-596	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120690.1|ensembl:ENSG00000106628(gene)|ensembl:ENST00000406581(transcript)|ensembl:ENST00000452185(transcript)|ensembl:ENST00000610533(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0016035"(zeta DNA polymerase complex)|go:"GO:0042575"(DNA polymerase complex)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR024826|interpro:IPR040663|interpro:IPR041863|mint:P49005|rcsb pdb:3E0J|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|reactome:R-HSA-110314|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|refseq:NP_001243808.1|refseq:NP_006221.2	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:B8QUTohwg0iz3s5wdSdmcTGa28I9606	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	intact-crc:BABF2C2CFCD3277D|rigid:UsWnO7hk4NrlPH/2wznR7xIdenI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q99816	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339256|imex:IM-11696-599	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	intact-crc:60721EBA0B8B1C1C|rigid:I15mtlT8uWcXT/Vl3bELJs61/Bs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q8TAQ2	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-357418|ensembl:ENSP00000267064|uniprotkb:Q92923|uniprotkb:Q96E12|uniprotkb:Q96GY4|intact:EBI-1759986|intact:EBI-1965079|uniprotkb:F8VTJ5|uniprotkb:Q59GV3	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:smrc2_human(display_long)|uniprotkb:SMARCC2(gene name)|psi-mi:SMARCC2(display_short)|uniprotkb:BAF170(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2(gene name synonym)|uniprotkb:SWI/SNF complex 170 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 170(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339253|imex:IM-11696-598	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	ensembl:ENSG00000139613(gene)|ensembl:ENST00000267064(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR038044|mint:Q8TAQ2|rcsb pdb:6KAG|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_003066.2|refseq:NP_001123892.1|refseq:NP_620706.1|refseq:NP_001317217.1|dip:DIP-27611N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:60gIB3J1YI/FzqVCzdoSg1Oj3ME9606	intact-crc:25346AF71C201B1E|rigid:/YquaIhI+KjPthKcBny6+8UJu08	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q9BRB3	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-2339260|uniprotkb:O14927|uniprotkb:A2IDE1|uniprotkb:Q96G00|uniprotkb:Q9UJH4|uniprotkb:Q96S22|uniprotkb:D3DU52|intact:EBI-28972732|ensembl:ENSP00000026218	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:pigq_human(display_long)|uniprotkb:PIGQ(gene name)|psi-mi:PIGQ(display_short)|uniprotkb:GPI1(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class Q protein(gene name synonym)|uniprotkb:N-acetylglucosamyl transferase component GPI1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339259|imex:IM-11696-600	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	ensembl:ENSP00000026218|ensembl:ENST00000321878|ensembl:ENSP00000326674|ensembl:ENST00000409527|ensembl:ENSP00000386760|ensembl:ENST00000470411|ensembl:ENSP00000439650|refseq:NP_004195.2|refseq:NP_683721.1|ensembl:ENSG00000007541(gene)|ensembl:ENST00000026218(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|interpro:IPR007720(N-acetylglucosaminyl transferase component)|reactome:R-HSA-162710	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:nL4mUBYkxZwFJqjKwdm7qAZU8NI9606	intact-crc:8215ED5FCB83018D|rigid:hby0GWJQKKh9P+3o8KJaNCZ/Hw8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q9BRG2	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-2339271|uniprotkb:Q9Y2X4|uniprotkb:B4DRS7|uniprotkb:A8K9R6|intact:EBI-28982569|ensembl:ENSP00000245908	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:sh23a_human(display_long)|uniprotkb:SH2D3A(gene name)|psi-mi:SH2D3A(display_short)|uniprotkb:NSP1(gene name synonym)|uniprotkb:Novel SH2-containing protein 1(gene name synonym)|uniprotkb:UNQ175/PRO201(orf name)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339276|imex:IM-11696-601	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_005481.2|refseq:XP_005259529.1|ensembl:ENSP00000245908|ensembl:ENST00000437152|ensembl:ENSP00000393303|ensembl:ENSG00000125731(gene)|ensembl:ENST00000245908(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|interpro:IPR000980(SH2 motif)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR023578|interpro:IPR036860|interpro:IPR036964|interpro:IPR044102|mint:Q9BRG2	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:8PTqqhIlumS0fnzVS9vJAZPByQQ9606	intact-crc:B72514FAFB0B0E67|rigid:5Mt5tNtiZkNZy4h4cKF0s60mEzc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NP58	uniprotkb:Q99816	intact:EBI-2115230|uniprotkb:O75542|uniprotkb:Q49A66|uniprotkb:Q59GQ5|uniprotkb:Q6ZME6|uniprotkb:Q96ME8|uniprotkb:Q9HAQ6|uniprotkb:Q9HAQ7|ensembl:ENSP00000265316	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	psi-mi:abcb6_human(display_long)|uniprotkb:ABCB6(gene name)|psi-mi:ABCB6(display_short)|uniprotkb:MTABC3(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:UMAT(gene name synonym)|uniprotkb:Mitochondrial ABC transporter 3(gene name synonym)|uniprotkb:Ubiquitously-expressed mammalian ABC half transporter(gene name synonym)|uniprotkb:P-glycoprotein-related protein(gene name synonym)|uniprotkb:ABC-type heme transporter ABCB6(gene name synonym)	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339279|imex:IM-11696-602	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005680.1|interpro:IPR027417|interpro:IPR032410|interpro:IPR036640|interpro:IPR039421|mint:Q9NP58|rcsb pdb:3NH6|rcsb pdb:3NH9|rcsb pdb:3NHA|rcsb pdb:3NHB|rcsb pdb:7D7N|rcsb pdb:7D7R|reactome:R-HSA-1369007|reactome:R-HSA-5683371|ensembl:ENSG00000115657(gene)|ensembl:ENST00000265316(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006778"(porphyrin-containing compound metabolic process)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007420"(brain development)|go:"GO:0015439"(ABC-type heme transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015886"(heme transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033013"(tetrapyrrole metabolic process)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035351"(heme transmembrane transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042168"(heme metabolic process)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|go:"GO:0043588"(skin development)|go:"GO:0046906"(tetrapyrrole binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098849"(cellular detoxification of cadmium ion)|go:"GO:0140359"(ABC-type transporter activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903232"(melanosome assembly)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:3Zyw4d16oU1oT0eiAcOds3s1ZVQ9606	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	intact-crc:3307EC1E89C8EDC2|rigid:ELsl/oivO9Tmk6Hf9M5iMmeZPP4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q13561	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-715074|uniprotkb:Q86YN2|uniprotkb:Q9BW17|uniprotkb:B2RBK5|ensembl:ENSP00000447824	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:dctn2_human(display_long)|uniprotkb:Dynactin complex 50 kDa subunit(gene name synonym)|uniprotkb:50 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:p50 dynamitin(gene name synonym)|uniprotkb:DCTN2(gene name)|psi-mi:DCTN2(display_short)|uniprotkb:DCTN50(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339282|imex:IM-11696-603	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_006391.1|refseq:NP_001248341.1|refseq:NP_001248342.1|dip:DIP-37545N|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|ensembl:ENSG00000175203(gene)|ensembl:ENST00000548249(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030286"(dynein complex)|go:"GO:0030426"(growth cone)|go:"GO:0030507"(spectrin binding)|go:"GO:0031982"(vesicle)|go:"GO:0032402"(melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071539"(protein localization to centrosome)|interpro:IPR028133|mint:Q13561|reactome:R-HSA-2132295	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:JrL5jUtArek+zqmCkPKomnjuSf09606	intact-crc:E8992D173EC8E2FB|rigid:pXuPTkP1FrjKa2z5qg13lheK8Ac	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16891	uniprotkb:Q99816	intact:EBI-473801|uniprotkb:Q68D41|uniprotkb:B2R5N6|uniprotkb:Q14539|uniprotkb:Q15092|uniprotkb:Q69HW5|uniprotkb:Q6IBL0|uniprotkb:Q7Z3X1|uniprotkb:Q8TAJ5|uniprotkb:Q9P0V2|uniprotkb:B1H0U5|ensembl:ENSP00000387262	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	psi-mi:mic60_human(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:p87/89(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 4/52 protein(gene name synonym)|uniprotkb:MIC60(gene name synonym)|uniprotkb:IMMT(gene name)|psi-mi:IMMT(display_short)|uniprotkb:HMP(gene name synonym)|uniprotkb:MINOS2(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)|uniprotkb:PIG4(orf name)|uniprotkb:PIG52(orf name)	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339288|imex:IM-11696-605	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001093639.1|refseq:NP_001093640.1|refseq:NP_006830.2|refseq:XP_005264170.1|ensembl:ENSG00000132305(gene)|ensembl:ENST00000410111(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016020"(membrane)|go:"GO:0042407"(cristae formation)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|interpro:IPR019133|mint:Q16891|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex)|refseq:XP_016858683.1|dip:DIP-32517N	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:WypdAh4p5IjofFakBmSBwTIWWEs9606	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	intact-crc:973DD32BB5105423|rigid:hcQpTH7S1eUwRrFhp8wPiWKqVhA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q7L5N1	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-486838|uniprotkb:O15387|uniprotkb:A4D2A3|ensembl:ENSP00000304102	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:csn6_human(display_long)|uniprotkb:COPS6(gene name)|psi-mi:COPS6(display_short)|uniprotkb:CSN6(gene name synonym)|uniprotkb:HVIP(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 6(gene name synonym)|uniprotkb:Vpr-interacting protein(gene name synonym)|uniprotkb:MOV34 homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339285|imex:IM-11696-604	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_006824.2|ensembl:ENSG00000168090(gene)|ensembl:ENST00000303904(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR033859|interpro:IPR024969|interpro:IPR037518|mint:Q7L5N1|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4QFT|rcsb pdb:4R14|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|dip:DIP-32655N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:hyuYyAujJCJtbfS2tJ+UgH7jWP89606	intact-crc:96B984FD77D5A95E|rigid:0CzBetkFf1bIHprpR/rQoLNHmoM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:O14579	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-711301|uniprotkb:O76097|ensembl:ENSP00000262812|uniprotkb:Q9UGP6|uniprotkb:Q6IBB8|uniprotkb:A6NKA3|uniprotkb:A6NE29	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:cope_human(display_long)|uniprotkb:COPE(gene name)|psi-mi:COPE(display_short)|uniprotkb:Epsilon-coat protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339298|imex:IM-11696-607	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_009194.2|ensembl:ENSG00000105669(gene)|ensembl:ENST00000262812(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0099612"(protein localization to axon)|interpro:IPR006822(Coatomer, epsilon subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:O14579|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_955474.1|refseq:NP_955476.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:gjrR0x7iNHl/nEDtoZTjThB1dgs9606	intact-crc:2C0A275B26293B1E|rigid:4v73zjDB7Qe5Uh7U7W3v/JzD0P8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q9BUJ2	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-1018153|uniprotkb:O76022|uniprotkb:Q6ZSZ0|uniprotkb:Q7L8P4|uniprotkb:Q8N6Z4|uniprotkb:Q96G37|uniprotkb:Q9HAL3|uniprotkb:Q9UG75|intact:EBI-3183399|intact:EBI-2339292|uniprotkb:B3KMW7|ensembl:ENSP00000375863|intact:EBI-2563529	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:hnrl1_human(display_long)|uniprotkb:E1BAP5(gene name synonym)|uniprotkb:HNRNPUL1(gene name)|psi-mi:HNRNPUL1(display_short)|uniprotkb:HNRPUL1(gene name synonym)|uniprotkb:Adenovirus early region 1B-associated protein 5(gene name synonym)|uniprotkb:E1B-55 kDa-associated protein 5(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339291|imex:IM-11696-606	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_008971.2|refseq:NP_653333.1|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027025|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q9BUJ2|reactome:R-HSA-72163|ensembl:ENSG00000105323(gene)|ensembl:ENST00000392006(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|refseq:NP_001308140.1|refseq:NP_001308137.1|dip:DIP-39419N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:IahA7SVR1NmvldrWKQlAwApinQE9606	intact-crc:98AA8BCFD57D5457|rigid:CCtMVwy5ZAjZtF6X5j6AzhFqVNw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q14160	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339301|imex:IM-11696-608	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	intact-crc:5535DE5E19448F1D|rigid:9LDMinWzuJQkIr7ETcrsqvHF54M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKU7	uniprotkb:Q99816	intact:EBI-2339304|uniprotkb:Q9BUS8|uniprotkb:B7Z5W4|uniprotkb:Q6ZWP6|ensembl:ENSP00000281182	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	psi-mi:acad8_human(display_long)|uniprotkb:ACAD8(gene name)|psi-mi:ACAD8(display_short)|uniprotkb:ARC42(gene name synonym)|uniprotkb:IBD(gene name synonym)|uniprotkb:Acyl-CoA dehydrogenase family member 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 42 kDa component(gene name synonym)	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339309|imex:IM-11696-609	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055199.1|ensembl:ENSG00000151498(gene)|ensembl:ENST00000281182(transcript)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006574"(valine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034178|interpro:IPR036250|interpro:IPR037069|rcsb pdb:1RX0|reactome:R-HSA-70895	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:66N8jQRgNFF3JmPdF2yXteflH7k9606	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	intact-crc:A1AA63C9DCDBA828|rigid:OQTI4gli2Fpv1tqv6Xe7Go8kDqc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28838	uniprotkb:Q99816	intact:EBI-2339312|uniprotkb:Q6IAM6|uniprotkb:Q6P0L6|uniprotkb:Q9UQE3|uniprotkb:B3KMQ3|ensembl:ENSP00000226299|ensembl:ENSP00000481000	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	psi-mi:ampl_human(display_long)|uniprotkb:LAP3(gene name)|psi-mi:LAP3(display_short)|uniprotkb:LAPEP(gene name synonym)|uniprotkb:PEPS(gene name synonym)|uniprotkb:Leucyl aminopeptidase(gene name synonym)|uniprotkb:Leucine aminopeptidase 3(gene name synonym)|uniprotkb:Proline aminopeptidase(gene name synonym)|uniprotkb:Prolyl aminopeptidase(gene name synonym)|uniprotkb:Peptidase S(gene name synonym)|uniprotkb:Cysteinylglycine-S-conjugate dipeptidase(gene name synonym)	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339319|imex:IM-11696-610	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056991.2|ensembl:ENSG00000002549(gene)|ensembl:ENST00000226299(transcript)|ensembl:ENST00000618908(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030496"(midbody)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000819(Peptidase M17, leucyl aminopeptidase, C-terminal)|interpro:IPR008283(Peptidase M17, leucyl aminopeptidase, N-terminal)|interpro:IPR011356(Peptidase M17, leucyl aminopeptidase)|interpro:IPR023042|interpro:IPR043472|mint:P28838	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:BGEwM09Jm/Nn1CwI+QguAqIwGzw9606	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	intact-crc:FE1BCDA92186B436|rigid:WxwWROwB5LjQ5//xMfNd81XLmUo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q8IV63	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-1058605|uniprotkb:Q502Y2|uniprotkb:Q9P2V8|uniprotkb:A8KA53|intact:EBI-1795523|uniprotkb:A6NEG5|ensembl:ENSP00000324636|ensembl:ENSP00000469880|ensembl:ENSP00000473171	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:vrk3_human(display_long)|uniprotkb:VRK3(gene name)|psi-mi:VRK3(display_short)|uniprotkb:Vaccinia-related kinase 3(gene name synonym)|uniprotkb:Serine/threonine-protein pseudokinase VRK3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339325|imex:IM-11696-612	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_001295349.1|refseq:NP_057524.3|refseq:NP_001020949.1|ensembl:ENSG00000105053(gene)|ensembl:ENST00000316763(transcript)|ensembl:ENST00000594948(transcript)|ensembl:ENST00000599538(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR026870|rcsb pdb:2JII|reactome:R-HSA-202670|refseq:XP_005259028.1|refseq:XP_005259029.1|refseq:XP_006723300.1|refseq:XP_006723301.1|refseq:XP_011525325.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:eoBtIgSkVcOE5bw/By6UEqbiO/I9606	intact-crc:6D3D798DA4D676ED|rigid:ZJHmTPk8R/kaG2ukWmaMfId0BEU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q9P0J0	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339322|imex:IM-11696-611	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606	intact-crc:441C5DA86EC045E3|rigid:4+wkkuE5FlcN79H4UARn0BHa7TA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:H0Y7E6	uniprotkb:Q99816	intact:EBI-2339329|ensembl:ENSP00000412349	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	psi-mi:h0y7e6_human(display_long)|uniprotkb:EIF3L(gene name)|psi-mi:EIF3L(display_short)	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339328|imex:IM-11696-613	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:B0QY85(uniprot-removed-ac)|ensembl:ENSG00000100129(gene)|ensembl:ENST00000450376(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|interpro:IPR019382	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:SzBi3iv/QX7U858AUvOw7IJ5ALs9606	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	intact-crc:7C4A3FB839951C8D|rigid:99kbF4qQuh60a74FyDVO2LQmDvY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q53EZ4	uniprotkb:Q99816	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339338|imex:IM-11696-615	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	intact-crc:2C1717C772B927FC|rigid:MqhkUeXdHGK0v3vLhhAkkO1oEh4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IXH7	uniprotkb:Q99816	intact:EBI-536725|uniprotkb:Q9BYL2|uniprotkb:Q9H405|uniprotkb:Q9H888|uniprotkb:Q9H8T3|uniprotkb:Q9NVX5|uniprotkb:Q9P029|uniprotkb:Q9UGN1|uniprotkb:Q9UGN2|uniprotkb:Q9UGN3|uniprotkb:B4DE06	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	psi-mi:nelfd_human(display_long)|uniprotkb:NELFCD(gene name)|psi-mi:NELFCD(display_short)|uniprotkb:NELFD(gene name synonym)|uniprotkb:TH1(gene name synonym)|uniprotkb:TH1-like protein(gene name synonym)|uniprotkb:TH1L(gene name synonym)|uniprotkb:HSPC130(orf name)	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339335|imex:IM-11696-614	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR006942(TH1 protein)|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_945327.2|mint:Q8IXH7|dip:DIP-34061N	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5x+m/j9x6zagup2Ptb1uFoNtDUE9606	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	intact-crc:12010B6FD1BBC164|rigid:pgHNMFBdAxEskgt9TKYpw8o7Qwo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q9H857	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-359244|uniprotkb:O95888|uniprotkb:Q96C80|uniprotkb:Q9H9Z8|uniprotkb:C9JTZ6|uniprotkb:E9PAL9|intact:EBI-11044897|ensembl:ENSP00000302468	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:nt5d2_human(display_long)|uniprotkb:NT5DC2(gene name)|psi-mi:NT5DC2(display_short)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339341|imex:IM-11696-616	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_001127703.1|refseq:NP_075059.1|refseq:XP_005265463.1|refseq:XP_006713368.1|ensembl:ENSG00000168268(gene)|ensembl:ENST00000307076(transcript)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:nfT/9N1bWVadX70eY1G0GS9pS9U9606	intact-crc:7E3EBE11ABEA6D67|rigid:XO870Y4O/BlC82THA7ticam4i8I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6I9Y2	uniprotkb:Q99816	intact:EBI-716286|uniprotkb:Q6P1L3|uniprotkb:Q8WUF2|uniprotkb:Q9H5H0|ensembl:ENSP00000295899	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	psi-mi:thoc7_human(display_long)|uniprotkb:Functional spliceosome-associated protein 24(gene name synonym)|uniprotkb:hTREX30(gene name synonym)|uniprotkb:NIF3L1BP1(gene name synonym)|uniprotkb:Ngg1-interacting factor 3-like protein 1-binding protein 1(gene name synonym)|uniprotkb:THOC7(gene name)|psi-mi:THOC7(display_short)	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339344|imex:IM-11696-617	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001272333.1|refseq:NP_079351.2|ensembl:ENSG00000163634(gene)|ensembl:ENST00000295899(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|interpro:IPR008501(Protein of unknown function DUF783)|mint:Q6I9Y2|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:15M7nouxNuzlKZPawajrahz0LAY9606	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	intact-crc:B4DCBCE9FCCA03C7|rigid:6pqXiVYnZPh+w1OmaqkJcv3sWHc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49459	uniprotkb:P35613	intact:EBI-2339348|uniprotkb:A6NMF5|uniprotkb:Q96FX4|uniprotkb:B2R7R9|uniprotkb:Q4TTG1|uniprotkb:D3DWI1|uniprotkb:A6NFE9|uniprotkb:A6NGR2|ensembl:ENSP00000360613	intact:EBI-750709|uniprotkb:Q7Z796|uniprotkb:Q8IZL7|intact:EBI-2553051|uniprotkb:A6NJW1|uniprotkb:D3YLG5|ensembl:ENSP00000333769	psi-mi:ube2a_human(display_long)|uniprotkb:UBE2A(gene name)|psi-mi:UBE2A(display_short)|uniprotkb:RAD6A(gene name synonym)|uniprotkb:Ubiquitin-protein ligase A(gene name synonym)|uniprotkb:Ubiquitin carrier protein A(gene name synonym)|uniprotkb:RAD6 homolog A(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme A(gene name synonym)	psi-mi:basi_human(display_long)|uniprotkb:Leukocyte activation antigen M6(gene name synonym)|uniprotkb:Collagenase stimulatory factor(gene name synonym)|uniprotkb:Extracellular matrix metalloproteinase inducer(gene name synonym)|uniprotkb:5F7(gene name synonym)|uniprotkb:Tumor cell-derived collagenase stimulatory factor(gene name synonym)|uniprotkb:OK blood group antigen(gene name synonym)|uniprotkb:BSG(gene name)|psi-mi:BSG(display_short)|uniprotkb:UNQ6505/PRO21383(orf name)|uniprotkb:Hepatoma-associated antigen(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339347|imex:IM-11696-618	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003327.2|refseq:NP_861427.1|refseq:NP_001269090.1|dip:DIP-24260N|ensembl:ENSG00000077721(gene)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033503"(HULC complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P49459|rcsb pdb:6CYO|rcsb pdb:6CYR|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|ensembl:ENST00000371558(transcript)	refseq:NP_001719.2|refseq:NP_940991.1|refseq:NP_940993.1|refseq:NP_001309172.1|refseq:NP_940992.1|refseq:XP_016882662.1|dip:DIP-50310N|ensembl:ENSG00000172270(gene)|ensembl:ENST00000333511(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0003407"(neural retina development)|go:"GO:0005537"(mannose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007566"(embryo implantation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046689"(response to mercury ion)|go:"GO:0046697"(decidualization)|go:"GO:0051591"(response to cAMP)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904466"(positive regulation of matrix metallopeptidase secretion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043204|interpro:IPR044157|mint:P35613|rcsb pdb:3B5H|rcsb pdb:3I84|rcsb pdb:3I85|rcsb pdb:3QQN|rcsb pdb:4U0Q|rcsb pdb:5X0T|rcsb pdb:5XF0|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|reactome:R-HSA-1474228|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-70268|rcsb pdb:3QR2	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:T6Mzgy6RHO9HoEIG3FmQvsP32vU9606	rogid:jVbDR+TKBzTjXoxR4At6XQg59ZA9606	intact-crc:994ED3C97ACCD460|rigid:+uxNLn3fdGpEP+vUw4M3+Mn6EQg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49459	uniprotkb:O14929	intact:EBI-2339348|uniprotkb:A6NMF5|uniprotkb:Q96FX4|uniprotkb:B2R7R9|uniprotkb:Q4TTG1|uniprotkb:D3DWI1|uniprotkb:A6NFE9|uniprotkb:A6NGR2|ensembl:ENSP00000360613	intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108	psi-mi:ube2a_human(display_long)|uniprotkb:UBE2A(gene name)|psi-mi:UBE2A(display_short)|uniprotkb:RAD6A(gene name synonym)|uniprotkb:Ubiquitin-protein ligase A(gene name synonym)|uniprotkb:Ubiquitin carrier protein A(gene name synonym)|uniprotkb:RAD6 homolog A(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme A(gene name synonym)	psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339358|imex:IM-11696-619	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003327.2|refseq:NP_861427.1|refseq:NP_001269090.1|dip:DIP-24260N|ensembl:ENSG00000077721(gene)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033503"(HULC complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P49459|rcsb pdb:6CYO|rcsb pdb:6CYR|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|ensembl:ENST00000371558(transcript)	refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:T6Mzgy6RHO9HoEIG3FmQvsP32vU9606	rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606	intact-crc:29FA31C00D2F9EE2|rigid:S/JxW1pc6Xy91fPTeNXkcdc3c14	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVF9	uniprotkb:P49459	intact:EBI-751864|uniprotkb:B7Z7K1|uniprotkb:Q5SXX5|uniprotkb:Q68CK3|uniprotkb:Q96G05|ensembl:ENSP00000356170	intact:EBI-2339348|uniprotkb:A6NMF5|uniprotkb:Q96FX4|uniprotkb:B2R7R9|uniprotkb:Q4TTG1|uniprotkb:D3DWI1|uniprotkb:A6NFE9|uniprotkb:A6NGR2|ensembl:ENSP00000360613	psi-mi:eki2_human(display_long)|uniprotkb:ETNK2(gene name)|psi-mi:ETNK2(display_short)|uniprotkb:EKI2(gene name synonym)|uniprotkb:Ethanolamine kinase-like protein(gene name synonym)|uniprotkb:HMFT1716(orf name)	psi-mi:ube2a_human(display_long)|uniprotkb:UBE2A(gene name)|psi-mi:UBE2A(display_short)|uniprotkb:RAD6A(gene name synonym)|uniprotkb:Ubiquitin-protein ligase A(gene name synonym)|uniprotkb:Ubiquitin carrier protein A(gene name synonym)|uniprotkb:RAD6 homolog A(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme A(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339371|imex:IM-11696-621	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060678.2|refseq:NP_001284689.1|refseq:NP_001284690.1|refseq:NP_001284691.1|ensembl:ENSG00000143845(gene)|ensembl:ENST00000367202(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0004305"(ethanolamine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0035264"(multicellular organism growth)|interpro:IPR011009(Protein kinase-like)|reactome:R-HSA-1483213	refseq:NP_003327.2|refseq:NP_861427.1|refseq:NP_001269090.1|dip:DIP-24260N|ensembl:ENSG00000077721(gene)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033503"(HULC complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P49459|rcsb pdb:6CYO|rcsb pdb:6CYR|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|ensembl:ENST00000371558(transcript)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:aZ+GrsqSpVjuyjNe6KyQA6h5QEg9606	rogid:T6Mzgy6RHO9HoEIG3FmQvsP32vU9606	intact-crc:1BE936D9E90FE8E0|rigid:JpNCn2JJt/VbXhbRexjtPcxhTeM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49459	uniprotkb:Q5T4S7	intact:EBI-2339348|uniprotkb:A6NMF5|uniprotkb:Q96FX4|uniprotkb:B2R7R9|uniprotkb:Q4TTG1|uniprotkb:D3DWI1|uniprotkb:A6NFE9|uniprotkb:A6NGR2|ensembl:ENSP00000360613	intact:EBI-1995940|intact:EBI-1059327|uniprotkb:A8MPT2|uniprotkb:A8MQ33|uniprotkb:A8MQB1|uniprotkb:O60646|uniprotkb:O75050|uniprotkb:Q4QRK5|uniprotkb:Q5T4S8|uniprotkb:Q5T4S9|uniprotkb:Q5TBN8|uniprotkb:Q5TBP2|uniprotkb:Q6DKH8|uniprotkb:Q6P4A4|uniprotkb:Q7L8P7|uniprotkb:Q8IXJ4|uniprotkb:Q8TDN5|uniprotkb:Q8WV67|uniprotkb:Q9HA46|uniprotkb:Q9P2N9|uniprotkb:Q9UG82|ensembl:ENSP00000364403	psi-mi:ube2a_human(display_long)|uniprotkb:UBE2A(gene name)|psi-mi:UBE2A(display_short)|uniprotkb:RAD6A(gene name synonym)|uniprotkb:Ubiquitin-protein ligase A(gene name synonym)|uniprotkb:Ubiquitin carrier protein A(gene name synonym)|uniprotkb:RAD6 homolog A(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme A(gene name synonym)	psi-mi:ubr4_human(display_long)|uniprotkb:UBR4(gene name)|psi-mi:UBR4(display_short)|uniprotkb:KIAA0462(gene name synonym)|uniprotkb:KIAA1307(gene name synonym)|uniprotkb:RBAF600(gene name synonym)|uniprotkb:ZUBR1(gene name synonym)|uniprotkb:N-recognin-4(gene name synonym)|uniprotkb:Zinc finger UBR1-type protein 1(gene name synonym)|uniprotkb:Retinoblastoma-associated factor of 600 kDa(gene name synonym)|uniprotkb:600 kDa retinoblastoma protein-associated factor(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339368|imex:IM-11696-620	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003327.2|refseq:NP_861427.1|refseq:NP_001269090.1|dip:DIP-24260N|ensembl:ENSG00000077721(gene)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033503"(HULC complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P49459|rcsb pdb:6CYO|rcsb pdb:6CYR|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|ensembl:ENST00000371558(transcript)	refseq:NP_065816.2|ensembl:ENST00000375218|ensembl:ENSP00000364403|ensembl:ENSP00000364366|ensembl:ENSG00000127481(gene)|ensembl:ENST00000375254(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025704|interpro:IPR036322|mint:Q5T4S7|reactome:R-HSA-6798695|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:T6Mzgy6RHO9HoEIG3FmQvsP32vU9606	rogid:8Iown8oj965YAir+95+3om5+1YM9606	intact-crc:9D45B46B0922A25B|rigid:2dJCrxCbNcF7FAaQvIfUVA2tx5A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49459	uniprotkb:Q8TAZ6	intact:EBI-2339348|uniprotkb:A6NMF5|uniprotkb:Q96FX4|uniprotkb:B2R7R9|uniprotkb:Q4TTG1|uniprotkb:D3DWI1|uniprotkb:A6NFE9|uniprotkb:A6NGR2|ensembl:ENSP00000360613	intact:EBI-2339374|uniprotkb:Q8N7E5|uniprotkb:Q5I2A4|ensembl:ENSP00000268595	psi-mi:ube2a_human(display_long)|uniprotkb:UBE2A(gene name)|psi-mi:UBE2A(display_short)|uniprotkb:RAD6A(gene name synonym)|uniprotkb:Ubiquitin-protein ligase A(gene name synonym)|uniprotkb:Ubiquitin carrier protein A(gene name synonym)|uniprotkb:RAD6 homolog A(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme A(gene name synonym)	psi-mi:cklf2_human(display_long)|uniprotkb:CMTM2(gene name)|psi-mi:CMTM2(display_short)|uniprotkb:CKLFSF2(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339379|imex:IM-11696-622	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003327.2|refseq:NP_861427.1|refseq:NP_001269090.1|dip:DIP-24260N|ensembl:ENSG00000077721(gene)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033503"(HULC complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P49459|rcsb pdb:6CYO|rcsb pdb:6CYR|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|ensembl:ENST00000371558(transcript)	refseq:NP_653274.1|refseq:NP_001186246.1|ensembl:ENSG00000140932(gene)|ensembl:ENST00000268595(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006935"(chemotaxis)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008253(Marvel)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:T6Mzgy6RHO9HoEIG3FmQvsP32vU9606	rogid:Dtw7sdyb44iVQB9A8O6XP2iuzi49606	intact-crc:53F5F0E7CE9D2E4E|rigid:yr0tJGIHNaexuNM7JSxUCk1a0SM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63146	uniprotkb:Q5T4S7	intact:EBI-712629|uniprotkb:P23567|uniprotkb:Q4PJ15|ensembl:ENSP00000265339|uniprotkb:Q9D0J6|uniprotkb:B2R503|uniprotkb:D3DQA2	intact:EBI-1995940|intact:EBI-1059327|uniprotkb:A8MPT2|uniprotkb:A8MQ33|uniprotkb:A8MQB1|uniprotkb:O60646|uniprotkb:O75050|uniprotkb:Q4QRK5|uniprotkb:Q5T4S8|uniprotkb:Q5T4S9|uniprotkb:Q5TBN8|uniprotkb:Q5TBP2|uniprotkb:Q6DKH8|uniprotkb:Q6P4A4|uniprotkb:Q7L8P7|uniprotkb:Q8IXJ4|uniprotkb:Q8TDN5|uniprotkb:Q8WV67|uniprotkb:Q9HA46|uniprotkb:Q9P2N9|uniprotkb:Q9UG82|ensembl:ENSP00000364403	psi-mi:ube2b_human(display_long)|uniprotkb:Ubiquitin-protein ligase B(gene name synonym)|uniprotkb:Ubiquitin carrier protein B(gene name synonym)|uniprotkb:RAD6 homolog B(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa(gene name synonym)|uniprotkb:UBE2B(gene name)|psi-mi:UBE2B(display_short)|uniprotkb:RAD6B(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme B(gene name synonym)	psi-mi:ubr4_human(display_long)|uniprotkb:UBR4(gene name)|psi-mi:UBR4(display_short)|uniprotkb:KIAA0462(gene name synonym)|uniprotkb:KIAA1307(gene name synonym)|uniprotkb:RBAF600(gene name synonym)|uniprotkb:ZUBR1(gene name synonym)|uniprotkb:N-recognin-4(gene name synonym)|uniprotkb:Zinc finger UBR1-type protein 1(gene name synonym)|uniprotkb:Retinoblastoma-associated factor of 600 kDa(gene name synonym)|uniprotkb:600 kDa retinoblastoma protein-associated factor(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339389|imex:IM-11696-624	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000119048(gene)|ensembl:ENST00000265339(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001741"(XY body)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0009411"(response to UV)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR023313|mint:P63146|rcsb pdb:1JAS|rcsb pdb:1NXA|rcsb pdb:2Y4W|rcsb pdb:2YB6|rcsb pdb:2YBF|reactome:R-HSA-110314|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0033503"(HULC complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0050821"(protein stabilization)|go:"GO:0051026"(chiasma assembly)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070076"(histone lysine demethylation)|go:"GO:0070193"(synaptonemal complex organization)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070829"(obsolete heterochromatin maintenance)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|refseq:NP_003328.1|dip:DIP-29832N	refseq:NP_065816.2|ensembl:ENST00000375218|ensembl:ENSP00000364403|ensembl:ENSP00000364366|ensembl:ENSG00000127481(gene)|ensembl:ENST00000375254(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025704|interpro:IPR036322|mint:Q5T4S7|reactome:R-HSA-6798695|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:JvcUPH+3qQXicPsIRFnW19NOc3c9606	rogid:8Iown8oj965YAir+95+3om5+1YM9606	intact-crc:0D2A97F4321DF5B0|rigid:BDuIPilZgLa8zBtMAlRvqAB/dZ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63146	uniprotkb:Q92985	intact:EBI-712629|uniprotkb:P23567|uniprotkb:Q4PJ15|ensembl:ENSP00000265339|uniprotkb:Q9D0J6|uniprotkb:B2R503|uniprotkb:D3DQA2	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	psi-mi:ube2b_human(display_long)|uniprotkb:Ubiquitin-protein ligase B(gene name synonym)|uniprotkb:Ubiquitin carrier protein B(gene name synonym)|uniprotkb:RAD6 homolog B(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa(gene name synonym)|uniprotkb:UBE2B(gene name)|psi-mi:UBE2B(display_short)|uniprotkb:RAD6B(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme B(gene name synonym)	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339382|imex:IM-11696-623	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000119048(gene)|ensembl:ENST00000265339(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001741"(XY body)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0009411"(response to UV)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR023313|mint:P63146|rcsb pdb:1JAS|rcsb pdb:1NXA|rcsb pdb:2Y4W|rcsb pdb:2YB6|rcsb pdb:2YBF|reactome:R-HSA-110314|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0033503"(HULC complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0050821"(protein stabilization)|go:"GO:0051026"(chiasma assembly)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070076"(histone lysine demethylation)|go:"GO:0070193"(synaptonemal complex organization)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070829"(obsolete heterochromatin maintenance)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|refseq:NP_003328.1|dip:DIP-29832N	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:JvcUPH+3qQXicPsIRFnW19NOc3c9606	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	intact-crc:A9AC77DCAAA7432A|rigid:qCMbbedQMeBgVbjO+ZYo5Qe0DDk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63146	uniprotkb:Q9NS91	intact:EBI-712629|uniprotkb:P23567|uniprotkb:Q4PJ15|ensembl:ENSP00000265339|uniprotkb:Q9D0J6|uniprotkb:B2R503|uniprotkb:D3DQA2	intact:EBI-2339393|uniprotkb:Q9NRT6|uniprotkb:Q58F55|ensembl:ENSP00000264926	psi-mi:ube2b_human(display_long)|uniprotkb:Ubiquitin-protein ligase B(gene name synonym)|uniprotkb:Ubiquitin carrier protein B(gene name synonym)|uniprotkb:RAD6 homolog B(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa(gene name synonym)|uniprotkb:UBE2B(gene name)|psi-mi:UBE2B(display_short)|uniprotkb:RAD6B(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme B(gene name synonym)	psi-mi:rad18_human(display_long)|uniprotkb:RAD18(gene name)|psi-mi:RAD18(display_short)|uniprotkb:RNF73(gene name synonym)|uniprotkb:Postreplication repair protein RAD18(gene name synonym)|uniprotkb:RING finger protein 73(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RAD18(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339392|imex:IM-11696-625	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000119048(gene)|ensembl:ENST00000265339(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001741"(XY body)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0009411"(response to UV)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR023313|mint:P63146|rcsb pdb:1JAS|rcsb pdb:1NXA|rcsb pdb:2Y4W|rcsb pdb:2YB6|rcsb pdb:2YBF|reactome:R-HSA-110314|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0033503"(HULC complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0050821"(protein stabilization)|go:"GO:0051026"(chiasma assembly)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070076"(histone lysine demethylation)|go:"GO:0070193"(synaptonemal complex organization)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070829"(obsolete heterochromatin maintenance)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|refseq:NP_003328.1|dip:DIP-29832N	refseq:NP_064550.3|ensembl:ENSP00000264926|dip:DIP-29831N|ensembl:ENSG00000070950(gene)|ensembl:ENST00000264926(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097505"(Rad6-Rad18 complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036361|interpro:IPR039577|mint:Q9NS91|rcsb pdb:2MRE|rcsb pdb:2MRF|rcsb pdb:2Y43|rcsb pdb:2YBF|rcsb pdb:5VF0|reactome:R-HSA-110314|reactome:R-HSA-8866654|go:"GO:0060548"(negative regulation of cell death)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:JvcUPH+3qQXicPsIRFnW19NOc3c9606	rogid:/HmKCLqG1BxzmIWCgVpOw/gzJc49606	intact-crc:D59F207D804618E5|rigid:JneWliiSgYIVdf1EuPV9Qcwujbo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P78545	uniprotkb:P51668	intact:EBI-1057285|uniprotkb:Q7Z3X2|uniprotkb:Q8NFG2|uniprotkb:Q99718|uniprotkb:Q6IAP8|uniprotkb:Q7RU03|uniprotkb:B2R5Q6|ensembl:ENSP00000352673|ensembl:ENSP00000356252|ensembl:ENSP00000356253	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:elf3_human(display_long)|uniprotkb:ELF3(gene name)|psi-mi:ELF3(display_short)|uniprotkb:ERT(gene name synonym)|uniprotkb:ESX(gene name synonym)|uniprotkb:JEN(gene name synonym)|uniprotkb:E74-like factor 3(gene name synonym)|uniprotkb:Epithelium-specific Ets transcription factor 1(gene name synonym)|uniprotkb:Epithelium-restricted Ets protein ESX(gene name synonym)|uniprotkb:Epithelial-restricted with serine box(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339401|imex:IM-11696-626	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001107781.1|refseq:NP_004424.3|ensembl:ENSG00000163435(gene)|ensembl:ENST00000359651(transcript)|ensembl:ENST00000367283(transcript)|ensembl:ENST00000367284(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001824"(blastocyst development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060056"(mammary gland involution)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR033074|interpro:IPR036388|interpro:IPR036390|interpro:IPR042693|rcsb pdb:2E8P|reactome:R-HSA-1912408	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:UR/FgxMk+J5InoP/6OCJTyCwM/s9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:6DCB627D4C122FEC|rigid:wL5YjArZcZiUcKFm4oZQIAM5AlM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q99942	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339404|imex:IM-11696-627	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606	intact-crc:F37DA955067DDB03|rigid:W7aaS1hnk5Hne0awqmX0QWngC9w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:P46779	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-366357|uniprotkb:Q6IAY0|uniprotkb:Q96FX1|uniprotkb:Q9BWQ0|uniprotkb:B2R4A6|uniprotkb:B4DEP9|uniprotkb:E9PB24|uniprotkb:C9JB50|uniprotkb:G5E9L2|ensembl:ENSP00000342787|ensembl:ENSP00000453319	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:rl28_human(display_long)|uniprotkb:RPL28(gene name)|psi-mi:RPL28(display_short)|uniprotkb:Large ribosomal subunit protein eL28(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339407|imex:IM-11696-628	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_001129608.1|refseq:NP_001129609.1|refseq:NP_000982.2|refseq:NP_001129606.1|refseq:NP_001129607.1|ensembl:ENSG00000108107(gene)|ensembl:ENST00000344063(transcript)|ensembl:ENST00000559463(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002672(Ribosomal protein L28e)|interpro:IPR029004|mint:P46779|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:I7Me1zjfxk98g6C2NoYOWlmrYVc9606	intact-crc:34226E42955B06C8|rigid:mkLLpGFAnOCJwkyMgBQDYtkPlrE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:P62081	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-354360|uniprotkb:Q6IPH1|uniprotkb:P23821|uniprotkb:P24818|uniprotkb:Q57Z92|ensembl:ENSP00000385018|ensembl:ENSP00000385286|ensembl:ENSP00000495273|ensembl:ENSP00000496654|ensembl:ENSP00000496757	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:rs7_human(display_long)|uniprotkb:RPS7(gene name)|psi-mi:RPS7(display_short)|uniprotkb:Small ribosomal subunit protein eS7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339410|imex:IM-11696-629	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_001002.1|ensembl:ENSG00000171863(gene)|ensembl:ENST00000403564(transcript)|ensembl:ENST00000406376(transcript)|ensembl:ENST00000462576(transcript)|ensembl:ENST00000645674(transcript)|ensembl:ENST00000646909(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000554(Ribosomal protein S7e)|mint:P62081|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6G4S	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:l4aG6I34lmzYhNapbdv2CAAwRwg9606	intact-crc:C6D26A078E83CE88|rigid:uXxpUbgYIhiVO18Om5ijDtb854g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q86Y13	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339422|imex:IM-11696-631	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:9D0C60A188EE2953|rigid:FZKFQG367D3xzzo9gFQRbTZAnSM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14681	uniprotkb:P51668	intact:EBI-2339413|uniprotkb:Q9BUQ1|uniprotkb:A8K7D6|uniprotkb:B4DKL6|ensembl:ENSP00000278903|ensembl:ENSP00000484510	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:ei24_human(display_long)|uniprotkb:EI24(gene name)|psi-mi:EI24(display_short)|uniprotkb:PIG8(gene name synonym)|uniprotkb:p53-induced gene 8 protein(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339419|imex:IM-11696-630	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011541371.1|refseq:NP_001277064.1|refseq:NP_004870.3|ensembl:ENSG00000149547(gene)|ensembl:ENST00000278903(transcript)|ensembl:ENST00000620753(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061676"(importin-alpha family protein binding)|interpro:IPR009890(Etoposide-induced 2.4)|mint:O14681	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:mb5BoJ3ithOKYe8mN+ZRB4UoltI9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:5A6D7817E613AD32|rigid:Hh/rLWz7XLyAHwQf6eODz5OlBgQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q8N5U6	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-714023|uniprotkb:Q92550|uniprotkb:Q9NPP8|uniprotkb:Q9ULW4|ensembl:ENSP00000322242	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:rnf10_human(display_long)|uniprotkb:RNF10(gene name)|psi-mi:RNF10(display_short)|uniprotkb:KIAA0262(gene name synonym)|uniprotkb:RIE2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339425|imex:IM-11696-632	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_055683.3|refseq:NP_001317403.1|ensembl:ENSG00000022840(gene)|ensembl:ENST00000325954(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039739|mint:Q8N5U6	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:Bca0Ae456x1eCsdlduoCbn7coUQ9606	intact-crc:3CAE062FE1A50FA4|rigid:6zZqkRcqLPKYe4omOrsJ95F/i38	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y3C5	uniprotkb:P51668	intact:EBI-396669|intact:EBI-2129167|uniprotkb:A8KAI2|uniprotkb:Q5T7R8|ensembl:ENSP00000242719	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:rnf11_human(display_long)|uniprotkb:CGI-123(orf name)|uniprotkb:RNF11(gene name)|psi-mi:RNF11(display_short)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339428|imex:IM-11696-633	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055187.1|ensembl:ENSP00000242719|ensembl:ENSG00000123091(gene)|ensembl:ENST00000242719(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042981|mint:Q9Y3C5	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Uj0YAf/t+AdYbMd6fgQ8hVKoP0w9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:F7470095319E0A58|rigid:8KJCHvUBv0bUNe/fIMo7U/wdU/4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q9NZS9	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-2130199|uniprotkb:A8K4Z9|uniprotkb:D3DUG8|uniprotkb:B4DUT0|ensembl:ENSP00000261658|ensembl:ENSP00000478190	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:bfar_human(display_long)|uniprotkb:BFAR(gene name)|psi-mi:BFAR(display_short)|uniprotkb:BAR(gene name synonym)|uniprotkb:RNF47(gene name synonym)|uniprotkb:RING finger protein 47(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339431|imex:IM-11696-634	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_057645.1|refseq:XP_005255407.1|ensembl:ENSG00000103429(gene)|ensembl:ENSG00000275618(gene)|ensembl:ENST00000261658(transcript)|ensembl:ENST00000619034(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017907	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:XDPFsRmdbch1NXffLOcE0lVrtRo9606	intact-crc:314FA571926C4F5E|rigid:6mLQ7z8wIj2v1zczZVcdnHOxZiw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q8TDN6	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-1052326|uniprotkb:Q3ZTT4|uniprotkb:Q8N453|uniprotkb:Q96DH1|uniprotkb:A8K0P5|ensembl:ENSP00000338862	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:brx1_human(display_long)|uniprotkb:BRIX1(gene name)|psi-mi:BRIX1(display_short)|uniprotkb:BXDC2(gene name synonym)|uniprotkb:BRIX(gene name synonym)|uniprotkb:Brix domain-containing protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339434|imex:IM-11696-635	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_060791.3|ensembl:ENSG00000113460(gene)|ensembl:ENST00000336767(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|interpro:IPR007109(Brix)|interpro:IPR026532|mint:Q8TDN6	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:Xa2UDOXgdmWyJ7qBZsdInDt9Vaw9606	intact-crc:95B94D45570A6F31|rigid:4t/up4rkS1GOdivCpZSHydoN5w8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BV68	uniprotkb:P51668	intact:EBI-357322|ensembl:ENSP00000292363|uniprotkb:Q9NWX1|intact:EBI-11064977	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:rn126_human(display_long)|uniprotkb:RNF126(gene name)|psi-mi:RNF126(display_short)|uniprotkb:RING finger protein 126(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339440|imex:IM-11696-637	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000070423(gene)|ensembl:ENST00000292363(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR039525|interpro:IPR039571|interpro:IPR039572|rcsb pdb:2N9O|rcsb pdb:2N9P|reactome:R-HSA-983168|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|refseq:NP_919442.1	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2019/01/23	rogid:4Z4AJGHJgoIUp9zhtfWcFBF1Fxw9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:1F3C457B92A1EB6C|rigid:ef4eBaijjMttLFIQgQuuTaDJLj0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96FW1	uniprotkb:P51668	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339437|imex:IM-11696-636	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:7F6CB417787C39D2|rigid:Z2a838aj6hzTGIXuHPSDWPM8kF4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q9Y508	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-723587|uniprotkb:Q6N0B0|uniprotkb:B2RDQ9|uniprotkb:B4DWY5|uniprotkb:E1P627|ensembl:ENSP00000244061	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:rn114_human(display_long)|uniprotkb:Zinc finger protein 313(gene name synonym)|uniprotkb:RNF114(gene name)|psi-mi:RNF114(display_short)|uniprotkb:ZNF313(gene name synonym)|uniprotkb:ZNF228(gene name synonym)|uniprotkb:Zinc finger protein 228(gene name synonym)|uniprotkb:RING finger protein 114(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF114(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339446|imex:IM-11696-639	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_061153.1|ensembl:ENSG00000124226(gene)|ensembl:ENST00000244061(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR034734|interpro:IPR042716|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:R1fX8xaGuIhy/M6cLzPeyfJBf649606	intact-crc:832C8978F83CD4CB|rigid:PI4P7dkol/4k30yef99KGIKfeN8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EP1	uniprotkb:P51668	intact:EBI-718923|uniprotkb:A6NEN5|uniprotkb:Q96SL3|uniprotkb:Q9NRT4|uniprotkb:Q9NT32|uniprotkb:Q9NVD5|uniprotkb:B4DZ77|uniprotkb:B4E2L6|ensembl:ENSP00000392395	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:chfr_human(display_long)|uniprotkb:Checkpoint with forkhead and RING finger domains protein(gene name synonym)|uniprotkb:RING finger protein 196(gene name synonym)|uniprotkb:CHFR(gene name)|psi-mi:CHFR(display_short)|uniprotkb:RNF196(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHFR(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339443|imex:IM-11696-638	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154816.1|refseq:NP_001154817.1|refseq:NP_001154818.1|refseq:NP_001154819.1|refseq:NP_060693.2|ensembl:ENSG00000072609(gene)|ensembl:ENST00000432561(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR019406|interpro:IPR040909|rcsb pdb:1LGP|rcsb pdb:1LGQ|rcsb pdb:2XOC|rcsb pdb:2XOY|rcsb pdb:2XOZ|rcsb pdb:2XP0|dip:DIP-40098N	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid://FU72n6rmuPAu+Fjm377S4nEjw9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:F0202774E4EE0A9B|rigid:Zku70D/gHILRaIFuIGF0M6dm99c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q9P2E3	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-308745|uniprotkb:Q9BQM7|uniprotkb:Q9BQM8|uniprotkb:Q9H8C1|uniprotkb:Q9H9S2|uniprotkb:Q9NUM1|uniprotkb:Q9NWW1|ensembl:ENSP00000360817|ensembl:ENSP00000379412	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:znfx1_human(display_long)|uniprotkb:ZNFX1(gene name)|psi-mi:ZNFX1(display_short)|uniprotkb:KIAA1404(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339449|imex:IM-11696-640	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_066363.1|ensembl:ENSG00000124201(gene)|ensembl:ENST00000371752(transcript)|ensembl:ENST00000396105(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0031380"(nuclear RNA-directed RNA polymerase complex)|interpro:IPR000967(Zinc finger, NF-X1-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|mint:Q9P2E3|refseq:XP_006723899.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:2vNUbYE3//YGh0eabKbzldLESF49606	intact-crc:F00CFC1CAD73FC17|rigid:bIP84t7AeL0tkCrZk6tZ3vOo6jY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q9BY78	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-2129375|uniprotkb:Q542Y8|intact:EBI-2339452|intact:EBI-28972797|ensembl:ENSP00000312439	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:rnf26_human(display_long)|uniprotkb:RNF26(gene name)|psi-mi:RNF26(display_short)|uniprotkb:RING finger protein 26(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339456|imex:IM-11696-641	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	ensembl:ENSP00000312439|refseq:NP_114404.1|ensembl:ENSG00000173456(gene)|ensembl:ENST00000311413(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007032"(endosome organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040089	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:R0awMKLLQSLU9zjVe/ivOWeYjnE9606	intact-crc:7D0335263DD1C409|rigid:ewLPbsu9n2q0BXHZxqwO6gmEp1A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q8ND25	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339459|imex:IM-11696-642	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	intact-crc:FAB206454D28076F|rigid:PJ3OdNj18WEVNReY3L2/OaMKAkw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:P08708	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-358255|uniprotkb:B2R4U4|intact:EBI-8012092|intact:EBI-11603362|intact:MINT-8395037|uniprotkb:P0CW22|ensembl:ENSP00000483755|ensembl:ENSP00000498019	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:rs17_human(display_long)|uniprotkb:RPS17(gene name)|psi-mi:RPS17(display_short)|uniprotkb:Small ribosomal subunit protein eS17(gene name synonym)|uniprotkb:RPS17L(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339462|imex:IM-11696-643	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_001012.1|ensembl:ENSG00000182774(gene)|ensembl:ENSG00000278229(gene)|ensembl:ENST00000617731(transcript)|ensembl:ENST00000647841(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR001210(Ribosomal protein S17e)|interpro:IPR018273|interpro:IPR036401|mint:P08708|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|go:"GO:0034101"(erythrocyte homeostasis)|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBS|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:st+xQCXdSObiy6cJD1cSx869V289606	intact-crc:DD0477B82384C299|rigid:gvno/7NMIiIAZZhzAs84hpzJhz4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:P78545	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-1057285|uniprotkb:Q7Z3X2|uniprotkb:Q8NFG2|uniprotkb:Q99718|uniprotkb:Q6IAP8|uniprotkb:Q7RU03|uniprotkb:B2R5Q6|ensembl:ENSP00000352673|ensembl:ENSP00000356252|ensembl:ENSP00000356253	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:elf3_human(display_long)|uniprotkb:ELF3(gene name)|psi-mi:ELF3(display_short)|uniprotkb:ERT(gene name synonym)|uniprotkb:ESX(gene name synonym)|uniprotkb:JEN(gene name synonym)|uniprotkb:E74-like factor 3(gene name synonym)|uniprotkb:Epithelium-specific Ets transcription factor 1(gene name synonym)|uniprotkb:Epithelium-restricted Ets protein ESX(gene name synonym)|uniprotkb:Epithelial-restricted with serine box(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339465|imex:IM-11696-644	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_001107781.1|refseq:NP_004424.3|ensembl:ENSG00000163435(gene)|ensembl:ENST00000359651(transcript)|ensembl:ENST00000367283(transcript)|ensembl:ENST00000367284(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001824"(blastocyst development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060056"(mammary gland involution)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR033074|interpro:IPR036388|interpro:IPR036390|interpro:IPR042693|rcsb pdb:2E8P|reactome:R-HSA-1912408	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:UR/FgxMk+J5InoP/6OCJTyCwM/s9606	intact-crc:C2F78E698FA5BFDD|rigid:S6sFlR9KMOTs6/OhE72bjFsNLRQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99942	uniprotkb:P62837	intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339468|imex:IM-11696-645	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:5C414541C5CA4B32|rigid:UaeMH3s9KJnX68kqAx349kuPmTI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:P62081	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-354360|uniprotkb:Q6IPH1|uniprotkb:P23821|uniprotkb:P24818|uniprotkb:Q57Z92|ensembl:ENSP00000385018|ensembl:ENSP00000385286|ensembl:ENSP00000495273|ensembl:ENSP00000496654|ensembl:ENSP00000496757	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:rs7_human(display_long)|uniprotkb:RPS7(gene name)|psi-mi:RPS7(display_short)|uniprotkb:Small ribosomal subunit protein eS7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339471|imex:IM-11696-646	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_001002.1|ensembl:ENSG00000171863(gene)|ensembl:ENST00000403564(transcript)|ensembl:ENST00000406376(transcript)|ensembl:ENST00000462576(transcript)|ensembl:ENST00000645674(transcript)|ensembl:ENST00000646909(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000554(Ribosomal protein S7e)|mint:P62081|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6G4S	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:l4aG6I34lmzYhNapbdv2CAAwRwg9606	intact-crc:91104E752AFD368C|rigid:N5LUCXNFEqhdt+/z5zhtz//cuzM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14681	uniprotkb:P62837	intact:EBI-2339413|uniprotkb:Q9BUQ1|uniprotkb:A8K7D6|uniprotkb:B4DKL6|ensembl:ENSP00000278903|ensembl:ENSP00000484510	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:ei24_human(display_long)|uniprotkb:EI24(gene name)|psi-mi:EI24(display_short)|uniprotkb:PIG8(gene name synonym)|uniprotkb:p53-induced gene 8 protein(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339474|imex:IM-11696-647	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011541371.1|refseq:NP_001277064.1|refseq:NP_004870.3|ensembl:ENSG00000149547(gene)|ensembl:ENST00000278903(transcript)|ensembl:ENST00000620753(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061676"(importin-alpha family protein binding)|interpro:IPR009890(Etoposide-induced 2.4)|mint:O14681	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:mb5BoJ3ithOKYe8mN+ZRB4UoltI9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:9023345847921043|rigid:N8DDZsmq5WRyKHIq+1n/ZSWJBbQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q86Y13	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339477|imex:IM-11696-648	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:32308CB54B59B962|rigid:2o0YaHFmbO7gla/Q9LykdYsuLYA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5U6	uniprotkb:P62837	intact:EBI-714023|uniprotkb:Q92550|uniprotkb:Q9NPP8|uniprotkb:Q9ULW4|ensembl:ENSP00000322242	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:rnf10_human(display_long)|uniprotkb:RNF10(gene name)|psi-mi:RNF10(display_short)|uniprotkb:KIAA0262(gene name synonym)|uniprotkb:RIE2(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339480|imex:IM-11696-649	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055683.3|refseq:NP_001317403.1|ensembl:ENSG00000022840(gene)|ensembl:ENST00000325954(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039739|mint:Q8N5U6	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Bca0Ae456x1eCsdlduoCbn7coUQ9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:9392EA3B22129F95|rigid:aDBx9duImS0/NTdp7UOJK8mC168	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q9Y3C5	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-396669|intact:EBI-2129167|uniprotkb:A8KAI2|uniprotkb:Q5T7R8|ensembl:ENSP00000242719	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:rnf11_human(display_long)|uniprotkb:CGI-123(orf name)|uniprotkb:RNF11(gene name)|psi-mi:RNF11(display_short)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339483|imex:IM-11696-650	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_055187.1|ensembl:ENSP00000242719|ensembl:ENSG00000123091(gene)|ensembl:ENST00000242719(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042981|mint:Q9Y3C5	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:Uj0YAf/t+AdYbMd6fgQ8hVKoP0w9606	intact-crc:587BEC81F2299A69|rigid:RDLiR+M2V+bH5mdKpAzKPr37IWQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q9BV68	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-357322|ensembl:ENSP00000292363|uniprotkb:Q9NWX1|intact:EBI-11064977	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:rn126_human(display_long)|uniprotkb:RNF126(gene name)|psi-mi:RNF126(display_short)|uniprotkb:RING finger protein 126(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339492|imex:IM-11696-653	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	ensembl:ENSG00000070423(gene)|ensembl:ENST00000292363(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR039525|interpro:IPR039571|interpro:IPR039572|rcsb pdb:2N9O|rcsb pdb:2N9P|reactome:R-HSA-983168|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|refseq:NP_919442.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2019/01/23	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:4Z4AJGHJgoIUp9zhtfWcFBF1Fxw9606	intact-crc:B000A96F51167B5D|rigid:S4TqswCARBkBxllNufpvfgJymss	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q96FW1	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339489|imex:IM-11696-652	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	intact-crc:D0505803BBCBA9E3|rigid:oxS/Sh9yEm54jbxUZtX7Bsx/fZg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NZS9	uniprotkb:P62837	intact:EBI-2130199|uniprotkb:A8K4Z9|uniprotkb:D3DUG8|uniprotkb:B4DUT0|ensembl:ENSP00000261658|ensembl:ENSP00000478190	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:bfar_human(display_long)|uniprotkb:BFAR(gene name)|psi-mi:BFAR(display_short)|uniprotkb:BAR(gene name synonym)|uniprotkb:RNF47(gene name synonym)|uniprotkb:RING finger protein 47(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339486|imex:IM-11696-651	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057645.1|refseq:XP_005255407.1|ensembl:ENSG00000103429(gene)|ensembl:ENSG00000275618(gene)|ensembl:ENST00000261658(transcript)|ensembl:ENST00000619034(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017907	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:XDPFsRmdbch1NXffLOcE0lVrtRo9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:9E73496551DBDF6F|rigid:EsuNfoZ2HiFftkJSKhVoBhM71Fo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y508	uniprotkb:P62837	intact:EBI-723587|uniprotkb:Q6N0B0|uniprotkb:B2RDQ9|uniprotkb:B4DWY5|uniprotkb:E1P627|ensembl:ENSP00000244061	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:rn114_human(display_long)|uniprotkb:Zinc finger protein 313(gene name synonym)|uniprotkb:RNF114(gene name)|psi-mi:RNF114(display_short)|uniprotkb:ZNF313(gene name synonym)|uniprotkb:ZNF228(gene name synonym)|uniprotkb:Zinc finger protein 228(gene name synonym)|uniprotkb:RING finger protein 114(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF114(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339498|imex:IM-11696-655	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061153.1|ensembl:ENSG00000124226(gene)|ensembl:ENST00000244061(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR034734|interpro:IPR042716|reactome:R-HSA-983168	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:R1fX8xaGuIhy/M6cLzPeyfJBf649606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:2C10656C3B8B44FA|rigid:7enwrr3ua8masa6sRDonNzyJxj4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EP1	uniprotkb:P62837	intact:EBI-718923|uniprotkb:A6NEN5|uniprotkb:Q96SL3|uniprotkb:Q9NRT4|uniprotkb:Q9NT32|uniprotkb:Q9NVD5|uniprotkb:B4DZ77|uniprotkb:B4E2L6|ensembl:ENSP00000392395	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:chfr_human(display_long)|uniprotkb:Checkpoint with forkhead and RING finger domains protein(gene name synonym)|uniprotkb:RING finger protein 196(gene name synonym)|uniprotkb:CHFR(gene name)|psi-mi:CHFR(display_short)|uniprotkb:RNF196(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHFR(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339495|imex:IM-11696-654	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154816.1|refseq:NP_001154817.1|refseq:NP_001154818.1|refseq:NP_001154819.1|refseq:NP_060693.2|ensembl:ENSG00000072609(gene)|ensembl:ENST00000432561(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR019406|interpro:IPR040909|rcsb pdb:1LGP|rcsb pdb:1LGQ|rcsb pdb:2XOC|rcsb pdb:2XOY|rcsb pdb:2XOZ|rcsb pdb:2XP0|dip:DIP-40098N	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid://FU72n6rmuPAu+Fjm377S4nEjw9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:5F1CCB6027599AAA|rigid:OP2wbUI7ITjhKjowQuuXeg06TfI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q9P2E3	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-308745|uniprotkb:Q9BQM7|uniprotkb:Q9BQM8|uniprotkb:Q9H8C1|uniprotkb:Q9H9S2|uniprotkb:Q9NUM1|uniprotkb:Q9NWW1|ensembl:ENSP00000360817|ensembl:ENSP00000379412	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:znfx1_human(display_long)|uniprotkb:ZNFX1(gene name)|psi-mi:ZNFX1(display_short)|uniprotkb:KIAA1404(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339501|imex:IM-11696-656	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_066363.1|ensembl:ENSG00000124201(gene)|ensembl:ENST00000371752(transcript)|ensembl:ENST00000396105(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0031380"(nuclear RNA-directed RNA polymerase complex)|interpro:IPR000967(Zinc finger, NF-X1-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|mint:Q9P2E3|refseq:XP_006723899.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:2vNUbYE3//YGh0eabKbzldLESF49606	intact-crc:5F3010086EC46C26|rigid:tJhQCWq0EOIJIKaL29rnQKc+LWg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BY78	uniprotkb:P62837	intact:EBI-2129375|uniprotkb:Q542Y8|intact:EBI-2339452|intact:EBI-28972797|ensembl:ENSP00000312439	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:rnf26_human(display_long)|uniprotkb:RNF26(gene name)|psi-mi:RNF26(display_short)|uniprotkb:RING finger protein 26(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339504|imex:IM-11696-657	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000312439|refseq:NP_114404.1|ensembl:ENSG00000173456(gene)|ensembl:ENST00000311413(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007032"(endosome organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040089	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:R0awMKLLQSLU9zjVe/ivOWeYjnE9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:D23FD932FE665438|rigid:/jDzrhDRJ1hZir7l8tPnRVMlgGs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8ND25	uniprotkb:P62837	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339507|imex:IM-11696-658	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:558EEA518E9F975E|rigid:s+LFkHsZf1nUxmTPCbLhyDRZrW4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:P08708	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-358255|uniprotkb:B2R4U4|intact:EBI-8012092|intact:EBI-11603362|intact:MINT-8395037|uniprotkb:P0CW22|ensembl:ENSP00000483755|ensembl:ENSP00000498019	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:rs17_human(display_long)|uniprotkb:RPS17(gene name)|psi-mi:RPS17(display_short)|uniprotkb:Small ribosomal subunit protein eS17(gene name synonym)|uniprotkb:RPS17L(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339510|imex:IM-11696-659	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_001012.1|ensembl:ENSG00000182774(gene)|ensembl:ENSG00000278229(gene)|ensembl:ENST00000617731(transcript)|ensembl:ENST00000647841(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR001210(Ribosomal protein S17e)|interpro:IPR018273|interpro:IPR036401|mint:P08708|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|go:"GO:0034101"(erythrocyte homeostasis)|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBS|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:st+xQCXdSObiy6cJD1cSx869V289606	intact-crc:174A3BF782057FE8|rigid:8V6EPWTaOXF2Idunkva95MW/o/o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:P46779	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-366357|uniprotkb:Q6IAY0|uniprotkb:Q96FX1|uniprotkb:Q9BWQ0|uniprotkb:B2R4A6|uniprotkb:B4DEP9|uniprotkb:E9PB24|uniprotkb:C9JB50|uniprotkb:G5E9L2|ensembl:ENSP00000342787|ensembl:ENSP00000453319	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:rl28_human(display_long)|uniprotkb:RPL28(gene name)|psi-mi:RPL28(display_short)|uniprotkb:Large ribosomal subunit protein eL28(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339516|imex:IM-11696-661	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:NP_001129608.1|refseq:NP_001129609.1|refseq:NP_000982.2|refseq:NP_001129606.1|refseq:NP_001129607.1|ensembl:ENSG00000108107(gene)|ensembl:ENST00000344063(transcript)|ensembl:ENST00000559463(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002672(Ribosomal protein L28e)|interpro:IPR029004|mint:P46779|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:I7Me1zjfxk98g6C2NoYOWlmrYVc9606	intact-crc:89CC4CC6D865B3BF|rigid:yoxjMhmArxRZExS1JfE2MC2VCP4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q99942	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339513|imex:IM-11696-660	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606	intact-crc:C388F8F404EF905E|rigid:zjux9cYhq7vgGCXRmLAwP8dkakU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NZS9	uniprotkb:P61077	intact:EBI-2130199|uniprotkb:A8K4Z9|uniprotkb:D3DUG8|uniprotkb:B4DUT0|ensembl:ENSP00000261658|ensembl:ENSP00000478190	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:bfar_human(display_long)|uniprotkb:BFAR(gene name)|psi-mi:BFAR(display_short)|uniprotkb:BAR(gene name synonym)|uniprotkb:RNF47(gene name synonym)|uniprotkb:RING finger protein 47(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339519|imex:IM-11696-662	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057645.1|refseq:XP_005255407.1|ensembl:ENSG00000103429(gene)|ensembl:ENSG00000275618(gene)|ensembl:ENST00000261658(transcript)|ensembl:ENST00000619034(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017907	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:XDPFsRmdbch1NXffLOcE0lVrtRo9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:01BAF4D090FE0403|rigid:7dAjHqPLqttimvVpFRZTDlKoD8M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TDN6	uniprotkb:P61077	intact:EBI-1052326|uniprotkb:Q3ZTT4|uniprotkb:Q8N453|uniprotkb:Q96DH1|uniprotkb:A8K0P5|ensembl:ENSP00000338862	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:brx1_human(display_long)|uniprotkb:BRIX1(gene name)|psi-mi:BRIX1(display_short)|uniprotkb:BXDC2(gene name synonym)|uniprotkb:BRIX(gene name synonym)|uniprotkb:Brix domain-containing protein 2(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339522|imex:IM-11696-663	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060791.3|ensembl:ENSG00000113460(gene)|ensembl:ENST00000336767(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|interpro:IPR007109(Brix)|interpro:IPR026532|mint:Q8TDN6	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Xa2UDOXgdmWyJ7qBZsdInDt9Vaw9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:A54C1CE45598246C|rigid:GeBMMvN1mgV1ClfWAsxwa62K6LE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q96FW1	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339525|imex:IM-11696-664	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	intact-crc:4F99E5B67AEE728F|rigid:/LgwsBSJJ4IzjCDfU4+MRN5S+1Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BV68	uniprotkb:P61077	intact:EBI-357322|ensembl:ENSP00000292363|uniprotkb:Q9NWX1|intact:EBI-11064977	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:rn126_human(display_long)|uniprotkb:RNF126(gene name)|psi-mi:RNF126(display_short)|uniprotkb:RING finger protein 126(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339528|imex:IM-11696-665	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000070423(gene)|ensembl:ENST00000292363(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR039525|interpro:IPR039571|interpro:IPR039572|rcsb pdb:2N9O|rcsb pdb:2N9P|reactome:R-HSA-983168|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|refseq:NP_919442.1	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2019/01/23	rogid:4Z4AJGHJgoIUp9zhtfWcFBF1Fxw9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:2FC914DA9033A031|rigid:fmJugtM4WBOn96fZJwoySPRs41k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BY78	uniprotkb:P61077	intact:EBI-2129375|uniprotkb:Q542Y8|intact:EBI-2339452|intact:EBI-28972797|ensembl:ENSP00000312439	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:rnf26_human(display_long)|uniprotkb:RNF26(gene name)|psi-mi:RNF26(display_short)|uniprotkb:RING finger protein 26(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339531|imex:IM-11696-666	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000312439|refseq:NP_114404.1|ensembl:ENSG00000173456(gene)|ensembl:ENST00000311413(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007032"(endosome organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040089	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:R0awMKLLQSLU9zjVe/ivOWeYjnE9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:4DF664873F438F54|rigid:EYhD+hpAxhG6a+RAq11FUFX1G58	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q9UII4	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-2339540|uniprotkb:B2RTQ1|uniprotkb:Q69G20|intact:EBI-28975860|ensembl:ENSP00000264350	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:herc5_human(display_long)|uniprotkb:HERC5(gene name)|psi-mi:HERC5(display_short)|uniprotkb:CEB1(gene name synonym)|uniprotkb:CEBP1(gene name synonym)|uniprotkb:HECT domain and RCC1-like domain-containing protein 5(gene name synonym)|uniprotkb:Cyclin-E-binding protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339545|imex:IM-11696-669	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	ensembl:ENSP00000264350|refseq:NP_057407.2|dip:DIP-44200N|ensembl:ENSG00000138646(gene)|ensembl:ENST00000264350(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000569(HECT)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR035983|mint:Q9UII4|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-936440|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:IGuce5qcdMB8PC5u6b6A57FODKY9606	intact-crc:CF9EA98D2154C528|rigid:SkFB5jKWcaCVasHGZoxZ3XinWY8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q9Y6M9	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-713654|uniprotkb:Q9UQE8|uniprotkb:B2R8M6|ensembl:ENSP00000276689|ensembl:ENSP00000504235	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:ndub9_human(display_long)|uniprotkb:LYRM3(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B22 subunit(gene name synonym)|uniprotkb:Complex I-B22(gene name synonym)|uniprotkb:LYR motif-containing protein 3(gene name synonym)|uniprotkb:NDUFB9(gene name)|psi-mi:NDUFB9(display_short)|uniprotkb:UQOR22(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339537|imex:IM-11696-668	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	rcsb pdb:5XTH|rcsb pdb:5XTD|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000147684(gene)|ensembl:ENST00000276689(transcript)|ensembl:ENST00000677021(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008011(Complex 1 LYR protein)|interpro:IPR033034|mint:Q9Y6M9|rcsb pdb:5XTC|refseq:NP_001298097.1|refseq:NP_004996.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:sNQcYhIFMHZA5T6MeeiwAeAJ5Gs9606	intact-crc:08F06555EEE9610D|rigid:X6nmXEobWXgfk80xh9O3Ddc28yQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8ND25	uniprotkb:P61077	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339534|imex:IM-11696-667	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:CA4757E44FBA4C32|rigid:PKp+UXAyI8kz+DVxHlEfZ9JDoEU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q5VTB9	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-949963|ensembl:ENSP00000347548|ensembl:ENSP00000354872|ensembl:ENSP00000361321|uniprotkb:B3KPJ3|uniprotkb:Q4KMX2|uniprotkb:Q9NVP6|uniprotkb:B4DLZ9|uniprotkb:E9PCS1	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:rn220_human(display_long)|uniprotkb:C1orf164(gene name synonym)|uniprotkb:RNF220(gene name)|psi-mi:RNF220(display_short)|uniprotkb:RING finger protein 220(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF220(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339551|imex:IM-11696-671	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_060620.2|ensembl:ENSG00000187147(gene)|ensembl:ENST00000355387(transcript)|ensembl:ENST00000361799(transcript)|ensembl:ENST00000372247(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031824|interpro:IPR040178|reactome:R-HSA-983168|refseq:NP_001306885.1|refseq:NP_001306886.1|refseq:XP_016857112.1|refseq:XP_016857113.1|refseq:XP_016857114.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:++tO9LPa3Hh0vhx5A1fIyv+5Djc9606	intact-crc:22C1BC8247913AD0|rigid:CGNTejL5LVggHHVF5VZZz7Me8gU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:O95071	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-358329|uniprotkb:O94970|uniprotkb:Q9NPL3|ensembl:ENSP00000429084|uniprotkb:B2RP24|intact:EBI-10967451|uniprotkb:J3KMW7	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:ubr5_human(display_long)|uniprotkb:UBR5(gene name)|psi-mi:UBR5(display_short)|uniprotkb:HYD(gene name synonym)|uniprotkb:KIAA0896(gene name synonym)|uniprotkb:EDD(gene name synonym)|uniprotkb:EDD1(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:Progestin-induced protein(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339548|imex:IM-11696-670	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_001269802.1|ensembl:ENST00000520539(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|ensembl:ENSG00000104517(gene)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|mint:O95071|rcsb pdb:1I2T|rcsb pdb:2QHO|refseq:NP_056986.2|rcsb pdb:3PT3|dip:DIP-32930N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:5yiXAYJbV4iA8d3btwaVfL7vaik9606	intact-crc:9FA1A628E5E4E2B5|rigid:ZHD/Wg1TUyi2QcmbCxIl9Mtyd6o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96FW1	uniprotkb:P51965	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339554|imex:IM-11696-672	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	intact-crc:F3A9E4A1A77C3A42|rigid:thHpPmlLtWF9ZTPZojSS/AWUs2E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVP2	uniprotkb:P51965	intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short)	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339557|imex:IM-11696-673	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	psi-mi:"MI:0469"(intact)	caution:This sequence has been withdrawn from Uniprot.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:gG2Px6QOw95EohRaaWivH7GrSr09606	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	intact-crc:356DE51CE96CFFAF|rigid:WsJjenkFv/ycAfJ42a8S2dFxc/k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5I2	uniprotkb:P51965	intact:EBI-2339564|ensembl:ENSP00000360475	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:arrd1_human(display_long)|uniprotkb:Alpha-arrestin 1(gene name synonym)|uniprotkb:ARRDC1(gene name)|psi-mi:ARRDC1(display_short)	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339563|imex:IM-11696-675	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689498.1|ensembl:ENSP00000360475|ensembl:ENSG00000197070(gene)|ensembl:ENST00000371421(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006858"(extracellular transport)|go:"GO:0015031"(protein transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140112"(extracellular vesicle biogenesis)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Q776M1DBnxGDHoHAqS666mel0hM9606	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	intact-crc:C9A83550FC03EE49|rigid:PRxHSvvB3l5rIFSNTdT4MKrhGBs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BY78	uniprotkb:P51965	intact:EBI-2129375|uniprotkb:Q542Y8|intact:EBI-2339452|intact:EBI-28972797|ensembl:ENSP00000312439	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:rnf26_human(display_long)|uniprotkb:RNF26(gene name)|psi-mi:RNF26(display_short)|uniprotkb:RING finger protein 26(gene name synonym)	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339560|imex:IM-11696-674	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000312439|refseq:NP_114404.1|ensembl:ENSG00000173456(gene)|ensembl:ENST00000311413(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007032"(endosome organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040089	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:R0awMKLLQSLU9zjVe/ivOWeYjnE9606	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	intact-crc:F1C66590E2D1C799|rigid:XtRO9JRHWFhtOOAXkEmV0yPxwwQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99942	uniprotkb:Q96LR5	intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339573|imex:IM-11696-677	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:0FC9BEE08C7F88F7|rigid:nu8BcTVJKrnEEvtTo3E1ZK0fbsA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LR5	uniprotkb:P00338	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-372327|uniprotkb:Q53G53|uniprotkb:Q6IBM7|uniprotkb:Q6ZNV1|ensembl:ENSP00000368722|ensembl:ENSP00000395337|ensembl:ENSP00000445331|ensembl:ENSP00000499898|ensembl:ENSP00000499977|ensembl:ENSP00000500953|uniprotkb:Q9UDE8|uniprotkb:Q9UDE9|uniprotkb:D3DQY3|uniprotkb:B7Z5E3|uniprotkb:B4DKQ2|uniprotkb:F8W819	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:ldha_human(display_long)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-59(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 19 protein(gene name synonym)|uniprotkb:PIG19(orf name)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339570|imex:IM-11696-676	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	refseq:NP_001158886.1|ensembl:ENSG00000134333(gene)|ensembl:ENSG00000288299(gene)|ensembl:ENST00000379412(transcript)|ensembl:ENST00000422447(transcript)|ensembl:ENST00000542179(transcript)|ensembl:ENST00000671981(transcript)|ensembl:ENST00000672405(transcript)|ensembl:ENST00000673204(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045296"(cadherin binding)|go:"GO:0048569"(post-embryonic animal organ development)|go:"GO:0051287"(NAD binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|rcsb pdb:1I10|mint:P00338|rcsb pdb:4AJP|rcsb pdb:4JNK|rcsb pdb:4L4R|rcsb pdb:4L4S|rcsb pdb:4M49|rcsb pdb:4OJN|rcsb pdb:4OKN|rcsb pdb:4QO7|rcsb pdb:4QO8|rcsb pdb:4QSM|rcsb pdb:4QT0|rcsb pdb:4R68|rcsb pdb:4R69|rcsb pdb:4RLS|rcsb pdb:4ZVV|rcsb pdb:5IXS|rcsb pdb:5IXY|rcsb pdb:5W8H|rcsb pdb:5W8I|rcsb pdb:5W8J|rcsb pdb:5W8K|rcsb pdb:5W8L|rcsb pdb:5ZJD|rcsb pdb:5ZJE|rcsb pdb:5ZJF|rcsb pdb:6BAD|rcsb pdb:6BAG|rcsb pdb:6BAX|rcsb pdb:6BAZ|rcsb pdb:6BB0|rcsb pdb:6BB1|rcsb pdb:6BB2|rcsb pdb:6BB3|rcsb pdb:6MV8|rcsb pdb:6MVA|rcsb pdb:6Q0D|rcsb pdb:6SBU|rcsb pdb:6SBV|rcsb pdb:6ZZR|reactome:R-HSA-70268|rcsb pdb:6Q13|refseq:NP_001158887.1|refseq:NP_005557.1|refseq:NP_001128711.1|refseq:NP_001158888.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:Zpq2lAJLPG+q2bMEru3cq7B5gCk9606	intact-crc:C4D94F4E3E0C6EE0|rigid:jpRDAwGEXGeDiCkgGefsxKcEnOo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LR5	uniprotkb:Q9UII4	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-2339540|uniprotkb:B2RTQ1|uniprotkb:Q69G20|intact:EBI-28975860|ensembl:ENSP00000264350	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:herc5_human(display_long)|uniprotkb:HERC5(gene name)|psi-mi:HERC5(display_short)|uniprotkb:CEB1(gene name synonym)|uniprotkb:CEBP1(gene name synonym)|uniprotkb:HECT domain and RCC1-like domain-containing protein 5(gene name synonym)|uniprotkb:Cyclin-E-binding protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339579|imex:IM-11696-679	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	ensembl:ENSP00000264350|refseq:NP_057407.2|dip:DIP-44200N|ensembl:ENSG00000138646(gene)|ensembl:ENST00000264350(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000569(HECT)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR035983|mint:Q9UII4|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-936440|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:IGuce5qcdMB8PC5u6b6A57FODKY9606	intact-crc:BFEFEE8E7456954C|rigid:ifj4Zl+lIxLm7+mzMvM8Lw5u1ao	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86TI0	uniprotkb:Q96LR5	intact:EBI-1644036|uniprotkb:Q96K82|uniprotkb:Q9UPP4|uniprotkb:B7Z3D9|uniprotkb:E9PGH8|ensembl:ENSP00000261439	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:tbcd1_human(display_long)|uniprotkb:TBC1D1(gene name)|psi-mi:TBC1D1(display_short)|uniprotkb:KIAA1108(gene name synonym)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339576|imex:IM-11696-678	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055988.2|refseq:NP_001240841.1|ensembl:ENSG00000065882(gene)|ensembl:ENST00000261439(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021785|interpro:IPR035969|mint:Q86TI0|rcsb pdb:3QYE|reactome:R-HSA-1445148	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:+tRzQ4X+dhS4c3md7N2TaJdHIWY9606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:5BD4097A42634ED9|rigid:s64BQoZ4HLSIBcbEKbmeIgGwnHI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VTB9	uniprotkb:Q96LR5	intact:EBI-949963|ensembl:ENSP00000347548|ensembl:ENSP00000354872|ensembl:ENSP00000361321|uniprotkb:B3KPJ3|uniprotkb:Q4KMX2|uniprotkb:Q9NVP6|uniprotkb:B4DLZ9|uniprotkb:E9PCS1	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:rn220_human(display_long)|uniprotkb:C1orf164(gene name synonym)|uniprotkb:RNF220(gene name)|psi-mi:RNF220(display_short)|uniprotkb:RING finger protein 220(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF220(gene name synonym)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339585|imex:IM-11696-681	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060620.2|ensembl:ENSG00000187147(gene)|ensembl:ENST00000355387(transcript)|ensembl:ENST00000361799(transcript)|ensembl:ENST00000372247(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031824|interpro:IPR040178|reactome:R-HSA-983168|refseq:NP_001306885.1|refseq:NP_001306886.1|refseq:XP_016857112.1|refseq:XP_016857113.1|refseq:XP_016857114.1	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:++tO9LPa3Hh0vhx5A1fIyv+5Djc9606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:45F129030B761CBD|rigid:Z5Z6qj80yac46XEX6wti0bSJeAA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95071	uniprotkb:Q96LR5	intact:EBI-358329|uniprotkb:O94970|uniprotkb:Q9NPL3|ensembl:ENSP00000429084|uniprotkb:B2RP24|intact:EBI-10967451|uniprotkb:J3KMW7	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:ubr5_human(display_long)|uniprotkb:UBR5(gene name)|psi-mi:UBR5(display_short)|uniprotkb:HYD(gene name synonym)|uniprotkb:KIAA0896(gene name synonym)|uniprotkb:EDD(gene name synonym)|uniprotkb:EDD1(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:Progestin-induced protein(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339582|imex:IM-11696-680	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269802.1|ensembl:ENST00000520539(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|ensembl:ENSG00000104517(gene)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|mint:O95071|rcsb pdb:1I2T|rcsb pdb:2QHO|refseq:NP_056986.2|rcsb pdb:3PT3|dip:DIP-32930N	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5yiXAYJbV4iA8d3btwaVfL7vaik9606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:F7CFFD64DE818948|rigid:XS/NixIqPvMJVRpWXXaXkOtPscQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LR5	uniprotkb:Q96J02	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-1564678|uniprotkb:O43584|uniprotkb:Q5TEL0|uniprotkb:Q96F66|uniprotkb:Q9BY75|uniprotkb:Q9H451|uniprotkb:Q9H4U5|uniprotkb:A6NEW4|uniprotkb:Q5QP37|uniprotkb:E1P5P3|uniprotkb:B4E234|uniprotkb:F5H217|ensembl:ENSP00000262650|ensembl:ENSP00000499786	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:itch_human(display_long)|uniprotkb:HECT-type E3 ubiquitin transferase Itchy homolog(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 4(gene name synonym)|uniprotkb:NFE2-associated polypeptide 1(gene name synonym)|uniprotkb:ITCH(gene name)|psi-mi:ITCH(display_short)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339588|imex:IM-11696-682	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	refseq:NP_001311126.1|refseq:NP_113671.3|refseq:NP_001244066.1|refseq:NP_001311127.1|refseq:NP_001244067.1|refseq:XP_016883578.1|refseq:XP_016883580.1|dip:DIP-29849N|ensembl:ENSG00000078747(gene)|ensembl:ENST00000262650(transcript)|ensembl:ENST00000665346(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045236"(CXCR chemokine receptor binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046642"(negative regulation of alpha-beta T cell proliferation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090085"(regulation of protein deubiquitination)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:2000646"(positive regulation of receptor catabolic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:Q96J02|rcsb pdb:2DMV|rcsb pdb:2KYK|rcsb pdb:2NQ3|rcsb pdb:2P4R|rcsb pdb:2YSF|rcsb pdb:3TUG|rcsb pdb:4ROF|rcsb pdb:5C7M|rcsb pdb:5CQ2|rcsb pdb:5DWS|rcsb pdb:5DZD|rcsb pdb:5SXP|reactome:R-HSA-1253288|reactome:R-HSA-168638|reactome:R-HSA-2122948|reactome:R-HSA-5610780|reactome:R-HSA-5632684|reactome:R-HSA-8939236|reactome:R-HSA-936440|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:JyySOfI+ZHOI1mvdxWDGN6njgCY9606	intact-crc:CFE8797F3B7F3F6A|rigid:n5AF8dd0qVv1GncvNhpBlV6aOHs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:Q9Y679	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-1058701|ensembl:ENSP00000366748|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339591|imex:IM-11696-683	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	ensembl:ENSG00000115307(gene)|ensembl:ENST00000377526(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_853553.1|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1990044"(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|rcsb pdb:2EKF	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2018/09/18	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	intact-crc:35E1F39E1B770E9D|rigid:RD4D4Bl0p2TJpdGOw9PoV+PYSeM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:P61326	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-299134|ensembl:ENSP00000360525|uniprotkb:O35169|uniprotkb:P50606|uniprotkb:Q5SW69|uniprotkb:B2R5A2|uniprotkb:B1ARP8	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:mgn_human(display_long)|uniprotkb:MAGOH(gene name)|psi-mi:MAGOH(display_short)|uniprotkb:MAGOHA(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339594|imex:IM-11696-684	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	ensembl:ENSG00000162385(gene)|ensembl:ENST00000371470(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004023(Mago nashi protein)|interpro:IPR036605|mint:P61326|rcsb pdb:1P27|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:7A5P|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|refseq:NP_002361.1|dip:DIP-33069N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:QwhNt2LtYudXCggVAqBsZm/hWAA9606	intact-crc:10980B8C5A1E9B28|rigid:WyZZ8UvNiEDA5RCgpOlwh+ApziM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:B2RDW1	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-2339597|uniprotkb:D6W5C9	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:b2rdw1_human(display_long)|uniprotkb:HEL112(gene name)|psi-mi:HEL112(display_short)|uniprotkb:RPS27A(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym)|uniprotkb:Ubiquitin-40S ribosomal protein S27a(gene name synonym)|uniprotkb:hCG_1987923(orf name)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339601|imex:IM-11696-685	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_001129064.1|refseq:NP_001170884.1|refseq:NP_002945.1|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR038582|interpro:IPR029071|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0046872"(metal ion binding)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:2LSJafy6vjKHYZcZVx8zZaOXRis9606	intact-crc:42524A79E643A17F|rigid:x0e2KDqmvP4u5Pzb8nWciZYQfzc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:Q5U5U6	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-1642104	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:q5u5u6_human(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:HEL-S-50(gene name synonym)|uniprotkb:hCG_1998947(orf name)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339604|imex:IM-11696-686	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_061828.1|refseq:NP_001268645.1|refseq:NP_001268646.1|refseq:NP_001268647.1|refseq:NP_001268648.1|refseq:NP_001268649.1|dip:DIP-29136N|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0060613"(fat pad development)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:X2Y1hzv2uGZd9FObQD2Qq3SECRo9606	intact-crc:13FF7DFDF4CFCF21|rigid:HP86Fjt4Lio/BS0am/OurkRTiA8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z6Z7	uniprotkb:Q969T4	intact:EBI-625934|uniprotkb:O15029|uniprotkb:Q4G2Z2|uniprotkb:Q5H961|uniprotkb:Q6P4D0|uniprotkb:Q8NG67|uniprotkb:Q9BUI0|uniprotkb:Q9HCJ4|uniprotkb:Q9NSL6|uniprotkb:Q9P0A9|ensembl:ENSP00000262854|ensembl:ENSP00000340648	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	psi-mi:huwe1_human(display_long)|uniprotkb:HECT, UBA and WWE domain-containing protein 1(gene name synonym)|uniprotkb:Upstream regulatory element-binding protein 1(gene name synonym)|uniprotkb:Mcl-1 ubiquitin ligase E3(gene name synonym)|uniprotkb:ARF-binding protein 1(gene name synonym)|uniprotkb:Large structure of UREB1(gene name synonym)|uniprotkb:Homologous to E6AP carboxyl terminus homologous protein 9(gene name synonym)|uniprotkb:HUWE1(gene name)|psi-mi:HUWE1(display_short)|uniprotkb:KIAA0312(gene name synonym)|uniprotkb:KIAA1578(gene name synonym)|uniprotkb:HSPC272(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase HUWE1(gene name synonym)|uniprotkb:UREB1(gene name synonym)	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339614|imex:IM-11696-688	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000086758(gene)|ensembl:ENST00000262854(transcript)|ensembl:ENST00000342160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007030"(Golgi organization)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR009060(UBA-like)|interpro:IPR010309(E3 ubiquitin ligase, region of unknown function DUF908)|interpro:IPR010314(E3 ubiquitin ligase, region of unknown function DUF913)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025527|interpro:IPR035983|interpro:IPR037197|interpro:IPR041918|mint:Q7Z6Z7|rcsb pdb:2EKK|rcsb pdb:2MUL|rcsb pdb:3G1N|go:"GO:0061025"(membrane fusion)|rcsb pdb:5C6H|rcsb pdb:5LP8|rcsb pdb:6FYH|rcsb pdb:6MIW|rcsb pdb:6PFL|reactome:R-HSA-6798695|rcsb pdb:3H1D|reactome:R-HSA-983168|refseq:NP_113584.3|refseq:XP_005262022.1|dip:DIP-34362N	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:TnIn0mcFc81bJlMkyWTtq3n/uOg9606	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	intact-crc:82A3B885E9F340C4|rigid:s6Epg/JW7sm+7+gLR/4nRE1OWzs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A8CGI2	uniprotkb:Q969T4	intact:EBI-2339607	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	psi-mi:a8cgi2_human(display_long)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339611|imex:IM-11696-687	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR029071|go:"GO:0005765"(lysosomal membrane)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:2Xcg1HzWt50un+IczXX2e3Cdvag9606	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	intact-crc:6D3395D881DD59C1|rigid:TS/zgcPRtZuNI5oqHTtIskwRKP0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13105	uniprotkb:P62256	intact:EBI-372156|uniprotkb:A0AV07|uniprotkb:Q15932|uniprotkb:Q5JYB2|uniprotkb:B4DXB4|uniprotkb:F5H411|uniprotkb:Q9NUC9|uniprotkb:B7ZLQ9|ensembl:ENSP00000364895	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	psi-mi:zbt17_human(display_long)|uniprotkb:ZBTB17(gene name)|psi-mi:ZBTB17(display_short)|uniprotkb:MIZ1(gene name synonym)|uniprotkb:Zinc finger protein 60(gene name synonym)|uniprotkb:Zinc finger protein 151(gene name synonym)|uniprotkb:Myc-interacting zinc finger protein 1(gene name synonym)|uniprotkb:ZNF151(gene name synonym)|uniprotkb:ZNF60(gene name synonym)	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339620|imex:IM-11696-690	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011540390.1|refseq:NP_001229813.1|refseq:NP_003434.2|refseq:NP_001274532.1|ensembl:ENSG00000116809(gene)|ensembl:ENST00000375743(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007398"(ectoderm development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q13105|rcsb pdb:2LVR|rcsb pdb:2LVT|rcsb pdb:2LVU|rcsb pdb:2M0D|rcsb pdb:2M0E|rcsb pdb:2M0F|rcsb pdb:2N25|rcsb pdb:2N26|rcsb pdb:2Q81|rcsb pdb:3M52|rcsb pdb:4U2M|rcsb pdb:4U2N|rcsb pdb:5ION|rcsb pdb:7MC1|rcsb pdb:7MC2|rcsb pdb:7MC3|reactome:R-HSA-381038|dip:DIP-5968N	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:UnpKBOl8g2pZRvmUJDyE3fN7VCg9606	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	intact-crc:EE0ADFB1C9B240B9|rigid:UwPCEt9LNQggjTXTe5LNPIQQmhw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:P49366	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-741925|ensembl:ENSP00000210060|uniprotkb:Q13184|uniprotkb:Q13276|uniprotkb:A8K688|uniprotkb:Q9UDG0|uniprotkb:M0R1I5	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:dhys_human(display_long)|uniprotkb:DHPS(gene name)|psi-mi:DHPS(display_short)|uniprotkb:DS(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339617|imex:IM-11696-689	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_001193903.1|ensembl:ENSG00000095059(gene)|ensembl:ENST00000210060(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008216"(spermidine metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008612"(peptidyl-lysine modification to peptidyl-hypusine)|go:"GO:0034038"(deoxyhypusine synthase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR002773(Deoxyhypusine synthase)|interpro:IPR029035|interpro:IPR036982|mint:P49366|rcsb pdb:1DHS|rcsb pdb:1RLZ|rcsb pdb:1ROZ|rcsb pdb:1RQD|refseq:NP_001921.1|refseq:NP_037538.1|rcsb pdb:6P4V|rcsb pdb:6PGR|rcsb pdb:6WKZ|rcsb pdb:6WL6|rcsb pdb:6XXH|rcsb pdb:6XXI|rcsb pdb:6XXJ|rcsb pdb:6XXK|rcsb pdb:6XXL|rcsb pdb:6XXM|reactome:R-HSA-204626|refseq:XP_011526072.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:4MuV3m6JWYn3kCENrfcLU6GAkto9606	intact-crc:594F3E9D9CFC7CC6|rigid:sjMcQNgpMS9AEQhTMs+lmaNyBTw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:O00429	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339623|imex:IM-11696-691	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N	psi-mi:"MI:0469"(intact)	-	crc64:F9521A376B785B71	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606	intact-crc:22A30B2AC9B3A78E|rigid:sG0s/U+l8yBLOsMUl7MXGHFXxII	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:Q92905	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-594661|uniprotkb:O15386|uniprotkb:Q6AW95|uniprotkb:Q86WQ4|uniprotkb:Q9BQ17|ensembl:ENSP00000350512	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:csn5_human(display_long)|uniprotkb:Jun activation domain-binding protein 1(gene name synonym)|uniprotkb:COPS5(gene name)|psi-mi:COPS5(display_short)|uniprotkb:CSN5(gene name synonym)|uniprotkb:JAB1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339626|imex:IM-11696-692	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_006828.2|dip:DIP-34546N|ensembl:ENSG00000121022(gene)|ensembl:ENST00000357849(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1990182"(exosomal secretion)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|interpro:IPR040961|mint:Q92905|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4F7O|rcsb pdb:4WSN|rcsb pdb:5JOG|rcsb pdb:5JOH|rcsb pdb:5M5Q|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:GMgH8dW3KWILX6Mr/+XrgAV3xY49606	intact-crc:3B799C49849C3B74|rigid:/ro91dZbKxrCnSUtMmw2s2RIEw8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:Q9Y613	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-348433|ensembl:ENSP00000258201|uniprotkb:Q59F76|uniprotkb:Q6Y1F2|uniprotkb:Q76MS8|uniprotkb:Q8N521	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:fhod1_human(display_long)|uniprotkb:FHOD1(gene name)|psi-mi:FHOD1(display_short)|uniprotkb:FHOS(gene name synonym)|uniprotkb:FHOS1(gene name synonym)|uniprotkb:Formin homolog overexpressed in spleen 1(gene name synonym)|uniprotkb:Formin homology 2 domain-containing protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339629|imex:IM-11696-693	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_037373.2|ensembl:ENSG00000135723(gene)|ensembl:ENST00000258201(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007097"(nuclear migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032059"(bleb)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051015"(actin filament binding)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0051660"(establishment of centrosome localization)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027647|interpro:IPR041387|interpro:IPR042201|rcsb pdb:3DAD|rcsb pdb:6XF1|rcsb pdb:6XF2|mint:Q9Y613|dip:DIP-31134N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:8zGurHJ5FL9gvqZazyRAHElMAdI9606	intact-crc:17460C30D77C6F0D|rigid:0jrrJgIzxReubeanszacDqd/JQM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96DV4	uniprotkb:P62256	intact:EBI-720441|uniprotkb:Q96Q66|uniprotkb:Q9P0B9|uniprotkb:B3KN96|ensembl:ENSP00000308275	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	psi-mi:rm38_human(display_long)|uniprotkb:MRPL38(gene name)|psi-mi:MRPL38(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein mL38(gene name synonym)|uniprotkb:HSPC262(orf name)	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339632|imex:IM-11696-694	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115867.2|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|rcsb pdb:6ZSC|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000204316(gene)|ensembl:ENST00000309352(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|mint:Q96DV4|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:U9R8ZJYdURLjkBNd5LZOt4wsWD89606	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	intact-crc:F0FB358F1898D881|rigid:4ch09EJXP5mqcb1syFpJjH/Z4+o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q9H307	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-681904|uniprotkb:Q9UQR9|uniprotkb:O60899|uniprotkb:Q53EM7|uniprotkb:Q6P5X4|uniprotkb:Q7KYL1|uniprotkb:Q99738|uniprotkb:Q9UHZ9|uniprotkb:B4DZX8|ensembl:ENSP00000216832	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:pinin_human(display_long)|uniprotkb:140 kDa nuclear and cell adhesion-related phosphoprotein(gene name synonym)|uniprotkb:Domain-rich serine protein(gene name synonym)|uniprotkb:Melanoma metastasis clone A protein(gene name synonym)|uniprotkb:Desmosome-associated protein(gene name synonym)|uniprotkb:SR-like protein(gene name synonym)|uniprotkb:Nuclear protein SDK3(gene name synonym)|uniprotkb:PNN(gene name)|psi-mi:PNN(display_short)|uniprotkb:DRS(gene name synonym)|uniprotkb:MEMA(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339638|imex:IM-11696-696	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_002678.2|dip:DIP-32950N|ensembl:ENSG00000100941(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030057"(desmosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006786(Pinin/SDK/memA protein)|interpro:IPR006787(Pinin/SDK)|interpro:IPR039853|mint:Q9H307|ensembl:ENST00000216832(transcript)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2018/04/06	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:1pAhD0z8tks+HkWaYWkdMmSjk3s9606	intact-crc:8928CEA08199C270|rigid:oBJwZ15ZFCfrmUDFUKAUj7hLQtM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06265	uniprotkb:P63279	intact:EBI-347966|ensembl:ENSP00000243498|uniprotkb:Q12883|uniprotkb:Q86Y41|uniprotkb:Q86Y48|uniprotkb:Q4W5P5	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:exos9_human(display_long)|uniprotkb:EXOSC9(gene name)|psi-mi:EXOSC9(display_short)|uniprotkb:PMSCL1(gene name synonym)|uniprotkb:Exosome component 9(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Autoantigen PM/Scl 1(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 75 kDa(gene name synonym)|uniprotkb:P75 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339635|imex:IM-11696-695	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006955"(immune response)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|mint:Q06265|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|ensembl:ENSG00000123737(gene)|ensembl:ENST00000243498(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|refseq:NP_001029366.1|refseq:NP_005024.2|dip:DIP-31286N	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:COzGZISdlfGlht1FhyxPhzbV9hY9606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:8BA27F0AAD8F4D3F|rigid:bftG1266ZzcFC9Ugt6LMNxMX/oo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46060	uniprotkb:P63279	intact:EBI-396091|uniprotkb:Q96JJ2|ensembl:ENSP00000401470|ensembl:ENSP00000348577|ensembl:ENSP00000385866	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:ragp1_human(display_long)|uniprotkb:RANGAP1(gene name)|psi-mi:RANGAP1(display_short)|uniprotkb:KIAA1835(gene name synonym)|uniprotkb:SD(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339641|imex:IM-11696-697	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002874.1|ensembl:ENST00000356244(transcript)|ensembl:ENST00000405486(transcript)|ensembl:ENST00000455915(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016235"(aggresome)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:XP_011528596.1|refseq:XP_011528597.1|refseq:NP_001304859.1|go:"GO:0031965"(nuclear membrane)|interpro:IPR009109(Ran-GTPase activating protein 1, C-terminal)|interpro:IPR032675|interpro:IPR036720|mint:P46060|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2IO2|rcsb pdb:2IO3|rcsb pdb:2IY0|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:5D2M|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-2467813|interpro:IPR001611(Leucine-rich repeat)|reactome:R-HSA-2500257|reactome:R-HSA-3108232|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045296"(cadherin binding)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENSG00000100401(gene)|refseq:XP_006724352.1|reactome:R-HSA-4615885|refseq:NP_001265580.1|reactome:R-HSA-68877|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_016884382.1|refseq:XP_016884383.1|refseq:XP_016884384.1|refseq:XP_016884385.1|refseq:XP_016884386.1|dip:DIP-29079N	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pUpd+7p5CeAKaRGLo/bXTeiwjiM9606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:07ED42F5C61B2C6C|rigid:kiYS1fInbf6ZgoEFZHNClxX2jLc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:O75928	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-348555|uniprotkb:O75927|uniprotkb:Q96BT5|uniprotkb:Q96KE3|ensembl:ENSP00000465676	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:pias2_human(display_long)|uniprotkb:Protein inhibitor of activated STAT x(gene name synonym)|uniprotkb:Msx-interacting zinc finger protein(gene name synonym)|uniprotkb:DAB2-interacting protein(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 3(gene name synonym)|uniprotkb:PIAS-NY protein(gene name synonym)|uniprotkb:PIAS2(gene name)|psi-mi:PIAS2(display_short)|uniprotkb:Protein inhibitor of activated STAT2(gene name synonym)|uniprotkb:PIASX(gene name synonym)|uniprotkb:E3 SUMO-protein transferase PIAS2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339644|imex:IM-11696-698	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_004662.2|refseq:NP_775298.1|refseq:NP_001310989.1|ensembl:ENSG00000078043(gene)|ensembl:ENST00000585916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027228|interpro:IPR036361|interpro:IPR038654|mint:O75928|rcsb pdb:2ASQ|rcsb pdb:4FO9|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-4090294	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:/7gObRzCbafNTNMKe8leGG/h2NQ9606	intact-crc:8BDDDD7605B0CC22|rigid:aq73I1pVxsfMvK82F4kfaOoBusw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q15047	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-79691|ensembl:ENSP00000271640|uniprotkb:A6NEW2|uniprotkb:Q5SZD8|uniprotkb:Q5SZD9|uniprotkb:Q5SZE0|uniprotkb:Q5SZE7|uniprotkb:Q96GM9	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:setb1_human(display_long)|uniprotkb:SETDB1(gene name)|psi-mi:SETDB1(display_short)|uniprotkb:KIAA0067(gene name synonym)|uniprotkb:KMT1E(gene name synonym)|uniprotkb:SET domain bifurcated 1(gene name synonym)|uniprotkb:ERG-associated protein with SET domain(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 4(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1E(gene name synonym)|uniprotkb:ESET(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339647|imex:IM-11696-699	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	ensembl:ENSG00000143379(gene)|ensembl:ENST00000271640(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0005694"(chromosome)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033273"(response to vitamin)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045471"(response to ethanol)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002999(Tudor)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR025796|interpro:IPR040880|interpro:IPR041291|interpro:IPR041292|mint:Q15047|rcsb pdb:3DLM|rcsb pdb:4X3S|rcsb pdb:5KCH|rcsb pdb:5KCO|rcsb pdb:5KE2|rcsb pdb:5KE3|rcsb pdb:5KH6|rcsb pdb:5QT1|rcsb pdb:5QT2|rcsb pdb:6AU2|rcsb pdb:6AU3|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6BPI|rcsb pdb:7C9N|rcsb pdb:7CAJ|rcsb pdb:7CD9|rcsb pdb:7CJT|reactome:R-HSA-3214841|refseq:NP_001138887.1|refseq:NP_001230420.1|refseq:NP_036564.3|refseq:XP_016858444.1|dip:DIP-31029N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:ydyGndAZ5b35jF07y4WFUeHFFvE9606	intact-crc:40A9CEC70AB5E518|rigid:6pSfQUVAiaL1fJEZOyhhnA8vzEs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKL3	uniprotkb:P63279	intact:EBI-2339650|uniprotkb:Q6PH76|uniprotkb:Q9NZV9|uniprotkb:Q86YD9|uniprotkb:Q9P2N1|uniprotkb:Q9NUQ4|uniprotkb:Q7LCQ7|uniprotkb:Q9Y563|uniprotkb:A2RUB7|uniprotkb:E1P553	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:c8ap2_human(display_long)|uniprotkb:CASP8AP2(gene name)|psi-mi:CASP8AP2(display_short)|uniprotkb:FLASH(gene name synonym)|uniprotkb:KIAA1315(gene name synonym)|uniprotkb:RIP25(gene name synonym)|uniprotkb:FLICE-associated huge protein(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339662|imex:IM-11696-700	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001131139.1|refseq:NP_001131140.1|refseq:NP_036247.1|mint:Q9UKL3|dip:DIP-40986N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0016505"(peptidase activator activity involved in apoptotic process)|go:"GO:0016605"(PML body)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0036337"(Fas signaling pathway)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR009057(Homeodomain-like)|interpro:IPR039674|rcsb pdb:2LR8|rcsb pdb:6ANO|rcsb pdb:6AOZ|rcsb pdb:6AP0|reactome:R-HSA-3899300	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:MRT84GftrXoJmhrsnUtfJGFhPQQ9606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:3A8E900595EE52F3|rigid:fBAqV7iBMUZIEtr/ogRVDfYTDMo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5T6S3	uniprotkb:P63279	intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339683|imex:IM-11696-702	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:8439A6546E5E8B05|rigid:/vy/7MTuXlaSj58qUy4jK6nucF0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q9Y692	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-2339665|uniprotkb:Q9UKD0|uniprotkb:Q9NWH1|uniprotkb:B1AT48|ensembl:ENSP00000294409	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:gmeb1_human(display_long)|uniprotkb:GMEB1(gene name)|psi-mi:GMEB1(display_short)|uniprotkb:Parvovirus initiation factor p96(gene name synonym)|uniprotkb:DNA-binding protein p96PIF(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339671|imex:IM-11696-701	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:XP_011538820.1|refseq:XP_011538821.1|refseq:XP_011538823.1|refseq:NP_006573.2|refseq:NP_077808.1|refseq:NP_001306603.1|refseq:XP_016855576.1|ensembl:ENSG00000162419(gene)|ensembl:ENST00000294409(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051008"(Hsp27 protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000770(SAND)|interpro:IPR010919(SAND-like)|interpro:IPR024830|mint:Q9Y692|rcsb pdb:1OQJ	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:rmXQXxKkekYnF6K0b24+qYURE8g9606	intact-crc:02B5DF856D8B66E4|rigid:aJTN+XMdZVJ/ETQFkxW34cTCd+E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q9NPI1	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-711221|uniprotkb:Q4VC09|uniprotkb:Q8N2L9|uniprotkb:Q96KA4|uniprotkb:Q9BV48|uniprotkb:Q9UH59|intact:EBI-2560548|ensembl:ENSP00000378180	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:brd7_human(display_long)|uniprotkb:75 kDa bromodomain protein(gene name synonym)|uniprotkb:Protein CELTIX-1(gene name synonym)|uniprotkb:BRD7(gene name)|psi-mi:BRD7(display_short)|uniprotkb:BP75(gene name synonym)|uniprotkb:CELTIX1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339689|imex:IM-11696-704	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_001167455.1|refseq:NP_037395.2|dip:DIP-32509N|ensembl:ENSG00000166164(gene)|ensembl:ENST00000394688(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001487(Bromodomain)|interpro:IPR021900|interpro:IPR036427|mint:Q9NPI1|rcsb pdb:2I7K|rcsb pdb:5MQ1|rcsb pdb:6PPA|rcsb pdb:6V0Q|rcsb pdb:6V16|rcsb pdb:6V17|rcsb pdb:6V1E|rcsb pdb:6V1F|rcsb pdb:6V1H|reactome:R-HSA-6804758	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:F1N3XsdbpPy8TgHdMLSmnhdKNYs9606	intact-crc:35D03F1F31F0C967|rigid:FuswpOMtVaG+bWE5RKDtCqXO8uo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H2X6	uniprotkb:P63279	intact:EBI-348345|ensembl:ENSP00000385571|uniprotkb:Q75MR7|uniprotkb:Q8WWI4|uniprotkb:Q9H2Y1	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:hipk2_human(display_long)|uniprotkb:HIPK2(gene name)|psi-mi:HIPK2(display_short)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339686|imex:IM-11696-703	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0030578"(PML body organization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046332"(SMAD binding)|go:"GO:0046790"(virion binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|rcsb pdb:6P5S|rcsb pdb:7NCF|reactome:R-HSA-2032785|reactome:R-HSA-3899300|reactome:R-HSA-5578768|reactome:R-HSA-6804756|reactome:R-HSA-8939243|reactome:R-HSA-9022692|mint:Q9H2X6|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010842"(retina layer formation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|ensembl:ENSG00000064393(gene)|ensembl:ENST00000406875(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0001654"(eye development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001106710.1|refseq:NP_073577.3|ensembl:ENSP00000385571|ensembl:ENST00000428878|ensembl:ENSP00000413724|dip:DIP-31716N	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jCklf83jA3PA1CGAimi3q9E9CW49606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:57276AA53E525B6A|rigid:dD3Ol1aAVhLCuPDVFfMvThV6BNI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96RL1	uniprotkb:P63279	intact:EBI-725300|intact:EBI-1263554|uniprotkb:Q5XKQ1|uniprotkb:Q7Z3W7|uniprotkb:Q8N5B9|uniprotkb:Q9BZR1|uniprotkb:Q9BZR5|uniprotkb:Q9UHX7|uniprotkb:A8MSA1|uniprotkb:B3KMZ1|uniprotkb:B4E3N2|ensembl:ENSP00000366434|ensembl:ENSP00000421926	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:uimc1_human(display_long)|uniprotkb:Retinoid X receptor-interacting protein 110(gene name synonym)|uniprotkb:Receptor-associated protein 80(gene name synonym)|uniprotkb:Ubiquitin interaction motif-containing protein 1(gene name synonym)|uniprotkb:UIMC1(gene name)|psi-mi:UIMC1(display_short)|uniprotkb:RAP80(gene name synonym)|uniprotkb:RXRIP110(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339692|imex:IM-11696-705	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186226.1|refseq:NP_001186227.1|refseq:NP_057374.3|refseq:NP_001304890.1|ensembl:ENSG00000087206(gene)|ensembl:ENST00000377227(transcript)|ensembl:ENST00000511320(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016604"(nuclear body)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0070531"(BRCA1-A complex)|go:"GO:0070537"(histone H2A K63-linked deubiquitination)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR038868|interpro:IPR040714|mint:Q96RL1|rcsb pdb:2MKF|rcsb pdb:2MKG|rcsb pdb:2N9E|rcsb pdb:2RR9|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_005265987.1|refseq:XP_005265993.1|refseq:XP_006714934.1|refseq:XP_016865063.1|refseq:XP_016865067.1|refseq:XP_016865068.1|dip:DIP-29936N	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:j5ho+aD4tkX7bXXlROdiprUX1Mc9606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:D3E8A23EE3EC583D|rigid:shj4ezIb2VzBmtMo7KI4YulG20g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVP2	uniprotkb:P63279	intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339695|imex:IM-11696-706	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	psi-mi:"MI:0469"(intact)	caution:This sequence has been withdrawn from Uniprot.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:gG2Px6QOw95EohRaaWivH7GrSr09606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:83199CD058C7D9B4|rigid:VBe98/wLsT9KCsNGkB1M+h1SB4s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P68036	uniprotkb:Q96EQ8	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339704|imex:IM-11696-709	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	intact-crc:DBE35FE52F93F544|rigid:uM05WosGxcNY8/Bw23G+nx347aI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P68036	uniprotkb:O95376	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	intact:EBI-711158|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9|ensembl:ENSP00000348769|ensembl:ENSP00000403222	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339701|imex:IM-11696-708	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|ensembl:ENSG00000177479(gene)|ensembl:ENST00000356401(transcript)|ensembl:ENST00000449376(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|refseq:XP_016861020.1|refseq:XP_016861021.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	intact-crc:55A8E0463FD1E530|rigid:fxvoJldDk1ywiJg/lEXiNgn6mP8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P84098	uniprotkb:P68036	intact:EBI-916524|uniprotkb:P14118|uniprotkb:P22908|uniprotkb:Q502Y6|uniprotkb:Q7Z6E4|uniprotkb:B2R4K2|ensembl:ENSP00000225430	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	psi-mi:rl19_human(display_long)|uniprotkb:RPL19(gene name)|psi-mi:RPL19(display_short)|uniprotkb:Large ribosomal subunit protein eL19(gene name synonym)	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339698|imex:IM-11696-707	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000972.1|ensembl:ENSG00000108298(gene)|ensembl:ENST00000225430(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0097421"(liver regeneration)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR000196(Ribosomal protein L19/L19e)|interpro:IPR015972(Ribosomal protein L19/L19e, domain 1)|interpro:IPR023638|interpro:IPR033935|interpro:IPR035970|interpro:IPR039547|mint:P84098|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:sYEwdB8ySbxh3iL0uqlfRRVFiWw9606	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	intact-crc:CA2DE9D2E6E155F5|rigid:sMYZaglqaO7LKcfvN+9G/SCKT/A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86Y13	uniprotkb:P61088	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339710|imex:IM-11696-710	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	intact-crc:969483B23CA70C8B|rigid:SbISQGetu0odgk9ZROwA5X/FSuY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q15819	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-714329|ensembl:ENSP00000428209	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339707|imex:IM-11696-581	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606	intact-crc:4C9BF2EE49009C88|rigid:Fp0VcGxFrfD/I8rZl3eRBEHC93Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q96EP1	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-718923|uniprotkb:A6NEN5|uniprotkb:Q96SL3|uniprotkb:Q9NRT4|uniprotkb:Q9NT32|uniprotkb:Q9NVD5|uniprotkb:B4DZ77|uniprotkb:B4E2L6|ensembl:ENSP00000392395	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:chfr_human(display_long)|uniprotkb:Checkpoint with forkhead and RING finger domains protein(gene name synonym)|uniprotkb:RING finger protein 196(gene name synonym)|uniprotkb:CHFR(gene name)|psi-mi:CHFR(display_short)|uniprotkb:RNF196(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHFR(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339716|imex:IM-11696-712	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	refseq:NP_001154816.1|refseq:NP_001154817.1|refseq:NP_001154818.1|refseq:NP_001154819.1|refseq:NP_060693.2|ensembl:ENSG00000072609(gene)|ensembl:ENST00000432561(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR019406|interpro:IPR040909|rcsb pdb:1LGP|rcsb pdb:1LGQ|rcsb pdb:2XOC|rcsb pdb:2XOY|rcsb pdb:2XOZ|rcsb pdb:2XP0|dip:DIP-40098N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid://FU72n6rmuPAu+Fjm377S4nEjw9606	intact-crc:FBB8C46750A72F43|rigid:wSuzLOV2BUypTBNuU5S6QdRF9EY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q9NZS9	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-2130199|uniprotkb:A8K4Z9|uniprotkb:D3DUG8|uniprotkb:B4DUT0|ensembl:ENSP00000261658|ensembl:ENSP00000478190	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:bfar_human(display_long)|uniprotkb:BFAR(gene name)|psi-mi:BFAR(display_short)|uniprotkb:BAR(gene name synonym)|uniprotkb:RNF47(gene name synonym)|uniprotkb:RING finger protein 47(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339713|imex:IM-11696-711	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	refseq:NP_057645.1|refseq:XP_005255407.1|ensembl:ENSG00000103429(gene)|ensembl:ENSG00000275618(gene)|ensembl:ENST00000261658(transcript)|ensembl:ENST00000619034(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017907	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid:XDPFsRmdbch1NXffLOcE0lVrtRo9606	intact-crc:3AD7466226256A86|rigid:GYUrltwbRA69Ul1RvFAHHu17YBU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q8ND25	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339719|imex:IM-11696-713	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	intact-crc:F12AE556F96122B7|rigid:qTf7IGTbFoOBDbMBjLDpRO67mzk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q13404	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339722|imex:IM-11696-714	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	intact-crc:10A56362AC01C763|rigid:JKeahoWEeK34vp8PtRr4pIuyr6k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13404	uniprotkb:P61088	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339725|imex:IM-11696-715	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	intact-crc:9A5E89C3F110DD83|rigid:JKeahoWEeK34vp8PtRr4pIuyr6k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15819	uniprotkb:Q13424	intact:EBI-714329|ensembl:ENSP00000428209	intact:EBI-717191|intact:EBI-28985258|ensembl:ENSP00000217381|uniprotkb:Q16438|uniprotkb:A8K7H9|uniprotkb:E1P5N1|uniprotkb:B4DX40	psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym)	psi-mi:snta1_human(display_long)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)|uniprotkb:SNTA1(gene name)|psi-mi:SNTA1(display_short)|uniprotkb:SNT1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339728|imex:IM-11696-716	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N	ensembl:ENSG00000101400(gene)|ensembl:ENST00000217381(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|refseq:NP_003089.1|ensembl:ENSP00000217381|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|dip:DIP-966N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606	rogid:ZeVEy6ZeNSJx2vwfHg0WaEu80OE9606	intact-crc:632ECAF27C61CEDB|rigid:IBb3Y/PcdsyS9gaM4uk0GaBJsmA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15819	uniprotkb:P61088	intact:EBI-714329|ensembl:ENSP00000428209	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339731|imex:IM-11696-717	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	intact-crc:C660184F14118668|rigid:Fp0VcGxFrfD/I8rZl3eRBEHC93Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15819	uniprotkb:P54578	intact:EBI-714329|ensembl:ENSP00000428209	intact:EBI-1048016|uniprotkb:Q53XY5|uniprotkb:B7Z4N8|uniprotkb:J3QRZ5|ensembl:ENSP00000261601	psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym)	psi-mi:ubp14_human(display_long)|uniprotkb:USP14(gene name)|psi-mi:USP14(display_short)|uniprotkb:TGT(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 14(gene name synonym)|uniprotkb:Deubiquitinating enzyme 14(gene name synonym)|uniprotkb:Ubiquitin thioesterase 14(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339734|imex:IM-11696-718	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N	refseq:NP_001032411.1|refseq:NP_005142.1|ensembl:ENSG00000101557(gene)|ensembl:ENST00000261601(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0045087"(innate immune response)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR019954|interpro:IPR028889|interpro:IPR029071|interpro:IPR038765|interpro:IPR044635|mint:P54578|rcsb pdb:2AYN|rcsb pdb:2AYO|rcsb pdb:5GJQ|rcsb pdb:6IIK|rcsb pdb:6IIL|rcsb pdb:6IIM|rcsb pdb:6IIN|rcsb pdb:6LVS|reactome:R-HSA-5689880|go:"GO:0070628"(proteasome binding)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606	rogid:5hXfHmHds5nuvdlFYWoB/G6nvmk9606	intact-crc:EA7C05648580156B|rigid:MG9j+kw3ZTcBDhdpKppOE3zBv0c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EH3	uniprotkb:Q15819	intact:EBI-2339737|uniprotkb:A4D154|ensembl:ENSP00000419370	intact:EBI-714329|ensembl:ENSP00000428209	psi-mi:masu1_human(display_long)|uniprotkb:MALSU1(gene name)|psi-mi:MALSU1(display_short)|uniprotkb:C7orf30(gene name synonym)	psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339741|imex:IM-11696-719	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612455.1|ensembl:ENSG00000156928(gene)|ensembl:ENST00000466681(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0070130"(negative regulation of mitochondrial translation)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|interpro:IPR004394(Iojap-related protein)|interpro:IPR043519|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:7A5H|rcsb pdb:7A5J|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF5|rcsb pdb:7OF7	rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LK1PkohSTYCWy9AlTBzno0IbXE89606	rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606	intact-crc:DCAF1A58C6A0C1B1|rigid:Hg2n31Yc5MRgPT7ex0069vXfZmc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TBC4	uniprotkb:P61081	intact:EBI-717567|uniprotkb:O76088|uniprotkb:Q9NTU3|uniprotkb:A8K027|intact:EBI-2339745|uniprotkb:A6NLB5|ensembl:ENSP00000354340	intact:EBI-1041660|uniprotkb:O76069|uniprotkb:Q8VC50|ensembl:ENSP00000253023	psi-mi:uba3_human(display_long)|uniprotkb:Ubiquitin-like modifier-activating enzyme 3(gene name synonym)|uniprotkb:NEDD8-activating enzyme E1C(gene name synonym)|uniprotkb:Ubiquitin-activating enzyme E1C(gene name synonym)|uniprotkb:UBA3(gene name)|psi-mi:UBA3(display_short)|uniprotkb:UBE1C(gene name synonym)	psi-mi:ubc12_human(display_long)|uniprotkb:UBE2M(gene name)|psi-mi:UBE2M(display_short)|uniprotkb:UBC12(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 M(gene name synonym)|uniprotkb:NEDD8 carrier protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339744|imex:IM-11696-720	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003959.3|refseq:NP_937838.1|ensembl:ENSG00000144744(gene)|ensembl:ENST00000361055(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006508"(proteolysis)|go:"GO:0007113"(endomitotic cell cycle)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019781"(NEDD8 activating enzyme activity)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045116"(protein neddylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR014929(E2 binding)|interpro:IPR023318|interpro:IPR030468|interpro:IPR033127|interpro:IPR035985|mint:Q8TBC4|rcsb pdb:1R4M|rcsb pdb:1R4N|rcsb pdb:1TT5|rcsb pdb:1Y8X|rcsb pdb:1YOV|rcsb pdb:2LQ7|rcsb pdb:2NVU|rcsb pdb:3DBH|rcsb pdb:3DBL|rcsb pdb:3DBR|rcsb pdb:3FN1|rcsb pdb:3GZN|rcsb pdb:5JJM|reactome:R-HSA-5607761|reactome:R-HSA-5676590|reactome:R-HSA-8951664|reactome:R-HSA-983168	refseq:NP_003960.1|ensembl:ENSG00000130725(gene)|ensembl:ENST00000253023(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045116"(protein neddylation)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61081|reactome:R-HSA-8951664|reactome:R-HSA-983168|rcsb pdb:1TT5|rcsb pdb:1Y8X|rcsb pdb:2NVU|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4GAO|rcsb pdb:4P5O|reactome:R-HSA-2173789|reactome:R-HSA-5607761|reactome:R-HSA-5676590|dip:DIP-35679N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:6VcauGap9tDJ780/x06s6QgRr8Y9606	rogid:YfRvkrP+nGQTtjeUsJNDbMm1Nqo9606	intact-crc:C655A9B2FA6CD109|rigid:xQhEy/eUt9OFuSXI7kmjQg0/+QM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62877	uniprotkb:P61081	intact:EBI-398523|uniprotkb:Q8N6Z8|uniprotkb:Q9D1S2|uniprotkb:Q9WUK9|uniprotkb:Q9Y254|uniprotkb:B2RDY1|ensembl:ENSP00000216225	intact:EBI-1041660|uniprotkb:O76069|uniprotkb:Q8VC50|ensembl:ENSP00000253023	psi-mi:rbx1_human(display_long)|uniprotkb:RBX1(gene name)|psi-mi:RBX1(display_short)|uniprotkb:RNF75(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins 1(gene name synonym)|uniprotkb:RING finger protein 75(gene name synonym)|uniprotkb:Protein ZYP(gene name synonym)|uniprotkb:RING-box protein 1(gene name synonym)|uniprotkb:E3 ubiquitin-protein transferase RBX1(gene name synonym)	psi-mi:ubc12_human(display_long)|uniprotkb:UBE2M(gene name)|psi-mi:UBE2M(display_short)|uniprotkb:UBC12(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 M(gene name synonym)|uniprotkb:NEDD8 carrier protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339751|imex:IM-11696-721	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055063.1|dip:DIP-17014N|ensembl:ENSG00000100387(gene)|ensembl:ENST00000216225(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045116"(protein neddylation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|mint:P62877|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:2HYE|rcsb pdb:2LGV|rcsb pdb:3DPL|rcsb pdb:3DQV|rcsb pdb:3RTR|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6TTU|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5S|reactome:R-HSA-110314|reactome:R-HSA-1170546|reactome:R-HSA-1234176|reactome:R-HSA-180585|reactome:R-HSA-195253|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2894862|reactome:R-HSA-4641258|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68949|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168	refseq:NP_003960.1|ensembl:ENSG00000130725(gene)|ensembl:ENST00000253023(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045116"(protein neddylation)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61081|reactome:R-HSA-8951664|reactome:R-HSA-983168|rcsb pdb:1TT5|rcsb pdb:1Y8X|rcsb pdb:2NVU|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4GAO|rcsb pdb:4P5O|reactome:R-HSA-2173789|reactome:R-HSA-5607761|reactome:R-HSA-5676590|dip:DIP-35679N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pSaSNRZo+QudTPXOLUlksOj3smM9606	rogid:YfRvkrP+nGQTtjeUsJNDbMm1Nqo9606	intact-crc:356B7F5E65E72F30|rigid:Nn4369O8VQooo1AyPgvdhtl4Xtc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95376	uniprotkb:O14933	intact:EBI-711158|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9|ensembl:ENSP00000348769|ensembl:ENSP00000403222	intact:EBI-2129974|uniprotkb:A6NDM6|uniprotkb:Q8N5D8|uniprotkb:A8MY53|uniprotkb:Q9UEZ0|ensembl:ENSP00000287156	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym)	psi-mi:ub2l6_human(display_long)|uniprotkb:UBE2L6(gene name)|psi-mi:UBE2L6(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L6(gene name synonym)|uniprotkb:Ubiquitin carrier protein L6(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:Retinoic acid-induced gene B protein(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L6(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339754|imex:IM-11696-722	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|ensembl:ENSG00000177479(gene)|ensembl:ENST00000356401(transcript)|ensembl:ENST00000449376(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|refseq:XP_016861020.1|refseq:XP_016861021.1	refseq:NP_004214.1|refseq:NP_937826.1|ensembl:ENSP00000287156|ensembl:ENST00000340573|ensembl:ENSP00000341980|dip:DIP-41477N|ensembl:ENSG00000156587(gene)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:O14933|rcsb pdb:1WZV|rcsb pdb:1WZW|rcsb pdb:2KJH|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|ensembl:ENST00000287156(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|reactome:R-HSA-936440|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032020"(ISG15-protein conjugation)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	rogid:18K+ReSJfSpKRvnLuED+kPB3beY9606	intact-crc:2D72D51F19534C9C|rigid:IxQonLEzJCGE0POmUpJz61TIxEg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14933	uniprotkb:Q96EQ8	intact:EBI-2129974|uniprotkb:A6NDM6|uniprotkb:Q8N5D8|uniprotkb:A8MY53|uniprotkb:Q9UEZ0|ensembl:ENSP00000287156	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:ub2l6_human(display_long)|uniprotkb:UBE2L6(gene name)|psi-mi:UBE2L6(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L6(gene name synonym)|uniprotkb:Ubiquitin carrier protein L6(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:Retinoic acid-induced gene B protein(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L6(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339757|imex:IM-11696-723	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004214.1|refseq:NP_937826.1|ensembl:ENSP00000287156|ensembl:ENST00000340573|ensembl:ENSP00000341980|dip:DIP-41477N|ensembl:ENSG00000156587(gene)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:O14933|rcsb pdb:1WZV|rcsb pdb:1WZW|rcsb pdb:2KJH|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|ensembl:ENST00000287156(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|reactome:R-HSA-936440|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032020"(ISG15-protein conjugation)	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:18K+ReSJfSpKRvnLuED+kPB3beY9606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	intact-crc:E5981D7E9DFB6440|rigid:iF09gTg942kM+OSUyExkNIs91DM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P68104	uniprotkb:Q969T4	intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym)	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339760|imex:IM-11696-724	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	intact-crc:C6AE90A947E79B88|rigid:SPxLm4Cbz5PpAQek0hnVdDXWkQU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:P50914	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-356746|uniprotkb:Q45RF0|uniprotkb:Q53G20|uniprotkb:Q8TBD5|uniprotkb:Q8WUT0|uniprotkb:Q92579|uniprotkb:Q96GR0|uniprotkb:Q9BSB8|uniprotkb:Q9BW65|uniprotkb:Q9BYF6|ensembl:ENSP00000345156|ensembl:ENSP00000379506	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:rl14_human(display_long)|uniprotkb:RPL14(gene name)|psi-mi:RPL14(display_short)|uniprotkb:CAG-ISL 7(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL14(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339763|imex:IM-11696-725	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_001030168.1|refseq:NP_003964.3|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002784(Ribosomal protein L14)|interpro:IPR008991(Translation protein SH3-like)|ensembl:ENSG00000188846(gene)|ensembl:ENST00000338970(transcript)|ensembl:ENST00000396203(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041985|mint:P50914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|interpro:IPR039660|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y2L	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:AjaguD5hgHtcBbJq5QfuG6XdTcE9606	intact-crc:4209BA9A08FDD3E5|rigid:NcDJa75daVkNYBSjiPfwM4Y1OLI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:Q9UII4	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-2339540|uniprotkb:B2RTQ1|uniprotkb:Q69G20|intact:EBI-28975860|ensembl:ENSP00000264350	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:herc5_human(display_long)|uniprotkb:HERC5(gene name)|psi-mi:HERC5(display_short)|uniprotkb:CEB1(gene name synonym)|uniprotkb:CEBP1(gene name synonym)|uniprotkb:HECT domain and RCC1-like domain-containing protein 5(gene name synonym)|uniprotkb:Cyclin-E-binding protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339769|imex:IM-11696-727	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	ensembl:ENSP00000264350|refseq:NP_057407.2|dip:DIP-44200N|ensembl:ENSG00000138646(gene)|ensembl:ENST00000264350(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000569(HECT)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR035983|mint:Q9UII4|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-936440|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:IGuce5qcdMB8PC5u6b6A57FODKY9606	intact-crc:3ACABB1E9156951D|rigid:WIs0VHVG7LLCroh98C8kXQBuhwg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14157	uniprotkb:Q969T4	intact:EBI-347762|uniprotkb:Q5VU75|uniprotkb:Q5VU76|uniprotkb:Q9BTU3|uniprotkb:Q9UGL2|uniprotkb:Q9UGL3|uniprotkb:Q9UGL5|uniprotkb:B4E0U8|uniprotkb:Q9UGL4|ensembl:ENSP00000355343|ensembl:ENSP00000389445	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	psi-mi:ubp2l_human(display_long)|uniprotkb:UBAP2L(gene name)|psi-mi:UBAP2L(display_short)|uniprotkb:Protein NICE-4(gene name synonym)|uniprotkb:KIAA0144(gene name synonym)|uniprotkb:NICE4(gene name synonym)	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339766|imex:IM-11696-726	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508518.1|refseq:NP_001120792.1|refseq:NP_055662.3|refseq:NP_001274744.1|refseq:NP_001274745.1|refseq:XP_005245731.1|refseq:XP_016858467.1|refseq:XP_016858468.1|refseq:XP_016858475.1|refseq:XP_016858476.1|refseq:XP_016858478.1|refseq:XP_016858479.1|ensembl:ENSG00000143569(gene)|ensembl:ENST00000361546(transcript)|ensembl:ENST00000428931(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031519"(PcG protein complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|mint:Q14157	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:4iKY4hJOHGSyOOt8zfPhkeyth6Q9606	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	intact-crc:09530BCB2C8F0B65|rigid:M2RG2CDvW7FMJEsYxl29PTuKh+w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:O95071	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-358329|uniprotkb:O94970|uniprotkb:Q9NPL3|ensembl:ENSP00000429084|uniprotkb:B2RP24|intact:EBI-10967451|uniprotkb:J3KMW7	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:ubr5_human(display_long)|uniprotkb:UBR5(gene name)|psi-mi:UBR5(display_short)|uniprotkb:HYD(gene name synonym)|uniprotkb:KIAA0896(gene name synonym)|uniprotkb:EDD(gene name synonym)|uniprotkb:EDD1(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:Progestin-induced protein(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339772|imex:IM-11696-728	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_001269802.1|ensembl:ENST00000520539(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|ensembl:ENSG00000104517(gene)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|mint:O95071|rcsb pdb:1I2T|rcsb pdb:2QHO|refseq:NP_056986.2|rcsb pdb:3PT3|dip:DIP-32930N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:5yiXAYJbV4iA8d3btwaVfL7vaik9606	intact-crc:0E38104F591D828D|rigid:xGi7XbXTsp0LcXeisyJdsY2gSrk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:O95777	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-347779|ensembl:ENSP00000249299	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:lsm8_human(display_long)|uniprotkb:LSM8(gene name)|psi-mi:LSM8(display_short)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339775|imex:IM-11696-729	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_057284.1|dip:DIP-31195N|ensembl:ENSG00000128534(gene)|ensembl:ENST00000249299(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034103|interpro:IPR044642|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-72163	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:Kyf8IAEIkbe1s2NnqxqGA1o6BbU9606	intact-crc:B659D5C163AB5800|rigid:VVyeetjzndUP4ktQxaEJ1BW7sgQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VTB9	uniprotkb:Q969T4	intact:EBI-949963|ensembl:ENSP00000347548|ensembl:ENSP00000354872|ensembl:ENSP00000361321|uniprotkb:B3KPJ3|uniprotkb:Q4KMX2|uniprotkb:Q9NVP6|uniprotkb:B4DLZ9|uniprotkb:E9PCS1	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	psi-mi:rn220_human(display_long)|uniprotkb:C1orf164(gene name synonym)|uniprotkb:RNF220(gene name)|psi-mi:RNF220(display_short)|uniprotkb:RING finger protein 220(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF220(gene name synonym)	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339789|imex:IM-11696-731	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060620.2|ensembl:ENSG00000187147(gene)|ensembl:ENST00000355387(transcript)|ensembl:ENST00000361799(transcript)|ensembl:ENST00000372247(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031824|interpro:IPR040178|reactome:R-HSA-983168|refseq:NP_001306885.1|refseq:NP_001306886.1|refseq:XP_016857112.1|refseq:XP_016857113.1|refseq:XP_016857114.1	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:++tO9LPa3Hh0vhx5A1fIyv+5Djc9606	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	intact-crc:BC06C4288CEA1778|rigid:jkqKCOkGQYtk8k+6vU9nANRNCkQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TEP8	uniprotkb:Q969T4	intact:EBI-2339778|uniprotkb:Q9H0F4|uniprotkb:Q8WYT8|uniprotkb:Q9NW27|uniprotkb:A0A060A9S4|intact:EBI-11329707|uniprotkb:B7ZMF0|uniprotkb:E9PF99|intact:EBI-10984660|ensembl:ENSP00000427550	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	psi-mi:ce192_human(display_long)|uniprotkb:CEP192(gene name)|psi-mi:CEP192(display_short)|uniprotkb:KIAA1569(gene name synonym)|uniprotkb:PP8407(orf name)	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339786|imex:IM-11696-730	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115518.3|dip:DIP-52779N|ensembl:ENSG00000101639(gene)|ensembl:ENST00000506447(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007099"(centriole replication)|go:"GO:0009617"(response to bacterium)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090222"(centrosome-templated microtubule nucleation)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR039103|rcsb pdb:4N7Z|rcsb pdb:6FVI|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2018/07/23	rogid:XXxzXD9dfRTtgx/tKR0VhGAlPWc9606	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	intact-crc:488ECB4736862A2D|rigid:W6YVuKVy0Ds51LtxhHPxhP78+B4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	intact:EBI-2342206	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	-	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:bu622909_hum_protein(display_short)|psi-mi:EBI-2342206(display_long)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339801|imex:IM-11696-580	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	genbank_nucl_gi:622909(primary-reference)	psi-mi:"MI:0469"(intact)	-	no-uniprot-update:An amino acid sequence which is not represented in UniProt	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	-	intact-crc:BE518AA1862A15E5	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:Q8NF67	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-2339795	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:a2012_human(display_long)|uniprotkb:ANKRD20A12P(gene name)|psi-mi:ANKRD20A12P(display_short)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339798|imex:IM-11696-733	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	interpro:IPR039497	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:pbkYxUq9I5R4Fbswp3UxLD/wwOg9606	intact-crc:2B9DF47462919FD3|rigid:WvlEbDAIqQEHnM5tHhnAdhjaFDc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5I2	uniprotkb:Q969T4	intact:EBI-2339564|ensembl:ENSP00000360475	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	psi-mi:arrd1_human(display_long)|uniprotkb:Alpha-arrestin 1(gene name synonym)|uniprotkb:ARRDC1(gene name)|psi-mi:ARRDC1(display_short)	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339792|imex:IM-11696-732	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689498.1|ensembl:ENSP00000360475|ensembl:ENSG00000197070(gene)|ensembl:ENST00000371421(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006858"(extracellular transport)|go:"GO:0015031"(protein transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140112"(extracellular vesicle biogenesis)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Q776M1DBnxGDHoHAqS666mel0hM9606	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	intact-crc:876965DFCC2745BC|rigid:M/11uKV8TSpjckiZg1gLoTxOhlM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96S59	uniprotkb:O00762	intact:EBI-636085|uniprotkb:A0PJA2|uniprotkb:O94764|uniprotkb:Q6P3T7|uniprotkb:Q7LBR2|uniprotkb:Q7Z7F9|ensembl:ENSP00000011619|uniprotkb:B2R8E1	intact:EBI-719691|uniprotkb:A6NP33|uniprotkb:E1P5N7|uniprotkb:G3XAB7|ensembl:ENSP00000348838	psi-mi:ranb9_human(display_long)|uniprotkb:RanBP7(gene name synonym)|uniprotkb:Ran-binding protein M(gene name synonym)|uniprotkb:BPM90(gene name synonym)|uniprotkb:BPM-L(gene name synonym)|uniprotkb:RANBP9(gene name)|psi-mi:RANBP9(display_short)|uniprotkb:RANBPM(gene name synonym)	psi-mi:ube2c_human(display_long)|uniprotkb:Ubiquitin-protein ligase C(gene name synonym)|uniprotkb:Ubiquitin carrier protein C(gene name synonym)|uniprotkb:UbcH10(gene name synonym)|uniprotkb:UBE2C(gene name)|psi-mi:UBE2C(display_short)|uniprotkb:UBCH10(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme C"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme C(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339803|imex:IM-11696-734	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005484.2|ensembl:ENSG00000010017(gene)|ensembl:ENST00000011619(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|interpro:IPR035782|interpro:IPR043136|mint:Q96S59|rcsb pdb:5JI7|rcsb pdb:5JI9|rcsb pdb:5JIU|rcsb pdb:7NSC|reactome:R-HSA-373760|reactome:R-HSA-5673001|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|reactome:R-HSA-8851805|refseq:XP_006715008.1	refseq:NP_008950.1|refseq:NP_861515.1|refseq:NP_861516.1|refseq:NP_861517.1|ensembl:ENSG00000175063(gene)|ensembl:ENST00000356455(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1I7K|rcsb pdb:4YII|rcsb pdb:5A31|rcsb pdb:5KHR|rcsb pdb:5L9U|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:NP_001268670.1|refseq:NP_001268671.1|dip:DIP-52725N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:7jybZidQAgnkobKmGJhZ9xsEeH09606	rogid:sJ/R8NL1aVdljasuqKJbVg8gyTM9606	intact-crc:6D78185EE4972D3B|rigid:O1Pe528r3yD7WzAiRv2YUWnNjgE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00762	uniprotkb:Q3KNV8	intact:EBI-719691|uniprotkb:A6NP33|uniprotkb:E1P5N7|uniprotkb:G3XAB7|ensembl:ENSP00000348838	intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489	psi-mi:ube2c_human(display_long)|uniprotkb:Ubiquitin-protein ligase C(gene name synonym)|uniprotkb:Ubiquitin carrier protein C(gene name synonym)|uniprotkb:UbcH10(gene name synonym)|uniprotkb:UBE2C(gene name)|psi-mi:UBE2C(display_short)|uniprotkb:UBCH10(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme C"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme C(gene name synonym)	psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339806|imex:IM-11696-735	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008950.1|refseq:NP_861515.1|refseq:NP_861516.1|refseq:NP_861517.1|ensembl:ENSG00000175063(gene)|ensembl:ENST00000356455(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1I7K|rcsb pdb:4YII|rcsb pdb:5A31|rcsb pdb:5KHR|rcsb pdb:5L9U|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:NP_001268670.1|refseq:NP_001268671.1|dip:DIP-52725N	refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:sJ/R8NL1aVdljasuqKJbVg8gyTM9606	rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606	intact-crc:AAF27DF845C4E29D|rigid:2gdptDc4+Ber7nFu+wW2WHAtTFI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16763	uniprotkb:O76095	intact:EBI-2339823|uniprotkb:Q9BTC1|ensembl:ENSP00000264552	intact:EBI-2339818|uniprotkb:Q6IB19|uniprotkb:Q9P0Q4|uniprotkb:O95442|ensembl:ENSP00000271843	psi-mi:ube2s_human(display_long)|uniprotkb:UBE2S(gene name)|psi-mi:UBE2S(display_short)|uniprotkb:E2EPF(gene name synonym)|uniprotkb:Ubiquitin-protein ligase S(gene name synonym)|uniprotkb:Ubiquitin carrier protein S(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-24 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-EPF5(gene name synonym)|uniprotkb:OK/SW-cl.73(orf name)|uniprotkb:E2-EPF(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme S(gene name synonym)	psi-mi:jtb_human(display_long)|uniprotkb:JTB(gene name)|psi-mi:JTB(display_short)|uniprotkb:Jumping translocation breakpoint protein(gene name synonym)|uniprotkb:Prostate androgen-regulated protein(gene name synonym)|uniprotkb:HSPC222(orf name)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339817|imex:IM-11696-737	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055316.2|dip:DIP-52784N|ensembl:ENSG00000108106(gene)|ensembl:ENST00000264552(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051301"(cell division)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1ZDN|rcsb pdb:5BNB|rcsb pdb:5L9T|rcsb pdb:6QH3|rcsb pdb:6QHK|rcsb pdb:6S96|rcsb pdb:6S98|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-9687136|reactome:R-HSA-983168	refseq:NP_006685.1|ensembl:ENSG00000143543|ensembl:ENSG00000143543(gene)|ensembl:ENST00000271843(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0045860"(positive regulation of protein kinase activity)|interpro:IPR008657(Jumping translocation breakpoint)|rcsb pdb:2KJX	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:PiLqBXIHRM8f6hlUXU6PkI3xNtM9606	rogid:+kbmONvsTzUE4lzJz9nQFBInol49606	intact-crc:65E3FFC64574E836|rigid:gPeRXY/FvcRF6wSqGqfLuf4BCLo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00762	uniprotkb:Q99848	intact:EBI-719691|uniprotkb:A6NP33|uniprotkb:E1P5N7|uniprotkb:G3XAB7|ensembl:ENSP00000348838	intact:EBI-1048111|uniprotkb:Q96A66|ensembl:ENSP00000236051	psi-mi:ube2c_human(display_long)|uniprotkb:Ubiquitin-protein ligase C(gene name synonym)|uniprotkb:Ubiquitin carrier protein C(gene name synonym)|uniprotkb:UbcH10(gene name synonym)|uniprotkb:UBE2C(gene name)|psi-mi:UBE2C(display_short)|uniprotkb:UBCH10(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme C"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme C(gene name synonym)	psi-mi:ebp2_human(display_long)|uniprotkb:EBNA1-binding protein 2(gene name synonym)|uniprotkb:Nucleolar protein p40(gene name synonym)|uniprotkb:EBNA1BP2(gene name)|psi-mi:EBNA1BP2(display_short)|uniprotkb:EBP2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339814|imex:IM-11696-736	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008950.1|refseq:NP_861515.1|refseq:NP_861516.1|refseq:NP_861517.1|ensembl:ENSG00000175063(gene)|ensembl:ENST00000356455(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1I7K|rcsb pdb:4YII|rcsb pdb:5A31|rcsb pdb:5KHR|rcsb pdb:5L9U|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:NP_001268670.1|refseq:NP_001268671.1|dip:DIP-52725N	refseq:NP_001153408.1|refseq:NP_006815.2|ensembl:ENSG00000117395(gene)|ensembl:ENST00000236051(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR008610(Eukaryotic rRNA processing)|mint:Q99848|reactome:R-HSA-6791226	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:sJ/R8NL1aVdljasuqKJbVg8gyTM9606	rogid:lUFbxBko/pJHiNq8uuefmK3Xqp89606	intact-crc:83D8D8ABEBB7AD90|rigid:dTNpgCB1CGHdrYMCy341QYpf0rw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y5L0	uniprotkb:Q16763	intact:EBI-1042571|uniprotkb:A4D1K9|uniprotkb:Q6NUM1|uniprotkb:Q96G71|uniprotkb:Q96GU9|uniprotkb:Q9Y3R2|uniprotkb:C9IZM0|ensembl:ENSP00000265388	intact:EBI-2339823|uniprotkb:Q9BTC1|ensembl:ENSP00000264552	psi-mi:tnpo3_human(display_long)|uniprotkb:TNPO3(gene name)|psi-mi:TNPO3(display_short)|uniprotkb:IPO12(gene name synonym)|uniprotkb:Transportin-SR(gene name synonym)|uniprotkb:Importin-12(gene name synonym)	psi-mi:ube2s_human(display_long)|uniprotkb:UBE2S(gene name)|psi-mi:UBE2S(display_short)|uniprotkb:E2EPF(gene name synonym)|uniprotkb:Ubiquitin-protein ligase S(gene name synonym)|uniprotkb:Ubiquitin carrier protein S(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-24 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-EPF5(gene name synonym)|uniprotkb:OK/SW-cl.73(orf name)|uniprotkb:E2-EPF(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme S(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339830|imex:IM-11696-738	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177957.2|refseq:NP_036602.1|ensembl:ENSG00000064419(gene)|ensembl:ENST00000265388(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y5L0|rcsb pdb:4C0O|rcsb pdb:4C0P|rcsb pdb:4C0Q|rcsb pdb:4OL0|rcsb pdb:6GX9	refseq:NP_055316.2|dip:DIP-52784N|ensembl:ENSG00000108106(gene)|ensembl:ENST00000264552(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051301"(cell division)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1ZDN|rcsb pdb:5BNB|rcsb pdb:5L9T|rcsb pdb:6QH3|rcsb pdb:6QHK|rcsb pdb:6S96|rcsb pdb:6S98|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-9687136|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Xvd5fZ4wlMc6R6w2wL+JhIOOuIE9606	rogid:PiLqBXIHRM8f6hlUXU6PkI3xNtM9606	intact-crc:35461D97B4255095|rigid:moYISrVF6b3/ImtI3CTPwjYiL/8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NPD8	uniprotkb:O95376	intact:EBI-2130165|uniprotkb:Q2TU36|ensembl:ENSP00000494957	intact:EBI-711158|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9|ensembl:ENSP00000348769|ensembl:ENSP00000403222	psi-mi:ube2t_human(display_long)|uniprotkb:UBE2T(gene name)|psi-mi:UBE2T(display_short)|uniprotkb:Ubiquitin-protein ligase T(gene name synonym)|uniprotkb:Ubiquitin carrier protein T(gene name synonym)|uniprotkb:HSPC150(orf name)|uniprotkb:Cell proliferation-inducing gene 50 protein(gene name synonym)|uniprotkb:PIG50(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme T(gene name synonym)	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339833|imex:IM-11696-739	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054895.1|refseq:NP_001297255.1|dip:DIP-52740N|ensembl:ENSG00000077152(gene)|ensembl:ENST00000646651(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YH2|rcsb pdb:4CCG|rcsb pdb:5NGZ|rcsb pdb:5OJJ|rcsb pdb:6R75|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|reactome:R-HSA-8866652	refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|ensembl:ENSG00000177479(gene)|ensembl:ENST00000356401(transcript)|ensembl:ENST00000449376(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|refseq:XP_016861020.1|refseq:XP_016861021.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hKFqKCWzIhcGshB1ut+mTTSwxbQ9606	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	intact-crc:E133B15D6E651422|rigid:akMzwl5BR9JEhDm1I+r1PNVebVQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22314	uniprotkb:Q9Y385	intact:EBI-709688|uniprotkb:Q96E13|uniprotkb:Q5JRR8|ensembl:ENSP00000338413|ensembl:ENSP00000366568	intact:EBI-988826|uniprotkb:Q5W0N4|uniprotkb:Q9BZ32|uniprotkb:Q9NQL3|uniprotkb:Q9NY66|uniprotkb:Q9P011|uniprotkb:Q9P0S0|uniprotkb:Q9UF10|ensembl:ENSP00000451261|uniprotkb:A8K3F9|uniprotkb:Q53F25	psi-mi:uba1_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1(gene name synonym)|uniprotkb:Protein A1S9(gene name synonym)|uniprotkb:UBA1(gene name)|psi-mi:UBA1(display_short)|uniprotkb:A1S9T(gene name synonym)|uniprotkb:UBE1(gene name synonym)	psi-mi:ub2j1_human(display_long)|uniprotkb:Non-canonical ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:Yeast ubiquitin-conjugating enzyme UBC6 homolog E(gene name synonym)|uniprotkb:UBE2J1(gene name)|psi-mi:UBE2J1(display_short)|uniprotkb:NCUBE1(gene name synonym)|uniprotkb:CGI-76(orf name)|uniprotkb:HSPC153(orf name)|uniprotkb:HSPC205(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme J1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339836|imex:IM-11696-740	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003325.2|refseq:NP_695012.1|refseq:XP_016885269.1|refseq:XP_016885270.1|dip:DIP-33686N|ensembl:ENSG00000130985(gene)|ensembl:ENST00000335972(transcript)|ensembl:ENST00000377351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|mint:P22314|rcsb pdb:4P22|rcsb pdb:6DC6|reactome:R-HSA-8866652|reactome:R-HSA-983168	go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|reactome:R-HSA-983168|ensembl:ENSG00000198833(gene)|ensembl:ENST00000435041(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007286"(spermatid development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_057105.2|dip:DIP-45598N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:q+vEeA0XLST0Zz173bmEt0dNbDE9606	rogid:nc3+V3Qxy1ZDhTWgTPLakJukxPM9606	intact-crc:28EEFFF14DC5A066|rigid:2Ulc3eOcghzfTvuSLSz7KNOX5Lc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:O94788	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-2339839|uniprotkb:H0YM00|uniprotkb:Q9UFY0|uniprotkb:Q8NHQ4|uniprotkb:B3KY52|uniprotkb:Q2PJS6|uniprotkb:Q9UBR8|uniprotkb:B4DZR2|uniprotkb:F5H2Y9|ensembl:ENSP00000249750	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:al1a2_human(display_long)|uniprotkb:ALDH1A2(gene name)|psi-mi:ALDH1A2(display_short)|uniprotkb:RALDH2(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 1 member A2(gene name synonym)|uniprotkb:Retinaldehyde-specific dehydrogenase type 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339848|imex:IM-11696-741	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_001193826.1|refseq:NP_003879.2|refseq:NP_733797.1|refseq:NP_733798.1|go:"GO:0005829"(cytosol)|go:"GO:0006776"(vitamin A metabolic process)|go:"GO:0007494"(midgut development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009855"(determination of bilateral symmetry)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0016918"(retinal binding)|go:"GO:0021915"(neural tube development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030902"(hindbrain development)|go:"GO:0031016"(pancreas development)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0032355"(response to estradiol)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035799"(ureter maturation)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042573"(retinoic acid metabolic process)|go:"GO:0042574"(retinal metabolic process)|go:"GO:0042904"(9-cis-retinoic acid biosynthetic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060324"(face development)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0090242"(retinoic acid receptor signaling pathway involved in somitogenesis)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|rcsb pdb:4X2Q|rcsb pdb:6ALJ|ensembl:ENSG00000128918(gene)|ensembl:ENST00000249750(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001758"(retinal dehydrogenase activity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0001936"(regulation of endothelial cell proliferation)|go:"GO:0002138"(retinoic acid biosynthetic process)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0004028"(3-chloroallyl aldehyde dehydrogenase activity)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|rcsb pdb:6B5G|rcsb pdb:6B5H|rcsb pdb:6B5I|reactome:R-HSA-5365859|go:"GO:0005737"(cytoplasm)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:F1dgyyVoKLrTfy3axgnZZine+CA9606	intact-crc:074DB3CC9CC6B29E|rigid:bzGFwDwKNEfntECGE6kEoSRoB34	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q86Y13	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339851|imex:IM-11696-742	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:70E362121BE3AC52|rigid:5Rhq0N3DDq0S4EQvjeCa6AS083U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86X55	uniprotkb:Q9Y2X8	intact:EBI-2339854|uniprotkb:A6NN38|ensembl:ENSP00000325690	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:carm1_human(display_long)|uniprotkb:CARM1(gene name)|psi-mi:CARM1(display_short)|uniprotkb:PRMT4(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 4(gene name synonym)|uniprotkb:Coactivator-associated arginine methyltransferase 1(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339858|imex:IM-11696-743	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_954592.1|refseq:XP_005259765.1|dip:DIP-44071N|ensembl:ENSG00000142453(gene)|ensembl:ENST00000327064(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0034971"(histone H3-R17 methylation)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0035642"("histone methyltransferase activity (H3-R17 specific)")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:1902415"(regulation of mRNA binding)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020989|interpro:IPR025799|interpro:IPR029063|mint:Q86X55|rcsb pdb:2Y1W|rcsb pdb:2Y1X|rcsb pdb:4IKP|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5DX1|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5DXJ|rcsb pdb:5U4X|rcsb pdb:6ARJ|rcsb pdb:6ARV|rcsb pdb:6D2L|rcsb pdb:6DVR|rcsb pdb:6IZQ|rcsb pdb:6S70|rcsb pdb:6S71|rcsb pdb:6S74|rcsb pdb:6S77|rcsb pdb:6S79|rcsb pdb:6S7A|rcsb pdb:6S7B|rcsb pdb:6S7C|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-6804114|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|go:"GO:0051591"(response to cAMP)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1x1bUjqcA/ZpmrSsSM545ReYH2A9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:F5C129A7DC38C005|rigid:aL2mEzhY64qcg6DA90tpFB/JCC0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q96EP1	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-718923|uniprotkb:A6NEN5|uniprotkb:Q96SL3|uniprotkb:Q9NRT4|uniprotkb:Q9NT32|uniprotkb:Q9NVD5|uniprotkb:B4DZ77|uniprotkb:B4E2L6|ensembl:ENSP00000392395	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:chfr_human(display_long)|uniprotkb:Checkpoint with forkhead and RING finger domains protein(gene name synonym)|uniprotkb:RING finger protein 196(gene name synonym)|uniprotkb:CHFR(gene name)|psi-mi:CHFR(display_short)|uniprotkb:RNF196(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHFR(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339864|imex:IM-11696-745	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_001154816.1|refseq:NP_001154817.1|refseq:NP_001154818.1|refseq:NP_001154819.1|refseq:NP_060693.2|ensembl:ENSG00000072609(gene)|ensembl:ENST00000432561(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR019406|interpro:IPR040909|rcsb pdb:1LGP|rcsb pdb:1LGQ|rcsb pdb:2XOC|rcsb pdb:2XOY|rcsb pdb:2XOZ|rcsb pdb:2XP0|dip:DIP-40098N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid://FU72n6rmuPAu+Fjm377S4nEjw9606	intact-crc:3D15B8B780FFDDE6|rigid:mWWrdCjcBQGk6xS9PU95xx7Andw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q9Y508	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-723587|uniprotkb:Q6N0B0|uniprotkb:B2RDQ9|uniprotkb:B4DWY5|uniprotkb:E1P627|ensembl:ENSP00000244061	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:rn114_human(display_long)|uniprotkb:Zinc finger protein 313(gene name synonym)|uniprotkb:RNF114(gene name)|psi-mi:RNF114(display_short)|uniprotkb:ZNF313(gene name synonym)|uniprotkb:ZNF228(gene name synonym)|uniprotkb:Zinc finger protein 228(gene name synonym)|uniprotkb:RING finger protein 114(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF114(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339867|imex:IM-11696-746	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_061153.1|ensembl:ENSG00000124226(gene)|ensembl:ENST00000244061(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR034734|interpro:IPR042716|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:R1fX8xaGuIhy/M6cLzPeyfJBf649606	intact-crc:DF585E7C26A184AD|rigid:KK+IxL4KQorrVdiJ6b84s1Pp9DA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BV68	uniprotkb:Q9Y2X8	intact:EBI-357322|ensembl:ENSP00000292363|uniprotkb:Q9NWX1|intact:EBI-11064977	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:rn126_human(display_long)|uniprotkb:RNF126(gene name)|psi-mi:RNF126(display_short)|uniprotkb:RING finger protein 126(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339861|imex:IM-11696-744	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000070423(gene)|ensembl:ENST00000292363(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR039525|interpro:IPR039571|interpro:IPR039572|rcsb pdb:2N9O|rcsb pdb:2N9P|reactome:R-HSA-983168|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|refseq:NP_919442.1	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2019/01/23	rogid:4Z4AJGHJgoIUp9zhtfWcFBF1Fxw9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:E04C9DF51FB0B295|rigid:5jyW+P/wljg6k9hVkR/yNbC2cJs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q9HAC8	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-745871|uniprotkb:Q53HI3|uniprotkb:D3DR57|ensembl:ENSP00000359698	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:ubtd1_human(display_long)|uniprotkb:UBTD1(gene name)|psi-mi:UBTD1(display_short)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339876|imex:IM-11696-749	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_079230.1|ensembl:ENSG00000165886(gene)|ensembl:ENST00000370664(transcript)|interpro:IPR000626(Ubiquitin)|interpro:IPR019956|interpro:IPR029071|interpro:IPR032752|interpro:IPR038169|interpro:IPR039869	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:P3QDDjw2RjE5kaJgtb5z6/Kmroc9606	intact-crc:FBCD823483DAB285|rigid:uMOmEbIPvWDVa8ASRJQP45l5Vjk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q9P2E3	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-308745|uniprotkb:Q9BQM7|uniprotkb:Q9BQM8|uniprotkb:Q9H8C1|uniprotkb:Q9H9S2|uniprotkb:Q9NUM1|uniprotkb:Q9NWW1|ensembl:ENSP00000360817|ensembl:ENSP00000379412	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:znfx1_human(display_long)|uniprotkb:ZNFX1(gene name)|psi-mi:ZNFX1(display_short)|uniprotkb:KIAA1404(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339870|imex:IM-11696-747	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_066363.1|ensembl:ENSG00000124201(gene)|ensembl:ENST00000371752(transcript)|ensembl:ENST00000396105(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0031380"(nuclear RNA-directed RNA polymerase complex)|interpro:IPR000967(Zinc finger, NF-X1-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|mint:Q9P2E3|refseq:XP_006723899.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:2vNUbYE3//YGh0eabKbzldLESF49606	intact-crc:04B3E6C9D299DD42|rigid:XG/ooMl+tvPLrGpv33W0VVVkPE4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q9BY78	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-2129375|uniprotkb:Q542Y8|intact:EBI-2339452|intact:EBI-28972797|ensembl:ENSP00000312439	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:rnf26_human(display_long)|uniprotkb:RNF26(gene name)|psi-mi:RNF26(display_short)|uniprotkb:RING finger protein 26(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339873|imex:IM-11696-748	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	ensembl:ENSP00000312439|refseq:NP_114404.1|ensembl:ENSG00000173456(gene)|ensembl:ENST00000311413(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007032"(endosome organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040089	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:R0awMKLLQSLU9zjVe/ivOWeYjnE9606	intact-crc:65AD5AE9AD0669F8|rigid:FdOlf2KnhBRDf1DZWSQSve7fk+o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q86UW9	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-740376|uniprotkb:Q96H69|uniprotkb:Q9H890|uniprotkb:Q9P200|uniprotkb:Q6XM88|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|uniprotkb:Q6XM87|intact:EBI-10192429|uniprotkb:Q4ZH49	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:dtx2_human(display_long)|uniprotkb:RING finger protein 58(gene name synonym)|uniprotkb:DTX2(gene name)|psi-mi:DTX2(display_short)|uniprotkb:KIAA1528(gene name synonym)|uniprotkb:RNF58(gene name synonym)|uniprotkb:Protein deltex-2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339882|imex:IM-11696-751	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_001096064.1|refseq:NP_001096065.1|refseq:NP_001096066.1|refseq:NP_065943.2|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|ensembl:ENST00000446820|ensembl:ENSP00000392545|ensembl:ENSG00000091073(gene)|ensembl:ENST00000324432(transcript)|ensembl:ENST00000413936(transcript)|ensembl:ENST00000430490(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004170(WWE)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018123|interpro:IPR018957|interpro:IPR037197|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|mint:Q86UW9|rcsb pdb:6IR0|rcsb pdb:6Y22|rcsb pdb:6Y2X|rcsb pdb:6Y3J|reactome:R-HSA-2122948|refseq:XP_011514074.1|refseq:XP_011514075.1|refseq:XP_011514076.1|refseq:XP_011514077.1|refseq:XP_005250188.1|refseq:XP_005250189.1|refseq:XP_016867212.1|refseq:XP_016867213.1|refseq:XP_016867214.1|refseq:XP_016867215.1|refseq:XP_016867216.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:ugnjqAbG6Ekyc8MGugCnjc9zVaI9606	intact-crc:7CBF14508C8E18BC|rigid:CaG4rfgp7WuN5jVgT1MmLNCgoEE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q8ND25	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339879|imex:IM-11696-750	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	intact-crc:5598279D638D76DF|rigid:mH4bJ7EzaYlJ45XsaG8i4IFaz/k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62841	uniprotkb:Q96B02	intact:EBI-372635|uniprotkb:Q3KRA1|uniprotkb:P11174|uniprotkb:A5D8V9|uniprotkb:Q9UDC2|ensembl:ENSP00000467466	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:rs15_human(display_long)|uniprotkb:RIG protein(gene name synonym)|uniprotkb:RPS15(gene name)|psi-mi:RPS15(display_short)|uniprotkb:RIG(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS19(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339885|imex:IM-11696-752	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009.1|mint:P62841|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|ensembl:ENSG00000115268(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|ensembl:ENST00000592588(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0097421"(liver regeneration)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|interpro:IPR020934|go:"GO:0003735"(structural constituent of ribosome)|interpro:IPR023575|rcsb pdb:6ZVH|rcsb pdb:6ZMT|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6ZMW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:lJJOew1txuTwFlhKu4Z+AkPS5H09606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:A0E1523670C409A4|rigid:sAVbJTKY1KltUlsfw9oAAZu0J1s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62266	uniprotkb:Q96B02	intact:EBI-353072|ensembl:ENSP00000296674|ensembl:ENSP00000498621|uniprotkb:P39028|uniprotkb:Q6IB08	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:rs23_human(display_long)|uniprotkb:RPS23(gene name)|psi-mi:RPS23(display_short)|uniprotkb:Small ribosomal subunit protein uS12(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339888|imex:IM-11696-753	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000186468(gene)|ensembl:ENST00000296674(transcript)|ensembl:ENST00000651545(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0034063"(stress granule assembly)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:1990145"(maintenance of translational fidelity)|interpro:IPR005680(Ribosomal protein S23, eukaryotic/archaeal)|interpro:IPR006032(Ribosomal protein S12/S23)|rcsb pdb:5T2C|rcsb pdb:5VYC|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|mint:P62266|rcsb pdb:6G4W|rcsb pdb:4CXG|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:4CXH|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:4UG0|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|refseq:NP_001016.1	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:MWZPvSL/G45ocaxA5AXKCkDQxNU9606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:E8DA3DD47772D379|rigid:HFgYAjTyQJgy5y1upBIUUzHn6A4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q86Y13	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339891|imex:IM-11696-754	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:6EDEB5A336DB6019|rigid:HYtha5mNnj5jEqIU3YBVka/4hgA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q9NZS9	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-2130199|uniprotkb:A8K4Z9|uniprotkb:D3DUG8|uniprotkb:B4DUT0|ensembl:ENSP00000261658|ensembl:ENSP00000478190	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:bfar_human(display_long)|uniprotkb:BFAR(gene name)|psi-mi:BFAR(display_short)|uniprotkb:BAR(gene name synonym)|uniprotkb:RNF47(gene name synonym)|uniprotkb:RING finger protein 47(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339894|imex:IM-11696-755	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_057645.1|refseq:XP_005255407.1|ensembl:ENSG00000103429(gene)|ensembl:ENSG00000275618(gene)|ensembl:ENST00000261658(transcript)|ensembl:ENST00000619034(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017907	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:XDPFsRmdbch1NXffLOcE0lVrtRo9606	intact-crc:8300DD17DBD8C663|rigid:akQk/8F0zYi5hkffY6Pe6Sp/JGc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NW38	uniprotkb:Q96B02	intact:EBI-2339898|uniprotkb:Q6GU60|ensembl:ENSP00000233741	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:fancl_human(display_long)|uniprotkb:FANCL(gene name)|psi-mi:FANCL(display_short)|uniprotkb:PHF9(gene name synonym)|uniprotkb:Fanconi anemia group L protein(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 43 kDa(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase FANCL(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339897|imex:IM-11696-756	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001108108.1|refseq:NP_060532.2|dip:DIP-43975N|ensembl:ENSG00000115392(gene)|ensembl:ENST00000233741(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007276"(gamete generation)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR019162|interpro:IPR026848|interpro:IPR026850|interpro:IPR043003|interpro:IPR043898|interpro:IPR044037|mint:Q9NW38|rcsb pdb:3ZQS|rcsb pdb:4CCG|rcsb pdb:7KZP|rcsb pdb:7KZQ|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:/zKdeyrga9pwhTbVoZsUFbMBj5g9606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:D4BC7C889715471F|rigid:B4zHjP1x84V3nMlQs0kpDGAG1G4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q5VTB9	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-949963|ensembl:ENSP00000347548|ensembl:ENSP00000354872|ensembl:ENSP00000361321|uniprotkb:B3KPJ3|uniprotkb:Q4KMX2|uniprotkb:Q9NVP6|uniprotkb:B4DLZ9|uniprotkb:E9PCS1	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:rn220_human(display_long)|uniprotkb:C1orf164(gene name synonym)|uniprotkb:RNF220(gene name)|psi-mi:RNF220(display_short)|uniprotkb:RING finger protein 220(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF220(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339905|imex:IM-11696-757	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_060620.2|ensembl:ENSG00000187147(gene)|ensembl:ENST00000355387(transcript)|ensembl:ENST00000361799(transcript)|ensembl:ENST00000372247(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031824|interpro:IPR040178|reactome:R-HSA-983168|refseq:NP_001306885.1|refseq:NP_001306886.1|refseq:XP_016857112.1|refseq:XP_016857113.1|refseq:XP_016857114.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:++tO9LPa3Hh0vhx5A1fIyv+5Djc9606	intact-crc:D842B03A99A38445|rigid:zG+Xgpt31jufGH57x/iMYrNXVWg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q96EP1	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-718923|uniprotkb:A6NEN5|uniprotkb:Q96SL3|uniprotkb:Q9NRT4|uniprotkb:Q9NT32|uniprotkb:Q9NVD5|uniprotkb:B4DZ77|uniprotkb:B4E2L6|ensembl:ENSP00000392395	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:chfr_human(display_long)|uniprotkb:Checkpoint with forkhead and RING finger domains protein(gene name synonym)|uniprotkb:RING finger protein 196(gene name synonym)|uniprotkb:CHFR(gene name)|psi-mi:CHFR(display_short)|uniprotkb:RNF196(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHFR(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339908|imex:IM-11696-758	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_001154816.1|refseq:NP_001154817.1|refseq:NP_001154818.1|refseq:NP_001154819.1|refseq:NP_060693.2|ensembl:ENSG00000072609(gene)|ensembl:ENST00000432561(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR019406|interpro:IPR040909|rcsb pdb:1LGP|rcsb pdb:1LGQ|rcsb pdb:2XOC|rcsb pdb:2XOY|rcsb pdb:2XOZ|rcsb pdb:2XP0|dip:DIP-40098N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid://FU72n6rmuPAu+Fjm377S4nEjw9606	intact-crc:426F5F12AD5A83A6|rigid:fvoa37FeDzXmDKmqnDXisyq+TVo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q5XPI4	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-1057418|uniprotkb:A6NLS5|uniprotkb:Q5I022|uniprotkb:Q6PFW4|uniprotkb:Q71RH0|uniprotkb:Q8IW18|uniprotkb:Q9H0M8|uniprotkb:Q9H5L8|uniprotkb:Q9H9T2|uniprotkb:A1L4Q3|ensembl:ENSP00000328287	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:rn123_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF123(gene name synonym)|uniprotkb:FP1477(orf name)|uniprotkb:RNF123(gene name)|psi-mi:RNF123(display_short)|uniprotkb:KPC1(gene name synonym)|uniprotkb:RING finger protein 123(gene name synonym)|uniprotkb:Kip1 ubiquitination-promoting complex protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339911|imex:IM-11696-759	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_071347.2|refseq:XP_011532297.1|refseq:XP_006713348.1|ensembl:ENSG00000164068(gene)|ensembl:ENST00000327697(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR035773|interpro:IPR043136|rcsb pdb:2MA6|reactome:R-HSA-5689880|reactome:R-HSA-983168|refseq:XP_016862507.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:g+T7G1ZM4jNkUY+M0KP+MF3eeJU9606	intact-crc:4663B14C2C60310C|rigid:ODKUpYxdFGkGt3WpTMJvUvl1Fbk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BY78	uniprotkb:Q96B02	intact:EBI-2129375|uniprotkb:Q542Y8|intact:EBI-2339452|intact:EBI-28972797|ensembl:ENSP00000312439	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:rnf26_human(display_long)|uniprotkb:RNF26(gene name)|psi-mi:RNF26(display_short)|uniprotkb:RING finger protein 26(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339914|imex:IM-11696-760	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000312439|refseq:NP_114404.1|ensembl:ENSG00000173456(gene)|ensembl:ENST00000311413(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007032"(endosome organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040089	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:R0awMKLLQSLU9zjVe/ivOWeYjnE9606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:CF4C4D4074654D34|rigid:k/vR7FHHz9t+Sn5FmTR3oDw8w9E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q8ND25	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339917|imex:IM-11696-761	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	intact-crc:4BA5F02C4EB5BA94|rigid:73758sTN5/B//yupdNaNq8vs7IY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCN8	uniprotkb:Q8IX04	intact:EBI-2339921|uniprotkb:Q9BRI5|uniprotkb:A2RUD3|ensembl:ENSP00000248958	intact:EBI-2339926|uniprotkb:Q96FF5|uniprotkb:Q6P2F0|uniprotkb:Q9NUX7|uniprotkb:B2RB69|uniprotkb:F5H6L6|uniprotkb:B4DL43|uniprotkb:H7BYD6|ensembl:ENSP00000379500	psi-mi:sdf2l_human(display_long)|uniprotkb:SDF2L1(gene name)|psi-mi:SDF2L1(display_short)|uniprotkb:PWP1-interacting protein 8(gene name synonym)|uniprotkb:UNQ1941/PRO4424(orf name)	psi-mi:uevld_human(display_long)|uniprotkb:UEVLD(gene name)|psi-mi:UEVLD(display_short)|uniprotkb:UEV3(gene name synonym)|uniprotkb:EV and lactate/malate dehydrogenase domain-containing protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339920|imex:IM-11696-762	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071327.2|ensembl:ENSG00000128228(gene)|ensembl:ENST00000248958(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0101031"(chaperone complex)|interpro:IPR016093(MIR motif)|interpro:IPR036300|mint:Q9HCN8	refseq:NP_001035787.1|refseq:NP_060784.3|refseq:NP_001284700.1|refseq:NP_001248312.1|refseq:NP_001248314.1|refseq:NP_001248311.1|refseq:NP_001248315.1|ensembl:ENSG00000151116(gene)|ensembl:ENST00000396197(transcript)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0015031"(protein transport)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR022383|interpro:IPR036291|rcsb pdb:2I6T|rcsb pdb:3DL2	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:0vAPKCqCGpCARkmy7ZsTccxScgk9606	rogid:ZoLQ2ktG7JpK/ocZ+iC65EG5vrc9606	intact-crc:FDAC94BACE7D3213|rigid:k713GKWDAv6t7kLEGBAOUO11+ZI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96C23	uniprotkb:Q8IX04	intact:EBI-2339935|uniprotkb:Q8NIA2|uniprotkb:V9HWA8|uniprotkb:Q53RY1|ensembl:ENSP00000272252	intact:EBI-2339926|uniprotkb:Q96FF5|uniprotkb:Q6P2F0|uniprotkb:Q9NUX7|uniprotkb:B2RB69|uniprotkb:F5H6L6|uniprotkb:B4DL43|uniprotkb:H7BYD6|ensembl:ENSP00000379500	psi-mi:galm_human(display_long)|uniprotkb:GALM(gene name)|psi-mi:GALM(display_short)|uniprotkb:Aldose 1-epimerase(gene name synonym)|uniprotkb:BLOCK25(orf name)	psi-mi:uevld_human(display_long)|uniprotkb:UEVLD(gene name)|psi-mi:UEVLD(display_short)|uniprotkb:UEV3(gene name synonym)|uniprotkb:EV and lactate/malate dehydrogenase domain-containing protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339940|imex:IM-11696-763	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011530842.1|refseq:NP_620156.1|ensembl:ENSG00000143891(gene)|ensembl:ENST00000272252(transcript)|go:"GO:0004034"(aldose 1-epimerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0033499"(galactose catabolic process via UDP-galactose)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008183(Aldose 1-epimerase)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR014718(Glycoside hydrolase-type carbohydrate-binding, subgroup)|interpro:IPR015443(Aldose-1-epimerase)|interpro:IPR018052|rcsb pdb:1SNZ|rcsb pdb:1SO0	refseq:NP_001035787.1|refseq:NP_060784.3|refseq:NP_001284700.1|refseq:NP_001248312.1|refseq:NP_001248314.1|refseq:NP_001248311.1|refseq:NP_001248315.1|ensembl:ENSG00000151116(gene)|ensembl:ENST00000396197(transcript)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0015031"(protein transport)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR022383|interpro:IPR036291|rcsb pdb:2I6T|rcsb pdb:3DL2	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:NnkxaSj9BMRBugZpwoSMBYpfsf49606	rogid:ZoLQ2ktG7JpK/ocZ+iC65EG5vrc9606	intact-crc:9A48043E3AC40BEB|rigid:uKeoyiaOaez1u0u81G1chY6iMng	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z7E8	uniprotkb:Q15024	intact:EBI-1783287|uniprotkb:Q3B841|uniprotkb:Q5I0X2|uniprotkb:Q6IS04|uniprotkb:Q6P7P2|uniprotkb:Q96MV4|uniprotkb:Q9BVX5|uniprotkb:Q9UGL6|uniprotkb:B4DF92|uniprotkb:Q29SN7|ensembl:ENSP00000292211	intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564	psi-mi:ub2q1_human(display_long)|uniprotkb:UBE2Q1(gene name)|psi-mi:UBE2Q1(display_short)|uniprotkb:NICE5(gene name synonym)|uniprotkb:UBE2Q(gene name synonym)|uniprotkb:PRO3094(orf name)|uniprotkb:Ubiquitin-protein ligase Q1(gene name synonym)|uniprotkb:Ubiquitin carrier protein Q1(gene name synonym)|uniprotkb:Protein NICE-5(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme Q1(gene name synonym)	psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339943|imex:IM-11696-764	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060052.3|ensembl:ENSG00000160714(gene)|ensembl:ENST00000292211(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001967"(suckling behavior)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007566"(embryo implantation)|go:"GO:0007617"(mating behavior)|go:"GO:0009566"(fertilization)|go:"GO:0030175"(filopodium)|go:"GO:0061458"(reproductive system development)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070459"(prolactin secretion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2QGX|reactome:R-HSA-983168	refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Jxlo/WdqxS0sfr76bmPqj9AnYE09606	rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606	intact-crc:C2F5ADEBC1DB4BE5|rigid:CRi3B96AWHISDZ5mkx8AiqDYjS4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0C9	uniprotkb:Q99729	intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687	intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339965|imex:IM-11696-765	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168	refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606	intact-crc:E7FF75CA983BE883|rigid:kom134vAqNv0HDjsSvAZk27NtQ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43121	uniprotkb:Q9C0C9	intact:EBI-2339969|uniprotkb:Q6ZTR2|uniprotkb:Q6PHR3|uniprotkb:O95812|uniprotkb:Q59E86|ensembl:ENSP00000264036	intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687	psi-mi:muc18_human(display_long)|uniprotkb:MCAM(gene name)|psi-mi:MCAM(display_short)|uniprotkb:MUC18(gene name synonym)|uniprotkb:Melanoma-associated antigen MUC18(gene name synonym)|uniprotkb:Melanoma cell adhesion molecule(gene name synonym)|uniprotkb:Melanoma-associated antigen A32(gene name synonym)|uniprotkb:S-endo 1 endothelial-associated antigen(gene name synonym)|uniprotkb:Cell surface glycoprotein P1H12(gene name synonym)	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339968|imex:IM-11696-766	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006491.2|dip:DIP-52791N|ensembl:ENSG00000076706(gene)|ensembl:ENST00000264036(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003094"(glomerular filtration)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0061042"(vascular wound healing)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:6LYN|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034	refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:f2hDslNdU/yJ8Ni66Wnsr1YE7Uw9606	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	intact-crc:6C232CC13E24F7F8|rigid:0nxsJ9MhKFvJhZKhh7cJ5LB00kU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0C9	uniprotkb:P67809	intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687	intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339979|imex:IM-11696-767	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168	refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606	intact-crc:325BD2F5E3B5A1A3|rigid:An7+n0Mpi3QPmiQ2xGR7CzTJL6Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0C9	uniprotkb:Q15102	intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687	intact:EBI-711522|uniprotkb:Q53X88|ensembl:ENSP00000262890|ensembl:ENSP00000444935	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	psi-mi:pa1b3_human(display_long)|uniprotkb:PAFAH1B3(gene name)|psi-mi:PAFAH1B3(display_short)|uniprotkb:PAFAHG(gene name synonym)|uniprotkb:PAF acetylhydrolase 29 kDa subunit(gene name synonym)|uniprotkb:PAF-AH subunit gamma(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339982|imex:IM-11696-768	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168	go:"GO:0016042"(lipid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047179"(platelet-activating factor acetyltransferase activity)|interpro:IPR013830(Esterase, SGNH hydrolase-type)|interpro:IPR036514|mint:Q15102|reactome:R-HSA-6811436|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0016020"(membrane)|ensembl:ENSG00000079462(gene)|ensembl:ENST00000262890(transcript)|ensembl:ENST00000538771(transcript)|go:"GO:0003847"(1-alkyl-2-acetylglycerophosphocholine esterase activity)|go:"GO:0005737"(cytoplasm)|refseq:NP_001139411.1|refseq:NP_001139412.1|refseq:NP_002564.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	rogid:yxVKkXAs2AmH+fZFUW+hZN889k89606	intact-crc:5688B4C1001E8514|rigid:IGwOTEoQl1FckdZ8yvZyQ5mHnOg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P30050	uniprotkb:Q9C0C9	intact:EBI-352743|uniprotkb:Q6PB27|uniprotkb:Q5VVV2|ensembl:ENSP00000354739	intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687	psi-mi:rl12_human(display_long)|uniprotkb:RPL12(gene name)|psi-mi:RPL12(display_short)|uniprotkb:Large ribosomal subunit protein uL11(gene name synonym)	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339985|imex:IM-11696-769	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000967.1|ensembl:ENSG00000197958(gene)|ensembl:ENST00000361436(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR020783|interpro:IPR020784|interpro:IPR020785|interpro:IPR036769|interpro:IPR036796|mint:P30050|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:TNPEtl60cILofaPzUznvZiw6D7E9606	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	intact-crc:75703A5D53547BC4|rigid:E7b+vWurfd10WTKLeHUqgL4IQeM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47914	uniprotkb:Q9C0C9	intact:EBI-714039|uniprotkb:Q6IPY3|ensembl:ENSP00000418346|ensembl:ENSP00000418868|ensembl:ENSP00000420673|ensembl:ENSP00000294189|ensembl:ENSP00000417048|ensembl:ENSP00000418153|uniprotkb:B2R4M8|uniprotkb:A8K0H3	intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687	psi-mi:rl29_human(display_long)|uniprotkb:Cell surface heparin-binding protein HIP(gene name synonym)|uniprotkb:RPL29(gene name)|psi-mi:RPL29(display_short)|uniprotkb:Large ribosomal subunit protein eL29(gene name synonym)	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339988|imex:IM-11696-770	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000294189(transcript)|ensembl:ENST00000466397(transcript)|ensembl:ENST00000475248(transcript)|ensembl:ENST00000479017(transcript)|ensembl:ENST00000492277(transcript)|ensembl:ENST00000495383(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007566"(embryo implantation)|go:"GO:0008201"(heparin binding)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR002673(Ribosomal protein L29e)|mint:P47914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|ensembl:ENSG00000162244(gene)|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000983.1|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339	refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:XZUSMDDzycAi6QEXYbljXaeVg0U9606	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	intact-crc:3B0859C0713B9B5E|rigid:Our7xVFv2lchiJTSvxzpwSO+PaA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0C9	uniprotkb:P62081	intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687	intact:EBI-354360|uniprotkb:Q6IPH1|uniprotkb:P23821|uniprotkb:P24818|uniprotkb:Q57Z92|ensembl:ENSP00000385018|ensembl:ENSP00000385286|ensembl:ENSP00000495273|ensembl:ENSP00000496654|ensembl:ENSP00000496757	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	psi-mi:rs7_human(display_long)|uniprotkb:RPS7(gene name)|psi-mi:RPS7(display_short)|uniprotkb:Small ribosomal subunit protein eS7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339991|imex:IM-11696-771	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168	refseq:NP_001002.1|ensembl:ENSG00000171863(gene)|ensembl:ENST00000403564(transcript)|ensembl:ENST00000406376(transcript)|ensembl:ENST00000462576(transcript)|ensembl:ENST00000645674(transcript)|ensembl:ENST00000646909(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000554(Ribosomal protein S7e)|mint:P62081|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6G4S	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	rogid:l4aG6I34lmzYhNapbdv2CAAwRwg9606	intact-crc:5A8F2AF3DD6D15FA|rigid:iIHiy3CVGgfE2CFIjvcvV/Jc8KQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P60866	uniprotkb:Q9C0C9	intact:EBI-353105|uniprotkb:P17075|uniprotkb:Q5M8S9|uniprotkb:B2R4F4|uniprotkb:B4DW28|ensembl:ENSP00000009589|ensembl:ENSP00000427788|ensembl:ENSP00000503327|ensembl:ENSP00000504123|ensembl:ENSP00000504154|ensembl:ENSP00000504670	intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687	psi-mi:rs20_human(display_long)|uniprotkb:RPS20(gene name)|psi-mi:RPS20(display_short)|uniprotkb:Small ribosomal subunit protein uS10(gene name synonym)	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339994|imex:IM-11696-772	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001014.1|refseq:NP_001139699.1|dip:DIP-31245N|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|ensembl:ENSG00000008988(gene)|ensembl:ENST00000009589(transcript)|ensembl:ENST00000521262(transcript)|ensembl:ENST00000676461(transcript)|ensembl:ENST00000676918(transcript)|ensembl:ENST00000678039(transcript)|ensembl:ENST00000678683(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR001848(Ribosomal protein S10)|interpro:IPR005729(Ribosomal protein S10, eukaryotic/archaeal)|interpro:IPR018268|interpro:IPR027486|interpro:IPR036838|mint:P60866|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:6xNxX+eP59AOm0KraCysRHUqMFw9606	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	intact-crc:A6C8DAEB0039CF24|rigid:U98FHtosBIFhP41ivOiKFDThuEs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0C9	uniprotkb:P62987	intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687	intact:EBI-357304|ensembl:ENSP00000388107|ensembl:ENSP00000396910|ensembl:ENSP00000470419|ensembl:ENSP00000470507|ensembl:ENSP00000471062|ensembl:ENSP00000471464|ensembl:ENSP00000471622|ensembl:ENSP00000472264|ensembl:ENSP00000472545|ensembl:ENSP00000473048|uniprotkb:P14793|uniprotkb:Q9BX98|uniprotkb:Q9UPK7|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LBL4|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	psi-mi:rl40_human(display_long)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:CEP52(gene name synonym)|uniprotkb:Ubiquitin A-52 residue ribosomal protein fusion product 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340000|imex:IM-11696-774	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168	ensembl:ENSG00000221983(gene)|ensembl:ENST00000430157(transcript)|ensembl:ENST00000442744(transcript)|ensembl:ENST00000595158(transcript)|rcsb pdb:2MBH|rcsb pdb:2MJB|rcsb pdb:2MUR|ensembl:ENST00000595683(transcript)|ensembl:ENST00000596273(transcript)|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBD|ensembl:ENST00000596304(transcript)|rcsb pdb:2NBE|rcsb pdb:2RSU|rcsb pdb:4HJK|ensembl:ENST00000597451(transcript)|ensembl:ENST00000598780(transcript)|rcsb pdb:4JIO|rcsb pdb:4P4H|rcsb pdb:4PIG|ensembl:ENST00000599551(transcript)|ensembl:ENST00000599595(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:4PIH|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017085"(response to insecticide)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038587|mint:P62987|rcsb pdb:2LJ5|rcsb pdb:4PIJ|rcsb pdb:4RF0|rcsb pdb:4S1Z|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4XKL|rcsb pdb:5AJ0|rcsb pdb:5GO7|rcsb pdb:5GO8|rcsb pdb:5GOB|rcsb pdb:5GOC|rcsb pdb:5GOD|rcsb pdb:5GOG|rcsb pdb:5GOH|rcsb pdb:5GOI|rcsb pdb:5GOJ|rcsb pdb:5GOK|rcsb pdb:5HPK|rcsb pdb:5HPL|rcsb pdb:5HPS|rcsb pdb:5HPT|rcsb pdb:5J26|rcsb pdb:5J8P|rcsb pdb:5JBV|rcsb pdb:5JBY|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:4RF1|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7AY1|rcsb pdb:7BHP|rcsb pdb:7M3Q|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|rcsb pdb:6Z6N|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-69231|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|refseq:NP_001029102.1|refseq:NP_003324.1|refseq:NP_001307947.1|refseq:NP_001307948.1|refseq:NP_001307949.1|refseq:NP_001307946.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	rogid:x9O/Pbww4D28M1+hIj+p0xrUXgU9606	intact-crc:E06445D749DBCF77|rigid:KYNkkfrkKyGgpnL/GjBnR9TIx30	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0C9	uniprotkb:P51532	intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687	intact:EBI-302489|uniprotkb:O95052|uniprotkb:Q9HBD3|uniprotkb:B1A8Z4|uniprotkb:B1A8Z5|uniprotkb:B1A8Z6|uniprotkb:B1A8Z7|uniprotkb:E9PBR8|ensembl:ENSP00000343896|ensembl:ENSP00000395654	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	psi-mi:smca4_human(display_long)|uniprotkb:SMARCA4(gene name)|psi-mi:SMARCA4(display_short)|uniprotkb:BRG1(gene name synonym)|uniprotkb:SNF2B(gene name synonym)|uniprotkb:SNF2L4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:BAF190A(gene name synonym)|uniprotkb:Mitotic growth and transcription activator(gene name synonym)|uniprotkb:Protein BRG-1(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2339997|imex:IM-11696-773	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168	refseq:NP_001122316.1|refseq:NP_003063.2|refseq:NP_001122317.1|refseq:NP_001122318.1|refseq:NP_001122319.1|refseq:NP_001122320.1|dip:DIP-24249N|refseq:XP_016882654.1|refseq:XP_016882655.1|refseq:XP_016882656.1|refseq:XP_016882657.1|ensembl:ENSG00000127616(gene)|ensembl:ENST00000344626(transcript)|ensembl:ENST00000429416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0002039"(p53 binding)|go:"GO:0003407"(neural retina development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51532|rcsb pdb:2GRC|rcsb pdb:2H60|rcsb pdb:3UVD|rcsb pdb:5DKD|rcsb pdb:5EA1|rcsb pdb:6BGH|rcsb pdb:6HR2|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6SY2|rcsb pdb:6ZS2|reactome:R-HSA-1266695|reactome:R-HSA-201722|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-8939243|reactome:R-HSA-9619665	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	rogid:Ztr+2IXfAxueSUaNYG2A47HoMes9606	intact-crc:9E718AE3B301EBBE|rigid:afgYDDqm+kElx+I9fbGwykpLmzs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0C9	uniprotkb:Q9HD64	intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687	intact:EBI-2340004|uniprotkb:Q5JPN8|uniprotkb:Q8WWG6|uniprotkb:Q969J6|uniprotkb:Q5JPP0|uniprotkb:A6NJ94|uniprotkb:Q5JPP3|uniprotkb:Q8WWG5|ensembl:ENSP00000364752|ensembl:ENSP00000364766|ensembl:ENSP00000430130	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	psi-mi:xage1_human(display_long)|uniprotkb:XAGE1A(gene name)|psi-mi:XAGE1A(display_short)|uniprotkb:XAGE1B(gene name)|psi-mi:XAGE1B(display_short)|uniprotkb:GAGED2(gene name synonym)|uniprotkb:XAGE1(gene name synonym)|uniprotkb:Cancer/testis antigen 12.1(gene name synonym)|uniprotkb:G antigen family D member 2(gene name synonym)|uniprotkb:XAGE1C(gene name synonym)|uniprotkb:XAGE1D(gene name synonym)|uniprotkb:XAGE1E(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340003|imex:IM-11696-775	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168	refseq:NP_001091063.2|refseq:NP_001091065.1|refseq:NP_001091073.2|refseq:NP_001091074.1|ensembl:ENSG00000204379(gene)|ensembl:ENSG00000204382(gene)|ensembl:ENST00000375602(transcript)|ensembl:ENST00000375616(transcript)|ensembl:ENST00000518075(transcript)|interpro:IPR008625(GAGE)|refseq:XP_016885236.1|refseq:XP_016885238.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	rogid:dBcO1A1wq9xPNPR1cWYcCDYweiA9606	intact-crc:7C9712BB530833A1|rigid:OKAI2zUjj4cTzQXDdWvShHjf1oE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0C9	uniprotkb:Q86WJ1	intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687	intact:EBI-2340020|intact:EBI-2857214|uniprotkb:Q53EZ3|uniprotkb:Q9NVV8|uniprotkb:Q86XH3|uniprotkb:Q5VXX7|uniprotkb:A5YM64|uniprotkb:Q6PK83|uniprotkb:Q96SP3|uniprotkb:Q9BVJ1|uniprotkb:Q6DD94|uniprotkb:Q96HF7|uniprotkb:B4DDE1|uniprotkb:B5MDZ7|ensembl:ENSP00000358262	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	psi-mi:chd1l_human(display_long)|uniprotkb:CHD1L(gene name)|psi-mi:CHD1L(display_short)|uniprotkb:ALC1(gene name synonym)|uniprotkb:Amplified in liver cancer protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340034|imex:IM-11696-776	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168	refseq:NP_001243267.1|refseq:NP_004275.4|dip:DIP-48933N|refseq:NP_001335382.1|refseq:NP_078844.2|refseq:NP_001243266.1|refseq:NP_001335385.1|refseq:NP_001335386.1|refseq:NP_001335387.1|refseq:NP_001335388.1|refseq:NP_001335389.1|refseq:NP_001335390.1|refseq:NP_001335391.1|refseq:NP_001335392.1|refseq:NP_001335393.1|refseq:NP_001335394.1|refseq:NP_001335395.1|ensembl:ENSG00000131778(gene)|ensembl:ENST00000369258(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR031053|interpro:IPR038718|interpro:IPR043472|mint:Q86WJ1|rcsb pdb:6ZHX|rcsb pdb:6ZHY|reactome:R-HSA-5696395|reactome:R-HSA-5696400	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2018/09/18	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	rogid:e8j47togv1uhkm+TwhWyG6OxiiE9606	intact-crc:5EEF3328BD727CF7|rigid:VJcJaEe0EE7PB2rEU5Z1UkVccl0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P60520	uniprotkb:Q9C0C9	intact:EBI-720116|uniprotkb:O08765|uniprotkb:Q9DCP8|uniprotkb:Q9UQF7|intact:EBI-3239397|ensembl:ENSP00000037243|intact:EBI-2973440|uniprotkb:Q6FG91	intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687	psi-mi:gbrl2_human(display_long)|uniprotkb:"GABA(A) receptor-associated protein-like 2"(gene name synonym)|uniprotkb:Golgi-associated ATPase enhancer of 16 kDa(gene name synonym)|uniprotkb:General protein transport factor p16(gene name synonym)|uniprotkb:Ganglioside expression factor 2(gene name synonym)|uniprotkb:MAP1 light chain 3-related protein(gene name synonym)|uniprotkb:GABARAPL2(gene name)|psi-mi:GABARAPL2(display_short)|uniprotkb:FLC3A(gene name synonym)|uniprotkb:GEF2(gene name synonym)	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340037|imex:IM-11696-777	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009216.1|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0051117"(ATPase binding)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:4CO7|rcsb pdb:6H8C|rcsb pdb:7LK3|reactome:R-HSA-1632852|reactome:R-HSA-8854214|ensembl:ENSG00000034713(gene)|ensembl:ENST00000037243(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|dip:DIP-35051N	refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hABWDldI6+CiLNmy6WDCNQhm54Q9606	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	intact-crc:D18E0317E654781E|rigid:H7c+X97uInc5TALATCj9mwEeBX0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0C9	uniprotkb:Q9HAJ7	intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687	intact:EBI-2340040|uniprotkb:E9PAU7|uniprotkb:E9PAY2|ensembl:ENSP00000297109	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	psi-mi:sp30l_human(display_long)|uniprotkb:SAP30L(gene name)|psi-mi:SAP30L(display_short)|uniprotkb:NS4ATP2(gene name synonym)|uniprotkb:Sin3-associated protein p30-like(gene name synonym)|uniprotkb:Sin3 corepressor complex subunit SAP30L(gene name synonym)|uniprotkb:HCV non-structural protein 4A-transactivated protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340044|imex:IM-11696-778	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168	refseq:NP_001124534.1|refseq:NP_001124535.1|refseq:NP_078908.1|ensembl:ENSG00000164576(gene)|ensembl:ENST00000297109(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042393"(histone binding)|go:"GO:0044378"(non-sequence-specific DNA binding, bending)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|interpro:IPR024145|interpro:IPR025717|interpro:IPR025718|interpro:IPR038291|rcsb pdb:2N1U|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-9679191	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	rogid:P+sxdU4GuYQwPnJPJSsBUwF6VnY9606	intact-crc:CA5629A8E2BA49E0|rigid:2CeE/S5Vp8xxu/VoPsOCErmB7cc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-2342203	uniprotkb:Q9C0C9	genbank_nucl_gi:554633	intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687	psi-mi:al554633_hum_protein(display_short)|psi-mi:EBI-2342203(display_long)	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340047|imex:IM-11696-579	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	-	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	intact-crc:B63DA981F00F99D1	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96H22	uniprotkb:Q9H8T0	intact:EBI-2340053|uniprotkb:Q9NZ83|uniprotkb:B3KN53|uniprotkb:C9JJM5|uniprotkb:D3DUK8|uniprotkb:A8MZE6|uniprotkb:B4DJD1|uniprotkb:B4DPY7|uniprotkb:E7ES30|uniprotkb:E7ETS3|ensembl:ENSP00000305608	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	psi-mi:cenpn_human(display_long)|uniprotkb:CENPN(gene name)|psi-mi:CENPN(display_short)|uniprotkb:C16orf60(gene name synonym)|uniprotkb:ICEN32(gene name synonym)|uniprotkb:Interphase centromere complex protein 32(gene name synonym)|uniprotkb:BM-309(orf name)	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340052|imex:IM-11696-780	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006721299.1|refseq:NP_001094094.2|refseq:NP_060925.2|refseq:NP_001094095.2|refseq:NP_001257402.1|refseq:NP_001257403.1|refseq:XP_016878945.1|ensembl:ENSG00000166451(gene)|ensembl:ENST00000305850(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR007902(CHL4)|mint:Q96H22|rcsb pdb:6C0W|rcsb pdb:6EQT|rcsb pdb:6MUO|rcsb pdb:6MUP|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:6BUZ	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:mZN9Zgmz2AYSbhAFGobCUH++bnY9606	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	intact-crc:B545976DABB6BD99|rigid:mQXd2zxCmIWr0pgYzQ1hRhEJZVw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H8T0	uniprotkb:P58557	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	intact:EBI-2114647|uniprotkb:D3DSN2|uniprotkb:B7WPA9|uniprotkb:B7WPF7|ensembl:ENSP00000329614|ensembl:ENSP00000380805|ensembl:ENSP00000380813	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:ybey_human(display_long)|uniprotkb:YBEY(gene name)|psi-mi:YBEY(display_short)|uniprotkb:C21orf57(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340049|imex:IM-11696-779	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)	refseq:NP_478061.1|refseq:NP_001300951.1|refseq:NP_001300952.1|refseq:NP_001300953.1|refseq:NP_001300954.1|refseq:NP_001300955.1|ensembl:ENSG00000182362(gene)|ensembl:ENST00000329319(transcript)|ensembl:ENST00000397691(transcript)|ensembl:ENST00000397701(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR002036(Protein of unknown function UPF0054)|interpro:IPR020549|interpro:IPR023091|mint:P58557	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	rogid:VOjeUF0iThxy1T2ywZGHB8ILorc9606	intact-crc:6501C71752205A22|rigid:JwA9iGFK85WIatpVUthU5V2CQ0I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96A84	uniprotkb:Q9H8T0	intact:EBI-2340062|uniprotkb:B0QYK6|uniprotkb:Q86SS7|uniprotkb:Q6ICG1	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	psi-mi:emid1_human(display_long)|uniprotkb:EMID1(gene name)|psi-mi:EMID1(display_short)|uniprotkb:EMU1(gene name synonym)|uniprotkb:Emilin and multimerin domain-containing protein 1(gene name synonym)	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340061|imex:IM-11696-781	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_597712.2|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR011489(EMI)|refseq:NP_001254824.1|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0031012"(extracellular matrix)	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:kWMVjpIKt3Ga27zQbt3yLsTWl2k9606	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	intact-crc:C97595F852B6BC7B|rigid:g9RXDUBL9AGvzV/U4MUUQrJWvn4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H8T0	uniprotkb:P58546	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	intact:EBI-1051736|ensembl:ENSP00000376800	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:mtpn_human(display_long)|uniprotkb:Protein V-1(gene name synonym)|uniprotkb:MTPN(gene name)|psi-mi:MTPN(display_short)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340070|imex:IM-11696-782	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)	refseq:NP_665807.1|ensembl:ENSG00000105887(gene)|ensembl:ENST00000393085(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006584"(catecholamine metabolic process)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010557"(positive regulation of macromolecule biosynthetic process)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2000812"(regulation of barbed-end actin filament capping)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P58546|rcsb pdb:3AAA|rcsb pdb:7DF7|rcsb pdb:7DSA|rcsb pdb:7DSB|dip:DIP-50234N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	rogid:kdJ8vNN4yI2ye49iYUNAtH538b49606	intact-crc:AE6C710BE4FB37C4|rigid:IqpAxrmdPc/x3R2ueYkQMqtLaNM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16774	uniprotkb:Q9H832	intact:EBI-2340074|uniprotkb:B1ANH1|ensembl:ENSP00000317659|ensembl:ENSP00000355677|ensembl:ENSP00000355679|ensembl:ENSP00000355687|ensembl:ENSP00000355691	intact:EBI-720977|uniprotkb:A6N8M6|uniprotkb:Q7L354|uniprotkb:Q8TCM4|uniprotkb:Q9H893|uniprotkb:A6NC60|ensembl:ENSP00000354201	psi-mi:kgua_human(display_long)|uniprotkb:GUK1(gene name)|psi-mi:GUK1(display_short)|uniprotkb:GMK(gene name synonym)|uniprotkb:GMP kinase(gene name synonym)|uniprotkb:GMPK(gene name synonym)|uniprotkb:Guanylate kinase 1(gene name synonym)	psi-mi:ube2z_human(display_long)|uniprotkb:Ubiquitin-protein ligase Z(gene name synonym)|uniprotkb:Ubiquitin carrier protein Z(gene name synonym)|uniprotkb:Uba6-specific E2 conjugating enzyme 1(gene name synonym)|uniprotkb:UBE2Z(gene name)|psi-mi:UBE2Z(display_short)|uniprotkb:HOYS7(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme Z(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340073|imex:IM-11696-783	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000849.1|refseq:NP_001152863.1|refseq:NP_001229768.1|refseq:NP_001152862.1|refseq:NP_001229769.1|ensembl:ENSG00000143774(gene)|ensembl:ENST00000312726(transcript)|ensembl:ENST00000366716(transcript)|ensembl:ENST00000366718(transcript)|ensembl:ENST00000366726(transcript)|ensembl:ENST00000366730(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006163"(purine nucleotide metabolic process)|go:"GO:0006185"(dGDP biosynthetic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0034436"(glycoprotein transport)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046054"(dGMP metabolic process)|go:"GO:0046060"(dATP metabolic process)|go:"GO:0046711"(GDP biosynthetic process)|go:"GO:0046939"(nucleotide phosphorylation)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR017665(Guanylate kinase, sub-group)|interpro:IPR020590|interpro:IPR027417|rcsb pdb:6NUI|reactome:R-HSA-2161541|reactome:R-HSA-499943	refseq:NP_075567.2|ensembl:ENSG00000159202(gene)|ensembl:ENST00000360943(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:5A4P|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:XJ4OokT2+8LY9P1bUKmFwmRXt249606	rogid:ha+cN8Y8XYZFrRnAQC9BRiMaUL89606	intact-crc:7502D19A341076EA|rigid:Yqz//29F3AWsPA3/wC5UgyrtRn8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H832	uniprotkb:O75843	intact:EBI-720977|uniprotkb:A6N8M6|uniprotkb:Q7L354|uniprotkb:Q8TCM4|uniprotkb:Q9H893|uniprotkb:A6NC60|ensembl:ENSP00000354201	intact:EBI-373637|uniprotkb:O75504|ensembl:ENSP00000312442|ensembl:ENSP00000380309|uniprotkb:D3DS51	psi-mi:ube2z_human(display_long)|uniprotkb:Ubiquitin-protein ligase Z(gene name synonym)|uniprotkb:Ubiquitin carrier protein Z(gene name synonym)|uniprotkb:Uba6-specific E2 conjugating enzyme 1(gene name synonym)|uniprotkb:UBE2Z(gene name)|psi-mi:UBE2Z(display_short)|uniprotkb:HOYS7(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme Z(gene name synonym)	psi-mi:ap1g2_human(display_long)|uniprotkb:AP1G2(gene name)|psi-mi:AP1G2(display_short)|uniprotkb:Gamma2-adaptin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340080|imex:IM-11696-784	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075567.2|ensembl:ENSG00000159202(gene)|ensembl:ENST00000360943(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:5A4P|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_003908.1|ensembl:ENSG00000213983(gene)|ensembl:ENST00000308724(transcript)|ensembl:ENST00000397120(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030133"(transport vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017107(Adaptor protein complex AP-1, gamma subunit)|mint:O75843|rcsb pdb:2E9G|rcsb pdb:2YMT|rcsb pdb:3ZHF|rcsb pdb:4BCX|reactome:R-HSA-432720|refseq:XP_005268229.1|refseq:XP_005268230.1|dip:DIP-31185N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ha+cN8Y8XYZFrRnAQC9BRiMaUL89606	rogid:kqOQ44wfiFq2YxrDbVBvofbl9E89606	intact-crc:EB8E3A1A107C8A3F|rigid:Nigh0JmKADC91ST0fSWQUNr7dLY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96S59	uniprotkb:Q9H832	intact:EBI-636085|uniprotkb:A0PJA2|uniprotkb:O94764|uniprotkb:Q6P3T7|uniprotkb:Q7LBR2|uniprotkb:Q7Z7F9|ensembl:ENSP00000011619|uniprotkb:B2R8E1	intact:EBI-720977|uniprotkb:A6N8M6|uniprotkb:Q7L354|uniprotkb:Q8TCM4|uniprotkb:Q9H893|uniprotkb:A6NC60|ensembl:ENSP00000354201	psi-mi:ranb9_human(display_long)|uniprotkb:RanBP7(gene name synonym)|uniprotkb:Ran-binding protein M(gene name synonym)|uniprotkb:BPM90(gene name synonym)|uniprotkb:BPM-L(gene name synonym)|uniprotkb:RANBP9(gene name)|psi-mi:RANBP9(display_short)|uniprotkb:RANBPM(gene name synonym)	psi-mi:ube2z_human(display_long)|uniprotkb:Ubiquitin-protein ligase Z(gene name synonym)|uniprotkb:Ubiquitin carrier protein Z(gene name synonym)|uniprotkb:Uba6-specific E2 conjugating enzyme 1(gene name synonym)|uniprotkb:UBE2Z(gene name)|psi-mi:UBE2Z(display_short)|uniprotkb:HOYS7(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme Z(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340083|imex:IM-11696-785	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005484.2|ensembl:ENSG00000010017(gene)|ensembl:ENST00000011619(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|interpro:IPR035782|interpro:IPR043136|mint:Q96S59|rcsb pdb:5JI7|rcsb pdb:5JI9|rcsb pdb:5JIU|rcsb pdb:7NSC|reactome:R-HSA-373760|reactome:R-HSA-5673001|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|reactome:R-HSA-8851805|refseq:XP_006715008.1	refseq:NP_075567.2|ensembl:ENSG00000159202(gene)|ensembl:ENST00000360943(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:5A4P|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:7jybZidQAgnkobKmGJhZ9xsEeH09606	rogid:ha+cN8Y8XYZFrRnAQC9BRiMaUL89606	intact-crc:A919BA763E2890CC|rigid:3Q9uLxKIMonpQnAlYUtG5nXfmrw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H832	uniprotkb:P61289	intact:EBI-720977|uniprotkb:A6N8M6|uniprotkb:Q7L354|uniprotkb:Q8TCM4|uniprotkb:Q9H893|uniprotkb:A6NC60|ensembl:ENSP00000354201	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	psi-mi:ube2z_human(display_long)|uniprotkb:Ubiquitin-protein ligase Z(gene name synonym)|uniprotkb:Ubiquitin carrier protein Z(gene name synonym)|uniprotkb:Uba6-specific E2 conjugating enzyme 1(gene name synonym)|uniprotkb:UBE2Z(gene name)|psi-mi:UBE2Z(display_short)|uniprotkb:HOYS7(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme Z(gene name synonym)	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340086|imex:IM-11696-786	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075567.2|ensembl:ENSG00000159202(gene)|ensembl:ENST00000360943(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:5A4P|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ha+cN8Y8XYZFrRnAQC9BRiMaUL89606	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	intact-crc:7726C538F60E53BE|rigid:Lo68MpsNh7E9Tz5WLE+9Z3LmjIA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H832	uniprotkb:Q75QN2	intact:EBI-720977|uniprotkb:A6N8M6|uniprotkb:Q7L354|uniprotkb:Q8TCM4|uniprotkb:Q9H893|uniprotkb:A6NC60|ensembl:ENSP00000354201	intact:EBI-2340089|uniprotkb:Q5RKZ3|uniprotkb:Q6P1R5|uniprotkb:Q9NVS6|uniprotkb:Q7Z314|uniprotkb:Q9NWY7|uniprotkb:B2RN92|ensembl:ENSP00000430338	psi-mi:ube2z_human(display_long)|uniprotkb:Ubiquitin-protein ligase Z(gene name synonym)|uniprotkb:Ubiquitin carrier protein Z(gene name synonym)|uniprotkb:Uba6-specific E2 conjugating enzyme 1(gene name synonym)|uniprotkb:UBE2Z(gene name)|psi-mi:UBE2Z(display_short)|uniprotkb:HOYS7(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme Z(gene name synonym)	psi-mi:int8_human(display_long)|uniprotkb:INTS8(gene name)|psi-mi:INTS8(display_short)|uniprotkb:C8orf52(gene name synonym)|uniprotkb:Protein kaonashi-1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340098|imex:IM-11696-787	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075567.2|ensembl:ENSG00000159202(gene)|ensembl:ENST00000360943(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:5A4P|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_060334.2|refseq:XP_016869108.1|ensembl:ENSG00000164941(gene)|ensembl:ENST00000523731(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR038751|rcsb pdb:7CUN|reactome:R-HSA-6807505	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ha+cN8Y8XYZFrRnAQC9BRiMaUL89606	rogid:9fEstP6mNqoKkTZGK70ANCMG7NM9606	intact-crc:79F71E70897C8A74|rigid:w3Qt5TEaqUFDFd+bMEJ7K5FvMfI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6PJ69	uniprotkb:Q9H832	intact:EBI-2130441|uniprotkb:Q4G0F0|uniprotkb:Q6DKJ6|uniprotkb:Q9BRP6|ensembl:ENSP00000269383	intact:EBI-720977|uniprotkb:A6N8M6|uniprotkb:Q7L354|uniprotkb:Q8TCM4|uniprotkb:Q9H893|uniprotkb:A6NC60|ensembl:ENSP00000354201	psi-mi:tri65_human(display_long)|uniprotkb:TRIM65(gene name)|psi-mi:TRIM65(display_short)	psi-mi:ube2z_human(display_long)|uniprotkb:Ubiquitin-protein ligase Z(gene name synonym)|uniprotkb:Ubiquitin carrier protein Z(gene name synonym)|uniprotkb:Uba6-specific E2 conjugating enzyme 1(gene name synonym)|uniprotkb:UBE2Z(gene name)|psi-mi:UBE2Z(display_short)|uniprotkb:HOYS7(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme Z(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340104|imex:IM-11696-789	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_775818.2|refseq:NP_001243053.1|ensembl:ENSG00000141569(gene)|ensembl:ENST00000269383(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010508"(positive regulation of autophagy)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR018957|interpro:IPR043136|rcsb pdb:7JL0|rcsb pdb:7JL2|rcsb pdb:7JL4	refseq:NP_075567.2|ensembl:ENSG00000159202(gene)|ensembl:ENST00000360943(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:5A4P|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:oV3SxWrEWzpj3c5ljfkAOU98XuY9606	rogid:ha+cN8Y8XYZFrRnAQC9BRiMaUL89606	intact-crc:649FE7753495F917|rigid:YIkUeaB0ARNAlvdvlcdyJJrn4rk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TBB1	uniprotkb:Q9H832	intact:EBI-739832|uniprotkb:Q4W5K7|uniprotkb:Q8N4C2|uniprotkb:Q96MJ7|uniprotkb:Q9BY20|ensembl:ENSP00000263925	intact:EBI-720977|uniprotkb:A6N8M6|uniprotkb:Q7L354|uniprotkb:Q8TCM4|uniprotkb:Q9H893|uniprotkb:A6NC60|ensembl:ENSP00000354201	psi-mi:lnx1_human(display_long)|uniprotkb:LNX1(gene name)|psi-mi:LNX1(display_short)|uniprotkb:LNX(gene name synonym)|uniprotkb:Numb-binding protein 1(gene name synonym)|uniprotkb:Ligand of Numb-protein X 1(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 2(gene name synonym)|uniprotkb:PDZRN2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase LNX(gene name synonym)|uniprotkb:UNQ574/PRO1136(orf name)	psi-mi:ube2z_human(display_long)|uniprotkb:Ubiquitin-protein ligase Z(gene name synonym)|uniprotkb:Ubiquitin carrier protein Z(gene name synonym)|uniprotkb:Uba6-specific E2 conjugating enzyme 1(gene name synonym)|uniprotkb:UBE2Z(gene name)|psi-mi:UBE2Z(display_short)|uniprotkb:HOYS7(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme Z(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340101|imex:IM-11696-788	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119800.1|refseq:NP_116011.2|refseq:XP_005265842.1|refseq:XP_016864265.1|ensembl:ENSG00000072201(gene)|ensembl:ENST00000263925(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8TBB1|rcsb pdb:3B76|rcsb pdb:5H7R|rcsb pdb:5H7S|reactome:R-HSA-983168	refseq:NP_075567.2|ensembl:ENSG00000159202(gene)|ensembl:ENST00000360943(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:5A4P|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:tWvePnVxh9yxWl8nQd3KZhCSKKo9606	rogid:ha+cN8Y8XYZFrRnAQC9BRiMaUL89606	intact-crc:1E024E4F0A4D8EEA|rigid:wvBlg2BoJYDoiYb9vecp04tFRKA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WVN8	uniprotkb:Q15024	intact:EBI-2130157|uniprotkb:Q8N4G6|uniprotkb:Q96J08|uniprotkb:B7Z3Q2|uniprotkb:H3BRG2|ensembl:ENSP00000267938	intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564	psi-mi:ub2q2_human(display_long)|uniprotkb:UBE2Q2(gene name)|psi-mi:UBE2Q2(display_short)|uniprotkb:Ubiquitin-protein ligase Q2(gene name synonym)|uniprotkb:Ubiquitin carrier protein Q2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme Q2(gene name synonym)	psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340107|imex:IM-11696-790	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271311.1|refseq:NP_001138807.1|refseq:NP_775740.1|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:1ZUO|reactome:R-HSA-8866652|reactome:R-HSA-983168|go:"GO:0005829"(cytosol)|ensembl:ENSG00000140367(gene)|ensembl:ENST00000267938(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)	refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:3rt+W5KJJW5Hmkl+y5+0VaMpDLU9606	rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606	intact-crc:06DF1CCFD566F37F|rigid:rch4yAj+NtgT0RPeqTpKLnKbfiI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N2K1	uniprotkb:Q712V1	intact:EBI-2340110|uniprotkb:Q96T84|uniprotkb:Q96N26|uniprotkb:Q504T9|uniprotkb:A8MYC7|ensembl:ENSP00000305826|ensembl:ENSP00000353653	intact:EBI-2340116	psi-mi:ub2j2_human(display_long)|uniprotkb:UBE2J2(gene name)|psi-mi:UBE2J2(display_short)|uniprotkb:NCUBE2(gene name synonym)|uniprotkb:Non-canonical ubiquitin-conjugating enzyme 2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme J2(gene name synonym)	psi-mi:q712v1_human(display_long)|uniprotkb:UBE1(gene name)|psi-mi:UBE1(display_short)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340120|imex:IM-11696-791	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538915.1|refseq:XP_011538916.1|refseq:XP_006710396.1|refseq:NP_477515.2|refseq:NP_919440.1|refseq:NP_919296.1|refseq:XP_005244775.1|refseq:XP_005244776.1|ensembl:ENSG00000160087(gene)|ensembl:ENST00000349431(transcript)|ensembl:ENST00000360466(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2F4W|reactome:R-HSA-8866654|reactome:R-HSA-9609523|reactome:R-HSA-983168	interpro:IPR038252|interpro:IPR018965	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wsZGIUcE5bEjsim+d4Ur3DDOJWs9606	rogid:GcyRVEPpk8yUh5I4FdkKobsgqJo9606	intact-crc:809ACB5CD6C00135|rigid:6UEEqnR3J4/oMCeAA7cTuGMLiuM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VU43	uniprotkb:Q8N2K1	intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24	intact:EBI-2340110|uniprotkb:Q96T84|uniprotkb:Q96N26|uniprotkb:Q504T9|uniprotkb:A8MYC7|ensembl:ENSP00000305826|ensembl:ENSP00000353653	psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)	psi-mi:ub2j2_human(display_long)|uniprotkb:UBE2J2(gene name)|psi-mi:UBE2J2(display_short)|uniprotkb:NCUBE2(gene name synonym)|uniprotkb:Non-canonical ubiquitin-conjugating enzyme 2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme J2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340123|imex:IM-11696-792	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000178104(gene)|ensembl:ENST00000313431|ensembl:ENSP00000316434|ensembl:ENST00000369347|ensembl:ENSP00000358353|ensembl:ENST00000369349|ensembl:ENSP00000358355|ensembl:ENST00000369351|ensembl:ENSP00000358357|ensembl:ENSP00000358360|ensembl:ENST00000369356|ensembl:ENSP00000358363|ensembl:ENST00000529945|ensembl:ENSP00000433392|ensembl:ENST00000530472|ensembl:ENSP00000482121|ensembl:ENST00000618462|ensembl:ENSP00000479409|ensembl:ENST00000369354(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0034622"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|mint:Q5VU43|refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N	refseq:XP_011538915.1|refseq:XP_011538916.1|refseq:XP_006710396.1|refseq:NP_477515.2|refseq:NP_919440.1|refseq:NP_919296.1|refseq:XP_005244775.1|refseq:XP_005244776.1|ensembl:ENSG00000160087(gene)|ensembl:ENST00000349431(transcript)|ensembl:ENST00000360466(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2F4W|reactome:R-HSA-8866654|reactome:R-HSA-9609523|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2018/04/06	rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606	rogid:wsZGIUcE5bEjsim+d4Ur3DDOJWs9606	intact-crc:1DC31D10DD82555A|rigid:II0is8tM2RteuNcfYZtv58xTO5k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N2K1	uniprotkb:Q6IPW0	intact:EBI-2340110|uniprotkb:Q96T84|uniprotkb:Q96N26|uniprotkb:Q504T9|uniprotkb:A8MYC7|ensembl:ENSP00000305826|ensembl:ENSP00000353653	intact:EBI-948989	psi-mi:ub2j2_human(display_long)|uniprotkb:UBE2J2(gene name)|psi-mi:UBE2J2(display_short)|uniprotkb:NCUBE2(gene name synonym)|uniprotkb:Non-canonical ubiquitin-conjugating enzyme 2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme J2(gene name synonym)	psi-mi:q6ipw0_human(display_long)|uniprotkb:FLJ10404(gene name)|psi-mi:FLJ10404(display_short)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340126|imex:IM-11696-793	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538915.1|refseq:XP_011538916.1|refseq:XP_006710396.1|refseq:NP_477515.2|refseq:NP_919440.1|refseq:NP_919296.1|refseq:XP_005244775.1|refseq:XP_005244776.1|ensembl:ENSG00000160087(gene)|ensembl:ENST00000349431(transcript)|ensembl:ENST00000360466(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2F4W|reactome:R-HSA-8866654|reactome:R-HSA-9609523|reactome:R-HSA-983168	interpro:IPR029722|refseq:NP_001177875.1|interpro:IPR031802|interpro:IPR029717	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wsZGIUcE5bEjsim+d4Ur3DDOJWs9606	rogid:bbytdP46IZ+IsukrDARew5Z1AUI9606	intact-crc:06C7579DE6B2AB08|rigid:+gqFlKBomUkOYYoTzAfi2zd/pMw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P29597	uniprotkb:Q969M7	intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885	intact:EBI-1056876|uniprotkb:A8K1Z8|uniprotkb:B4DDT9|uniprotkb:B4DFI1|uniprotkb:B4DMK3|uniprotkb:B4DZU2|uniprotkb:B8ZZG2|uniprotkb:C9J212|uniprotkb:H9KVB9|ensembl:ENSP00000272930|ensembl:ENSP00000478474	psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short)	psi-mi:ube2f_human(display_long)|uniprotkb:UBE2F(gene name)|psi-mi:UBE2F(display_short)|uniprotkb:NCE2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 F(gene name synonym)|uniprotkb:NEDD8 protein ligase UBE2F(gene name synonym)|uniprotkb:NEDD8 carrier protein UBE2F(gene name synonym)|uniprotkb:NEDD8-conjugating enzyme 2(gene name synonym)|uniprotkb:RING-type E3 NEDD8 transferase UBE2F(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340129|imex:IM-11696-794	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462	refseq:NP_542409.1|refseq:NP_001265234.1|refseq:NP_001265235.1|refseq:NP_001265236.1|refseq:NP_001265237.1|ensembl:ENSG00000184182(gene)|ensembl:ENST00000272930(transcript)|ensembl:ENST00000612130(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045116"(protein neddylation)|go:"GO:0061654"(NEDD8 conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2EDI|rcsb pdb:3FN1|rcsb pdb:4GBA|reactome:R-HSA-8951664|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606	rogid:Drl/c/EC3fscD9dEi4rEjAz9yTM9606	intact-crc:C08F43967EA6F61D|rigid:JiRQMLP3IHwFOb0FlrHod8Rm/II	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UI10	uniprotkb:Q969M7	intact:EBI-2340132|uniprotkb:Q53RY7|uniprotkb:Q9UIQ9|uniprotkb:Q9UJ95|uniprotkb:Q5BJF4|uniprotkb:Q9UBG4|uniprotkb:Q9BUV9|ensembl:ENSP00000233552	intact:EBI-1056876|uniprotkb:A8K1Z8|uniprotkb:B4DDT9|uniprotkb:B4DFI1|uniprotkb:B4DMK3|uniprotkb:B4DZU2|uniprotkb:B8ZZG2|uniprotkb:C9J212|uniprotkb:H9KVB9|ensembl:ENSP00000272930|ensembl:ENSP00000478474	psi-mi:ei2bd_human(display_long)|uniprotkb:EIF2B4(gene name)|psi-mi:EIF2B4(display_short)|uniprotkb:EIF2BD(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)	psi-mi:ube2f_human(display_long)|uniprotkb:UBE2F(gene name)|psi-mi:UBE2F(display_short)|uniprotkb:NCE2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 F(gene name synonym)|uniprotkb:NEDD8 protein ligase UBE2F(gene name synonym)|uniprotkb:NEDD8 carrier protein UBE2F(gene name synonym)|uniprotkb:NEDD8-conjugating enzyme 2(gene name synonym)|uniprotkb:RING-type E3 NEDD8 transferase UBE2F(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340141|imex:IM-11696-795	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001029288.1|refseq:NP_056451.3|refseq:NP_751945.2|refseq:NP_001305894.1|refseq:NP_001305895.1|refseq:NP_001305896.1|refseq:NP_001305897.1|ensembl:ENSG00000115211(gene)|ensembl:ENST00000347454(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006417"(regulation of translation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0042552"(myelination)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042529|mint:Q9UI10|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731	refseq:NP_542409.1|refseq:NP_001265234.1|refseq:NP_001265235.1|refseq:NP_001265236.1|refseq:NP_001265237.1|ensembl:ENSG00000184182(gene)|ensembl:ENST00000272930(transcript)|ensembl:ENST00000612130(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045116"(protein neddylation)|go:"GO:0061654"(NEDD8 conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2EDI|rcsb pdb:3FN1|rcsb pdb:4GBA|reactome:R-HSA-8951664|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ZCU4mIO5zkmBajIvBRe3b2PZINw9606	rogid:Drl/c/EC3fscD9dEi4rEjAz9yTM9606	intact-crc:8F271B78D785F7D3|rigid:XtUj6axzNE2SVwa+nFyfrkBjqi0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969M7	uniprotkb:P78395	intact:EBI-1056876|uniprotkb:A8K1Z8|uniprotkb:B4DDT9|uniprotkb:B4DFI1|uniprotkb:B4DMK3|uniprotkb:B4DZU2|uniprotkb:B8ZZG2|uniprotkb:C9J212|uniprotkb:H9KVB9|ensembl:ENSP00000272930|ensembl:ENSP00000478474	intact:EBI-348325|ensembl:ENSP00000381726|ensembl:ENSP00000381728|ensembl:ENSP00000384343|ensembl:ENSP00000385198|ensembl:ENSP00000445097|ensembl:ENSP00000445675|ensembl:ENSP00000484066|ensembl:ENSP00000486330|ensembl:ENSP00000486485|uniprotkb:O43481|uniprotkb:Q8IXN8|uniprotkb:B2R6Y7	psi-mi:ube2f_human(display_long)|uniprotkb:UBE2F(gene name)|psi-mi:UBE2F(display_short)|uniprotkb:NCE2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 F(gene name synonym)|uniprotkb:NEDD8 protein ligase UBE2F(gene name synonym)|uniprotkb:NEDD8 carrier protein UBE2F(gene name synonym)|uniprotkb:NEDD8-conjugating enzyme 2(gene name synonym)|uniprotkb:RING-type E3 NEDD8 transferase UBE2F(gene name synonym)	psi-mi:prame_human(display_long)|uniprotkb:PRAME(gene name)|psi-mi:PRAME(display_short)|uniprotkb:MAPE(gene name synonym)|uniprotkb:Preferentially expressed antigen of melanoma(gene name synonym)|uniprotkb:OIP4(gene name synonym)|uniprotkb:Opa-interacting protein 4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340147|imex:IM-11696-797	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_542409.1|refseq:NP_001265234.1|refseq:NP_001265235.1|refseq:NP_001265236.1|refseq:NP_001265237.1|ensembl:ENSG00000184182(gene)|ensembl:ENST00000272930(transcript)|ensembl:ENST00000612130(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045116"(protein neddylation)|go:"GO:0061654"(NEDD8 conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2EDI|rcsb pdb:3FN1|rcsb pdb:4GBA|reactome:R-HSA-8951664|reactome:R-HSA-983168	refseq:NP_001278644.1|refseq:NP_001278645.1|refseq:NP_001278646.1|refseq:NP_001278648.1|ensembl:ENSG00000185686(gene)|ensembl:ENSG00000275013(gene)|interpro:IPR032675|interpro:IPR026271|ensembl:ENST00000398743(transcript)|ensembl:ENST00000402697(transcript)|ensembl:ENST00000405655(transcript)|ensembl:ENST00000539862(transcript)|ensembl:ENST00000543184(transcript)|ensembl:ENST00000617728(transcript)|ensembl:ENST00000626503(transcript)|ensembl:ENST00000628830(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|ensembl:ENST00000398741(transcript)|refseq:NP_006106.1|refseq:NP_996836.1|refseq:NP_996837.1|refseq:NP_996838.1|refseq:NP_996839.1|refseq:NP_001305056.1|refseq:NP_001305055.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Drl/c/EC3fscD9dEi4rEjAz9yTM9606	rogid:VdJSwUPADlQ09QZ6P/x7jEc3fRw9606	intact-crc:595EF3B329612E0B|rigid:1uYXV4PxUllb/ju9GywEsNkWY1Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TBC4	uniprotkb:Q969M7	intact:EBI-717567|uniprotkb:O76088|uniprotkb:Q9NTU3|uniprotkb:A8K027|intact:EBI-2339745|uniprotkb:A6NLB5|ensembl:ENSP00000354340	intact:EBI-1056876|uniprotkb:A8K1Z8|uniprotkb:B4DDT9|uniprotkb:B4DFI1|uniprotkb:B4DMK3|uniprotkb:B4DZU2|uniprotkb:B8ZZG2|uniprotkb:C9J212|uniprotkb:H9KVB9|ensembl:ENSP00000272930|ensembl:ENSP00000478474	psi-mi:uba3_human(display_long)|uniprotkb:Ubiquitin-like modifier-activating enzyme 3(gene name synonym)|uniprotkb:NEDD8-activating enzyme E1C(gene name synonym)|uniprotkb:Ubiquitin-activating enzyme E1C(gene name synonym)|uniprotkb:UBA3(gene name)|psi-mi:UBA3(display_short)|uniprotkb:UBE1C(gene name synonym)	psi-mi:ube2f_human(display_long)|uniprotkb:UBE2F(gene name)|psi-mi:UBE2F(display_short)|uniprotkb:NCE2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 F(gene name synonym)|uniprotkb:NEDD8 protein ligase UBE2F(gene name synonym)|uniprotkb:NEDD8 carrier protein UBE2F(gene name synonym)|uniprotkb:NEDD8-conjugating enzyme 2(gene name synonym)|uniprotkb:RING-type E3 NEDD8 transferase UBE2F(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340144|imex:IM-11696-796	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003959.3|refseq:NP_937838.1|ensembl:ENSG00000144744(gene)|ensembl:ENST00000361055(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006508"(proteolysis)|go:"GO:0007113"(endomitotic cell cycle)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019781"(NEDD8 activating enzyme activity)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045116"(protein neddylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR014929(E2 binding)|interpro:IPR023318|interpro:IPR030468|interpro:IPR033127|interpro:IPR035985|mint:Q8TBC4|rcsb pdb:1R4M|rcsb pdb:1R4N|rcsb pdb:1TT5|rcsb pdb:1Y8X|rcsb pdb:1YOV|rcsb pdb:2LQ7|rcsb pdb:2NVU|rcsb pdb:3DBH|rcsb pdb:3DBL|rcsb pdb:3DBR|rcsb pdb:3FN1|rcsb pdb:3GZN|rcsb pdb:5JJM|reactome:R-HSA-5607761|reactome:R-HSA-5676590|reactome:R-HSA-8951664|reactome:R-HSA-983168	refseq:NP_542409.1|refseq:NP_001265234.1|refseq:NP_001265235.1|refseq:NP_001265236.1|refseq:NP_001265237.1|ensembl:ENSG00000184182(gene)|ensembl:ENST00000272930(transcript)|ensembl:ENST00000612130(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045116"(protein neddylation)|go:"GO:0061654"(NEDD8 conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2EDI|rcsb pdb:3FN1|rcsb pdb:4GBA|reactome:R-HSA-8951664|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:6VcauGap9tDJ780/x06s6QgRr8Y9606	rogid:Drl/c/EC3fscD9dEi4rEjAz9yTM9606	intact-crc:80F969E44379477E|rigid:lJRHSqKGISsXnHyxixU3lqwJXbE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BQA1	uniprotkb:Q969M7	intact:EBI-1237307|uniprotkb:B3KMW6|uniprotkb:Q96GK4|uniprotkb:Q9BWY3|uniprotkb:Q3LID2|uniprotkb:Q53FU2|uniprotkb:Q6JZZ5|uniprotkb:B4DP38|ensembl:ENSP00000235090	intact:EBI-1056876|uniprotkb:A8K1Z8|uniprotkb:B4DDT9|uniprotkb:B4DFI1|uniprotkb:B4DMK3|uniprotkb:B4DZU2|uniprotkb:B8ZZG2|uniprotkb:C9J212|uniprotkb:H9KVB9|ensembl:ENSP00000272930|ensembl:ENSP00000478474	psi-mi:mep50_human(display_long)|uniprotkb:WDR77(gene name)|psi-mi:WDR77(display_short)|uniprotkb:MEP50(gene name synonym)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:Androgen receptor cofactor p44(gene name synonym)|uniprotkb:p44/Mep50(gene name synonym)|uniprotkb:HKMT1069(orf name)|uniprotkb:Nbla10071(orf name)|uniprotkb:WD45(gene name synonym)	psi-mi:ube2f_human(display_long)|uniprotkb:UBE2F(gene name)|psi-mi:UBE2F(display_short)|uniprotkb:NCE2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 F(gene name synonym)|uniprotkb:NEDD8 protein ligase UBE2F(gene name synonym)|uniprotkb:NEDD8 carrier protein UBE2F(gene name synonym)|uniprotkb:NEDD8-conjugating enzyme 2(gene name synonym)|uniprotkb:RING-type E3 NEDD8 transferase UBE2F(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340150|imex:IM-11696-798	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_077007.1|refseq:NP_001303991.1|refseq:NP_001303992.1|refseq:NP_001303993.1|dip:DIP-38172N|ensembl:ENSG00000116455(gene)|ensembl:ENST00000235090(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0034709"(methylosome)|go:"GO:0045495"(pole plasm)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9BQA1|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858	refseq:NP_542409.1|refseq:NP_001265234.1|refseq:NP_001265235.1|refseq:NP_001265236.1|refseq:NP_001265237.1|ensembl:ENSG00000184182(gene)|ensembl:ENST00000272930(transcript)|ensembl:ENST00000612130(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045116"(protein neddylation)|go:"GO:0061654"(NEDD8 conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2EDI|rcsb pdb:3FN1|rcsb pdb:4GBA|reactome:R-HSA-8951664|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:0q4wunYtHalObC8r1wphhelIpr49606	rogid:Drl/c/EC3fscD9dEi4rEjAz9yTM9606	intact-crc:5DB569645C8CF275|rigid:6OJ2OHaKp/23G73iu8RCytIXDl8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IWF7	uniprotkb:Q05193	intact:EBI-2340154	intact:EBI-713135|uniprotkb:A6NLM6|uniprotkb:Q5SYX0|uniprotkb:Q5SYX2|uniprotkb:Q6P3T6|uniprotkb:Q86VD2|ensembl:ENSP00000362014	psi-mi:u2d2l_human(display_long)|uniprotkb:UBE2DNL(gene name)|psi-mi:UBE2DNL(display_short)|uniprotkb:UBE2D2L(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2-like(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2-like(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2D N-terminal-like(gene name synonym)	psi-mi:dyn1_human(display_long)|uniprotkb:DNM1(gene name)|psi-mi:DNM1(display_short)|uniprotkb:DNM(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340153|imex:IM-11696-799	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)	refseq:NP_001005336.1|refseq:NP_004399.2|refseq:NP_001275666.1|refseq:NP_001275667.1|refseq:NP_001275668.1|refseq:XP_005251825.1|refseq:XP_005251826.1|refseq:XP_016869860.1|dip:DIP-36242N|ensembl:ENSG00000106976(gene)|ensembl:ENST00000372923(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043196"(varicosity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1901998"(toxin transport)|go:"GO:1904645"(response to amyloid-beta)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR027741|interpro:IPR030381|mint:Q05193|rcsb pdb:1DYN|rcsb pdb:2DYN|rcsb pdb:2X2E|rcsb pdb:2X2F|rcsb pdb:3SNH|rcsb pdb:3ZYC|rcsb pdb:3ZYS|rcsb pdb:4UUD|rcsb pdb:4UUK|rcsb pdb:5D3Q|rcsb pdb:6DLU|rcsb pdb:6DLV|rcsb pdb:6S9A|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-437239|reactome:R-HSA-8856828|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ZSC3lfWt9Fx/FDRYJO3WbVWn4Bs9606	rogid:uiP8CXhKWQaP2GIAZULJTLqwGLs9606	intact-crc:48C45F530BF0C905|rigid:BfOicAzEO1+nC9mlSuSus162ZYg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IWF7	uniprotkb:P02792	intact:EBI-2340154	intact:EBI-713279|uniprotkb:Q7Z2W1|uniprotkb:Q9BTZ8|ensembl:ENSP00000366525|uniprotkb:B2R4B9|uniprotkb:Q6IBT7|uniprotkb:Q86WI9|uniprotkb:Q8WU07|uniprotkb:Q96AU9|uniprotkb:Q96CU0	psi-mi:u2d2l_human(display_long)|uniprotkb:UBE2DNL(gene name)|psi-mi:UBE2DNL(display_short)|uniprotkb:UBE2D2L(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2-like(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2-like(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2D N-terminal-like(gene name synonym)	psi-mi:fril_human(display_long)|uniprotkb:FTL(gene name)|psi-mi:FTL(display_short)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340160|imex:IM-11696-800	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)	refseq:NP_000137.2|ensembl:ENSG00000087086(gene)|ensembl:ENST00000331825(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0044754"(autolysosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|mint:P02792|rcsb pdb:2FFX|rcsb pdb:2FG4|rcsb pdb:2FG8|rcsb pdb:3KXU|rcsb pdb:4V6B|rcsb pdb:5LG8|rcsb pdb:6TR9|rcsb pdb:6TS0|rcsb pdb:6TS1|rcsb pdb:6TSA|rcsb pdb:6TSF|rcsb pdb:6TSJ|rcsb pdb:6WX6|reactome:R-HSA-3000480|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-917937|dip:DIP-31248N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ZSC3lfWt9Fx/FDRYJO3WbVWn4Bs9606	rogid:+mbnoETQ9TuBZg8Gc09nwAjwKTE9606	intact-crc:A58694F9D4D60E49|rigid:nEur8Bv6ZY60deKn2Aizq6zbl0A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P08865	uniprotkb:Q5VVX9	intact:EBI-354112|uniprotkb:Q6NSD1|uniprotkb:Q6NXQ8|uniprotkb:Q86VC0|uniprotkb:P11085|uniprotkb:P12030|uniprotkb:Q16471|uniprotkb:Q6IPD1|uniprotkb:Q6IPD2|ensembl:ENSP00000346067	intact:EBI-2130181|uniprotkb:Q8N1D4|intact:EBI-28974117|ensembl:ENSP00000481174	psi-mi:rssa_human(display_long)|uniprotkb:RPSA(gene name)|psi-mi:RPSA(display_short)|uniprotkb:LAMBR(gene name synonym)|uniprotkb:LAMR1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:Colon carcinoma laminin-binding protein(gene name synonym)|uniprotkb:NEM/1CHD4(gene name synonym)|uniprotkb:Multidrug resistance-associated protein MGr1-Ag(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS2(gene name synonym)	psi-mi:ube2u_human(display_long)|uniprotkb:UBE2U(gene name)|psi-mi:UBE2U(display_short)|uniprotkb:Ubiquitin-protein ligase U(gene name synonym)|uniprotkb:Ubiquitin carrier protein U(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme U(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340163|imex:IM-11696-801	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002286.2|refseq:NP_001291217.1|dip:DIP-32878N|ensembl:ENSG00000168028(gene)|ensembl:ENST00000301821(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0007155"(cell adhesion)|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZOJ|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0043236"(laminin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P08865|rcsb pdb:3BCH|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5	ensembl:ENST00000371076|ensembl:ENSP00000360116|ensembl:ENSP00000481174|refseq:NP_689702.1|ensembl:ENSG00000177414(gene)|ensembl:ENST00000611228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033503"(HULC complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YRV|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Jpv3I3G5C297fHfNwIqyB9Pf8/A9606	rogid:onw4DUslrZLhQZp8FtqY6s6Q/u09606	intact-crc:EE386A9759FE658C|rigid:UEEUvB/YoSIk87x2TZulSFwm5nU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IWF7	uniprotkb:O96000	intact:EBI-2340154	intact:EBI-1246371|uniprotkb:Q96II6|ensembl:ENSP00000268668	psi-mi:u2d2l_human(display_long)|uniprotkb:UBE2DNL(gene name)|psi-mi:UBE2DNL(display_short)|uniprotkb:UBE2D2L(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2-like(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2-like(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2D N-terminal-like(gene name synonym)	psi-mi:nduba_human(display_long)|uniprotkb:NDUFB10(gene name)|psi-mi:NDUFB10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase PDSW subunit(gene name synonym)|uniprotkb:Complex I-PDSW(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340166|imex:IM-11696-802	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)	refseq:NP_004539.1|ensembl:ENSG00000140990(gene)|ensembl:ENST00000268668(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|interpro:IPR019377|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039993|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|dip:DIP-38298N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ZSC3lfWt9Fx/FDRYJO3WbVWn4Bs9606	rogid:CRQJLj/I1jZSnIU7GeuRDGN4hRA9606	intact-crc:93DE6E58EC2AEB92|rigid:lm5GvM0zheol+dRekwjL2o/ij+0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IWF7	uniprotkb:O00303	intact:EBI-2340154	intact:EBI-711990|ensembl:ENSP00000431800|ensembl:ENSP00000499218|uniprotkb:Q6IB45|uniprotkb:Q8N978|uniprotkb:A8K0S2	psi-mi:u2d2l_human(display_long)|uniprotkb:UBE2DNL(gene name)|psi-mi:UBE2DNL(display_short)|uniprotkb:UBE2D2L(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2-like(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2-like(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2D N-terminal-like(gene name synonym)	psi-mi:eif3f_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 5(gene name synonym)|uniprotkb:eIF-3-epsilon(gene name synonym)|uniprotkb:eIF3 p47(gene name synonym)|uniprotkb:EIF3F(gene name)|psi-mi:EIF3F(display_short)|uniprotkb:EIF3S5(gene name synonym)|uniprotkb:Deubiquitinating enzyme eIF3f(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340172|imex:IM-11696-804	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)	ensembl:ENSG00000175390(gene)|ensembl:ENST00000533626(transcript)|ensembl:ENST00000651655(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR027531|interpro:IPR037518|mint:O00303|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_003745.1|dip:DIP-35580N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ZSC3lfWt9Fx/FDRYJO3WbVWn4Bs9606	rogid:dpH1pTcPshcrSjNCdPPnkYiW0YU9606	intact-crc:B7D43321C9F31262|rigid:NFB9JUK91H/FGaE/6d1qLBH/f14	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04183	uniprotkb:Q8IWF7	intact:EBI-712550|ensembl:ENSP00000301634|uniprotkb:Q969V0|uniprotkb:Q9UMG9|uniprotkb:B2RC58	intact:EBI-2340154	psi-mi:kith_human(display_long)|uniprotkb:TK1(gene name)|psi-mi:TK1(display_short)	psi-mi:u2d2l_human(display_long)|uniprotkb:UBE2DNL(gene name)|psi-mi:UBE2DNL(display_short)|uniprotkb:UBE2D2L(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2-like(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2-like(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2D N-terminal-like(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340169|imex:IM-11696-803	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167900(gene)|ensembl:ENST00000301634(transcript)|go:"GO:0004797"(thymidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046104"(thymidine metabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR001267(Thymidine kinase)|interpro:IPR020633|interpro:IPR027417|mint:P04183|rcsb pdb:1W4R|rcsb pdb:1XBT|rcsb pdb:2WVJ|reactome:R-HSA-69205|reactome:R-HSA-73614|rcsb pdb:2ORV|refseq:NP_003249.3	interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:OzSF0TaoKwVaTna3Cu3HcogkZUc9606	rogid:ZSC3lfWt9Fx/FDRYJO3WbVWn4Bs9606	intact-crc:3FD85988D646D574|rigid:Wimwqk2gcopYgrXlC/rSaB0vryg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BUK6	uniprotkb:Q8IWF7	intact:EBI-2340176|uniprotkb:Q7LBZ8|uniprotkb:Q5T717|uniprotkb:Q7Z3M7|uniprotkb:Q53GR8|uniprotkb:Q9NQX2|uniprotkb:Q9NVU4|uniprotkb:Q7Z558|uniprotkb:Q5CZ69|uniprotkb:Q8TE05|uniprotkb:Q68CT6|ensembl:ENSP00000245564	intact:EBI-2340154	psi-mi:msto1_human(display_long)|uniprotkb:MSTO1(gene name)|psi-mi:MSTO1(display_short)|uniprotkb:LST005(orf name)|uniprotkb:SLTP005(orf name)	psi-mi:u2d2l_human(display_long)|uniprotkb:UBE2DNL(gene name)|psi-mi:UBE2DNL(display_short)|uniprotkb:UBE2D2L(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2-like(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2-like(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2D N-terminal-like(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340175|imex:IM-11696-805	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508010.1|refseq:NP_060586.2|refseq:NP_001243461.1|refseq:NP_001243462.1|refseq:XP_016857098.1|ensembl:ENSG00000125459(gene)|ensembl:ENST00000245564(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0048311"(mitochondrion distribution)|interpro:IPR019605|interpro:IPR029209|interpro:IPR036525	interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:aZOmttCfkLs7GpgtF2DEp2gPrwQ9606	rogid:ZSC3lfWt9Fx/FDRYJO3WbVWn4Bs9606	intact-crc:157AFEFB843A8F9E|rigid:Zt9CBEnPi6107pevtIKcPXl3j0w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IWF7	uniprotkb:Q9NPB0	intact:EBI-2340154	intact:EBI-2340192|uniprotkb:Q9H0D8|ensembl:ENSP00000229903	psi-mi:u2d2l_human(display_long)|uniprotkb:UBE2DNL(gene name)|psi-mi:UBE2DNL(display_short)|uniprotkb:UBE2D2L(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2-like(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2-like(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2D N-terminal-like(gene name synonym)	psi-mi:smdc1_human(display_long)|uniprotkb:SAYSD1(gene name)|psi-mi:SAYSD1(display_short)|uniprotkb:C6orf64(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340197|imex:IM-11696-806	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)	refseq:NP_001291722.1|refseq:NP_060792.1|ensembl:ENSG00000112167(gene)|ensembl:ENST00000229903(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019387|interpro:IPR039159	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ZSC3lfWt9Fx/FDRYJO3WbVWn4Bs9606	rogid:F50jJQFdQCIC/llJt9kpcDRGqZM9606	intact-crc:F338011F84A6C51C|rigid:qgURf7ceNQvdtUjuBGSHXp/J/fg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IWF7	uniprotkb:Q9BQY4	intact:EBI-2340154	intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441	psi-mi:u2d2l_human(display_long)|uniprotkb:UBE2DNL(gene name)|psi-mi:UBE2DNL(display_short)|uniprotkb:UBE2D2L(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2-like(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2-like(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2D N-terminal-like(gene name synonym)	psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340200|imex:IM-11696-807	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)	refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ZSC3lfWt9Fx/FDRYJO3WbVWn4Bs9606	rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606	intact-crc:B47402144A21B55A|rigid:C5F5Upekwi69VjZYI4A4MbJL8to	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N1F8	uniprotkb:Q8IWF7	intact:EBI-2340204|uniprotkb:Q8NAW9|uniprotkb:Q96PY9|uniprotkb:Q8WXE4|uniprotkb:Q96CN3|uniprotkb:C9JQV3|ensembl:ENSP00000389383	intact:EBI-2340154	psi-mi:s11ip_human(display_long)|uniprotkb:STK11IP(gene name)|psi-mi:STK11IP(display_short)|uniprotkb:KIAA1898(gene name synonym)|uniprotkb:LIP1(gene name synonym)|uniprotkb:LKB1IP(gene name synonym)|uniprotkb:STK11IP1(gene name synonym)|uniprotkb:LKB1-interacting protein 1(gene name synonym)	psi-mi:u2d2l_human(display_long)|uniprotkb:UBE2DNL(gene name)|psi-mi:UBE2DNL(display_short)|uniprotkb:UBE2D2L(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2-like(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2-like(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2D N-terminal-like(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340203|imex:IM-11696-808	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_443134.3|ensembl:ENSG00000144589(gene)|ensembl:ENST00000456909(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0008104"(protein localization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035578"(azurophil granule lumen)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR031782|interpro:IPR032675|mint:Q8N1F8|reactome:R-HSA-6798695	interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2018/04/06	rogid:bkZvSPFpB2rsgtmUrzt1YPiGrp49606	rogid:ZSC3lfWt9Fx/FDRYJO3WbVWn4Bs9606	intact-crc:AB6E1190618CF3B0|rigid:KgqCWQaclrvhRFn4JpBDblP7eaA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:P14373	intact:EBI-2340216	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340215|imex:IM-11696-542	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:DC612BFBCC9A8C17|rigid:tw/JgLMOEES8aPNd9Tmu94659w4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99496	uniprotkb:B3KSH4	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480	intact:EBI-2340216	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340222|imex:IM-11696-331	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:1DF0F85AC1D6C772|rigid:SPdWK7ALVR6YufLlrBEvQIQjIWg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99942	uniprotkb:B3KSH4	intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3	intact:EBI-2340216	psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340225|imex:IM-11696-332	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:AA3AA155FA4D9076|rigid:40POgjqYwOrHDGm1BKGmv9giPpY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:Q8IUQ4	intact:EBI-2340216	intact:EBI-747107|uniprotkb:O43269|uniprotkb:Q49A58|uniprotkb:A0FKF3|uniprotkb:Q92880|ensembl:ENSP00000369343|ensembl:ENSP00000378214|ensembl:ENSP00000456421	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:siah1_human(display_long)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340228|imex:IM-11696-333	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:XP_006721309.1|refseq:NP_001006611.1|refseq:NP_003022.3|refseq:XP_011521581.1|ensembl:ENST00000380006(transcript)|ensembl:ENST00000394725(transcript)|ensembl:ENST00000568007(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|mint:Q8IUQ4|rcsb pdb:2A25|rcsb pdb:4C9Z|rcsb pdb:4CA1|rcsb pdb:4I7B|rcsb pdb:4I7C|rcsb pdb:4I7D|rcsb pdb:4X3G|rcsb pdb:5WZZ|reactome:R-HSA-373752|reactome:R-HSA-977225|reactome:R-HSA-983168|ensembl:ENSG00000196470(gene)|dip:DIP-35684N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:O6+z1g9K1ij87Xgo5/Ykl5Q3vUQ9606	intact-crc:8EF15D8B273709D3|rigid:R2lur95Jeud27sWGaUUpMY9qL5U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O94941	uniprotkb:B3KSH4	intact:EBI-751901|uniprotkb:Q6IAR5|uniprotkb:Q86X87|uniprotkb:Q9H4J2|ensembl:ENSP00000217173	intact:EBI-2340216	psi-mi:rnf37_human(display_long)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 5(gene name synonym)|uniprotkb:U-box domain-containing protein 5(gene name synonym)|uniprotkb:UBOX5(gene name)|psi-mi:UBOX5(display_short)|uniprotkb:KIAA0860(gene name synonym)|uniprotkb:RNF37(gene name synonym)|uniprotkb:UBCE7IP5(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF37(gene name synonym)|uniprotkb:UIP5(gene name synonym)|uniprotkb:UbcM4-interacting protein 5(gene name synonym)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340231|imex:IM-11696-334	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055763.1|refseq:NP_955447.1|ensembl:ENSG00000185019(gene)|ensembl:ENST00000217173(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039847|interpro:IPR039925|reactome:R-HSA-983168	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:bHUiSJ345KLIwL+xD2qH/CJVqL09606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:886A398622B89373|rigid:6XOQ/CaPDBzogI9DAkPvrCrT0e8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:Q9UPQ4	intact:EBI-2340216	intact:EBI-2130401|uniprotkb:Q86XQ0|uniprotkb:Q8WVA4|ensembl:ENSP00000301924	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:tri35_human(display_long)|uniprotkb:TRIM35(gene name)|psi-mi:TRIM35(display_short)|uniprotkb:HLS5(gene name synonym)|uniprotkb:KIAA1098(gene name synonym)|uniprotkb:Hemopoietic lineage switch protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340234|imex:IM-11696-335	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:NP_741983.2|ensembl:ENSG00000104228(gene)|ensembl:ENST00000305364(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR043136|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:VlC2XEURqN7nMIfIns2E0QVsL7k9606	intact-crc:EF61DF434F4E700E|rigid:LSKfZf16MRRMDk3hjJUdYpP5Mds	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NZS9	uniprotkb:B3KSH4	intact:EBI-2130199|uniprotkb:A8K4Z9|uniprotkb:D3DUG8|uniprotkb:B4DUT0|ensembl:ENSP00000261658|ensembl:ENSP00000478190	intact:EBI-2340216	psi-mi:bfar_human(display_long)|uniprotkb:BFAR(gene name)|psi-mi:BFAR(display_short)|uniprotkb:BAR(gene name synonym)|uniprotkb:RNF47(gene name synonym)|uniprotkb:RING finger protein 47(gene name synonym)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340237|imex:IM-11696-336	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057645.1|refseq:XP_005255407.1|ensembl:ENSG00000103429(gene)|ensembl:ENSG00000275618(gene)|ensembl:ENST00000261658(transcript)|ensembl:ENST00000619034(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017907	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:XDPFsRmdbch1NXffLOcE0lVrtRo9606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:6808AD716E5C042B|rigid:cDCCfu/dVxx/mDO/mJnL+dE+xSk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H992	uniprotkb:B3KSH4	intact:EBI-949983|ensembl:ENSP00000386830|ensembl:ENSP00000259050|uniprotkb:Q53GQ1|uniprotkb:Q9BTR9|uniprotkb:A8K9X1|uniprotkb:D3DPB0|uniprotkb:B7Z7P5	intact:EBI-2340216	psi-mi:marh7_human(display_long)|uniprotkb:MARCHF7(gene name)|psi-mi:MARCHF7(display_short)|uniprotkb:AXOT(gene name synonym)|uniprotkb:Axotrophin(gene name synonym)|uniprotkb:MARCH7(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 7(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein VII(gene name synonym)|uniprotkb:RING finger protein 177(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF7(gene name synonym)|uniprotkb:RNF177(gene name synonym)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340246|imex:IM-11696-543	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269734.1|refseq:NP_001269735.1|refseq:NP_001269736.1|ensembl:ENST00000259050(transcript)|ensembl:ENST00000409175(transcript)|go:"GO:0002643"(regulation of tolerance induction)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016740"(transferase activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050821"(protein stabilization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|ensembl:ENSG00000136536(gene)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_073737.1|refseq:XP_005246830.1	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:HT4KtjhOVdeP4mam5eQhgX+ib5A9606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:A2C63FA8EA615DD8|rigid:sA1ln8s37HkuAxzgUV+FRn3SD2Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:Q8WVD3	intact:EBI-2340216	intact:EBI-749039|uniprotkb:Q9H8K2|uniprotkb:Q9UF87|uniprotkb:Q9UKI6|uniprotkb:B2RE17|ensembl:ENSP00000261593	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:rn138_human(display_long)|uniprotkb:RING finger protein 138(gene name synonym)|uniprotkb:Nemo-like kinase-associated RING finger protein(gene name synonym)|uniprotkb:RNF138(gene name)|psi-mi:RNF138(display_short)|uniprotkb:NARF(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF138(gene name synonym)|uniprotkb:HSD-4(orf name)|uniprotkb:HSD4(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340240|imex:IM-11696-337	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:NP_057355.2|refseq:NP_937761.1|refseq:NP_001178253.2|refseq:XP_005258343.1|ensembl:ENSG00000134758(gene)|ensembl:ENST00000261593(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034734|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:HhGscRenFoqXTiZxHR62E4wcIo09606	intact-crc:209C89A46495D28A|rigid:tp63tMU3+9BETz5sFgOU8nf40n8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:Q96EQ8	intact:EBI-2340216	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340243|imex:IM-11696-338	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	intact-crc:C252C97F2EC8F53D|rigid:w+Hw5sr58zbbdeHr4AnDK9ZOwtY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:Q96GF1	intact:EBI-2340216	intact:EBI-2340249|uniprotkb:A8K5C1|uniprotkb:A9X3T8|uniprotkb:Q8N900|ensembl:ENSP00000320508|ensembl:ENSP00000427755	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:rn185_human(display_long)|uniprotkb:RNF185(gene name)|psi-mi:RNF185(display_short)|uniprotkb:RING finger protein 185(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF185(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340254|imex:IM-11696-544	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:NP_001129297.1|refseq:NP_689480.2|ensembl:ENSG00000138942(gene)|ensembl:ENST00000326132(transcript)|ensembl:ENST00000518626(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:ivzbt31KPTKL/Rc1Wzs3h80XJac9606	intact-crc:CC9106168EF1026D|rigid:Em2pQhXbVylUC0nwUPk13Cv5gWE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:Q8N9I9	intact:EBI-2340216	intact:EBI-2340258|uniprotkb:Q8NDS8|uniprotkb:Q8NAU6|uniprotkb:Q53ZZ2|ensembl:ENSP00000338050|ensembl:ENSP00000447873|ensembl:ENSP00000449294	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:dtx3_human(display_long)|uniprotkb:DTX3(gene name)|psi-mi:DTX3(display_short)|uniprotkb:RNF154(gene name synonym)|uniprotkb:RING finger protein 154(gene name synonym)|uniprotkb:Protein deltex-3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340257|imex:IM-11696-545	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:NP_001273174.1|refseq:NP_001273175.1|refseq:XP_011536324.1|refseq:NP_848597.1|refseq:XP_005268754.1|refseq:XP_005268755.1|refseq:XP_005268757.1|refseq:XP_005268760.1|ensembl:ENSG00000178498(gene)|ensembl:ENST00000337737(transcript)|ensembl:ENST00000548198(transcript)|ensembl:ENST00000548804(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:Ma7JBhgMdFofCeWESbf8h1iLAHY9606	intact-crc:282D4CC19B027902|rigid:8QNR+jAfrSDlc3uqlapSn9tMBHA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:P36406	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340266|imex:IM-11696-546	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	intact-crc:B4F99714693E8C6E|rigid:7yNZVWC0MEj7oMGso9lmJaG9Eg4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q13064	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-2340269|ensembl:ENSP00000313881	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340273|imex:IM-11696-339	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606	intact-crc:0F8EE6768F7472BE|rigid:N9y3t/E8iZLJkIIetsby/c4h1N0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86Y13	uniprotkb:Q99816	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340276|imex:IM-11696-340	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	intact-crc:4187AF0DC9885162|rigid:PtEUAxijhYarNygn9Nm5jibXNKI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H4P4	uniprotkb:Q99816	intact:EBI-2130266|uniprotkb:B2RBT8|uniprotkb:O75598|intact:EBI-2563208|intact:EBI-11576203|uniprotkb:A6NFW0|ensembl:ENSP00000342755|ensembl:ENSP00000447303|ensembl:ENSP00000484671	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	psi-mi:rnf41_human(display_long)|uniprotkb:RNF41(gene name)|psi-mi:RNF41(display_short)|uniprotkb:FLRF(gene name synonym)|uniprotkb:NRDP1(gene name synonym)|uniprotkb:RING finger protein 41(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NRDP1(gene name synonym)|uniprotkb:SBBI03(orf name)	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340279|imex:IM-11696-341	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011536036.1|refseq:XP_011536037.1|refseq:NP_001229755.1|refseq:NP_005776.1|refseq:NP_919340.1|refseq:NP_919339.1|refseq:XP_005268618.1|ensembl:ENSG00000181852(gene)|ensembl:ENST00000345093(transcript)|ensembl:ENST00000552656(transcript)|ensembl:ENST00000615206(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015036(USP8 interacting)|interpro:IPR017907|interpro:IPR037255|rcsb pdb:2FZP|rcsb pdb:2GWF|reactome:R-HSA-1358803|reactome:R-HSA-983168	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jthVZwxUECSdqeJ2jZQ5UL28kDY9606	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	intact-crc:0C92C4BAFF04C007|rigid:QAutocScka7+Cs66VgvumLoMeJU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q9BWF2	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-1756205|uniprotkb:O00467|uniprotkb:B5BU84|uniprotkb:B5BUL3|intact:EBI-28986477|ensembl:ENSP00000328203	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:traip_human(display_long)|uniprotkb:TRAIP(gene name)|psi-mi:TRAIP(display_short)|uniprotkb:RNF206(gene name synonym)|uniprotkb:TRIP(gene name synonym)|uniprotkb:RING finger protein 206(gene name synonym)|uniprotkb:TRAF-interacting protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340282|imex:IM-11696-342	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_005870.2|ensembl:ENSP00000328203|ensembl:ENSG00000183763(gene)|ensembl:ENST00000331456(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007165"(signal transduction)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090734"(site of DNA damage)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:4ZTD|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:af6osyzc1Cw/atmwUPTR1f5usBE9606	intact-crc:10FA5A62EC5C7A8B|rigid:8CybS347r/pycnmhKKNgtNfDoUY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q9UPQ4	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-2130401|uniprotkb:Q86XQ0|uniprotkb:Q8WVA4|ensembl:ENSP00000301924	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:tri35_human(display_long)|uniprotkb:TRIM35(gene name)|psi-mi:TRIM35(display_short)|uniprotkb:HLS5(gene name synonym)|uniprotkb:KIAA1098(gene name synonym)|uniprotkb:Hemopoietic lineage switch protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340285|imex:IM-11696-343	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_741983.2|ensembl:ENSG00000104228(gene)|ensembl:ENST00000305364(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR043136|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:VlC2XEURqN7nMIfIns2E0QVsL7k9606	intact-crc:305A4258C4724FE5|rigid:jn4MDmE1uwD2urizpkUVNQGelqQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:O60291	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-2129851|uniprotkb:A4URL3|uniprotkb:A4URL4|uniprotkb:Q86W76|intact:EBI-28986785|ensembl:ENSP00000382487	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:mgrn1_human(display_long)|uniprotkb:MGRN1(gene name)|psi-mi:MGRN1(display_short)|uniprotkb:KIAA0544(gene name synonym)|uniprotkb:RNF156(gene name synonym)|uniprotkb:Mahogunin RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 156(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MGRN1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340288|imex:IM-11696-344	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_001135761.2|refseq:NP_001135762.1|refseq:NP_001135763.2|refseq:NP_056061.1|ensembl:ENST00000262370|ensembl:ENSP00000262370|ensembl:ENSP00000382487|ensembl:ENST00000415496|ensembl:ENSP00000393311|ensembl:ENST00000586183|ensembl:ENSP00000465860|ensembl:ENST00000588994|ensembl:ENSP00000468819|refseq:XP_005255277.1|refseq:XP_005255278.1|ensembl:ENSG00000102858(gene)|ensembl:ENST00000399577(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:UuLoCnlkpTBs/rmGgpQvgiMNuNE9606	intact-crc:EF60452E3CB224A5|rigid:tzxfQFqolG3s/Q84IKC0qS+Wy9s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q9BV68	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-357322|ensembl:ENSP00000292363|uniprotkb:Q9NWX1|intact:EBI-11064977	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:rn126_human(display_long)|uniprotkb:RNF126(gene name)|psi-mi:RNF126(display_short)|uniprotkb:RING finger protein 126(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340291|imex:IM-11696-345	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	ensembl:ENSG00000070423(gene)|ensembl:ENST00000292363(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR039525|interpro:IPR039571|interpro:IPR039572|rcsb pdb:2N9O|rcsb pdb:2N9P|reactome:R-HSA-983168|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|refseq:NP_919442.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2019/01/23	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:4Z4AJGHJgoIUp9zhtfWcFBF1Fxw9606	intact-crc:9940D060E5AD9FF2|rigid:8KgyKkf1fO85rySrSOqyCHfTgGA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H270	uniprotkb:Q99816	intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6|ensembl:ENSP00000479680	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym)	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340294|imex:IM-11696-547	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068375.3|refseq:NP_001277114.1|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|ensembl:ENSG00000160695(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENST00000620429(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0007033"(vacuole organization)|go:"GO:0048284"(organelle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	intact-crc:8CEDF3E321EEA4BC|rigid:gmR/gGJ+FI9nLwV7aEARtyjHWwU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q6UWE0	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-720984|uniprotkb:Q5VVV0|uniprotkb:Q8NB40|uniprotkb:Q96GT5|uniprotkb:Q96MX5|uniprotkb:Q96MZ7|ensembl:ENSP00000300417|ensembl:ENSP00000322937|ensembl:ENSP00000362419|ensembl:ENSP00000502167	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:lrsm1_human(display_long)|uniprotkb:Leucine-rich repeat and sterile alpha motif-containing protein 1(gene name synonym)|uniprotkb:Tsg101-associated ligase(gene name synonym)|uniprotkb:LRSAM1(gene name)|psi-mi:LRSAM1(display_short)|uniprotkb:TAL(gene name synonym)|uniprotkb:UNQ6496/PRO21356(orf name)|uniprotkb:RING-type E3 ubiquitin transferase LRSAM1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340297|imex:IM-11696-548	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_001005373.1|refseq:NP_001005374.1|refseq:NP_001177652.1|refseq:NP_612370.3|refseq:XP_016870772.1|ensembl:ENSG00000148356(gene)|ensembl:ENST00000300417(transcript)|ensembl:ENST00000323301(transcript)|ensembl:ENST00000373322(transcript)|ensembl:ENST00000675448(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0046755"(viral budding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032675|mint:Q6UWE0|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:qkwPqOsfNjZBB2Xp6YAA9FbEZxM9606	intact-crc:FD28BBEC984724EF|rigid:W9sdWy2e+DHkSVch1EwqwhjCSJ4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63146	uniprotkb:Q9NS91	intact:EBI-712629|uniprotkb:P23567|uniprotkb:Q4PJ15|ensembl:ENSP00000265339|uniprotkb:Q9D0J6|uniprotkb:B2R503|uniprotkb:D3DQA2	intact:EBI-2339393|uniprotkb:Q9NRT6|uniprotkb:Q58F55|ensembl:ENSP00000264926	psi-mi:ube2b_human(display_long)|uniprotkb:Ubiquitin-protein ligase B(gene name synonym)|uniprotkb:Ubiquitin carrier protein B(gene name synonym)|uniprotkb:RAD6 homolog B(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa(gene name synonym)|uniprotkb:UBE2B(gene name)|psi-mi:UBE2B(display_short)|uniprotkb:RAD6B(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme B(gene name synonym)	psi-mi:rad18_human(display_long)|uniprotkb:RAD18(gene name)|psi-mi:RAD18(display_short)|uniprotkb:RNF73(gene name synonym)|uniprotkb:Postreplication repair protein RAD18(gene name synonym)|uniprotkb:RING finger protein 73(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RAD18(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340310|imex:IM-11696-551	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000119048(gene)|ensembl:ENST00000265339(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001741"(XY body)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0009411"(response to UV)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR023313|mint:P63146|rcsb pdb:1JAS|rcsb pdb:1NXA|rcsb pdb:2Y4W|rcsb pdb:2YB6|rcsb pdb:2YBF|reactome:R-HSA-110314|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0033503"(HULC complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0050821"(protein stabilization)|go:"GO:0051026"(chiasma assembly)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070076"(histone lysine demethylation)|go:"GO:0070193"(synaptonemal complex organization)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070829"(obsolete heterochromatin maintenance)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|refseq:NP_003328.1|dip:DIP-29832N	refseq:NP_064550.3|ensembl:ENSP00000264926|dip:DIP-29831N|ensembl:ENSG00000070950(gene)|ensembl:ENST00000264926(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097505"(Rad6-Rad18 complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036361|interpro:IPR039577|mint:Q9NS91|rcsb pdb:2MRE|rcsb pdb:2MRF|rcsb pdb:2Y43|rcsb pdb:2YBF|rcsb pdb:5VF0|reactome:R-HSA-110314|reactome:R-HSA-8866654|go:"GO:0060548"(negative regulation of cell death)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:JvcUPH+3qQXicPsIRFnW19NOc3c9606	rogid:/HmKCLqG1BxzmIWCgVpOw/gzJc49606	intact-crc:FE955E1C3221E406|rigid:JneWliiSgYIVdf1EuPV9Qcwujbo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q86UV6	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-2340301|uniprotkb:B7WP46|ensembl:ENSP00000285805	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:tri74_human(display_long)|uniprotkb:TRIM74(gene name)|psi-mi:TRIM74(display_short)|uniprotkb:TRIM50C(gene name synonym)|uniprotkb:Tripartite motif-containing protein 50C(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340300|imex:IM-11696-549	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:XP_011514489.1|refseq:XP_011514491.1|refseq:NP_942150.1|refseq:NP_001304744.1|ensembl:ENSG00000155428(gene)|ensembl:ENST00000285805(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:WsQRuhH8SQPPbtieNAA8PyDpwpE9606	intact-crc:2C1CC153E83E8B0A|rigid:DUqjAmSdDMpVT9v6KfJJtwklMYo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NS91	uniprotkb:P49459	intact:EBI-2339393|uniprotkb:Q9NRT6|uniprotkb:Q58F55|ensembl:ENSP00000264926	intact:EBI-2339348|uniprotkb:A6NMF5|uniprotkb:Q96FX4|uniprotkb:B2R7R9|uniprotkb:Q4TTG1|uniprotkb:D3DWI1|uniprotkb:A6NFE9|uniprotkb:A6NGR2|ensembl:ENSP00000360613	psi-mi:rad18_human(display_long)|uniprotkb:RAD18(gene name)|psi-mi:RAD18(display_short)|uniprotkb:RNF73(gene name synonym)|uniprotkb:Postreplication repair protein RAD18(gene name synonym)|uniprotkb:RING finger protein 73(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RAD18(gene name synonym)	psi-mi:ube2a_human(display_long)|uniprotkb:UBE2A(gene name)|psi-mi:UBE2A(display_short)|uniprotkb:RAD6A(gene name synonym)|uniprotkb:Ubiquitin-protein ligase A(gene name synonym)|uniprotkb:Ubiquitin carrier protein A(gene name synonym)|uniprotkb:RAD6 homolog A(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340307|imex:IM-11696-550	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064550.3|ensembl:ENSP00000264926|dip:DIP-29831N|ensembl:ENSG00000070950(gene)|ensembl:ENST00000264926(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097505"(Rad6-Rad18 complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036361|interpro:IPR039577|mint:Q9NS91|rcsb pdb:2MRE|rcsb pdb:2MRF|rcsb pdb:2Y43|rcsb pdb:2YBF|rcsb pdb:5VF0|reactome:R-HSA-110314|reactome:R-HSA-8866654|go:"GO:0060548"(negative regulation of cell death)	refseq:NP_003327.2|refseq:NP_861427.1|refseq:NP_001269090.1|dip:DIP-24260N|ensembl:ENSG00000077721(gene)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033503"(HULC complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P49459|rcsb pdb:6CYO|rcsb pdb:6CYR|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|ensembl:ENST00000371558(transcript)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:/HmKCLqG1BxzmIWCgVpOw/gzJc49606	rogid:T6Mzgy6RHO9HoEIG3FmQvsP32vU9606	intact-crc:6EFA7D83091EB3ED|rigid:vHk9Q6R6zH2fGNsnhXEr3qEbCio	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:P98170	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340313|imex:IM-11696-552	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	intact-crc:02DB0A062397083D|rigid:5eZRZPj/O/2HT1a8GJTN4KSK50U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:O15344	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-2340316|uniprotkb:Q9BZX5|uniprotkb:O75361|uniprotkb:B2RCG2|ensembl:ENSP00000312678|ensembl:ENSP00000370156|ensembl:ENSP00000370157|ensembl:ENSP00000370162|ensembl:ENSP00000370164|ensembl:ENSP00000414521	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:tri18_human(display_long)|uniprotkb:MID1(gene name)|psi-mi:MID1(display_short)|uniprotkb:FXY(gene name synonym)|uniprotkb:RNF59(gene name synonym)|uniprotkb:TRIM18(gene name synonym)|uniprotkb:XPRF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 18(gene name synonym)|uniprotkb:Putative transcription factor XPRF(gene name synonym)|uniprotkb:Midin(gene name synonym)|uniprotkb:RING finger protein 59(gene name synonym)|uniprotkb:RING finger protein Midline-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Midline-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340322|imex:IM-11696-553	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_000372.1|refseq:NP_001092094.1|refseq:NP_001180206.1|refseq:NP_001180207.1|refseq:NP_001180208.1|refseq:NP_001180209.1|refseq:NP_001180210.1|refseq:NP_150632.1|refseq:NP_001334662.1|refseq:XP_016885025.1|refseq:XP_016885029.1|ensembl:ENSG00000101871(gene)|ensembl:ENST00000317552(transcript)|ensembl:ENST00000380779(transcript)|ensembl:ENST00000380780(transcript)|ensembl:ENST00000380785(transcript)|ensembl:ENST00000380787(transcript)|ensembl:ENST00000453318(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016740"(transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003649(B-box, C-terminal)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR027727|interpro:IPR036116|interpro:IPR040859|interpro:IPR043136|rcsb pdb:2DQ5|rcsb pdb:2FFW|rcsb pdb:2JUN|rcsb pdb:5IM8|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:NGlMGyFT7GEcrzVR/Iw4LitMBig9606	intact-crc:59E88D4B90B38BAF|rigid:9WFZTL23p1N+K8N/qoNqBWIUrsQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:P14373	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340325|imex:IM-11696-554	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:C5993F1A00B34D0B|rigid:1wCFyRfwbqELzmNvcsTKngAp1Qw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99496	uniprotkb:P51668	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340328|imex:IM-11696-555	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:6FBD8E3B8F8170E4|rigid:0ZezsMuo0NykDxas5YtW+jLOGdk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q99942	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340331|imex:IM-11696-556	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606	intact-crc:D877D734B41A27E0|rigid:W7aaS1hnk5Hne0awqmX0QWngC9w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q13064	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-2340269|ensembl:ENSP00000313881	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340334|imex:IM-11696-116	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606	intact-crc:75991DABC4CD84A9|rigid:ehNPfv3/qNGCvaZM7uphxSPzg8w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q9UBS8	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-2130308|uniprotkb:B7ZLV2|uniprotkb:A0AV26|uniprotkb:A6NMR2|uniprotkb:B3KN72|uniprotkb:O94793|uniprotkb:Q6IBV0|uniprotkb:A8MTW5|uniprotkb:D3DQE4|ensembl:ENSP00000324956|ensembl:ENSP00000348462|ensembl:ENSP00000378027|ensembl:ENSP00000378028	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:rnf14_human(display_long)|uniprotkb:RNF14(gene name)|psi-mi:RNF14(display_short)|uniprotkb:ARA54(gene name synonym)|uniprotkb:RING finger protein 14(gene name synonym)|uniprotkb:Androgen receptor-associated protein 54(gene name synonym)|uniprotkb:Triad2 protein(gene name synonym)|uniprotkb:HFB30(gene name synonym)|uniprotkb:HRIHFB2038(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340337|imex:IM-11696-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:XP_011536016.1|refseq:NP_001188294.1|refseq:NP_004281.1|refseq:NP_899645.1|refseq:NP_899646.1|refseq:NP_899647.1|refseq:NP_899648.1|refseq:XP_016865559.1|refseq:XP_016865560.1|refseq:XP_016865561.1|refseq:XP_005268593.1|refseq:XP_005268594.1|refseq:XP_005268596.1|refseq:XP_005268597.1|refseq:XP_005268598.1|ensembl:ENSG00000013561(gene)|ensembl:ENST00000347642(transcript)|ensembl:ENST00000356143(transcript)|ensembl:ENST00000394519(transcript)|ensembl:ENST00000394520(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017907|interpro:IPR031127|interpro:IPR031128|interpro:IPR044066|mint:Q9UBS8|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:zCNZ6kHw7XNUvpVBRQSgZ7ffJ9U9606	intact-crc:1D263ADE69CA63DB|rigid:R7ERwMq4mVCt7WSJde+R0sgQeHA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q86Y13	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340340|imex:IM-11696-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:B6061EC03A89D5B0|rigid:FZKFQG367D3xzzo9gFQRbTZAnSM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O94941	uniprotkb:P51668	intact:EBI-751901|uniprotkb:Q6IAR5|uniprotkb:Q86X87|uniprotkb:Q9H4J2|ensembl:ENSP00000217173	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:rnf37_human(display_long)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 5(gene name synonym)|uniprotkb:U-box domain-containing protein 5(gene name synonym)|uniprotkb:UBOX5(gene name)|psi-mi:UBOX5(display_short)|uniprotkb:KIAA0860(gene name synonym)|uniprotkb:RNF37(gene name synonym)|uniprotkb:UBCE7IP5(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF37(gene name synonym)|uniprotkb:UIP5(gene name synonym)|uniprotkb:UbcM4-interacting protein 5(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340346|imex:IM-11696-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055763.1|refseq:NP_955447.1|ensembl:ENSG00000185019(gene)|ensembl:ENST00000217173(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039847|interpro:IPR039925|reactome:R-HSA-983168	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:bHUiSJ345KLIwL+xD2qH/CJVqL09606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:9708FA3468FA6F09|rigid:Fb1mVb9yY/p2MoooMUgGWi9L/G4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y3C5	uniprotkb:P51668	intact:EBI-396669|intact:EBI-2129167|uniprotkb:A8KAI2|uniprotkb:Q5T7R8|ensembl:ENSP00000242719	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:rnf11_human(display_long)|uniprotkb:CGI-123(orf name)|uniprotkb:RNF11(gene name)|psi-mi:RNF11(display_short)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340349|imex:IM-11696-346	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055187.1|ensembl:ENSP00000242719|ensembl:ENSG00000123091(gene)|ensembl:ENST00000242719(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042981|mint:Q9Y3C5	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Uj0YAf/t+AdYbMd6fgQ8hVKoP0w9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:DC4D7EF483F9F6BB|rigid:8KJCHvUBv0bUNe/fIMo7U/wdU/4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q8N5U6	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-714023|uniprotkb:Q92550|uniprotkb:Q9NPP8|uniprotkb:Q9ULW4|ensembl:ENSP00000322242	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:rnf10_human(display_long)|uniprotkb:RNF10(gene name)|psi-mi:RNF10(display_short)|uniprotkb:KIAA0262(gene name synonym)|uniprotkb:RIE2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340343|imex:IM-11696-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_055683.3|refseq:NP_001317403.1|ensembl:ENSG00000022840(gene)|ensembl:ENST00000325954(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039739|mint:Q8N5U6	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:Bca0Ae456x1eCsdlduoCbn7coUQ9606	intact-crc:17A4784E53C2F347|rigid:6zZqkRcqLPKYe4omOrsJ95F/i38	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6ZNA4	uniprotkb:P51668	intact:EBI-2129175|uniprotkb:Q6ZMU2|uniprotkb:Q7L428|uniprotkb:Q7Z346|uniprotkb:Q8N1P9|uniprotkb:Q8WUA3|uniprotkb:Q9NSR1|uniprotkb:Q6P9A4|uniprotkb:C9JUS4|uniprotkb:H0YN55|ensembl:ENSP00000452732|intact:EBI-28970158	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:rn111_human(display_long)|uniprotkb:RNF111(gene name)|psi-mi:RNF111(display_short)|uniprotkb:RING finger protein 111(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Arkadia(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340352|imex:IM-11696-347	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060080.6|ensembl:ENST00000348370|ensembl:ENSP00000288199|ensembl:ENSP00000452732|ensembl:ENST00000559209|ensembl:ENSP00000453872|ensembl:ENST00000561186|ensembl:ENSP00000453015|refseq:NP_001317260.1|refseq:XP_016877827.1|refseq:XP_006720642.1|refseq:NP_001257459.1|refseq:NP_001257457.1|refseq:NP_001257458.1|ensembl:ENSG00000157450(gene)|ensembl:ENST00000557998(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR029306|rcsb pdb:2KIZ|rcsb pdb:5LG0|rcsb pdb:5LG7|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-5696395|reactome:R-HSA-983168|go:"GO:0032184"(SUMO polymer binding)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:6SY5oMr5u4mnVi+zdRboVljMGa09606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:CD7CF48B882CFA18|rigid:9wpDQqwGe9h8ZUZEAjGrnDlzhQY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q96EQ8	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340355|imex:IM-11696-348	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	intact-crc:B01FBF1E609F42AB|rigid:1IqqPGlryOWWBw3EOh3Qd7LfgNI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BV68	uniprotkb:P51668	intact:EBI-357322|ensembl:ENSP00000292363|uniprotkb:Q9NWX1|intact:EBI-11064977	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:rn126_human(display_long)|uniprotkb:RNF126(gene name)|psi-mi:RNF126(display_short)|uniprotkb:RING finger protein 126(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340358|imex:IM-11696-349	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000070423(gene)|ensembl:ENST00000292363(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR039525|interpro:IPR039571|interpro:IPR039572|rcsb pdb:2N9O|rcsb pdb:2N9P|reactome:R-HSA-983168|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|refseq:NP_919442.1	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2019/01/23	rogid:4Z4AJGHJgoIUp9zhtfWcFBF1Fxw9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:34363B1A20C6178F|rigid:ef4eBaijjMttLFIQgQuuTaDJLj0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q9Y508	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-723587|uniprotkb:Q6N0B0|uniprotkb:B2RDQ9|uniprotkb:B4DWY5|uniprotkb:E1P627|ensembl:ENSP00000244061	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:rn114_human(display_long)|uniprotkb:Zinc finger protein 313(gene name synonym)|uniprotkb:RNF114(gene name)|psi-mi:RNF114(display_short)|uniprotkb:ZNF313(gene name synonym)|uniprotkb:ZNF228(gene name synonym)|uniprotkb:Zinc finger protein 228(gene name synonym)|uniprotkb:RING finger protein 114(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF114(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340361|imex:IM-11696-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_061153.1|ensembl:ENSG00000124226(gene)|ensembl:ENST00000244061(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR034734|interpro:IPR042716|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:R1fX8xaGuIhy/M6cLzPeyfJBf649606	intact-crc:A826F7194A5B2828|rigid:PI4P7dkol/4k30yef99KGIKfeN8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q9HCM9	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-739510|uniprotkb:Q5STG4|uniprotkb:Q76BL3|uniprotkb:Q8IYT9|uniprotkb:Q96IB6|ensembl:ENSP00000365844|ensembl:ENSP00000373096|ensembl:ENSP00000379796|ensembl:ENSP00000391917|ensembl:ENSP00000397043|ensembl:ENSP00000398355|ensembl:ENSP00000409902|ensembl:ENSP00000411949|ensembl:ENSP00000447835|ensembl:ENSP00000448462|ensembl:ENSP00000448572|ensembl:ENSP00000449272|ensembl:ENSP00000449847|ensembl:ENSP00000450288|uniprotkb:Q5STG3	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:tri39_human(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340364|imex:IM-11696-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376656(transcript)|ensembl:ENST00000383602(transcript)|ensembl:ENST00000396547(transcript)|ensembl:ENST00000413715(transcript)|ensembl:ENST00000424575(transcript)|ensembl:ENST00000445206(transcript)|ensembl:ENST00000426469(transcript)|ensembl:ENST00000451715(transcript)|ensembl:ENST00000547030(transcript)|ensembl:ENST00000548002(transcript)|ensembl:ENST00000549841(transcript)|ensembl:ENST00000550282(transcript)|ensembl:ENST00000552337(transcript)|ensembl:ENST00000552520(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035033|interpro:IPR043136|mint:Q9HCM9|rcsb pdb:2DID|rcsb pdb:2DIF|rcsb pdb:2ECJ|reactome:R-HSA-983168|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_067076.2|refseq:NP_742013.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:xMCXGcMTqCjzLQzC53o81S4gqZA9606	intact-crc:8502CF51CEBA5783|rigid:VoiC0qYKCiP3O3m+B5V9/t0AAQM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q96BH1	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-2129220|uniprotkb:A8K0D6|uniprotkb:Q9H874|uniprotkb:Q53HQ5|ensembl:ENSP00000295704	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:rnf25_human(display_long)|uniprotkb:RNF25(gene name)|psi-mi:RNF25(display_short)|uniprotkb:RING finger protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF25(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340367|imex:IM-11696-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_071898.2|dip:DIP-29063N|ensembl:ENSG00000163481(gene)|ensembl:ENST00000295704(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR039133|rcsb pdb:2DAY|rcsb pdb:2DMF|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:YyCN7mH4eng9G05zRci49oJzKO09606	intact-crc:AD69B6810562E204|rigid:9+WleYPUQGx00BPv8iuRY9XPPw8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q96GF1	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-2340249|uniprotkb:A8K5C1|uniprotkb:A9X3T8|uniprotkb:Q8N900|ensembl:ENSP00000320508|ensembl:ENSP00000427755	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:rn185_human(display_long)|uniprotkb:RNF185(gene name)|psi-mi:RNF185(display_short)|uniprotkb:RING finger protein 185(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF185(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340382|imex:IM-11696-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_001129297.1|refseq:NP_689480.2|ensembl:ENSG00000138942(gene)|ensembl:ENST00000326132(transcript)|ensembl:ENST00000518626(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:ivzbt31KPTKL/Rc1Wzs3h80XJac9606	intact-crc:BEDC7077C0A6B5FB|rigid:/w8LW19QuMLJJ6vsExP9LplVaWw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZR9	uniprotkb:P51668	intact:EBI-2340370|uniprotkb:Q9C028|uniprotkb:A6NI31|intact:EBI-2796718|ensembl:ENSP00000496301	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:trim8_human(display_long)|uniprotkb:Tripartite motif-containing protein 8(gene name synonym)|uniprotkb:TRIM8(gene name)|psi-mi:TRIM8(display_short)|uniprotkb:GERP(gene name synonym)|uniprotkb:RNF27(gene name synonym)|uniprotkb:RING finger protein 27(gene name synonym)|uniprotkb:Glioblastoma-expressed RING finger protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM8(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340376|imex:IM-11696-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112174.2|ensembl:ENSG00000171206(gene)|ensembl:ENST00000643721(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0016740"(transferase activity)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902187"|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-877300	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:WFqavXVFV3/XbJSA2k06Pg9Eaag9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:1611783B47E8E8C2|rigid:gjLHkpFS/aaPJlTggvsOXnVWmRo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q8ND25	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340379|imex:IM-11696-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	intact-crc:D1B87824FF4FFB8C|rigid:PJ3OdNj18WEVNReY3L2/OaMKAkw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96A37	uniprotkb:P51668	intact:EBI-2130320|uniprotkb:B3KQ03|uniprotkb:Q96DM0|uniprotkb:D3DX75|uniprotkb:H3BTU8|ensembl:ENSP00000326095	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:rn166_human(display_long)|uniprotkb:RNF166(gene name)|psi-mi:RNF166(display_short)|uniprotkb:RING finger protein 166(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF166(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340385|imex:IM-11696-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001165286.1|refseq:NP_001165287.1|refseq:NP_849163.1|refseq:XP_016878402.1|ensembl:ENSG00000158717(gene)|ensembl:ENST00000312838(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:QV195sbjVofHePvnO8nsleiWSkg9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:13C33B837ED7A8EA|rigid:knlhx9LfQOHmQV3RT9P1619wnpM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q96BQ3	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-2129899|uniprotkb:Q53TJ7|ensembl:ENSP00000272395	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:tri43_human(display_long)|uniprotkb:TRIM43(gene name)|psi-mi:TRIM43(display_short)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340388|imex:IM-11696-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_620155.1|ensembl:ENSG00000144015(gene)|ensembl:ENST00000272395(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0045087"(innate immune response)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR043136	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:pfo60amX0NFspl9zqQ/Cgek6yO09606	intact-crc:91E97E8D854E2AB4|rigid:1xNakRN8kEsdZOWdAUhhgnGN238	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:P98170	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340402|imex:IM-11696-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	intact-crc:ADE7E612E020980C|rigid:10Ir6LnSgk/UcwH8Sn46RYoNIwk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TDB6	uniprotkb:P51668	intact:EBI-2340392|uniprotkb:Q5MJP7|uniprotkb:Q53ZZ3|uniprotkb:B3KWH6|ensembl:ENSP00000296161	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:dtx3l_human(display_long)|uniprotkb:DTX3L(gene name)|psi-mi:DTX3L(display_short)|uniprotkb:BBAP(gene name synonym)|uniprotkb:B-lymphoma- and BAL-associated protein(gene name synonym)|uniprotkb:Rhysin-2(gene name synonym)|uniprotkb:Protein deltex-3-like(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3L(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340391|imex:IM-11696-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612144.1|ensembl:ENSG00000163840(gene)|ensembl:ENST00000296161(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0015031"(protein transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:2000646"(positive regulation of receptor catabolic process)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|interpro:IPR042843|rcsb pdb:3PG6|reactome:R-HSA-983168	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:d2ctDfd7pj1wRA3HxmyWJ5nL19Y9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:9D33F4D765A820ED|rigid:HRjrb0OuXZTKoUS5ovvKy7k/NN8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q8N9I9	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-2340258|uniprotkb:Q8NDS8|uniprotkb:Q8NAU6|uniprotkb:Q53ZZ2|ensembl:ENSP00000338050|ensembl:ENSP00000447873|ensembl:ENSP00000449294	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:dtx3_human(display_long)|uniprotkb:DTX3(gene name)|psi-mi:DTX3(display_short)|uniprotkb:RNF154(gene name synonym)|uniprotkb:RING finger protein 154(gene name synonym)|uniprotkb:Protein deltex-3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340399|imex:IM-11696-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_001273174.1|refseq:NP_001273175.1|refseq:XP_011536324.1|refseq:NP_848597.1|refseq:XP_005268754.1|refseq:XP_005268755.1|refseq:XP_005268757.1|refseq:XP_005268760.1|ensembl:ENSG00000178498(gene)|ensembl:ENST00000337737(transcript)|ensembl:ENST00000548198(transcript)|ensembl:ENST00000548804(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:Ma7JBhgMdFofCeWESbf8h1iLAHY9606	intact-crc:5A603AA0D555CE94|rigid:a2zJdiIESlD0HtdrhotNYKPfw9Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:O15344	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-2340316|uniprotkb:Q9BZX5|uniprotkb:O75361|uniprotkb:B2RCG2|ensembl:ENSP00000312678|ensembl:ENSP00000370156|ensembl:ENSP00000370157|ensembl:ENSP00000370162|ensembl:ENSP00000370164|ensembl:ENSP00000414521	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:tri18_human(display_long)|uniprotkb:MID1(gene name)|psi-mi:MID1(display_short)|uniprotkb:FXY(gene name synonym)|uniprotkb:RNF59(gene name synonym)|uniprotkb:TRIM18(gene name synonym)|uniprotkb:XPRF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 18(gene name synonym)|uniprotkb:Putative transcription factor XPRF(gene name synonym)|uniprotkb:Midin(gene name synonym)|uniprotkb:RING finger protein 59(gene name synonym)|uniprotkb:RING finger protein Midline-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Midline-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340405|imex:IM-11696-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_000372.1|refseq:NP_001092094.1|refseq:NP_001180206.1|refseq:NP_001180207.1|refseq:NP_001180208.1|refseq:NP_001180209.1|refseq:NP_001180210.1|refseq:NP_150632.1|refseq:NP_001334662.1|refseq:XP_016885025.1|refseq:XP_016885029.1|ensembl:ENSG00000101871(gene)|ensembl:ENST00000317552(transcript)|ensembl:ENST00000380779(transcript)|ensembl:ENST00000380780(transcript)|ensembl:ENST00000380785(transcript)|ensembl:ENST00000380787(transcript)|ensembl:ENST00000453318(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016740"(transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003649(B-box, C-terminal)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR027727|interpro:IPR036116|interpro:IPR040859|interpro:IPR043136|rcsb pdb:2DQ5|rcsb pdb:2FFW|rcsb pdb:2JUN|rcsb pdb:5IM8|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:NGlMGyFT7GEcrzVR/Iw4LitMBig9606	intact-crc:93A6C104313236DE|rigid:i+iYbQ+/xQih57Rxo7GpB/JEawc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:P14373	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340408|imex:IM-11696-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:0FD77355A132F07A|rigid:CDig31d7tFREcNsSjCuPXKWUvFA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99942	uniprotkb:P62837	intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340417|imex:IM-11696-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:774B3B2077ADB7D1|rigid:UaeMH3s9KJnX68kqAx349kuPmTI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06587	uniprotkb:P62837	intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340411|imex:IM-11696-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:E086159201C7075A|rigid:2ByyD62TlgjRmRa3t1PtjakuUEI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99496	uniprotkb:P62837	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340414|imex:IM-11696-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:C081622F4C36E0D5|rigid:hLY1bkN0qKt5nS5i4KPhDjEGPbw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q13064	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-2340269|ensembl:ENSP00000313881	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340420|imex:IM-11696-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606	intact-crc:DAA5F1BF077A1498|rigid:P+4P/F7gwYLKo+41aJRgCjvED24	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q9UBS8	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-2130308|uniprotkb:B7ZLV2|uniprotkb:A0AV26|uniprotkb:A6NMR2|uniprotkb:B3KN72|uniprotkb:O94793|uniprotkb:Q6IBV0|uniprotkb:A8MTW5|uniprotkb:D3DQE4|ensembl:ENSP00000324956|ensembl:ENSP00000348462|ensembl:ENSP00000378027|ensembl:ENSP00000378028	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:rnf14_human(display_long)|uniprotkb:RNF14(gene name)|psi-mi:RNF14(display_short)|uniprotkb:ARA54(gene name synonym)|uniprotkb:RING finger protein 14(gene name synonym)|uniprotkb:Androgen receptor-associated protein 54(gene name synonym)|uniprotkb:Triad2 protein(gene name synonym)|uniprotkb:HFB30(gene name synonym)|uniprotkb:HRIHFB2038(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340423|imex:IM-11696-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:XP_011536016.1|refseq:NP_001188294.1|refseq:NP_004281.1|refseq:NP_899645.1|refseq:NP_899646.1|refseq:NP_899647.1|refseq:NP_899648.1|refseq:XP_016865559.1|refseq:XP_016865560.1|refseq:XP_016865561.1|refseq:XP_005268593.1|refseq:XP_005268594.1|refseq:XP_005268596.1|refseq:XP_005268597.1|refseq:XP_005268598.1|ensembl:ENSG00000013561(gene)|ensembl:ENST00000347642(transcript)|ensembl:ENST00000356143(transcript)|ensembl:ENST00000394519(transcript)|ensembl:ENST00000394520(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017907|interpro:IPR031127|interpro:IPR031128|interpro:IPR044066|mint:Q9UBS8|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:zCNZ6kHw7XNUvpVBRQSgZ7ffJ9U9606	intact-crc:B21AD6CAAA7DF3EA|rigid:qS3urReOd6kPgpege/8yM1gfzaI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5U6	uniprotkb:P62837	intact:EBI-714023|uniprotkb:Q92550|uniprotkb:Q9NPP8|uniprotkb:Q9ULW4|ensembl:ENSP00000322242	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:rnf10_human(display_long)|uniprotkb:RNF10(gene name)|psi-mi:RNF10(display_short)|uniprotkb:KIAA0262(gene name synonym)|uniprotkb:RIE2(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340429|imex:IM-11696-350	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055683.3|refseq:NP_001317403.1|ensembl:ENSG00000022840(gene)|ensembl:ENST00000325954(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039739|mint:Q8N5U6	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Bca0Ae456x1eCsdlduoCbn7coUQ9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:B898945A90756376|rigid:aDBx9duImS0/NTdp7UOJK8mC168	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q86Y13	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340426|imex:IM-11696-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:193AF2D4F93E4581|rigid:2o0YaHFmbO7gla/Q9LykdYsuLYA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:O94941	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-751901|uniprotkb:Q6IAR5|uniprotkb:Q86X87|uniprotkb:Q9H4J2|ensembl:ENSP00000217173	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:rnf37_human(display_long)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 5(gene name synonym)|uniprotkb:U-box domain-containing protein 5(gene name synonym)|uniprotkb:UBOX5(gene name)|psi-mi:UBOX5(display_short)|uniprotkb:KIAA0860(gene name synonym)|uniprotkb:RNF37(gene name synonym)|uniprotkb:UBCE7IP5(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF37(gene name synonym)|uniprotkb:UIP5(gene name synonym)|uniprotkb:UbcM4-interacting protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340432|imex:IM-11696-351	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_055763.1|refseq:NP_955447.1|ensembl:ENSG00000185019(gene)|ensembl:ENST00000217173(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039847|interpro:IPR039925|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:bHUiSJ345KLIwL+xD2qH/CJVqL09606	intact-crc:5D46B67BC97BD278|rigid:7x6wcPy1RIqnJx72f235J6YbsYk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q9Y3C5	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-396669|intact:EBI-2129167|uniprotkb:A8KAI2|uniprotkb:Q5T7R8|ensembl:ENSP00000242719	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:rnf11_human(display_long)|uniprotkb:CGI-123(orf name)|uniprotkb:RNF11(gene name)|psi-mi:RNF11(display_short)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340435|imex:IM-11696-352	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_055187.1|ensembl:ENSP00000242719|ensembl:ENSG00000123091(gene)|ensembl:ENST00000242719(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042981|mint:Q9Y3C5	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:Uj0YAf/t+AdYbMd6fgQ8hVKoP0w9606	intact-crc:737192E0404E668A|rigid:RDLiR+M2V+bH5mdKpAzKPr37IWQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6ZNA4	uniprotkb:P62837	intact:EBI-2129175|uniprotkb:Q6ZMU2|uniprotkb:Q7L428|uniprotkb:Q7Z346|uniprotkb:Q8N1P9|uniprotkb:Q8WUA3|uniprotkb:Q9NSR1|uniprotkb:Q6P9A4|uniprotkb:C9JUS4|uniprotkb:H0YN55|ensembl:ENSP00000452732|intact:EBI-28970158	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:rn111_human(display_long)|uniprotkb:RNF111(gene name)|psi-mi:RNF111(display_short)|uniprotkb:RING finger protein 111(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Arkadia(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340438|imex:IM-11696-353	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060080.6|ensembl:ENST00000348370|ensembl:ENSP00000288199|ensembl:ENSP00000452732|ensembl:ENST00000559209|ensembl:ENSP00000453872|ensembl:ENST00000561186|ensembl:ENSP00000453015|refseq:NP_001317260.1|refseq:XP_016877827.1|refseq:XP_006720642.1|refseq:NP_001257459.1|refseq:NP_001257457.1|refseq:NP_001257458.1|ensembl:ENSG00000157450(gene)|ensembl:ENST00000557998(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR029306|rcsb pdb:2KIZ|rcsb pdb:5LG0|rcsb pdb:5LG7|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-5696395|reactome:R-HSA-983168|go:"GO:0032184"(SUMO polymer binding)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:6SY5oMr5u4mnVi+zdRboVljMGa09606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:6240189F4B9B6A29|rigid:tp9Y394G9m8zhKIsegtyFGDqBQM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q96EQ8	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340441|imex:IM-11696-354	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	intact-crc:1F23530AA328D29A|rigid:AkyEG+fZ0Xz+iLv8XZuvZ5YHDvE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y508	uniprotkb:P62837	intact:EBI-723587|uniprotkb:Q6N0B0|uniprotkb:B2RDQ9|uniprotkb:B4DWY5|uniprotkb:E1P627|ensembl:ENSP00000244061	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:rn114_human(display_long)|uniprotkb:Zinc finger protein 313(gene name synonym)|uniprotkb:RNF114(gene name)|psi-mi:RNF114(display_short)|uniprotkb:ZNF313(gene name synonym)|uniprotkb:ZNF228(gene name synonym)|uniprotkb:Zinc finger protein 228(gene name synonym)|uniprotkb:RING finger protein 114(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF114(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340450|imex:IM-11696-357	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061153.1|ensembl:ENSG00000124226(gene)|ensembl:ENST00000244061(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR034734|interpro:IPR042716|reactome:R-HSA-983168	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:R1fX8xaGuIhy/M6cLzPeyfJBf649606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:071A1B0D89ECB819|rigid:7enwrr3ua8masa6sRDonNzyJxj4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6PCD5	uniprotkb:P62837	intact:EBI-2129159|uniprotkb:Q9H9Q3|uniprotkb:Q9NVT4|uniprotkb:Q5XKR3|uniprotkb:A8K585|uniprotkb:B2RE35|uniprotkb:D3DUJ8|ensembl:ENSP00000354361|ensembl:ENSP00000460049	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:rfwd3_human(display_long)|uniprotkb:RFWD3(gene name)|psi-mi:RFWD3(display_short)|uniprotkb:RING finger and WD repeat domain-containing protein 3(gene name synonym)|uniprotkb:RNF201(gene name synonym)|uniprotkb:RING finger protein 201(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340444|imex:IM-11696-355	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011521493.1|refseq:NP_060594.3|refseq:XP_016878880.1|refseq:XP_005256078.1|refseq:XP_005256079.1|dip:DIP-52688N|ensembl:ENSG00000168411(gene)|ensembl:ENST00000361070(transcript)|ensembl:ENST00000571750(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031297"(replication fork processing)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037381|rcsb pdb:6CVZ	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:r7gkMbkS0GKPVn9riLPR34KFaKk9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:DCD62BAD8739F00C|rigid:VKfrwNL1AHpa/9tZdSw9qdPCWgU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q9BV68	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-357322|ensembl:ENSP00000292363|uniprotkb:Q9NWX1|intact:EBI-11064977	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:rn126_human(display_long)|uniprotkb:RNF126(gene name)|psi-mi:RNF126(display_short)|uniprotkb:RING finger protein 126(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340447|imex:IM-11696-356	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	ensembl:ENSG00000070423(gene)|ensembl:ENST00000292363(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR039525|interpro:IPR039571|interpro:IPR039572|rcsb pdb:2N9O|rcsb pdb:2N9P|reactome:R-HSA-983168|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|refseq:NP_919442.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2019/01/23	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:4Z4AJGHJgoIUp9zhtfWcFBF1Fxw9606	intact-crc:9B0AD70EE37187BE|rigid:S4TqswCARBkBxllNufpvfgJymss	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q9HCM9	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-739510|uniprotkb:Q5STG4|uniprotkb:Q76BL3|uniprotkb:Q8IYT9|uniprotkb:Q96IB6|ensembl:ENSP00000365844|ensembl:ENSP00000373096|ensembl:ENSP00000379796|ensembl:ENSP00000391917|ensembl:ENSP00000397043|ensembl:ENSP00000398355|ensembl:ENSP00000409902|ensembl:ENSP00000411949|ensembl:ENSP00000447835|ensembl:ENSP00000448462|ensembl:ENSP00000448572|ensembl:ENSP00000449272|ensembl:ENSP00000449847|ensembl:ENSP00000450288|uniprotkb:Q5STG3	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:tri39_human(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340453|imex:IM-11696-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376656(transcript)|ensembl:ENST00000383602(transcript)|ensembl:ENST00000396547(transcript)|ensembl:ENST00000413715(transcript)|ensembl:ENST00000424575(transcript)|ensembl:ENST00000445206(transcript)|ensembl:ENST00000426469(transcript)|ensembl:ENST00000451715(transcript)|ensembl:ENST00000547030(transcript)|ensembl:ENST00000548002(transcript)|ensembl:ENST00000549841(transcript)|ensembl:ENST00000550282(transcript)|ensembl:ENST00000552337(transcript)|ensembl:ENST00000552520(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035033|interpro:IPR043136|mint:Q9HCM9|rcsb pdb:2DID|rcsb pdb:2DIF|rcsb pdb:2ECJ|reactome:R-HSA-983168|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_067076.2|refseq:NP_742013.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:xMCXGcMTqCjzLQzC53o81S4gqZA9606	intact-crc:2A3E23450D0DC7B2|rigid:Emegc12shc66EwkEHiPg5odZywA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BH1	uniprotkb:P62837	intact:EBI-2129220|uniprotkb:A8K0D6|uniprotkb:Q9H874|uniprotkb:Q53HQ5|ensembl:ENSP00000295704	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:rnf25_human(display_long)|uniprotkb:RNF25(gene name)|psi-mi:RNF25(display_short)|uniprotkb:RING finger protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF25(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340456|imex:IM-11696-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071898.2|dip:DIP-29063N|ensembl:ENSG00000163481(gene)|ensembl:ENST00000295704(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR039133|rcsb pdb:2DAY|rcsb pdb:2DMF|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|reactome:R-HSA-983168	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:YyCN7mH4eng9G05zRci49oJzKO09606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:02555A95C6D57235|rigid:rCT9zFgXHAZtDBAwGjlnU2qDz0I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q96GF1	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-2340249|uniprotkb:A8K5C1|uniprotkb:A9X3T8|uniprotkb:Q8N900|ensembl:ENSP00000320508|ensembl:ENSP00000427755	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:rn185_human(display_long)|uniprotkb:RNF185(gene name)|psi-mi:RNF185(display_short)|uniprotkb:RING finger protein 185(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF185(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340465|imex:IM-11696-28	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_001129297.1|refseq:NP_689480.2|ensembl:ENSG00000138942(gene)|ensembl:ENST00000326132(transcript)|ensembl:ENST00000518626(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:ivzbt31KPTKL/Rc1Wzs3h80XJac9606	intact-crc:11E09C63031125CA|rigid:TY8PUz5B4uz7aTCESpnfF60gVGI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZR9	uniprotkb:P62837	intact:EBI-2340370|uniprotkb:Q9C028|uniprotkb:A6NI31|intact:EBI-2796718|ensembl:ENSP00000496301	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:trim8_human(display_long)|uniprotkb:Tripartite motif-containing protein 8(gene name synonym)|uniprotkb:TRIM8(gene name)|psi-mi:TRIM8(display_short)|uniprotkb:GERP(gene name synonym)|uniprotkb:RNF27(gene name synonym)|uniprotkb:RING finger protein 27(gene name synonym)|uniprotkb:Glioblastoma-expressed RING finger protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM8(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340459|imex:IM-11696-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112174.2|ensembl:ENSG00000171206(gene)|ensembl:ENST00000643721(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0016740"(transferase activity)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902187"|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-877300	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:WFqavXVFV3/XbJSA2k06Pg9Eaag9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:B92D942F845F78F3|rigid:oCFarhXvuqAZ3OfMmxwDBAubQd4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8ND25	uniprotkb:P62837	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340462|imex:IM-11696-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:7E8494303CF86BBD|rigid:s+LFkHsZf1nUxmTPCbLhyDRZrW4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TDB6	uniprotkb:P62837	intact:EBI-2340392|uniprotkb:Q5MJP7|uniprotkb:Q53ZZ3|uniprotkb:B3KWH6|ensembl:ENSP00000296161	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:dtx3l_human(display_long)|uniprotkb:DTX3L(gene name)|psi-mi:DTX3L(display_short)|uniprotkb:BBAP(gene name synonym)|uniprotkb:B-lymphoma- and BAL-associated protein(gene name synonym)|uniprotkb:Rhysin-2(gene name synonym)|uniprotkb:Protein deltex-3-like(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3L(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340474|imex:IM-11696-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612144.1|ensembl:ENSG00000163840(gene)|ensembl:ENST00000296161(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0015031"(protein transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:2000646"(positive regulation of receptor catabolic process)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|interpro:IPR042843|rcsb pdb:3PG6|reactome:R-HSA-983168	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:d2ctDfd7pj1wRA3HxmyWJ5nL19Y9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:320F18C3A61FB0DC|rigid:eKXnOBqAdj/Po9RRBcD3RYwQ+Hc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q96A37	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-2130320|uniprotkb:B3KQ03|uniprotkb:Q96DM0|uniprotkb:D3DX75|uniprotkb:H3BTU8|ensembl:ENSP00000326095	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:rn166_human(display_long)|uniprotkb:RNF166(gene name)|psi-mi:RNF166(display_short)|uniprotkb:RING finger protein 166(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF166(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340468|imex:IM-11696-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_001165286.1|refseq:NP_001165287.1|refseq:NP_849163.1|refseq:XP_016878402.1|ensembl:ENSG00000158717(gene)|ensembl:ENST00000312838(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:QV195sbjVofHePvnO8nsleiWSkg9606	intact-crc:BCFFD797BD6038DB|rigid:GOIeZ2gjCxMH1Pp5jngDfEVmza4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BQ3	uniprotkb:P62837	intact:EBI-2129899|uniprotkb:Q53TJ7|ensembl:ENSP00000272395	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:tri43_human(display_long)|uniprotkb:TRIM43(gene name)|psi-mi:TRIM43(display_short)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340471|imex:IM-11696-30	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_620155.1|ensembl:ENSG00000144015(gene)|ensembl:ENST00000272395(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0045087"(innate immune response)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR043136	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pfo60amX0NFspl9zqQ/Cgek6yO09606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:3ED5929946F9BA85|rigid:W93yDf8FSdn99DT1VR3Q0MJo0x8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q8N9I9	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-2340258|uniprotkb:Q8NDS8|uniprotkb:Q8NAU6|uniprotkb:Q53ZZ2|ensembl:ENSP00000338050|ensembl:ENSP00000447873|ensembl:ENSP00000449294	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:dtx3_human(display_long)|uniprotkb:DTX3(gene name)|psi-mi:DTX3(display_short)|uniprotkb:RNF154(gene name synonym)|uniprotkb:RING finger protein 154(gene name synonym)|uniprotkb:Protein deltex-3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340477|imex:IM-11696-32	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_001273174.1|refseq:NP_001273175.1|refseq:XP_011536324.1|refseq:NP_848597.1|refseq:XP_005268754.1|refseq:XP_005268755.1|refseq:XP_005268757.1|refseq:XP_005268760.1|ensembl:ENSG00000178498(gene)|ensembl:ENST00000337737(transcript)|ensembl:ENST00000548198(transcript)|ensembl:ENST00000548804(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:Ma7JBhgMdFofCeWESbf8h1iLAHY9606	intact-crc:F55CD6B416E25EA5|rigid:mld1AXscTP5NUHnc2K5JsEamOoE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P98170	uniprotkb:P61077	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340480|imex:IM-11696-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:322E5BA721054360|rigid:gL2RfBy1oyIDMiIgYmf+ehuqNrg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q99496	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340489|imex:IM-11696-36	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	intact-crc:5F48DF9A8D133BB9|rigid:JFqRJJp5pNPmc4EDvqw1spti9N0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:O15344	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-2340316|uniprotkb:Q9BZX5|uniprotkb:O75361|uniprotkb:B2RCG2|ensembl:ENSP00000312678|ensembl:ENSP00000370156|ensembl:ENSP00000370157|ensembl:ENSP00000370162|ensembl:ENSP00000370164|ensembl:ENSP00000414521	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:tri18_human(display_long)|uniprotkb:MID1(gene name)|psi-mi:MID1(display_short)|uniprotkb:FXY(gene name synonym)|uniprotkb:RNF59(gene name synonym)|uniprotkb:TRIM18(gene name synonym)|uniprotkb:XPRF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 18(gene name synonym)|uniprotkb:Putative transcription factor XPRF(gene name synonym)|uniprotkb:Midin(gene name synonym)|uniprotkb:RING finger protein 59(gene name synonym)|uniprotkb:RING finger protein Midline-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Midline-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340483|imex:IM-11696-34	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:NP_000372.1|refseq:NP_001092094.1|refseq:NP_001180206.1|refseq:NP_001180207.1|refseq:NP_001180208.1|refseq:NP_001180209.1|refseq:NP_001180210.1|refseq:NP_150632.1|refseq:NP_001334662.1|refseq:XP_016885025.1|refseq:XP_016885029.1|ensembl:ENSG00000101871(gene)|ensembl:ENST00000317552(transcript)|ensembl:ENST00000380779(transcript)|ensembl:ENST00000380780(transcript)|ensembl:ENST00000380785(transcript)|ensembl:ENST00000380787(transcript)|ensembl:ENST00000453318(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016740"(transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003649(B-box, C-terminal)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR027727|interpro:IPR036116|interpro:IPR040859|interpro:IPR043136|rcsb pdb:2DQ5|rcsb pdb:2FFW|rcsb pdb:2JUN|rcsb pdb:5IM8|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:NGlMGyFT7GEcrzVR/Iw4LitMBig9606	intact-crc:E406AFCFDD8D3ED8|rigid:MHSlbNYksdFk/Vd0RVeDBxnnnC4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:P14373	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340486|imex:IM-11696-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:78771D9E4D8DF87C|rigid:sLg39I0PNHuzSauV/9gKNV2UZdA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q9UBS8	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-2130308|uniprotkb:B7ZLV2|uniprotkb:A0AV26|uniprotkb:A6NMR2|uniprotkb:B3KN72|uniprotkb:O94793|uniprotkb:Q6IBV0|uniprotkb:A8MTW5|uniprotkb:D3DQE4|ensembl:ENSP00000324956|ensembl:ENSP00000348462|ensembl:ENSP00000378027|ensembl:ENSP00000378028	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:rnf14_human(display_long)|uniprotkb:RNF14(gene name)|psi-mi:RNF14(display_short)|uniprotkb:ARA54(gene name synonym)|uniprotkb:RING finger protein 14(gene name synonym)|uniprotkb:Androgen receptor-associated protein 54(gene name synonym)|uniprotkb:Triad2 protein(gene name synonym)|uniprotkb:HFB30(gene name synonym)|uniprotkb:HRIHFB2038(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340498|imex:IM-11696-360	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:XP_011536016.1|refseq:NP_001188294.1|refseq:NP_004281.1|refseq:NP_899645.1|refseq:NP_899646.1|refseq:NP_899647.1|refseq:NP_899648.1|refseq:XP_016865559.1|refseq:XP_016865560.1|refseq:XP_016865561.1|refseq:XP_005268593.1|refseq:XP_005268594.1|refseq:XP_005268596.1|refseq:XP_005268597.1|refseq:XP_005268598.1|ensembl:ENSG00000013561(gene)|ensembl:ENST00000347642(transcript)|ensembl:ENST00000356143(transcript)|ensembl:ENST00000394519(transcript)|ensembl:ENST00000394520(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017907|interpro:IPR031127|interpro:IPR031128|interpro:IPR044066|mint:Q9UBS8|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:zCNZ6kHw7XNUvpVBRQSgZ7ffJ9U9606	intact-crc:2DD36B7F6B582886|rigid:ON4jWVfcHWVC1GfYL8Xy2KdG49g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q99942	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340492|imex:IM-11696-358	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606	intact-crc:E8828695B6886CBD|rigid:zjux9cYhq7vgGCXRmLAwP8dkakU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13064	uniprotkb:P61077	intact:EBI-2340269|ensembl:ENSP00000313881	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340495|imex:IM-11696-359	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:456C4C0AC65FCFF4|rigid:DIfI4U4FLKmj9n0VjZNPcJUtlDg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q86Y13	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340501|imex:IM-11696-361	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:86F34F61381B9EED|rigid:5IGduJK+RPAaEneAVKN0j+XN1XA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5U6	uniprotkb:P61077	intact:EBI-714023|uniprotkb:Q92550|uniprotkb:Q9NPP8|uniprotkb:Q9ULW4|ensembl:ENSP00000322242	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:rnf10_human(display_long)|uniprotkb:RNF10(gene name)|psi-mi:RNF10(display_short)|uniprotkb:KIAA0262(gene name synonym)|uniprotkb:RIE2(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340504|imex:IM-11696-362	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055683.3|refseq:NP_001317403.1|ensembl:ENSG00000022840(gene)|ensembl:ENST00000325954(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039739|mint:Q8N5U6	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Bca0Ae456x1eCsdlduoCbn7coUQ9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:275129EF5150B81A|rigid:HHKhdEW3g0TNKmv04WyL2CYsxzE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:O94941	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-751901|uniprotkb:Q6IAR5|uniprotkb:Q86X87|uniprotkb:Q9H4J2|ensembl:ENSP00000217173	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:rnf37_human(display_long)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 5(gene name synonym)|uniprotkb:U-box domain-containing protein 5(gene name synonym)|uniprotkb:UBOX5(gene name)|psi-mi:UBOX5(display_short)|uniprotkb:KIAA0860(gene name synonym)|uniprotkb:RNF37(gene name synonym)|uniprotkb:UBCE7IP5(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF37(gene name synonym)|uniprotkb:UIP5(gene name synonym)|uniprotkb:UbcM4-interacting protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340507|imex:IM-11696-363	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:NP_055763.1|refseq:NP_955447.1|ensembl:ENSG00000185019(gene)|ensembl:ENST00000217173(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039847|interpro:IPR039925|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:bHUiSJ345KLIwL+xD2qH/CJVqL09606	intact-crc:2AE6D8B025C4DA7E|rigid:3k9hgaUPCFmXENBywXz4aTnwHD0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y3C5	uniprotkb:P61077	intact:EBI-396669|intact:EBI-2129167|uniprotkb:A8KAI2|uniprotkb:Q5T7R8|ensembl:ENSP00000242719	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:rnf11_human(display_long)|uniprotkb:CGI-123(orf name)|uniprotkb:RNF11(gene name)|psi-mi:RNF11(display_short)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340510|imex:IM-11696-364	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055187.1|ensembl:ENSP00000242719|ensembl:ENSG00000123091(gene)|ensembl:ENST00000242719(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042981|mint:Q9Y3C5	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Uj0YAf/t+AdYbMd6fgQ8hVKoP0w9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:ECB82F55816BBDE6|rigid:AlTDSwn1f4OdjIMaEZu3NBsTL/4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BV68	uniprotkb:P61077	intact:EBI-357322|ensembl:ENSP00000292363|uniprotkb:Q9NWX1|intact:EBI-11064977	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:rn126_human(display_long)|uniprotkb:RNF126(gene name)|psi-mi:RNF126(display_short)|uniprotkb:RING finger protein 126(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340519|imex:IM-11696-367	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000070423(gene)|ensembl:ENST00000292363(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR039525|interpro:IPR039571|interpro:IPR039572|rcsb pdb:2N9O|rcsb pdb:2N9P|reactome:R-HSA-983168|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|refseq:NP_919442.1	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2019/01/23	rogid:4Z4AJGHJgoIUp9zhtfWcFBF1Fxw9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:04C36ABB22545CD2|rigid:fmJugtM4WBOn96fZJwoySPRs41k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q6ZNA4	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-2129175|uniprotkb:Q6ZMU2|uniprotkb:Q7L428|uniprotkb:Q7Z346|uniprotkb:Q8N1P9|uniprotkb:Q8WUA3|uniprotkb:Q9NSR1|uniprotkb:Q6P9A4|uniprotkb:C9JUS4|uniprotkb:H0YN55|ensembl:ENSP00000452732|intact:EBI-28970158	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:rn111_human(display_long)|uniprotkb:RNF111(gene name)|psi-mi:RNF111(display_short)|uniprotkb:RING finger protein 111(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Arkadia(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340513|imex:IM-11696-365	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:NP_060080.6|ensembl:ENST00000348370|ensembl:ENSP00000288199|ensembl:ENSP00000452732|ensembl:ENST00000559209|ensembl:ENSP00000453872|ensembl:ENST00000561186|ensembl:ENSP00000453015|refseq:NP_001317260.1|refseq:XP_016877827.1|refseq:XP_006720642.1|refseq:NP_001257459.1|refseq:NP_001257457.1|refseq:NP_001257458.1|ensembl:ENSG00000157450(gene)|ensembl:ENST00000557998(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR029306|rcsb pdb:2KIZ|rcsb pdb:5LG0|rcsb pdb:5LG7|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-5696395|reactome:R-HSA-983168|go:"GO:0032184"(SUMO polymer binding)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:6SY5oMr5u4mnVi+zdRboVljMGa09606	intact-crc:FD89A52A8ABEB145|rigid:PsNIrksvD3b62VgSXX2MZBK5B/w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q6PCD5	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-2129159|uniprotkb:Q9H9Q3|uniprotkb:Q9NVT4|uniprotkb:Q5XKR3|uniprotkb:A8K585|uniprotkb:B2RE35|uniprotkb:D3DUJ8|ensembl:ENSP00000354361|ensembl:ENSP00000460049	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:rfwd3_human(display_long)|uniprotkb:RFWD3(gene name)|psi-mi:RFWD3(display_short)|uniprotkb:RING finger and WD repeat domain-containing protein 3(gene name synonym)|uniprotkb:RNF201(gene name synonym)|uniprotkb:RING finger protein 201(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340516|imex:IM-11696-366	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:XP_011521493.1|refseq:NP_060594.3|refseq:XP_016878880.1|refseq:XP_005256078.1|refseq:XP_005256079.1|dip:DIP-52688N|ensembl:ENSG00000168411(gene)|ensembl:ENST00000361070(transcript)|ensembl:ENST00000571750(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031297"(replication fork processing)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037381|rcsb pdb:6CVZ	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:r7gkMbkS0GKPVn9riLPR34KFaKk9606	intact-crc:431F9618461C2B60|rigid:+F/e6WjX+ZsxHZv5e3S/OX+9aYw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y508	uniprotkb:P61077	intact:EBI-723587|uniprotkb:Q6N0B0|uniprotkb:B2RDQ9|uniprotkb:B4DWY5|uniprotkb:E1P627|ensembl:ENSP00000244061	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:rn114_human(display_long)|uniprotkb:Zinc finger protein 313(gene name synonym)|uniprotkb:RNF114(gene name)|psi-mi:RNF114(display_short)|uniprotkb:ZNF313(gene name synonym)|uniprotkb:ZNF228(gene name synonym)|uniprotkb:Zinc finger protein 228(gene name synonym)|uniprotkb:RING finger protein 114(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF114(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340522|imex:IM-11696-368	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061153.1|ensembl:ENSG00000124226(gene)|ensembl:ENST00000244061(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR034734|interpro:IPR042716|reactome:R-HSA-983168	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:R1fX8xaGuIhy/M6cLzPeyfJBf649606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:98D3A6B848C96375|rigid:+wgGpl3dNNFOXg/ZCDLA8tdYyxw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCM9	uniprotkb:P61077	intact:EBI-739510|uniprotkb:Q5STG4|uniprotkb:Q76BL3|uniprotkb:Q8IYT9|uniprotkb:Q96IB6|ensembl:ENSP00000365844|ensembl:ENSP00000373096|ensembl:ENSP00000379796|ensembl:ENSP00000391917|ensembl:ENSP00000397043|ensembl:ENSP00000398355|ensembl:ENSP00000409902|ensembl:ENSP00000411949|ensembl:ENSP00000447835|ensembl:ENSP00000448462|ensembl:ENSP00000448572|ensembl:ENSP00000449272|ensembl:ENSP00000449847|ensembl:ENSP00000450288|uniprotkb:Q5STG3	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:tri39_human(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340525|imex:IM-11696-369	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376656(transcript)|ensembl:ENST00000383602(transcript)|ensembl:ENST00000396547(transcript)|ensembl:ENST00000413715(transcript)|ensembl:ENST00000424575(transcript)|ensembl:ENST00000445206(transcript)|ensembl:ENST00000426469(transcript)|ensembl:ENST00000451715(transcript)|ensembl:ENST00000547030(transcript)|ensembl:ENST00000548002(transcript)|ensembl:ENST00000549841(transcript)|ensembl:ENST00000550282(transcript)|ensembl:ENST00000552337(transcript)|ensembl:ENST00000552520(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035033|interpro:IPR043136|mint:Q9HCM9|rcsb pdb:2DID|rcsb pdb:2DIF|rcsb pdb:2ECJ|reactome:R-HSA-983168|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_067076.2|refseq:NP_742013.1	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xMCXGcMTqCjzLQzC53o81S4gqZA9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:B5F79EF0CC281CDE|rigid:cY5DYTzyiyOtOd8hnQECg1Onep8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8ND25	uniprotkb:P61077	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340534|imex:IM-11696-372	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:E14D2985FDDDB0D1|rigid:PKp+UXAyI8kz+DVxHlEfZ9JDoEU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q96BH1	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-2129220|uniprotkb:A8K0D6|uniprotkb:Q9H874|uniprotkb:Q53HQ5|ensembl:ENSP00000295704	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:rnf25_human(display_long)|uniprotkb:RNF25(gene name)|psi-mi:RNF25(display_short)|uniprotkb:RING finger protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF25(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340528|imex:IM-11696-370	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:NP_071898.2|dip:DIP-29063N|ensembl:ENSG00000163481(gene)|ensembl:ENST00000295704(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR039133|rcsb pdb:2DAY|rcsb pdb:2DMF|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:YyCN7mH4eng9G05zRci49oJzKO09606	intact-crc:9D9CE72007F0A959|rigid:8lTGkXyjoGK73qPlh3cIjtFLnB8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZR9	uniprotkb:P61077	intact:EBI-2340370|uniprotkb:Q9C028|uniprotkb:A6NI31|intact:EBI-2796718|ensembl:ENSP00000496301	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:trim8_human(display_long)|uniprotkb:Tripartite motif-containing protein 8(gene name synonym)|uniprotkb:TRIM8(gene name)|psi-mi:TRIM8(display_short)|uniprotkb:GERP(gene name synonym)|uniprotkb:RNF27(gene name synonym)|uniprotkb:RING finger protein 27(gene name synonym)|uniprotkb:Glioblastoma-expressed RING finger protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM8(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340531|imex:IM-11696-371	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112174.2|ensembl:ENSG00000171206(gene)|ensembl:ENST00000643721(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0016740"(transferase activity)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902187"|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-877300	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:WFqavXVFV3/XbJSA2k06Pg9Eaag9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:26E4299A457AA39F|rigid:YsvzyjZxfXmPMXMhvW5VR/8RbqQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BQ3	uniprotkb:P61077	intact:EBI-2129899|uniprotkb:Q53TJ7|ensembl:ENSP00000272395	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:tri43_human(display_long)|uniprotkb:TRIM43(gene name)|psi-mi:TRIM43(display_short)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340543|imex:IM-11696-375	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_620155.1|ensembl:ENSG00000144015(gene)|ensembl:ENST00000272395(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0045087"(innate immune response)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR043136	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pfo60amX0NFspl9zqQ/Cgek6yO09606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:A11C2F2C87DC61E9|rigid:j4LD2FXtTTTjJ8XFrFcNZg8EK+0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96GF1	uniprotkb:P61077	intact:EBI-2340249|uniprotkb:A8K5C1|uniprotkb:A9X3T8|uniprotkb:Q8N900|ensembl:ENSP00000320508|ensembl:ENSP00000427755	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:rn185_human(display_long)|uniprotkb:RNF185(gene name)|psi-mi:RNF185(display_short)|uniprotkb:RING finger protein 185(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF185(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340537|imex:IM-11696-373	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001129297.1|refseq:NP_689480.2|ensembl:ENSG00000138942(gene)|ensembl:ENST00000326132(transcript)|ensembl:ENST00000518626(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ivzbt31KPTKL/Rc1Wzs3h80XJac9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:8E2921D6C234FEA6|rigid:fv+PiK0BbV1cQFGKWEC1arz/6fI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q96A37	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-2130320|uniprotkb:B3KQ03|uniprotkb:Q96DM0|uniprotkb:D3DX75|uniprotkb:H3BTU8|ensembl:ENSP00000326095	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:rn166_human(display_long)|uniprotkb:RNF166(gene name)|psi-mi:RNF166(display_short)|uniprotkb:RING finger protein 166(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF166(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340540|imex:IM-11696-374	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:NP_001165286.1|refseq:NP_001165287.1|refseq:NP_849163.1|refseq:XP_016878402.1|ensembl:ENSG00000158717(gene)|ensembl:ENST00000312838(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:QV195sbjVofHePvnO8nsleiWSkg9606	intact-crc:23366A227C45E3B7|rigid:xVXyiHb29IibRLskR464k85DUJI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q8TDB6	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-2340392|uniprotkb:Q5MJP7|uniprotkb:Q53ZZ3|uniprotkb:B3KWH6|ensembl:ENSP00000296161	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:dtx3l_human(display_long)|uniprotkb:DTX3L(gene name)|psi-mi:DTX3L(display_short)|uniprotkb:BBAP(gene name synonym)|uniprotkb:B-lymphoma- and BAL-associated protein(gene name synonym)|uniprotkb:Rhysin-2(gene name synonym)|uniprotkb:Protein deltex-3-like(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3L(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340546|imex:IM-11696-376	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:NP_612144.1|ensembl:ENSG00000163840(gene)|ensembl:ENST00000296161(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0015031"(protein transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:2000646"(positive regulation of receptor catabolic process)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|interpro:IPR042843|rcsb pdb:3PG6|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:d2ctDfd7pj1wRA3HxmyWJ5nL19Y9606	intact-crc:ADC6A576673A6BB0|rigid:Gob/PwFFm0MnTpPb9W5eXPk0Kjs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N9I9	uniprotkb:P61077	intact:EBI-2340258|uniprotkb:Q8NDS8|uniprotkb:Q8NAU6|uniprotkb:Q53ZZ2|ensembl:ENSP00000338050|ensembl:ENSP00000447873|ensembl:ENSP00000449294	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:dtx3_human(display_long)|uniprotkb:DTX3(gene name)|psi-mi:DTX3(display_short)|uniprotkb:RNF154(gene name synonym)|uniprotkb:RING finger protein 154(gene name synonym)|uniprotkb:Protein deltex-3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340549|imex:IM-11696-377	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273174.1|refseq:NP_001273175.1|refseq:XP_011536324.1|refseq:NP_848597.1|refseq:XP_005268754.1|refseq:XP_005268755.1|refseq:XP_005268757.1|refseq:XP_005268760.1|ensembl:ENSG00000178498(gene)|ensembl:ENST00000337737(transcript)|ensembl:ENST00000548198(transcript)|ensembl:ENST00000548804(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Ma7JBhgMdFofCeWESbf8h1iLAHY9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:6A956B01D7C785C9|rigid:QRorvNANSGfD8pJNIfgEzwCVTXc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q9UBS8	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-2130308|uniprotkb:B7ZLV2|uniprotkb:A0AV26|uniprotkb:A6NMR2|uniprotkb:B3KN72|uniprotkb:O94793|uniprotkb:Q6IBV0|uniprotkb:A8MTW5|uniprotkb:D3DQE4|ensembl:ENSP00000324956|ensembl:ENSP00000348462|ensembl:ENSP00000378027|ensembl:ENSP00000378028	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:rnf14_human(display_long)|uniprotkb:RNF14(gene name)|psi-mi:RNF14(display_short)|uniprotkb:ARA54(gene name synonym)|uniprotkb:RING finger protein 14(gene name synonym)|uniprotkb:Androgen receptor-associated protein 54(gene name synonym)|uniprotkb:Triad2 protein(gene name synonym)|uniprotkb:HFB30(gene name synonym)|uniprotkb:HRIHFB2038(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340558|imex:IM-11696-380	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:XP_011536016.1|refseq:NP_001188294.1|refseq:NP_004281.1|refseq:NP_899645.1|refseq:NP_899646.1|refseq:NP_899647.1|refseq:NP_899648.1|refseq:XP_016865559.1|refseq:XP_016865560.1|refseq:XP_016865561.1|refseq:XP_005268593.1|refseq:XP_005268594.1|refseq:XP_005268596.1|refseq:XP_005268597.1|refseq:XP_005268598.1|ensembl:ENSG00000013561(gene)|ensembl:ENST00000347642(transcript)|ensembl:ENST00000356143(transcript)|ensembl:ENST00000394519(transcript)|ensembl:ENST00000394520(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017907|interpro:IPR031127|interpro:IPR031128|interpro:IPR044066|mint:Q9UBS8|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:zCNZ6kHw7XNUvpVBRQSgZ7ffJ9U9606	intact-crc:91E36A68B6CA604B|rigid:cWoo5UVN1w9SmglUAeEU1p9omB4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q99496	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340552|imex:IM-11696-378	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	intact-crc:E378DE8D50817374|rigid:jovaPKuqfrJCajnWExvRSzzj08I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q99942	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340555|imex:IM-11696-379	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606	intact-crc:54B287826B1A2470|rigid:AcdWiqv6Y/7nYrzVcYkvHRO7NcM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q8N5U6	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-714023|uniprotkb:Q92550|uniprotkb:Q9NPP8|uniprotkb:Q9ULW4|ensembl:ENSP00000322242	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:rnf10_human(display_long)|uniprotkb:RNF10(gene name)|psi-mi:RNF10(display_short)|uniprotkb:KIAA0262(gene name synonym)|uniprotkb:RIE2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340561|imex:IM-11696-381	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_055683.3|refseq:NP_001317403.1|ensembl:ENSG00000022840(gene)|ensembl:ENST00000325954(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039739|mint:Q8N5U6	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:Bca0Ae456x1eCsdlduoCbn7coUQ9606	intact-crc:9B6128F88CC2F0D7|rigid:kV9YdBEIaYYjIVJHjzVaKsCxfnU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q9HCM9	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-739510|uniprotkb:Q5STG4|uniprotkb:Q76BL3|uniprotkb:Q8IYT9|uniprotkb:Q96IB6|ensembl:ENSP00000365844|ensembl:ENSP00000373096|ensembl:ENSP00000379796|ensembl:ENSP00000391917|ensembl:ENSP00000397043|ensembl:ENSP00000398355|ensembl:ENSP00000409902|ensembl:ENSP00000411949|ensembl:ENSP00000447835|ensembl:ENSP00000448462|ensembl:ENSP00000448572|ensembl:ENSP00000449272|ensembl:ENSP00000449847|ensembl:ENSP00000450288|uniprotkb:Q5STG3	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:tri39_human(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340564|imex:IM-11696-382	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376656(transcript)|ensembl:ENST00000383602(transcript)|ensembl:ENST00000396547(transcript)|ensembl:ENST00000413715(transcript)|ensembl:ENST00000424575(transcript)|ensembl:ENST00000445206(transcript)|ensembl:ENST00000426469(transcript)|ensembl:ENST00000451715(transcript)|ensembl:ENST00000547030(transcript)|ensembl:ENST00000548002(transcript)|ensembl:ENST00000549841(transcript)|ensembl:ENST00000550282(transcript)|ensembl:ENST00000552337(transcript)|ensembl:ENST00000552520(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035033|interpro:IPR043136|mint:Q9HCM9|rcsb pdb:2DID|rcsb pdb:2DIF|rcsb pdb:2ECJ|reactome:R-HSA-983168|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_067076.2|refseq:NP_742013.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:xMCXGcMTqCjzLQzC53o81S4gqZA9606	intact-crc:09C79FE711BA5413|rigid:WWiWa6QEdd4f9jZUHTNe9K0fmYw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96A37	uniprotkb:P51965	intact:EBI-2130320|uniprotkb:B3KQ03|uniprotkb:Q96DM0|uniprotkb:D3DX75|uniprotkb:H3BTU8|ensembl:ENSP00000326095	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:rn166_human(display_long)|uniprotkb:RNF166(gene name)|psi-mi:RNF166(display_short)|uniprotkb:RING finger protein 166(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF166(gene name synonym)	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340573|imex:IM-11696-385	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001165286.1|refseq:NP_001165287.1|refseq:NP_849163.1|refseq:XP_016878402.1|ensembl:ENSG00000158717(gene)|ensembl:ENST00000312838(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:QV195sbjVofHePvnO8nsleiWSkg9606	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	intact-crc:9F066B35A1D7AB7A|rigid:OYRACbigHx/8MU0DXsll/X/yAgA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q96BH1	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-2129220|uniprotkb:A8K0D6|uniprotkb:Q9H874|uniprotkb:Q53HQ5|ensembl:ENSP00000295704	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:rnf25_human(display_long)|uniprotkb:RNF25(gene name)|psi-mi:RNF25(display_short)|uniprotkb:RING finger protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF25(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340567|imex:IM-11696-383	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_071898.2|dip:DIP-29063N|ensembl:ENSG00000163481(gene)|ensembl:ENST00000295704(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR039133|rcsb pdb:2DAY|rcsb pdb:2DMF|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:YyCN7mH4eng9G05zRci49oJzKO09606	intact-crc:21ACE637DA62E194|rigid:7mBQvUq2KgkzPOEmlSowFwKSthg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q8ND25	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340570|imex:IM-11696-384	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	intact-crc:5D7D2892204FF81C|rigid:74CD2YeFhCluQGTEJedBmRKBOPw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LR5	uniprotkb:Q99496	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340582|imex:IM-11696-388	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	intact-crc:9309998E05832310|rigid:eBw2Q+ddskC0WYDEKBxy5IQO5cE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q8TDB6	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-2340392|uniprotkb:Q5MJP7|uniprotkb:Q53ZZ3|uniprotkb:B3KWH6|ensembl:ENSP00000296161	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:dtx3l_human(display_long)|uniprotkb:DTX3L(gene name)|psi-mi:DTX3L(display_short)|uniprotkb:BBAP(gene name synonym)|uniprotkb:B-lymphoma- and BAL-associated protein(gene name synonym)|uniprotkb:Rhysin-2(gene name synonym)|uniprotkb:Protein deltex-3-like(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3L(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340576|imex:IM-11696-386	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_612144.1|ensembl:ENSG00000163840(gene)|ensembl:ENST00000296161(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0015031"(protein transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:2000646"(positive regulation of receptor catabolic process)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|interpro:IPR042843|rcsb pdb:3PG6|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:d2ctDfd7pj1wRA3HxmyWJ5nL19Y9606	intact-crc:11F6A461BAA8237D|rigid:h40IFGIkzqPTSLmurHgfcvS3750	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LR5	uniprotkb:P36406	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340579|imex:IM-11696-387	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	intact-crc:2D196AE2B6DFD90E|rigid:Zu+5qk+elK46Pt5odm0jIaoc/G8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99942	uniprotkb:Q96LR5	intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340585|imex:IM-11696-389	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:24C3C0813E187414|rigid:nu8BcTVJKrnEEvtTo3E1ZK0fbsA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LR5	uniprotkb:Q9UBS8	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-2130308|uniprotkb:B7ZLV2|uniprotkb:A0AV26|uniprotkb:A6NMR2|uniprotkb:B3KN72|uniprotkb:O94793|uniprotkb:Q6IBV0|uniprotkb:A8MTW5|uniprotkb:D3DQE4|ensembl:ENSP00000324956|ensembl:ENSP00000348462|ensembl:ENSP00000378027|ensembl:ENSP00000378028	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:rnf14_human(display_long)|uniprotkb:RNF14(gene name)|psi-mi:RNF14(display_short)|uniprotkb:ARA54(gene name synonym)|uniprotkb:RING finger protein 14(gene name synonym)|uniprotkb:Androgen receptor-associated protein 54(gene name synonym)|uniprotkb:Triad2 protein(gene name synonym)|uniprotkb:HFB30(gene name synonym)|uniprotkb:HRIHFB2038(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340588|imex:IM-11696-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	refseq:XP_011536016.1|refseq:NP_001188294.1|refseq:NP_004281.1|refseq:NP_899645.1|refseq:NP_899646.1|refseq:NP_899647.1|refseq:NP_899648.1|refseq:XP_016865559.1|refseq:XP_016865560.1|refseq:XP_016865561.1|refseq:XP_005268593.1|refseq:XP_005268594.1|refseq:XP_005268596.1|refseq:XP_005268597.1|refseq:XP_005268598.1|ensembl:ENSG00000013561(gene)|ensembl:ENST00000347642(transcript)|ensembl:ENST00000356143(transcript)|ensembl:ENST00000394519(transcript)|ensembl:ENST00000394520(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017907|interpro:IPR031127|interpro:IPR031128|interpro:IPR044066|mint:Q9UBS8|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:zCNZ6kHw7XNUvpVBRQSgZ7ffJ9U9606	intact-crc:E1922D6BE3C8302F|rigid:wbVLaJ3YqPaWRQbgkQn1IlRDpyA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y3C5	uniprotkb:Q96LR5	intact:EBI-396669|intact:EBI-2129167|uniprotkb:A8KAI2|uniprotkb:Q5T7R8|ensembl:ENSP00000242719	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:rnf11_human(display_long)|uniprotkb:CGI-123(orf name)|uniprotkb:RNF11(gene name)|psi-mi:RNF11(display_short)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340597|imex:IM-11696-40	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055187.1|ensembl:ENSP00000242719|ensembl:ENSG00000123091(gene)|ensembl:ENST00000242719(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042981|mint:Q9Y3C5	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Uj0YAf/t+AdYbMd6fgQ8hVKoP0w9606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:20F9694109FBA54F|rigid:bIUwMqnQa8jdkJchfraoST6gDvU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LR5	uniprotkb:Q86Y13	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340591|imex:IM-11696-38	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:D86752FB16690402|rigid:ftgZH8Rk9YSHDS85kTAFNLU0SAg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95376	uniprotkb:Q96LR5	intact:EBI-711158|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9|ensembl:ENSP00000348769|ensembl:ENSP00000403222	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340594|imex:IM-11696-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|ensembl:ENSG00000177479(gene)|ensembl:ENST00000356401(transcript)|ensembl:ENST00000449376(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|refseq:XP_016861020.1|refseq:XP_016861021.1	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:D909F097248BC2C0|rigid:cNlBcU0IMdyVp/s1PikoDuXGZVs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y508	uniprotkb:Q96LR5	intact:EBI-723587|uniprotkb:Q6N0B0|uniprotkb:B2RDQ9|uniprotkb:B4DWY5|uniprotkb:E1P627|ensembl:ENSP00000244061	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:rn114_human(display_long)|uniprotkb:Zinc finger protein 313(gene name synonym)|uniprotkb:RNF114(gene name)|psi-mi:RNF114(display_short)|uniprotkb:ZNF313(gene name synonym)|uniprotkb:ZNF228(gene name synonym)|uniprotkb:Zinc finger protein 228(gene name synonym)|uniprotkb:RING finger protein 114(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF114(gene name synonym)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340600|imex:IM-11696-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061153.1|ensembl:ENSG00000124226(gene)|ensembl:ENST00000244061(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR034734|interpro:IPR042716|reactome:R-HSA-983168	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:R1fX8xaGuIhy/M6cLzPeyfJBf649606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:5492E0ACC0597BDC|rigid:XTAXU8cHgE31js9r6To+Tz8smio	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LR5	uniprotkb:Q9HCM9	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-739510|uniprotkb:Q5STG4|uniprotkb:Q76BL3|uniprotkb:Q8IYT9|uniprotkb:Q96IB6|ensembl:ENSP00000365844|ensembl:ENSP00000373096|ensembl:ENSP00000379796|ensembl:ENSP00000391917|ensembl:ENSP00000397043|ensembl:ENSP00000398355|ensembl:ENSP00000409902|ensembl:ENSP00000411949|ensembl:ENSP00000447835|ensembl:ENSP00000448462|ensembl:ENSP00000448572|ensembl:ENSP00000449272|ensembl:ENSP00000449847|ensembl:ENSP00000450288|uniprotkb:Q5STG3	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:tri39_human(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340603|imex:IM-11696-42	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376656(transcript)|ensembl:ENST00000383602(transcript)|ensembl:ENST00000396547(transcript)|ensembl:ENST00000413715(transcript)|ensembl:ENST00000424575(transcript)|ensembl:ENST00000445206(transcript)|ensembl:ENST00000426469(transcript)|ensembl:ENST00000451715(transcript)|ensembl:ENST00000547030(transcript)|ensembl:ENST00000548002(transcript)|ensembl:ENST00000549841(transcript)|ensembl:ENST00000550282(transcript)|ensembl:ENST00000552337(transcript)|ensembl:ENST00000552520(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035033|interpro:IPR043136|mint:Q9HCM9|rcsb pdb:2DID|rcsb pdb:2DIF|rcsb pdb:2ECJ|reactome:R-HSA-983168|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_067076.2|refseq:NP_742013.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:xMCXGcMTqCjzLQzC53o81S4gqZA9606	intact-crc:79B6D8E444B80477|rigid:6QbgMraR7s5F/RLuXDtB4MJwlkg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LR5	uniprotkb:Q96GF1	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-2340249|uniprotkb:A8K5C1|uniprotkb:A9X3T8|uniprotkb:Q8N900|ensembl:ENSP00000320508|ensembl:ENSP00000427755	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:rn185_human(display_long)|uniprotkb:RNF185(gene name)|psi-mi:RNF185(display_short)|uniprotkb:RING finger protein 185(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF185(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340612|imex:IM-11696-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	refseq:NP_001129297.1|refseq:NP_689480.2|ensembl:ENSG00000138942(gene)|ensembl:ENST00000326132(transcript)|ensembl:ENST00000518626(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:ivzbt31KPTKL/Rc1Wzs3h80XJac9606	intact-crc:16F188506F7575B2|rigid:5ADYeJ35zwIHEGIvqn8FfM/L/Pg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BH1	uniprotkb:Q96LR5	intact:EBI-2129220|uniprotkb:A8K0D6|uniprotkb:Q9H874|uniprotkb:Q53HQ5|ensembl:ENSP00000295704	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:rnf25_human(display_long)|uniprotkb:RNF25(gene name)|psi-mi:RNF25(display_short)|uniprotkb:RING finger protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF25(gene name synonym)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340606|imex:IM-11696-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071898.2|dip:DIP-29063N|ensembl:ENSG00000163481(gene)|ensembl:ENST00000295704(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR039133|rcsb pdb:2DAY|rcsb pdb:2DMF|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|reactome:R-HSA-983168	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:YyCN7mH4eng9G05zRci49oJzKO09606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:BDF04F48B7C3AEDC|rigid:AD9qVaxUUvlXneheCNdxIN/pTg8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LR5	uniprotkb:Q8ND25	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340609|imex:IM-11696-44	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	intact-crc:FD1C17746E07DE8F|rigid:PyDQw1tJRP+kDtAbGY9NLrmF/fg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TDB6	uniprotkb:Q96LR5	intact:EBI-2340392|uniprotkb:Q5MJP7|uniprotkb:Q53ZZ3|uniprotkb:B3KWH6|ensembl:ENSP00000296161	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:dtx3l_human(display_long)|uniprotkb:DTX3L(gene name)|psi-mi:DTX3L(display_short)|uniprotkb:BBAP(gene name synonym)|uniprotkb:B-lymphoma- and BAL-associated protein(gene name synonym)|uniprotkb:Rhysin-2(gene name synonym)|uniprotkb:Protein deltex-3-like(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3L(gene name synonym)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340615|imex:IM-11696-46	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612144.1|ensembl:ENSG00000163840(gene)|ensembl:ENST00000296161(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0015031"(protein transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:2000646"(positive regulation of receptor catabolic process)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|interpro:IPR042843|rcsb pdb:3PG6|reactome:R-HSA-983168	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:d2ctDfd7pj1wRA3HxmyWJ5nL19Y9606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:7F51158EC4A6B3D8|rigid:FfVQDUJF+Vr5ZrSRSUgnVqj4dRo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P62256	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340633|imex:IM-11696-48	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	intact-crc:68EDFBA87BCB3435|rigid:taeQhXK1yH/WGqCCN3rzAV4SlDc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:Q86Y13	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340636|imex:IM-11696-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:7454CAF2FE889EBD|rigid:xIKixXTrmjZzBum5b8vL9aQpVkI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BYM8	uniprotkb:P62253	intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632	intact:EBI-2340619|uniprotkb:D3DTK0|uniprotkb:Q99462|uniprotkb:B2R7P2|ensembl:ENSP00000380178	psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym)	psi-mi:ub2g1_human(display_long)|uniprotkb:UBE2G1(gene name)|psi-mi:UBE2G1(display_short)|uniprotkb:UBE2G(gene name synonym)|uniprotkb:Ubiquitin-protein ligase G1(gene name synonym)|uniprotkb:Ubiquitin carrier protein G1(gene name synonym)|uniprotkb:E217K(gene name synonym)|uniprotkb:UBC7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme G1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340618|imex:IM-11696-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006453.1|refseq:NP_112506.2|ensembl:ENSG00000125826(gene)|ensembl:ENST00000356286(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR026261|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|dip:DIP-47737N	refseq:NP_003333.1|ensembl:ENSG00000132388(gene)|ensembl:ENST00000396981(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2AWF|rcsb pdb:6D68|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606	rogid:Yw3cuksmoC3miJRlMZhkBGFifso9606	intact-crc:61A8C39BD546FB89|rigid:30Km4xvyiHR4np8g2dOvjOjlxZU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O94941	uniprotkb:P62256	intact:EBI-751901|uniprotkb:Q6IAR5|uniprotkb:Q86X87|uniprotkb:Q9H4J2|ensembl:ENSP00000217173	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	psi-mi:rnf37_human(display_long)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 5(gene name synonym)|uniprotkb:U-box domain-containing protein 5(gene name synonym)|uniprotkb:UBOX5(gene name)|psi-mi:UBOX5(display_short)|uniprotkb:KIAA0860(gene name synonym)|uniprotkb:RNF37(gene name synonym)|uniprotkb:UBCE7IP5(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF37(gene name synonym)|uniprotkb:UIP5(gene name synonym)|uniprotkb:UbcM4-interacting protein 5(gene name synonym)	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340639|imex:IM-11696-50	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055763.1|refseq:NP_955447.1|ensembl:ENSG00000185019(gene)|ensembl:ENST00000217173(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039847|interpro:IPR039925|reactome:R-HSA-983168	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:bHUiSJ345KLIwL+xD2qH/CJVqL09606	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	intact-crc:3A7C3E8613821637|rigid:MgV07ZcROnlMpbKashh2ZzE39kY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:Q969K3	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-2340642|uniprotkb:Q8NG47|uniprotkb:Q9H6W8|uniprotkb:B7Z933|ensembl:ENSP00000355137	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:rnf34_human(display_long)|uniprotkb:RNF34(gene name)|psi-mi:RNF34(display_short)|uniprotkb:RING finger protein 34(gene name synonym)|uniprotkb:RING finger protein RIFF(gene name synonym)|uniprotkb:FYVE-RING finger protein Momo(gene name synonym)|uniprotkb:Human RING finger homologous to inhibitor of apoptosis protein(gene name synonym)|uniprotkb:Caspases-8 and -10-associated RING finger protein 1(gene name synonym)|uniprotkb:Caspase regulator CARP1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF34(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340648|imex:IM-11696-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_001243787.1|refseq:NP_079402.2|refseq:NP_919247.1|ensembl:ENSG00000170633(gene)|ensembl:ENST00000361234(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035872"(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901797"(negative regulation of signal transduction by p53 class mediator)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000374"(regulation of oxygen metabolic process)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR036361|mint:Q969K3|reactome:R-HSA-6804757|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:pvINlXbJ9UfZbyW4YqRO+HQsCnw9606	intact-crc:4159E19BF3003C56|rigid:99aUZSe7xruAr0huba2cC91xa+4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q8N5U6	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-714023|uniprotkb:Q92550|uniprotkb:Q9NPP8|uniprotkb:Q9ULW4|ensembl:ENSP00000322242	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:rnf10_human(display_long)|uniprotkb:RNF10(gene name)|psi-mi:RNF10(display_short)|uniprotkb:KIAA0262(gene name synonym)|uniprotkb:RIE2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340651|imex:IM-11696-52	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_055683.3|refseq:NP_001317403.1|ensembl:ENSG00000022840(gene)|ensembl:ENST00000325954(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039739|mint:Q8N5U6	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:Bca0Ae456x1eCsdlduoCbn7coUQ9606	intact-crc:2D1551343D69D6CC|rigid:0XZlbL78BCrPJ1FMPEUIn4iXTww	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6ZNA4	uniprotkb:P63279	intact:EBI-2129175|uniprotkb:Q6ZMU2|uniprotkb:Q7L428|uniprotkb:Q7Z346|uniprotkb:Q8N1P9|uniprotkb:Q8WUA3|uniprotkb:Q9NSR1|uniprotkb:Q6P9A4|uniprotkb:C9JUS4|uniprotkb:H0YN55|ensembl:ENSP00000452732|intact:EBI-28970158	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:rn111_human(display_long)|uniprotkb:RNF111(gene name)|psi-mi:RNF111(display_short)|uniprotkb:RING finger protein 111(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Arkadia(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340654|imex:IM-11696-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060080.6|ensembl:ENST00000348370|ensembl:ENSP00000288199|ensembl:ENSP00000452732|ensembl:ENST00000559209|ensembl:ENSP00000453872|ensembl:ENST00000561186|ensembl:ENSP00000453015|refseq:NP_001317260.1|refseq:XP_016877827.1|refseq:XP_006720642.1|refseq:NP_001257459.1|refseq:NP_001257457.1|refseq:NP_001257458.1|ensembl:ENSG00000157450(gene)|ensembl:ENST00000557998(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR029306|rcsb pdb:2KIZ|rcsb pdb:5LG0|rcsb pdb:5LG7|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-5696395|reactome:R-HSA-983168|go:"GO:0032184"(SUMO polymer binding)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:6SY5oMr5u4mnVi+zdRboVljMGa09606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:F7CDDDF1E687DF93|rigid:ePpGGs+3Z0ztMlxVdcXPTIlynHc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BYM8	uniprotkb:P68036	intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym)	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340668|imex:IM-11696-56	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006453.1|refseq:NP_112506.2|ensembl:ENSG00000125826(gene)|ensembl:ENST00000356286(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR026261|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|dip:DIP-47737N	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	intact-crc:DEBA518537414C43|rigid:DKsqshh+tMqO8XSffbRV8d2r5Yg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P68036	uniprotkb:P50876	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	intact:EBI-2340657|uniprotkb:Q585H5|uniprotkb:D6W4Y6|ensembl:ENSP00000321330	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:r144a_human(display_long)|uniprotkb:RNF144A(gene name)|psi-mi:RNF144A(display_short)|uniprotkb:KIAA0161(gene name synonym)|uniprotkb:RNF144(gene name synonym)|uniprotkb:UBCE7IP4(gene name synonym)|uniprotkb:RING finger protein 144A(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 4(gene name synonym)|uniprotkb:UbcM4-interacting protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340662|imex:IM-11696-54	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	refseq:NP_055561.2|refseq:XP_016860885.1|refseq:XP_005246257.1|refseq:XP_005246259.1|refseq:XP_016860886.1|ensembl:ENSG00000151692(gene)|ensembl:ENST00000320892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031127|interpro:IPR044066|mint:P50876|rcsb pdb:1WIM|rcsb pdb:6L99|reactome:R-HSA-8866654	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	rogid:i2Ls6RkN4dTdPkBoso7ZDyIqi+g9606	intact-crc:2D82F03753E092C7|rigid:3cq7tj7iOiM6dieGiI2T+NuA2wM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P68036	uniprotkb:O95376	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	intact:EBI-711158|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9|ensembl:ENSP00000348769|ensembl:ENSP00000403222	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340665|imex:IM-11696-55	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|ensembl:ENSG00000177479(gene)|ensembl:ENST00000356401(transcript)|ensembl:ENST00000449376(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|refseq:XP_016861020.1|refseq:XP_016861021.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	intact-crc:7EA29E278DB619D3|rigid:fxvoJldDk1ywiJg/lEXiNgn6mP8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O94941	uniprotkb:P68036	intact:EBI-751901|uniprotkb:Q6IAR5|uniprotkb:Q86X87|uniprotkb:Q9H4J2|ensembl:ENSP00000217173	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	psi-mi:rnf37_human(display_long)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 5(gene name synonym)|uniprotkb:U-box domain-containing protein 5(gene name synonym)|uniprotkb:UBOX5(gene name)|psi-mi:UBOX5(display_short)|uniprotkb:KIAA0860(gene name synonym)|uniprotkb:RNF37(gene name synonym)|uniprotkb:UBCE7IP5(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF37(gene name synonym)|uniprotkb:UIP5(gene name synonym)|uniprotkb:UbcM4-interacting protein 5(gene name synonym)	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340671|imex:IM-11696-390	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055763.1|refseq:NP_955447.1|ensembl:ENSG00000185019(gene)|ensembl:ENST00000217173(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039847|interpro:IPR039925|reactome:R-HSA-983168	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:bHUiSJ345KLIwL+xD2qH/CJVqL09606	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	intact-crc:E185F71E20AAAEB8|rigid:Sk8hsQ6cw6cOUR38Bb6F88T5z34	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P68036	uniprotkb:Q96EQ8	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340674|imex:IM-11696-391	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	intact-crc:F0E921849DF409A7|rigid:uM05WosGxcNY8/Bw23G+nx347aI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P98170	uniprotkb:P61088	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340689|imex:IM-11696-394	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	intact-crc:0943E91597DE2DE5|rigid:FmuIDEvRIJL0Zg+Djd5bArd6dCY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P68036	uniprotkb:Q8IZP6	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	intact:EBI-2340677|uniprotkb:Q96QY9|uniprotkb:Q8WWF9|ensembl:ENSP00000267291	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:r113b_human(display_long)|uniprotkb:RNF113B(gene name)|psi-mi:RNF113B(display_short)|uniprotkb:RNF161(gene name synonym)|uniprotkb:ZNF183L1(gene name synonym)|uniprotkb:Zinc finger protein 183-like 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340683|imex:IM-11696-392	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	refseq:NP_849192.1|ensembl:ENSG00000139797(gene)|ensembl:ENST00000267291(transcript)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036855|interpro:IPR039971|rcsb pdb:2CSY	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	rogid:v4QnmiYlYp4zInfMBKQQxTUnrd89606	intact-crc:5E54926D1ACCAF58|rigid:2Vxz6iNmTR6Y9mJAadPnMQgKhsI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P68036	uniprotkb:Q7Z419	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	intact:EBI-2129982|uniprotkb:B3KUA8|uniprotkb:Q5TB85|uniprotkb:Q6P4Q0|uniprotkb:Q8N3R7|uniprotkb:Q9BX38|uniprotkb:B4DZI2|ensembl:ENSP00000259939	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:r144b_human(display_long)|uniprotkb:RNF144B(gene name)|psi-mi:RNF144B(display_short)|uniprotkb:IBRDC2(gene name synonym)|uniprotkb:P53RFP(gene name synonym)|uniprotkb:RING finger protein 144B(gene name synonym)|uniprotkb:IBR domain-containing protein 2(gene name synonym)|uniprotkb:p53-inducible RING finger protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340686|imex:IM-11696-393	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	refseq:NP_877434.2|dip:DIP-43771N|ensembl:ENSG00000137393(gene)|ensembl:ENST00000259939(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	rogid:Ep53jYpmEeClpBZYNkPKrQgy/0A9606	intact-crc:7D40FCFC5D41560E|rigid:7//I3OzVSImGpJLQpgQ6qHN441w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15344	uniprotkb:P61088	intact:EBI-2340316|uniprotkb:Q9BZX5|uniprotkb:O75361|uniprotkb:B2RCG2|ensembl:ENSP00000312678|ensembl:ENSP00000370156|ensembl:ENSP00000370157|ensembl:ENSP00000370162|ensembl:ENSP00000370164|ensembl:ENSP00000414521	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	psi-mi:tri18_human(display_long)|uniprotkb:MID1(gene name)|psi-mi:MID1(display_short)|uniprotkb:FXY(gene name synonym)|uniprotkb:RNF59(gene name synonym)|uniprotkb:TRIM18(gene name synonym)|uniprotkb:XPRF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 18(gene name synonym)|uniprotkb:Putative transcription factor XPRF(gene name synonym)|uniprotkb:Midin(gene name synonym)|uniprotkb:RING finger protein 59(gene name synonym)|uniprotkb:RING finger protein Midline-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Midline-1(gene name synonym)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340692|imex:IM-11696-395	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000372.1|refseq:NP_001092094.1|refseq:NP_001180206.1|refseq:NP_001180207.1|refseq:NP_001180208.1|refseq:NP_001180209.1|refseq:NP_001180210.1|refseq:NP_150632.1|refseq:NP_001334662.1|refseq:XP_016885025.1|refseq:XP_016885029.1|ensembl:ENSG00000101871(gene)|ensembl:ENST00000317552(transcript)|ensembl:ENST00000380779(transcript)|ensembl:ENST00000380780(transcript)|ensembl:ENST00000380785(transcript)|ensembl:ENST00000380787(transcript)|ensembl:ENST00000453318(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016740"(transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003649(B-box, C-terminal)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR027727|interpro:IPR036116|interpro:IPR040859|interpro:IPR043136|rcsb pdb:2DQ5|rcsb pdb:2FFW|rcsb pdb:2JUN|rcsb pdb:5IM8|reactome:R-HSA-877300	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:NGlMGyFT7GEcrzVR/Iw4LitMBig9606	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	intact-crc:DB9056A049A611DC|rigid:Wi5aMV7jEVBBx82K8ah76zer5Bg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q8IUQ4	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-747107|uniprotkb:O43269|uniprotkb:Q49A58|uniprotkb:A0FKF3|uniprotkb:Q92880|ensembl:ENSP00000369343|ensembl:ENSP00000378214|ensembl:ENSP00000456421	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:siah1_human(display_long)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340695|imex:IM-11696-396	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	refseq:XP_006721309.1|refseq:NP_001006611.1|refseq:NP_003022.3|refseq:XP_011521581.1|ensembl:ENST00000380006(transcript)|ensembl:ENST00000394725(transcript)|ensembl:ENST00000568007(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|mint:Q8IUQ4|rcsb pdb:2A25|rcsb pdb:4C9Z|rcsb pdb:4CA1|rcsb pdb:4I7B|rcsb pdb:4I7C|rcsb pdb:4I7D|rcsb pdb:4X3G|rcsb pdb:5WZZ|reactome:R-HSA-373752|reactome:R-HSA-977225|reactome:R-HSA-983168|ensembl:ENSG00000196470(gene)|dip:DIP-35684N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid:O6+z1g9K1ij87Xgo5/Ykl5Q3vUQ9606	intact-crc:F724C8F9DD299B9D|rigid:F/R6wuW54YzxVE1GS4MYR0f2C60	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y4K3	uniprotkb:P61088	intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|ensembl:ENSP00000337853|ensembl:ENSP00000433623|uniprotkb:D3DR16	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340698|imex:IM-11696-397	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004611.1|refseq:NP_665802.1|ensembl:ENSG00000175104(gene)|ensembl:ENST00000348124(transcript)|ensembl:ENST00000526995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|go:"GO:0070534"(protein K63-linked ubiquitination)|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|go:"GO:0070555"(response to interleukin-1)|rcsb pdb:7L3L|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|go:"GO:0071222"(cellular response to lipopolysaccharide)|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-975871|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|dip:DIP-27515N	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	intact-crc:7BF48109078FE329|rigid:rTuhyeFjBYVdR/fADCmNcLvYga0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q13064	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-2340269|ensembl:ENSP00000313881	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340701|imex:IM-11696-398	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606	intact-crc:7E01FEB87084A171|rigid:ns3CiLnjIhHhab+sXDwPpC2HKyY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q9BYM8	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340710|imex:IM-11696-57	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	refseq:NP_006453.1|refseq:NP_112506.2|ensembl:ENSG00000125826(gene)|ensembl:ENST00000356286(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR026261|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|dip:DIP-47737N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606	intact-crc:95D42C0C7E632297|rigid:hFZQ73w9Ud02C3YYuNLyfwSMrp8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76064	uniprotkb:P61088	intact:EBI-373337|uniprotkb:Q53H16|uniprotkb:Q5NKW5|uniprotkb:A6NN24|uniprotkb:A8MYC0|uniprotkb:B4DPG0|ensembl:ENSP00000362578	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	psi-mi:rnf8_human(display_long)|uniprotkb:RNF8(gene name)|psi-mi:RNF8(display_short)|uniprotkb:KIAA0646(gene name synonym)|uniprotkb:RING finger protein 8(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF8(gene name synonym)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340704|imex:IM-11696-399	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003949.1|refseq:NP_898901.1|ensembl:ENST00000373479(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007286"(spermatid development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|mint:O76064|rcsb pdb:2CSW|rcsb pdb:2PIE|rcsb pdb:4AYC|rcsb pdb:4ORH|rcsb pdb:4WHV|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|interpro:IPR017907|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043486"(histone exchange)|go:"GO:0045190"(isotype switching)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051301"(cell division)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070535"(histone H2A K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017335(E3 ubiquitin ligase, RNF8)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|ensembl:ENSG00000112130(gene)|dip:DIP-31265N	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:nsYlZhRT5wsltOEjHh1l815IphQ9606	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	intact-crc:353109AB6C7C37DC|rigid:C/mrWxJ3IhyXYX7hzgdm7/1cA5Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86Y13	uniprotkb:P61088	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340707|imex:IM-11696-400	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	intact-crc:BD9EFDD38EC0F068|rigid:SbISQGetu0odgk9ZROwA5X/FSuY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q13049	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340713|imex:IM-11696-58	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606	intact-crc:199687CFE5CD9384|rigid:DffqeYioXyAc6XRU79ZCzqZb6u8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q9Y3C5	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-396669|intact:EBI-2129167|uniprotkb:A8KAI2|uniprotkb:Q5T7R8|ensembl:ENSP00000242719	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:rnf11_human(display_long)|uniprotkb:CGI-123(orf name)|uniprotkb:RNF11(gene name)|psi-mi:RNF11(display_short)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340716|imex:IM-11696-59	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	refseq:NP_055187.1|ensembl:ENSP00000242719|ensembl:ENSG00000123091(gene)|ensembl:ENST00000242719(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042981|mint:Q9Y3C5	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid:Uj0YAf/t+AdYbMd6fgQ8hVKoP0w9606	intact-crc:D7D59DE737B0D363|rigid:htUTfVJJEz8FqXAR5HFYw+BlJXg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HBD1	uniprotkb:P61088	intact:EBI-2340719|uniprotkb:Q8N3D6|uniprotkb:Q9H5J2|uniprotkb:Q9NWN9|uniprotkb:Q9NXE1|uniprotkb:Q86ST6|uniprotkb:Q5JPD7|uniprotkb:Q9HBD2|uniprotkb:Q96F27|uniprotkb:Q4VXB1|ensembl:ENSP00000349783|ensembl:ENSP00000362774	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	psi-mi:rc3h2_human(display_long)|uniprotkb:RC3H2(gene name)|psi-mi:RC3H2(display_short)|uniprotkb:MNAB(gene name synonym)|uniprotkb:RNF164(gene name synonym)|uniprotkb:Membrane-associated nucleic acid-binding protein(gene name synonym)|uniprotkb:RING finger protein 164(gene name synonym)|uniprotkb:RING finger and CCCH-type zinc finger domain-containing protein 2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Roquin-2(gene name synonym)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340732|imex:IM-11696-60	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094058.1|refseq:NP_061323.2|ensembl:ENSG00000056586(gene)|ensembl:ENST00000357244(transcript)|ensembl:ENST00000373670(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009986"(cell surface)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0046872"(metal ion binding)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060173"(limb development)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032670|interpro:IPR036855|interpro:IPR041523|rcsb pdb:4Z30|rcsb pdb:4Z31|rcsb pdb:4ZLC|rcsb pdb:4ZLD	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:UThBG9DsQJ7jfnx9xkCBkBKkaT89606	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	intact-crc:F3A444A4F718B13C|rigid:Yo4B4A3REBxnLgEfuCwLqp1BuQA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q8ND25	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340735|imex:IM-11696-61	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	intact-crc:DA209B374B06DE54|rigid:qTf7IGTbFoOBDbMBjLDpRO67mzk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13404	uniprotkb:O94941	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-751901|uniprotkb:Q6IAR5|uniprotkb:Q86X87|uniprotkb:Q9H4J2|ensembl:ENSP00000217173	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:rnf37_human(display_long)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 5(gene name synonym)|uniprotkb:U-box domain-containing protein 5(gene name synonym)|uniprotkb:UBOX5(gene name)|psi-mi:UBOX5(display_short)|uniprotkb:KIAA0860(gene name synonym)|uniprotkb:RNF37(gene name synonym)|uniprotkb:UBCE7IP5(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF37(gene name synonym)|uniprotkb:UIP5(gene name synonym)|uniprotkb:UbcM4-interacting protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340744|imex:IM-11696-64	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	refseq:NP_055763.1|refseq:NP_955447.1|ensembl:ENSG00000185019(gene)|ensembl:ENST00000217173(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039847|interpro:IPR039925|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:bHUiSJ345KLIwL+xD2qH/CJVqL09606	intact-crc:09F711E980DE5611|rigid:hVf9BVAZnC2NyPZbo5lo5mFun4I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13404	uniprotkb:O15344	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-2340316|uniprotkb:Q9BZX5|uniprotkb:O75361|uniprotkb:B2RCG2|ensembl:ENSP00000312678|ensembl:ENSP00000370156|ensembl:ENSP00000370157|ensembl:ENSP00000370162|ensembl:ENSP00000370164|ensembl:ENSP00000414521	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:tri18_human(display_long)|uniprotkb:MID1(gene name)|psi-mi:MID1(display_short)|uniprotkb:FXY(gene name synonym)|uniprotkb:RNF59(gene name synonym)|uniprotkb:TRIM18(gene name synonym)|uniprotkb:XPRF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 18(gene name synonym)|uniprotkb:Putative transcription factor XPRF(gene name synonym)|uniprotkb:Midin(gene name synonym)|uniprotkb:RING finger protein 59(gene name synonym)|uniprotkb:RING finger protein Midline-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Midline-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340738|imex:IM-11696-62	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	refseq:NP_000372.1|refseq:NP_001092094.1|refseq:NP_001180206.1|refseq:NP_001180207.1|refseq:NP_001180208.1|refseq:NP_001180209.1|refseq:NP_001180210.1|refseq:NP_150632.1|refseq:NP_001334662.1|refseq:XP_016885025.1|refseq:XP_016885029.1|ensembl:ENSG00000101871(gene)|ensembl:ENST00000317552(transcript)|ensembl:ENST00000380779(transcript)|ensembl:ENST00000380780(transcript)|ensembl:ENST00000380785(transcript)|ensembl:ENST00000380787(transcript)|ensembl:ENST00000453318(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016740"(transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003649(B-box, C-terminal)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR027727|interpro:IPR036116|interpro:IPR040859|interpro:IPR043136|rcsb pdb:2DQ5|rcsb pdb:2FFW|rcsb pdb:2JUN|rcsb pdb:5IM8|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:NGlMGyFT7GEcrzVR/Iw4LitMBig9606	intact-crc:C71766967897B2B7|rigid:MMkNJQR0fZhcR/lh7dtxtBY7vbs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBS8	uniprotkb:Q13404	intact:EBI-2130308|uniprotkb:B7ZLV2|uniprotkb:A0AV26|uniprotkb:A6NMR2|uniprotkb:B3KN72|uniprotkb:O94793|uniprotkb:Q6IBV0|uniprotkb:A8MTW5|uniprotkb:D3DQE4|ensembl:ENSP00000324956|ensembl:ENSP00000348462|ensembl:ENSP00000378027|ensembl:ENSP00000378028	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	psi-mi:rnf14_human(display_long)|uniprotkb:RNF14(gene name)|psi-mi:RNF14(display_short)|uniprotkb:ARA54(gene name synonym)|uniprotkb:RING finger protein 14(gene name synonym)|uniprotkb:Androgen receptor-associated protein 54(gene name synonym)|uniprotkb:Triad2 protein(gene name synonym)|uniprotkb:HFB30(gene name synonym)|uniprotkb:HRIHFB2038(orf name)	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340741|imex:IM-11696-63	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011536016.1|refseq:NP_001188294.1|refseq:NP_004281.1|refseq:NP_899645.1|refseq:NP_899646.1|refseq:NP_899647.1|refseq:NP_899648.1|refseq:XP_016865559.1|refseq:XP_016865560.1|refseq:XP_016865561.1|refseq:XP_005268593.1|refseq:XP_005268594.1|refseq:XP_005268596.1|refseq:XP_005268597.1|refseq:XP_005268598.1|ensembl:ENSG00000013561(gene)|ensembl:ENST00000347642(transcript)|ensembl:ENST00000356143(transcript)|ensembl:ENST00000394519(transcript)|ensembl:ENST00000394520(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017907|interpro:IPR031127|interpro:IPR031128|interpro:IPR044066|mint:Q9UBS8|reactome:R-HSA-983168	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:zCNZ6kHw7XNUvpVBRQSgZ7ffJ9U9606	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	intact-crc:FDC8E8FF03286306|rigid:W7Smgb2DblqQZw8GdOtkbaYkRIg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZR9	uniprotkb:Q13404	intact:EBI-2340370|uniprotkb:Q9C028|uniprotkb:A6NI31|intact:EBI-2796718|ensembl:ENSP00000496301	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	psi-mi:trim8_human(display_long)|uniprotkb:Tripartite motif-containing protein 8(gene name synonym)|uniprotkb:TRIM8(gene name)|psi-mi:TRIM8(display_short)|uniprotkb:GERP(gene name synonym)|uniprotkb:RNF27(gene name synonym)|uniprotkb:RING finger protein 27(gene name synonym)|uniprotkb:Glioblastoma-expressed RING finger protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM8(gene name synonym)	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340747|imex:IM-11696-65	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112174.2|ensembl:ENSG00000171206(gene)|ensembl:ENST00000643721(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0016740"(transferase activity)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902187"|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-877300	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:WFqavXVFV3/XbJSA2k06Pg9Eaag9606	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	intact-crc:F6FFAA1A2D0AE81F|rigid:2ASrRTfUaeHtPizAPl/RozZP7SI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13404	uniprotkb:Q8ND25	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340750|imex:IM-11696-66	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	intact-crc:3156AA0595ADFB51|rigid:Q25QLoakkdeYUN6PXBahrtVkag4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14933	uniprotkb:Q9BYM8	intact:EBI-2129974|uniprotkb:A6NDM6|uniprotkb:Q8N5D8|uniprotkb:A8MY53|uniprotkb:Q9UEZ0|ensembl:ENSP00000287156	intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632	psi-mi:ub2l6_human(display_long)|uniprotkb:UBE2L6(gene name)|psi-mi:UBE2L6(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L6(gene name synonym)|uniprotkb:Ubiquitin carrier protein L6(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:Retinoic acid-induced gene B protein(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L6(gene name synonym)	psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340759|imex:IM-11696-69	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004214.1|refseq:NP_937826.1|ensembl:ENSP00000287156|ensembl:ENST00000340573|ensembl:ENSP00000341980|dip:DIP-41477N|ensembl:ENSG00000156587(gene)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:O14933|rcsb pdb:1WZV|rcsb pdb:1WZW|rcsb pdb:2KJH|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|ensembl:ENST00000287156(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|reactome:R-HSA-936440|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032020"(ISG15-protein conjugation)	refseq:NP_006453.1|refseq:NP_112506.2|ensembl:ENSG00000125826(gene)|ensembl:ENST00000356286(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR026261|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|dip:DIP-47737N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:18K+ReSJfSpKRvnLuED+kPB3beY9606	rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606	intact-crc:E0C1131E8529DD47|rigid:wIo/4OrbZ6Ug/nxawwJxDV/FN/8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P50876	uniprotkb:O14933	intact:EBI-2340657|uniprotkb:Q585H5|uniprotkb:D6W4Y6|ensembl:ENSP00000321330	intact:EBI-2129974|uniprotkb:A6NDM6|uniprotkb:Q8N5D8|uniprotkb:A8MY53|uniprotkb:Q9UEZ0|ensembl:ENSP00000287156	psi-mi:r144a_human(display_long)|uniprotkb:RNF144A(gene name)|psi-mi:RNF144A(display_short)|uniprotkb:KIAA0161(gene name synonym)|uniprotkb:RNF144(gene name synonym)|uniprotkb:UBCE7IP4(gene name synonym)|uniprotkb:RING finger protein 144A(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 4(gene name synonym)|uniprotkb:UbcM4-interacting protein 4(gene name synonym)	psi-mi:ub2l6_human(display_long)|uniprotkb:UBE2L6(gene name)|psi-mi:UBE2L6(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L6(gene name synonym)|uniprotkb:Ubiquitin carrier protein L6(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:Retinoic acid-induced gene B protein(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340753|imex:IM-11696-67	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055561.2|refseq:XP_016860885.1|refseq:XP_005246257.1|refseq:XP_005246259.1|refseq:XP_016860886.1|ensembl:ENSG00000151692(gene)|ensembl:ENST00000320892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031127|interpro:IPR044066|mint:P50876|rcsb pdb:1WIM|rcsb pdb:6L99|reactome:R-HSA-8866654	refseq:NP_004214.1|refseq:NP_937826.1|ensembl:ENSP00000287156|ensembl:ENST00000340573|ensembl:ENSP00000341980|dip:DIP-41477N|ensembl:ENSG00000156587(gene)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:O14933|rcsb pdb:1WZV|rcsb pdb:1WZW|rcsb pdb:2KJH|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|ensembl:ENST00000287156(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|reactome:R-HSA-936440|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032020"(ISG15-protein conjugation)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:i2Ls6RkN4dTdPkBoso7ZDyIqi+g9606	rogid:18K+ReSJfSpKRvnLuED+kPB3beY9606	intact-crc:092CA6E1FD7728A8|rigid:VAoYWbDPCUmbOMmh3JQg+8oK4+w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95376	uniprotkb:O14933	intact:EBI-711158|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9|ensembl:ENSP00000348769|ensembl:ENSP00000403222	intact:EBI-2129974|uniprotkb:A6NDM6|uniprotkb:Q8N5D8|uniprotkb:A8MY53|uniprotkb:Q9UEZ0|ensembl:ENSP00000287156	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym)	psi-mi:ub2l6_human(display_long)|uniprotkb:UBE2L6(gene name)|psi-mi:UBE2L6(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L6(gene name synonym)|uniprotkb:Ubiquitin carrier protein L6(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:Retinoic acid-induced gene B protein(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340756|imex:IM-11696-68	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|ensembl:ENSG00000177479(gene)|ensembl:ENST00000356401(transcript)|ensembl:ENST00000449376(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|refseq:XP_016861020.1|refseq:XP_016861021.1	refseq:NP_004214.1|refseq:NP_937826.1|ensembl:ENSP00000287156|ensembl:ENST00000340573|ensembl:ENSP00000341980|dip:DIP-41477N|ensembl:ENSG00000156587(gene)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:O14933|rcsb pdb:1WZV|rcsb pdb:1WZW|rcsb pdb:2KJH|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|ensembl:ENST00000287156(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|reactome:R-HSA-936440|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032020"(ISG15-protein conjugation)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	rogid:18K+ReSJfSpKRvnLuED+kPB3beY9606	intact-crc:0678AB7EAB34B07F|rigid:IxQonLEzJCGE0POmUpJz61TIxEg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14933	uniprotkb:Q8N9I9	intact:EBI-2129974|uniprotkb:A6NDM6|uniprotkb:Q8N5D8|uniprotkb:A8MY53|uniprotkb:Q9UEZ0|ensembl:ENSP00000287156	intact:EBI-2340258|uniprotkb:Q8NDS8|uniprotkb:Q8NAU6|uniprotkb:Q53ZZ2|ensembl:ENSP00000338050|ensembl:ENSP00000447873|ensembl:ENSP00000449294	psi-mi:ub2l6_human(display_long)|uniprotkb:UBE2L6(gene name)|psi-mi:UBE2L6(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L6(gene name synonym)|uniprotkb:Ubiquitin carrier protein L6(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:Retinoic acid-induced gene B protein(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L6(gene name synonym)	psi-mi:dtx3_human(display_long)|uniprotkb:DTX3(gene name)|psi-mi:DTX3(display_short)|uniprotkb:RNF154(gene name synonym)|uniprotkb:RING finger protein 154(gene name synonym)|uniprotkb:Protein deltex-3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340768|imex:IM-11696-72	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004214.1|refseq:NP_937826.1|ensembl:ENSP00000287156|ensembl:ENST00000340573|ensembl:ENSP00000341980|dip:DIP-41477N|ensembl:ENSG00000156587(gene)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:O14933|rcsb pdb:1WZV|rcsb pdb:1WZW|rcsb pdb:2KJH|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|ensembl:ENST00000287156(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|reactome:R-HSA-936440|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032020"(ISG15-protein conjugation)	refseq:NP_001273174.1|refseq:NP_001273175.1|refseq:XP_011536324.1|refseq:NP_848597.1|refseq:XP_005268754.1|refseq:XP_005268755.1|refseq:XP_005268757.1|refseq:XP_005268760.1|ensembl:ENSG00000178498(gene)|ensembl:ENST00000337737(transcript)|ensembl:ENST00000548198(transcript)|ensembl:ENST00000548804(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:18K+ReSJfSpKRvnLuED+kPB3beY9606	rogid:Ma7JBhgMdFofCeWESbf8h1iLAHY9606	intact-crc:24EDE6A19A56149C|rigid:R5oVXEK/kJVegIrkanMKMqAWBc0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14933	uniprotkb:Q96EQ8	intact:EBI-2129974|uniprotkb:A6NDM6|uniprotkb:Q8N5D8|uniprotkb:A8MY53|uniprotkb:Q9UEZ0|ensembl:ENSP00000287156	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:ub2l6_human(display_long)|uniprotkb:UBE2L6(gene name)|psi-mi:UBE2L6(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L6(gene name synonym)|uniprotkb:Ubiquitin carrier protein L6(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:Retinoic acid-induced gene B protein(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L6(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340762|imex:IM-11696-70	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004214.1|refseq:NP_937826.1|ensembl:ENSP00000287156|ensembl:ENST00000340573|ensembl:ENSP00000341980|dip:DIP-41477N|ensembl:ENSG00000156587(gene)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:O14933|rcsb pdb:1WZV|rcsb pdb:1WZW|rcsb pdb:2KJH|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|ensembl:ENST00000287156(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|reactome:R-HSA-936440|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032020"(ISG15-protein conjugation)	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:18K+ReSJfSpKRvnLuED+kPB3beY9606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	intact-crc:CE92631F2F9C98A3|rigid:iF09gTg942kM+OSUyExkNIs91DM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14933	uniprotkb:Q6Q0C0	intact:EBI-2129974|uniprotkb:A6NDM6|uniprotkb:Q8N5D8|uniprotkb:A8MY53|uniprotkb:Q9UEZ0|ensembl:ENSP00000287156	intact:EBI-307556|uniprotkb:Q9H073|ensembl:ENSP00000318944	psi-mi:ub2l6_human(display_long)|uniprotkb:UBE2L6(gene name)|psi-mi:UBE2L6(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L6(gene name synonym)|uniprotkb:Ubiquitin carrier protein L6(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:Retinoic acid-induced gene B protein(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L6(gene name synonym)	psi-mi:traf7_human(display_long)|uniprotkb:TRAF7(gene name)|psi-mi:TRAF7(display_short)|uniprotkb:TNF receptor-associated factor 7(gene name synonym)|uniprotkb:RING finger and WD repeat-containing protein 1(gene name synonym)|uniprotkb:RING finger protein 119(gene name synonym)|uniprotkb:RFWD1(gene name synonym)|uniprotkb:RNF119(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340765|imex:IM-11696-71	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004214.1|refseq:NP_937826.1|ensembl:ENSP00000287156|ensembl:ENST00000340573|ensembl:ENSP00000341980|dip:DIP-41477N|ensembl:ENSG00000156587(gene)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:O14933|rcsb pdb:1WZV|rcsb pdb:1WZW|rcsb pdb:2KJH|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|ensembl:ENST00000287156(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|reactome:R-HSA-936440|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032020"(ISG15-protein conjugation)	refseq:NP_115647.2|ensembl:ENSG00000131653(gene)|ensembl:ENST00000326181(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017907|interpro:IPR019775|interpro:IPR020472|interpro:IPR027370|interpro:IPR036322|mint:Q6Q0C0|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:18K+ReSJfSpKRvnLuED+kPB3beY9606	rogid:46dtsS1OairncB0fnINSW1aY2789606	intact-crc:D580937B8604426A|rigid:A6TsrHPl4RI5+uduVHfcyjwfpAA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14933	uniprotkb:Q7Z419	intact:EBI-2129974|uniprotkb:A6NDM6|uniprotkb:Q8N5D8|uniprotkb:A8MY53|uniprotkb:Q9UEZ0|ensembl:ENSP00000287156	intact:EBI-2129982|uniprotkb:B3KUA8|uniprotkb:Q5TB85|uniprotkb:Q6P4Q0|uniprotkb:Q8N3R7|uniprotkb:Q9BX38|uniprotkb:B4DZI2|ensembl:ENSP00000259939	psi-mi:ub2l6_human(display_long)|uniprotkb:UBE2L6(gene name)|psi-mi:UBE2L6(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L6(gene name synonym)|uniprotkb:Ubiquitin carrier protein L6(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:Retinoic acid-induced gene B protein(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L6(gene name synonym)	psi-mi:r144b_human(display_long)|uniprotkb:RNF144B(gene name)|psi-mi:RNF144B(display_short)|uniprotkb:IBRDC2(gene name synonym)|uniprotkb:P53RFP(gene name synonym)|uniprotkb:RING finger protein 144B(gene name synonym)|uniprotkb:IBR domain-containing protein 2(gene name synonym)|uniprotkb:p53-inducible RING finger protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340771|imex:IM-11696-73	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004214.1|refseq:NP_937826.1|ensembl:ENSP00000287156|ensembl:ENST00000340573|ensembl:ENSP00000341980|dip:DIP-41477N|ensembl:ENSG00000156587(gene)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:O14933|rcsb pdb:1WZV|rcsb pdb:1WZW|rcsb pdb:2KJH|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|ensembl:ENST00000287156(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|reactome:R-HSA-936440|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032020"(ISG15-protein conjugation)	refseq:NP_877434.2|dip:DIP-43771N|ensembl:ENSG00000137393(gene)|ensembl:ENST00000259939(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:18K+ReSJfSpKRvnLuED+kPB3beY9606	rogid:Ep53jYpmEeClpBZYNkPKrQgy/0A9606	intact-crc:433BBE67EF29C70A|rigid:rF9X1iRAe5GpVx+Meb34bEAhFwo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99496	uniprotkb:Q969T4	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340774|imex:IM-11696-74	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	intact-crc:162CCC1EE0832341|rigid:PaO3Q+jy9EoQBmRQQM+Vok3a2Nc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:Q99942	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340777|imex:IM-11696-75	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606	intact-crc:A1E69511DB187445|rigid:5io8H27OLvibjV1lXZV+/WR3OhE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86Y13	uniprotkb:Q969T4	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340780|imex:IM-11696-76	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	intact-crc:2190BFD091F50FC7|rigid:el/HZ/qMyEbDeqvIyE/1ehhSpHw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:Q8N5U6	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-714023|uniprotkb:Q92550|uniprotkb:Q9NPP8|uniprotkb:Q9ULW4|ensembl:ENSP00000322242	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:rnf10_human(display_long)|uniprotkb:RNF10(gene name)|psi-mi:RNF10(display_short)|uniprotkb:KIAA0262(gene name synonym)|uniprotkb:RIE2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340783|imex:IM-11696-77	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_055683.3|refseq:NP_001317403.1|ensembl:ENSG00000022840(gene)|ensembl:ENST00000325954(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039739|mint:Q8N5U6	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:Bca0Ae456x1eCsdlduoCbn7coUQ9606	intact-crc:C8F1518FC89BD5AF|rigid:u9T+AImF0klw34z6Hsj2zWqNEUs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:Q9Y3C5	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-396669|intact:EBI-2129167|uniprotkb:A8KAI2|uniprotkb:Q5T7R8|ensembl:ENSP00000242719	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:rnf11_human(display_long)|uniprotkb:CGI-123(orf name)|uniprotkb:RNF11(gene name)|psi-mi:RNF11(display_short)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340786|imex:IM-11696-78	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_055187.1|ensembl:ENSP00000242719|ensembl:ENSG00000123091(gene)|ensembl:ENST00000242719(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042981|mint:Q9Y3C5	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:Uj0YAf/t+AdYbMd6fgQ8hVKoP0w9606	intact-crc:A5DC3CD1ECFBA51E|rigid:CSXV58n1fYSVxW+HXDmivYkkIuU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BH1	uniprotkb:Q969T4	intact:EBI-2129220|uniprotkb:A8K0D6|uniprotkb:Q9H874|uniprotkb:Q53HQ5|ensembl:ENSP00000295704	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	psi-mi:rnf25_human(display_long)|uniprotkb:RNF25(gene name)|psi-mi:RNF25(display_short)|uniprotkb:RING finger protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF25(gene name synonym)	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340795|imex:IM-11696-81	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071898.2|dip:DIP-29063N|ensembl:ENSG00000163481(gene)|ensembl:ENST00000295704(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR039133|rcsb pdb:2DAY|rcsb pdb:2DMF|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|reactome:R-HSA-983168	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:YyCN7mH4eng9G05zRci49oJzKO09606	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	intact-crc:D4F8F4A46A60B1A1|rigid:8C+zunClac+BwTi1/OjR70ifXRw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:Q9Y508	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-723587|uniprotkb:Q6N0B0|uniprotkb:B2RDQ9|uniprotkb:B4DWY5|uniprotkb:E1P627|ensembl:ENSP00000244061	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:rn114_human(display_long)|uniprotkb:Zinc finger protein 313(gene name synonym)|uniprotkb:RNF114(gene name)|psi-mi:RNF114(display_short)|uniprotkb:ZNF313(gene name synonym)|uniprotkb:ZNF228(gene name synonym)|uniprotkb:Zinc finger protein 228(gene name synonym)|uniprotkb:RING finger protein 114(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF114(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340789|imex:IM-11696-79	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_061153.1|ensembl:ENSG00000124226(gene)|ensembl:ENST00000244061(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR034734|interpro:IPR042716|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:R1fX8xaGuIhy/M6cLzPeyfJBf649606	intact-crc:D1B7B53C25597B8D|rigid:YaYeuAnLP4dEaMKeTNCa8e4m5w8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:Q9HCM9	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-739510|uniprotkb:Q5STG4|uniprotkb:Q76BL3|uniprotkb:Q8IYT9|uniprotkb:Q96IB6|ensembl:ENSP00000365844|ensembl:ENSP00000373096|ensembl:ENSP00000379796|ensembl:ENSP00000391917|ensembl:ENSP00000397043|ensembl:ENSP00000398355|ensembl:ENSP00000409902|ensembl:ENSP00000411949|ensembl:ENSP00000447835|ensembl:ENSP00000448462|ensembl:ENSP00000448572|ensembl:ENSP00000449272|ensembl:ENSP00000449847|ensembl:ENSP00000450288|uniprotkb:Q5STG3	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:tri39_human(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340792|imex:IM-11696-80	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376656(transcript)|ensembl:ENST00000383602(transcript)|ensembl:ENST00000396547(transcript)|ensembl:ENST00000413715(transcript)|ensembl:ENST00000424575(transcript)|ensembl:ENST00000445206(transcript)|ensembl:ENST00000426469(transcript)|ensembl:ENST00000451715(transcript)|ensembl:ENST00000547030(transcript)|ensembl:ENST00000548002(transcript)|ensembl:ENST00000549841(transcript)|ensembl:ENST00000550282(transcript)|ensembl:ENST00000552337(transcript)|ensembl:ENST00000552520(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035033|interpro:IPR043136|mint:Q9HCM9|rcsb pdb:2DID|rcsb pdb:2DIF|rcsb pdb:2ECJ|reactome:R-HSA-983168|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_067076.2|refseq:NP_742013.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:xMCXGcMTqCjzLQzC53o81S4gqZA9606	intact-crc:FC938D74A1B80426|rigid:8AoSmaaGE+viKLnXKW02UhU3MIo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:Q8ND25	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340798|imex:IM-11696-82	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	intact-crc:04EBFA5FE99BD54A|rigid:sOtQYkUB397Z43i2F10GLy5JvPA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96GF1	uniprotkb:Q969T4	intact:EBI-2340249|uniprotkb:A8K5C1|uniprotkb:A9X3T8|uniprotkb:Q8N900|ensembl:ENSP00000320508|ensembl:ENSP00000427755	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	psi-mi:rn185_human(display_long)|uniprotkb:RNF185(gene name)|psi-mi:RNF185(display_short)|uniprotkb:RING finger protein 185(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF185(gene name synonym)	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340801|imex:IM-11696-83	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001129297.1|refseq:NP_689480.2|ensembl:ENSG00000138942(gene)|ensembl:ENST00000326132(transcript)|ensembl:ENST00000518626(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ivzbt31KPTKL/Rc1Wzs3h80XJac9606	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	intact-crc:C74D3252AFA4E65E|rigid:rEw5+KcUYt6DXWX1NBTdBvvx9sE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:Q8TDB6	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-2340392|uniprotkb:Q5MJP7|uniprotkb:Q53ZZ3|uniprotkb:B3KWH6|ensembl:ENSP00000296161	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:dtx3l_human(display_long)|uniprotkb:DTX3L(gene name)|psi-mi:DTX3L(display_short)|uniprotkb:BBAP(gene name synonym)|uniprotkb:B-lymphoma- and BAL-associated protein(gene name synonym)|uniprotkb:Rhysin-2(gene name synonym)|uniprotkb:Protein deltex-3-like(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3L(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340804|imex:IM-11696-84	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_612144.1|ensembl:ENSG00000163840(gene)|ensembl:ENST00000296161(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0015031"(protein transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:2000646"(positive regulation of receptor catabolic process)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|interpro:IPR042843|rcsb pdb:3PG6|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:d2ctDfd7pj1wRA3HxmyWJ5nL19Y9606	intact-crc:86A6F8A5433AB81D|rigid:tLB5cnK+iyQzmbWtYu/nGw71RF8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:Q9NPD8	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-2130165|uniprotkb:Q2TU36|ensembl:ENSP00000494957	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:ube2t_human(display_long)|uniprotkb:UBE2T(gene name)|psi-mi:UBE2T(display_short)|uniprotkb:Ubiquitin-protein ligase T(gene name synonym)|uniprotkb:Ubiquitin carrier protein T(gene name synonym)|uniprotkb:HSPC150(orf name)|uniprotkb:Cell proliferation-inducing gene 50 protein(gene name synonym)|uniprotkb:PIG50(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme T(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340807|imex:IM-11696-85	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	refseq:NP_054895.1|refseq:NP_001297255.1|dip:DIP-52740N|ensembl:ENSG00000077152(gene)|ensembl:ENST00000646651(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YH2|rcsb pdb:4CCG|rcsb pdb:5NGZ|rcsb pdb:5OJJ|rcsb pdb:6R75|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|reactome:R-HSA-8866652	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:hKFqKCWzIhcGshB1ut+mTTSwxbQ9606	intact-crc:078F632B19577DA8|rigid:eIY18AbXACiM7bkbxlLyOahcaXo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NPD8	uniprotkb:O95376	intact:EBI-2130165|uniprotkb:Q2TU36|ensembl:ENSP00000494957	intact:EBI-711158|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9|ensembl:ENSP00000348769|ensembl:ENSP00000403222	psi-mi:ube2t_human(display_long)|uniprotkb:UBE2T(gene name)|psi-mi:UBE2T(display_short)|uniprotkb:Ubiquitin-protein ligase T(gene name synonym)|uniprotkb:Ubiquitin carrier protein T(gene name synonym)|uniprotkb:HSPC150(orf name)|uniprotkb:Cell proliferation-inducing gene 50 protein(gene name synonym)|uniprotkb:PIG50(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme T(gene name synonym)	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340810|imex:IM-11696-86	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054895.1|refseq:NP_001297255.1|dip:DIP-52740N|ensembl:ENSG00000077152(gene)|ensembl:ENST00000646651(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YH2|rcsb pdb:4CCG|rcsb pdb:5NGZ|rcsb pdb:5OJJ|rcsb pdb:6R75|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|reactome:R-HSA-8866652	refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|ensembl:ENSG00000177479(gene)|ensembl:ENST00000356401(transcript)|ensembl:ENST00000449376(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|refseq:XP_016861020.1|refseq:XP_016861021.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hKFqKCWzIhcGshB1ut+mTTSwxbQ9606	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	intact-crc:CA39CF3CDC02E8C1|rigid:akMzwl5BR9JEhDm1I+r1PNVebVQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99496	uniprotkb:Q9Y2X8	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340819|imex:IM-11696-89	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:A16A25737E2A9678|rigid:MWquzFxri6jhQMXA5xFt79s2zQ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:O15344	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-2340316|uniprotkb:Q9BZX5|uniprotkb:O75361|uniprotkb:B2RCG2|ensembl:ENSP00000312678|ensembl:ENSP00000370156|ensembl:ENSP00000370157|ensembl:ENSP00000370162|ensembl:ENSP00000370164|ensembl:ENSP00000414521	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:tri18_human(display_long)|uniprotkb:MID1(gene name)|psi-mi:MID1(display_short)|uniprotkb:FXY(gene name synonym)|uniprotkb:RNF59(gene name synonym)|uniprotkb:TRIM18(gene name synonym)|uniprotkb:XPRF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 18(gene name synonym)|uniprotkb:Putative transcription factor XPRF(gene name synonym)|uniprotkb:Midin(gene name synonym)|uniprotkb:RING finger protein 59(gene name synonym)|uniprotkb:RING finger protein Midline-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Midline-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340816|imex:IM-11696-88	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_000372.1|refseq:NP_001092094.1|refseq:NP_001180206.1|refseq:NP_001180207.1|refseq:NP_001180208.1|refseq:NP_001180209.1|refseq:NP_001180210.1|refseq:NP_150632.1|refseq:NP_001334662.1|refseq:XP_016885025.1|refseq:XP_016885029.1|ensembl:ENSG00000101871(gene)|ensembl:ENST00000317552(transcript)|ensembl:ENST00000380779(transcript)|ensembl:ENST00000380780(transcript)|ensembl:ENST00000380785(transcript)|ensembl:ENST00000380787(transcript)|ensembl:ENST00000453318(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016740"(transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003649(B-box, C-terminal)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR027727|interpro:IPR036116|interpro:IPR040859|interpro:IPR043136|rcsb pdb:2DQ5|rcsb pdb:2FFW|rcsb pdb:2JUN|rcsb pdb:5IM8|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:NGlMGyFT7GEcrzVR/Iw4LitMBig9606	intact-crc:0B40A059CE33C5BE|rigid:uvhmnqSwV6I/cRD80tGGSaJdH5c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:P98170	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340813|imex:IM-11696-87	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	intact-crc:E34F05ACCDF13D31|rigid:JQajfDoZijWd1lx65/IgrpZduwI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q86Y13	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340828|imex:IM-11696-92	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:5BE91C73A98450B1|rigid:5Rhq0N3DDq0S4EQvjeCa6AS083U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99942	uniprotkb:Q9Y2X8	intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340822|imex:IM-11696-90	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:11308CC0432A973B|rigid:rKkdKKjuQDlTtSxs01k6FuZN9W8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBS8	uniprotkb:Q9Y2X8	intact:EBI-2130308|uniprotkb:B7ZLV2|uniprotkb:A0AV26|uniprotkb:A6NMR2|uniprotkb:B3KN72|uniprotkb:O94793|uniprotkb:Q6IBV0|uniprotkb:A8MTW5|uniprotkb:D3DQE4|ensembl:ENSP00000324956|ensembl:ENSP00000348462|ensembl:ENSP00000378027|ensembl:ENSP00000378028	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:rnf14_human(display_long)|uniprotkb:RNF14(gene name)|psi-mi:RNF14(display_short)|uniprotkb:ARA54(gene name synonym)|uniprotkb:RING finger protein 14(gene name synonym)|uniprotkb:Androgen receptor-associated protein 54(gene name synonym)|uniprotkb:Triad2 protein(gene name synonym)|uniprotkb:HFB30(gene name synonym)|uniprotkb:HRIHFB2038(orf name)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340825|imex:IM-11696-91	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011536016.1|refseq:NP_001188294.1|refseq:NP_004281.1|refseq:NP_899645.1|refseq:NP_899646.1|refseq:NP_899647.1|refseq:NP_899648.1|refseq:XP_016865559.1|refseq:XP_016865560.1|refseq:XP_016865561.1|refseq:XP_005268593.1|refseq:XP_005268594.1|refseq:XP_005268596.1|refseq:XP_005268597.1|refseq:XP_005268598.1|ensembl:ENSG00000013561(gene)|ensembl:ENST00000347642(transcript)|ensembl:ENST00000356143(transcript)|ensembl:ENST00000394519(transcript)|ensembl:ENST00000394520(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017907|interpro:IPR031127|interpro:IPR031128|interpro:IPR044066|mint:Q9UBS8|reactome:R-HSA-983168	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:zCNZ6kHw7XNUvpVBRQSgZ7ffJ9U9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:D19CA6F3EB904E63|rigid:XPyXztDD9EE8nSNZNKBQnlmJy+Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q8N5U6	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-714023|uniprotkb:Q92550|uniprotkb:Q9NPP8|uniprotkb:Q9ULW4|ensembl:ENSP00000322242	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:rnf10_human(display_long)|uniprotkb:RNF10(gene name)|psi-mi:RNF10(display_short)|uniprotkb:KIAA0262(gene name synonym)|uniprotkb:RIE2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340831|imex:IM-11696-93	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_055683.3|refseq:NP_001317403.1|ensembl:ENSG00000022840(gene)|ensembl:ENST00000325954(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039739|mint:Q8N5U6	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:Bca0Ae456x1eCsdlduoCbn7coUQ9606	intact-crc:B288F22CF0EA8AD9|rigid:vkXwDeSCXoXsDsP8Y25n/Gtvg2g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O94941	uniprotkb:Q9Y2X8	intact:EBI-751901|uniprotkb:Q6IAR5|uniprotkb:Q86X87|uniprotkb:Q9H4J2|ensembl:ENSP00000217173	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:rnf37_human(display_long)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 5(gene name synonym)|uniprotkb:U-box domain-containing protein 5(gene name synonym)|uniprotkb:UBOX5(gene name)|psi-mi:UBOX5(display_short)|uniprotkb:KIAA0860(gene name synonym)|uniprotkb:RNF37(gene name synonym)|uniprotkb:UBCE7IP5(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF37(gene name synonym)|uniprotkb:UIP5(gene name synonym)|uniprotkb:UbcM4-interacting protein 5(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340834|imex:IM-11696-94	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055763.1|refseq:NP_955447.1|ensembl:ENSG00000185019(gene)|ensembl:ENST00000217173(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039847|interpro:IPR039925|reactome:R-HSA-983168	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:bHUiSJ345KLIwL+xD2qH/CJVqL09606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:C5A0D726367A2118|rigid:1dcsPbm0EQETkxCWO/csazTe99A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q6ZNA4	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-2129175|uniprotkb:Q6ZMU2|uniprotkb:Q7L428|uniprotkb:Q7Z346|uniprotkb:Q8N1P9|uniprotkb:Q8WUA3|uniprotkb:Q9NSR1|uniprotkb:Q6P9A4|uniprotkb:C9JUS4|uniprotkb:H0YN55|ensembl:ENSP00000452732|intact:EBI-28970158	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:rn111_human(display_long)|uniprotkb:RNF111(gene name)|psi-mi:RNF111(display_short)|uniprotkb:RING finger protein 111(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Arkadia(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340843|imex:IM-11696-96	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_060080.6|ensembl:ENST00000348370|ensembl:ENSP00000288199|ensembl:ENSP00000452732|ensembl:ENST00000559209|ensembl:ENSP00000453872|ensembl:ENST00000561186|ensembl:ENSP00000453015|refseq:NP_001317260.1|refseq:XP_016877827.1|refseq:XP_006720642.1|refseq:NP_001257459.1|refseq:NP_001257457.1|refseq:NP_001257458.1|ensembl:ENSG00000157450(gene)|ensembl:ENST00000557998(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR029306|rcsb pdb:2KIZ|rcsb pdb:5LG0|rcsb pdb:5LG7|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-5696395|reactome:R-HSA-983168|go:"GO:0032184"(SUMO polymer binding)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:6SY5oMr5u4mnVi+zdRboVljMGa09606	intact-crc:AE4C15B57CF992A6|rigid:muwdFmGVxCb1V8C/HBtHMzYNJwM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q9Y3C5	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-396669|intact:EBI-2129167|uniprotkb:A8KAI2|uniprotkb:Q5T7R8|ensembl:ENSP00000242719	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:rnf11_human(display_long)|uniprotkb:CGI-123(orf name)|uniprotkb:RNF11(gene name)|psi-mi:RNF11(display_short)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340837|imex:IM-11696-401	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_055187.1|ensembl:ENSP00000242719|ensembl:ENSG00000123091(gene)|ensembl:ENST00000242719(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042981|mint:Q9Y3C5	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:Uj0YAf/t+AdYbMd6fgQ8hVKoP0w9606	intact-crc:1D9D149780A86FD5|rigid:QrgTf0I4BrJ0K3ndpd5vlXfK3SY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WVD3	uniprotkb:Q9Y2X8	intact:EBI-749039|uniprotkb:Q9H8K2|uniprotkb:Q9UF87|uniprotkb:Q9UKI6|uniprotkb:B2RE17|ensembl:ENSP00000261593	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:rn138_human(display_long)|uniprotkb:RING finger protein 138(gene name synonym)|uniprotkb:Nemo-like kinase-associated RING finger protein(gene name synonym)|uniprotkb:RNF138(gene name)|psi-mi:RNF138(display_short)|uniprotkb:NARF(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF138(gene name synonym)|uniprotkb:HSD-4(orf name)|uniprotkb:HSD4(orf name)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340840|imex:IM-11696-95	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057355.2|refseq:NP_937761.1|refseq:NP_001178253.2|refseq:XP_005258343.1|ensembl:ENSG00000134758(gene)|ensembl:ENST00000261593(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034734|reactome:R-HSA-983168	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:HhGscRenFoqXTiZxHR62E4wcIo09606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:B4BFC1FB1B038BCC|rigid:OJMpZXlTxiGt7voWZsJ0ov2BgYI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCM9	uniprotkb:Q9Y2X8	intact:EBI-739510|uniprotkb:Q5STG4|uniprotkb:Q76BL3|uniprotkb:Q8IYT9|uniprotkb:Q96IB6|ensembl:ENSP00000365844|ensembl:ENSP00000373096|ensembl:ENSP00000379796|ensembl:ENSP00000391917|ensembl:ENSP00000397043|ensembl:ENSP00000398355|ensembl:ENSP00000409902|ensembl:ENSP00000411949|ensembl:ENSP00000447835|ensembl:ENSP00000448462|ensembl:ENSP00000448572|ensembl:ENSP00000449272|ensembl:ENSP00000449847|ensembl:ENSP00000450288|uniprotkb:Q5STG3	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:tri39_human(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340852|imex:IM-11696-99	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376656(transcript)|ensembl:ENST00000383602(transcript)|ensembl:ENST00000396547(transcript)|ensembl:ENST00000413715(transcript)|ensembl:ENST00000424575(transcript)|ensembl:ENST00000445206(transcript)|ensembl:ENST00000426469(transcript)|ensembl:ENST00000451715(transcript)|ensembl:ENST00000547030(transcript)|ensembl:ENST00000548002(transcript)|ensembl:ENST00000549841(transcript)|ensembl:ENST00000550282(transcript)|ensembl:ENST00000552337(transcript)|ensembl:ENST00000552520(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035033|interpro:IPR043136|mint:Q9HCM9|rcsb pdb:2DID|rcsb pdb:2DIF|rcsb pdb:2ECJ|reactome:R-HSA-983168|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_067076.2|refseq:NP_742013.1	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xMCXGcMTqCjzLQzC53o81S4gqZA9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:96F2A9C3D3BD4E35|rigid:Ub5VHN+vJtuKQnqsScFHB3qlY28	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q96EQ8	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340846|imex:IM-11696-97	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	intact-crc:CEFC4E11E9F5950E|rigid:QNyYIHn/n2zA7c/uQ3kuOGSCo6A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BV68	uniprotkb:Q9Y2X8	intact:EBI-357322|ensembl:ENSP00000292363|uniprotkb:Q9NWX1|intact:EBI-11064977	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:rn126_human(display_long)|uniprotkb:RNF126(gene name)|psi-mi:RNF126(display_short)|uniprotkb:RING finger protein 126(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340849|imex:IM-11696-98	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000070423(gene)|ensembl:ENST00000292363(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR039525|interpro:IPR039571|interpro:IPR039572|rcsb pdb:2N9O|rcsb pdb:2N9P|reactome:R-HSA-983168|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|refseq:NP_919442.1	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2019/01/23	rogid:4Z4AJGHJgoIUp9zhtfWcFBF1Fxw9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:CB46E394ADD74E76|rigid:5jyW+P/wljg6k9hVkR/yNbC2cJs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BH1	uniprotkb:Q9Y2X8	intact:EBI-2129220|uniprotkb:A8K0D6|uniprotkb:Q9H874|uniprotkb:Q53HQ5|ensembl:ENSP00000295704	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:rnf25_human(display_long)|uniprotkb:RNF25(gene name)|psi-mi:RNF25(display_short)|uniprotkb:RING finger protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF25(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340855|imex:IM-11696-100	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071898.2|dip:DIP-29063N|ensembl:ENSG00000163481(gene)|ensembl:ENST00000295704(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR039133|rcsb pdb:2DAY|rcsb pdb:2DMF|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|reactome:R-HSA-983168	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:YyCN7mH4eng9G05zRci49oJzKO09606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:3E7E01C0082EFA6F|rigid:zeQFdMVzGYyJM/eNEuxFkNajhCQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZR9	uniprotkb:Q9Y2X8	intact:EBI-2340370|uniprotkb:Q9C028|uniprotkb:A6NI31|intact:EBI-2796718|ensembl:ENSP00000496301	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:trim8_human(display_long)|uniprotkb:Tripartite motif-containing protein 8(gene name synonym)|uniprotkb:TRIM8(gene name)|psi-mi:TRIM8(display_short)|uniprotkb:GERP(gene name synonym)|uniprotkb:RNF27(gene name synonym)|uniprotkb:RING finger protein 27(gene name synonym)|uniprotkb:Glioblastoma-expressed RING finger protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM8(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340858|imex:IM-11696-101	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112174.2|ensembl:ENSG00000171206(gene)|ensembl:ENST00000643721(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0016740"(transferase activity)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902187"|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-877300	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:WFqavXVFV3/XbJSA2k06Pg9Eaag9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:1E3E00EF570C2385|rigid:H6LXZvH2i0Amcp61/+x0Wi9rnMc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q8ND25	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340861|imex:IM-11696-102	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	intact-crc:7E9259FCD1EA8A3C|rigid:mH4bJ7EzaYlJ45XsaG8i4IFaz/k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96GF1	uniprotkb:Q9Y2X8	intact:EBI-2340249|uniprotkb:A8K5C1|uniprotkb:A9X3T8|uniprotkb:Q8N900|ensembl:ENSP00000320508|ensembl:ENSP00000427755	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:rn185_human(display_long)|uniprotkb:RNF185(gene name)|psi-mi:RNF185(display_short)|uniprotkb:RING finger protein 185(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF185(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340864|imex:IM-11696-103	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001129297.1|refseq:NP_689480.2|ensembl:ENSG00000138942(gene)|ensembl:ENST00000326132(transcript)|ensembl:ENST00000518626(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ivzbt31KPTKL/Rc1Wzs3h80XJac9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:957FC6D8D0982101|rigid:yL0u1FKmcG3gr/bzoOgsmqc8qa0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TDB6	uniprotkb:Q9Y2X8	intact:EBI-2340392|uniprotkb:Q5MJP7|uniprotkb:Q53ZZ3|uniprotkb:B3KWH6|ensembl:ENSP00000296161	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:dtx3l_human(display_long)|uniprotkb:DTX3L(gene name)|psi-mi:DTX3L(display_short)|uniprotkb:BBAP(gene name synonym)|uniprotkb:B-lymphoma- and BAL-associated protein(gene name synonym)|uniprotkb:Rhysin-2(gene name synonym)|uniprotkb:Protein deltex-3-like(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3L(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340873|imex:IM-11696-106	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612144.1|ensembl:ENSG00000163840(gene)|ensembl:ENST00000296161(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0015031"(protein transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:2000646"(positive regulation of receptor catabolic process)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|interpro:IPR042843|rcsb pdb:3PG6|reactome:R-HSA-983168	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:d2ctDfd7pj1wRA3HxmyWJ5nL19Y9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:FCDF5B067B4BE76B|rigid:Lhci02TGVYQZmbQTgZgk0XkYXsY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q96A37	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-2130320|uniprotkb:B3KQ03|uniprotkb:Q96DM0|uniprotkb:D3DX75|uniprotkb:H3BTU8|ensembl:ENSP00000326095	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:rn166_human(display_long)|uniprotkb:RNF166(gene name)|psi-mi:RNF166(display_short)|uniprotkb:RING finger protein 166(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF166(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340867|imex:IM-11696-104	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_001165286.1|refseq:NP_001165287.1|refseq:NP_849163.1|refseq:XP_016878402.1|ensembl:ENSG00000158717(gene)|ensembl:ENST00000312838(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:QV195sbjVofHePvnO8nsleiWSkg9606	intact-crc:C0DFC474F69820F1|rigid:/OGzB2WbV7U5HvcV8T7M4jOvIaM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q96BQ3	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-2129899|uniprotkb:Q53TJ7|ensembl:ENSP00000272395	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:tri43_human(display_long)|uniprotkb:TRIM43(gene name)|psi-mi:TRIM43(display_short)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340870|imex:IM-11696-105	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_620155.1|ensembl:ENSG00000144015(gene)|ensembl:ENST00000272395(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0045087"(innate immune response)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR043136	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:pfo60amX0NFspl9zqQ/Cgek6yO09606	intact-crc:58A56DF2659821A5|rigid:7g+bAOWiDCAmS4Lyc+072A84joA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N9I9	uniprotkb:Q9Y2X8	intact:EBI-2340258|uniprotkb:Q8NDS8|uniprotkb:Q8NAU6|uniprotkb:Q53ZZ2|ensembl:ENSP00000338050|ensembl:ENSP00000447873|ensembl:ENSP00000449294	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:dtx3_human(display_long)|uniprotkb:DTX3(gene name)|psi-mi:DTX3(display_short)|uniprotkb:RNF154(gene name synonym)|uniprotkb:RING finger protein 154(gene name synonym)|uniprotkb:Protein deltex-3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340876|imex:IM-11696-107	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273174.1|refseq:NP_001273175.1|refseq:XP_011536324.1|refseq:NP_848597.1|refseq:XP_005268754.1|refseq:XP_005268755.1|refseq:XP_005268757.1|refseq:XP_005268760.1|ensembl:ENSG00000178498(gene)|ensembl:ENST00000337737(transcript)|ensembl:ENST00000548198(transcript)|ensembl:ENST00000548804(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Ma7JBhgMdFofCeWESbf8h1iLAHY9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:B3625CE2BCEA89EF|rigid:+4O62gRrUCSHLPbxlq5d/Xm4zU0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IZP6	uniprotkb:Q712K3	intact:EBI-2340677|uniprotkb:Q96QY9|uniprotkb:Q8WWF9|ensembl:ENSP00000267291	intact:EBI-2340879|uniprotkb:Q9NX64|uniprotkb:D3DRL5|ensembl:ENSP00000263228	psi-mi:r113b_human(display_long)|uniprotkb:RNF113B(gene name)|psi-mi:RNF113B(display_short)|uniprotkb:RNF161(gene name synonym)|uniprotkb:ZNF183L1(gene name synonym)|uniprotkb:Zinc finger protein 183-like 1(gene name synonym)	psi-mi:ub2r2_human(display_long)|uniprotkb:UBE2R2(gene name)|psi-mi:UBE2R2(display_short)|uniprotkb:CDC34B(gene name synonym)|uniprotkb:UBC3B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase R2(gene name synonym)|uniprotkb:Ubiquitin carrier protein R2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-CDC34B(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme R2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340884|imex:IM-11696-108	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_849192.1|ensembl:ENSG00000139797(gene)|ensembl:ENST00000267291(transcript)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036855|interpro:IPR039971|rcsb pdb:2CSY	refseq:NP_060281.2|ensembl:ENSG00000107341(gene)|ensembl:ENST00000263228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:6NYO|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:v4QnmiYlYp4zInfMBKQQxTUnrd89606	rogid:fFTiply+7nUD6veFiQW5xcNmRrE9606	intact-crc:1D375E056C581847|rigid:PzGPLC4uydHWjuXSmY3ees7pRbc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76064	uniprotkb:Q96B02	intact:EBI-373337|uniprotkb:Q53H16|uniprotkb:Q5NKW5|uniprotkb:A6NN24|uniprotkb:A8MYC0|uniprotkb:B4DPG0|ensembl:ENSP00000362578	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:rnf8_human(display_long)|uniprotkb:RNF8(gene name)|psi-mi:RNF8(display_short)|uniprotkb:KIAA0646(gene name synonym)|uniprotkb:RING finger protein 8(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF8(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340897|imex:IM-11696-111	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003949.1|refseq:NP_898901.1|ensembl:ENST00000373479(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007286"(spermatid development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|mint:O76064|rcsb pdb:2CSW|rcsb pdb:2PIE|rcsb pdb:4AYC|rcsb pdb:4ORH|rcsb pdb:4WHV|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|interpro:IPR017907|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043486"(histone exchange)|go:"GO:0045190"(isotype switching)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051301"(cell division)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070535"(histone H2A K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017335(E3 ubiquitin ligase, RNF8)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|ensembl:ENSG00000112130(gene)|dip:DIP-31265N	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:nsYlZhRT5wsltOEjHh1l815IphQ9606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:FBDC28E3C6D12FF5|rigid:STl1CwOTLe5fW2g77Kqj9+Cy0Ks	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKV5	uniprotkb:Q96B02	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340891|imex:IM-11696-109	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:AD1C2BDEE31631B7|rigid:4sgW/3idZ/nSBg1JX68zoR0zB7M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:O15344	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-2340316|uniprotkb:Q9BZX5|uniprotkb:O75361|uniprotkb:B2RCG2|ensembl:ENSP00000312678|ensembl:ENSP00000370156|ensembl:ENSP00000370157|ensembl:ENSP00000370162|ensembl:ENSP00000370164|ensembl:ENSP00000414521	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:tri18_human(display_long)|uniprotkb:MID1(gene name)|psi-mi:MID1(display_short)|uniprotkb:FXY(gene name synonym)|uniprotkb:RNF59(gene name synonym)|uniprotkb:TRIM18(gene name synonym)|uniprotkb:XPRF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 18(gene name synonym)|uniprotkb:Putative transcription factor XPRF(gene name synonym)|uniprotkb:Midin(gene name synonym)|uniprotkb:RING finger protein 59(gene name synonym)|uniprotkb:RING finger protein Midline-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Midline-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340894|imex:IM-11696-110	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_000372.1|refseq:NP_001092094.1|refseq:NP_001180206.1|refseq:NP_001180207.1|refseq:NP_001180208.1|refseq:NP_001180209.1|refseq:NP_001180210.1|refseq:NP_150632.1|refseq:NP_001334662.1|refseq:XP_016885025.1|refseq:XP_016885029.1|ensembl:ENSG00000101871(gene)|ensembl:ENST00000317552(transcript)|ensembl:ENST00000380779(transcript)|ensembl:ENST00000380780(transcript)|ensembl:ENST00000380785(transcript)|ensembl:ENST00000380787(transcript)|ensembl:ENST00000453318(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016740"(transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003649(B-box, C-terminal)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR027727|interpro:IPR036116|interpro:IPR040859|interpro:IPR043136|rcsb pdb:2DQ5|rcsb pdb:2FFW|rcsb pdb:2JUN|rcsb pdb:5IM8|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:NGlMGyFT7GEcrzVR/Iw4LitMBig9606	intact-crc:157D77E8E30B09F5|rigid:9JTwGtJWHDAGOHG0MVzaNorSDJ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q86Y13	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340903|imex:IM-11696-113	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:45D4CBC284BC9CFA|rigid:HYtha5mNnj5jEqIU3YBVka/4hgA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBS8	uniprotkb:Q96B02	intact:EBI-2130308|uniprotkb:B7ZLV2|uniprotkb:A0AV26|uniprotkb:A6NMR2|uniprotkb:B3KN72|uniprotkb:O94793|uniprotkb:Q6IBV0|uniprotkb:A8MTW5|uniprotkb:D3DQE4|ensembl:ENSP00000324956|ensembl:ENSP00000348462|ensembl:ENSP00000378027|ensembl:ENSP00000378028	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:rnf14_human(display_long)|uniprotkb:RNF14(gene name)|psi-mi:RNF14(display_short)|uniprotkb:ARA54(gene name synonym)|uniprotkb:RING finger protein 14(gene name synonym)|uniprotkb:Androgen receptor-associated protein 54(gene name synonym)|uniprotkb:Triad2 protein(gene name synonym)|uniprotkb:HFB30(gene name synonym)|uniprotkb:HRIHFB2038(orf name)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340900|imex:IM-11696-112	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011536016.1|refseq:NP_001188294.1|refseq:NP_004281.1|refseq:NP_899645.1|refseq:NP_899646.1|refseq:NP_899647.1|refseq:NP_899648.1|refseq:XP_016865559.1|refseq:XP_016865560.1|refseq:XP_016865561.1|refseq:XP_005268593.1|refseq:XP_005268594.1|refseq:XP_005268596.1|refseq:XP_005268597.1|refseq:XP_005268598.1|ensembl:ENSG00000013561(gene)|ensembl:ENST00000347642(transcript)|ensembl:ENST00000356143(transcript)|ensembl:ENST00000394519(transcript)|ensembl:ENST00000394520(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017907|interpro:IPR031127|interpro:IPR031128|interpro:IPR044066|mint:Q9UBS8|reactome:R-HSA-983168	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:zCNZ6kHw7XNUvpVBRQSgZ7ffJ9U9606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:AF6942B8207EEAE6|rigid:0s+5yn8+hl9pu2Py/j6qtliHZkA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q9Y577	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-743894|uniprotkb:B4DVJ2|uniprotkb:Q5VST8|ensembl:ENSP00000295033|ensembl:ENSP00000355658|ensembl:ENSP00000355659|ensembl:ENSP00000493891|ensembl:ENSP00000495842|ensembl:ENSP00000496098	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:tri17_human(display_long)|uniprotkb:Testis RING finger protein(gene name synonym)|uniprotkb:RING finger protein 16(gene name synonym)|uniprotkb:TRIM17(gene name)|psi-mi:TRIM17(display_short)|uniprotkb:RBCC(gene name synonym)|uniprotkb:RNF16(gene name synonym)|uniprotkb:TERF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 17(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM17(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340912|imex:IM-11696-117	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	ensembl:ENSG00000162931(gene)|ensembl:ENSG00000285344(gene)|refseq:NP_001020111.1|refseq:NP_001128327.1|refseq:NP_057186.1|refseq:XP_011542511.1|refseq:XP_011542512.1|refseq:XP_006711842.1|ensembl:ENST00000295033(transcript)|ensembl:ENST00000366697(transcript)|ensembl:ENST00000366698(transcript)|ensembl:ENST00000645562(transcript)|ensembl:ENST00000645958(transcript)|ensembl:ENST00000647385(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045087"(innate immune response)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032918|interpro:IPR035687|interpro:IPR043136|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:pXiCDkeNMtq9icQduH4MSCM6vSQ9606	intact-crc:88FFF34D974253C4|rigid:Dch01Qf1Kx4ghKMYNPT0K7s3sjo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O94941	uniprotkb:Q96B02	intact:EBI-751901|uniprotkb:Q6IAR5|uniprotkb:Q86X87|uniprotkb:Q9H4J2|ensembl:ENSP00000217173	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:rnf37_human(display_long)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 5(gene name synonym)|uniprotkb:U-box domain-containing protein 5(gene name synonym)|uniprotkb:UBOX5(gene name)|psi-mi:UBOX5(display_short)|uniprotkb:KIAA0860(gene name synonym)|uniprotkb:RNF37(gene name synonym)|uniprotkb:UBCE7IP5(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF37(gene name synonym)|uniprotkb:UIP5(gene name synonym)|uniprotkb:UbcM4-interacting protein 5(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340906|imex:IM-11696-114	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055763.1|refseq:NP_955447.1|ensembl:ENSG00000185019(gene)|ensembl:ENST00000217173(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039847|interpro:IPR039925|reactome:R-HSA-983168	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:bHUiSJ345KLIwL+xD2qH/CJVqL09606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:DB9D00971B42ED53|rigid:VZrCn6lGhO4QXiFVJ3pRCPKJvfM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UPQ4	uniprotkb:Q96B02	intact:EBI-2130401|uniprotkb:Q86XQ0|uniprotkb:Q8WVA4|ensembl:ENSP00000301924	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:tri35_human(display_long)|uniprotkb:TRIM35(gene name)|psi-mi:TRIM35(display_short)|uniprotkb:HLS5(gene name synonym)|uniprotkb:KIAA1098(gene name synonym)|uniprotkb:Hemopoietic lineage switch protein 5(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340909|imex:IM-11696-115	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741983.2|ensembl:ENSG00000104228(gene)|ensembl:ENST00000305364(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR043136|reactome:R-HSA-877300	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:VlC2XEURqN7nMIfIns2E0QVsL7k9606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:2F63D14448AD4EA5|rigid:w7EaNUK75bGhZPjWJ6MrnICzfY4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q96A37	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-2130320|uniprotkb:B3KQ03|uniprotkb:Q96DM0|uniprotkb:D3DX75|uniprotkb:H3BTU8|ensembl:ENSP00000326095	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:rn166_human(display_long)|uniprotkb:RNF166(gene name)|psi-mi:RNF166(display_short)|uniprotkb:RING finger protein 166(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF166(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340921|imex:IM-11696-120	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_001165286.1|refseq:NP_001165287.1|refseq:NP_849163.1|refseq:XP_016878402.1|ensembl:ENSG00000158717(gene)|ensembl:ENST00000312838(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:QV195sbjVofHePvnO8nsleiWSkg9606	intact-crc:DEE213C5DBA0ECBA|rigid:0STY+zsXF7pjmEDRYa1aVxzU5LE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZR9	uniprotkb:Q96B02	intact:EBI-2340370|uniprotkb:Q9C028|uniprotkb:A6NI31|intact:EBI-2796718|ensembl:ENSP00000496301	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:trim8_human(display_long)|uniprotkb:Tripartite motif-containing protein 8(gene name synonym)|uniprotkb:TRIM8(gene name)|psi-mi:TRIM8(display_short)|uniprotkb:GERP(gene name synonym)|uniprotkb:RNF27(gene name synonym)|uniprotkb:RING finger protein 27(gene name synonym)|uniprotkb:Glioblastoma-expressed RING finger protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM8(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340915|imex:IM-11696-118	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112174.2|ensembl:ENSG00000171206(gene)|ensembl:ENST00000643721(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0016740"(transferase activity)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902187"|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-877300	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:WFqavXVFV3/XbJSA2k06Pg9Eaag9606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:A45E005D0E5C61FF|rigid:szpH5E8wDGmUcbo2VVyZd0g9rbk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q8ND25	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340918|imex:IM-11696-119	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	intact-crc:60AF8E4DFCD24677|rigid:73758sTN5/B//yupdNaNq8vs7IY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q8TDB6	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-2340392|uniprotkb:Q5MJP7|uniprotkb:Q53ZZ3|uniprotkb:B3KWH6|ensembl:ENSP00000296161	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:dtx3l_human(display_long)|uniprotkb:DTX3L(gene name)|psi-mi:DTX3L(display_short)|uniprotkb:BBAP(gene name synonym)|uniprotkb:B-lymphoma- and BAL-associated protein(gene name synonym)|uniprotkb:Rhysin-2(gene name synonym)|uniprotkb:Protein deltex-3-like(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3L(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340924|imex:IM-11696-121	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_612144.1|ensembl:ENSG00000163840(gene)|ensembl:ENST00000296161(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0015031"(protein transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:2000646"(positive regulation of receptor catabolic process)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|interpro:IPR042843|rcsb pdb:3PG6|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:d2ctDfd7pj1wRA3HxmyWJ5nL19Y9606	intact-crc:E2E28CB756732B20|rigid:qEdefJijlQ8qafOJMQSfaTcawBg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P78317	uniprotkb:Q8IX04	intact:EBI-2340927|uniprotkb:Q49AR8|uniprotkb:B2R6D6|uniprotkb:D6RF58|intact:EBI-28970119|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503	intact:EBI-2339926|uniprotkb:Q96FF5|uniprotkb:Q6P2F0|uniprotkb:Q9NUX7|uniprotkb:B2RB69|uniprotkb:F5H6L6|uniprotkb:B4DL43|uniprotkb:H7BYD6|ensembl:ENSP00000379500	psi-mi:rnf4_human(display_long)|uniprotkb:SNURF(gene name synonym)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:RNF4(gene name)|psi-mi:RNF4(display_short)|uniprotkb:RES4-26(orf name)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:uevld_human(display_long)|uniprotkb:UEVLD(gene name)|psi-mi:UEVLD(display_short)|uniprotkb:UEV3(gene name synonym)|uniprotkb:EV and lactate/malate dehydrogenase domain-containing protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340932|imex:IM-11696-122	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171938.1|refseq:NP_001171939.1|refseq:NP_002929.1|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503|ensembl:ENST00000511859|ensembl:ENSP00000426615|ensembl:ENST00000541204|ensembl:ENSP00000446369|ensembl:ENSG00000063978(gene)|ensembl:ENST00000314289(transcript)|ensembl:ENST00000506706(transcript)|ensembl:ENST00000511600(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|go:"GO:1990752"(microtubule end)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|mint:P78317|rcsb pdb:2EA6|rcsb pdb:2XEU|rcsb pdb:4PPE|reactome:R-HSA-5693607|reactome:R-HSA-983168	refseq:NP_001035787.1|refseq:NP_060784.3|refseq:NP_001284700.1|refseq:NP_001248312.1|refseq:NP_001248314.1|refseq:NP_001248311.1|refseq:NP_001248315.1|ensembl:ENSG00000151116(gene)|ensembl:ENST00000396197(transcript)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0015031"(protein transport)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR022383|interpro:IPR036291|rcsb pdb:2I6T|rcsb pdb:3DL2	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Yhu2iAaNQYcfGdYohDPBdhMFEpc9606	rogid:ZoLQ2ktG7JpK/ocZ+iC65EG5vrc9606	intact-crc:786D45F4BA6DC85E|rigid:YnwI0L5se97ojm4dwT0PNptIvBI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0C9	uniprotkb:Q8N5U6	intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687	intact:EBI-714023|uniprotkb:Q92550|uniprotkb:Q9NPP8|uniprotkb:Q9ULW4|ensembl:ENSP00000322242	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	psi-mi:rnf10_human(display_long)|uniprotkb:RNF10(gene name)|psi-mi:RNF10(display_short)|uniprotkb:KIAA0262(gene name synonym)|uniprotkb:RIE2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340941|imex:IM-11696-125	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168	refseq:NP_055683.3|refseq:NP_001317403.1|ensembl:ENSG00000022840(gene)|ensembl:ENST00000325954(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039739|mint:Q8N5U6	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	rogid:Bca0Ae456x1eCsdlduoCbn7coUQ9606	intact-crc:E1F1F7F7F87B5ACF|rigid:c4NM2cuPWSdlqp211rPRVX8RDU8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IX04	uniprotkb:Q9Y508	intact:EBI-2339926|uniprotkb:Q96FF5|uniprotkb:Q6P2F0|uniprotkb:Q9NUX7|uniprotkb:B2RB69|uniprotkb:F5H6L6|uniprotkb:B4DL43|uniprotkb:H7BYD6|ensembl:ENSP00000379500	intact:EBI-723587|uniprotkb:Q6N0B0|uniprotkb:B2RDQ9|uniprotkb:B4DWY5|uniprotkb:E1P627|ensembl:ENSP00000244061	psi-mi:uevld_human(display_long)|uniprotkb:UEVLD(gene name)|psi-mi:UEVLD(display_short)|uniprotkb:UEV3(gene name synonym)|uniprotkb:EV and lactate/malate dehydrogenase domain-containing protein(gene name synonym)	psi-mi:rn114_human(display_long)|uniprotkb:Zinc finger protein 313(gene name synonym)|uniprotkb:RNF114(gene name)|psi-mi:RNF114(display_short)|uniprotkb:ZNF313(gene name synonym)|uniprotkb:ZNF228(gene name synonym)|uniprotkb:Zinc finger protein 228(gene name synonym)|uniprotkb:RING finger protein 114(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF114(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340935|imex:IM-11696-123	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035787.1|refseq:NP_060784.3|refseq:NP_001284700.1|refseq:NP_001248312.1|refseq:NP_001248314.1|refseq:NP_001248311.1|refseq:NP_001248315.1|ensembl:ENSG00000151116(gene)|ensembl:ENST00000396197(transcript)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0015031"(protein transport)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR022383|interpro:IPR036291|rcsb pdb:2I6T|rcsb pdb:3DL2	refseq:NP_061153.1|ensembl:ENSG00000124226(gene)|ensembl:ENST00000244061(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR034734|interpro:IPR042716|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ZoLQ2ktG7JpK/ocZ+iC65EG5vrc9606	rogid:R1fX8xaGuIhy/M6cLzPeyfJBf649606	intact-crc:077248CF0811672E|rigid:4X4t9wXw4pWhCL9+E1dBkh9Pm9w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBF6	uniprotkb:Q7Z7E8	intact:EBI-398632|uniprotkb:Q9BXN8|uniprotkb:Q9Y5M7|uniprotkb:A8MTB5|uniprotkb:A8K1H9|uniprotkb:D3DNF7|uniprotkb:D3DNF8|uniprotkb:C9JYL3|ensembl:ENSP00000273480	intact:EBI-1783287|uniprotkb:Q3B841|uniprotkb:Q5I0X2|uniprotkb:Q6IS04|uniprotkb:Q6P7P2|uniprotkb:Q96MV4|uniprotkb:Q9BVX5|uniprotkb:Q9UGL6|uniprotkb:B4DF92|uniprotkb:Q29SN7|ensembl:ENSP00000292211	psi-mi:rbx2_human(display_long)|uniprotkb:RNF7(gene name)|psi-mi:RNF7(display_short)|uniprotkb:RBX2(gene name synonym)|uniprotkb:ROC2(gene name synonym)|uniprotkb:SAG(gene name synonym)|uniprotkb:RING finger protein 7(gene name synonym)|uniprotkb:Regulator of cullins 2(gene name synonym)|uniprotkb:CKII beta-binding protein 1(gene name synonym)|uniprotkb:Sensitive to apoptosis gene protein(gene name synonym)	psi-mi:ub2q1_human(display_long)|uniprotkb:UBE2Q1(gene name)|psi-mi:UBE2Q1(display_short)|uniprotkb:NICE5(gene name synonym)|uniprotkb:UBE2Q(gene name synonym)|uniprotkb:PRO3094(orf name)|uniprotkb:Ubiquitin-protein ligase Q1(gene name synonym)|uniprotkb:Ubiquitin carrier protein Q1(gene name synonym)|uniprotkb:Protein NICE-5(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme Q1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340938|imex:IM-11696-124	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055060.1|refseq:NP_899060.1|refseq:NP_001188299.1|ensembl:ENSG00000114125(gene)|ensembl:ENST00000273480(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045116"(protein neddylation)|go:"GO:0051775"(response to redox state)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|rcsb pdb:2ECL|reactome:R-HSA-8951664|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_060052.3|ensembl:ENSG00000160714(gene)|ensembl:ENST00000292211(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001967"(suckling behavior)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007566"(embryo implantation)|go:"GO:0007617"(mating behavior)|go:"GO:0009566"(fertilization)|go:"GO:0030175"(filopodium)|go:"GO:0061458"(reproductive system development)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070459"(prolactin secretion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2QGX|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:FNop0ozErv05khKc5si7nNH/Hww9606	rogid:Jxlo/WdqxS0sfr76bmPqj9AnYE09606	intact-crc:FD77C3264934D90E|rigid:zkg3uZ0DwChg2GyzgVc/R8MNCGA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H8T0	uniprotkb:Q86Y13	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340944|imex:IM-11696-126	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:1C1C6785BFCD302A|rigid:qrkGyWVKVqJ22S54jtVDEjPZNCk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H832	uniprotkb:Q8N448	intact:EBI-720977|uniprotkb:A6N8M6|uniprotkb:Q7L354|uniprotkb:Q8TCM4|uniprotkb:Q9H893|uniprotkb:A6NC60|ensembl:ENSP00000354201	intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224	psi-mi:ube2z_human(display_long)|uniprotkb:Ubiquitin-protein ligase Z(gene name synonym)|uniprotkb:Ubiquitin carrier protein Z(gene name synonym)|uniprotkb:Uba6-specific E2 conjugating enzyme 1(gene name synonym)|uniprotkb:UBE2Z(gene name)|psi-mi:UBE2Z(display_short)|uniprotkb:HOYS7(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme Z(gene name synonym)	psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340954|imex:IM-11696-127	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075567.2|ensembl:ENSG00000159202(gene)|ensembl:ENST00000360943(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:5A4P|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ha+cN8Y8XYZFrRnAQC9BRiMaUL89606	rogid:cIS5t4XkbnIgelDlUc692nI285g9606	intact-crc:F5E53560648B1D7F|rigid:2uRJun8nYUcpCkYR+Nsgaz2hQQ8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VVX9	uniprotkb:Q9H270	intact:EBI-2130181|uniprotkb:Q8N1D4|intact:EBI-28974117|ensembl:ENSP00000481174	intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6|ensembl:ENSP00000479680	psi-mi:ube2u_human(display_long)|uniprotkb:UBE2U(gene name)|psi-mi:UBE2U(display_short)|uniprotkb:Ubiquitin-protein ligase U(gene name synonym)|uniprotkb:Ubiquitin carrier protein U(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme U(gene name synonym)	psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340963|imex:IM-11696-130	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000371076|ensembl:ENSP00000360116|ensembl:ENSP00000481174|refseq:NP_689702.1|ensembl:ENSG00000177414(gene)|ensembl:ENST00000611228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033503"(HULC complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YRV|reactome:R-HSA-983168	refseq:NP_068375.3|refseq:NP_001277114.1|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|ensembl:ENSG00000160695(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENST00000620429(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0007033"(vacuole organization)|go:"GO:0048284"(organelle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:onw4DUslrZLhQZp8FtqY6s6Q/u09606	rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606	intact-crc:2D879A22F738862C|rigid:3Axl7NheTm6R8RkboF/BGVtDS38	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VVX9	uniprotkb:P36406	intact:EBI-2130181|uniprotkb:Q8N1D4|intact:EBI-28974117|ensembl:ENSP00000481174	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	psi-mi:ube2u_human(display_long)|uniprotkb:UBE2U(gene name)|psi-mi:UBE2U(display_short)|uniprotkb:Ubiquitin-protein ligase U(gene name synonym)|uniprotkb:Ubiquitin carrier protein U(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme U(gene name synonym)	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340957|imex:IM-11696-128	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000371076|ensembl:ENSP00000360116|ensembl:ENSP00000481174|refseq:NP_689702.1|ensembl:ENSG00000177414(gene)|ensembl:ENST00000611228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033503"(HULC complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YRV|reactome:R-HSA-983168	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:onw4DUslrZLhQZp8FtqY6s6Q/u09606	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	intact-crc:918F607129A5D1F3|rigid:AL3ZZ6PtspFqJPlPuFwlC7zml6o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BYM8	uniprotkb:Q5VVX9	intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632	intact:EBI-2130181|uniprotkb:Q8N1D4|intact:EBI-28974117|ensembl:ENSP00000481174	psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym)	psi-mi:ube2u_human(display_long)|uniprotkb:UBE2U(gene name)|psi-mi:UBE2U(display_short)|uniprotkb:Ubiquitin-protein ligase U(gene name synonym)|uniprotkb:Ubiquitin carrier protein U(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme U(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340960|imex:IM-11696-129	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006453.1|refseq:NP_112506.2|ensembl:ENSG00000125826(gene)|ensembl:ENST00000356286(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR026261|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|dip:DIP-47737N	ensembl:ENST00000371076|ensembl:ENSP00000360116|ensembl:ENSP00000481174|refseq:NP_689702.1|ensembl:ENSG00000177414(gene)|ensembl:ENST00000611228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033503"(HULC complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YRV|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606	rogid:onw4DUslrZLhQZp8FtqY6s6Q/u09606	intact-crc:92504DA4D997ADA2|rigid:TgslET9AMSPoB2XZ0XqQC2+aAkM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:O15344	intact:EBI-2340216	intact:EBI-2340316|uniprotkb:Q9BZX5|uniprotkb:O75361|uniprotkb:B2RCG2|ensembl:ENSP00000312678|ensembl:ENSP00000370156|ensembl:ENSP00000370157|ensembl:ENSP00000370162|ensembl:ENSP00000370164|ensembl:ENSP00000414521	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:tri18_human(display_long)|uniprotkb:MID1(gene name)|psi-mi:MID1(display_short)|uniprotkb:FXY(gene name synonym)|uniprotkb:RNF59(gene name synonym)|uniprotkb:TRIM18(gene name synonym)|uniprotkb:XPRF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 18(gene name synonym)|uniprotkb:Putative transcription factor XPRF(gene name synonym)|uniprotkb:Midin(gene name synonym)|uniprotkb:RING finger protein 59(gene name synonym)|uniprotkb:RING finger protein Midline-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Midline-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340972|imex:IM-11696-133	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:NP_000372.1|refseq:NP_001092094.1|refseq:NP_001180206.1|refseq:NP_001180207.1|refseq:NP_001180208.1|refseq:NP_001180209.1|refseq:NP_001180210.1|refseq:NP_150632.1|refseq:NP_001334662.1|refseq:XP_016885025.1|refseq:XP_016885029.1|ensembl:ENSG00000101871(gene)|ensembl:ENST00000317552(transcript)|ensembl:ENST00000380779(transcript)|ensembl:ENST00000380780(transcript)|ensembl:ENST00000380785(transcript)|ensembl:ENST00000380787(transcript)|ensembl:ENST00000453318(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016740"(transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003649(B-box, C-terminal)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR027727|interpro:IPR036116|interpro:IPR040859|interpro:IPR043136|rcsb pdb:2DQ5|rcsb pdb:2FFW|rcsb pdb:2JUN|rcsb pdb:5IM8|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:NGlMGyFT7GEcrzVR/Iw4LitMBig9606	intact-crc:EB7C3F7F6B63995A|rigid:gOPqNVs1dIcE7Dnqfci6pSs2XIU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86UV6	uniprotkb:Q5VVX9	intact:EBI-2340301|uniprotkb:B7WP46|ensembl:ENSP00000285805	intact:EBI-2130181|uniprotkb:Q8N1D4|intact:EBI-28974117|ensembl:ENSP00000481174	psi-mi:tri74_human(display_long)|uniprotkb:TRIM74(gene name)|psi-mi:TRIM74(display_short)|uniprotkb:TRIM50C(gene name synonym)|uniprotkb:Tripartite motif-containing protein 50C(gene name synonym)	psi-mi:ube2u_human(display_long)|uniprotkb:UBE2U(gene name)|psi-mi:UBE2U(display_short)|uniprotkb:Ubiquitin-protein ligase U(gene name synonym)|uniprotkb:Ubiquitin carrier protein U(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme U(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340966|imex:IM-11696-131	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011514489.1|refseq:XP_011514491.1|refseq:NP_942150.1|refseq:NP_001304744.1|ensembl:ENSG00000155428(gene)|ensembl:ENST00000285805(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370	ensembl:ENST00000371076|ensembl:ENSP00000360116|ensembl:ENSP00000481174|refseq:NP_689702.1|ensembl:ENSG00000177414(gene)|ensembl:ENST00000611228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033503"(HULC complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YRV|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:WsQRuhH8SQPPbtieNAA8PyDpwpE9606	rogid:onw4DUslrZLhQZp8FtqY6s6Q/u09606	intact-crc:949F4026ED450636|rigid:SkJEM2E90CImnxN60sa3SJt5fCY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IWF7	uniprotkb:Q9Y508	intact:EBI-2340154	intact:EBI-723587|uniprotkb:Q6N0B0|uniprotkb:B2RDQ9|uniprotkb:B4DWY5|uniprotkb:E1P627|ensembl:ENSP00000244061	psi-mi:u2d2l_human(display_long)|uniprotkb:UBE2DNL(gene name)|psi-mi:UBE2DNL(display_short)|uniprotkb:UBE2D2L(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2-like(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2-like(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2D N-terminal-like(gene name synonym)	psi-mi:rn114_human(display_long)|uniprotkb:Zinc finger protein 313(gene name synonym)|uniprotkb:RNF114(gene name)|psi-mi:RNF114(display_short)|uniprotkb:ZNF313(gene name synonym)|uniprotkb:ZNF228(gene name synonym)|uniprotkb:Zinc finger protein 228(gene name synonym)|uniprotkb:RING finger protein 114(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF114(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340969|imex:IM-11696-132	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)	refseq:NP_061153.1|ensembl:ENSG00000124226(gene)|ensembl:ENST00000244061(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR034734|interpro:IPR042716|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ZSC3lfWt9Fx/FDRYJO3WbVWn4Bs9606	rogid:R1fX8xaGuIhy/M6cLzPeyfJBf649606	intact-crc:058FFF6261CA0A78|rigid:1zLTmRK3prjTAY8LeIIhcQFg/i4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13064	uniprotkb:B3KSH4	intact:EBI-2340269|ensembl:ENSP00000313881	intact:EBI-2340216	psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340981|imex:IM-11696-136	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:07D46BCA8A9A333F|rigid:5wwO2lCM+2HJvfOyhe8C4PxBhzw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:Q06587	intact:EBI-2340216	intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340975|imex:IM-11696-134	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606	intact-crc:3DF78FE78C2720FD|rigid:3Iq2IalxWn0DcUKZssYewZ/v+/M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:P78317	intact:EBI-2340216	intact:EBI-2340927|uniprotkb:Q49AR8|uniprotkb:B2R6D6|uniprotkb:D6RF58|intact:EBI-28970119|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:rnf4_human(display_long)|uniprotkb:SNURF(gene name synonym)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:RNF4(gene name)|psi-mi:RNF4(display_short)|uniprotkb:RES4-26(orf name)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340978|imex:IM-11696-135	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:NP_001171938.1|refseq:NP_001171939.1|refseq:NP_002929.1|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503|ensembl:ENST00000511859|ensembl:ENSP00000426615|ensembl:ENST00000541204|ensembl:ENSP00000446369|ensembl:ENSG00000063978(gene)|ensembl:ENST00000314289(transcript)|ensembl:ENST00000506706(transcript)|ensembl:ENST00000511600(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|go:"GO:1990752"(microtubule end)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|mint:P78317|rcsb pdb:2EA6|rcsb pdb:2XEU|rcsb pdb:4PPE|reactome:R-HSA-5693607|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:Yhu2iAaNQYcfGdYohDPBdhMFEpc9606	intact-crc:0BD4AF5B4806C664|rigid:wMG2cKfApQOBJD14YN+LGM/AYGE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86Y13	uniprotkb:B3KSH4	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	intact:EBI-2340216	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340984|imex:IM-11696-137	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:C44B68A174DE6226|rigid:7+oWVRfFnGKgOVCL1oBIfCM8F/k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P50876	uniprotkb:B3KSH4	intact:EBI-2340657|uniprotkb:Q585H5|uniprotkb:D6W4Y6|ensembl:ENSP00000321330	intact:EBI-2340216	psi-mi:r144a_human(display_long)|uniprotkb:RNF144A(gene name)|psi-mi:RNF144A(display_short)|uniprotkb:KIAA0161(gene name synonym)|uniprotkb:RNF144(gene name synonym)|uniprotkb:UBCE7IP4(gene name synonym)|uniprotkb:RING finger protein 144A(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 4(gene name synonym)|uniprotkb:UbcM4-interacting protein 4(gene name synonym)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340987|imex:IM-11696-138	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055561.2|refseq:XP_016860885.1|refseq:XP_005246257.1|refseq:XP_005246259.1|refseq:XP_016860886.1|ensembl:ENSG00000151692(gene)|ensembl:ENST00000320892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031127|interpro:IPR044066|mint:P50876|rcsb pdb:1WIM|rcsb pdb:6L99|reactome:R-HSA-8866654	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:i2Ls6RkN4dTdPkBoso7ZDyIqi+g9606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:05EC0C81FC234536|rigid:FPiznPSzpngOjCJ0wE27w6tFPGc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H4P4	uniprotkb:B3KSH4	intact:EBI-2130266|uniprotkb:B2RBT8|uniprotkb:O75598|intact:EBI-2563208|intact:EBI-11576203|uniprotkb:A6NFW0|ensembl:ENSP00000342755|ensembl:ENSP00000447303|ensembl:ENSP00000484671	intact:EBI-2340216	psi-mi:rnf41_human(display_long)|uniprotkb:RNF41(gene name)|psi-mi:RNF41(display_short)|uniprotkb:FLRF(gene name synonym)|uniprotkb:NRDP1(gene name synonym)|uniprotkb:RING finger protein 41(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NRDP1(gene name synonym)|uniprotkb:SBBI03(orf name)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340990|imex:IM-11696-139	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011536036.1|refseq:XP_011536037.1|refseq:NP_001229755.1|refseq:NP_005776.1|refseq:NP_919340.1|refseq:NP_919339.1|refseq:XP_005268618.1|ensembl:ENSG00000181852(gene)|ensembl:ENST00000345093(transcript)|ensembl:ENST00000552656(transcript)|ensembl:ENST00000615206(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015036(USP8 interacting)|interpro:IPR017907|interpro:IPR037255|rcsb pdb:2FZP|rcsb pdb:2GWF|reactome:R-HSA-1358803|reactome:R-HSA-983168	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jthVZwxUECSdqeJ2jZQ5UL28kDY9606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:D3A959A17438FFEC|rigid:/GY9mNIYpfzjPrqHDeA/b+Wu5zc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:Q9BZY9	intact:EBI-2340216	intact:EBI-747544|uniprotkb:Q53H52|uniprotkb:Q5RI37|uniprotkb:Q5SRJ7|uniprotkb:Q5SRJ8|uniprotkb:Q5SS28|uniprotkb:Q96AK4|uniprotkb:Q96AP8|uniprotkb:Q99579|uniprotkb:Q9BZY8|uniprotkb:A6NLX6|uniprotkb:A9R9Q4|ensembl:ENSP00000350182|ensembl:ENSP00000365924|ensembl:ENSP00000390551|ensembl:ENSP00000391685|ensembl:ENSP00000398677|ensembl:ENSP00000409501	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:tri31_human(display_long)|uniprotkb:TRIM31(gene name)|psi-mi:TRIM31(display_short)|uniprotkb:C6orf13(gene name synonym)|uniprotkb:RNF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 31(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM31(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340999|imex:IM-11696-142	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:NP_008959.3|ensembl:ENSG00000137397(gene)|ensembl:ENSG00000204616(gene)|ensembl:ENSG00000223531(gene)|ensembl:ENSG00000224168(gene)|ensembl:ENSG00000225130(gene)|ensembl:ENSG00000233573(gene)|ensembl:ENST00000357569(transcript)|ensembl:ENST00000376734(transcript)|ensembl:ENST00000433864(transcript)|ensembl:ENST00000445679(transcript)|ensembl:ENST00000449412(transcript)|ensembl:ENST00000453266(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR020457|rcsb pdb:2YSJ|rcsb pdb:2YSL|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:f7qMSpsjq1gDv+rl2o2BWpXhvKw9606	intact-crc:75BCBAFBE908EE4E|rigid:U9uPkaW9lqmcsa32bfdcCE8NVoE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BWF2	uniprotkb:B3KSH4	intact:EBI-1756205|uniprotkb:O00467|uniprotkb:B5BU84|uniprotkb:B5BUL3|intact:EBI-28986477|ensembl:ENSP00000328203	intact:EBI-2340216	psi-mi:traip_human(display_long)|uniprotkb:TRAIP(gene name)|psi-mi:TRAIP(display_short)|uniprotkb:RNF206(gene name synonym)|uniprotkb:TRIP(gene name synonym)|uniprotkb:RING finger protein 206(gene name synonym)|uniprotkb:TRAF-interacting protein(gene name synonym)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340993|imex:IM-11696-140	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005870.2|ensembl:ENSP00000328203|ensembl:ENSG00000183763(gene)|ensembl:ENST00000331456(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007165"(signal transduction)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090734"(site of DNA damage)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:4ZTD|reactome:R-HSA-983168	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:af6osyzc1Cw/atmwUPTR1f5usBE9606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:CFC1C77967604560|rigid:GQA4HhXF28J6bmfc71x9EhUbNRk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BYM8	uniprotkb:B3KSH4	intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632	intact:EBI-2340216	psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2340996|imex:IM-11696-141	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006453.1|refseq:NP_112506.2|ensembl:ENSG00000125826(gene)|ensembl:ENST00000356286(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR026261|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|dip:DIP-47737N	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:EC01B97E847DB0D9|rigid:ZR+XZwIwa3qZrZbMRlp60/ioRZ8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:Q9C040	intact:EBI-2340216	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341002|imex:IM-11696-143	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	intact-crc:5DA4EEC5A9023698|rigid:Cu18bpNoYLHA7BjGMu0W3KllLYs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H000	uniprotkb:B3KSH4	intact:EBI-2341005|uniprotkb:A6NIA2|uniprotkb:Q9BUY2|uniprotkb:B3KRC5|uniprotkb:Q96BD4|uniprotkb:Q8N391|uniprotkb:Q9NRY1|uniprotkb:B4DPR4|intact:EBI-11126681|ensembl:ENSP00000170447|ensembl:ENSP00000502893	intact:EBI-2340216	psi-mi:mkrn2_human(display_long)|uniprotkb:MKRN2(gene name)|psi-mi:MKRN2(display_short)|uniprotkb:RNF62(gene name synonym)|uniprotkb:RING finger protein 62(gene name synonym)|uniprotkb:HSPC070(orf name)|uniprotkb:RING-type E3 ubiquitin transferase makorin-2(gene name synonym)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341015|imex:IM-11696-144	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054879.3|refseq:NP_001258636.1|ensembl:ENSG00000075975(gene)|ensembl:ENST00000170447(transcript)|ensembl:ENST00000677816(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026293|interpro:IPR036855|interpro:IPR041367|mint:Q9H000	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ZI7Jr4Fd52sQnfeNXXcZ0NscyD89606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:27815D8B9DE0B8C5|rigid:wa5TL69Egou0gB6/dSzyNQoe9rY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9ULV8	uniprotkb:B3KSH4	intact:EBI-2341018|uniprotkb:Q9Y5Z3|uniprotkb:Q8N1E5|uniprotkb:Q9Y5Z2|intact:EBI-28975910|ensembl:ENSP00000494162	intact:EBI-2340216	psi-mi:cblc_human(display_long)|uniprotkb:CBLC(gene name)|psi-mi:CBLC(display_short)|uniprotkb:CBL3(gene name synonym)|uniprotkb:RNF57(gene name synonym)|uniprotkb:SH3-binding protein CBL-C(gene name synonym)|uniprotkb:SH3-binding protein CBL-3(gene name synonym)|uniprotkb:RING finger protein 57(gene name synonym)|uniprotkb:Signal transduction protein CBL-C(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CBL-C(gene name synonym)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341025|imex:IM-11696-145	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000341505|ensembl:ENSP00000340250|ensembl:ENSP00000494162|refseq:NP_001124324.1|refseq:NP_036248.3|ensembl:ENSG00000142273(gene)|ensembl:ENST00000647358(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|rcsb pdb:3OP0|rcsb pdb:3VRN|rcsb pdb:3VRO|rcsb pdb:3VRP|rcsb pdb:3VRQ|rcsb pdb:3VRR	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:syzTzR6RGJzLv2EpDirSrli4ghs9606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:78CFDE5CA30E8519|rigid:y7F8Z0QirhHhyy0YSHLfVNJMaOg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:Q9H6Y7	intact:EBI-2340216	intact:EBI-1055214|uniprotkb:Q6XYE0|uniprotkb:Q8NDC1|uniprotkb:Q9Y3V1|uniprotkb:D3DTK8|ensembl:ENSP00000262482|ensembl:ENSP00000458794|ensembl:ENSP00000459324|ensembl:ENSP00000460190	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:rn167_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF167(gene name synonym)|uniprotkb:RING finger protein 167(gene name synonym)|uniprotkb:RING105(gene name synonym)|uniprotkb:RNF167(gene name)|psi-mi:RNF167(display_short)|uniprotkb:LP2254(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341028|imex:IM-11696-146	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:NP_056343.1|refseq:NP_001307285.1|refseq:NP_001307286.1|refseq:NP_001307287.1|refseq:NP_001307288.1|refseq:NP_001307289.1|refseq:NP_001307290.1|refseq:NP_001307291.1|refseq:NP_001307292.1|refseq:NP_001307293.1|refseq:NP_001307294.1|ensembl:ENSG00000108523(gene)|ensembl:ENST00000262482(transcript)|ensembl:ENST00000571816(transcript)|ensembl:ENST00000572430(transcript)|ensembl:ENST00000575111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044744|refseq:XP_016879916.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:IHiUNkyGVw8fPM9DqsAd3JC/eRM9606	intact-crc:030F7096B28217FA|rigid:ZagToITI3e4gAFadkQxq4iMey84	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y508	uniprotkb:B3KSH4	intact:EBI-723587|uniprotkb:Q6N0B0|uniprotkb:B2RDQ9|uniprotkb:B4DWY5|uniprotkb:E1P627|ensembl:ENSP00000244061	intact:EBI-2340216	psi-mi:rn114_human(display_long)|uniprotkb:Zinc finger protein 313(gene name synonym)|uniprotkb:RNF114(gene name)|psi-mi:RNF114(display_short)|uniprotkb:ZNF313(gene name synonym)|uniprotkb:ZNF228(gene name synonym)|uniprotkb:Zinc finger protein 228(gene name synonym)|uniprotkb:RING finger protein 114(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF114(gene name synonym)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341037|imex:IM-11696-149	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061153.1|ensembl:ENSG00000124226(gene)|ensembl:ENST00000244061(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR034734|interpro:IPR042716|reactome:R-HSA-983168	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:R1fX8xaGuIhy/M6cLzPeyfJBf649606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:DA6B8178040C9FBE|rigid:TVzrIAagK8VcIa9tXpw5/ojYuFQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BYJ4	uniprotkb:B3KSH4	intact:EBI-2130393|uniprotkb:Q9C016|uniprotkb:Q9HCR0|uniprotkb:Q9HCR1|uniprotkb:Q9HCR2|uniprotkb:D3DQS7|ensembl:ENSP00000402595|ensembl:ENSP00000422947	intact:EBI-2340216	psi-mi:tri34_human(display_long)|uniprotkb:TRIM34(gene name)|psi-mi:TRIM34(display_short)|uniprotkb:IFP1(gene name synonym)|uniprotkb:RNF21(gene name synonym)|uniprotkb:Interferon-responsive finger protein 1(gene name synonym)|uniprotkb:RING finger protein 21(gene name synonym)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341031|imex:IM-11696-147	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003827.1|refseq:NP_067629.2|refseq:NP_569074.2|ensembl:ENSG00000258659(gene)|ensembl:ENST00000429814(transcript)|ensembl:ENST00000514226(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035826|interpro:IPR043136|rcsb pdb:2EGP|reactome:R-HSA-877300|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:PaECx+owV1KulNUfKqjYKlB822g9606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:BEA639AC21BC8DC6|rigid:ZJdKKXpYOo5PzDYS6z6CXeBDW4s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:Q6ZNA4	intact:EBI-2340216	intact:EBI-2129175|uniprotkb:Q6ZMU2|uniprotkb:Q7L428|uniprotkb:Q7Z346|uniprotkb:Q8N1P9|uniprotkb:Q8WUA3|uniprotkb:Q9NSR1|uniprotkb:Q6P9A4|uniprotkb:C9JUS4|uniprotkb:H0YN55|ensembl:ENSP00000452732|intact:EBI-28970158	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:rn111_human(display_long)|uniprotkb:RNF111(gene name)|psi-mi:RNF111(display_short)|uniprotkb:RING finger protein 111(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Arkadia(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341034|imex:IM-11696-148	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:NP_060080.6|ensembl:ENST00000348370|ensembl:ENSP00000288199|ensembl:ENSP00000452732|ensembl:ENST00000559209|ensembl:ENSP00000453872|ensembl:ENST00000561186|ensembl:ENSP00000453015|refseq:NP_001317260.1|refseq:XP_016877827.1|refseq:XP_006720642.1|refseq:NP_001257459.1|refseq:NP_001257457.1|refseq:NP_001257458.1|ensembl:ENSG00000157450(gene)|ensembl:ENST00000557998(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR029306|rcsb pdb:2KIZ|rcsb pdb:5LG0|rcsb pdb:5LG7|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-5696395|reactome:R-HSA-983168|go:"GO:0032184"(SUMO polymer binding)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:6SY5oMr5u4mnVi+zdRboVljMGa09606	intact-crc:BF3182EAC67B4D8E|rigid:jgnX+YmwPXD2aegvBqyvKAxk1Aw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:Q9HCM9	intact:EBI-2340216	intact:EBI-739510|uniprotkb:Q5STG4|uniprotkb:Q76BL3|uniprotkb:Q8IYT9|uniprotkb:Q96IB6|ensembl:ENSP00000365844|ensembl:ENSP00000373096|ensembl:ENSP00000379796|ensembl:ENSP00000391917|ensembl:ENSP00000397043|ensembl:ENSP00000398355|ensembl:ENSP00000409902|ensembl:ENSP00000411949|ensembl:ENSP00000447835|ensembl:ENSP00000448462|ensembl:ENSP00000448572|ensembl:ENSP00000449272|ensembl:ENSP00000449847|ensembl:ENSP00000450288|uniprotkb:Q5STG3	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:tri39_human(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341040|imex:IM-11696-150	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376656(transcript)|ensembl:ENST00000383602(transcript)|ensembl:ENST00000396547(transcript)|ensembl:ENST00000413715(transcript)|ensembl:ENST00000424575(transcript)|ensembl:ENST00000445206(transcript)|ensembl:ENST00000426469(transcript)|ensembl:ENST00000451715(transcript)|ensembl:ENST00000547030(transcript)|ensembl:ENST00000548002(transcript)|ensembl:ENST00000549841(transcript)|ensembl:ENST00000550282(transcript)|ensembl:ENST00000552337(transcript)|ensembl:ENST00000552520(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035033|interpro:IPR043136|mint:Q9HCM9|rcsb pdb:2DID|rcsb pdb:2DIF|rcsb pdb:2ECJ|reactome:R-HSA-983168|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_067076.2|refseq:NP_742013.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:xMCXGcMTqCjzLQzC53o81S4gqZA9606	intact-crc:F74FB93080EDE015|rigid:PXqH7gXDxsLDKh6wK3JX7f/MWDY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CA5	uniprotkb:B3KSH4	intact:EBI-517623|uniprotkb:Q9BQV0|uniprotkb:Q9H2A8|uniprotkb:Q9HAP7|ensembl:ENSP00000217169	intact:EBI-2340216	psi-mi:birc7_human(display_long)|uniprotkb:Kidney inhibitor of apoptosis protein(gene name synonym)|uniprotkb:Melanoma inhibitor of apoptosis protein(gene name synonym)|uniprotkb:Livin(gene name synonym)|uniprotkb:RING finger protein 50(gene name synonym)|uniprotkb:UNQ5800/PRO19607/PRO21344(orf name)|uniprotkb:BIRC7(gene name)|psi-mi:BIRC7(display_short)|uniprotkb:KIAP(gene name synonym)|uniprotkb:LIVIN(gene name synonym)|uniprotkb:MLIAP(gene name synonym)|uniprotkb:RNF50(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC7(gene name synonym)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341043|imex:IM-11696-151	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071444.1|refseq:NP_647478.1|dip:DIP-33486N|ensembl:ENSG00000101197(gene)|ensembl:ENST00000217169(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070247"(regulation of natural killer cell apoptotic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:1OXN|rcsb pdb:1OXQ|rcsb pdb:1OY7|rcsb pdb:1TW6|rcsb pdb:2I3H|rcsb pdb:2I3I|rcsb pdb:3F7G|rcsb pdb:3F7H|rcsb pdb:3F7I|rcsb pdb:3GT9|rcsb pdb:3GTA|rcsb pdb:3UW5|rcsb pdb:4AUQ	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hXh11nqcUM5IFQL3tS2/czb4lyA9606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:C2DD5B86036DA9CF|rigid:qcHGzWXaLcRsAVakjx356oqiuhA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:Q6Q0C0	intact:EBI-2340216	intact:EBI-307556|uniprotkb:Q9H073|ensembl:ENSP00000318944	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:traf7_human(display_long)|uniprotkb:TRAF7(gene name)|psi-mi:TRAF7(display_short)|uniprotkb:TNF receptor-associated factor 7(gene name synonym)|uniprotkb:RING finger and WD repeat-containing protein 1(gene name synonym)|uniprotkb:RING finger protein 119(gene name synonym)|uniprotkb:RFWD1(gene name synonym)|uniprotkb:RNF119(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341046|imex:IM-11696-152	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:NP_115647.2|ensembl:ENSG00000131653(gene)|ensembl:ENST00000326181(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017907|interpro:IPR019775|interpro:IPR020472|interpro:IPR027370|interpro:IPR036322|mint:Q6Q0C0|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:46dtsS1OairncB0fnINSW1aY2789606	intact-crc:D940391B87502FF4|rigid:1QpF/HPh62Ye+GUYv6+THi1Vsss	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C035	uniprotkb:B3KSH4	intact:EBI-924214|uniprotkb:Q2MLV4|uniprotkb:Q2MLV8|uniprotkb:Q2MLV9|uniprotkb:Q2MLW1|uniprotkb:Q2MLW3|uniprotkb:Q2MLW4|uniprotkb:A6NGQ1|uniprotkb:Q2MLW6|uniprotkb:Q2MLW7|uniprotkb:Q2MLX1|uniprotkb:Q2MLX2|uniprotkb:Q2MLX3|uniprotkb:Q2MLX5|uniprotkb:Q2MLY3|uniprotkb:Q2MLY4|uniprotkb:Q2V6Q6|uniprotkb:Q6GX26|uniprotkb:Q8WU46|uniprotkb:Q96SR5|uniprotkb:Q9C031|uniprotkb:Q9C032|uniprotkb:Q9C033|uniprotkb:Q9C034|uniprotkb:A8WFA8|uniprotkb:D3DQS8|uniprotkb:D3DQS9|uniprotkb:G3GJY1|ensembl:ENSP00000369373|ensembl:ENSP00000507420	intact:EBI-2340216	psi-mi:trim5_human(display_long)|uniprotkb:TRIM5(gene name)|psi-mi:TRIM5(display_short)|uniprotkb:RNF88(gene name synonym)|uniprotkb:RING finger protein 88(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM5(gene name synonym)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341049|imex:IM-11696-153	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149023.2|refseq:NP_149083.2|refseq:NP_149084.2|refseq:XP_011518729.1|refseq:XP_005253240.1|refseq:XP_005253241.1|ensembl:ENSG00000132256(gene)|ensembl:ENST00000380034(transcript)|ensembl:ENST00000684655(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031664"(regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR043136|rcsb pdb:2ECV|rcsb pdb:2YRG|reactome:R-HSA-877300	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:t0YqhaJC8oQcwot7oks1LgMxdNc9606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:9F9698B79AC564EE|rigid:Zux9wUtLTEaqPvvCHmfQUJGBr/k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6UWE0	uniprotkb:B3KSH4	intact:EBI-720984|uniprotkb:Q5VVV0|uniprotkb:Q8NB40|uniprotkb:Q96GT5|uniprotkb:Q96MX5|uniprotkb:Q96MZ7|ensembl:ENSP00000300417|ensembl:ENSP00000322937|ensembl:ENSP00000362419|ensembl:ENSP00000502167	intact:EBI-2340216	psi-mi:lrsm1_human(display_long)|uniprotkb:Leucine-rich repeat and sterile alpha motif-containing protein 1(gene name synonym)|uniprotkb:Tsg101-associated ligase(gene name synonym)|uniprotkb:LRSAM1(gene name)|psi-mi:LRSAM1(display_short)|uniprotkb:TAL(gene name synonym)|uniprotkb:UNQ6496/PRO21356(orf name)|uniprotkb:RING-type E3 ubiquitin transferase LRSAM1(gene name synonym)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341052|imex:IM-11696-154	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005373.1|refseq:NP_001005374.1|refseq:NP_001177652.1|refseq:NP_612370.3|refseq:XP_016870772.1|ensembl:ENSG00000148356(gene)|ensembl:ENST00000300417(transcript)|ensembl:ENST00000323301(transcript)|ensembl:ENST00000373322(transcript)|ensembl:ENST00000675448(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0046755"(viral budding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032675|mint:Q6UWE0|reactome:R-HSA-983168	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:qkwPqOsfNjZBB2Xp6YAA9FbEZxM9606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:9586503BBFF832C4|rigid:He3BD3xmJLEk6P5itTl4OX+Vmos	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:Q96P09	intact:EBI-2340216	intact:EBI-2341055|uniprotkb:Q96RW5|uniprotkb:Q6IPY1	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:birc8_human(display_long)|uniprotkb:BIRC8(gene name)|psi-mi:BIRC8(display_short)|uniprotkb:ILP2(gene name synonym)|uniprotkb:Inhibitor of apoptosis-like protein 2(gene name synonym)|uniprotkb:Testis-specific inhibitor of apoptosis(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341061|imex:IM-11696-155	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	interpro:IPR042579|refseq:NP_203127.3|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:1XB0|rcsb pdb:1XB1|interpro:IPR011029(DEATH-like)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:dNa54zbu4SMSRJ8FXGBLuqGJ0qo9606	intact-crc:272979C42514249D|rigid:PLqQ2kOot5zW3EoVo2NXprLXssE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:Q86UD3	intact:EBI-2340216	intact:EBI-2341065|uniprotkb:A8K264|uniprotkb:B9EJE7|ensembl:ENSP00000309141	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:marh3_human(display_long)|uniprotkb:MARCHF3(gene name)|psi-mi:MARCHF3(display_short)|uniprotkb:MARCH3(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 3(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein III(gene name synonym)|uniprotkb:RING finger protein 173(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF3(gene name synonym)|uniprotkb:RNF173(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341064|imex:IM-11696-402	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:NP_848545.1|ensembl:ENSG00000173926(gene)|ensembl:ENST00000308660(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:uv/JcWUoL549NACFaOUs/oLdHuI9606	intact-crc:B7DD9A31A23647C0|rigid:nwJfXMh8PK3nE+DiiRAG65FJJjs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:Q9H0A6	intact:EBI-2340216	intact:EBI-724829|uniprotkb:Q6FIB3|uniprotkb:Q6X7T4|uniprotkb:Q8N6V8|uniprotkb:Q8TDG0|uniprotkb:Q96BM5|uniprotkb:Q9Y6U1|ensembl:ENSP00000315950|ensembl:ENSP00000376499|ensembl:ENSP00000385285|ensembl:ENSP00000405588	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:rnf32_human(display_long)|uniprotkb:RNF32(gene name)|psi-mi:RNF32(display_short)|uniprotkb:HSD15(orf name)|uniprotkb:FKSG33(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341078|imex:IM-11696-405	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:NP_001171925.1|refseq:NP_001171926.1|refseq:NP_112198.1|ensembl:ENSG00000105982(gene)|ensembl:ENST00000317955(transcript)|ensembl:ENST00000392743(transcript)|ensembl:ENST00000405335(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0046872"(metal ion binding)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR027370|interpro:IPR042862|ensembl:ENST00000432459(transcript)|refseq:XP_011514108.1|refseq:XP_011514109.1|refseq:XP_011514110.1|refseq:NP_001295202.1|refseq:NP_001295203.1|refseq:XP_011514106.1|refseq:XP_011514111.1|refseq:XP_011514107.1|refseq:XP_005249579.1|refseq:XP_011514112.1|refseq:XP_011514113.1|refseq:XP_011514114.1|refseq:XP_016867244.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:9moHSrgbI9uQFEse3AXsdV7U/HE9606	intact-crc:CE4794B25A12A9E7|rigid:vNjLombgYcOw6S2siBuuaxXI3IE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:Q96PU4	intact:EBI-2340216	intact:EBI-625304|uniprotkb:Q5VYR1|uniprotkb:Q5VYR3|uniprotkb:Q659C8|uniprotkb:Q8TAG7|ensembl:ENSP00000276893	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:uhrf2_human(display_long)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 2(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 2(gene name synonym)|uniprotkb:Np95/ICBP90-like RING finger protein(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np97(gene name synonym)|uniprotkb:RING finger protein 107(gene name synonym)|uniprotkb:UHRF2(gene name)|psi-mi:UHRF2(display_short)|uniprotkb:NIRF(gene name synonym)|uniprotkb:RNF107(gene name synonym)|uniprotkb:Nuclear protein 97(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341072|imex:IM-11696-403	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:NP_690856.1|ensembl:ENSG00000147854(gene)|ensembl:ENST00000276893(transcript)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|rcsb pdb:1WY8|rcsb pdb:1Z6U|rcsb pdb:2E6S|rcsb pdb:3OLN|rcsb pdb:4PW5|rcsb pdb:4PW6|rcsb pdb:4PW7|rcsb pdb:4TVR|rcsb pdb:5YCO|reactome:R-HSA-3899300|interpro:IPR001841(Zinc finger, RING-type)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007049"(cell cycle)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000626(Ubiquitin)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:zXJPI7UvOPWn2fsgF5/RdIUMc749606	intact-crc:BADA5909D419FAE3|rigid:/nX83CFnCzFkuiEsobqlP3VfKJY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B3KSH4	uniprotkb:Q96BQ3	intact:EBI-2340216	intact:EBI-2129899|uniprotkb:Q53TJ7|ensembl:ENSP00000272395	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:tri43_human(display_long)|uniprotkb:TRIM43(gene name)|psi-mi:TRIM43(display_short)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341075|imex:IM-11696-404	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	refseq:NP_620155.1|ensembl:ENSG00000144015(gene)|ensembl:ENST00000272395(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0045087"(innate immune response)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR043136	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	rogid:pfo60amX0NFspl9zqQ/Cgek6yO09606	intact-crc:E3A408ECCB199D22|rigid:wS3RRX5bk/QPBA14pi7knxnP6rI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TDB6	uniprotkb:B3KSH4	intact:EBI-2340392|uniprotkb:Q5MJP7|uniprotkb:Q53ZZ3|uniprotkb:B3KWH6|ensembl:ENSP00000296161	intact:EBI-2340216	psi-mi:dtx3l_human(display_long)|uniprotkb:DTX3L(gene name)|psi-mi:DTX3L(display_short)|uniprotkb:BBAP(gene name synonym)|uniprotkb:B-lymphoma- and BAL-associated protein(gene name synonym)|uniprotkb:Rhysin-2(gene name synonym)|uniprotkb:Protein deltex-3-like(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3L(gene name synonym)	psi-mi:b3ksh4_human(display_long)|uniprotkb:HIP2(gene name)|psi-mi:HIP2(display_short)|uniprotkb:hCG_38552(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341081|imex:IM-11696-406	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612144.1|ensembl:ENSG00000163840(gene)|ensembl:ENST00000296161(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0015031"(protein transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:2000646"(positive regulation of receptor catabolic process)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|interpro:IPR042843|rcsb pdb:3PG6|reactome:R-HSA-983168	interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001299576.1|refseq:NP_001299577.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:d2ctDfd7pj1wRA3HxmyWJ5nL19Y9606	rogid:RE4P7KDjFjL4dTNfSHU9vEd48yg9606	intact-crc:EF7E82B62BFF977B|rigid:SngSDFfGqCB7edoHGKVV+UTruOM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q6ZNA4	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-2129175|uniprotkb:Q6ZMU2|uniprotkb:Q7L428|uniprotkb:Q7Z346|uniprotkb:Q8N1P9|uniprotkb:Q8WUA3|uniprotkb:Q9NSR1|uniprotkb:Q6P9A4|uniprotkb:C9JUS4|uniprotkb:H0YN55|ensembl:ENSP00000452732|intact:EBI-28970158	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:rn111_human(display_long)|uniprotkb:RNF111(gene name)|psi-mi:RNF111(display_short)|uniprotkb:RING finger protein 111(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Arkadia(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341084|imex:IM-11696-407	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_060080.6|ensembl:ENST00000348370|ensembl:ENSP00000288199|ensembl:ENSP00000452732|ensembl:ENST00000559209|ensembl:ENSP00000453872|ensembl:ENST00000561186|ensembl:ENSP00000453015|refseq:NP_001317260.1|refseq:XP_016877827.1|refseq:XP_006720642.1|refseq:NP_001257459.1|refseq:NP_001257457.1|refseq:NP_001257458.1|ensembl:ENSG00000157450(gene)|ensembl:ENST00000557998(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR029306|rcsb pdb:2KIZ|rcsb pdb:5LG0|rcsb pdb:5LG7|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-5696395|reactome:R-HSA-983168|go:"GO:0032184"(SUMO polymer binding)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:6SY5oMr5u4mnVi+zdRboVljMGa09606	intact-crc:B422A6CB1CF59375|rigid:8qt1X99WpSkeNCvytHe3Hq8chbw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q9NS91	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-2339393|uniprotkb:Q9NRT6|uniprotkb:Q58F55|ensembl:ENSP00000264926	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:rad18_human(display_long)|uniprotkb:RAD18(gene name)|psi-mi:RAD18(display_short)|uniprotkb:RNF73(gene name synonym)|uniprotkb:Postreplication repair protein RAD18(gene name synonym)|uniprotkb:RING finger protein 73(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RAD18(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341087|imex:IM-11696-408	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_064550.3|ensembl:ENSP00000264926|dip:DIP-29831N|ensembl:ENSG00000070950(gene)|ensembl:ENST00000264926(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097505"(Rad6-Rad18 complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036361|interpro:IPR039577|mint:Q9NS91|rcsb pdb:2MRE|rcsb pdb:2MRF|rcsb pdb:2Y43|rcsb pdb:2YBF|rcsb pdb:5VF0|reactome:R-HSA-110314|reactome:R-HSA-8866654|go:"GO:0060548"(negative regulation of cell death)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:/HmKCLqG1BxzmIWCgVpOw/gzJc49606	intact-crc:1634431DD18CFC1B|rigid:eGOHEzgzkNVzVcepppGCn4CBWng	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99816	uniprotkb:Q7Z4K8	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-723344|uniprotkb:Q6NT17|uniprotkb:Q6NT41|uniprotkb:Q6ZRL7|uniprotkb:Q9H5P2|ensembl:ENSP00000334657|uniprotkb:A0AVI6|uniprotkb:Q5VT60|uniprotkb:Q5VT62|uniprotkb:B1AVQ4	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:tri46_human(display_long)|uniprotkb:Tripartite, fibronectin type-III and C-terminal SPRY motif protein(gene name synonym)|uniprotkb:Gene Y protein(gene name synonym)|uniprotkb:TRIM46(gene name)|psi-mi:TRIM46(display_short)|uniprotkb:TRIFIC(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341090|imex:IM-11696-409	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_079334.3|ensembl:ENSG00000163462(gene)|ensembl:ENST00000334634(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001764"(neuron migration)|interpro:IPR027370|interpro:IPR035731|interpro:IPR036116|interpro:IPR040859|interpro:IPR043136|reactome:R-HSA-877300|go:"GO:0005856"(cytoskeleton)|go:"GO:0007409"(axonogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0043194"(axon initial segment)|go:"GO:0044304"(main axon)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0099612"(protein localization to axon)|go:"GO:1901953"(positive regulation of anterograde dense core granule transport)|go:"GO:1903827"|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990769"(proximal neuron projection)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|refseq:NP_001243528.1|refseq:NP_001243529.1|refseq:NP_001243530.1|refseq:NP_001269307.1|refseq:NP_001269308.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:Te5aeDC5aMKYNhajjekIRJCtzBQ9606	intact-crc:F950EABB8C5F3ADA|rigid:9HmQ9NIy8DaN25ZNJAB2Dx+ClIo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49459	uniprotkb:P14373	intact:EBI-2339348|uniprotkb:A6NMF5|uniprotkb:Q96FX4|uniprotkb:B2R7R9|uniprotkb:Q4TTG1|uniprotkb:D3DWI1|uniprotkb:A6NFE9|uniprotkb:A6NGR2|ensembl:ENSP00000360613	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:ube2a_human(display_long)|uniprotkb:UBE2A(gene name)|psi-mi:UBE2A(display_short)|uniprotkb:RAD6A(gene name synonym)|uniprotkb:Ubiquitin-protein ligase A(gene name synonym)|uniprotkb:Ubiquitin carrier protein A(gene name synonym)|uniprotkb:RAD6 homolog A(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme A(gene name synonym)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341093|imex:IM-11696-410	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003327.2|refseq:NP_861427.1|refseq:NP_001269090.1|dip:DIP-24260N|ensembl:ENSG00000077721(gene)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033503"(HULC complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P49459|rcsb pdb:6CYO|rcsb pdb:6CYR|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|ensembl:ENST00000371558(transcript)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:T6Mzgy6RHO9HoEIG3FmQvsP32vU9606	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:C1A6937C825411EF|rigid:Xfmp1RlfUkNLRv2fCBKbqJPKhN0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49459	uniprotkb:Q6ZT12	intact:EBI-2339348|uniprotkb:A6NMF5|uniprotkb:Q96FX4|uniprotkb:B2R7R9|uniprotkb:Q4TTG1|uniprotkb:D3DWI1|uniprotkb:A6NFE9|uniprotkb:A6NGR2|ensembl:ENSP00000360613	intact:EBI-2341096|uniprotkb:Q6ZSC2|uniprotkb:Q6ZR55|uniprotkb:Q8ND96|uniprotkb:B4DZR7|uniprotkb:Q8IVE7|uniprotkb:Q2KHN5|ensembl:ENSP00000272793	psi-mi:ube2a_human(display_long)|uniprotkb:UBE2A(gene name)|psi-mi:UBE2A(display_short)|uniprotkb:RAD6A(gene name synonym)|uniprotkb:Ubiquitin-protein ligase A(gene name synonym)|uniprotkb:Ubiquitin carrier protein A(gene name synonym)|uniprotkb:RAD6 homolog A(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme A(gene name synonym)	psi-mi:ubr3_human(display_long)|uniprotkb:UBR3(gene name)|psi-mi:UBR3(display_short)|uniprotkb:KIAA2024(gene name synonym)|uniprotkb:ZNF650(gene name synonym)|uniprotkb:N-recognin-3(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3-alpha-3(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3-alpha-III(gene name synonym)|uniprotkb:Zinc finger protein 650(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341107|imex:IM-11696-411	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003327.2|refseq:NP_861427.1|refseq:NP_001269090.1|dip:DIP-24260N|ensembl:ENSG00000077721(gene)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033503"(HULC complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P49459|rcsb pdb:6CYO|rcsb pdb:6CYR|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|ensembl:ENST00000371558(transcript)	refseq:NP_742067.3|ensembl:ENSG00000144357(gene)|ensembl:ENST00000272793(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR039164|interpro:IPR044046	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:T6Mzgy6RHO9HoEIG3FmQvsP32vU9606	rogid:96hvp16/7G0ErwWa7lDanCpru5I9606	intact-crc:05F2B95342765DDA|rigid:YV74Bi3b2O9/tQuYKaJiF+J36ds	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6ZT12	uniprotkb:P63146	intact:EBI-2341096|uniprotkb:Q6ZSC2|uniprotkb:Q6ZR55|uniprotkb:Q8ND96|uniprotkb:B4DZR7|uniprotkb:Q8IVE7|uniprotkb:Q2KHN5|ensembl:ENSP00000272793	intact:EBI-712629|uniprotkb:P23567|uniprotkb:Q4PJ15|ensembl:ENSP00000265339|uniprotkb:Q9D0J6|uniprotkb:B2R503|uniprotkb:D3DQA2	psi-mi:ubr3_human(display_long)|uniprotkb:UBR3(gene name)|psi-mi:UBR3(display_short)|uniprotkb:KIAA2024(gene name synonym)|uniprotkb:ZNF650(gene name synonym)|uniprotkb:N-recognin-3(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3-alpha-3(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3-alpha-III(gene name synonym)|uniprotkb:Zinc finger protein 650(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR3(gene name synonym)	psi-mi:ube2b_human(display_long)|uniprotkb:Ubiquitin-protein ligase B(gene name synonym)|uniprotkb:Ubiquitin carrier protein B(gene name synonym)|uniprotkb:RAD6 homolog B(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa(gene name synonym)|uniprotkb:UBE2B(gene name)|psi-mi:UBE2B(display_short)|uniprotkb:RAD6B(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme B(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341110|imex:IM-11696-412	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_742067.3|ensembl:ENSG00000144357(gene)|ensembl:ENST00000272793(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR039164|interpro:IPR044046	ensembl:ENSG00000119048(gene)|ensembl:ENST00000265339(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001741"(XY body)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0009411"(response to UV)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR023313|mint:P63146|rcsb pdb:1JAS|rcsb pdb:1NXA|rcsb pdb:2Y4W|rcsb pdb:2YB6|rcsb pdb:2YBF|reactome:R-HSA-110314|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0033503"(HULC complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0050821"(protein stabilization)|go:"GO:0051026"(chiasma assembly)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070076"(histone lysine demethylation)|go:"GO:0070193"(synaptonemal complex organization)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070829"(obsolete heterochromatin maintenance)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|refseq:NP_003328.1|dip:DIP-29832N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:96hvp16/7G0ErwWa7lDanCpru5I9606	rogid:JvcUPH+3qQXicPsIRFnW19NOc3c9606	intact-crc:959D9ACC79490A31|rigid:k266/jQtY2eSUMY/Zb9Jt7AMWp4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKV5	uniprotkb:P51668	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341113|imex:IM-11696-413	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:E189D17D90AEB3ED|rigid:bL45AfRN4s8DzUlAvsmvi8sMdis	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06587	uniprotkb:P51668	intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341116|imex:IM-11696-414	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:4FBAF986C270976B|rigid:/xAVjqSLqL+aaPPV4ZjZCfZkLZA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q8IUQ4	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-747107|uniprotkb:O43269|uniprotkb:Q49A58|uniprotkb:A0FKF3|uniprotkb:Q92880|ensembl:ENSP00000369343|ensembl:ENSP00000378214|ensembl:ENSP00000456421	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:siah1_human(display_long)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341122|imex:IM-11696-157	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:XP_006721309.1|refseq:NP_001006611.1|refseq:NP_003022.3|refseq:XP_011521581.1|ensembl:ENST00000380006(transcript)|ensembl:ENST00000394725(transcript)|ensembl:ENST00000568007(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|mint:Q8IUQ4|rcsb pdb:2A25|rcsb pdb:4C9Z|rcsb pdb:4CA1|rcsb pdb:4I7B|rcsb pdb:4I7C|rcsb pdb:4I7D|rcsb pdb:4X3G|rcsb pdb:5WZZ|reactome:R-HSA-373752|reactome:R-HSA-977225|reactome:R-HSA-983168|ensembl:ENSG00000196470(gene)|dip:DIP-35684N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:O6+z1g9K1ij87Xgo5/Ykl5Q3vUQ9606	intact-crc:FCBC2BEA6960BE45|rigid:i4GA2dOkHDJT4XOFISwN5K/h6oU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P78317	uniprotkb:P51668	intact:EBI-2340927|uniprotkb:Q49AR8|uniprotkb:B2R6D6|uniprotkb:D6RF58|intact:EBI-28970119|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:rnf4_human(display_long)|uniprotkb:SNURF(gene name synonym)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:RNF4(gene name)|psi-mi:RNF4(display_short)|uniprotkb:RES4-26(orf name)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341119|imex:IM-11696-156	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171938.1|refseq:NP_001171939.1|refseq:NP_002929.1|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503|ensembl:ENST00000511859|ensembl:ENSP00000426615|ensembl:ENST00000541204|ensembl:ENSP00000446369|ensembl:ENSG00000063978(gene)|ensembl:ENST00000314289(transcript)|ensembl:ENST00000506706(transcript)|ensembl:ENST00000511600(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|go:"GO:1990752"(microtubule end)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|mint:P78317|rcsb pdb:2EA6|rcsb pdb:2XEU|rcsb pdb:4PPE|reactome:R-HSA-5693607|reactome:R-HSA-983168	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Yhu2iAaNQYcfGdYohDPBdhMFEpc9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:7999D93A065171F2|rigid:RIo2mmyZ2bfQzTKEMHFldRQUaAM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q9Y4K3	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|ensembl:ENSP00000337853|ensembl:ENSP00000433623|uniprotkb:D3DR16	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341125|imex:IM-11696-158	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_004611.1|refseq:NP_665802.1|ensembl:ENSG00000175104(gene)|ensembl:ENST00000348124(transcript)|ensembl:ENST00000526995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|go:"GO:0070534"(protein K63-linked ubiquitination)|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|go:"GO:0070555"(response to interleukin-1)|rcsb pdb:7L3L|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|go:"GO:0071222"(cellular response to lipopolysaccharide)|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-975871|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|dip:DIP-27515N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606	intact-crc:706C621AB3C6C6F1|rigid:1Xk3CbTQEwdXwrSFAN+Nn1HY/Iw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12899	uniprotkb:P51668	intact:EBI-2341136|intact:EBI-2802887|uniprotkb:A6NG96|uniprotkb:Q5SRL2|ensembl:ENSP00000331131|ensembl:ENSP00000373102|ensembl:ENSP00000379806|ensembl:ENSP00000389203|ensembl:ENSP00000390258|ensembl:ENSP00000391879|ensembl:ENSP00000392805|ensembl:ENSP00000393011|ensembl:ENSP00000394371|ensembl:ENSP00000394421|ensembl:ENSP00000395491|ensembl:ENSP00000396188|ensembl:ENSP00000398545|ensembl:ENSP00000402395|ensembl:ENSP00000406707|ensembl:ENSP00000407294|ensembl:ENSP00000407876|ensembl:ENSP00000408233|ensembl:ENSP00000409182|ensembl:ENSP00000410446|ensembl:ENSP00000414248|ensembl:ENSP00000415328|ensembl:ENSP00000415755|ensembl:ENSP00000416737	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:tri26_human(display_long)|uniprotkb:TRIM26(gene name)|psi-mi:TRIM26(display_short)|uniprotkb:RNF95(gene name synonym)|uniprotkb:ZNF173(gene name synonym)|uniprotkb:Zinc finger protein 173(gene name synonym)|uniprotkb:Acid finger protein(gene name synonym)|uniprotkb:RING finger protein 95(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341135|imex:IM-11696-416	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006715243.1|refseq:NP_001229712.1|refseq:NP_003440.1|refseq:XP_005249431.1|refseq:XP_005249432.1|refseq:XP_005249433.1|refseq:XP_005249434.1|refseq:XP_005249435.1|dip:DIP-52853N|ensembl:ENSG00000137313(gene)|ensembl:ENSG00000226060(gene)|ensembl:ENSG00000228881(gene)|ensembl:ENSG00000230230(gene)|ensembl:ENSG00000231002(gene)|ensembl:ENSG00000231641(gene)|ensembl:ENSG00000234046(gene)|ensembl:ENSG00000234127(gene)|ensembl:ENST00000327357(transcript)|ensembl:ENST00000383607(transcript)|ensembl:ENST00000396558(transcript)|ensembl:ENST00000415923(transcript)|ensembl:ENST00000422349(transcript)|ensembl:ENST00000425523(transcript)|ensembl:ENST00000425831(transcript)|ensembl:ENST00000427535(transcript)|ensembl:ENST00000428486(transcript)|ensembl:ENST00000432326(transcript)|ensembl:ENST00000433314(transcript)|ensembl:ENST00000436219(transcript)|ensembl:ENST00000437089(transcript)|ensembl:ENST00000438384(transcript)|ensembl:ENST00000438908(transcript)|ensembl:ENST00000439094(transcript)|ensembl:ENST00000445259(transcript)|ensembl:ENST00000447711(transcript)|ensembl:ENST00000450392(transcript)|ensembl:ENST00000453195(transcript)|ensembl:ENST00000454678(transcript)|ensembl:ENST00000455000(transcript)|ensembl:ENST00000456093(transcript)|ensembl:ENST00000456770(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR043136|mint:Q12899|reactome:R-HSA-877300	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:GPu3YgJ3xR1pN/MM9IKU3unCj1A9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:C258A8A13CFAF814|rigid:3uIdmBYPBDzFrJ9isXOx86SiOhw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14258	uniprotkb:P51668	intact:EBI-2341129|intact:EBI-28973868|ensembl:ENSP00000323889|ensembl:ENSP00000445961	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:tri25_human(display_long)|uniprotkb:TRIM25(gene name)|psi-mi:TRIM25(display_short)|uniprotkb:EFP(gene name synonym)|uniprotkb:RNF147(gene name synonym)|uniprotkb:ZNF147(gene name synonym)|uniprotkb:Zinc finger protein 147(gene name synonym)|uniprotkb:Estrogen-responsive finger protein(gene name synonym)|uniprotkb:RING finger protein 147(gene name synonym)|uniprotkb:Ubiquitin/ISG15-conjugating enzyme TRIM25(gene name synonym)|uniprotkb:Tripartite motif-containing protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM25(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341128|imex:IM-11696-415	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000323889|ensembl:ENSP00000445961|refseq:NP_005073.2|ensembl:ENSG00000121060(gene)|ensembl:ENST00000316881(transcript)|ensembl:ENST00000537230(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016604"(nuclear body)|go:"GO:0016874"(ligase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033280"(response to vitamin D)|go:"GO:0039552"(RIG-I binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043627"(response to estrogen)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|go:"GO:1902187"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042753|interpro:IPR043136|mint:Q14258|rcsb pdb:4CFG|rcsb pdb:4LTB|rcsb pdb:5EYA|rcsb pdb:5FER|rcsb pdb:5NT1|rcsb pdb:5NT2|rcsb pdb:6FLM|rcsb pdb:6FLN|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-5689896|reactome:R-HSA-877300|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:NhFfC0IxHvxPIt2YnKCPsPKuiQA9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:ECD8DD96C55D9699|rigid:NKod65kliu3pU3Zi4bDXpSbevlw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95376	uniprotkb:P51668	intact:EBI-711158|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9|ensembl:ENSP00000348769|ensembl:ENSP00000403222	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341145|imex:IM-11696-418	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|ensembl:ENSG00000177479(gene)|ensembl:ENST00000356401(transcript)|ensembl:ENST00000449376(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|refseq:XP_016861020.1|refseq:XP_016861021.1	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:082F930DC5E6D862|rigid:Tb6cXY7s0enX1gFW0u81CSamTFU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZY9	uniprotkb:P51668	intact:EBI-747544|uniprotkb:Q53H52|uniprotkb:Q5RI37|uniprotkb:Q5SRJ7|uniprotkb:Q5SRJ8|uniprotkb:Q5SS28|uniprotkb:Q96AK4|uniprotkb:Q96AP8|uniprotkb:Q99579|uniprotkb:Q9BZY8|uniprotkb:A6NLX6|uniprotkb:A9R9Q4|ensembl:ENSP00000350182|ensembl:ENSP00000365924|ensembl:ENSP00000390551|ensembl:ENSP00000391685|ensembl:ENSP00000398677|ensembl:ENSP00000409501	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:tri31_human(display_long)|uniprotkb:TRIM31(gene name)|psi-mi:TRIM31(display_short)|uniprotkb:C6orf13(gene name synonym)|uniprotkb:RNF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 31(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM31(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341148|imex:IM-11696-419	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008959.3|ensembl:ENSG00000137397(gene)|ensembl:ENSG00000204616(gene)|ensembl:ENSG00000223531(gene)|ensembl:ENSG00000224168(gene)|ensembl:ENSG00000225130(gene)|ensembl:ENSG00000233573(gene)|ensembl:ENST00000357569(transcript)|ensembl:ENST00000376734(transcript)|ensembl:ENST00000433864(transcript)|ensembl:ENST00000445679(transcript)|ensembl:ENST00000449412(transcript)|ensembl:ENST00000453266(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR020457|rcsb pdb:2YSJ|rcsb pdb:2YSL|reactome:R-HSA-877300	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:f7qMSpsjq1gDv+rl2o2BWpXhvKw9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:07F1CC9AA75F59D8|rigid:vR2tDGib74dfJfGtNJqtORt6tsw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBF6	uniprotkb:P51668	intact:EBI-398632|uniprotkb:Q9BXN8|uniprotkb:Q9Y5M7|uniprotkb:A8MTB5|uniprotkb:A8K1H9|uniprotkb:D3DNF7|uniprotkb:D3DNF8|uniprotkb:C9JYL3|ensembl:ENSP00000273480	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:rbx2_human(display_long)|uniprotkb:RNF7(gene name)|psi-mi:RNF7(display_short)|uniprotkb:RBX2(gene name synonym)|uniprotkb:ROC2(gene name synonym)|uniprotkb:SAG(gene name synonym)|uniprotkb:RING finger protein 7(gene name synonym)|uniprotkb:Regulator of cullins 2(gene name synonym)|uniprotkb:CKII beta-binding protein 1(gene name synonym)|uniprotkb:Sensitive to apoptosis gene protein(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341142|imex:IM-11696-417	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055060.1|refseq:NP_899060.1|refseq:NP_001188299.1|ensembl:ENSG00000114125(gene)|ensembl:ENST00000273480(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045116"(protein neddylation)|go:"GO:0051775"(response to redox state)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|rcsb pdb:2ECL|reactome:R-HSA-8951664|reactome:R-HSA-9705462|reactome:R-HSA-983168	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:FNop0ozErv05khKc5si7nNH/Hww9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:62E1C6A1AC90276E|rigid:5Y2SlNeRNSeF0jjuQMoetz0JIy0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q9UPQ4	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-2130401|uniprotkb:Q86XQ0|uniprotkb:Q8WVA4|ensembl:ENSP00000301924	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:tri35_human(display_long)|uniprotkb:TRIM35(gene name)|psi-mi:TRIM35(display_short)|uniprotkb:HLS5(gene name synonym)|uniprotkb:KIAA1098(gene name synonym)|uniprotkb:Hemopoietic lineage switch protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341151|imex:IM-11696-420	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_741983.2|ensembl:ENSG00000104228(gene)|ensembl:ENST00000305364(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR043136|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:VlC2XEURqN7nMIfIns2E0QVsL7k9606	intact-crc:9D2CA9220119C798|rigid:n0w7SJIgdevCXlOi9A3xa1m9Jnk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60291	uniprotkb:P51668	intact:EBI-2129851|uniprotkb:A4URL3|uniprotkb:A4URL4|uniprotkb:Q86W76|intact:EBI-28986785|ensembl:ENSP00000382487	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:mgrn1_human(display_long)|uniprotkb:MGRN1(gene name)|psi-mi:MGRN1(display_short)|uniprotkb:KIAA0544(gene name synonym)|uniprotkb:RNF156(gene name synonym)|uniprotkb:Mahogunin RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 156(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MGRN1(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341154|imex:IM-11696-421	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001135761.2|refseq:NP_001135762.1|refseq:NP_001135763.2|refseq:NP_056061.1|ensembl:ENST00000262370|ensembl:ENSP00000262370|ensembl:ENSP00000382487|ensembl:ENST00000415496|ensembl:ENSP00000393311|ensembl:ENST00000586183|ensembl:ENSP00000465860|ensembl:ENST00000588994|ensembl:ENSP00000468819|refseq:XP_005255277.1|refseq:XP_005255278.1|ensembl:ENSG00000102858(gene)|ensembl:ENST00000399577(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:UuLoCnlkpTBs/rmGgpQvgiMNuNE9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:A7A6DB42023E6B67|rigid:IfzJOKD5hukXakrEervXBvy4b5Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y577	uniprotkb:P51668	intact:EBI-743894|uniprotkb:B4DVJ2|uniprotkb:Q5VST8|ensembl:ENSP00000295033|ensembl:ENSP00000355658|ensembl:ENSP00000355659|ensembl:ENSP00000493891|ensembl:ENSP00000495842|ensembl:ENSP00000496098	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:tri17_human(display_long)|uniprotkb:Testis RING finger protein(gene name synonym)|uniprotkb:RING finger protein 16(gene name synonym)|uniprotkb:TRIM17(gene name)|psi-mi:TRIM17(display_short)|uniprotkb:RBCC(gene name synonym)|uniprotkb:RNF16(gene name synonym)|uniprotkb:TERF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 17(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM17(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341160|imex:IM-11696-159	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162931(gene)|ensembl:ENSG00000285344(gene)|refseq:NP_001020111.1|refseq:NP_001128327.1|refseq:NP_057186.1|refseq:XP_011542511.1|refseq:XP_011542512.1|refseq:XP_006711842.1|ensembl:ENST00000295033(transcript)|ensembl:ENST00000366697(transcript)|ensembl:ENST00000366698(transcript)|ensembl:ENST00000645562(transcript)|ensembl:ENST00000645958(transcript)|ensembl:ENST00000647385(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045087"(innate immune response)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032918|interpro:IPR035687|interpro:IPR043136|reactome:R-HSA-877300	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pXiCDkeNMtq9icQduH4MSCM6vSQ9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:3AB08B2BDEF6DAF9|rigid:e6BPvsJNPQII0I4YlvBE6hr+u2Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVW2	uniprotkb:P51668	intact:EBI-1996544|uniprotkb:Q9Y598|uniprotkb:Q96D38|uniprotkb:D3DTE0|uniprotkb:B2RBQ1|ensembl:ENSP00000253571|ensembl:ENSP00000328059	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:rnf12_human(display_long)|uniprotkb:RLIM(gene name)|psi-mi:RLIM(display_short)|uniprotkb:RNF12(gene name synonym)|uniprotkb:RING finger protein 12(gene name synonym)|uniprotkb:LIM domain-interacting RING finger protein(gene name synonym)|uniprotkb:RING finger LIM domain-binding protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-43(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RLIM(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341163|imex:IM-11696-160	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057204.2|refseq:NP_899196.1|ensembl:ENSG00000131263(gene)|ensembl:ENST00000332687(transcript)|ensembl:ENST00000349225(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060816"(random inactivation of X chromosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900095"(regulation of dosage compensation by inactivation of X chromosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NVW2|rcsb pdb:6W7Z|rcsb pdb:6W9A|rcsb pdb:6W9D|reactome:R-HSA-983168	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jEHiOt7hjZc5HU6E/XQGE7zdZbw9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:A0C2B899E47902F9|rigid:7xkerD2vtgRszHyuLhyONgiF6D0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q9C040	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341157|imex:IM-11696-422	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	intact-crc:2FE998A4E755810E|rigid:Dbt4C5m7YnToswIfCyTH00W04ik	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q6PCD5	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-2129159|uniprotkb:Q9H9Q3|uniprotkb:Q9NVT4|uniprotkb:Q5XKR3|uniprotkb:A8K585|uniprotkb:B2RE35|uniprotkb:D3DUJ8|ensembl:ENSP00000354361|ensembl:ENSP00000460049	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:rfwd3_human(display_long)|uniprotkb:RFWD3(gene name)|psi-mi:RFWD3(display_short)|uniprotkb:RING finger and WD repeat domain-containing protein 3(gene name synonym)|uniprotkb:RNF201(gene name synonym)|uniprotkb:RING finger protein 201(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341169|imex:IM-11696-162	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:XP_011521493.1|refseq:NP_060594.3|refseq:XP_016878880.1|refseq:XP_005256078.1|refseq:XP_005256079.1|dip:DIP-52688N|ensembl:ENSG00000168411(gene)|ensembl:ENST00000361070(transcript)|ensembl:ENST00000571750(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031297"(replication fork processing)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037381|rcsb pdb:6CVZ	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:r7gkMbkS0GKPVn9riLPR34KFaKk9606	intact-crc:73EAC7B9448E603D|rigid:rBSAknJwqBEsfZHMfZrDND9Kwcc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q9NZS9	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-2130199|uniprotkb:A8K4Z9|uniprotkb:D3DUG8|uniprotkb:B4DUT0|ensembl:ENSP00000261658|ensembl:ENSP00000478190	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:bfar_human(display_long)|uniprotkb:BFAR(gene name)|psi-mi:BFAR(display_short)|uniprotkb:BAR(gene name synonym)|uniprotkb:RNF47(gene name synonym)|uniprotkb:RING finger protein 47(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341166|imex:IM-11696-161	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_057645.1|refseq:XP_005255407.1|ensembl:ENSG00000103429(gene)|ensembl:ENSG00000275618(gene)|ensembl:ENST00000261658(transcript)|ensembl:ENST00000619034(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017907	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:XDPFsRmdbch1NXffLOcE0lVrtRo9606	intact-crc:1A45DB10200BB3BD|rigid:6mLQ7z8wIj2v1zczZVcdnHOxZiw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q6Q0C0	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-307556|uniprotkb:Q9H073|ensembl:ENSP00000318944	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:traf7_human(display_long)|uniprotkb:TRAF7(gene name)|psi-mi:TRAF7(display_short)|uniprotkb:TNF receptor-associated factor 7(gene name synonym)|uniprotkb:RING finger and WD repeat-containing protein 1(gene name synonym)|uniprotkb:RING finger protein 119(gene name synonym)|uniprotkb:RFWD1(gene name synonym)|uniprotkb:RNF119(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341175|imex:IM-11696-164	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_115647.2|ensembl:ENSG00000131653(gene)|ensembl:ENST00000326181(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017907|interpro:IPR019775|interpro:IPR020472|interpro:IPR027370|interpro:IPR036322|mint:Q6Q0C0|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:46dtsS1OairncB0fnINSW1aY2789606	intact-crc:AB0D4F7AC9079862|rigid:hyAnvOuzHCN3gQ4jEZQ/ag1xE3w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EP1	uniprotkb:P51668	intact:EBI-718923|uniprotkb:A6NEN5|uniprotkb:Q96SL3|uniprotkb:Q9NRT4|uniprotkb:Q9NT32|uniprotkb:Q9NVD5|uniprotkb:B4DZ77|uniprotkb:B4E2L6|ensembl:ENSP00000392395	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:chfr_human(display_long)|uniprotkb:Checkpoint with forkhead and RING finger domains protein(gene name synonym)|uniprotkb:RING finger protein 196(gene name synonym)|uniprotkb:CHFR(gene name)|psi-mi:CHFR(display_short)|uniprotkb:RNF196(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHFR(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341172|imex:IM-11696-163	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154816.1|refseq:NP_001154817.1|refseq:NP_001154818.1|refseq:NP_001154819.1|refseq:NP_060693.2|ensembl:ENSG00000072609(gene)|ensembl:ENST00000432561(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR019406|interpro:IPR040909|rcsb pdb:1LGP|rcsb pdb:1LGQ|rcsb pdb:2XOC|rcsb pdb:2XOY|rcsb pdb:2XOZ|rcsb pdb:2XP0|dip:DIP-40098N	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid://FU72n6rmuPAu+Fjm377S4nEjw9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:DB2A59155689F678|rigid:Zku70D/gHILRaIFuIGF0M6dm99c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q9BYV6	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-2341179|uniprotkb:Q96DV3|uniprotkb:Q9BYV5|uniprotkb:Q8IUD9|uniprotkb:Q8IUE4|uniprotkb:Q96DV2|uniprotkb:Q53XX3|uniprotkb:B3KRC0|uniprotkb:B3KRJ3|ensembl:ENSP00000323913	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:tri55_human(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341178|imex:IM-11696-165	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:XP_011515915.1|refseq:XP_011515916.1|refseq:XP_011515917.1|refseq:XP_011515918.1|refseq:NP_149047.2|refseq:NP_908973.1|refseq:NP_908974.1|refseq:NP_908975.1|ensembl:ENSG00000147573(gene)|ensembl:ENST00000315962(transcript)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0050904"(diapedesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1905517"(macrophage migration)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR033492|mint:Q9BYV6	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:MiXH7mPPLOjav9yf0/HL7neg3yI9606	intact-crc:854BD5C4CF9447B0|rigid:JXieuZLdXmiCUTUnGyi8Kr8b8cc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q9C035	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-924214|uniprotkb:Q2MLV4|uniprotkb:Q2MLV8|uniprotkb:Q2MLV9|uniprotkb:Q2MLW1|uniprotkb:Q2MLW3|uniprotkb:Q2MLW4|uniprotkb:A6NGQ1|uniprotkb:Q2MLW6|uniprotkb:Q2MLW7|uniprotkb:Q2MLX1|uniprotkb:Q2MLX2|uniprotkb:Q2MLX3|uniprotkb:Q2MLX5|uniprotkb:Q2MLY3|uniprotkb:Q2MLY4|uniprotkb:Q2V6Q6|uniprotkb:Q6GX26|uniprotkb:Q8WU46|uniprotkb:Q96SR5|uniprotkb:Q9C031|uniprotkb:Q9C032|uniprotkb:Q9C033|uniprotkb:Q9C034|uniprotkb:A8WFA8|uniprotkb:D3DQS8|uniprotkb:D3DQS9|uniprotkb:G3GJY1|ensembl:ENSP00000369373|ensembl:ENSP00000507420	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:trim5_human(display_long)|uniprotkb:TRIM5(gene name)|psi-mi:TRIM5(display_short)|uniprotkb:RNF88(gene name synonym)|uniprotkb:RING finger protein 88(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341191|imex:IM-11696-166	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_149023.2|refseq:NP_149083.2|refseq:NP_149084.2|refseq:XP_011518729.1|refseq:XP_005253240.1|refseq:XP_005253241.1|ensembl:ENSG00000132256(gene)|ensembl:ENST00000380034(transcript)|ensembl:ENST00000684655(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031664"(regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR043136|rcsb pdb:2ECV|rcsb pdb:2YRG|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:t0YqhaJC8oQcwot7oks1LgMxdNc9606	intact-crc:EDDBEED6D492D378|rigid:xdWP0WO5JV5OLnLXj9JC7k0aXfI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q6UWE0	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-720984|uniprotkb:Q5VVV0|uniprotkb:Q8NB40|uniprotkb:Q96GT5|uniprotkb:Q96MX5|uniprotkb:Q96MZ7|ensembl:ENSP00000300417|ensembl:ENSP00000322937|ensembl:ENSP00000362419|ensembl:ENSP00000502167	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:lrsm1_human(display_long)|uniprotkb:Leucine-rich repeat and sterile alpha motif-containing protein 1(gene name synonym)|uniprotkb:Tsg101-associated ligase(gene name synonym)|uniprotkb:LRSAM1(gene name)|psi-mi:LRSAM1(display_short)|uniprotkb:TAL(gene name synonym)|uniprotkb:UNQ6496/PRO21356(orf name)|uniprotkb:RING-type E3 ubiquitin transferase LRSAM1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341194|imex:IM-11696-167	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_001005373.1|refseq:NP_001005374.1|refseq:NP_001177652.1|refseq:NP_612370.3|refseq:XP_016870772.1|ensembl:ENSG00000148356(gene)|ensembl:ENST00000300417(transcript)|ensembl:ENST00000323301(transcript)|ensembl:ENST00000373322(transcript)|ensembl:ENST00000675448(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0046755"(viral budding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032675|mint:Q6UWE0|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:qkwPqOsfNjZBB2Xp6YAA9FbEZxM9606	intact-crc:E7CB265AF1AF8552|rigid:z1YjbUHV9OE4TX3SyLSjqs3TATo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q96P09	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-2341055|uniprotkb:Q96RW5|uniprotkb:Q6IPY1	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:birc8_human(display_long)|uniprotkb:BIRC8(gene name)|psi-mi:BIRC8(display_short)|uniprotkb:ILP2(gene name synonym)|uniprotkb:Inhibitor of apoptosis-like protein 2(gene name synonym)|uniprotkb:Testis-specific inhibitor of apoptosis(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341197|imex:IM-11696-168	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	interpro:IPR042579|refseq:NP_203127.3|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:1XB0|rcsb pdb:1XB1|interpro:IPR011029(DEATH-like)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:dNa54zbu4SMSRJ8FXGBLuqGJ0qo9606	intact-crc:55640FA56B43930B|rigid:5GqMT1j7olX6OL3j1eQg543+wPw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H0F5	uniprotkb:P51668	intact:EBI-2341200|uniprotkb:Q8N0Y0|uniprotkb:A6PVP9|uniprotkb:B1AM82|uniprotkb:Q7LB33|ensembl:ENSP00000259605|uniprotkb:B1AM81|uniprotkb:B3KSG4|uniprotkb:E7EVL3|uniprotkb:Q9H748	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:rnf38_human(display_long)|uniprotkb:RING finger protein 38(gene name synonym)|uniprotkb:RNF38(gene name)|psi-mi:RNF38(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF38(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341206|imex:IM-11696-169	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011516014.1|refseq:XP_011516015.1|refseq:XP_006716784.1|refseq:NP_073618.3|refseq:NP_919309.1|refseq:NP_919310.1|refseq:NP_919311.1|refseq:NP_919313.1|ensembl:ENSG00000137075(gene)|ensembl:ENST00000259605(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008584"(male gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|go:"GO:0036126"(sperm flagellum)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9H0F5|rcsb pdb:1X4J|rcsb pdb:4V3K|rcsb pdb:4V3L|ensembl:ENSP00000259605|ensembl:ENST00000350199|ensembl:ENSP00000343947|ensembl:ENST00000353739|ensembl:ENSP00000335239|ensembl:ENST00000357058|ensembl:ENSP00000349566|ensembl:ENST00000377877|ensembl:ENSP00000367109|ensembl:ENST00000377885|ensembl:ENSP00000367117|ensembl:ENST00000611646|ensembl:ENSP00000483536|refseq:XP_005251423.1|refseq:XP_005251424.1|refseq:XP_005251425.1|refseq:XP_016869784.1	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:leJgsTFAtsRhHPh44pbrpk1wkDo9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:4E5B6D61455BD39A|rigid:g8I1prt7O72olMn2tm/JONvCOQo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:P78317	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-2340927|uniprotkb:Q49AR8|uniprotkb:B2R6D6|uniprotkb:D6RF58|intact:EBI-28970119|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:rnf4_human(display_long)|uniprotkb:SNURF(gene name synonym)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:RNF4(gene name)|psi-mi:RNF4(display_short)|uniprotkb:RES4-26(orf name)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341212|imex:IM-11696-171	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_001171938.1|refseq:NP_001171939.1|refseq:NP_002929.1|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503|ensembl:ENST00000511859|ensembl:ENSP00000426615|ensembl:ENST00000541204|ensembl:ENSP00000446369|ensembl:ENSG00000063978(gene)|ensembl:ENST00000314289(transcript)|ensembl:ENST00000506706(transcript)|ensembl:ENST00000511600(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|go:"GO:1990752"(microtubule end)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|mint:P78317|rcsb pdb:2EA6|rcsb pdb:2XEU|rcsb pdb:4PPE|reactome:R-HSA-5693607|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:Yhu2iAaNQYcfGdYohDPBdhMFEpc9606	intact-crc:D6A5352EC5E6E1C3|rigid:FtApFJafGnLCoey9wi9YQ6kVLVc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKV5	uniprotkb:P62837	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341209|imex:IM-11696-170	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:2BC79D32312F0E9C|rigid:gaErtrfpsZUy5cR2cEs6umbML8w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q8IUQ4	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-747107|uniprotkb:O43269|uniprotkb:Q49A58|uniprotkb:A0FKF3|uniprotkb:Q92880|ensembl:ENSP00000369343|ensembl:ENSP00000378214|ensembl:ENSP00000456421	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:siah1_human(display_long)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341215|imex:IM-11696-172	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:XP_006721309.1|refseq:NP_001006611.1|refseq:NP_003022.3|refseq:XP_011521581.1|ensembl:ENST00000380006(transcript)|ensembl:ENST00000394725(transcript)|ensembl:ENST00000568007(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|mint:Q8IUQ4|rcsb pdb:2A25|rcsb pdb:4C9Z|rcsb pdb:4CA1|rcsb pdb:4I7B|rcsb pdb:4I7C|rcsb pdb:4I7D|rcsb pdb:4X3G|rcsb pdb:5WZZ|reactome:R-HSA-373752|reactome:R-HSA-977225|reactome:R-HSA-983168|ensembl:ENSG00000196470(gene)|dip:DIP-35684N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:O6+z1g9K1ij87Xgo5/Ykl5Q3vUQ9606	intact-crc:5380C7FEAAD72E74|rigid:7a0FXVgeC15b+FazZ7+8QTUdBQ4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y4K3	uniprotkb:P62837	intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|ensembl:ENSP00000337853|ensembl:ENSP00000433623|uniprotkb:D3DR16	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341218|imex:IM-11696-173	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004611.1|refseq:NP_665802.1|ensembl:ENSG00000175104(gene)|ensembl:ENST00000348124(transcript)|ensembl:ENST00000526995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|go:"GO:0070534"(protein K63-linked ubiquitination)|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|go:"GO:0070555"(response to interleukin-1)|rcsb pdb:7L3L|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|go:"GO:0071222"(cellular response to lipopolysaccharide)|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-975871|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|dip:DIP-27515N	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:DF508E0E707156C0|rigid:3h2mtmZQ+C9QPvD+GhtKkr1zcgk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBF6	uniprotkb:P62837	intact:EBI-398632|uniprotkb:Q9BXN8|uniprotkb:Q9Y5M7|uniprotkb:A8MTB5|uniprotkb:A8K1H9|uniprotkb:D3DNF7|uniprotkb:D3DNF8|uniprotkb:C9JYL3|ensembl:ENSP00000273480	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:rbx2_human(display_long)|uniprotkb:RNF7(gene name)|psi-mi:RNF7(display_short)|uniprotkb:RBX2(gene name synonym)|uniprotkb:ROC2(gene name synonym)|uniprotkb:SAG(gene name synonym)|uniprotkb:RING finger protein 7(gene name synonym)|uniprotkb:Regulator of cullins 2(gene name synonym)|uniprotkb:CKII beta-binding protein 1(gene name synonym)|uniprotkb:Sensitive to apoptosis gene protein(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341227|imex:IM-11696-425	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055060.1|refseq:NP_899060.1|refseq:NP_001188299.1|ensembl:ENSG00000114125(gene)|ensembl:ENST00000273480(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045116"(protein neddylation)|go:"GO:0051775"(response to redox state)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|rcsb pdb:2ECL|reactome:R-HSA-8951664|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:FNop0ozErv05khKc5si7nNH/Hww9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:CDDD2AB56F27B75F|rigid:8FiIsjjqifTxT05ncVENCNPonFQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q14258	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-2341129|intact:EBI-28973868|ensembl:ENSP00000323889|ensembl:ENSP00000445961	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:tri25_human(display_long)|uniprotkb:TRIM25(gene name)|psi-mi:TRIM25(display_short)|uniprotkb:EFP(gene name synonym)|uniprotkb:RNF147(gene name synonym)|uniprotkb:ZNF147(gene name synonym)|uniprotkb:Zinc finger protein 147(gene name synonym)|uniprotkb:Estrogen-responsive finger protein(gene name synonym)|uniprotkb:RING finger protein 147(gene name synonym)|uniprotkb:Ubiquitin/ISG15-conjugating enzyme TRIM25(gene name synonym)|uniprotkb:Tripartite motif-containing protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM25(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341221|imex:IM-11696-423	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	ensembl:ENSP00000323889|ensembl:ENSP00000445961|refseq:NP_005073.2|ensembl:ENSG00000121060(gene)|ensembl:ENST00000316881(transcript)|ensembl:ENST00000537230(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016604"(nuclear body)|go:"GO:0016874"(ligase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033280"(response to vitamin D)|go:"GO:0039552"(RIG-I binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043627"(response to estrogen)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|go:"GO:1902187"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042753|interpro:IPR043136|mint:Q14258|rcsb pdb:4CFG|rcsb pdb:4LTB|rcsb pdb:5EYA|rcsb pdb:5FER|rcsb pdb:5NT1|rcsb pdb:5NT2|rcsb pdb:6FLM|rcsb pdb:6FLN|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-5689896|reactome:R-HSA-877300|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:NhFfC0IxHvxPIt2YnKCPsPKuiQA9606	intact-crc:43E4318206EA06A8|rigid:cbSIPwxCOnHoxuJHsnRtbQcszyE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12899	uniprotkb:P62837	intact:EBI-2341136|intact:EBI-2802887|uniprotkb:A6NG96|uniprotkb:Q5SRL2|ensembl:ENSP00000331131|ensembl:ENSP00000373102|ensembl:ENSP00000379806|ensembl:ENSP00000389203|ensembl:ENSP00000390258|ensembl:ENSP00000391879|ensembl:ENSP00000392805|ensembl:ENSP00000393011|ensembl:ENSP00000394371|ensembl:ENSP00000394421|ensembl:ENSP00000395491|ensembl:ENSP00000396188|ensembl:ENSP00000398545|ensembl:ENSP00000402395|ensembl:ENSP00000406707|ensembl:ENSP00000407294|ensembl:ENSP00000407876|ensembl:ENSP00000408233|ensembl:ENSP00000409182|ensembl:ENSP00000410446|ensembl:ENSP00000414248|ensembl:ENSP00000415328|ensembl:ENSP00000415755|ensembl:ENSP00000416737	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:tri26_human(display_long)|uniprotkb:TRIM26(gene name)|psi-mi:TRIM26(display_short)|uniprotkb:RNF95(gene name synonym)|uniprotkb:ZNF173(gene name synonym)|uniprotkb:Zinc finger protein 173(gene name synonym)|uniprotkb:Acid finger protein(gene name synonym)|uniprotkb:RING finger protein 95(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341224|imex:IM-11696-424	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006715243.1|refseq:NP_001229712.1|refseq:NP_003440.1|refseq:XP_005249431.1|refseq:XP_005249432.1|refseq:XP_005249433.1|refseq:XP_005249434.1|refseq:XP_005249435.1|dip:DIP-52853N|ensembl:ENSG00000137313(gene)|ensembl:ENSG00000226060(gene)|ensembl:ENSG00000228881(gene)|ensembl:ENSG00000230230(gene)|ensembl:ENSG00000231002(gene)|ensembl:ENSG00000231641(gene)|ensembl:ENSG00000234046(gene)|ensembl:ENSG00000234127(gene)|ensembl:ENST00000327357(transcript)|ensembl:ENST00000383607(transcript)|ensembl:ENST00000396558(transcript)|ensembl:ENST00000415923(transcript)|ensembl:ENST00000422349(transcript)|ensembl:ENST00000425523(transcript)|ensembl:ENST00000425831(transcript)|ensembl:ENST00000427535(transcript)|ensembl:ENST00000428486(transcript)|ensembl:ENST00000432326(transcript)|ensembl:ENST00000433314(transcript)|ensembl:ENST00000436219(transcript)|ensembl:ENST00000437089(transcript)|ensembl:ENST00000438384(transcript)|ensembl:ENST00000438908(transcript)|ensembl:ENST00000439094(transcript)|ensembl:ENST00000445259(transcript)|ensembl:ENST00000447711(transcript)|ensembl:ENST00000450392(transcript)|ensembl:ENST00000453195(transcript)|ensembl:ENST00000454678(transcript)|ensembl:ENST00000455000(transcript)|ensembl:ENST00000456093(transcript)|ensembl:ENST00000456770(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR043136|mint:Q12899|reactome:R-HSA-877300	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:GPu3YgJ3xR1pN/MM9IKU3unCj1A9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:6D6444B5FF4D6825|rigid:Wb9y1ZnHcD00m9RlZ0W5a7UHTJg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q9UPQ4	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-2130401|uniprotkb:Q86XQ0|uniprotkb:Q8WVA4|ensembl:ENSP00000301924	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:tri35_human(display_long)|uniprotkb:TRIM35(gene name)|psi-mi:TRIM35(display_short)|uniprotkb:HLS5(gene name synonym)|uniprotkb:KIAA1098(gene name synonym)|uniprotkb:Hemopoietic lineage switch protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341236|imex:IM-11696-428	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_741983.2|ensembl:ENSG00000104228(gene)|ensembl:ENST00000305364(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR043136|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:VlC2XEURqN7nMIfIns2E0QVsL7k9606	intact-crc:32104536C2AE57A9|rigid:zTGReO2y7xi06ayiDcbBDWEYzF4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:O95376	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-711158|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9|ensembl:ENSP00000348769|ensembl:ENSP00000403222	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341230|imex:IM-11696-426	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|ensembl:ENSG00000177479(gene)|ensembl:ENST00000356401(transcript)|ensembl:ENST00000449376(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|refseq:XP_016861020.1|refseq:XP_016861021.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	intact-crc:C261DF4264676513|rigid:E+N36hwIHXV9vNRxBev7TAV0uMY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q9BZY9	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-747544|uniprotkb:Q53H52|uniprotkb:Q5RI37|uniprotkb:Q5SRJ7|uniprotkb:Q5SRJ8|uniprotkb:Q5SS28|uniprotkb:Q96AK4|uniprotkb:Q96AP8|uniprotkb:Q99579|uniprotkb:Q9BZY8|uniprotkb:A6NLX6|uniprotkb:A9R9Q4|ensembl:ENSP00000350182|ensembl:ENSP00000365924|ensembl:ENSP00000390551|ensembl:ENSP00000391685|ensembl:ENSP00000398677|ensembl:ENSP00000409501	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:tri31_human(display_long)|uniprotkb:TRIM31(gene name)|psi-mi:TRIM31(display_short)|uniprotkb:C6orf13(gene name synonym)|uniprotkb:RNF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 31(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM31(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341233|imex:IM-11696-427	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_008959.3|ensembl:ENSG00000137397(gene)|ensembl:ENSG00000204616(gene)|ensembl:ENSG00000223531(gene)|ensembl:ENSG00000224168(gene)|ensembl:ENSG00000225130(gene)|ensembl:ENSG00000233573(gene)|ensembl:ENST00000357569(transcript)|ensembl:ENST00000376734(transcript)|ensembl:ENST00000433864(transcript)|ensembl:ENST00000445679(transcript)|ensembl:ENST00000449412(transcript)|ensembl:ENST00000453266(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR020457|rcsb pdb:2YSJ|rcsb pdb:2YSL|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:f7qMSpsjq1gDv+rl2o2BWpXhvKw9606	intact-crc:A8CD208E64E8C9E9|rigid:z+Fnwavfbn/riOSiSQTYKZiOTEI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:O60291	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-2129851|uniprotkb:A4URL3|uniprotkb:A4URL4|uniprotkb:Q86W76|intact:EBI-28986785|ensembl:ENSP00000382487	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:mgrn1_human(display_long)|uniprotkb:MGRN1(gene name)|psi-mi:MGRN1(display_short)|uniprotkb:KIAA0544(gene name synonym)|uniprotkb:RNF156(gene name synonym)|uniprotkb:Mahogunin RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 156(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MGRN1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341239|imex:IM-11696-429	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_001135761.2|refseq:NP_001135762.1|refseq:NP_001135763.2|refseq:NP_056061.1|ensembl:ENST00000262370|ensembl:ENSP00000262370|ensembl:ENSP00000382487|ensembl:ENST00000415496|ensembl:ENSP00000393311|ensembl:ENST00000586183|ensembl:ENSP00000465860|ensembl:ENST00000588994|ensembl:ENSP00000468819|refseq:XP_005255277.1|refseq:XP_005255278.1|ensembl:ENSG00000102858(gene)|ensembl:ENST00000399577(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:UuLoCnlkpTBs/rmGgpQvgiMNuNE9606	intact-crc:6DE8970DA3BFD616|rigid:o5s+Z/IcMfD9daZ1XFUQCDRLJUc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q9C040	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341242|imex:IM-11696-430	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	intact-crc:80D574B024E2113F|rigid:NJTzVz5UDVVtGhrXTPgYjTa5KsI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NZS9	uniprotkb:P62837	intact:EBI-2130199|uniprotkb:A8K4Z9|uniprotkb:D3DUG8|uniprotkb:B4DUT0|ensembl:ENSP00000261658|ensembl:ENSP00000478190	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:bfar_human(display_long)|uniprotkb:BFAR(gene name)|psi-mi:BFAR(display_short)|uniprotkb:BAR(gene name synonym)|uniprotkb:RNF47(gene name synonym)|uniprotkb:RING finger protein 47(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341251|imex:IM-11696-433	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057645.1|refseq:XP_005255407.1|ensembl:ENSG00000103429(gene)|ensembl:ENSG00000275618(gene)|ensembl:ENST00000261658(transcript)|ensembl:ENST00000619034(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017907	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:XDPFsRmdbch1NXffLOcE0lVrtRo9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:B5793704E3BC238C|rigid:EsuNfoZ2HiFftkJSKhVoBhM71Fo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q9Y577	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-743894|uniprotkb:B4DVJ2|uniprotkb:Q5VST8|ensembl:ENSP00000295033|ensembl:ENSP00000355658|ensembl:ENSP00000355659|ensembl:ENSP00000493891|ensembl:ENSP00000495842|ensembl:ENSP00000496098	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:tri17_human(display_long)|uniprotkb:Testis RING finger protein(gene name synonym)|uniprotkb:RING finger protein 16(gene name synonym)|uniprotkb:TRIM17(gene name)|psi-mi:TRIM17(display_short)|uniprotkb:RBCC(gene name synonym)|uniprotkb:RNF16(gene name synonym)|uniprotkb:TERF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 17(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM17(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341245|imex:IM-11696-431	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	ensembl:ENSG00000162931(gene)|ensembl:ENSG00000285344(gene)|refseq:NP_001020111.1|refseq:NP_001128327.1|refseq:NP_057186.1|refseq:XP_011542511.1|refseq:XP_011542512.1|refseq:XP_006711842.1|ensembl:ENST00000295033(transcript)|ensembl:ENST00000366697(transcript)|ensembl:ENST00000366698(transcript)|ensembl:ENST00000645562(transcript)|ensembl:ENST00000645958(transcript)|ensembl:ENST00000647385(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045087"(innate immune response)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032918|interpro:IPR035687|interpro:IPR043136|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:pXiCDkeNMtq9icQduH4MSCM6vSQ9606	intact-crc:958C673F1D414AC8|rigid:rCzX1t+nJtRdAwwyouHZx0xUarI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q9NVW2	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-1996544|uniprotkb:Q9Y598|uniprotkb:Q96D38|uniprotkb:D3DTE0|uniprotkb:B2RBQ1|ensembl:ENSP00000253571|ensembl:ENSP00000328059	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:rnf12_human(display_long)|uniprotkb:RLIM(gene name)|psi-mi:RLIM(display_short)|uniprotkb:RNF12(gene name synonym)|uniprotkb:RING finger protein 12(gene name synonym)|uniprotkb:LIM domain-interacting RING finger protein(gene name synonym)|uniprotkb:RING finger LIM domain-binding protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-43(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RLIM(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341248|imex:IM-11696-432	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_057204.2|refseq:NP_899196.1|ensembl:ENSG00000131263(gene)|ensembl:ENST00000332687(transcript)|ensembl:ENST00000349225(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060816"(random inactivation of X chromosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900095"(regulation of dosage compensation by inactivation of X chromosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NVW2|rcsb pdb:6W7Z|rcsb pdb:6W9A|rcsb pdb:6W9D|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:jEHiOt7hjZc5HU6E/XQGE7zdZbw9606	intact-crc:0FFE548D27CE92C8|rigid:/bmg20oyRJtWj3GM8GBNxukH8vI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q6Q0C0	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-307556|uniprotkb:Q9H073|ensembl:ENSP00000318944	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:traf7_human(display_long)|uniprotkb:TRAF7(gene name)|psi-mi:TRAF7(display_short)|uniprotkb:TNF receptor-associated factor 7(gene name synonym)|uniprotkb:RING finger and WD repeat-containing protein 1(gene name synonym)|uniprotkb:RING finger protein 119(gene name synonym)|uniprotkb:RFWD1(gene name synonym)|uniprotkb:RNF119(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341260|imex:IM-11696-436	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_115647.2|ensembl:ENSG00000131653(gene)|ensembl:ENST00000326181(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017907|interpro:IPR019775|interpro:IPR020472|interpro:IPR027370|interpro:IPR036322|mint:Q6Q0C0|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:46dtsS1OairncB0fnINSW1aY2789606	intact-crc:0431A36E0AB00853|rigid:1Kua/YoXZy94v+4GLP32ljxGxZ8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q8WVD3	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-749039|uniprotkb:Q9H8K2|uniprotkb:Q9UF87|uniprotkb:Q9UKI6|uniprotkb:B2RE17|ensembl:ENSP00000261593	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:rn138_human(display_long)|uniprotkb:RING finger protein 138(gene name synonym)|uniprotkb:Nemo-like kinase-associated RING finger protein(gene name synonym)|uniprotkb:RNF138(gene name)|psi-mi:RNF138(display_short)|uniprotkb:NARF(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF138(gene name synonym)|uniprotkb:HSD-4(orf name)|uniprotkb:HSD4(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341254|imex:IM-11696-434	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_057355.2|refseq:NP_937761.1|refseq:NP_001178253.2|refseq:XP_005258343.1|ensembl:ENSG00000134758(gene)|ensembl:ENST00000261593(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034734|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:HhGscRenFoqXTiZxHR62E4wcIo09606	intact-crc:FDED13D1E975F52D|rigid:d1lYeoWA8W6jBRIXj/xdTuKnX5o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EP1	uniprotkb:P62837	intact:EBI-718923|uniprotkb:A6NEN5|uniprotkb:Q96SL3|uniprotkb:Q9NRT4|uniprotkb:Q9NT32|uniprotkb:Q9NVD5|uniprotkb:B4DZ77|uniprotkb:B4E2L6|ensembl:ENSP00000392395	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:chfr_human(display_long)|uniprotkb:Checkpoint with forkhead and RING finger domains protein(gene name synonym)|uniprotkb:RING finger protein 196(gene name synonym)|uniprotkb:CHFR(gene name)|psi-mi:CHFR(display_short)|uniprotkb:RNF196(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHFR(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341257|imex:IM-11696-435	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154816.1|refseq:NP_001154817.1|refseq:NP_001154818.1|refseq:NP_001154819.1|refseq:NP_060693.2|ensembl:ENSG00000072609(gene)|ensembl:ENST00000432561(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR019406|interpro:IPR040909|rcsb pdb:1LGP|rcsb pdb:1LGQ|rcsb pdb:2XOC|rcsb pdb:2XOY|rcsb pdb:2XOZ|rcsb pdb:2XP0|dip:DIP-40098N	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid://FU72n6rmuPAu+Fjm377S4nEjw9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:7416B501953E6649|rigid:OP2wbUI7ITjhKjowQuuXeg06TfI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BYV6	uniprotkb:P62837	intact:EBI-2341179|uniprotkb:Q96DV3|uniprotkb:Q9BYV5|uniprotkb:Q8IUD9|uniprotkb:Q8IUE4|uniprotkb:Q96DV2|uniprotkb:Q53XX3|uniprotkb:B3KRC0|uniprotkb:B3KRJ3|ensembl:ENSP00000323913	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:tri55_human(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341263|imex:IM-11696-437	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011515915.1|refseq:XP_011515916.1|refseq:XP_011515917.1|refseq:XP_011515918.1|refseq:NP_149047.2|refseq:NP_908973.1|refseq:NP_908974.1|refseq:NP_908975.1|ensembl:ENSG00000147573(gene)|ensembl:ENST00000315962(transcript)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0050904"(diapedesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1905517"(macrophage migration)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR033492|mint:Q9BYV6	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:MiXH7mPPLOjav9yf0/HL7neg3yI9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:2A7739D00C23D781|rigid:6AbAv+YKKfC6IJNLTgo4U+fFTAk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	intact:EBI-2341266	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	-	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:a6nlp3_human(display_short)|psi-mi:EBI-2341266(display_long)|uniprotkb:TRIM5(gene name)|psi-mi:TRIM5(display_short)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341270|imex:IM-11696-438	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	uniprotkb:A6NLP3(uniprot-removed-ac)	psi-mi:"MI:0469"(intact)	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:72k0V9EE7ZSLFBtLnrw5+ESLfKk9606	intact-crc:15CCDB00CB5DA763|rigid:2+lNspwSOOdA7x1iT6jv4TXQ3hM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q96DX4	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-2341274|uniprotkb:Q8ND53|uniprotkb:Q6UX21|ensembl:ENSP00000377942|ensembl:ENSP00000443176	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:rspry_human(display_long)|uniprotkb:RSPRY1(gene name)|psi-mi:RSPRY1(display_short)|uniprotkb:KIAA1972(gene name synonym)|uniprotkb:UNQ328/PRO444(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341273|imex:IM-11696-439	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_001292092.1|refseq:NP_001292093.1|refseq:NP_001292111.1|refseq:NP_588609.1|refseq:XP_005256277.1|ensembl:ENSG00000159579(gene)|ensembl:ENST00000394420(transcript)|ensembl:ENST00000537866(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035774|interpro:IPR043136	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:WIh5Nn9L+KH2Zw9m3M+sFpMo2/M9606	intact-crc:D25F956C6DADFB14|rigid:REM3siAdU1Pw8rQlUfWzAigY3YM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6UWE0	uniprotkb:P62837	intact:EBI-720984|uniprotkb:Q5VVV0|uniprotkb:Q8NB40|uniprotkb:Q96GT5|uniprotkb:Q96MX5|uniprotkb:Q96MZ7|ensembl:ENSP00000300417|ensembl:ENSP00000322937|ensembl:ENSP00000362419|ensembl:ENSP00000502167	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:lrsm1_human(display_long)|uniprotkb:Leucine-rich repeat and sterile alpha motif-containing protein 1(gene name synonym)|uniprotkb:Tsg101-associated ligase(gene name synonym)|uniprotkb:LRSAM1(gene name)|psi-mi:LRSAM1(display_short)|uniprotkb:TAL(gene name synonym)|uniprotkb:UNQ6496/PRO21356(orf name)|uniprotkb:RING-type E3 ubiquitin transferase LRSAM1(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341282|imex:IM-11696-440	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005373.1|refseq:NP_001005374.1|refseq:NP_001177652.1|refseq:NP_612370.3|refseq:XP_016870772.1|ensembl:ENSG00000148356(gene)|ensembl:ENST00000300417(transcript)|ensembl:ENST00000323301(transcript)|ensembl:ENST00000373322(transcript)|ensembl:ENST00000675448(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0046755"(viral budding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032675|mint:Q6UWE0|reactome:R-HSA-983168	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:qkwPqOsfNjZBB2Xp6YAA9FbEZxM9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:48F7CA4E32181563|rigid:UAjL0R8T0wsXrYLsi25tWlRfY74	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62837	uniprotkb:Q9H0F5	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-2341200|uniprotkb:Q8N0Y0|uniprotkb:A6PVP9|uniprotkb:B1AM82|uniprotkb:Q7LB33|ensembl:ENSP00000259605|uniprotkb:B1AM81|uniprotkb:B3KSG4|uniprotkb:E7EVL3|uniprotkb:Q9H748	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:rnf38_human(display_long)|uniprotkb:RING finger protein 38(gene name synonym)|uniprotkb:RNF38(gene name)|psi-mi:RNF38(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF38(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341291|imex:IM-11696-443	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:XP_011516014.1|refseq:XP_011516015.1|refseq:XP_006716784.1|refseq:NP_073618.3|refseq:NP_919309.1|refseq:NP_919310.1|refseq:NP_919311.1|refseq:NP_919313.1|ensembl:ENSG00000137075(gene)|ensembl:ENST00000259605(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008584"(male gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|go:"GO:0036126"(sperm flagellum)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9H0F5|rcsb pdb:1X4J|rcsb pdb:4V3K|rcsb pdb:4V3L|ensembl:ENSP00000259605|ensembl:ENST00000350199|ensembl:ENSP00000343947|ensembl:ENST00000353739|ensembl:ENSP00000335239|ensembl:ENST00000357058|ensembl:ENSP00000349566|ensembl:ENST00000377877|ensembl:ENSP00000367109|ensembl:ENST00000377885|ensembl:ENSP00000367117|ensembl:ENST00000611646|ensembl:ENSP00000483536|refseq:XP_005251423.1|refseq:XP_005251424.1|refseq:XP_005251425.1|refseq:XP_016869784.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:leJgsTFAtsRhHPh44pbrpk1wkDo9606	intact-crc:E167817586EC43AB|rigid:GhWv65u5BWsHWDxP9r1PaKHm3SE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96P09	uniprotkb:P62837	intact:EBI-2341055|uniprotkb:Q96RW5|uniprotkb:Q6IPY1	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:birc8_human(display_long)|uniprotkb:BIRC8(gene name)|psi-mi:BIRC8(display_short)|uniprotkb:ILP2(gene name synonym)|uniprotkb:Inhibitor of apoptosis-like protein 2(gene name synonym)|uniprotkb:Testis-specific inhibitor of apoptosis(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341285|imex:IM-11696-441	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR042579|refseq:NP_203127.3|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:1XB0|rcsb pdb:1XB1|interpro:IPR011029(DEATH-like)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dNa54zbu4SMSRJ8FXGBLuqGJ0qo9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:FA58E3B1A8F4033A|rigid:/0omvzGhlRcKvU1t2pxELRywTUM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86UD3	uniprotkb:P62837	intact:EBI-2341065|uniprotkb:A8K264|uniprotkb:B9EJE7|ensembl:ENSP00000309141	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:marh3_human(display_long)|uniprotkb:MARCHF3(gene name)|psi-mi:MARCHF3(display_short)|uniprotkb:MARCH3(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 3(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein III(gene name synonym)|uniprotkb:RING finger protein 173(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF3(gene name synonym)|uniprotkb:RNF173(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341288|imex:IM-11696-442	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_848545.1|ensembl:ENSG00000173926(gene)|ensembl:ENST00000308660(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:uv/JcWUoL549NACFaOUs/oLdHuI9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:6AAC00442FD66067|rigid:1kSXSWxTyqNH9WcCBCoM5Cwla7Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P78317	uniprotkb:P61077	intact:EBI-2340927|uniprotkb:Q49AR8|uniprotkb:B2R6D6|uniprotkb:D6RF58|intact:EBI-28970119|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:rnf4_human(display_long)|uniprotkb:SNURF(gene name synonym)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:RNF4(gene name)|psi-mi:RNF4(display_short)|uniprotkb:RES4-26(orf name)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341300|imex:IM-11696-446	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171938.1|refseq:NP_001171939.1|refseq:NP_002929.1|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503|ensembl:ENST00000511859|ensembl:ENSP00000426615|ensembl:ENST00000541204|ensembl:ENSP00000446369|ensembl:ENSG00000063978(gene)|ensembl:ENST00000314289(transcript)|ensembl:ENST00000506706(transcript)|ensembl:ENST00000511600(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|go:"GO:1990752"(microtubule end)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|mint:P78317|rcsb pdb:2EA6|rcsb pdb:2XEU|rcsb pdb:4PPE|reactome:R-HSA-5693607|reactome:R-HSA-983168	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Yhu2iAaNQYcfGdYohDPBdhMFEpc9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:496C889B04C33AAF|rigid:eRd5oPqzSoj+jpp6jEB1DC9dTg8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q9UKV5	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341294|imex:IM-11696-444	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	intact-crc:5C67F3F9DD90069A|rigid:ggs6EK0N3nPhxL8lzWy+31KD80k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q06587	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341297|imex:IM-11696-445	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606	intact-crc:7F4FA827C0E2DC36|rigid:DD8MDcpj/cYSAfBMm2T8M9TefI0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IUQ4	uniprotkb:P61077	intact:EBI-747107|uniprotkb:O43269|uniprotkb:Q49A58|uniprotkb:A0FKF3|uniprotkb:Q92880|ensembl:ENSP00000369343|ensembl:ENSP00000378214|ensembl:ENSP00000456421	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:siah1_human(display_long)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341303|imex:IM-11696-447	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006721309.1|refseq:NP_001006611.1|refseq:NP_003022.3|refseq:XP_011521581.1|ensembl:ENST00000380006(transcript)|ensembl:ENST00000394725(transcript)|ensembl:ENST00000568007(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|mint:Q8IUQ4|rcsb pdb:2A25|rcsb pdb:4C9Z|rcsb pdb:4CA1|rcsb pdb:4I7B|rcsb pdb:4I7C|rcsb pdb:4I7D|rcsb pdb:4X3G|rcsb pdb:5WZZ|reactome:R-HSA-373752|reactome:R-HSA-977225|reactome:R-HSA-983168|ensembl:ENSG00000196470(gene)|dip:DIP-35684N	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:O6+z1g9K1ij87Xgo5/Ykl5Q3vUQ9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:CC497A4B6BF2F518|rigid:rdKKAw76ANLy7gOvCvNBuSeOxCY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q9Y4K3	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|ensembl:ENSP00000337853|ensembl:ENSP00000433623|uniprotkb:D3DR16	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341306|imex:IM-11696-448	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:NP_004611.1|refseq:NP_665802.1|ensembl:ENSG00000175104(gene)|ensembl:ENST00000348124(transcript)|ensembl:ENST00000526995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|go:"GO:0070534"(protein K63-linked ubiquitination)|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|go:"GO:0070555"(response to interleukin-1)|rcsb pdb:7L3L|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|go:"GO:0071222"(cellular response to lipopolysaccharide)|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-975871|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|dip:DIP-27515N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606	intact-crc:409933BBB1548DAC|rigid:gAlEObvOnJR0Dw33XC1VKMcErGk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95376	uniprotkb:P61077	intact:EBI-711158|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9|ensembl:ENSP00000348769|ensembl:ENSP00000403222	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341315|imex:IM-11696-451	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|ensembl:ENSG00000177479(gene)|ensembl:ENST00000356401(transcript)|ensembl:ENST00000449376(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|refseq:XP_016861020.1|refseq:XP_016861021.1	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:B5C1B18988D86D15|rigid:lA2BOmMboY/y0J9BXCEsi60q80I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q14258	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-2341129|intact:EBI-28973868|ensembl:ENSP00000323889|ensembl:ENSP00000445961	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:tri25_human(display_long)|uniprotkb:TRIM25(gene name)|psi-mi:TRIM25(display_short)|uniprotkb:EFP(gene name synonym)|uniprotkb:RNF147(gene name synonym)|uniprotkb:ZNF147(gene name synonym)|uniprotkb:Zinc finger protein 147(gene name synonym)|uniprotkb:Estrogen-responsive finger protein(gene name synonym)|uniprotkb:RING finger protein 147(gene name synonym)|uniprotkb:Ubiquitin/ISG15-conjugating enzyme TRIM25(gene name synonym)|uniprotkb:Tripartite motif-containing protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM25(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341309|imex:IM-11696-449	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	ensembl:ENSP00000323889|ensembl:ENSP00000445961|refseq:NP_005073.2|ensembl:ENSG00000121060(gene)|ensembl:ENST00000316881(transcript)|ensembl:ENST00000537230(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016604"(nuclear body)|go:"GO:0016874"(ligase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033280"(response to vitamin D)|go:"GO:0039552"(RIG-I binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043627"(response to estrogen)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|go:"GO:1902187"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042753|interpro:IPR043136|mint:Q14258|rcsb pdb:4CFG|rcsb pdb:4LTB|rcsb pdb:5EYA|rcsb pdb:5FER|rcsb pdb:5NT1|rcsb pdb:5NT2|rcsb pdb:6FLM|rcsb pdb:6FLN|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-5689896|reactome:R-HSA-877300|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:NhFfC0IxHvxPIt2YnKCPsPKuiQA9606	intact-crc:DC2D8C37C7CFDDC4|rigid:8clCGfXRwgWTRsgSaZat/6UXRZ4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q12899	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-2341136|intact:EBI-2802887|uniprotkb:A6NG96|uniprotkb:Q5SRL2|ensembl:ENSP00000331131|ensembl:ENSP00000373102|ensembl:ENSP00000379806|ensembl:ENSP00000389203|ensembl:ENSP00000390258|ensembl:ENSP00000391879|ensembl:ENSP00000392805|ensembl:ENSP00000393011|ensembl:ENSP00000394371|ensembl:ENSP00000394421|ensembl:ENSP00000395491|ensembl:ENSP00000396188|ensembl:ENSP00000398545|ensembl:ENSP00000402395|ensembl:ENSP00000406707|ensembl:ENSP00000407294|ensembl:ENSP00000407876|ensembl:ENSP00000408233|ensembl:ENSP00000409182|ensembl:ENSP00000410446|ensembl:ENSP00000414248|ensembl:ENSP00000415328|ensembl:ENSP00000415755|ensembl:ENSP00000416737	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:tri26_human(display_long)|uniprotkb:TRIM26(gene name)|psi-mi:TRIM26(display_short)|uniprotkb:RNF95(gene name synonym)|uniprotkb:ZNF173(gene name synonym)|uniprotkb:Zinc finger protein 173(gene name synonym)|uniprotkb:Acid finger protein(gene name synonym)|uniprotkb:RING finger protein 95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341312|imex:IM-11696-450	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:XP_006715243.1|refseq:NP_001229712.1|refseq:NP_003440.1|refseq:XP_005249431.1|refseq:XP_005249432.1|refseq:XP_005249433.1|refseq:XP_005249434.1|refseq:XP_005249435.1|dip:DIP-52853N|ensembl:ENSG00000137313(gene)|ensembl:ENSG00000226060(gene)|ensembl:ENSG00000228881(gene)|ensembl:ENSG00000230230(gene)|ensembl:ENSG00000231002(gene)|ensembl:ENSG00000231641(gene)|ensembl:ENSG00000234046(gene)|ensembl:ENSG00000234127(gene)|ensembl:ENST00000327357(transcript)|ensembl:ENST00000383607(transcript)|ensembl:ENST00000396558(transcript)|ensembl:ENST00000415923(transcript)|ensembl:ENST00000422349(transcript)|ensembl:ENST00000425523(transcript)|ensembl:ENST00000425831(transcript)|ensembl:ENST00000427535(transcript)|ensembl:ENST00000428486(transcript)|ensembl:ENST00000432326(transcript)|ensembl:ENST00000433314(transcript)|ensembl:ENST00000436219(transcript)|ensembl:ENST00000437089(transcript)|ensembl:ENST00000438384(transcript)|ensembl:ENST00000438908(transcript)|ensembl:ENST00000439094(transcript)|ensembl:ENST00000445259(transcript)|ensembl:ENST00000447711(transcript)|ensembl:ENST00000450392(transcript)|ensembl:ENST00000453195(transcript)|ensembl:ENST00000454678(transcript)|ensembl:ENST00000455000(transcript)|ensembl:ENST00000456093(transcript)|ensembl:ENST00000456770(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR043136|mint:Q12899|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:GPu3YgJ3xR1pN/MM9IKU3unCj1A9606	intact-crc:F2ADF9003E68B349|rigid:Sm3vnR4Jn9NB48VR4W2Z5DaJWTQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60291	uniprotkb:P61077	intact:EBI-2129851|uniprotkb:A4URL3|uniprotkb:A4URL4|uniprotkb:Q86W76|intact:EBI-28986785|ensembl:ENSP00000382487	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:mgrn1_human(display_long)|uniprotkb:MGRN1(gene name)|psi-mi:MGRN1(display_short)|uniprotkb:KIAA0544(gene name synonym)|uniprotkb:RNF156(gene name synonym)|uniprotkb:Mahogunin RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 156(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MGRN1(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341324|imex:IM-11696-454	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001135761.2|refseq:NP_001135762.1|refseq:NP_001135763.2|refseq:NP_056061.1|ensembl:ENST00000262370|ensembl:ENSP00000262370|ensembl:ENSP00000382487|ensembl:ENST00000415496|ensembl:ENSP00000393311|ensembl:ENST00000586183|ensembl:ENSP00000465860|ensembl:ENST00000588994|ensembl:ENSP00000468819|refseq:XP_005255277.1|refseq:XP_005255278.1|ensembl:ENSG00000102858(gene)|ensembl:ENST00000399577(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:UuLoCnlkpTBs/rmGgpQvgiMNuNE9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:1A48F9C64F00DE10|rigid:T8oIXftpmfZ9o6EfIdYqxuoVIy8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZY9	uniprotkb:P61077	intact:EBI-747544|uniprotkb:Q53H52|uniprotkb:Q5RI37|uniprotkb:Q5SRJ7|uniprotkb:Q5SRJ8|uniprotkb:Q5SS28|uniprotkb:Q96AK4|uniprotkb:Q96AP8|uniprotkb:Q99579|uniprotkb:Q9BZY8|uniprotkb:A6NLX6|uniprotkb:A9R9Q4|ensembl:ENSP00000350182|ensembl:ENSP00000365924|ensembl:ENSP00000390551|ensembl:ENSP00000391685|ensembl:ENSP00000398677|ensembl:ENSP00000409501	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:tri31_human(display_long)|uniprotkb:TRIM31(gene name)|psi-mi:TRIM31(display_short)|uniprotkb:C6orf13(gene name synonym)|uniprotkb:RNF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 31(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM31(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341318|imex:IM-11696-452	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008959.3|ensembl:ENSG00000137397(gene)|ensembl:ENSG00000204616(gene)|ensembl:ENSG00000223531(gene)|ensembl:ENSG00000224168(gene)|ensembl:ENSG00000225130(gene)|ensembl:ENSG00000233573(gene)|ensembl:ENST00000357569(transcript)|ensembl:ENST00000376734(transcript)|ensembl:ENST00000433864(transcript)|ensembl:ENST00000445679(transcript)|ensembl:ENST00000449412(transcript)|ensembl:ENST00000453266(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR020457|rcsb pdb:2YSJ|rcsb pdb:2YSL|reactome:R-HSA-877300	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:f7qMSpsjq1gDv+rl2o2BWpXhvKw9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:37049D3BA5CD1285|rigid:hylz8MuiNsC66seI5TVpS6A6fyc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q9UPQ4	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-2130401|uniprotkb:Q86XQ0|uniprotkb:Q8WVA4|ensembl:ENSP00000301924	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:tri35_human(display_long)|uniprotkb:TRIM35(gene name)|psi-mi:TRIM35(display_short)|uniprotkb:HLS5(gene name synonym)|uniprotkb:KIAA1098(gene name synonym)|uniprotkb:Hemopoietic lineage switch protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341321|imex:IM-11696-453	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:NP_741983.2|ensembl:ENSG00000104228(gene)|ensembl:ENST00000305364(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR043136|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:VlC2XEURqN7nMIfIns2E0QVsL7k9606	intact-crc:ADD9F883038B8CC5|rigid:cywqWoOU2OdedQVrBOQRTsmTHBQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q9NVW2	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-1996544|uniprotkb:Q9Y598|uniprotkb:Q96D38|uniprotkb:D3DTE0|uniprotkb:B2RBQ1|ensembl:ENSP00000253571|ensembl:ENSP00000328059	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:rnf12_human(display_long)|uniprotkb:RLIM(gene name)|psi-mi:RLIM(display_short)|uniprotkb:RNF12(gene name synonym)|uniprotkb:RING finger protein 12(gene name synonym)|uniprotkb:LIM domain-interacting RING finger protein(gene name synonym)|uniprotkb:RING finger LIM domain-binding protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-43(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RLIM(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341333|imex:IM-11696-457	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:NP_057204.2|refseq:NP_899196.1|ensembl:ENSG00000131263(gene)|ensembl:ENST00000332687(transcript)|ensembl:ENST00000349225(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060816"(random inactivation of X chromosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900095"(regulation of dosage compensation by inactivation of X chromosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NVW2|rcsb pdb:6W7Z|rcsb pdb:6W9A|rcsb pdb:6W9D|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:jEHiOt7hjZc5HU6E/XQGE7zdZbw9606	intact-crc:9037E938E6EB49A4|rigid:6zZJLXesmC6dhlyU+JKf80eLZik	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C040	uniprotkb:P61077	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341327|imex:IM-11696-455	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:1F1CC905E5C7CA53|rigid:nUw3b0XNsFvbSVWzB5bLkhD0FU8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q9Y577	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-743894|uniprotkb:B4DVJ2|uniprotkb:Q5VST8|ensembl:ENSP00000295033|ensembl:ENSP00000355658|ensembl:ENSP00000355659|ensembl:ENSP00000493891|ensembl:ENSP00000495842|ensembl:ENSP00000496098	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:tri17_human(display_long)|uniprotkb:Testis RING finger protein(gene name synonym)|uniprotkb:RING finger protein 16(gene name synonym)|uniprotkb:TRIM17(gene name)|psi-mi:TRIM17(display_short)|uniprotkb:RBCC(gene name synonym)|uniprotkb:RNF16(gene name synonym)|uniprotkb:TERF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 17(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM17(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341330|imex:IM-11696-456	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	ensembl:ENSG00000162931(gene)|ensembl:ENSG00000285344(gene)|refseq:NP_001020111.1|refseq:NP_001128327.1|refseq:NP_057186.1|refseq:XP_011542511.1|refseq:XP_011542512.1|refseq:XP_006711842.1|ensembl:ENST00000295033(transcript)|ensembl:ENST00000366697(transcript)|ensembl:ENST00000366698(transcript)|ensembl:ENST00000645562(transcript)|ensembl:ENST00000645958(transcript)|ensembl:ENST00000647385(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045087"(innate immune response)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032918|interpro:IPR035687|interpro:IPR043136|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:pXiCDkeNMtq9icQduH4MSCM6vSQ9606	intact-crc:0A45DA8ADC6491A4|rigid:tzNa8SpCKQ8MCLOO7lslNHWI1BM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EP1	uniprotkb:P61077	intact:EBI-718923|uniprotkb:A6NEN5|uniprotkb:Q96SL3|uniprotkb:Q9NRT4|uniprotkb:Q9NT32|uniprotkb:Q9NVD5|uniprotkb:B4DZ77|uniprotkb:B4E2L6|ensembl:ENSP00000392395	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:chfr_human(display_long)|uniprotkb:Checkpoint with forkhead and RING finger domains protein(gene name synonym)|uniprotkb:RING finger protein 196(gene name synonym)|uniprotkb:CHFR(gene name)|psi-mi:CHFR(display_short)|uniprotkb:RNF196(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHFR(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341342|imex:IM-11696-176	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154816.1|refseq:NP_001154817.1|refseq:NP_001154818.1|refseq:NP_001154819.1|refseq:NP_060693.2|ensembl:ENSG00000072609(gene)|ensembl:ENST00000432561(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR019406|interpro:IPR040909|rcsb pdb:1LGP|rcsb pdb:1LGQ|rcsb pdb:2XOC|rcsb pdb:2XOY|rcsb pdb:2XOZ|rcsb pdb:2XP0|dip:DIP-40098N	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid://FU72n6rmuPAu+Fjm377S4nEjw9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:EBDF08B4541BBD25|rigid:cN8vny93rEVj9VLgbR6x8FlkZbc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NZS9	uniprotkb:P61077	intact:EBI-2130199|uniprotkb:A8K4Z9|uniprotkb:D3DUG8|uniprotkb:B4DUT0|ensembl:ENSP00000261658|ensembl:ENSP00000478190	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:bfar_human(display_long)|uniprotkb:BFAR(gene name)|psi-mi:BFAR(display_short)|uniprotkb:BAR(gene name synonym)|uniprotkb:RNF47(gene name synonym)|uniprotkb:RING finger protein 47(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341336|imex:IM-11696-174	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057645.1|refseq:XP_005255407.1|ensembl:ENSG00000103429(gene)|ensembl:ENSG00000275618(gene)|ensembl:ENST00000261658(transcript)|ensembl:ENST00000619034(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017907	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:XDPFsRmdbch1NXffLOcE0lVrtRo9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:2AB08AB12299F8E0|rigid:7dAjHqPLqttimvVpFRZTDlKoD8M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EQ8	uniprotkb:P61077	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341339|imex:IM-11696-175	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:80EAEEBF620D09F6|rigid:VAFwmQH8RdPYPjZiTHwFrM6X/aQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BYV6	uniprotkb:P61077	intact:EBI-2341179|uniprotkb:Q96DV3|uniprotkb:Q9BYV5|uniprotkb:Q8IUD9|uniprotkb:Q8IUE4|uniprotkb:Q96DV2|uniprotkb:Q53XX3|uniprotkb:B3KRC0|uniprotkb:B3KRJ3|ensembl:ENSP00000323913	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:tri55_human(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341345|imex:IM-11696-177	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011515915.1|refseq:XP_011515916.1|refseq:XP_011515917.1|refseq:XP_011515918.1|refseq:NP_149047.2|refseq:NP_908973.1|refseq:NP_908974.1|refseq:NP_908975.1|ensembl:ENSG00000147573(gene)|ensembl:ENST00000315962(transcript)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0050904"(diapedesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1905517"(macrophage migration)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR033492|mint:Q9BYV6	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:MiXH7mPPLOjav9yf0/HL7neg3yI9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:B5BE8465CD060CED|rigid:PBcVw0uaeLijCT2Y/ecMY3/S824	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C035	uniprotkb:P61077	intact:EBI-924214|uniprotkb:Q2MLV4|uniprotkb:Q2MLV8|uniprotkb:Q2MLV9|uniprotkb:Q2MLW1|uniprotkb:Q2MLW3|uniprotkb:Q2MLW4|uniprotkb:A6NGQ1|uniprotkb:Q2MLW6|uniprotkb:Q2MLW7|uniprotkb:Q2MLX1|uniprotkb:Q2MLX2|uniprotkb:Q2MLX3|uniprotkb:Q2MLX5|uniprotkb:Q2MLY3|uniprotkb:Q2MLY4|uniprotkb:Q2V6Q6|uniprotkb:Q6GX26|uniprotkb:Q8WU46|uniprotkb:Q96SR5|uniprotkb:Q9C031|uniprotkb:Q9C032|uniprotkb:Q9C033|uniprotkb:Q9C034|uniprotkb:A8WFA8|uniprotkb:D3DQS8|uniprotkb:D3DQS9|uniprotkb:G3GJY1|ensembl:ENSP00000369373|ensembl:ENSP00000507420	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:trim5_human(display_long)|uniprotkb:TRIM5(gene name)|psi-mi:TRIM5(display_short)|uniprotkb:RNF88(gene name synonym)|uniprotkb:RING finger protein 88(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM5(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341348|imex:IM-11696-178	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149023.2|refseq:NP_149083.2|refseq:NP_149084.2|refseq:XP_011518729.1|refseq:XP_005253240.1|refseq:XP_005253241.1|ensembl:ENSG00000132256(gene)|ensembl:ENST00000380034(transcript)|ensembl:ENST00000684655(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031664"(regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR043136|rcsb pdb:2ECV|rcsb pdb:2YRG|reactome:R-HSA-877300	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:t0YqhaJC8oQcwot7oks1LgMxdNc9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:DD2EBF77D6009825|rigid:y7hrvgRosUBQ1sVGNd2SEr88DRE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q96DX4	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-2341274|uniprotkb:Q8ND53|uniprotkb:Q6UX21|ensembl:ENSP00000377942|ensembl:ENSP00000443176	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:rspry_human(display_long)|uniprotkb:RSPRY1(gene name)|psi-mi:RSPRY1(display_short)|uniprotkb:KIAA1972(gene name synonym)|uniprotkb:UNQ328/PRO444(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341351|imex:IM-11696-179	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:NP_001292092.1|refseq:NP_001292093.1|refseq:NP_001292111.1|refseq:NP_588609.1|refseq:XP_005256277.1|ensembl:ENSG00000159579(gene)|ensembl:ENST00000394420(transcript)|ensembl:ENST00000537866(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035774|interpro:IPR043136	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:WIh5Nn9L+KH2Zw9m3M+sFpMo2/M9606	intact-crc:4D9628D9AC882078|rigid:wQTwebnyih2WT38A7EI8Pv1djSo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6UWE0	uniprotkb:P61077	intact:EBI-720984|uniprotkb:Q5VVV0|uniprotkb:Q8NB40|uniprotkb:Q96GT5|uniprotkb:Q96MX5|uniprotkb:Q96MZ7|ensembl:ENSP00000300417|ensembl:ENSP00000322937|ensembl:ENSP00000362419|ensembl:ENSP00000502167	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:lrsm1_human(display_long)|uniprotkb:Leucine-rich repeat and sterile alpha motif-containing protein 1(gene name synonym)|uniprotkb:Tsg101-associated ligase(gene name synonym)|uniprotkb:LRSAM1(gene name)|psi-mi:LRSAM1(display_short)|uniprotkb:TAL(gene name synonym)|uniprotkb:UNQ6496/PRO21356(orf name)|uniprotkb:RING-type E3 ubiquitin transferase LRSAM1(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341354|imex:IM-11696-180	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005373.1|refseq:NP_001005374.1|refseq:NP_001177652.1|refseq:NP_612370.3|refseq:XP_016870772.1|ensembl:ENSG00000148356(gene)|ensembl:ENST00000300417(transcript)|ensembl:ENST00000323301(transcript)|ensembl:ENST00000373322(transcript)|ensembl:ENST00000675448(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0046755"(viral budding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032675|mint:Q6UWE0|reactome:R-HSA-983168	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:qkwPqOsfNjZBB2Xp6YAA9FbEZxM9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:D73E77FBF33DCE0F|rigid:JQupWT3+6X/3tSWQfuwuut+plB4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H0F5	uniprotkb:P61077	intact:EBI-2341200|uniprotkb:Q8N0Y0|uniprotkb:A6PVP9|uniprotkb:B1AM82|uniprotkb:Q7LB33|ensembl:ENSP00000259605|uniprotkb:B1AM81|uniprotkb:B3KSG4|uniprotkb:E7EVL3|uniprotkb:Q9H748	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:rnf38_human(display_long)|uniprotkb:RING finger protein 38(gene name synonym)|uniprotkb:RNF38(gene name)|psi-mi:RNF38(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF38(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341363|imex:IM-11696-183	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011516014.1|refseq:XP_011516015.1|refseq:XP_006716784.1|refseq:NP_073618.3|refseq:NP_919309.1|refseq:NP_919310.1|refseq:NP_919311.1|refseq:NP_919313.1|ensembl:ENSG00000137075(gene)|ensembl:ENST00000259605(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008584"(male gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|go:"GO:0036126"(sperm flagellum)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9H0F5|rcsb pdb:1X4J|rcsb pdb:4V3K|rcsb pdb:4V3L|ensembl:ENSP00000259605|ensembl:ENST00000350199|ensembl:ENSP00000343947|ensembl:ENST00000353739|ensembl:ENSP00000335239|ensembl:ENST00000357058|ensembl:ENSP00000349566|ensembl:ENST00000377877|ensembl:ENSP00000367109|ensembl:ENST00000377885|ensembl:ENSP00000367117|ensembl:ENST00000611646|ensembl:ENSP00000483536|refseq:XP_005251423.1|refseq:XP_005251424.1|refseq:XP_005251425.1|refseq:XP_016869784.1	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:leJgsTFAtsRhHPh44pbrpk1wkDo9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:7EAE3CC047C998C7|rigid:igomLJdl5+ml1lOvm+/Cw+aPZD8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61077	uniprotkb:Q96P09	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-2341055|uniprotkb:Q96RW5|uniprotkb:Q6IPY1	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:birc8_human(display_long)|uniprotkb:BIRC8(gene name)|psi-mi:BIRC8(display_short)|uniprotkb:ILP2(gene name synonym)|uniprotkb:Inhibitor of apoptosis-like protein 2(gene name synonym)|uniprotkb:Testis-specific inhibitor of apoptosis(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341357|imex:IM-11696-181	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	interpro:IPR042579|refseq:NP_203127.3|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:1XB0|rcsb pdb:1XB1|interpro:IPR011029(DEATH-like)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:dNa54zbu4SMSRJ8FXGBLuqGJ0qo9606	intact-crc:65915E0469D1D856|rigid:BCFtKwXgNFVM5gbm4XG81Ajrt1Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86UD3	uniprotkb:P61077	intact:EBI-2341065|uniprotkb:A8K264|uniprotkb:B9EJE7|ensembl:ENSP00000309141	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:marh3_human(display_long)|uniprotkb:MARCHF3(gene name)|psi-mi:MARCHF3(display_short)|uniprotkb:MARCH3(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 3(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein III(gene name synonym)|uniprotkb:RING finger protein 173(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF3(gene name synonym)|uniprotkb:RNF173(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341360|imex:IM-11696-182	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_848545.1|ensembl:ENSG00000173926(gene)|ensembl:ENST00000308660(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:uv/JcWUoL549NACFaOUs/oLdHuI9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:F565BDF1EEF3BB0B|rigid:Fh87/GwL52OVK0luiXjO1Bg57q8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:P78317	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-2340927|uniprotkb:Q49AR8|uniprotkb:B2R6D6|uniprotkb:D6RF58|intact:EBI-28970119|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:rnf4_human(display_long)|uniprotkb:SNURF(gene name synonym)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:RNF4(gene name)|psi-mi:RNF4(display_short)|uniprotkb:RES4-26(orf name)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341372|imex:IM-11696-186	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_001171938.1|refseq:NP_001171939.1|refseq:NP_002929.1|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503|ensembl:ENST00000511859|ensembl:ENSP00000426615|ensembl:ENST00000541204|ensembl:ENSP00000446369|ensembl:ENSG00000063978(gene)|ensembl:ENST00000314289(transcript)|ensembl:ENST00000506706(transcript)|ensembl:ENST00000511600(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|go:"GO:1990752"(microtubule end)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|mint:P78317|rcsb pdb:2EA6|rcsb pdb:2XEU|rcsb pdb:4PPE|reactome:R-HSA-5693607|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:Yhu2iAaNQYcfGdYohDPBdhMFEpc9606	intact-crc:F55C898CD9517262|rigid:YRuP9OPNIbUh8zLa86lnvIVorxY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:O15344	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-2340316|uniprotkb:Q9BZX5|uniprotkb:O75361|uniprotkb:B2RCG2|ensembl:ENSP00000312678|ensembl:ENSP00000370156|ensembl:ENSP00000370157|ensembl:ENSP00000370162|ensembl:ENSP00000370164|ensembl:ENSP00000414521	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:tri18_human(display_long)|uniprotkb:MID1(gene name)|psi-mi:MID1(display_short)|uniprotkb:FXY(gene name synonym)|uniprotkb:RNF59(gene name synonym)|uniprotkb:TRIM18(gene name synonym)|uniprotkb:XPRF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 18(gene name synonym)|uniprotkb:Putative transcription factor XPRF(gene name synonym)|uniprotkb:Midin(gene name synonym)|uniprotkb:RING finger protein 59(gene name synonym)|uniprotkb:RING finger protein Midline-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Midline-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341366|imex:IM-11696-184	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_000372.1|refseq:NP_001092094.1|refseq:NP_001180206.1|refseq:NP_001180207.1|refseq:NP_001180208.1|refseq:NP_001180209.1|refseq:NP_001180210.1|refseq:NP_150632.1|refseq:NP_001334662.1|refseq:XP_016885025.1|refseq:XP_016885029.1|ensembl:ENSG00000101871(gene)|ensembl:ENST00000317552(transcript)|ensembl:ENST00000380779(transcript)|ensembl:ENST00000380780(transcript)|ensembl:ENST00000380785(transcript)|ensembl:ENST00000380787(transcript)|ensembl:ENST00000453318(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016740"(transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003649(B-box, C-terminal)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR027727|interpro:IPR036116|interpro:IPR040859|interpro:IPR043136|rcsb pdb:2DQ5|rcsb pdb:2FFW|rcsb pdb:2JUN|rcsb pdb:5IM8|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:NGlMGyFT7GEcrzVR/Iw4LitMBig9606	intact-crc:E0A0B59D4ABBFAF0|rigid:kK43qQZLPOz94YWlkLhA0x6ZsVI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06587	uniprotkb:P51965	intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym)	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341369|imex:IM-11696-185	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	intact-crc:C37FA9301D7094FB|rigid:mYbLI5fxKPh9MAhM3Nrw/vnlhuw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q13064	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-2340269|ensembl:ENSP00000313881	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341375|imex:IM-11696-187	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606	intact-crc:F95C4D1D1BCD8739|rigid:BVW58PokaovQdHb6ZhxQRPgdc8w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q86Y13	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341378|imex:IM-11696-188	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:3AC34E76E589D620|rigid:8/u+h6IAKGDCi7ArqQst8RI6Ei4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95376	uniprotkb:P51965	intact:EBI-711158|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9|ensembl:ENSP00000348769|ensembl:ENSP00000403222	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym)	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341381|imex:IM-11696-458	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|ensembl:ENSG00000177479(gene)|ensembl:ENST00000356401(transcript)|ensembl:ENST00000449376(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|refseq:XP_016861020.1|refseq:XP_016861021.1	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	intact-crc:B167ABDB1FEEA93D|rigid:N5MdjVhI1bH66bNlu1EwYHfpifA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:O94941	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-751901|uniprotkb:Q6IAR5|uniprotkb:Q86X87|uniprotkb:Q9H4J2|ensembl:ENSP00000217173	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:rnf37_human(display_long)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 5(gene name synonym)|uniprotkb:U-box domain-containing protein 5(gene name synonym)|uniprotkb:UBOX5(gene name)|psi-mi:UBOX5(display_short)|uniprotkb:KIAA0860(gene name synonym)|uniprotkb:RNF37(gene name synonym)|uniprotkb:UBCE7IP5(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF37(gene name synonym)|uniprotkb:UIP5(gene name synonym)|uniprotkb:UbcM4-interacting protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341384|imex:IM-11696-459	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_055763.1|refseq:NP_955447.1|ensembl:ENSG00000185019(gene)|ensembl:ENST00000217173(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039847|interpro:IPR039925|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:bHUiSJ345KLIwL+xD2qH/CJVqL09606	intact-crc:2E40C2E2B2F21E56|rigid:svGLOG8LfDAB+sY8bYSnK9qZo1M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:O60291	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-2129851|uniprotkb:A4URL3|uniprotkb:A4URL4|uniprotkb:Q86W76|intact:EBI-28986785|ensembl:ENSP00000382487	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:mgrn1_human(display_long)|uniprotkb:MGRN1(gene name)|psi-mi:MGRN1(display_short)|uniprotkb:KIAA0544(gene name synonym)|uniprotkb:RNF156(gene name synonym)|uniprotkb:Mahogunin RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 156(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MGRN1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341387|imex:IM-11696-460	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_001135761.2|refseq:NP_001135762.1|refseq:NP_001135763.2|refseq:NP_056061.1|ensembl:ENST00000262370|ensembl:ENSP00000262370|ensembl:ENSP00000382487|ensembl:ENST00000415496|ensembl:ENSP00000393311|ensembl:ENST00000586183|ensembl:ENSP00000465860|ensembl:ENST00000588994|ensembl:ENSP00000468819|refseq:XP_005255277.1|refseq:XP_005255278.1|ensembl:ENSG00000102858(gene)|ensembl:ENST00000399577(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:UuLoCnlkpTBs/rmGgpQvgiMNuNE9606	intact-crc:1EEEE394D8361A38|rigid:XzQ9kwwvBGS+MsB83/Ny12e+a5Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C040	uniprotkb:P51965	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341390|imex:IM-11696-461	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	intact-crc:A32CC8123855829E|rigid:QPOR4GKeQ7fyE2dsmk+EHGBOR5U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y3C5	uniprotkb:P51965	intact:EBI-396669|intact:EBI-2129167|uniprotkb:A8KAI2|uniprotkb:Q5T7R8|ensembl:ENSP00000242719	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:rnf11_human(display_long)|uniprotkb:CGI-123(orf name)|uniprotkb:RNF11(gene name)|psi-mi:RNF11(display_short)	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341393|imex:IM-11696-462	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055187.1|ensembl:ENSP00000242719|ensembl:ENSG00000123091(gene)|ensembl:ENST00000242719(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042981|mint:Q9Y3C5	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Uj0YAf/t+AdYbMd6fgQ8hVKoP0w9606	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	intact-crc:50882E425CF9F52B|rigid:5xooB0iEpHyvn/Fuwzvpwb2iCkI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q9NVW2	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-1996544|uniprotkb:Q9Y598|uniprotkb:Q96D38|uniprotkb:D3DTE0|uniprotkb:B2RBQ1|ensembl:ENSP00000253571|ensembl:ENSP00000328059	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:rnf12_human(display_long)|uniprotkb:RLIM(gene name)|psi-mi:RLIM(display_short)|uniprotkb:RNF12(gene name synonym)|uniprotkb:RING finger protein 12(gene name synonym)|uniprotkb:LIM domain-interacting RING finger protein(gene name synonym)|uniprotkb:RING finger LIM domain-binding protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-43(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RLIM(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341396|imex:IM-11696-463	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_057204.2|refseq:NP_899196.1|ensembl:ENSG00000131263(gene)|ensembl:ENST00000332687(transcript)|ensembl:ENST00000349225(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060816"(random inactivation of X chromosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900095"(regulation of dosage compensation by inactivation of X chromosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NVW2|rcsb pdb:6W7Z|rcsb pdb:6W9A|rcsb pdb:6W9D|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:jEHiOt7hjZc5HU6E/XQGE7zdZbw9606	intact-crc:2C07E82F3B790169|rigid:JqQFi2PgOa0FEg8AWiSFLgsXJSw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6ZNA4	uniprotkb:P51965	intact:EBI-2129175|uniprotkb:Q6ZMU2|uniprotkb:Q7L428|uniprotkb:Q7Z346|uniprotkb:Q8N1P9|uniprotkb:Q8WUA3|uniprotkb:Q9NSR1|uniprotkb:Q6P9A4|uniprotkb:C9JUS4|uniprotkb:H0YN55|ensembl:ENSP00000452732|intact:EBI-28970158	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:rn111_human(display_long)|uniprotkb:RNF111(gene name)|psi-mi:RNF111(display_short)|uniprotkb:RING finger protein 111(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Arkadia(gene name synonym)	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341399|imex:IM-11696-464	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060080.6|ensembl:ENST00000348370|ensembl:ENSP00000288199|ensembl:ENSP00000452732|ensembl:ENST00000559209|ensembl:ENSP00000453872|ensembl:ENST00000561186|ensembl:ENSP00000453015|refseq:NP_001317260.1|refseq:XP_016877827.1|refseq:XP_006720642.1|refseq:NP_001257459.1|refseq:NP_001257457.1|refseq:NP_001257458.1|ensembl:ENSG00000157450(gene)|ensembl:ENST00000557998(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR029306|rcsb pdb:2KIZ|rcsb pdb:5LG0|rcsb pdb:5LG7|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-5696395|reactome:R-HSA-983168|go:"GO:0032184"(SUMO polymer binding)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:6SY5oMr5u4mnVi+zdRboVljMGa09606	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	intact-crc:41B9A43D572CF988|rigid:GKaJtEX41CYqg4vMD4JLFcQ7RWo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q6PCD5	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-2129159|uniprotkb:Q9H9Q3|uniprotkb:Q9NVT4|uniprotkb:Q5XKR3|uniprotkb:A8K585|uniprotkb:B2RE35|uniprotkb:D3DUJ8|ensembl:ENSP00000354361|ensembl:ENSP00000460049	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:rfwd3_human(display_long)|uniprotkb:RFWD3(gene name)|psi-mi:RFWD3(display_short)|uniprotkb:RING finger and WD repeat domain-containing protein 3(gene name synonym)|uniprotkb:RNF201(gene name synonym)|uniprotkb:RING finger protein 201(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341402|imex:IM-11696-465	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:XP_011521493.1|refseq:NP_060594.3|refseq:XP_016878880.1|refseq:XP_005256078.1|refseq:XP_005256079.1|dip:DIP-52688N|ensembl:ENSG00000168411(gene)|ensembl:ENST00000361070(transcript)|ensembl:ENST00000571750(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031297"(replication fork processing)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037381|rcsb pdb:6CVZ	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:r7gkMbkS0GKPVn9riLPR34KFaKk9606	intact-crc:FF2F970F9B8E63AD|rigid:Q4tWbUZYlEVOVlKL8AuzJyAcvlc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EP1	uniprotkb:P51965	intact:EBI-718923|uniprotkb:A6NEN5|uniprotkb:Q96SL3|uniprotkb:Q9NRT4|uniprotkb:Q9NT32|uniprotkb:Q9NVD5|uniprotkb:B4DZ77|uniprotkb:B4E2L6|ensembl:ENSP00000392395	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:chfr_human(display_long)|uniprotkb:Checkpoint with forkhead and RING finger domains protein(gene name synonym)|uniprotkb:RING finger protein 196(gene name synonym)|uniprotkb:CHFR(gene name)|psi-mi:CHFR(display_short)|uniprotkb:RNF196(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHFR(gene name synonym)	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341405|imex:IM-11696-466	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154816.1|refseq:NP_001154817.1|refseq:NP_001154818.1|refseq:NP_001154819.1|refseq:NP_060693.2|ensembl:ENSG00000072609(gene)|ensembl:ENST00000432561(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR019406|interpro:IPR040909|rcsb pdb:1LGP|rcsb pdb:1LGQ|rcsb pdb:2XOC|rcsb pdb:2XOY|rcsb pdb:2XOZ|rcsb pdb:2XP0|dip:DIP-40098N	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid://FU72n6rmuPAu+Fjm377S4nEjw9606	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	intact-crc:57EF09A38989F5E8|rigid:yVUkqIgRgE1fXyC5+h50ZmY8kVI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q96GF1	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-2340249|uniprotkb:A8K5C1|uniprotkb:A9X3T8|uniprotkb:Q8N900|ensembl:ENSP00000320508|ensembl:ENSP00000427755	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:rn185_human(display_long)|uniprotkb:RNF185(gene name)|psi-mi:RNF185(display_short)|uniprotkb:RING finger protein 185(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF185(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341414|imex:IM-11696-189	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_001129297.1|refseq:NP_689480.2|ensembl:ENSG00000138942(gene)|ensembl:ENST00000326132(transcript)|ensembl:ENST00000518626(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:ivzbt31KPTKL/Rc1Wzs3h80XJac9606	intact-crc:321920C11FA6B66B|rigid:pUc6kneEP+5tUAngjXohNCRLGl4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y508	uniprotkb:P51965	intact:EBI-723587|uniprotkb:Q6N0B0|uniprotkb:B2RDQ9|uniprotkb:B4DWY5|uniprotkb:E1P627|ensembl:ENSP00000244061	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:rn114_human(display_long)|uniprotkb:Zinc finger protein 313(gene name synonym)|uniprotkb:RNF114(gene name)|psi-mi:RNF114(display_short)|uniprotkb:ZNF313(gene name synonym)|uniprotkb:ZNF228(gene name synonym)|uniprotkb:Zinc finger protein 228(gene name synonym)|uniprotkb:RING finger protein 114(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF114(gene name synonym)	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341408|imex:IM-11696-467	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061153.1|ensembl:ENSG00000124226(gene)|ensembl:ENST00000244061(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR034734|interpro:IPR042716|reactome:R-HSA-983168	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:R1fX8xaGuIhy/M6cLzPeyfJBf649606	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	intact-crc:24E3A7AF955B2BB8|rigid:1vh/apGSKYUx37W6FFaTo/pG52c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q6UWE0	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-720984|uniprotkb:Q5VVV0|uniprotkb:Q8NB40|uniprotkb:Q96GT5|uniprotkb:Q96MX5|uniprotkb:Q96MZ7|ensembl:ENSP00000300417|ensembl:ENSP00000322937|ensembl:ENSP00000362419|ensembl:ENSP00000502167	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:lrsm1_human(display_long)|uniprotkb:Leucine-rich repeat and sterile alpha motif-containing protein 1(gene name synonym)|uniprotkb:Tsg101-associated ligase(gene name synonym)|uniprotkb:LRSAM1(gene name)|psi-mi:LRSAM1(display_short)|uniprotkb:TAL(gene name synonym)|uniprotkb:UNQ6496/PRO21356(orf name)|uniprotkb:RING-type E3 ubiquitin transferase LRSAM1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341411|imex:IM-11696-468	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_001005373.1|refseq:NP_001005374.1|refseq:NP_001177652.1|refseq:NP_612370.3|refseq:XP_016870772.1|ensembl:ENSG00000148356(gene)|ensembl:ENST00000300417(transcript)|ensembl:ENST00000323301(transcript)|ensembl:ENST00000373322(transcript)|ensembl:ENST00000675448(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0046755"(viral budding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032675|mint:Q6UWE0|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:qkwPqOsfNjZBB2Xp6YAA9FbEZxM9606	intact-crc:6B0E76EC2EAF86C2|rigid:Ey9Mg/Ok4cKQL8paP+YWBBD/xrY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q8N9I9	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-2340258|uniprotkb:Q8NDS8|uniprotkb:Q8NAU6|uniprotkb:Q53ZZ2|ensembl:ENSP00000338050|ensembl:ENSP00000447873|ensembl:ENSP00000449294	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:dtx3_human(display_long)|uniprotkb:DTX3(gene name)|psi-mi:DTX3(display_short)|uniprotkb:RNF154(gene name synonym)|uniprotkb:RING finger protein 154(gene name synonym)|uniprotkb:Protein deltex-3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341423|imex:IM-11696-192	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_001273174.1|refseq:NP_001273175.1|refseq:XP_011536324.1|refseq:NP_848597.1|refseq:XP_005268754.1|refseq:XP_005268755.1|refseq:XP_005268757.1|refseq:XP_005268760.1|ensembl:ENSG00000178498(gene)|ensembl:ENST00000337737(transcript)|ensembl:ENST00000548198(transcript)|ensembl:ENST00000548804(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:Ma7JBhgMdFofCeWESbf8h1iLAHY9606	intact-crc:D6A56A160A55CD04|rigid:U1CYecCO8vYgen8Fv7k+qCtXh64	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51965	uniprotkb:Q96P09	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-2341055|uniprotkb:Q96RW5|uniprotkb:Q6IPY1	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:birc8_human(display_long)|uniprotkb:BIRC8(gene name)|psi-mi:BIRC8(display_short)|uniprotkb:ILP2(gene name synonym)|uniprotkb:Inhibitor of apoptosis-like protein 2(gene name synonym)|uniprotkb:Testis-specific inhibitor of apoptosis(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341417|imex:IM-11696-190	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	interpro:IPR042579|refseq:NP_203127.3|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:1XB0|rcsb pdb:1XB1|interpro:IPR011029(DEATH-like)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:dNa54zbu4SMSRJ8FXGBLuqGJ0qo9606	intact-crc:D9A15F13B443909B|rigid:WFzXYCPRuXIU3AK3FmqOMI8Pr4s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86UD3	uniprotkb:P51965	intact:EBI-2341065|uniprotkb:A8K264|uniprotkb:B9EJE7|ensembl:ENSP00000309141	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:marh3_human(display_long)|uniprotkb:MARCHF3(gene name)|psi-mi:MARCHF3(display_short)|uniprotkb:MARCH3(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 3(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein III(gene name synonym)|uniprotkb:RING finger protein 173(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF3(gene name synonym)|uniprotkb:RNF173(gene name synonym)	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341420|imex:IM-11696-191	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_848545.1|ensembl:ENSG00000173926(gene)|ensembl:ENST00000308660(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:uv/JcWUoL549NACFaOUs/oLdHuI9606	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	intact-crc:4955BCE63361F3C6|rigid:wDFDmgHOQkAU9yvmLCfApzLcgbc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LR5	uniprotkb:P98170	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341426|imex:IM-11696-193	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	intact-crc:60C14B24721C6982|rigid:EAF/YjJE1h8nCQNADupFFziu77g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LR5	uniprotkb:O15344	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-2340316|uniprotkb:Q9BZX5|uniprotkb:O75361|uniprotkb:B2RCG2|ensembl:ENSP00000312678|ensembl:ENSP00000370156|ensembl:ENSP00000370157|ensembl:ENSP00000370162|ensembl:ENSP00000370164|ensembl:ENSP00000414521	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:tri18_human(display_long)|uniprotkb:MID1(gene name)|psi-mi:MID1(display_short)|uniprotkb:FXY(gene name synonym)|uniprotkb:RNF59(gene name synonym)|uniprotkb:TRIM18(gene name synonym)|uniprotkb:XPRF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 18(gene name synonym)|uniprotkb:Putative transcription factor XPRF(gene name synonym)|uniprotkb:Midin(gene name synonym)|uniprotkb:RING finger protein 59(gene name synonym)|uniprotkb:RING finger protein Midline-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Midline-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341429|imex:IM-11696-194	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	refseq:NP_000372.1|refseq:NP_001092094.1|refseq:NP_001180206.1|refseq:NP_001180207.1|refseq:NP_001180208.1|refseq:NP_001180209.1|refseq:NP_001180210.1|refseq:NP_150632.1|refseq:NP_001334662.1|refseq:XP_016885025.1|refseq:XP_016885029.1|ensembl:ENSG00000101871(gene)|ensembl:ENST00000317552(transcript)|ensembl:ENST00000380779(transcript)|ensembl:ENST00000380780(transcript)|ensembl:ENST00000380785(transcript)|ensembl:ENST00000380787(transcript)|ensembl:ENST00000453318(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016740"(transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003649(B-box, C-terminal)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR027727|interpro:IPR036116|interpro:IPR040859|interpro:IPR043136|rcsb pdb:2DQ5|rcsb pdb:2FFW|rcsb pdb:2JUN|rcsb pdb:5IM8|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:NGlMGyFT7GEcrzVR/Iw4LitMBig9606	intact-crc:88CEEED171DE910D|rigid:50NTYBBCQ8H/jw/7D3MRjWwte1s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LR5	uniprotkb:Q13064	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-2340269|ensembl:ENSP00000313881	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341438|imex:IM-11696-197	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606	intact-crc:966E1B80509527DE|rigid:ufPFdIqjSZS9eOwFLv+tA59qT+Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LR5	uniprotkb:Q06587	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341432|imex:IM-11696-195	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606	intact-crc:B9FC3FEF9451E0F6|rigid:zmC5HzW56z04e4x3XqFa+yrLbxY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P78317	uniprotkb:Q96LR5	intact:EBI-2340927|uniprotkb:Q49AR8|uniprotkb:B2R6D6|uniprotkb:D6RF58|intact:EBI-28970119|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:rnf4_human(display_long)|uniprotkb:SNURF(gene name synonym)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:RNF4(gene name)|psi-mi:RNF4(display_short)|uniprotkb:RES4-26(orf name)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341435|imex:IM-11696-196	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171938.1|refseq:NP_001171939.1|refseq:NP_002929.1|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503|ensembl:ENST00000511859|ensembl:ENSP00000426615|ensembl:ENST00000541204|ensembl:ENSP00000446369|ensembl:ENSG00000063978(gene)|ensembl:ENST00000314289(transcript)|ensembl:ENST00000506706(transcript)|ensembl:ENST00000511600(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|go:"GO:1990752"(microtubule end)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|mint:P78317|rcsb pdb:2EA6|rcsb pdb:2XEU|rcsb pdb:4PPE|reactome:R-HSA-5693607|reactome:R-HSA-983168	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Yhu2iAaNQYcfGdYohDPBdhMFEpc9606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:173302DD8C6DAB85|rigid:xHmwNj2JbOhlKwAVda5pjPd2xTU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LR5	uniprotkb:O94941	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-751901|uniprotkb:Q6IAR5|uniprotkb:Q86X87|uniprotkb:Q9H4J2|ensembl:ENSP00000217173	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:rnf37_human(display_long)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 5(gene name synonym)|uniprotkb:U-box domain-containing protein 5(gene name synonym)|uniprotkb:UBOX5(gene name)|psi-mi:UBOX5(display_short)|uniprotkb:KIAA0860(gene name synonym)|uniprotkb:RNF37(gene name synonym)|uniprotkb:UBCE7IP5(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF37(gene name synonym)|uniprotkb:UIP5(gene name synonym)|uniprotkb:UbcM4-interacting protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341444|imex:IM-11696-198	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	refseq:NP_055763.1|refseq:NP_955447.1|ensembl:ENSG00000185019(gene)|ensembl:ENST00000217173(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039847|interpro:IPR039925|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:bHUiSJ345KLIwL+xD2qH/CJVqL09606	intact-crc:462E99AE899775AB|rigid:z65pTaqIYxTeNm1qt1KtDZVhzss	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5U6	uniprotkb:Q96LR5	intact:EBI-714023|uniprotkb:Q92550|uniprotkb:Q9NPP8|uniprotkb:Q9ULW4|ensembl:ENSP00000322242	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:rnf10_human(display_long)|uniprotkb:RNF10(gene name)|psi-mi:RNF10(display_short)|uniprotkb:KIAA0262(gene name synonym)|uniprotkb:RIE2(gene name synonym)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341441|imex:IM-11696-469	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055683.3|refseq:NP_001317403.1|ensembl:ENSG00000022840(gene)|ensembl:ENST00000325954(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039739|mint:Q8N5U6	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Bca0Ae456x1eCsdlduoCbn7coUQ9606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:3106BCA44F07DE6A|rigid:8FOAq1E1j9VdMqo4Ikz02OSvEbc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LR5	uniprotkb:Q9C040	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341447|imex:IM-11696-470	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	intact-crc:D35D8F116D57D2FA|rigid:Wbzp2BwI8RRS96x+tb/swKVBnyQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LR5	uniprotkb:Q9NVW2	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-1996544|uniprotkb:Q9Y598|uniprotkb:Q96D38|uniprotkb:D3DTE0|uniprotkb:B2RBQ1|ensembl:ENSP00000253571|ensembl:ENSP00000328059	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:rnf12_human(display_long)|uniprotkb:RLIM(gene name)|psi-mi:RLIM(display_short)|uniprotkb:RNF12(gene name synonym)|uniprotkb:RING finger protein 12(gene name synonym)|uniprotkb:LIM domain-interacting RING finger protein(gene name synonym)|uniprotkb:RING finger LIM domain-binding protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-43(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RLIM(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341450|imex:IM-11696-471	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	refseq:NP_057204.2|refseq:NP_899196.1|ensembl:ENSG00000131263(gene)|ensembl:ENST00000332687(transcript)|ensembl:ENST00000349225(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060816"(random inactivation of X chromosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900095"(regulation of dosage compensation by inactivation of X chromosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NVW2|rcsb pdb:6W7Z|rcsb pdb:6W9A|rcsb pdb:6W9D|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:jEHiOt7hjZc5HU6E/XQGE7zdZbw9606	intact-crc:5C76AF2C6E7B510D|rigid:XgPdEQwv1tajjk8E6lYf8/hj2SM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6ZNA4	uniprotkb:Q96LR5	intact:EBI-2129175|uniprotkb:Q6ZMU2|uniprotkb:Q7L428|uniprotkb:Q7Z346|uniprotkb:Q8N1P9|uniprotkb:Q8WUA3|uniprotkb:Q9NSR1|uniprotkb:Q6P9A4|uniprotkb:C9JUS4|uniprotkb:H0YN55|ensembl:ENSP00000452732|intact:EBI-28970158	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:rn111_human(display_long)|uniprotkb:RNF111(gene name)|psi-mi:RNF111(display_short)|uniprotkb:RING finger protein 111(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Arkadia(gene name synonym)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341453|imex:IM-11696-472	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060080.6|ensembl:ENST00000348370|ensembl:ENSP00000288199|ensembl:ENSP00000452732|ensembl:ENST00000559209|ensembl:ENSP00000453872|ensembl:ENST00000561186|ensembl:ENSP00000453015|refseq:NP_001317260.1|refseq:XP_016877827.1|refseq:XP_006720642.1|refseq:NP_001257459.1|refseq:NP_001257457.1|refseq:NP_001257458.1|ensembl:ENSG00000157450(gene)|ensembl:ENST00000557998(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR029306|rcsb pdb:2KIZ|rcsb pdb:5LG0|rcsb pdb:5LG7|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-5696395|reactome:R-HSA-983168|go:"GO:0032184"(SUMO polymer binding)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:6SY5oMr5u4mnVi+zdRboVljMGa09606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:2DC25B3DC314C615|rigid:KIFGaI4S+/VfLi7VkLkjxlmXA1g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EQ8	uniprotkb:Q96LR5	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341456|imex:IM-11696-473	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:4D7200995618C1BD|rigid:gqXQ8qh4pbqCRDtbFUQajaJGEJo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EP1	uniprotkb:Q96LR5	intact:EBI-718923|uniprotkb:A6NEN5|uniprotkb:Q96SL3|uniprotkb:Q9NRT4|uniprotkb:Q9NT32|uniprotkb:Q9NVD5|uniprotkb:B4DZ77|uniprotkb:B4E2L6|ensembl:ENSP00000392395	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:chfr_human(display_long)|uniprotkb:Checkpoint with forkhead and RING finger domains protein(gene name synonym)|uniprotkb:RING finger protein 196(gene name synonym)|uniprotkb:CHFR(gene name)|psi-mi:CHFR(display_short)|uniprotkb:RNF196(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHFR(gene name synonym)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341459|imex:IM-11696-474	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154816.1|refseq:NP_001154817.1|refseq:NP_001154818.1|refseq:NP_001154819.1|refseq:NP_060693.2|ensembl:ENSG00000072609(gene)|ensembl:ENST00000432561(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR019406|interpro:IPR040909|rcsb pdb:1LGP|rcsb pdb:1LGQ|rcsb pdb:2XOC|rcsb pdb:2XOY|rcsb pdb:2XOZ|rcsb pdb:2XP0|dip:DIP-40098N	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid://FU72n6rmuPAu+Fjm377S4nEjw9606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:9591885E8D7575B6|rigid:ykyetrXTl8QGdh4mz/yuVUM+ebk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LR5	uniprotkb:Q8N9I9	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	intact:EBI-2340258|uniprotkb:Q8NDS8|uniprotkb:Q8NAU6|uniprotkb:Q53ZZ2|ensembl:ENSP00000338050|ensembl:ENSP00000447873|ensembl:ENSP00000449294	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:dtx3_human(display_long)|uniprotkb:DTX3(gene name)|psi-mi:DTX3(display_short)|uniprotkb:RNF154(gene name synonym)|uniprotkb:RING finger protein 154(gene name synonym)|uniprotkb:Protein deltex-3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341468|imex:IM-11696-477	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	refseq:NP_001273174.1|refseq:NP_001273175.1|refseq:XP_011536324.1|refseq:NP_848597.1|refseq:XP_005268754.1|refseq:XP_005268755.1|refseq:XP_005268757.1|refseq:XP_005268760.1|ensembl:ENSG00000178498(gene)|ensembl:ENST00000337737(transcript)|ensembl:ENST00000548198(transcript)|ensembl:ENST00000548804(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rogid:Ma7JBhgMdFofCeWESbf8h1iLAHY9606	intact-crc:30EC126A0307DD5C|rigid:NWzbrjH0gOHsARdVD+R11nvwJvo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86UD3	uniprotkb:Q96LR5	intact:EBI-2341065|uniprotkb:A8K264|uniprotkb:B9EJE7|ensembl:ENSP00000309141	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:marh3_human(display_long)|uniprotkb:MARCHF3(gene name)|psi-mi:MARCHF3(display_short)|uniprotkb:MARCH3(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 3(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein III(gene name synonym)|uniprotkb:RING finger protein 173(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF3(gene name synonym)|uniprotkb:RNF173(gene name synonym)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341462|imex:IM-11696-475	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_848545.1|ensembl:ENSG00000173926(gene)|ensembl:ENST00000308660(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:uv/JcWUoL549NACFaOUs/oLdHuI9606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:67B51BE1ECB269A4|rigid:NJCOZP+KvN3CDq/57AyaAogpLFo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96A37	uniprotkb:Q96LR5	intact:EBI-2130320|uniprotkb:B3KQ03|uniprotkb:Q96DM0|uniprotkb:D3DX75|uniprotkb:H3BTU8|ensembl:ENSP00000326095	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:rn166_human(display_long)|uniprotkb:RNF166(gene name)|psi-mi:RNF166(display_short)|uniprotkb:RING finger protein 166(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF166(gene name synonym)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341465|imex:IM-11696-476	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001165286.1|refseq:NP_001165287.1|refseq:NP_849163.1|refseq:XP_016878402.1|ensembl:ENSG00000158717(gene)|ensembl:ENST00000312838(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:QV195sbjVofHePvnO8nsleiWSkg9606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:43518AFC49757442|rigid:ta2kzhiXTzG6Wy5000q2PHbMhS4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:P36406	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341471|imex:IM-11696-478	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	intact-crc:514BCDCA2CCABA92|rigid:xtyYsGZk892/9jD8nbYaCT6vNDw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:O94972	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|ensembl:ENSP00000262294|ensembl:ENSP00000376785|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341474|imex:IM-11696-479	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_001005207.1|refseq:NP_056109.1|refseq:NP_001307916.1|ensembl:ENSP00000262294|ensembl:ENST00000393065|ensembl:ENSP00000376784|ensembl:ENSP00000376785|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070842"(aggresome assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|rcsb pdb:3LRQ|reactome:R-HSA-983168|ensembl:ENSG00000108395(gene)|ensembl:ENST00000262294(transcript)|ensembl:ENST00000393066(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035518"(histone H2A monoubiquitination)|refseq:NP_001307919.1|dip:DIP-34437N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606	intact-crc:D7CAE4A3C8EFA01C|rigid:YkSgarKm8svi818JN6KzJJum5uQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:Q9Y252	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-2341483|uniprotkb:Q9UF41|uniprotkb:Q5W0H0|uniprotkb:B4DDP0|uniprotkb:Q9BZP5|ensembl:ENSP00000342121|ensembl:ENSP00000370982|ensembl:ENSP00000371000	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:rnf6_human(display_long)|uniprotkb:RNF6(gene name)|psi-mi:RNF6(display_short)|uniprotkb:SPG2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341488|imex:IM-11696-200	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:XP_011533479.1|refseq:XP_011533480.1|refseq:NP_005968.1|refseq:NP_898864.1|refseq:NP_898865.1|refseq:NP_898866.1|refseq:XP_005266542.1|refseq:XP_005266543.1|ensembl:ENSG00000127870(gene)|ensembl:ENST00000346166(transcript)|ensembl:ENST00000381570(transcript)|ensembl:ENST00000381588(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030424"(axon)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:SDWFGC1UYHyNjerMH5quYDeKiQ49606	intact-crc:7EB21B1D5B0304D0|rigid:ExREIaQJVqTt7CXhobrA+URsnjA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:Q99496	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341477|imex:IM-11696-480	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	intact-crc:ADEF5A094B803BE9|rigid:jo8jDq0XqlxzYCyvLJ8Jaq6Srpo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:P78317	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-2340927|uniprotkb:Q49AR8|uniprotkb:B2R6D6|uniprotkb:D6RF58|intact:EBI-28970119|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:rnf4_human(display_long)|uniprotkb:SNURF(gene name synonym)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:RNF4(gene name)|psi-mi:RNF4(display_short)|uniprotkb:RES4-26(orf name)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341480|imex:IM-11696-199	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_001171938.1|refseq:NP_001171939.1|refseq:NP_002929.1|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503|ensembl:ENST00000511859|ensembl:ENSP00000426615|ensembl:ENST00000541204|ensembl:ENSP00000446369|ensembl:ENSG00000063978(gene)|ensembl:ENST00000314289(transcript)|ensembl:ENST00000506706(transcript)|ensembl:ENST00000511600(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|go:"GO:1990752"(microtubule end)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|mint:P78317|rcsb pdb:2EA6|rcsb pdb:2XEU|rcsb pdb:4PPE|reactome:R-HSA-5693607|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:Yhu2iAaNQYcfGdYohDPBdhMFEpc9606	intact-crc:BBCB0D08C2503AFF|rigid:IYtpdq9mCPhDGEPXI0yr+uP3/E4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:Q13064	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-2340269|ensembl:ENSP00000313881	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341491|imex:IM-11696-201	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606	intact-crc:B7CBC99900CCCFA4|rigid:8OKlOad7jAE4evhLMJyGY06VMAI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:Q7Z569	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-349900|uniprotkb:O43238|uniprotkb:O75341|ensembl:ENSP00000403524|uniprotkb:B9EGS8|uniprotkb:B4DRM1	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:brap_human(display_long)|uniprotkb:BRAP(gene name)|psi-mi:BRAP(display_short)|uniprotkb:RNF52(gene name synonym)|uniprotkb:BRAP2(gene name synonym)|uniprotkb:Impedes mitogenic signal propagation(gene name synonym)|uniprotkb:RING finger protein 52(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRAP2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341494|imex:IM-11696-202	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_006759.3|ensembl:ENSG00000089234(gene)|ensembl:ENST00000419234(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011422(BRCA1-associated 2)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034932|interpro:IPR035979|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-9649948	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:hk+0eh6wL1csHtwCgLqmX44QSVI9606	intact-crc:369F6516AFF944F1|rigid:zHQg9eWzTxiQ2z0tcIAHjqufBkY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BWF2	uniprotkb:P62256	intact:EBI-1756205|uniprotkb:O00467|uniprotkb:B5BU84|uniprotkb:B5BUL3|intact:EBI-28986477|ensembl:ENSP00000328203	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	psi-mi:traip_human(display_long)|uniprotkb:TRAIP(gene name)|psi-mi:TRAIP(display_short)|uniprotkb:RNF206(gene name synonym)|uniprotkb:TRIP(gene name synonym)|uniprotkb:RING finger protein 206(gene name synonym)|uniprotkb:TRAF-interacting protein(gene name synonym)	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341503|imex:IM-11696-205	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005870.2|ensembl:ENSP00000328203|ensembl:ENSG00000183763(gene)|ensembl:ENST00000331456(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007165"(signal transduction)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090734"(site of DNA damage)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:4ZTD|reactome:R-HSA-983168	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:af6osyzc1Cw/atmwUPTR1f5usBE9606	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	intact-crc:7FDE652AED36B9FB|rigid:0pxzHeSbmxGuuuR88extjEBPtgo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:P50876	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-2340657|uniprotkb:Q585H5|uniprotkb:D6W4Y6|ensembl:ENSP00000321330	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:r144a_human(display_long)|uniprotkb:RNF144A(gene name)|psi-mi:RNF144A(display_short)|uniprotkb:KIAA0161(gene name synonym)|uniprotkb:RNF144(gene name synonym)|uniprotkb:UBCE7IP4(gene name synonym)|uniprotkb:RING finger protein 144A(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 4(gene name synonym)|uniprotkb:UbcM4-interacting protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341497|imex:IM-11696-203	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_055561.2|refseq:XP_016860885.1|refseq:XP_005246257.1|refseq:XP_005246259.1|refseq:XP_016860886.1|ensembl:ENSG00000151692(gene)|ensembl:ENST00000320892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031127|interpro:IPR044066|mint:P50876|rcsb pdb:1WIM|rcsb pdb:6L99|reactome:R-HSA-8866654	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:i2Ls6RkN4dTdPkBoso7ZDyIqi+g9606	intact-crc:F67B39AF60C82A48|rigid:dM/UypAWkRb7ioF6B1AzV5SMlBo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5U6	uniprotkb:P62256	intact:EBI-714023|uniprotkb:Q92550|uniprotkb:Q9NPP8|uniprotkb:Q9ULW4|ensembl:ENSP00000322242	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	psi-mi:rnf10_human(display_long)|uniprotkb:RNF10(gene name)|psi-mi:RNF10(display_short)|uniprotkb:KIAA0262(gene name synonym)|uniprotkb:RIE2(gene name synonym)	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341500|imex:IM-11696-204	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055683.3|refseq:NP_001317403.1|ensembl:ENSG00000022840(gene)|ensembl:ENST00000325954(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039739|mint:Q8N5U6	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Bca0Ae456x1eCsdlduoCbn7coUQ9606	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	intact-crc:D5F6AC7C97C3B84A|rigid:ojDDeDm+DNpYdSqnwQu9kA67amE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:Q8WU17	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-1551681|uniprotkb:O75485|uniprotkb:Q7LDL3|uniprotkb:B3KMD5|ensembl:ENSP00000304051	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:rn139_human(display_long)|uniprotkb:Translocation in renal carcinoma on chromosome 8 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF139(gene name synonym)|uniprotkb:RING finger protein 139(gene name synonym)|uniprotkb:RNF139(gene name)|psi-mi:RNF139(display_short)|uniprotkb:TRC8(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341506|imex:IM-11696-206	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_009149.2|ensembl:ENSG00000170881(gene)|ensembl:ENST00000303545(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070613"(regulation of protein processing)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR025754|reactome:R-HSA-901032	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:LjH3X0GbTdHrU+hvPbJKZ3Bu9Jg9606	intact-crc:CAC81711742515C1|rigid:bU0C9U1P5WUS0pkIcD95sps8MQg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C040	uniprotkb:P62256	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341509|imex:IM-11696-207	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	intact-crc:EDBB4C962354CA03|rigid:4Wh2l1kyd1X1/MOavTkgmBqO4K4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:Q9ULV8	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-2341018|uniprotkb:Q9Y5Z3|uniprotkb:Q8N1E5|uniprotkb:Q9Y5Z2|intact:EBI-28975910|ensembl:ENSP00000494162	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:cblc_human(display_long)|uniprotkb:CBLC(gene name)|psi-mi:CBLC(display_short)|uniprotkb:CBL3(gene name synonym)|uniprotkb:RNF57(gene name synonym)|uniprotkb:SH3-binding protein CBL-C(gene name synonym)|uniprotkb:SH3-binding protein CBL-3(gene name synonym)|uniprotkb:RING finger protein 57(gene name synonym)|uniprotkb:Signal transduction protein CBL-C(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CBL-C(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341512|imex:IM-11696-208	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	ensembl:ENST00000341505|ensembl:ENSP00000340250|ensembl:ENSP00000494162|refseq:NP_001124324.1|refseq:NP_036248.3|ensembl:ENSG00000142273(gene)|ensembl:ENST00000647358(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|rcsb pdb:3OP0|rcsb pdb:3VRN|rcsb pdb:3VRO|rcsb pdb:3VRP|rcsb pdb:3VRQ|rcsb pdb:3VRR	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:syzTzR6RGJzLv2EpDirSrli4ghs9606	intact-crc:C8D07C0F29587982|rigid:9lboMV3Cbt9/Zle38kqApCAoTgk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y577	uniprotkb:P62256	intact:EBI-743894|uniprotkb:B4DVJ2|uniprotkb:Q5VST8|ensembl:ENSP00000295033|ensembl:ENSP00000355658|ensembl:ENSP00000355659|ensembl:ENSP00000493891|ensembl:ENSP00000495842|ensembl:ENSP00000496098	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	psi-mi:tri17_human(display_long)|uniprotkb:Testis RING finger protein(gene name synonym)|uniprotkb:RING finger protein 16(gene name synonym)|uniprotkb:TRIM17(gene name)|psi-mi:TRIM17(display_short)|uniprotkb:RBCC(gene name synonym)|uniprotkb:RNF16(gene name synonym)|uniprotkb:TERF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 17(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM17(gene name synonym)	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341515|imex:IM-11696-209	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162931(gene)|ensembl:ENSG00000285344(gene)|refseq:NP_001020111.1|refseq:NP_001128327.1|refseq:NP_057186.1|refseq:XP_011542511.1|refseq:XP_011542512.1|refseq:XP_006711842.1|ensembl:ENST00000295033(transcript)|ensembl:ENST00000366697(transcript)|ensembl:ENST00000366698(transcript)|ensembl:ENST00000645562(transcript)|ensembl:ENST00000645958(transcript)|ensembl:ENST00000647385(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045087"(innate immune response)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032918|interpro:IPR035687|interpro:IPR043136|reactome:R-HSA-877300	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pXiCDkeNMtq9icQduH4MSCM6vSQ9606	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	intact-crc:F8E25F191AF791F4|rigid:4G7A6eSxYTj4GvA0F6gitRbNyEA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:Q9NTX7	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-722397|uniprotkb:Q6FIB2|uniprotkb:Q7L8H4|uniprotkb:Q96K03|uniprotkb:Q9NTX6|uniprotkb:E1P572|uniprotkb:Q96T06|intact:EBI-28979460|ensembl:ENSP00000357297|ensembl:ENSP00000476814	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:rn146_human(display_long)|uniprotkb:Dactylidin(gene name synonym)|uniprotkb:RNF146(gene name)|psi-mi:RNF146(display_short)|uniprotkb:RING finger protein 146(gene name synonym)|uniprotkb:Iduna(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF146(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341529|imex:IM-11696-212	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_001229773.1|refseq:NP_001229774.1|refseq:NP_001229775.1|refseq:NP_001229778.1|refseq:NP_001229779.1|refseq:NP_001229780.1|refseq:NP_001229781.1|refseq:NP_112225.2|ensembl:ENSP00000357297|ensembl:ENST00000608991|ensembl:ENSP00000477168|ensembl:ENSP00000476814|refseq:NP_001229776.1|refseq:NP_001229777.1|refseq:XP_011534463.1|refseq:XP_011534464.1|refseq:XP_011534465.1|refseq:XP_011534466.1|refseq:XP_006715634.1|refseq:XP_016866825.1|refseq:XP_016866826.1|refseq:XP_016866827.1|refseq:XP_016866828.1|refseq:XP_016866829.1|refseq:XP_016866830.1|refseq:XP_016866831.1|refseq:XP_016866832.1|dip:DIP-52730N|ensembl:ENSG00000118518(gene)|ensembl:ENST00000368314(transcript)|ensembl:ENST00000610153(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0072572"(poly-ADP-D-ribose binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004170(WWE)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018123|interpro:IPR033509|interpro:IPR037197|interpro:IPR044110|mint:Q9NTX7|rcsb pdb:2D8T|rcsb pdb:3V3L|rcsb pdb:6CF6|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-5689880|reactome:R-HSA-8948751	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:7/KiZcZQYfSeZ6EYqP/FCtk1Mws9606	intact-crc:4B95DFA54479E7E0|rigid:Z+IuipykRpnWG7pfz6dkHVagsGI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NQ86	uniprotkb:P62256	intact:EBI-2341518|uniprotkb:Q0P5Z9|uniprotkb:A1L3Z1|uniprotkb:B7Z3V4|uniprotkb:B7ZAV7|uniprotkb:E9PFI8|uniprotkb:A6NDD0|ensembl:ENSP00000282369	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	psi-mi:tri36_human(display_long)|uniprotkb:TRIM36(gene name)|psi-mi:TRIM36(display_short)|uniprotkb:RBCC728(gene name synonym)|uniprotkb:RNF98(gene name synonym)|uniprotkb:Zinc-binding protein Rbcc728(gene name synonym)|uniprotkb:RING finger protein 98(gene name synonym)|uniprotkb:Tripartite motif-containing protein 36(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM36(gene name synonym)	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341523|imex:IM-11696-210	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061170.2|refseq:NP_001287681.1|refseq:NP_001287688.1|refseq:NP_001017397.1|refseq:NP_001017398.1|ensembl:ENSG00000152503(gene)|ensembl:ENST00000282369(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007051"(spindle organization)|go:"GO:0007340"(acrosome reaction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003879(Butyrophylin-like)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR027726|interpro:IPR035727|interpro:IPR036116|interpro:IPR040859|interpro:IPR043136|reactome:R-HSA-983168	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:+ex/otzq1H8m+SZ7ncFXlf9nyjs9606	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	intact-crc:B4F47EBF55B4E041|rigid:lPLNJSpnrHDRC03I6XHmBP1gKw8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:Q9Y508	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-723587|uniprotkb:Q6N0B0|uniprotkb:B2RDQ9|uniprotkb:B4DWY5|uniprotkb:E1P627|ensembl:ENSP00000244061	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:rn114_human(display_long)|uniprotkb:Zinc finger protein 313(gene name synonym)|uniprotkb:RNF114(gene name)|psi-mi:RNF114(display_short)|uniprotkb:ZNF313(gene name synonym)|uniprotkb:ZNF228(gene name synonym)|uniprotkb:Zinc finger protein 228(gene name synonym)|uniprotkb:RING finger protein 114(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF114(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341526|imex:IM-11696-211	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_061153.1|ensembl:ENSG00000124226(gene)|ensembl:ENST00000244061(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR034734|interpro:IPR042716|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:R1fX8xaGuIhy/M6cLzPeyfJBf649606	intact-crc:6A74232B8E5A6325|rigid:s4WFQkoorCcA+cmdw0+uKdZkFpQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C035	uniprotkb:P62256	intact:EBI-924214|uniprotkb:Q2MLV4|uniprotkb:Q2MLV8|uniprotkb:Q2MLV9|uniprotkb:Q2MLW1|uniprotkb:Q2MLW3|uniprotkb:Q2MLW4|uniprotkb:A6NGQ1|uniprotkb:Q2MLW6|uniprotkb:Q2MLW7|uniprotkb:Q2MLX1|uniprotkb:Q2MLX2|uniprotkb:Q2MLX3|uniprotkb:Q2MLX5|uniprotkb:Q2MLY3|uniprotkb:Q2MLY4|uniprotkb:Q2V6Q6|uniprotkb:Q6GX26|uniprotkb:Q8WU46|uniprotkb:Q96SR5|uniprotkb:Q9C031|uniprotkb:Q9C032|uniprotkb:Q9C033|uniprotkb:Q9C034|uniprotkb:A8WFA8|uniprotkb:D3DQS8|uniprotkb:D3DQS9|uniprotkb:G3GJY1|ensembl:ENSP00000369373|ensembl:ENSP00000507420	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	psi-mi:trim5_human(display_long)|uniprotkb:TRIM5(gene name)|psi-mi:TRIM5(display_short)|uniprotkb:RNF88(gene name synonym)|uniprotkb:RING finger protein 88(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM5(gene name synonym)	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341532|imex:IM-11696-213	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149023.2|refseq:NP_149083.2|refseq:NP_149084.2|refseq:XP_011518729.1|refseq:XP_005253240.1|refseq:XP_005253241.1|ensembl:ENSG00000132256(gene)|ensembl:ENST00000380034(transcript)|ensembl:ENST00000684655(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031664"(regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR043136|rcsb pdb:2ECV|rcsb pdb:2YRG|reactome:R-HSA-877300	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:t0YqhaJC8oQcwot7oks1LgMxdNc9606	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	intact-crc:2F893AE410939875|rigid:p0JjXviDjTOOKYzq4kxlekQQglQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:Q6UWE0	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-720984|uniprotkb:Q5VVV0|uniprotkb:Q8NB40|uniprotkb:Q96GT5|uniprotkb:Q96MX5|uniprotkb:Q96MZ7|ensembl:ENSP00000300417|ensembl:ENSP00000322937|ensembl:ENSP00000362419|ensembl:ENSP00000502167	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:lrsm1_human(display_long)|uniprotkb:Leucine-rich repeat and sterile alpha motif-containing protein 1(gene name synonym)|uniprotkb:Tsg101-associated ligase(gene name synonym)|uniprotkb:LRSAM1(gene name)|psi-mi:LRSAM1(display_short)|uniprotkb:TAL(gene name synonym)|uniprotkb:UNQ6496/PRO21356(orf name)|uniprotkb:RING-type E3 ubiquitin transferase LRSAM1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341535|imex:IM-11696-214	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_001005373.1|refseq:NP_001005374.1|refseq:NP_001177652.1|refseq:NP_612370.3|refseq:XP_016870772.1|ensembl:ENSG00000148356(gene)|ensembl:ENST00000300417(transcript)|ensembl:ENST00000323301(transcript)|ensembl:ENST00000373322(transcript)|ensembl:ENST00000675448(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0046755"(viral budding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032675|mint:Q6UWE0|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:qkwPqOsfNjZBB2Xp6YAA9FbEZxM9606	intact-crc:2599F26835AECE5F|rigid:qHDCQazZkuTPhxGmI9FjPGCSqVg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:Q96GF1	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-2340249|uniprotkb:A8K5C1|uniprotkb:A9X3T8|uniprotkb:Q8N900|ensembl:ENSP00000320508|ensembl:ENSP00000427755	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:rn185_human(display_long)|uniprotkb:RNF185(gene name)|psi-mi:RNF185(display_short)|uniprotkb:RING finger protein 185(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF185(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341538|imex:IM-11696-215	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_001129297.1|refseq:NP_689480.2|ensembl:ENSG00000138942(gene)|ensembl:ENST00000326132(transcript)|ensembl:ENST00000518626(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:ivzbt31KPTKL/Rc1Wzs3h80XJac9606	intact-crc:7C8EA44504A7FEF6|rigid:EZmRnADyCc0Ik4JE9Gg1wcCxBt8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96A37	uniprotkb:P62256	intact:EBI-2130320|uniprotkb:B3KQ03|uniprotkb:Q96DM0|uniprotkb:D3DX75|uniprotkb:H3BTU8|ensembl:ENSP00000326095	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	psi-mi:rn166_human(display_long)|uniprotkb:RNF166(gene name)|psi-mi:RNF166(display_short)|uniprotkb:RING finger protein 166(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF166(gene name synonym)	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341541|imex:IM-11696-216	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001165286.1|refseq:NP_001165287.1|refseq:NP_849163.1|refseq:XP_016878402.1|ensembl:ENSG00000158717(gene)|ensembl:ENST00000312838(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:QV195sbjVofHePvnO8nsleiWSkg9606	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	intact-crc:D191EFB1BAD6E3E7|rigid:4P8NM1gDJd66eQLjQBFdjc85BAE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:Q8IZP6	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-2340677|uniprotkb:Q96QY9|uniprotkb:Q8WWF9|ensembl:ENSP00000267291	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:r113b_human(display_long)|uniprotkb:RNF113B(gene name)|psi-mi:RNF113B(display_short)|uniprotkb:RNF161(gene name synonym)|uniprotkb:ZNF183L1(gene name synonym)|uniprotkb:Zinc finger protein 183-like 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341544|imex:IM-11696-217	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_849192.1|ensembl:ENSG00000139797(gene)|ensembl:ENST00000267291(transcript)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036855|interpro:IPR039971|rcsb pdb:2CSY	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:v4QnmiYlYp4zInfMBKQQxTUnrd89606	intact-crc:DCF0D8C523A6AF59|rigid:0kGjvEi1ciaOQtgogqPabIXGFK0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:Q9H0F5	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-2341200|uniprotkb:Q8N0Y0|uniprotkb:A6PVP9|uniprotkb:B1AM82|uniprotkb:Q7LB33|ensembl:ENSP00000259605|uniprotkb:B1AM81|uniprotkb:B3KSG4|uniprotkb:E7EVL3|uniprotkb:Q9H748	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:rnf38_human(display_long)|uniprotkb:RING finger protein 38(gene name synonym)|uniprotkb:RNF38(gene name)|psi-mi:RNF38(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF38(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341550|imex:IM-11696-219	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:XP_011516014.1|refseq:XP_011516015.1|refseq:XP_006716784.1|refseq:NP_073618.3|refseq:NP_919309.1|refseq:NP_919310.1|refseq:NP_919311.1|refseq:NP_919313.1|ensembl:ENSG00000137075(gene)|ensembl:ENST00000259605(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008584"(male gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|go:"GO:0036126"(sperm flagellum)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9H0F5|rcsb pdb:1X4J|rcsb pdb:4V3K|rcsb pdb:4V3L|ensembl:ENSP00000259605|ensembl:ENST00000350199|ensembl:ENSP00000343947|ensembl:ENST00000353739|ensembl:ENSP00000335239|ensembl:ENST00000357058|ensembl:ENSP00000349566|ensembl:ENST00000377877|ensembl:ENSP00000367109|ensembl:ENST00000377885|ensembl:ENSP00000367117|ensembl:ENST00000611646|ensembl:ENSP00000483536|refseq:XP_005251423.1|refseq:XP_005251424.1|refseq:XP_005251425.1|refseq:XP_016869784.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:leJgsTFAtsRhHPh44pbrpk1wkDo9606	intact-crc:8C09B953815A9897|rigid:A1h+gEIvI/GS45xuKTUmOBKjst8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:Q8TDB6	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-2340392|uniprotkb:Q5MJP7|uniprotkb:Q53ZZ3|uniprotkb:B3KWH6|ensembl:ENSP00000296161	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:dtx3l_human(display_long)|uniprotkb:DTX3L(gene name)|psi-mi:DTX3L(display_short)|uniprotkb:BBAP(gene name synonym)|uniprotkb:B-lymphoma- and BAL-associated protein(gene name synonym)|uniprotkb:Rhysin-2(gene name synonym)|uniprotkb:Protein deltex-3-like(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3L(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341547|imex:IM-11696-218	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_612144.1|ensembl:ENSG00000163840(gene)|ensembl:ENST00000296161(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0015031"(protein transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:2000646"(positive regulation of receptor catabolic process)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|interpro:IPR042843|rcsb pdb:3PG6|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:d2ctDfd7pj1wRA3HxmyWJ5nL19Y9606	intact-crc:5F6120E5A1A96BE0|rigid:/titqqU73w681cKyWYWwL9f5ghM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WVZ7	uniprotkb:P62256	intact:EBI-2341563|uniprotkb:Q8N7G7|uniprotkb:A4D0W2|ensembl:ENSP00000344489	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	psi-mi:rn133_human(display_long)|uniprotkb:RNF133(gene name)|psi-mi:RNF133(display_short)|uniprotkb:RING finger protein 133(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF133(gene name synonym)	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341562|imex:IM-11696-221	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_631914.1|ensembl:ENSG00000188050(gene)|ensembl:ENST00000340112(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:TAMciq1QvlCXIYvKwzdzmj34P109606	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	intact-crc:AE0069696C447B19|rigid:oAee/ypkzry6THwdkmMYpqz3g34	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NA82	uniprotkb:P62256	intact:EBI-2341554|uniprotkb:D3DU09|uniprotkb:Q8N7Z7|uniprotkb:Q8IYS7|ensembl:ENSP00000311496|ensembl:ENSP00000416177	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	psi-mi:marha_human(display_long)|uniprotkb:MARCHF10(gene name)|psi-mi:MARCHF10(display_short)|uniprotkb:MARCH10(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 10(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein X(gene name synonym)|uniprotkb:RING finger protein 190(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF10(gene name synonym)|uniprotkb:RNF190(gene name synonym)	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341553|imex:IM-11696-220	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094345.1|refseq:NP_689811.2|refseq:NP_001275708.1|refseq:NP_001275709.1|ensembl:ENSG00000173838(gene)|ensembl:ENST00000311269(transcript)|ensembl:ENST00000456609(transcript)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042583	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xYNhVYIVxXneNrLbdaSO0uTK9l89606	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	intact-crc:FEAC7A2E0CCBACB3|rigid:8m5KlsSzlb7o/BwT6zcDvBWKgjE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36406	uniprotkb:P63279	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341573|imex:IM-11696-223	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:1656F85D889F5D03|rigid:ChUy9DmEZ8IqsrUWZ3GiEhdqx+E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62256	uniprotkb:Q8N9I9	intact:EBI-2129909|uniprotkb:P37286|uniprotkb:A4D1L6|uniprotkb:C9JY93|uniprotkb:Q7Z6F4|ensembl:ENSP00000347836	intact:EBI-2340258|uniprotkb:Q8NDS8|uniprotkb:Q8NAU6|uniprotkb:Q53ZZ2|ensembl:ENSP00000338050|ensembl:ENSP00000447873|ensembl:ENSP00000449294	psi-mi:ube2h_human(display_long)|uniprotkb:UBE2H(gene name)|psi-mi:UBE2H(display_short)|uniprotkb:Ubiquitin-protein ligase H(gene name synonym)|uniprotkb:Ubiquitin carrier protein H(gene name synonym)|uniprotkb:UbcH2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-20K(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme H"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme H(gene name synonym)	psi-mi:dtx3_human(display_long)|uniprotkb:DTX3(gene name)|psi-mi:DTX3(display_short)|uniprotkb:RNF154(gene name synonym)|uniprotkb:RING finger protein 154(gene name synonym)|uniprotkb:Protein deltex-3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341570|imex:IM-11696-222	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189427.1|refseq:NP_003335.1|refseq:NP_874356.1|ensembl:ENSG00000186591(gene)|ensembl:ENST00000355621(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Z5D|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_001273174.1|refseq:NP_001273175.1|refseq:XP_011536324.1|refseq:NP_848597.1|refseq:XP_005268754.1|refseq:XP_005268755.1|refseq:XP_005268757.1|refseq:XP_005268760.1|ensembl:ENSG00000178498(gene)|ensembl:ENST00000337737(transcript)|ensembl:ENST00000548198(transcript)|ensembl:ENST00000548804(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hNy9GrFWU6iHxt0qjop7unBnlWQ9606	rogid:Ma7JBhgMdFofCeWESbf8h1iLAHY9606	intact-crc:9832EE9211548599|rigid:dzizcl4N/Elf39A2UrIuhPmXuLI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P35226	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341582|imex:IM-11696-224	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606	intact-crc:595CCBD23CD730B5|rigid:02kRCL18Y6zPTNoARvQILAp+HkQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:O60683	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-594789|uniprotkb:Q5T095|uniprotkb:Q9BW90|uniprotkb:B3KWD8|ensembl:ENSP00000407922	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:pex10_human(display_long)|uniprotkb:Peroxisome assembly protein 10(gene name synonym)|uniprotkb:RING finger protein 69(gene name synonym)|uniprotkb:PEX10(gene name)|psi-mi:PEX10(display_short)|uniprotkb:RNF69(gene name synonym)|uniprotkb:Peroxin-10(gene name synonym)|uniprotkb:Peroxisomal biogenesis factor 10(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341585|imex:IM-11696-225	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_002608.1|refseq:NP_722540.1|ensembl:ENSG00000157911(gene)|ensembl:ENST00000447513(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-8866654|reactome:R-HSA-9033241|interpro:IPR006845(Pex, N-terminal)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:PvnX5BURj5+GWmufgiODv7NWc8M9606	intact-crc:53ECA5D1C27E43B3|rigid:Xibo7d9WhauKNwK0mjPTBg1UjbQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q13064	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-2340269|ensembl:ENSP00000313881	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341594|imex:IM-11696-228	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606	intact-crc:4F2834D1AA66A122|rigid:lgtpks1EF+2qJvO16vQsd1l4ciI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P14373	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341588|imex:IM-11696-226	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:2FF0CE3FDF9ED3A4|rigid:fZxLnXJ+Vao7kidbG04rfSEKrG8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P78317	uniprotkb:P63279	intact:EBI-2340927|uniprotkb:Q49AR8|uniprotkb:B2R6D6|uniprotkb:D6RF58|intact:EBI-28970119|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:rnf4_human(display_long)|uniprotkb:SNURF(gene name synonym)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:RNF4(gene name)|psi-mi:RNF4(display_short)|uniprotkb:RES4-26(orf name)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341591|imex:IM-11696-227	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171938.1|refseq:NP_001171939.1|refseq:NP_002929.1|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503|ensembl:ENST00000511859|ensembl:ENSP00000426615|ensembl:ENST00000541204|ensembl:ENSP00000446369|ensembl:ENSG00000063978(gene)|ensembl:ENST00000314289(transcript)|ensembl:ENST00000506706(transcript)|ensembl:ENST00000511600(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|go:"GO:1990752"(microtubule end)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|mint:P78317|rcsb pdb:2EA6|rcsb pdb:2XEU|rcsb pdb:4PPE|reactome:R-HSA-5693607|reactome:R-HSA-983168	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Yhu2iAaNQYcfGdYohDPBdhMFEpc9606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:4328F04068FA5479|rigid:DF603Xyl0V0Hz3s9ohGVzbggMlk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q86Y13	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341597|imex:IM-11696-229	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:8CB737BA5422F03B|rigid:brHWCcMOPCZp3VGEYCzxQ45U6zs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:O60291	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-2129851|uniprotkb:A4URL3|uniprotkb:A4URL4|uniprotkb:Q86W76|intact:EBI-28986785|ensembl:ENSP00000382487	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:mgrn1_human(display_long)|uniprotkb:MGRN1(gene name)|psi-mi:MGRN1(display_short)|uniprotkb:KIAA0544(gene name synonym)|uniprotkb:RNF156(gene name synonym)|uniprotkb:Mahogunin RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 156(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MGRN1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341600|imex:IM-11696-230	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_001135761.2|refseq:NP_001135762.1|refseq:NP_001135763.2|refseq:NP_056061.1|ensembl:ENST00000262370|ensembl:ENSP00000262370|ensembl:ENSP00000382487|ensembl:ENST00000415496|ensembl:ENSP00000393311|ensembl:ENST00000586183|ensembl:ENSP00000465860|ensembl:ENST00000588994|ensembl:ENSP00000468819|refseq:XP_005255277.1|refseq:XP_005255278.1|ensembl:ENSG00000102858(gene)|ensembl:ENST00000399577(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:UuLoCnlkpTBs/rmGgpQvgiMNuNE9606	intact-crc:4DCF2A67DD13F5C8|rigid:enRYp/D38MDlcaFbczi3xL8UCa4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9ULV8	uniprotkb:P63279	intact:EBI-2341018|uniprotkb:Q9Y5Z3|uniprotkb:Q8N1E5|uniprotkb:Q9Y5Z2|intact:EBI-28975910|ensembl:ENSP00000494162	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:cblc_human(display_long)|uniprotkb:CBLC(gene name)|psi-mi:CBLC(display_short)|uniprotkb:CBL3(gene name synonym)|uniprotkb:RNF57(gene name synonym)|uniprotkb:SH3-binding protein CBL-C(gene name synonym)|uniprotkb:SH3-binding protein CBL-3(gene name synonym)|uniprotkb:RING finger protein 57(gene name synonym)|uniprotkb:Signal transduction protein CBL-C(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CBL-C(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341603|imex:IM-11696-231	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000341505|ensembl:ENSP00000340250|ensembl:ENSP00000494162|refseq:NP_001124324.1|refseq:NP_036248.3|ensembl:ENSG00000142273(gene)|ensembl:ENST00000647358(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|rcsb pdb:3OP0|rcsb pdb:3VRN|rcsb pdb:3VRO|rcsb pdb:3VRP|rcsb pdb:3VRQ|rcsb pdb:3VRR	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:syzTzR6RGJzLv2EpDirSrli4ghs9606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:3033814783F21704|rigid:WSarskzfmn3/LxutmImJVy3OrFA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q9HBD1	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-2340719|uniprotkb:Q8N3D6|uniprotkb:Q9H5J2|uniprotkb:Q9NWN9|uniprotkb:Q9NXE1|uniprotkb:Q86ST6|uniprotkb:Q5JPD7|uniprotkb:Q9HBD2|uniprotkb:Q96F27|uniprotkb:Q4VXB1|ensembl:ENSP00000349783|ensembl:ENSP00000362774	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:rc3h2_human(display_long)|uniprotkb:RC3H2(gene name)|psi-mi:RC3H2(display_short)|uniprotkb:MNAB(gene name synonym)|uniprotkb:RNF164(gene name synonym)|uniprotkb:Membrane-associated nucleic acid-binding protein(gene name synonym)|uniprotkb:RING finger protein 164(gene name synonym)|uniprotkb:RING finger and CCCH-type zinc finger domain-containing protein 2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Roquin-2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341606|imex:IM-11696-232	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_001094058.1|refseq:NP_061323.2|ensembl:ENSG00000056586(gene)|ensembl:ENST00000357244(transcript)|ensembl:ENST00000373670(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009986"(cell surface)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0046872"(metal ion binding)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060173"(limb development)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032670|interpro:IPR036855|interpro:IPR041523|rcsb pdb:4Z30|rcsb pdb:4Z31|rcsb pdb:4ZLC|rcsb pdb:4ZLD	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:UThBG9DsQJ7jfnx9xkCBkBKkaT89606	intact-crc:C28D8ECD2DFAB16F|rigid:qumiL0LH3QfCHCCBMelzHpqFPYQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q9NX47	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-2341610|ensembl:ENSP00000351813	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:marh5_human(display_long)|uniprotkb:MARCH5(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 5(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein V(gene name synonym)|uniprotkb:Mitochondrial ubiquitin ligase(gene name synonym)|uniprotkb:RING finger protein 153(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF5(gene name synonym)|uniprotkb:MARCHF5(gene name)|psi-mi:MARCHF5(display_short)|uniprotkb:RNF153(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341609|imex:IM-11696-233	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_060294.1|ensembl:ENSG00000198060(gene)|ensembl:ENST00000358935(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051020"(GTPase binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090344"(negative regulation of cell aging)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NX47	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:/w+L/oINlKM5ZSm1OkI+R+8PxXg9606	intact-crc:7C414F3199A01144|rigid:z6Nn7BMV+z88N42eafVg7SL3iVA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NS91	uniprotkb:P63279	intact:EBI-2339393|uniprotkb:Q9NRT6|uniprotkb:Q58F55|ensembl:ENSP00000264926	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:rad18_human(display_long)|uniprotkb:RAD18(gene name)|psi-mi:RAD18(display_short)|uniprotkb:RNF73(gene name synonym)|uniprotkb:Postreplication repair protein RAD18(gene name synonym)|uniprotkb:RING finger protein 73(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RAD18(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341616|imex:IM-11696-234	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064550.3|ensembl:ENSP00000264926|dip:DIP-29831N|ensembl:ENSG00000070950(gene)|ensembl:ENST00000264926(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097505"(Rad6-Rad18 complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036361|interpro:IPR039577|mint:Q9NS91|rcsb pdb:2MRE|rcsb pdb:2MRF|rcsb pdb:2Y43|rcsb pdb:2YBF|rcsb pdb:5VF0|reactome:R-HSA-110314|reactome:R-HSA-8866654|go:"GO:0060548"(negative regulation of cell death)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:/HmKCLqG1BxzmIWCgVpOw/gzJc49606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:81F3811D7A4C51ED|rigid:GUkibCGVYUA/VAkmop8DPqdRnSg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q8TEB7	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-2341619|uniprotkb:Q6ZTJ8|uniprotkb:Q9H5E4|uniprotkb:Q96RF3|uniprotkb:Q6PH80|uniprotkb:A0PJI4|ensembl:ENSP00000255499	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:rn128_human(display_long)|uniprotkb:RNF128(gene name)|psi-mi:RNF128(display_short)|uniprotkb:RING finger protein 128(gene name synonym)|uniprotkb:Gene related to anergy in lymphocytes protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF128(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341627|imex:IM-11696-235	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_078815.3|refseq:NP_919445.1|ensembl:ENSG00000133135(gene)|ensembl:ENST00000255499(transcript)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1904352"(positive regulation of protein catabolic process in the vacuole)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:3ICU|reactome:R-HSA-5689880|reactome:R-HSA-5689896	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:rHG5hoB/R1yW2BDsMr7LJEAXAWw9606	intact-crc:1C89D61DB078AF07|rigid:P0IJNmAdEPQ21wAcazR88ftXlEI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q8WV44	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-725997|uniprotkb:Q5BKT0|uniprotkb:Q7L484|uniprotkb:Q96Q10|intact:EBI-1551110|uniprotkb:Q9BSL8|uniprotkb:B3KNJ6|uniprotkb:D3DWR9|ensembl:ENSP00000320869	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:tri41_human(display_long)|uniprotkb:TRIM41(gene name)|psi-mi:TRIM41(display_short)|uniprotkb:RINCK(gene name synonym)|uniprotkb:Tripartite motif-containing protein 41(gene name synonym)|uniprotkb:RING finger-interacting protein with C kinase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM41(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341630|imex:IM-11696-236	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_291027.3|refseq:NP_963921.1|ensembl:ENSG00000146063(gene)|ensembl:ENST00000315073(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042828|interpro:IPR043136|mint:Q8WV44|rcsb pdb:2EGM|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:BVqf0OHXPGsYe8F66mHzvD4XQ549606	intact-crc:3A16A48D335030B5|rigid:Fz9pl3T1/wzw754be6HEQCJxbCQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q8WVZ7	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-2341563|uniprotkb:Q8N7G7|uniprotkb:A4D0W2|ensembl:ENSP00000344489	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:rn133_human(display_long)|uniprotkb:RNF133(gene name)|psi-mi:RNF133(display_short)|uniprotkb:RING finger protein 133(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF133(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341639|imex:IM-11696-239	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_631914.1|ensembl:ENSG00000188050(gene)|ensembl:ENST00000340112(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:TAMciq1QvlCXIYvKwzdzmj34P109606	intact-crc:56E39421C6EE159F|rigid:N0D5Ifl4HzfMmAbixdK21eg0Qhk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96GF1	uniprotkb:P63279	intact:EBI-2340249|uniprotkb:A8K5C1|uniprotkb:A9X3T8|uniprotkb:Q8N900|ensembl:ENSP00000320508|ensembl:ENSP00000427755	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:rn185_human(display_long)|uniprotkb:RNF185(gene name)|psi-mi:RNF185(display_short)|uniprotkb:RING finger protein 185(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF185(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341633|imex:IM-11696-237	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001129297.1|refseq:NP_689480.2|ensembl:ENSG00000138942(gene)|ensembl:ENST00000326132(transcript)|ensembl:ENST00000518626(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ivzbt31KPTKL/Rc1Wzs3h80XJac9606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:846D590DAE0D9070|rigid:4C70GPenaxoOcFqh3ZN36BjYFco	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TDB6	uniprotkb:P63279	intact:EBI-2340392|uniprotkb:Q5MJP7|uniprotkb:Q53ZZ3|uniprotkb:B3KWH6|ensembl:ENSP00000296161	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:dtx3l_human(display_long)|uniprotkb:DTX3L(gene name)|psi-mi:DTX3L(display_short)|uniprotkb:BBAP(gene name synonym)|uniprotkb:B-lymphoma- and BAL-associated protein(gene name synonym)|uniprotkb:Rhysin-2(gene name synonym)|uniprotkb:Protein deltex-3-like(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3L(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341636|imex:IM-11696-238	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612144.1|ensembl:ENSG00000163840(gene)|ensembl:ENST00000296161(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0015031"(protein transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:2000646"(positive regulation of receptor catabolic process)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|interpro:IPR042843|rcsb pdb:3PG6|reactome:R-HSA-983168	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:d2ctDfd7pj1wRA3HxmyWJ5nL19Y9606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:A782DDAD0B030566|rigid:vMZumYdRl2bhVUK8FdXRqBTZg1k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q6ZMU5	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-2341648|uniprotkb:Q8NBD9|uniprotkb:Q8N4X6|ensembl:ENSP00000312675	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:tri72_human(display_long)|uniprotkb:MG53(gene name synonym)|uniprotkb:Mitsugumin-53(gene name synonym)|uniprotkb:TRIM72(gene name)|psi-mi:TRIM72(display_short)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341654|imex:IM-11696-242	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_001008275.2|ensembl:ENSG00000177238(gene)|ensembl:ENST00000322122(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003012"(muscle system process)|go:"GO:0005737"(cytoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043569"(negative regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035038|interpro:IPR043136|rcsb pdb:3KB5|reactome:R-HSA-445355	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:VCAJhhHVyj0IGu2fej48PhXGJIU9606	intact-crc:6E70DE748BF28104|rigid:sdLcNW4pJv2bL0d5o0sZayJAIm8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N448	uniprotkb:P63279	intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341642|imex:IM-11696-240	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:cIS5t4XkbnIgelDlUc692nI285g9606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:054C6FA7D6EBB94D|rigid:gViC/5cVAJrFUzhIrAIBk8XOgs8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z419	uniprotkb:P63279	intact:EBI-2129982|uniprotkb:B3KUA8|uniprotkb:Q5TB85|uniprotkb:Q6P4Q0|uniprotkb:Q8N3R7|uniprotkb:Q9BX38|uniprotkb:B4DZI2|ensembl:ENSP00000259939	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:r144b_human(display_long)|uniprotkb:RNF144B(gene name)|psi-mi:RNF144B(display_short)|uniprotkb:IBRDC2(gene name synonym)|uniprotkb:P53RFP(gene name synonym)|uniprotkb:RING finger protein 144B(gene name synonym)|uniprotkb:IBR domain-containing protein 2(gene name synonym)|uniprotkb:p53-inducible RING finger protein(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341645|imex:IM-11696-241	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_877434.2|dip:DIP-43771N|ensembl:ENSG00000137393(gene)|ensembl:ENST00000259939(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Ep53jYpmEeClpBZYNkPKrQgy/0A9606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:07074B1CCE813889|rigid:HEmi+TwJ1wvOEoSBBJ6+zAhPJUE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P68036	uniprotkb:O15344	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	intact:EBI-2340316|uniprotkb:Q9BZX5|uniprotkb:O75361|uniprotkb:B2RCG2|ensembl:ENSP00000312678|ensembl:ENSP00000370156|ensembl:ENSP00000370157|ensembl:ENSP00000370162|ensembl:ENSP00000370164|ensembl:ENSP00000414521	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:tri18_human(display_long)|uniprotkb:MID1(gene name)|psi-mi:MID1(display_short)|uniprotkb:FXY(gene name synonym)|uniprotkb:RNF59(gene name synonym)|uniprotkb:TRIM18(gene name synonym)|uniprotkb:XPRF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 18(gene name synonym)|uniprotkb:Putative transcription factor XPRF(gene name synonym)|uniprotkb:Midin(gene name synonym)|uniprotkb:RING finger protein 59(gene name synonym)|uniprotkb:RING finger protein Midline-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Midline-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341657|imex:IM-11696-243	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	refseq:NP_000372.1|refseq:NP_001092094.1|refseq:NP_001180206.1|refseq:NP_001180207.1|refseq:NP_001180208.1|refseq:NP_001180209.1|refseq:NP_001180210.1|refseq:NP_150632.1|refseq:NP_001334662.1|refseq:XP_016885025.1|refseq:XP_016885029.1|ensembl:ENSG00000101871(gene)|ensembl:ENST00000317552(transcript)|ensembl:ENST00000380779(transcript)|ensembl:ENST00000380780(transcript)|ensembl:ENST00000380785(transcript)|ensembl:ENST00000380787(transcript)|ensembl:ENST00000453318(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016740"(transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003649(B-box, C-terminal)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR027727|interpro:IPR036116|interpro:IPR040859|interpro:IPR043136|rcsb pdb:2DQ5|rcsb pdb:2FFW|rcsb pdb:2JUN|rcsb pdb:5IM8|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	rogid:NGlMGyFT7GEcrzVR/Iw4LitMBig9606	intact-crc:2F658061D8E34A1E|rigid:Ag+cT1D5OBHY0o8km97hoAQYoM4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13064	uniprotkb:P68036	intact:EBI-2340269|ensembl:ENSP00000313881	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym)	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341660|imex:IM-11696-244	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	intact-crc:356F833139A6CFA5|rigid:lO1d6myGbwccHm602XNYysOLcms	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9ULV8	uniprotkb:P68036	intact:EBI-2341018|uniprotkb:Q9Y5Z3|uniprotkb:Q8N1E5|uniprotkb:Q9Y5Z2|intact:EBI-28975910|ensembl:ENSP00000494162	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	psi-mi:cblc_human(display_long)|uniprotkb:CBLC(gene name)|psi-mi:CBLC(display_short)|uniprotkb:CBL3(gene name synonym)|uniprotkb:RNF57(gene name synonym)|uniprotkb:SH3-binding protein CBL-C(gene name synonym)|uniprotkb:SH3-binding protein CBL-3(gene name synonym)|uniprotkb:RING finger protein 57(gene name synonym)|uniprotkb:Signal transduction protein CBL-C(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CBL-C(gene name synonym)	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341663|imex:IM-11696-245	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000341505|ensembl:ENSP00000340250|ensembl:ENSP00000494162|refseq:NP_001124324.1|refseq:NP_036248.3|ensembl:ENSG00000142273(gene)|ensembl:ENST00000647358(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|rcsb pdb:3OP0|rcsb pdb:3VRN|rcsb pdb:3VRO|rcsb pdb:3VRP|rcsb pdb:3VRQ|rcsb pdb:3VRR	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:syzTzR6RGJzLv2EpDirSrli4ghs9606	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	intact-crc:4A7436A710327983|rigid:vvIAXJZXORVjIMRG+ojJIGAdnCI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCM9	uniprotkb:P68036	intact:EBI-739510|uniprotkb:Q5STG4|uniprotkb:Q76BL3|uniprotkb:Q8IYT9|uniprotkb:Q96IB6|ensembl:ENSP00000365844|ensembl:ENSP00000373096|ensembl:ENSP00000379796|ensembl:ENSP00000391917|ensembl:ENSP00000397043|ensembl:ENSP00000398355|ensembl:ENSP00000409902|ensembl:ENSP00000411949|ensembl:ENSP00000447835|ensembl:ENSP00000448462|ensembl:ENSP00000448572|ensembl:ENSP00000449272|ensembl:ENSP00000449847|ensembl:ENSP00000450288|uniprotkb:Q5STG3	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	psi-mi:tri39_human(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341666|imex:IM-11696-246	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376656(transcript)|ensembl:ENST00000383602(transcript)|ensembl:ENST00000396547(transcript)|ensembl:ENST00000413715(transcript)|ensembl:ENST00000424575(transcript)|ensembl:ENST00000445206(transcript)|ensembl:ENST00000426469(transcript)|ensembl:ENST00000451715(transcript)|ensembl:ENST00000547030(transcript)|ensembl:ENST00000548002(transcript)|ensembl:ENST00000549841(transcript)|ensembl:ENST00000550282(transcript)|ensembl:ENST00000552337(transcript)|ensembl:ENST00000552520(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035033|interpro:IPR043136|mint:Q9HCM9|rcsb pdb:2DID|rcsb pdb:2DIF|rcsb pdb:2ECJ|reactome:R-HSA-983168|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_067076.2|refseq:NP_742013.1	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xMCXGcMTqCjzLQzC53o81S4gqZA9606	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	intact-crc:C5F451CB33D11C8F|rigid:1SstUevFp3qM9g9j/M+bOdwDesk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKV5	uniprotkb:P61088	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341675|imex:IM-11696-249	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	intact-crc:63F10A9649BB299E|rigid:ZJOpLHSmXfoEySCmPCZHWPuRaME	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P68036	uniprotkb:Q6Q0C0	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	intact:EBI-307556|uniprotkb:Q9H073|ensembl:ENSP00000318944	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:traf7_human(display_long)|uniprotkb:TRAF7(gene name)|psi-mi:TRAF7(display_short)|uniprotkb:TNF receptor-associated factor 7(gene name synonym)|uniprotkb:RING finger and WD repeat-containing protein 1(gene name synonym)|uniprotkb:RING finger protein 119(gene name synonym)|uniprotkb:RFWD1(gene name synonym)|uniprotkb:RNF119(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341669|imex:IM-11696-247	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	refseq:NP_115647.2|ensembl:ENSG00000131653(gene)|ensembl:ENST00000326181(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017907|interpro:IPR019775|interpro:IPR020472|interpro:IPR027370|interpro:IPR036322|mint:Q6Q0C0|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	rogid:46dtsS1OairncB0fnINSW1aY2789606	intact-crc:EBFBD1E0346CD36E|rigid:V1NuTmVqVogvwljnTFo5KburBbM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N9I9	uniprotkb:P68036	intact:EBI-2340258|uniprotkb:Q8NDS8|uniprotkb:Q8NAU6|uniprotkb:Q53ZZ2|ensembl:ENSP00000338050|ensembl:ENSP00000447873|ensembl:ENSP00000449294	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	psi-mi:dtx3_human(display_long)|uniprotkb:DTX3(gene name)|psi-mi:DTX3(display_short)|uniprotkb:RNF154(gene name synonym)|uniprotkb:RING finger protein 154(gene name synonym)|uniprotkb:Protein deltex-3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3(gene name synonym)	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341672|imex:IM-11696-248	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273174.1|refseq:NP_001273175.1|refseq:XP_011536324.1|refseq:NP_848597.1|refseq:XP_005268754.1|refseq:XP_005268755.1|refseq:XP_005268757.1|refseq:XP_005268760.1|ensembl:ENSG00000178498(gene)|ensembl:ENST00000337737(transcript)|ensembl:ENST00000548198(transcript)|ensembl:ENST00000548804(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Ma7JBhgMdFofCeWESbf8h1iLAHY9606	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	intact-crc:1A96A43A283E8598|rigid:R7obQrTcECTlPqUemyl/mlzNQG8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14258	uniprotkb:P61088	intact:EBI-2341129|intact:EBI-28973868|ensembl:ENSP00000323889|ensembl:ENSP00000445961	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	psi-mi:tri25_human(display_long)|uniprotkb:TRIM25(gene name)|psi-mi:TRIM25(display_short)|uniprotkb:EFP(gene name synonym)|uniprotkb:RNF147(gene name synonym)|uniprotkb:ZNF147(gene name synonym)|uniprotkb:Zinc finger protein 147(gene name synonym)|uniprotkb:Estrogen-responsive finger protein(gene name synonym)|uniprotkb:RING finger protein 147(gene name synonym)|uniprotkb:Ubiquitin/ISG15-conjugating enzyme TRIM25(gene name synonym)|uniprotkb:Tripartite motif-containing protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM25(gene name synonym)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341678|imex:IM-11696-250	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000323889|ensembl:ENSP00000445961|refseq:NP_005073.2|ensembl:ENSG00000121060(gene)|ensembl:ENST00000316881(transcript)|ensembl:ENST00000537230(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016604"(nuclear body)|go:"GO:0016874"(ligase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033280"(response to vitamin D)|go:"GO:0039552"(RIG-I binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043627"(response to estrogen)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|go:"GO:1902187"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042753|interpro:IPR043136|mint:Q14258|rcsb pdb:4CFG|rcsb pdb:4LTB|rcsb pdb:5EYA|rcsb pdb:5FER|rcsb pdb:5NT1|rcsb pdb:5NT2|rcsb pdb:6FLM|rcsb pdb:6FLN|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-5689896|reactome:R-HSA-877300|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:NhFfC0IxHvxPIt2YnKCPsPKuiQA9606	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	intact-crc:E7403E857114B341|rigid:bomilYL480rkwMmI2VZfjfMf+T8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q9NX47	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-2341610|ensembl:ENSP00000351813	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:marh5_human(display_long)|uniprotkb:MARCH5(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 5(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein V(gene name synonym)|uniprotkb:Mitochondrial ubiquitin ligase(gene name synonym)|uniprotkb:RING finger protein 153(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF5(gene name synonym)|uniprotkb:MARCHF5(gene name)|psi-mi:MARCHF5(display_short)|uniprotkb:RNF153(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341681|imex:IM-11696-251	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	refseq:NP_060294.1|ensembl:ENSG00000198060(gene)|ensembl:ENST00000358935(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051020"(GTPase binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090344"(negative regulation of cell aging)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NX47	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid:/w+L/oINlKM5ZSm1OkI+R+8PxXg9606	intact-crc:4D68855843421117|rigid:IyeDoifXUViJJCyegkZSxSP1/sY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q96EQ8	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341684|imex:IM-11696-252	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	intact-crc:BB875C0DD4D66773|rigid:cbvp0jJwXuyKgAMfmjK1N8i5aU4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q6PCD5	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-2129159|uniprotkb:Q9H9Q3|uniprotkb:Q9NVT4|uniprotkb:Q5XKR3|uniprotkb:A8K585|uniprotkb:B2RE35|uniprotkb:D3DUJ8|ensembl:ENSP00000354361|ensembl:ENSP00000460049	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:rfwd3_human(display_long)|uniprotkb:RFWD3(gene name)|psi-mi:RFWD3(display_short)|uniprotkb:RING finger and WD repeat domain-containing protein 3(gene name synonym)|uniprotkb:RNF201(gene name synonym)|uniprotkb:RING finger protein 201(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341687|imex:IM-11696-253	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	refseq:XP_011521493.1|refseq:NP_060594.3|refseq:XP_016878880.1|refseq:XP_005256078.1|refseq:XP_005256079.1|dip:DIP-52688N|ensembl:ENSG00000168411(gene)|ensembl:ENST00000361070(transcript)|ensembl:ENST00000571750(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031297"(replication fork processing)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037381|rcsb pdb:6CVZ	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid:r7gkMbkS0GKPVn9riLPR34KFaKk9606	intact-crc:787224AAF0C745E5|rigid:p4vpnVOqXavZLHo9aM3UoEcFSxE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q9C035	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-924214|uniprotkb:Q2MLV4|uniprotkb:Q2MLV8|uniprotkb:Q2MLV9|uniprotkb:Q2MLW1|uniprotkb:Q2MLW3|uniprotkb:Q2MLW4|uniprotkb:A6NGQ1|uniprotkb:Q2MLW6|uniprotkb:Q2MLW7|uniprotkb:Q2MLX1|uniprotkb:Q2MLX2|uniprotkb:Q2MLX3|uniprotkb:Q2MLX5|uniprotkb:Q2MLY3|uniprotkb:Q2MLY4|uniprotkb:Q2V6Q6|uniprotkb:Q6GX26|uniprotkb:Q8WU46|uniprotkb:Q96SR5|uniprotkb:Q9C031|uniprotkb:Q9C032|uniprotkb:Q9C033|uniprotkb:Q9C034|uniprotkb:A8WFA8|uniprotkb:D3DQS8|uniprotkb:D3DQS9|uniprotkb:G3GJY1|ensembl:ENSP00000369373|ensembl:ENSP00000507420	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:trim5_human(display_long)|uniprotkb:TRIM5(gene name)|psi-mi:TRIM5(display_short)|uniprotkb:RNF88(gene name synonym)|uniprotkb:RING finger protein 88(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341696|imex:IM-11696-256	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	refseq:NP_149023.2|refseq:NP_149083.2|refseq:NP_149084.2|refseq:XP_011518729.1|refseq:XP_005253240.1|refseq:XP_005253241.1|ensembl:ENSG00000132256(gene)|ensembl:ENST00000380034(transcript)|ensembl:ENST00000684655(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031664"(regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR043136|rcsb pdb:2ECV|rcsb pdb:2YRG|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid:t0YqhaJC8oQcwot7oks1LgMxdNc9606	intact-crc:E6430DC560DBF6A0|rigid:+QlnrLUtwR37xahV0rF4eEX1Kbc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q96EP1	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-718923|uniprotkb:A6NEN5|uniprotkb:Q96SL3|uniprotkb:Q9NRT4|uniprotkb:Q9NT32|uniprotkb:Q9NVD5|uniprotkb:B4DZ77|uniprotkb:B4E2L6|ensembl:ENSP00000392395	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:chfr_human(display_long)|uniprotkb:Checkpoint with forkhead and RING finger domains protein(gene name synonym)|uniprotkb:RING finger protein 196(gene name synonym)|uniprotkb:CHFR(gene name)|psi-mi:CHFR(display_short)|uniprotkb:RNF196(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHFR(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341690|imex:IM-11696-254	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	refseq:NP_001154816.1|refseq:NP_001154817.1|refseq:NP_001154818.1|refseq:NP_001154819.1|refseq:NP_060693.2|ensembl:ENSG00000072609(gene)|ensembl:ENST00000432561(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR019406|interpro:IPR040909|rcsb pdb:1LGP|rcsb pdb:1LGQ|rcsb pdb:2XOC|rcsb pdb:2XOY|rcsb pdb:2XOZ|rcsb pdb:2XP0|dip:DIP-40098N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid://FU72n6rmuPAu+Fjm377S4nEjw9606	intact-crc:D0B2BA06E2C0D3A0|rigid:wSuzLOV2BUypTBNuU5S6QdRF9EY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q9H992	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-949983|ensembl:ENSP00000386830|ensembl:ENSP00000259050|uniprotkb:Q53GQ1|uniprotkb:Q9BTR9|uniprotkb:A8K9X1|uniprotkb:D3DPB0|uniprotkb:B7Z7P5	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:marh7_human(display_long)|uniprotkb:MARCHF7(gene name)|psi-mi:MARCHF7(display_short)|uniprotkb:AXOT(gene name synonym)|uniprotkb:Axotrophin(gene name synonym)|uniprotkb:MARCH7(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 7(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein VII(gene name synonym)|uniprotkb:RING finger protein 177(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF7(gene name synonym)|uniprotkb:RNF177(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341693|imex:IM-11696-255	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	refseq:NP_001269734.1|refseq:NP_001269735.1|refseq:NP_001269736.1|ensembl:ENST00000259050(transcript)|ensembl:ENST00000409175(transcript)|go:"GO:0002643"(regulation of tolerance induction)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016740"(transferase activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050821"(protein stabilization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|ensembl:ENSG00000136536(gene)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_073737.1|refseq:XP_005246830.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid:HT4KtjhOVdeP4mam5eQhgX+ib5A9606	intact-crc:DB13AADA107FCF96|rigid:ihkmB96rFT8gROG/jWcqJqMUM/E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q6UWE0	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-720984|uniprotkb:Q5VVV0|uniprotkb:Q8NB40|uniprotkb:Q96GT5|uniprotkb:Q96MX5|uniprotkb:Q96MZ7|ensembl:ENSP00000300417|ensembl:ENSP00000322937|ensembl:ENSP00000362419|ensembl:ENSP00000502167	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:lrsm1_human(display_long)|uniprotkb:Leucine-rich repeat and sterile alpha motif-containing protein 1(gene name synonym)|uniprotkb:Tsg101-associated ligase(gene name synonym)|uniprotkb:LRSAM1(gene name)|psi-mi:LRSAM1(display_short)|uniprotkb:TAL(gene name synonym)|uniprotkb:UNQ6496/PRO21356(orf name)|uniprotkb:RING-type E3 ubiquitin transferase LRSAM1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341699|imex:IM-11696-257	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	refseq:NP_001005373.1|refseq:NP_001005374.1|refseq:NP_001177652.1|refseq:NP_612370.3|refseq:XP_016870772.1|ensembl:ENSG00000148356(gene)|ensembl:ENST00000300417(transcript)|ensembl:ENST00000323301(transcript)|ensembl:ENST00000373322(transcript)|ensembl:ENST00000675448(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0046755"(viral budding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032675|mint:Q6UWE0|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid:qkwPqOsfNjZBB2Xp6YAA9FbEZxM9606	intact-crc:EC53C54945E6A08A|rigid:gLK/iCdEwK44wAHbfSsqoSnRPRE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61088	uniprotkb:Q96P09	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-2341055|uniprotkb:Q96RW5|uniprotkb:Q6IPY1	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:birc8_human(display_long)|uniprotkb:BIRC8(gene name)|psi-mi:BIRC8(display_short)|uniprotkb:ILP2(gene name synonym)|uniprotkb:Inhibitor of apoptosis-like protein 2(gene name synonym)|uniprotkb:Testis-specific inhibitor of apoptosis(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341702|imex:IM-11696-258	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	interpro:IPR042579|refseq:NP_203127.3|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:1XB0|rcsb pdb:1XB1|interpro:IPR011029(DEATH-like)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid:dNa54zbu4SMSRJ8FXGBLuqGJ0qo9606	intact-crc:5EFCECB6DF0AB6D3|rigid:fndV4mX/yhbzzwrogfjl2dwwA3s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13404	uniprotkb:P98170	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341705|imex:IM-11696-259	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	intact-crc:2F18C3637B554A38|rigid:oTol57I0ToFHLItXusrq7bPRZP8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99496	uniprotkb:Q13404	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341708|imex:IM-11696-260	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	intact-crc:8F535C1AE5637039|rigid:yLZP8rGVKv8kKChGm4YfHA2Yn1E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13404	uniprotkb:Q86Y13	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341717|imex:IM-11696-263	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:56E8CCE1506BD56D|rigid:VUyWSkGiF5KiJyJSwLTYzwZcDv0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13404	uniprotkb:Q99942	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341711|imex:IM-11696-261	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606	intact-crc:38990515DEF8273D|rigid:yue3z9gX3PAz8EcK1+KNVe5gSts	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13404	uniprotkb:Q13064	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-2340269|ensembl:ENSP00000313881	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341714|imex:IM-11696-262	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606	intact-crc:D9B793C759DC0464|rigid:+g2XV9Hqb67QcYPWqLh/0LcGoTY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13404	uniprotkb:O95376	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-711158|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9|ensembl:ENSP00000348769|ensembl:ENSP00000403222	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341726|imex:IM-11696-266	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|ensembl:ENSG00000177479(gene)|ensembl:ENST00000356401(transcript)|ensembl:ENST00000449376(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|refseq:XP_016861020.1|refseq:XP_016861021.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	intact-crc:96D078D02DC2E17A|rigid:opXu4lWTgUFwLDL+Kle3rSMF6gE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13404	uniprotkb:P50876	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-2340657|uniprotkb:Q585H5|uniprotkb:D6W4Y6|ensembl:ENSP00000321330	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:r144a_human(display_long)|uniprotkb:RNF144A(gene name)|psi-mi:RNF144A(display_short)|uniprotkb:KIAA0161(gene name synonym)|uniprotkb:RNF144(gene name synonym)|uniprotkb:UBCE7IP4(gene name synonym)|uniprotkb:RING finger protein 144A(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 4(gene name synonym)|uniprotkb:UbcM4-interacting protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341720|imex:IM-11696-264	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	refseq:NP_055561.2|refseq:XP_016860885.1|refseq:XP_005246257.1|refseq:XP_005246259.1|refseq:XP_016860886.1|ensembl:ENSG00000151692(gene)|ensembl:ENST00000320892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031127|interpro:IPR044066|mint:P50876|rcsb pdb:1WIM|rcsb pdb:6L99|reactome:R-HSA-8866654	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:i2Ls6RkN4dTdPkBoso7ZDyIqi+g9606	intact-crc:C5F016C0F3946A6E|rigid:5KO7guldxmvJLfONJjC6CcvhDjw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13404	uniprotkb:Q8N5U6	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-714023|uniprotkb:Q92550|uniprotkb:Q9NPP8|uniprotkb:Q9ULW4|ensembl:ENSP00000322242	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:rnf10_human(display_long)|uniprotkb:RNF10(gene name)|psi-mi:RNF10(display_short)|uniprotkb:KIAA0262(gene name synonym)|uniprotkb:RIE2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341723|imex:IM-11696-265	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	refseq:NP_055683.3|refseq:NP_001317403.1|ensembl:ENSG00000022840(gene)|ensembl:ENST00000325954(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039739|mint:Q8N5U6	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:Bca0Ae456x1eCsdlduoCbn7coUQ9606	intact-crc:F74AAA6F3920F39A|rigid:nte2rim9ZdvaaceZVGir+g+YmGM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13049	uniprotkb:Q13404	intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym)	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341729|imex:IM-11696-267	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	intact-crc:B9B7962559DC07F4|rigid:hTVWkToU/bZ4UKD8YTbtp3zkzes	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6ZNA4	uniprotkb:Q13404	intact:EBI-2129175|uniprotkb:Q6ZMU2|uniprotkb:Q7L428|uniprotkb:Q7Z346|uniprotkb:Q8N1P9|uniprotkb:Q8WUA3|uniprotkb:Q9NSR1|uniprotkb:Q6P9A4|uniprotkb:C9JUS4|uniprotkb:H0YN55|ensembl:ENSP00000452732|intact:EBI-28970158	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	psi-mi:rn111_human(display_long)|uniprotkb:RNF111(gene name)|psi-mi:RNF111(display_short)|uniprotkb:RING finger protein 111(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Arkadia(gene name synonym)	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341732|imex:IM-11696-268	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060080.6|ensembl:ENST00000348370|ensembl:ENSP00000288199|ensembl:ENSP00000452732|ensembl:ENST00000559209|ensembl:ENSP00000453872|ensembl:ENST00000561186|ensembl:ENSP00000453015|refseq:NP_001317260.1|refseq:XP_016877827.1|refseq:XP_006720642.1|refseq:NP_001257459.1|refseq:NP_001257457.1|refseq:NP_001257458.1|ensembl:ENSG00000157450(gene)|ensembl:ENST00000557998(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR029306|rcsb pdb:2KIZ|rcsb pdb:5LG0|rcsb pdb:5LG7|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-5696395|reactome:R-HSA-983168|go:"GO:0032184"(SUMO polymer binding)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:6SY5oMr5u4mnVi+zdRboVljMGa09606	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	intact-crc:2D9226AAE2CEFAC5|rigid:af0BrZLZpTwIeyMvLMXsQU/4h3g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13404	uniprotkb:Q96GF1	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-2340249|uniprotkb:A8K5C1|uniprotkb:A9X3T8|uniprotkb:Q8N900|ensembl:ENSP00000320508|ensembl:ENSP00000427755	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:rn185_human(display_long)|uniprotkb:RNF185(gene name)|psi-mi:RNF185(display_short)|uniprotkb:RING finger protein 185(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF185(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341741|imex:IM-11696-271	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	refseq:NP_001129297.1|refseq:NP_689480.2|ensembl:ENSG00000138942(gene)|ensembl:ENST00000326132(transcript)|ensembl:ENST00000518626(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:ivzbt31KPTKL/Rc1Wzs3h80XJac9606	intact-crc:5E32A256AA44B526|rigid:fJn1cDA3e1ajExqbjGydRiBo46E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13404	uniprotkb:Q9HCM9	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-739510|uniprotkb:Q5STG4|uniprotkb:Q76BL3|uniprotkb:Q8IYT9|uniprotkb:Q96IB6|ensembl:ENSP00000365844|ensembl:ENSP00000373096|ensembl:ENSP00000379796|ensembl:ENSP00000391917|ensembl:ENSP00000397043|ensembl:ENSP00000398355|ensembl:ENSP00000409902|ensembl:ENSP00000411949|ensembl:ENSP00000447835|ensembl:ENSP00000448462|ensembl:ENSP00000448572|ensembl:ENSP00000449272|ensembl:ENSP00000449847|ensembl:ENSP00000450288|uniprotkb:Q5STG3	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:tri39_human(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341735|imex:IM-11696-269	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376656(transcript)|ensembl:ENST00000383602(transcript)|ensembl:ENST00000396547(transcript)|ensembl:ENST00000413715(transcript)|ensembl:ENST00000424575(transcript)|ensembl:ENST00000445206(transcript)|ensembl:ENST00000426469(transcript)|ensembl:ENST00000451715(transcript)|ensembl:ENST00000547030(transcript)|ensembl:ENST00000548002(transcript)|ensembl:ENST00000549841(transcript)|ensembl:ENST00000550282(transcript)|ensembl:ENST00000552337(transcript)|ensembl:ENST00000552520(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035033|interpro:IPR043136|mint:Q9HCM9|rcsb pdb:2DID|rcsb pdb:2DIF|rcsb pdb:2ECJ|reactome:R-HSA-983168|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_067076.2|refseq:NP_742013.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:xMCXGcMTqCjzLQzC53o81S4gqZA9606	intact-crc:65EC1D70A458575E|rigid:/d6nDxQ+fI9xulPZ+mK4+YTU4ig	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13404	uniprotkb:Q9C035	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-924214|uniprotkb:Q2MLV4|uniprotkb:Q2MLV8|uniprotkb:Q2MLV9|uniprotkb:Q2MLW1|uniprotkb:Q2MLW3|uniprotkb:Q2MLW4|uniprotkb:A6NGQ1|uniprotkb:Q2MLW6|uniprotkb:Q2MLW7|uniprotkb:Q2MLX1|uniprotkb:Q2MLX2|uniprotkb:Q2MLX3|uniprotkb:Q2MLX5|uniprotkb:Q2MLY3|uniprotkb:Q2MLY4|uniprotkb:Q2V6Q6|uniprotkb:Q6GX26|uniprotkb:Q8WU46|uniprotkb:Q96SR5|uniprotkb:Q9C031|uniprotkb:Q9C032|uniprotkb:Q9C033|uniprotkb:Q9C034|uniprotkb:A8WFA8|uniprotkb:D3DQS8|uniprotkb:D3DQS9|uniprotkb:G3GJY1|ensembl:ENSP00000369373|ensembl:ENSP00000507420	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:trim5_human(display_long)|uniprotkb:TRIM5(gene name)|psi-mi:TRIM5(display_short)|uniprotkb:RNF88(gene name synonym)|uniprotkb:RING finger protein 88(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341738|imex:IM-11696-270	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	refseq:NP_149023.2|refseq:NP_149083.2|refseq:NP_149084.2|refseq:XP_011518729.1|refseq:XP_005253240.1|refseq:XP_005253241.1|ensembl:ENSG00000132256(gene)|ensembl:ENST00000380034(transcript)|ensembl:ENST00000684655(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031664"(regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR043136|rcsb pdb:2ECV|rcsb pdb:2YRG|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:t0YqhaJC8oQcwot7oks1LgMxdNc9606	intact-crc:0D353CF7BE70D3A5|rigid:2bcsVjQqEc2vsF9a3yeVG+awgWA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P98170	uniprotkb:Q15819	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	intact:EBI-714329|ensembl:ENSP00000428209	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341750|imex:IM-11696-274	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606	intact-crc:732652EF9E5411D3|rigid:3kjp6ZKsWRJgLf2ic7LmXlHz9g8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96P09	uniprotkb:Q13404	intact:EBI-2341055|uniprotkb:Q96RW5|uniprotkb:Q6IPY1	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	psi-mi:birc8_human(display_long)|uniprotkb:BIRC8(gene name)|psi-mi:BIRC8(display_short)|uniprotkb:ILP2(gene name synonym)|uniprotkb:Inhibitor of apoptosis-like protein 2(gene name synonym)|uniprotkb:Testis-specific inhibitor of apoptosis(gene name synonym)	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341744|imex:IM-11696-272	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR042579|refseq:NP_203127.3|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:1XB0|rcsb pdb:1XB1|interpro:IPR011029(DEATH-like)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dNa54zbu4SMSRJ8FXGBLuqGJ0qo9606	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	intact-crc:B58ADD8401A193D6|rigid:2+1kkRbqgUIgI29/gcWAZvqJPdI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13404	uniprotkb:Q8N9I9	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-2340258|uniprotkb:Q8NDS8|uniprotkb:Q8NAU6|uniprotkb:Q53ZZ2|ensembl:ENSP00000338050|ensembl:ENSP00000447873|ensembl:ENSP00000449294	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:dtx3_human(display_long)|uniprotkb:DTX3(gene name)|psi-mi:DTX3(display_short)|uniprotkb:RNF154(gene name synonym)|uniprotkb:RING finger protein 154(gene name synonym)|uniprotkb:Protein deltex-3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341747|imex:IM-11696-273	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	refseq:NP_001273174.1|refseq:NP_001273175.1|refseq:XP_011536324.1|refseq:NP_848597.1|refseq:XP_005268754.1|refseq:XP_005268755.1|refseq:XP_005268757.1|refseq:XP_005268760.1|ensembl:ENSG00000178498(gene)|ensembl:ENST00000337737(transcript)|ensembl:ENST00000548198(transcript)|ensembl:ENST00000548804(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:Ma7JBhgMdFofCeWESbf8h1iLAHY9606	intact-crc:BA8EE881BFB7CE49|rigid:tIr5gQ35ZrMocxC/f/ddTfprG/A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99496	uniprotkb:Q15819	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480	intact:EBI-714329|ensembl:ENSP00000428209	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341753|imex:IM-11696-275	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750	rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606	intact-crc:84126BB08DF3A8C4|rigid:ode7+LJuz9PRIhcGh+2J1MMo3kk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15819	uniprotkb:Q8IUQ4	intact:EBI-714329|ensembl:ENSP00000428209	intact:EBI-747107|uniprotkb:O43269|uniprotkb:Q49A58|uniprotkb:A0FKF3|uniprotkb:Q92880|ensembl:ENSP00000369343|ensembl:ENSP00000378214|ensembl:ENSP00000456421	psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym)	psi-mi:siah1_human(display_long)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341756|imex:IM-11696-276	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N	refseq:XP_006721309.1|refseq:NP_001006611.1|refseq:NP_003022.3|refseq:XP_011521581.1|ensembl:ENST00000380006(transcript)|ensembl:ENST00000394725(transcript)|ensembl:ENST00000568007(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|mint:Q8IUQ4|rcsb pdb:2A25|rcsb pdb:4C9Z|rcsb pdb:4CA1|rcsb pdb:4I7B|rcsb pdb:4I7C|rcsb pdb:4I7D|rcsb pdb:4X3G|rcsb pdb:5WZZ|reactome:R-HSA-373752|reactome:R-HSA-977225|reactome:R-HSA-983168|ensembl:ENSG00000196470(gene)|dip:DIP-35684N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606	rogid:O6+z1g9K1ij87Xgo5/Ykl5Q3vUQ9606	intact-crc:1713CE616B126665|rigid:mselHN9HJhg9g3NanPDfMSoKY1c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P50876	uniprotkb:Q15819	intact:EBI-2340657|uniprotkb:Q585H5|uniprotkb:D6W4Y6|ensembl:ENSP00000321330	intact:EBI-714329|ensembl:ENSP00000428209	psi-mi:r144a_human(display_long)|uniprotkb:RNF144A(gene name)|psi-mi:RNF144A(display_short)|uniprotkb:KIAA0161(gene name synonym)|uniprotkb:RNF144(gene name synonym)|uniprotkb:UBCE7IP4(gene name synonym)|uniprotkb:RING finger protein 144A(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 4(gene name synonym)|uniprotkb:UbcM4-interacting protein 4(gene name synonym)	psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341765|imex:IM-11696-279	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055561.2|refseq:XP_016860885.1|refseq:XP_005246257.1|refseq:XP_005246259.1|refseq:XP_016860886.1|ensembl:ENSG00000151692(gene)|ensembl:ENST00000320892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031127|interpro:IPR044066|mint:P50876|rcsb pdb:1WIM|rcsb pdb:6L99|reactome:R-HSA-8866654	rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:i2Ls6RkN4dTdPkBoso7ZDyIqi+g9606	rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606	intact-crc:99CE874C16953185|rigid:Tv1yXDp6MxuR9HAwmu6MIFl9kuI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15819	uniprotkb:Q13064	intact:EBI-714329|ensembl:ENSP00000428209	intact:EBI-2340269|ensembl:ENSP00000313881	psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym)	psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341759|imex:IM-11696-277	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N	refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606	rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606	intact-crc:8589024BBCDD5F8F|rigid:E8aUt05Snf0xixZB8D6G+glA8Lw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15819	uniprotkb:Q86Y13	intact:EBI-714329|ensembl:ENSP00000428209	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341762|imex:IM-11696-278	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:5DA9FB4B38FB0D90|rigid:Pc2U/wgN74Ve0kJHvUU10jsNNKI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6ZNA4	uniprotkb:P61081	intact:EBI-2129175|uniprotkb:Q6ZMU2|uniprotkb:Q7L428|uniprotkb:Q7Z346|uniprotkb:Q8N1P9|uniprotkb:Q8WUA3|uniprotkb:Q9NSR1|uniprotkb:Q6P9A4|uniprotkb:C9JUS4|uniprotkb:H0YN55|ensembl:ENSP00000452732|intact:EBI-28970158	intact:EBI-1041660|uniprotkb:O76069|uniprotkb:Q8VC50|ensembl:ENSP00000253023	psi-mi:rn111_human(display_long)|uniprotkb:RNF111(gene name)|psi-mi:RNF111(display_short)|uniprotkb:RING finger protein 111(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Arkadia(gene name synonym)	psi-mi:ubc12_human(display_long)|uniprotkb:UBE2M(gene name)|psi-mi:UBE2M(display_short)|uniprotkb:UBC12(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 M(gene name synonym)|uniprotkb:NEDD8 carrier protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341774|imex:IM-11696-282	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060080.6|ensembl:ENST00000348370|ensembl:ENSP00000288199|ensembl:ENSP00000452732|ensembl:ENST00000559209|ensembl:ENSP00000453872|ensembl:ENST00000561186|ensembl:ENSP00000453015|refseq:NP_001317260.1|refseq:XP_016877827.1|refseq:XP_006720642.1|refseq:NP_001257459.1|refseq:NP_001257457.1|refseq:NP_001257458.1|ensembl:ENSG00000157450(gene)|ensembl:ENST00000557998(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR029306|rcsb pdb:2KIZ|rcsb pdb:5LG0|rcsb pdb:5LG7|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-5696395|reactome:R-HSA-983168|go:"GO:0032184"(SUMO polymer binding)	refseq:NP_003960.1|ensembl:ENSG00000130725(gene)|ensembl:ENST00000253023(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045116"(protein neddylation)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61081|reactome:R-HSA-8951664|reactome:R-HSA-983168|rcsb pdb:1TT5|rcsb pdb:1Y8X|rcsb pdb:2NVU|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4GAO|rcsb pdb:4P5O|reactome:R-HSA-2173789|reactome:R-HSA-5607761|reactome:R-HSA-5676590|dip:DIP-35679N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:6SY5oMr5u4mnVi+zdRboVljMGa09606	rogid:YfRvkrP+nGQTtjeUsJNDbMm1Nqo9606	intact-crc:391BEE983C65DD10|rigid:60WWaeZdxFIo84ELaVGmLir1b4g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15819	uniprotkb:Q8ND25	intact:EBI-714329|ensembl:ENSP00000428209	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym)	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341768|imex:IM-11696-280	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	intact-crc:3A179DAFFD3D23AC|rigid:KPynPxLnA/FblR8xccGu/9jBxf0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15819	uniprotkb:Q9C035	intact:EBI-714329|ensembl:ENSP00000428209	intact:EBI-924214|uniprotkb:Q2MLV4|uniprotkb:Q2MLV8|uniprotkb:Q2MLV9|uniprotkb:Q2MLW1|uniprotkb:Q2MLW3|uniprotkb:Q2MLW4|uniprotkb:A6NGQ1|uniprotkb:Q2MLW6|uniprotkb:Q2MLW7|uniprotkb:Q2MLX1|uniprotkb:Q2MLX2|uniprotkb:Q2MLX3|uniprotkb:Q2MLX5|uniprotkb:Q2MLY3|uniprotkb:Q2MLY4|uniprotkb:Q2V6Q6|uniprotkb:Q6GX26|uniprotkb:Q8WU46|uniprotkb:Q96SR5|uniprotkb:Q9C031|uniprotkb:Q9C032|uniprotkb:Q9C033|uniprotkb:Q9C034|uniprotkb:A8WFA8|uniprotkb:D3DQS8|uniprotkb:D3DQS9|uniprotkb:G3GJY1|ensembl:ENSP00000369373|ensembl:ENSP00000507420	psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym)	psi-mi:trim5_human(display_long)|uniprotkb:TRIM5(gene name)|psi-mi:TRIM5(display_short)|uniprotkb:RNF88(gene name synonym)|uniprotkb:RING finger protein 88(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341771|imex:IM-11696-281	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N	refseq:NP_149023.2|refseq:NP_149083.2|refseq:NP_149084.2|refseq:XP_011518729.1|refseq:XP_005253240.1|refseq:XP_005253241.1|ensembl:ENSG00000132256(gene)|ensembl:ENST00000380034(transcript)|ensembl:ENST00000684655(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031664"(regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR043136|rcsb pdb:2ECV|rcsb pdb:2YRG|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606	rogid:t0YqhaJC8oQcwot7oks1LgMxdNc9606	intact-crc:06740B5DD6E00B58|rigid:uksYUk7VHN8Z2A1IkUep9BaHYaw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14933	uniprotkb:P14373	intact:EBI-2129974|uniprotkb:A6NDM6|uniprotkb:Q8N5D8|uniprotkb:A8MY53|uniprotkb:Q9UEZ0|ensembl:ENSP00000287156	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:ub2l6_human(display_long)|uniprotkb:UBE2L6(gene name)|psi-mi:UBE2L6(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L6(gene name synonym)|uniprotkb:Ubiquitin carrier protein L6(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:Retinoic acid-induced gene B protein(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L6(gene name synonym)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341777|imex:IM-11696-283	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004214.1|refseq:NP_937826.1|ensembl:ENSP00000287156|ensembl:ENST00000340573|ensembl:ENSP00000341980|dip:DIP-41477N|ensembl:ENSG00000156587(gene)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:O14933|rcsb pdb:1WZV|rcsb pdb:1WZW|rcsb pdb:2KJH|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|ensembl:ENST00000287156(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|reactome:R-HSA-936440|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032020"(ISG15-protein conjugation)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:18K+ReSJfSpKRvnLuED+kPB3beY9606	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:D0A1819BCDCEE189|rigid:dl1jlO+D64j3Vibs2eLxSGEwoJw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14933	uniprotkb:Q9ULV8	intact:EBI-2129974|uniprotkb:A6NDM6|uniprotkb:Q8N5D8|uniprotkb:A8MY53|uniprotkb:Q9UEZ0|ensembl:ENSP00000287156	intact:EBI-2341018|uniprotkb:Q9Y5Z3|uniprotkb:Q8N1E5|uniprotkb:Q9Y5Z2|intact:EBI-28975910|ensembl:ENSP00000494162	psi-mi:ub2l6_human(display_long)|uniprotkb:UBE2L6(gene name)|psi-mi:UBE2L6(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L6(gene name synonym)|uniprotkb:Ubiquitin carrier protein L6(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:Retinoic acid-induced gene B protein(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L6(gene name synonym)	psi-mi:cblc_human(display_long)|uniprotkb:CBLC(gene name)|psi-mi:CBLC(display_short)|uniprotkb:CBL3(gene name synonym)|uniprotkb:RNF57(gene name synonym)|uniprotkb:SH3-binding protein CBL-C(gene name synonym)|uniprotkb:SH3-binding protein CBL-3(gene name synonym)|uniprotkb:RING finger protein 57(gene name synonym)|uniprotkb:Signal transduction protein CBL-C(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CBL-C(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341780|imex:IM-11696-284	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004214.1|refseq:NP_937826.1|ensembl:ENSP00000287156|ensembl:ENST00000340573|ensembl:ENSP00000341980|dip:DIP-41477N|ensembl:ENSG00000156587(gene)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:O14933|rcsb pdb:1WZV|rcsb pdb:1WZW|rcsb pdb:2KJH|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|ensembl:ENST00000287156(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|reactome:R-HSA-936440|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032020"(ISG15-protein conjugation)	ensembl:ENST00000341505|ensembl:ENSP00000340250|ensembl:ENSP00000494162|refseq:NP_001124324.1|refseq:NP_036248.3|ensembl:ENSG00000142273(gene)|ensembl:ENST00000647358(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|rcsb pdb:3OP0|rcsb pdb:3VRN|rcsb pdb:3VRO|rcsb pdb:3VRP|rcsb pdb:3VRQ|rcsb pdb:3VRR	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:18K+ReSJfSpKRvnLuED+kPB3beY9606	rogid:syzTzR6RGJzLv2EpDirSrli4ghs9606	intact-crc:740F743CA25AE887|rigid:g1HLyiCei6+PprcqpBFJqjAbInA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZR9	uniprotkb:O14933	intact:EBI-2340370|uniprotkb:Q9C028|uniprotkb:A6NI31|intact:EBI-2796718|ensembl:ENSP00000496301	intact:EBI-2129974|uniprotkb:A6NDM6|uniprotkb:Q8N5D8|uniprotkb:A8MY53|uniprotkb:Q9UEZ0|ensembl:ENSP00000287156	psi-mi:trim8_human(display_long)|uniprotkb:Tripartite motif-containing protein 8(gene name synonym)|uniprotkb:TRIM8(gene name)|psi-mi:TRIM8(display_short)|uniprotkb:GERP(gene name synonym)|uniprotkb:RNF27(gene name synonym)|uniprotkb:RING finger protein 27(gene name synonym)|uniprotkb:Glioblastoma-expressed RING finger protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM8(gene name synonym)	psi-mi:ub2l6_human(display_long)|uniprotkb:UBE2L6(gene name)|psi-mi:UBE2L6(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L6(gene name synonym)|uniprotkb:Ubiquitin carrier protein L6(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:Retinoic acid-induced gene B protein(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341783|imex:IM-11696-285	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112174.2|ensembl:ENSG00000171206(gene)|ensembl:ENST00000643721(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0016740"(transferase activity)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902187"|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-877300	refseq:NP_004214.1|refseq:NP_937826.1|ensembl:ENSP00000287156|ensembl:ENST00000340573|ensembl:ENSP00000341980|dip:DIP-41477N|ensembl:ENSG00000156587(gene)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:O14933|rcsb pdb:1WZV|rcsb pdb:1WZW|rcsb pdb:2KJH|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|ensembl:ENST00000287156(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|reactome:R-HSA-936440|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032020"(ISG15-protein conjugation)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:WFqavXVFV3/XbJSA2k06Pg9Eaag9606	rogid:18K+ReSJfSpKRvnLuED+kPB3beY9606	intact-crc:689CA43A08EB32CA|rigid:aHuW7PW9CU3hL/68mByuzXWfZf0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14933	uniprotkb:Q17RB8	intact:EBI-2129974|uniprotkb:A6NDM6|uniprotkb:Q8N5D8|uniprotkb:A8MY53|uniprotkb:Q9UEZ0|ensembl:ENSP00000287156	intact:EBI-2341787|uniprotkb:Q9BSV1|uniprotkb:Q8TEA0|uniprotkb:B4DM29|uniprotkb:B4DU84|ensembl:ENSP00000381298	psi-mi:ub2l6_human(display_long)|uniprotkb:UBE2L6(gene name)|psi-mi:UBE2L6(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L6(gene name synonym)|uniprotkb:Ubiquitin carrier protein L6(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:Retinoic acid-induced gene B protein(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L6(gene name synonym)	psi-mi:lonf1_human(display_long)|uniprotkb:LONRF1(gene name)|psi-mi:LONRF1(display_short)|uniprotkb:RNF191(gene name synonym)|uniprotkb:RING finger protein 191(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341786|imex:IM-11696-481	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004214.1|refseq:NP_937826.1|ensembl:ENSP00000287156|ensembl:ENST00000340573|ensembl:ENSP00000341980|dip:DIP-41477N|ensembl:ENSG00000156587(gene)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:O14933|rcsb pdb:1WZV|rcsb pdb:1WZW|rcsb pdb:2KJH|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|ensembl:ENST00000287156(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|reactome:R-HSA-936440|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032020"(ISG15-protein conjugation)	refseq:NP_689484.3|refseq:NP_001316905.1|ensembl:ENSG00000154359(gene)|ensembl:ENST00000398246(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019734|interpro:IPR027370|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:18K+ReSJfSpKRvnLuED+kPB3beY9606	rogid:Mr6Gsz7VGfZgCTy8Yc7K2mhMSAU9606	intact-crc:35257A5D36EFCD6E|rigid:g7kXSPQqPxMN+PfCl7w+HeaZZfE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:O15344	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-2340316|uniprotkb:Q9BZX5|uniprotkb:O75361|uniprotkb:B2RCG2|ensembl:ENSP00000312678|ensembl:ENSP00000370156|ensembl:ENSP00000370157|ensembl:ENSP00000370162|ensembl:ENSP00000370164|ensembl:ENSP00000414521	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:tri18_human(display_long)|uniprotkb:MID1(gene name)|psi-mi:MID1(display_short)|uniprotkb:FXY(gene name synonym)|uniprotkb:RNF59(gene name synonym)|uniprotkb:TRIM18(gene name synonym)|uniprotkb:XPRF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 18(gene name synonym)|uniprotkb:Putative transcription factor XPRF(gene name synonym)|uniprotkb:Midin(gene name synonym)|uniprotkb:RING finger protein 59(gene name synonym)|uniprotkb:RING finger protein Midline-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Midline-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341795|imex:IM-11696-482	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_000372.1|refseq:NP_001092094.1|refseq:NP_001180206.1|refseq:NP_001180207.1|refseq:NP_001180208.1|refseq:NP_001180209.1|refseq:NP_001180210.1|refseq:NP_150632.1|refseq:NP_001334662.1|refseq:XP_016885025.1|refseq:XP_016885029.1|ensembl:ENSG00000101871(gene)|ensembl:ENST00000317552(transcript)|ensembl:ENST00000380779(transcript)|ensembl:ENST00000380780(transcript)|ensembl:ENST00000380785(transcript)|ensembl:ENST00000380787(transcript)|ensembl:ENST00000453318(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016740"(transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003649(B-box, C-terminal)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR027727|interpro:IPR036116|interpro:IPR040859|interpro:IPR043136|rcsb pdb:2DQ5|rcsb pdb:2FFW|rcsb pdb:2JUN|rcsb pdb:5IM8|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:NGlMGyFT7GEcrzVR/Iw4LitMBig9606	intact-crc:713903FAF6429AC8|rigid:3yACI3GDvTtmHwfE2Fz2MbBhGGE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06587	uniprotkb:Q969T4	intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym)	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341798|imex:IM-11696-483	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	intact-crc:400BD2C413CDEB33|rigid:YmLdNYZH16hDNC0mjud5yo7miLI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:P78317	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-2340927|uniprotkb:Q49AR8|uniprotkb:B2R6D6|uniprotkb:D6RF58|intact:EBI-28970119|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:rnf4_human(display_long)|uniprotkb:SNURF(gene name synonym)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:RNF4(gene name)|psi-mi:RNF4(display_short)|uniprotkb:RES4-26(orf name)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341801|imex:IM-11696-484	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_001171938.1|refseq:NP_001171939.1|refseq:NP_002929.1|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503|ensembl:ENST00000511859|ensembl:ENSP00000426615|ensembl:ENST00000541204|ensembl:ENSP00000446369|ensembl:ENSG00000063978(gene)|ensembl:ENST00000314289(transcript)|ensembl:ENST00000506706(transcript)|ensembl:ENST00000511600(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|go:"GO:1990752"(microtubule end)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|mint:P78317|rcsb pdb:2EA6|rcsb pdb:2XEU|rcsb pdb:4PPE|reactome:R-HSA-5693607|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:Yhu2iAaNQYcfGdYohDPBdhMFEpc9606	intact-crc:EEC4EFF60BF1A040|rigid:2vrwVkMfrE+yttYyqcgnFCxktHc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBS8	uniprotkb:Q969T4	intact:EBI-2130308|uniprotkb:B7ZLV2|uniprotkb:A0AV26|uniprotkb:A6NMR2|uniprotkb:B3KN72|uniprotkb:O94793|uniprotkb:Q6IBV0|uniprotkb:A8MTW5|uniprotkb:D3DQE4|ensembl:ENSP00000324956|ensembl:ENSP00000348462|ensembl:ENSP00000378027|ensembl:ENSP00000378028	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	psi-mi:rnf14_human(display_long)|uniprotkb:RNF14(gene name)|psi-mi:RNF14(display_short)|uniprotkb:ARA54(gene name synonym)|uniprotkb:RING finger protein 14(gene name synonym)|uniprotkb:Androgen receptor-associated protein 54(gene name synonym)|uniprotkb:Triad2 protein(gene name synonym)|uniprotkb:HFB30(gene name synonym)|uniprotkb:HRIHFB2038(orf name)	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341807|imex:IM-11696-486	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011536016.1|refseq:NP_001188294.1|refseq:NP_004281.1|refseq:NP_899645.1|refseq:NP_899646.1|refseq:NP_899647.1|refseq:NP_899648.1|refseq:XP_016865559.1|refseq:XP_016865560.1|refseq:XP_016865561.1|refseq:XP_005268593.1|refseq:XP_005268594.1|refseq:XP_005268596.1|refseq:XP_005268597.1|refseq:XP_005268598.1|ensembl:ENSG00000013561(gene)|ensembl:ENST00000347642(transcript)|ensembl:ENST00000356143(transcript)|ensembl:ENST00000394519(transcript)|ensembl:ENST00000394520(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017907|interpro:IPR031127|interpro:IPR031128|interpro:IPR044066|mint:Q9UBS8|reactome:R-HSA-983168	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:zCNZ6kHw7XNUvpVBRQSgZ7ffJ9U9606	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	intact-crc:64B778FB06C8307E|rigid:nqc7HeYGP9bZy0yweP6Hou93zWI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:O95376	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-711158|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9|ensembl:ENSP00000348769|ensembl:ENSP00000403222	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341810|imex:IM-11696-487	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|ensembl:ENSG00000177479(gene)|ensembl:ENST00000356401(transcript)|ensembl:ENST00000449376(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|refseq:XP_016861020.1|refseq:XP_016861021.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	intact-crc:20FE1DBCA317C905|rigid:Xj6l/4zmh0MA+8sA/0lEf0eISSE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:Q13064	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-2340269|ensembl:ENSP00000313881	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341804|imex:IM-11696-485	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606	intact-crc:6F99F6ABD7092C1B|rigid:OgLbG1JmpEuIYZ2xrOTXnKxRYDI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:Q9C040	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341813|imex:IM-11696-488	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	intact-crc:5678DA818857D2AB|rigid:pEu9Sah305BTuQm7E/ZwzpsgWaQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:Q6ZNA4	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-2129175|uniprotkb:Q6ZMU2|uniprotkb:Q7L428|uniprotkb:Q7Z346|uniprotkb:Q8N1P9|uniprotkb:Q8WUA3|uniprotkb:Q9NSR1|uniprotkb:Q6P9A4|uniprotkb:C9JUS4|uniprotkb:H0YN55|ensembl:ENSP00000452732|intact:EBI-28970158	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:rn111_human(display_long)|uniprotkb:RNF111(gene name)|psi-mi:RNF111(display_short)|uniprotkb:RING finger protein 111(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Arkadia(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341816|imex:IM-11696-489	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_060080.6|ensembl:ENST00000348370|ensembl:ENSP00000288199|ensembl:ENSP00000452732|ensembl:ENST00000559209|ensembl:ENSP00000453872|ensembl:ENST00000561186|ensembl:ENSP00000453015|refseq:NP_001317260.1|refseq:XP_016877827.1|refseq:XP_006720642.1|refseq:NP_001257459.1|refseq:NP_001257457.1|refseq:NP_001257458.1|ensembl:ENSG00000157450(gene)|ensembl:ENST00000557998(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR029306|rcsb pdb:2KIZ|rcsb pdb:5LG0|rcsb pdb:5LG7|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-5696395|reactome:R-HSA-983168|go:"GO:0032184"(SUMO polymer binding)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:6SY5oMr5u4mnVi+zdRboVljMGa09606	intact-crc:D435B6164488CDD0|rigid:3YOmLmtfIcEAV3eP8XKYGRp4HLE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:Q96A37	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-2130320|uniprotkb:B3KQ03|uniprotkb:Q96DM0|uniprotkb:D3DX75|uniprotkb:H3BTU8|ensembl:ENSP00000326095	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:rn166_human(display_long)|uniprotkb:RNF166(gene name)|psi-mi:RNF166(display_short)|uniprotkb:RING finger protein 166(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF166(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341825|imex:IM-11696-492	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_001165286.1|refseq:NP_001165287.1|refseq:NP_849163.1|refseq:XP_016878402.1|ensembl:ENSG00000158717(gene)|ensembl:ENST00000312838(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:QV195sbjVofHePvnO8nsleiWSkg9606	intact-crc:6A5279A611D5FB4F|rigid:yzYZ0bscKjHEur8vYnmHH/h4QAk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:Q6PCD5	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-2129159|uniprotkb:Q9H9Q3|uniprotkb:Q9NVT4|uniprotkb:Q5XKR3|uniprotkb:A8K585|uniprotkb:B2RE35|uniprotkb:D3DUJ8|ensembl:ENSP00000354361|ensembl:ENSP00000460049	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:rfwd3_human(display_long)|uniprotkb:RFWD3(gene name)|psi-mi:RFWD3(display_short)|uniprotkb:RING finger and WD repeat domain-containing protein 3(gene name synonym)|uniprotkb:RNF201(gene name synonym)|uniprotkb:RING finger protein 201(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341819|imex:IM-11696-490	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:XP_011521493.1|refseq:NP_060594.3|refseq:XP_016878880.1|refseq:XP_005256078.1|refseq:XP_005256079.1|dip:DIP-52688N|ensembl:ENSG00000168411(gene)|ensembl:ENST00000361070(transcript)|ensembl:ENST00000571750(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031297"(replication fork processing)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037381|rcsb pdb:6CVZ	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid:r7gkMbkS0GKPVn9riLPR34KFaKk9606	intact-crc:71391FF61439A037|rigid:W6OrWry9iNn1NVtRQoztAhJ3m4w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969T4	uniprotkb:Q96EP1	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	intact:EBI-718923|uniprotkb:A6NEN5|uniprotkb:Q96SL3|uniprotkb:Q9NRT4|uniprotkb:Q9NT32|uniprotkb:Q9NVD5|uniprotkb:B4DZ77|uniprotkb:B4E2L6|ensembl:ENSP00000392395	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:chfr_human(display_long)|uniprotkb:Checkpoint with forkhead and RING finger domains protein(gene name synonym)|uniprotkb:RING finger protein 196(gene name synonym)|uniprotkb:CHFR(gene name)|psi-mi:CHFR(display_short)|uniprotkb:RNF196(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHFR(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341822|imex:IM-11696-491	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	refseq:NP_001154816.1|refseq:NP_001154817.1|refseq:NP_001154818.1|refseq:NP_001154819.1|refseq:NP_060693.2|ensembl:ENSG00000072609(gene)|ensembl:ENST00000432561(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR019406|interpro:IPR040909|rcsb pdb:1LGP|rcsb pdb:1LGQ|rcsb pdb:2XOC|rcsb pdb:2XOY|rcsb pdb:2XOZ|rcsb pdb:2XP0|dip:DIP-40098N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rogid://FU72n6rmuPAu+Fjm377S4nEjw9606	intact-crc:A2BB1B30398BA5DD|rigid:VCLb5ZRf8zoVfPxeKVo3l9U7OcQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NPD8	uniprotkb:O60291	intact:EBI-2130165|uniprotkb:Q2TU36|ensembl:ENSP00000494957	intact:EBI-2129851|uniprotkb:A4URL3|uniprotkb:A4URL4|uniprotkb:Q86W76|intact:EBI-28986785|ensembl:ENSP00000382487	psi-mi:ube2t_human(display_long)|uniprotkb:UBE2T(gene name)|psi-mi:UBE2T(display_short)|uniprotkb:Ubiquitin-protein ligase T(gene name synonym)|uniprotkb:Ubiquitin carrier protein T(gene name synonym)|uniprotkb:HSPC150(orf name)|uniprotkb:Cell proliferation-inducing gene 50 protein(gene name synonym)|uniprotkb:PIG50(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme T(gene name synonym)	psi-mi:mgrn1_human(display_long)|uniprotkb:MGRN1(gene name)|psi-mi:MGRN1(display_short)|uniprotkb:KIAA0544(gene name synonym)|uniprotkb:RNF156(gene name synonym)|uniprotkb:Mahogunin RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 156(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MGRN1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341834|imex:IM-11696-288	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054895.1|refseq:NP_001297255.1|dip:DIP-52740N|ensembl:ENSG00000077152(gene)|ensembl:ENST00000646651(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YH2|rcsb pdb:4CCG|rcsb pdb:5NGZ|rcsb pdb:5OJJ|rcsb pdb:6R75|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|reactome:R-HSA-8866652	refseq:NP_001135761.2|refseq:NP_001135762.1|refseq:NP_001135763.2|refseq:NP_056061.1|ensembl:ENST00000262370|ensembl:ENSP00000262370|ensembl:ENSP00000382487|ensembl:ENST00000415496|ensembl:ENSP00000393311|ensembl:ENST00000586183|ensembl:ENSP00000465860|ensembl:ENST00000588994|ensembl:ENSP00000468819|refseq:XP_005255277.1|refseq:XP_005255278.1|ensembl:ENSG00000102858(gene)|ensembl:ENST00000399577(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hKFqKCWzIhcGshB1ut+mTTSwxbQ9606	rogid:UuLoCnlkpTBs/rmGgpQvgiMNuNE9606	intact-crc:65B087731BDA5BC4|rigid:/STssbt9/QSLH5pvaY67tcnOxHw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N9I9	uniprotkb:Q969T4	intact:EBI-2340258|uniprotkb:Q8NDS8|uniprotkb:Q8NAU6|uniprotkb:Q53ZZ2|ensembl:ENSP00000338050|ensembl:ENSP00000447873|ensembl:ENSP00000449294	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	psi-mi:dtx3_human(display_long)|uniprotkb:DTX3(gene name)|psi-mi:DTX3(display_short)|uniprotkb:RNF154(gene name synonym)|uniprotkb:RING finger protein 154(gene name synonym)|uniprotkb:Protein deltex-3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3(gene name synonym)	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341828|imex:IM-11696-286	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273174.1|refseq:NP_001273175.1|refseq:XP_011536324.1|refseq:NP_848597.1|refseq:XP_005268754.1|refseq:XP_005268755.1|refseq:XP_005268757.1|refseq:XP_005268760.1|ensembl:ENSG00000178498(gene)|ensembl:ENST00000337737(transcript)|ensembl:ENST00000548198(transcript)|ensembl:ENST00000548804(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Ma7JBhgMdFofCeWESbf8h1iLAHY9606	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	intact-crc:C91BFF41849BD699|rigid:3qC2OSdxTzKy1vrE1qEkc/UHcLQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BYM8	uniprotkb:Q16763	intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632	intact:EBI-2339823|uniprotkb:Q9BTC1|ensembl:ENSP00000264552	psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym)	psi-mi:ube2s_human(display_long)|uniprotkb:UBE2S(gene name)|psi-mi:UBE2S(display_short)|uniprotkb:E2EPF(gene name synonym)|uniprotkb:Ubiquitin-protein ligase S(gene name synonym)|uniprotkb:Ubiquitin carrier protein S(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-24 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-EPF5(gene name synonym)|uniprotkb:OK/SW-cl.73(orf name)|uniprotkb:E2-EPF(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme S(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341831|imex:IM-11696-287	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006453.1|refseq:NP_112506.2|ensembl:ENSG00000125826(gene)|ensembl:ENST00000356286(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR026261|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|dip:DIP-47737N	refseq:NP_055316.2|dip:DIP-52784N|ensembl:ENSG00000108106(gene)|ensembl:ENST00000264552(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051301"(cell division)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1ZDN|rcsb pdb:5BNB|rcsb pdb:5L9T|rcsb pdb:6QH3|rcsb pdb:6QHK|rcsb pdb:6S96|rcsb pdb:6S98|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-9687136|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606	rogid:PiLqBXIHRM8f6hlUXU6PkI3xNtM9606	intact-crc:F926E1518510B0F8|rigid:uYa7MW/KENISMao3grZJiSETlGc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NPD8	uniprotkb:Q8N448	intact:EBI-2130165|uniprotkb:Q2TU36|ensembl:ENSP00000494957	intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224	psi-mi:ube2t_human(display_long)|uniprotkb:UBE2T(gene name)|psi-mi:UBE2T(display_short)|uniprotkb:Ubiquitin-protein ligase T(gene name synonym)|uniprotkb:Ubiquitin carrier protein T(gene name synonym)|uniprotkb:HSPC150(orf name)|uniprotkb:Cell proliferation-inducing gene 50 protein(gene name synonym)|uniprotkb:PIG50(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme T(gene name synonym)	psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341843|imex:IM-11696-291	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054895.1|refseq:NP_001297255.1|dip:DIP-52740N|ensembl:ENSG00000077152(gene)|ensembl:ENST00000646651(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YH2|rcsb pdb:4CCG|rcsb pdb:5NGZ|rcsb pdb:5OJJ|rcsb pdb:6R75|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|reactome:R-HSA-8866652	refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hKFqKCWzIhcGshB1ut+mTTSwxbQ9606	rogid:cIS5t4XkbnIgelDlUc692nI285g9606	intact-crc:58EB314F70559AA9|rigid:FkrYilJ3lOKVqKrapK1ardb13wQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NPD8	uniprotkb:Q8TEB7	intact:EBI-2130165|uniprotkb:Q2TU36|ensembl:ENSP00000494957	intact:EBI-2341619|uniprotkb:Q6ZTJ8|uniprotkb:Q9H5E4|uniprotkb:Q96RF3|uniprotkb:Q6PH80|uniprotkb:A0PJI4|ensembl:ENSP00000255499	psi-mi:ube2t_human(display_long)|uniprotkb:UBE2T(gene name)|psi-mi:UBE2T(display_short)|uniprotkb:Ubiquitin-protein ligase T(gene name synonym)|uniprotkb:Ubiquitin carrier protein T(gene name synonym)|uniprotkb:HSPC150(orf name)|uniprotkb:Cell proliferation-inducing gene 50 protein(gene name synonym)|uniprotkb:PIG50(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme T(gene name synonym)	psi-mi:rn128_human(display_long)|uniprotkb:RNF128(gene name)|psi-mi:RNF128(display_short)|uniprotkb:RING finger protein 128(gene name synonym)|uniprotkb:Gene related to anergy in lymphocytes protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF128(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341840|imex:IM-11696-290	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054895.1|refseq:NP_001297255.1|dip:DIP-52740N|ensembl:ENSG00000077152(gene)|ensembl:ENST00000646651(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YH2|rcsb pdb:4CCG|rcsb pdb:5NGZ|rcsb pdb:5OJJ|rcsb pdb:6R75|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|reactome:R-HSA-8866652	refseq:NP_078815.3|refseq:NP_919445.1|ensembl:ENSG00000133135(gene)|ensembl:ENST00000255499(transcript)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1904352"(positive regulation of protein catabolic process in the vacuole)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:3ICU|reactome:R-HSA-5689880|reactome:R-HSA-5689896	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hKFqKCWzIhcGshB1ut+mTTSwxbQ9606	rogid:rHG5hoB/R1yW2BDsMr7LJEAXAWw9606	intact-crc:2067F18F96422F52|rigid:T3p8OMRxUZtt0CTyrvoOGITn7Ok	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NX47	uniprotkb:Q9NPD8	intact:EBI-2341610|ensembl:ENSP00000351813	intact:EBI-2130165|uniprotkb:Q2TU36|ensembl:ENSP00000494957	psi-mi:marh5_human(display_long)|uniprotkb:MARCH5(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 5(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein V(gene name synonym)|uniprotkb:Mitochondrial ubiquitin ligase(gene name synonym)|uniprotkb:RING finger protein 153(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF5(gene name synonym)|uniprotkb:MARCHF5(gene name)|psi-mi:MARCHF5(display_short)|uniprotkb:RNF153(gene name synonym)	psi-mi:ube2t_human(display_long)|uniprotkb:UBE2T(gene name)|psi-mi:UBE2T(display_short)|uniprotkb:Ubiquitin-protein ligase T(gene name synonym)|uniprotkb:Ubiquitin carrier protein T(gene name synonym)|uniprotkb:HSPC150(orf name)|uniprotkb:Cell proliferation-inducing gene 50 protein(gene name synonym)|uniprotkb:PIG50(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme T(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341837|imex:IM-11696-289	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060294.1|ensembl:ENSG00000198060(gene)|ensembl:ENST00000358935(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051020"(GTPase binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090344"(negative regulation of cell aging)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NX47	refseq:NP_054895.1|refseq:NP_001297255.1|dip:DIP-52740N|ensembl:ENSG00000077152(gene)|ensembl:ENST00000646651(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YH2|rcsb pdb:4CCG|rcsb pdb:5NGZ|rcsb pdb:5OJJ|rcsb pdb:6R75|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|reactome:R-HSA-8866652	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:/w+L/oINlKM5ZSm1OkI+R+8PxXg9606	rogid:hKFqKCWzIhcGshB1ut+mTTSwxbQ9606	intact-crc:B2FEF41319D164AF|rigid:iPM68nurnXsCkkDwk0tUUB9Tcn8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q9UKV5	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341852|imex:IM-11696-294	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	intact-crc:B321FC6FCE2EFDFC|rigid:V33uAZcS6/T6SiltLEB4QE/ug70	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NPD8	uniprotkb:Q7Z419	intact:EBI-2130165|uniprotkb:Q2TU36|ensembl:ENSP00000494957	intact:EBI-2129982|uniprotkb:B3KUA8|uniprotkb:Q5TB85|uniprotkb:Q6P4Q0|uniprotkb:Q8N3R7|uniprotkb:Q9BX38|uniprotkb:B4DZI2|ensembl:ENSP00000259939	psi-mi:ube2t_human(display_long)|uniprotkb:UBE2T(gene name)|psi-mi:UBE2T(display_short)|uniprotkb:Ubiquitin-protein ligase T(gene name synonym)|uniprotkb:Ubiquitin carrier protein T(gene name synonym)|uniprotkb:HSPC150(orf name)|uniprotkb:Cell proliferation-inducing gene 50 protein(gene name synonym)|uniprotkb:PIG50(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme T(gene name synonym)	psi-mi:r144b_human(display_long)|uniprotkb:RNF144B(gene name)|psi-mi:RNF144B(display_short)|uniprotkb:IBRDC2(gene name synonym)|uniprotkb:P53RFP(gene name synonym)|uniprotkb:RING finger protein 144B(gene name synonym)|uniprotkb:IBR domain-containing protein 2(gene name synonym)|uniprotkb:p53-inducible RING finger protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341846|imex:IM-11696-292	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054895.1|refseq:NP_001297255.1|dip:DIP-52740N|ensembl:ENSG00000077152(gene)|ensembl:ENST00000646651(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YH2|rcsb pdb:4CCG|rcsb pdb:5NGZ|rcsb pdb:5OJJ|rcsb pdb:6R75|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|reactome:R-HSA-8866652	refseq:NP_877434.2|dip:DIP-43771N|ensembl:ENSG00000137393(gene)|ensembl:ENST00000259939(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:hKFqKCWzIhcGshB1ut+mTTSwxbQ9606	rogid:Ep53jYpmEeClpBZYNkPKrQgy/0A9606	intact-crc:AFF1EF07C6819E95|rigid:2UGfkJ5axAMVJ7mELS40pNEMf3I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:Q9Y385	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-988826|uniprotkb:Q5W0N4|uniprotkb:Q9BZ32|uniprotkb:Q9NQL3|uniprotkb:Q9NY66|uniprotkb:Q9P011|uniprotkb:Q9P0S0|uniprotkb:Q9UF10|ensembl:ENSP00000451261|uniprotkb:A8K3F9|uniprotkb:Q53F25	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:ub2j1_human(display_long)|uniprotkb:Non-canonical ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:Yeast ubiquitin-conjugating enzyme UBC6 homolog E(gene name synonym)|uniprotkb:UBE2J1(gene name)|psi-mi:UBE2J1(display_short)|uniprotkb:NCUBE1(gene name synonym)|uniprotkb:CGI-76(orf name)|uniprotkb:HSPC153(orf name)|uniprotkb:HSPC205(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme J1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341849|imex:IM-11696-293	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|reactome:R-HSA-983168|ensembl:ENSG00000198833(gene)|ensembl:ENST00000435041(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007286"(spermatid development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_057105.2|dip:DIP-45598N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:nc3+V3Qxy1ZDhTWgTPLakJukxPM9606	intact-crc:84F9C0D024CD78EF|rigid:5U36rVWUPL8czTrWlgT0nTtB7yU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:Q9Y2X8	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341855|imex:IM-11696-295	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:973112085E33031A|rigid:tHGxdgQFSBoUIs7wb3g5DYo/M7g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q06587	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341858|imex:IM-11696-296	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606	intact-crc:3A7271672BBCB445|rigid:7LxPoDSPSrPaAOrejemaF5i+Io8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P78317	uniprotkb:Q9Y2X8	intact:EBI-2340927|uniprotkb:Q49AR8|uniprotkb:B2R6D6|uniprotkb:D6RF58|intact:EBI-28970119|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:rnf4_human(display_long)|uniprotkb:SNURF(gene name synonym)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:RNF4(gene name)|psi-mi:RNF4(display_short)|uniprotkb:RES4-26(orf name)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341861|imex:IM-11696-297	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171938.1|refseq:NP_001171939.1|refseq:NP_002929.1|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503|ensembl:ENST00000511859|ensembl:ENSP00000426615|ensembl:ENST00000541204|ensembl:ENSP00000446369|ensembl:ENSG00000063978(gene)|ensembl:ENST00000314289(transcript)|ensembl:ENST00000506706(transcript)|ensembl:ENST00000511600(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|go:"GO:1990752"(microtubule end)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|mint:P78317|rcsb pdb:2EA6|rcsb pdb:2XEU|rcsb pdb:4PPE|reactome:R-HSA-5693607|reactome:R-HSA-983168	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Yhu2iAaNQYcfGdYohDPBdhMFEpc9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:94BD4C553380FF36|rigid:t/ZryPAdX0Q1L/2gNiCy5ViN9IU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14258	uniprotkb:Q9Y2X8	intact:EBI-2341129|intact:EBI-28973868|ensembl:ENSP00000323889|ensembl:ENSP00000445961	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:tri25_human(display_long)|uniprotkb:TRIM25(gene name)|psi-mi:TRIM25(display_short)|uniprotkb:EFP(gene name synonym)|uniprotkb:RNF147(gene name synonym)|uniprotkb:ZNF147(gene name synonym)|uniprotkb:Zinc finger protein 147(gene name synonym)|uniprotkb:Estrogen-responsive finger protein(gene name synonym)|uniprotkb:RING finger protein 147(gene name synonym)|uniprotkb:Ubiquitin/ISG15-conjugating enzyme TRIM25(gene name synonym)|uniprotkb:Tripartite motif-containing protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM25(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341870|imex:IM-11696-300	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000323889|ensembl:ENSP00000445961|refseq:NP_005073.2|ensembl:ENSG00000121060(gene)|ensembl:ENST00000316881(transcript)|ensembl:ENST00000537230(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016604"(nuclear body)|go:"GO:0016874"(ligase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033280"(response to vitamin D)|go:"GO:0039552"(RIG-I binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043627"(response to estrogen)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|go:"GO:1902187"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042753|interpro:IPR043136|mint:Q14258|rcsb pdb:4CFG|rcsb pdb:4LTB|rcsb pdb:5EYA|rcsb pdb:5FER|rcsb pdb:5NT1|rcsb pdb:5NT2|rcsb pdb:6FLM|rcsb pdb:6FLN|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-5689896|reactome:R-HSA-877300|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:NhFfC0IxHvxPIt2YnKCPsPKuiQA9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:4E629B408342C676|rigid:eU6OsXu5vJx7sFwoNuUitYBQe8A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q9Y4K3	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|ensembl:ENSP00000337853|ensembl:ENSP00000433623|uniprotkb:D3DR16	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341864|imex:IM-11696-298	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_004611.1|refseq:NP_665802.1|ensembl:ENSG00000175104(gene)|ensembl:ENST00000348124(transcript)|ensembl:ENST00000526995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|go:"GO:0070534"(protein K63-linked ubiquitination)|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|go:"GO:0070555"(response to interleukin-1)|rcsb pdb:7L3L|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|go:"GO:0071222"(cellular response to lipopolysaccharide)|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-975871|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|dip:DIP-27515N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606	intact-crc:2C18B51E6D5B9697|rigid:gbSSGZgVoK8ZpLA6avDRUV27C9g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13064	uniprotkb:Q9Y2X8	intact:EBI-2340269|ensembl:ENSP00000313881	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341867|imex:IM-11696-299	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:15E05508EF78736D|rigid:+tYL3zGMIS2YSiyYe//NruQIklc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBF6	uniprotkb:Q9Y2X8	intact:EBI-398632|uniprotkb:Q9BXN8|uniprotkb:Q9Y5M7|uniprotkb:A8MTB5|uniprotkb:A8K1H9|uniprotkb:D3DNF7|uniprotkb:D3DNF8|uniprotkb:C9JYL3|ensembl:ENSP00000273480	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:rbx2_human(display_long)|uniprotkb:RNF7(gene name)|psi-mi:RNF7(display_short)|uniprotkb:RBX2(gene name synonym)|uniprotkb:ROC2(gene name synonym)|uniprotkb:SAG(gene name synonym)|uniprotkb:RING finger protein 7(gene name synonym)|uniprotkb:Regulator of cullins 2(gene name synonym)|uniprotkb:CKII beta-binding protein 1(gene name synonym)|uniprotkb:Sensitive to apoptosis gene protein(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341873|imex:IM-11696-301	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055060.1|refseq:NP_899060.1|refseq:NP_001188299.1|ensembl:ENSG00000114125(gene)|ensembl:ENST00000273480(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045116"(protein neddylation)|go:"GO:0051775"(response to redox state)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|rcsb pdb:2ECL|reactome:R-HSA-8951664|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:FNop0ozErv05khKc5si7nNH/Hww9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:619CA256EB904D07|rigid:GfArkngrBsEFM8o9qjfWJ5aQPuQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:O95376	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-711158|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9|ensembl:ENSP00000348769|ensembl:ENSP00000403222	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341876|imex:IM-11696-302	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|ensembl:ENSG00000177479(gene)|ensembl:ENST00000356401(transcript)|ensembl:ENST00000449376(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|refseq:XP_016861020.1|refseq:XP_016861021.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	intact-crc:5A87BE1F9B669673|rigid:laATiBrVmal6o3+subYOB1fkRtI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q9UPQ4	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-2130401|uniprotkb:Q86XQ0|uniprotkb:Q8WVA4|ensembl:ENSP00000301924	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:tri35_human(display_long)|uniprotkb:TRIM35(gene name)|psi-mi:TRIM35(display_short)|uniprotkb:HLS5(gene name synonym)|uniprotkb:KIAA1098(gene name synonym)|uniprotkb:Hemopoietic lineage switch protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341885|imex:IM-11696-305	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_741983.2|ensembl:ENSG00000104228(gene)|ensembl:ENST00000305364(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR043136|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:VlC2XEURqN7nMIfIns2E0QVsL7k9606	intact-crc:5A729B35742696CE|rigid:NxK3b2joRUDTZXuuJLkXWWmnYl0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q9BYM8	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341879|imex:IM-11696-303	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_006453.1|refseq:NP_112506.2|ensembl:ENSG00000125826(gene)|ensembl:ENST00000356286(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR026261|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|dip:DIP-47737N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606	intact-crc:7EA724B21F619508|rigid:xl0YBDFDaEEUW/pdGRfi01ZXoZY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZY9	uniprotkb:Q9Y2X8	intact:EBI-747544|uniprotkb:Q53H52|uniprotkb:Q5RI37|uniprotkb:Q5SRJ7|uniprotkb:Q5SRJ8|uniprotkb:Q5SS28|uniprotkb:Q96AK4|uniprotkb:Q96AP8|uniprotkb:Q99579|uniprotkb:Q9BZY8|uniprotkb:A6NLX6|uniprotkb:A9R9Q4|ensembl:ENSP00000350182|ensembl:ENSP00000365924|ensembl:ENSP00000390551|ensembl:ENSP00000391685|ensembl:ENSP00000398677|ensembl:ENSP00000409501	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:tri31_human(display_long)|uniprotkb:TRIM31(gene name)|psi-mi:TRIM31(display_short)|uniprotkb:C6orf13(gene name synonym)|uniprotkb:RNF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 31(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM31(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341882|imex:IM-11696-304	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008959.3|ensembl:ENSG00000137397(gene)|ensembl:ENSG00000204616(gene)|ensembl:ENSG00000223531(gene)|ensembl:ENSG00000224168(gene)|ensembl:ENSG00000225130(gene)|ensembl:ENSG00000233573(gene)|ensembl:ENST00000357569(transcript)|ensembl:ENST00000376734(transcript)|ensembl:ENST00000433864(transcript)|ensembl:ENST00000445679(transcript)|ensembl:ENST00000449412(transcript)|ensembl:ENST00000453266(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR020457|rcsb pdb:2YSJ|rcsb pdb:2YSL|reactome:R-HSA-877300	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:f7qMSpsjq1gDv+rl2o2BWpXhvKw9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:FFF91C99E1D74E31|rigid:isq2W3UZHdTeFbCBuA5cIStVQfU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:O60291	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-2129851|uniprotkb:A4URL3|uniprotkb:A4URL4|uniprotkb:Q86W76|intact:EBI-28986785|ensembl:ENSP00000382487	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:mgrn1_human(display_long)|uniprotkb:MGRN1(gene name)|psi-mi:MGRN1(display_short)|uniprotkb:KIAA0544(gene name synonym)|uniprotkb:RNF156(gene name synonym)|uniprotkb:Mahogunin RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 156(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MGRN1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341888|imex:IM-11696-306	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_001135761.2|refseq:NP_001135762.1|refseq:NP_001135763.2|refseq:NP_056061.1|ensembl:ENST00000262370|ensembl:ENSP00000262370|ensembl:ENSP00000382487|ensembl:ENST00000415496|ensembl:ENSP00000393311|ensembl:ENST00000586183|ensembl:ENSP00000465860|ensembl:ENST00000588994|ensembl:ENSP00000468819|refseq:XP_005255277.1|refseq:XP_005255278.1|ensembl:ENSG00000102858(gene)|ensembl:ENST00000399577(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:UuLoCnlkpTBs/rmGgpQvgiMNuNE9606	intact-crc:F50EF6505CBE2576|rigid:jQ+em71hgpQqWLRkAu0f+b+ef3w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q9C040	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341891|imex:IM-11696-307	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	intact-crc:7A051C89617D2140|rigid:7HoYY3S55UGMWE+ufBBVKPx6bZ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96PM5	uniprotkb:Q9Y2X8	intact:EBI-947779|uniprotkb:C7E542|uniprotkb:C7E543|uniprotkb:Q96PR5|uniprotkb:C7E541|uniprotkb:Q59GN7|uniprotkb:Q86X26|uniprotkb:B3KRG3|uniprotkb:E7EMC8|uniprotkb:E7ETW5|uniprotkb:J3KPI0|uniprotkb:D3YRV2|uniprotkb:Q2KN33|ensembl:ENSP00000321239	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:zn363_human(display_long)|uniprotkb:Zinc finger protein 363(gene name synonym)|uniprotkb:CH-rich-interacting match with PLAG1(gene name synonym)|uniprotkb:Androgen receptor N-terminal-interacting protein(gene name synonym)|uniprotkb:p53-induced RING-H2 protein(gene name synonym)|uniprotkb:RING finger protein 199(gene name synonym)|uniprotkb:RCHY1(gene name)|psi-mi:RCHY1(display_short)|uniprotkb:ARNIP(gene name synonym)|uniprotkb:CHIMP(gene name synonym)|uniprotkb:ZNF363(gene name synonym)|uniprotkb:PIRH2(gene name synonym)|uniprotkb:RNF199(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase Pirh2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RCHY1(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341894|imex:IM-11696-308	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009922.1|refseq:NP_056251.2|refseq:NP_001265465.1|refseq:NP_001265466.1|refseq:NP_001265467.1|dip:DIP-43981N|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070987"(error-free translesion synthesis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008913(Zinc finger, CHY-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017921|interpro:IPR037274|interpro:IPR037275|interpro:IPR039512|mint:Q96PM5|rcsb pdb:2JRJ|rcsb pdb:2K2C|rcsb pdb:2K2D|reactome:R-HSA-110320|reactome:R-HSA-983168|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENSG00000163743(gene)|ensembl:ENST00000324439(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002039"(p53 binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:3khPuhFXlOrWR6KjF+9av4mJAMQ9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:534B578AFA2EFB2E|rigid:sSfn4bpTbpF24cwpVjBhcipjcnU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NZS9	uniprotkb:Q9Y2X8	intact:EBI-2130199|uniprotkb:A8K4Z9|uniprotkb:D3DUG8|uniprotkb:B4DUT0|ensembl:ENSP00000261658|ensembl:ENSP00000478190	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:bfar_human(display_long)|uniprotkb:BFAR(gene name)|psi-mi:BFAR(display_short)|uniprotkb:BAR(gene name synonym)|uniprotkb:RNF47(gene name synonym)|uniprotkb:RING finger protein 47(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341903|imex:IM-11696-311	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057645.1|refseq:XP_005255407.1|ensembl:ENSG00000103429(gene)|ensembl:ENSG00000275618(gene)|ensembl:ENST00000261658(transcript)|ensembl:ENST00000619034(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017907	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:XDPFsRmdbch1NXffLOcE0lVrtRo9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:692015BAC5402385|rigid:MZ4VSCtIb84/1LAXGa9ZcP3FEtY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y577	uniprotkb:Q9Y2X8	intact:EBI-743894|uniprotkb:B4DVJ2|uniprotkb:Q5VST8|ensembl:ENSP00000295033|ensembl:ENSP00000355658|ensembl:ENSP00000355659|ensembl:ENSP00000493891|ensembl:ENSP00000495842|ensembl:ENSP00000496098	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:tri17_human(display_long)|uniprotkb:Testis RING finger protein(gene name synonym)|uniprotkb:RING finger protein 16(gene name synonym)|uniprotkb:TRIM17(gene name)|psi-mi:TRIM17(display_short)|uniprotkb:RBCC(gene name synonym)|uniprotkb:RNF16(gene name synonym)|uniprotkb:TERF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 17(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM17(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341897|imex:IM-11696-309	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162931(gene)|ensembl:ENSG00000285344(gene)|refseq:NP_001020111.1|refseq:NP_001128327.1|refseq:NP_057186.1|refseq:XP_011542511.1|refseq:XP_011542512.1|refseq:XP_006711842.1|ensembl:ENST00000295033(transcript)|ensembl:ENST00000366697(transcript)|ensembl:ENST00000366698(transcript)|ensembl:ENST00000645562(transcript)|ensembl:ENST00000645958(transcript)|ensembl:ENST00000647385(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045087"(innate immune response)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032918|interpro:IPR035687|interpro:IPR043136|reactome:R-HSA-877300	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:pXiCDkeNMtq9icQduH4MSCM6vSQ9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:66C45C2F006B8A9F|rigid:PMG13d7Bup0jJWIL0jgUjKHpVTU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVW2	uniprotkb:Q9Y2X8	intact:EBI-1996544|uniprotkb:Q9Y598|uniprotkb:Q96D38|uniprotkb:D3DTE0|uniprotkb:B2RBQ1|ensembl:ENSP00000253571|ensembl:ENSP00000328059	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:rnf12_human(display_long)|uniprotkb:RLIM(gene name)|psi-mi:RLIM(display_short)|uniprotkb:RNF12(gene name synonym)|uniprotkb:RING finger protein 12(gene name synonym)|uniprotkb:LIM domain-interacting RING finger protein(gene name synonym)|uniprotkb:RING finger LIM domain-binding protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-43(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RLIM(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341900|imex:IM-11696-310	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057204.2|refseq:NP_899196.1|ensembl:ENSG00000131263(gene)|ensembl:ENST00000332687(transcript)|ensembl:ENST00000349225(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060816"(random inactivation of X chromosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900095"(regulation of dosage compensation by inactivation of X chromosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NVW2|rcsb pdb:6W7Z|rcsb pdb:6W9A|rcsb pdb:6W9D|reactome:R-HSA-983168	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:jEHiOt7hjZc5HU6E/XQGE7zdZbw9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:9029365A522D972F|rigid:Xep6neWUUEYdP3130F9c52QfVi8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6PCD5	uniprotkb:Q9Y2X8	intact:EBI-2129159|uniprotkb:Q9H9Q3|uniprotkb:Q9NVT4|uniprotkb:Q5XKR3|uniprotkb:A8K585|uniprotkb:B2RE35|uniprotkb:D3DUJ8|ensembl:ENSP00000354361|ensembl:ENSP00000460049	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:rfwd3_human(display_long)|uniprotkb:RFWD3(gene name)|psi-mi:RFWD3(display_short)|uniprotkb:RING finger and WD repeat domain-containing protein 3(gene name synonym)|uniprotkb:RNF201(gene name synonym)|uniprotkb:RING finger protein 201(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341906|imex:IM-11696-312	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011521493.1|refseq:NP_060594.3|refseq:XP_016878880.1|refseq:XP_005256078.1|refseq:XP_005256079.1|dip:DIP-52688N|ensembl:ENSG00000168411(gene)|ensembl:ENST00000361070(transcript)|ensembl:ENST00000571750(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031297"(replication fork processing)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037381|rcsb pdb:6CVZ	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:r7gkMbkS0GKPVn9riLPR34KFaKk9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:0B40BC552C48FF41|rigid:YLgCINVbiYhsIb6klBz0Etapp9c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q96EP1	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-718923|uniprotkb:A6NEN5|uniprotkb:Q96SL3|uniprotkb:Q9NRT4|uniprotkb:Q9NT32|uniprotkb:Q9NVD5|uniprotkb:B4DZ77|uniprotkb:B4E2L6|ensembl:ENSP00000392395	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:chfr_human(display_long)|uniprotkb:Checkpoint with forkhead and RING finger domains protein(gene name synonym)|uniprotkb:RING finger protein 196(gene name synonym)|uniprotkb:CHFR(gene name)|psi-mi:CHFR(display_short)|uniprotkb:RNF196(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHFR(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341909|imex:IM-11696-313	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_001154816.1|refseq:NP_001154817.1|refseq:NP_001154818.1|refseq:NP_001154819.1|refseq:NP_060693.2|ensembl:ENSG00000072609(gene)|ensembl:ENST00000432561(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR019406|interpro:IPR040909|rcsb pdb:1LGP|rcsb pdb:1LGQ|rcsb pdb:2XOC|rcsb pdb:2XOY|rcsb pdb:2XOZ|rcsb pdb:2XP0|dip:DIP-40098N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid://FU72n6rmuPAu+Fjm377S4nEjw9606	intact-crc:161FC6D632982105|rigid:mWWrdCjcBQGk6xS9PU95xx7Andw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6UWE0	uniprotkb:Q9Y2X8	intact:EBI-720984|uniprotkb:Q5VVV0|uniprotkb:Q8NB40|uniprotkb:Q96GT5|uniprotkb:Q96MX5|uniprotkb:Q96MZ7|ensembl:ENSP00000300417|ensembl:ENSP00000322937|ensembl:ENSP00000362419|ensembl:ENSP00000502167	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:lrsm1_human(display_long)|uniprotkb:Leucine-rich repeat and sterile alpha motif-containing protein 1(gene name synonym)|uniprotkb:Tsg101-associated ligase(gene name synonym)|uniprotkb:LRSAM1(gene name)|psi-mi:LRSAM1(display_short)|uniprotkb:TAL(gene name synonym)|uniprotkb:UNQ6496/PRO21356(orf name)|uniprotkb:RING-type E3 ubiquitin transferase LRSAM1(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341918|imex:IM-11696-316	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005373.1|refseq:NP_001005374.1|refseq:NP_001177652.1|refseq:NP_612370.3|refseq:XP_016870772.1|ensembl:ENSG00000148356(gene)|ensembl:ENST00000300417(transcript)|ensembl:ENST00000323301(transcript)|ensembl:ENST00000373322(transcript)|ensembl:ENST00000675448(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0046755"(viral budding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032675|mint:Q6UWE0|reactome:R-HSA-983168	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:qkwPqOsfNjZBB2Xp6YAA9FbEZxM9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:E7460892F84B253C|rigid:4OVCksbXEMuhpzWF6MVyQy0vOc4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q6Q0C0	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-307556|uniprotkb:Q9H073|ensembl:ENSP00000318944	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:traf7_human(display_long)|uniprotkb:TRAF7(gene name)|psi-mi:TRAF7(display_short)|uniprotkb:TNF receptor-associated factor 7(gene name synonym)|uniprotkb:RING finger and WD repeat-containing protein 1(gene name synonym)|uniprotkb:RING finger protein 119(gene name synonym)|uniprotkb:RFWD1(gene name synonym)|uniprotkb:RNF119(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341912|imex:IM-11696-314	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_115647.2|ensembl:ENSG00000131653(gene)|ensembl:ENST00000326181(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017907|interpro:IPR019775|interpro:IPR020472|interpro:IPR027370|interpro:IPR036322|mint:Q6Q0C0|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:46dtsS1OairncB0fnINSW1aY2789606	intact-crc:298CB95745E293E6|rigid:mJzBCLIqDrEVrzO7edAbqrFOPHE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q9C035	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-924214|uniprotkb:Q2MLV4|uniprotkb:Q2MLV8|uniprotkb:Q2MLV9|uniprotkb:Q2MLW1|uniprotkb:Q2MLW3|uniprotkb:Q2MLW4|uniprotkb:A6NGQ1|uniprotkb:Q2MLW6|uniprotkb:Q2MLW7|uniprotkb:Q2MLX1|uniprotkb:Q2MLX2|uniprotkb:Q2MLX3|uniprotkb:Q2MLX5|uniprotkb:Q2MLY3|uniprotkb:Q2MLY4|uniprotkb:Q2V6Q6|uniprotkb:Q6GX26|uniprotkb:Q8WU46|uniprotkb:Q96SR5|uniprotkb:Q9C031|uniprotkb:Q9C032|uniprotkb:Q9C033|uniprotkb:Q9C034|uniprotkb:A8WFA8|uniprotkb:D3DQS8|uniprotkb:D3DQS9|uniprotkb:G3GJY1|ensembl:ENSP00000369373|ensembl:ENSP00000507420	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:trim5_human(display_long)|uniprotkb:TRIM5(gene name)|psi-mi:TRIM5(display_short)|uniprotkb:RNF88(gene name synonym)|uniprotkb:RING finger protein 88(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341915|imex:IM-11696-315	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_149023.2|refseq:NP_149083.2|refseq:NP_149084.2|refseq:XP_011518729.1|refseq:XP_005253240.1|refseq:XP_005253241.1|ensembl:ENSG00000132256(gene)|ensembl:ENST00000380034(transcript)|ensembl:ENST00000684655(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031664"(regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR043136|rcsb pdb:2ECV|rcsb pdb:2YRG|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:t0YqhaJC8oQcwot7oks1LgMxdNc9606	intact-crc:B2E69168BA10968A|rigid:2sgTFtr8oYZnlOPhAvGtID9sIXE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q9H0F5	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-2341200|uniprotkb:Q8N0Y0|uniprotkb:A6PVP9|uniprotkb:B1AM82|uniprotkb:Q7LB33|ensembl:ENSP00000259605|uniprotkb:B1AM81|uniprotkb:B3KSG4|uniprotkb:E7EVL3|uniprotkb:Q9H748	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:rnf38_human(display_long)|uniprotkb:RING finger protein 38(gene name synonym)|uniprotkb:RNF38(gene name)|psi-mi:RNF38(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF38(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341927|imex:IM-11696-319	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:XP_011516014.1|refseq:XP_011516015.1|refseq:XP_006716784.1|refseq:NP_073618.3|refseq:NP_919309.1|refseq:NP_919310.1|refseq:NP_919311.1|refseq:NP_919313.1|ensembl:ENSG00000137075(gene)|ensembl:ENST00000259605(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008584"(male gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|go:"GO:0036126"(sperm flagellum)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9H0F5|rcsb pdb:1X4J|rcsb pdb:4V3K|rcsb pdb:4V3L|ensembl:ENSP00000259605|ensembl:ENST00000350199|ensembl:ENSP00000343947|ensembl:ENST00000353739|ensembl:ENSP00000335239|ensembl:ENST00000357058|ensembl:ENSP00000349566|ensembl:ENST00000377877|ensembl:ENSP00000367109|ensembl:ENST00000377885|ensembl:ENSP00000367117|ensembl:ENST00000611646|ensembl:ENSP00000483536|refseq:XP_005251423.1|refseq:XP_005251424.1|refseq:XP_005251425.1|refseq:XP_016869784.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:leJgsTFAtsRhHPh44pbrpk1wkDo9606	intact-crc:AF536BFC7D0B969A|rigid:CFhuadIIJbvEIJxgkQD8gK9Rhq0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96P09	uniprotkb:Q9Y2X8	intact:EBI-2341055|uniprotkb:Q96RW5|uniprotkb:Q6IPY1	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	psi-mi:birc8_human(display_long)|uniprotkb:BIRC8(gene name)|psi-mi:BIRC8(display_short)|uniprotkb:ILP2(gene name synonym)|uniprotkb:Inhibitor of apoptosis-like protein 2(gene name synonym)|uniprotkb:Testis-specific inhibitor of apoptosis(gene name synonym)	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341921|imex:IM-11696-317	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR042579|refseq:NP_203127.3|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:1XB0|rcsb pdb:1XB1|interpro:IPR011029(DEATH-like)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dNa54zbu4SMSRJ8FXGBLuqGJ0qo9606	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	intact-crc:5457235121434E27|rigid:EDwxSrNEyH1ft4J0mtaUQXmGmXE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2X8	uniprotkb:Q86UD3	intact:EBI-745527|ensembl:ENSP00000222402|uniprotkb:A4D1V0	intact:EBI-2341065|uniprotkb:A8K264|uniprotkb:B9EJE7|ensembl:ENSP00000309141	psi-mi:ub2d4_human(display_long)|uniprotkb:Ubiquitin-protein ligase D4(gene name synonym)|uniprotkb:Ubiquitin carrier protein D4(gene name synonym)|uniprotkb:HBUCE1(gene name synonym)|uniprotkb:UBE2D4(gene name)|psi-mi:UBE2D4(display_short)|uniprotkb:UBCH5D(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D4(gene name synonym)	psi-mi:marh3_human(display_long)|uniprotkb:MARCHF3(gene name)|psi-mi:MARCHF3(display_short)|uniprotkb:MARCH3(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 3(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein III(gene name synonym)|uniprotkb:RING finger protein 173(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF3(gene name synonym)|uniprotkb:RNF173(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341924|imex:IM-11696-318	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057067.1|ensembl:ENSG00000078967(gene)|ensembl:ENST00000222402(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-983168	refseq:NP_848545.1|ensembl:ENSG00000173926(gene)|ensembl:ENST00000308660(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xc+Dyvh3gHK14B0RxgVqoToxbTI9606	rogid:uv/JcWUoL549NACFaOUs/oLdHuI9606	intact-crc:E43B5569535F3D17|rigid:1W1+RzUylXezCNSB0IojUSJsznQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q712K3	uniprotkb:Q9ULV8	intact:EBI-2340879|uniprotkb:Q9NX64|uniprotkb:D3DRL5|ensembl:ENSP00000263228	intact:EBI-2341018|uniprotkb:Q9Y5Z3|uniprotkb:Q8N1E5|uniprotkb:Q9Y5Z2|intact:EBI-28975910|ensembl:ENSP00000494162	psi-mi:ub2r2_human(display_long)|uniprotkb:UBE2R2(gene name)|psi-mi:UBE2R2(display_short)|uniprotkb:CDC34B(gene name synonym)|uniprotkb:UBC3B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase R2(gene name synonym)|uniprotkb:Ubiquitin carrier protein R2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-CDC34B(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme R2(gene name synonym)	psi-mi:cblc_human(display_long)|uniprotkb:CBLC(gene name)|psi-mi:CBLC(display_short)|uniprotkb:CBL3(gene name synonym)|uniprotkb:RNF57(gene name synonym)|uniprotkb:SH3-binding protein CBL-C(gene name synonym)|uniprotkb:SH3-binding protein CBL-3(gene name synonym)|uniprotkb:RING finger protein 57(gene name synonym)|uniprotkb:Signal transduction protein CBL-C(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CBL-C(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341936|imex:IM-11696-322	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060281.2|ensembl:ENSG00000107341(gene)|ensembl:ENST00000263228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:6NYO|reactome:R-HSA-8866652|reactome:R-HSA-983168	ensembl:ENST00000341505|ensembl:ENSP00000340250|ensembl:ENSP00000494162|refseq:NP_001124324.1|refseq:NP_036248.3|ensembl:ENSG00000142273(gene)|ensembl:ENST00000647358(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|rcsb pdb:3OP0|rcsb pdb:3VRN|rcsb pdb:3VRO|rcsb pdb:3VRP|rcsb pdb:3VRQ|rcsb pdb:3VRR	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:fFTiply+7nUD6veFiQW5xcNmRrE9606	rogid:syzTzR6RGJzLv2EpDirSrli4ghs9606	intact-crc:0917FACF66A6CE9C|rigid:Nl2LzpoddO+Nu1c4rBD6ztpDgos	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q712K3	uniprotkb:Q86Y13	intact:EBI-2340879|uniprotkb:Q9NX64|uniprotkb:D3DRL5|ensembl:ENSP00000263228	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:ub2r2_human(display_long)|uniprotkb:UBE2R2(gene name)|psi-mi:UBE2R2(display_short)|uniprotkb:CDC34B(gene name synonym)|uniprotkb:UBC3B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase R2(gene name synonym)|uniprotkb:Ubiquitin carrier protein R2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-CDC34B(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme R2(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341930|imex:IM-11696-320	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060281.2|ensembl:ENSG00000107341(gene)|ensembl:ENST00000263228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:6NYO|reactome:R-HSA-8866652|reactome:R-HSA-983168	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:fFTiply+7nUD6veFiQW5xcNmRrE9606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:B5934C32B17629A3|rigid:Mm8siKsnSICmjoHWMpSpWKsaGyQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95376	uniprotkb:Q712K3	intact:EBI-711158|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9|ensembl:ENSP00000348769|ensembl:ENSP00000403222	intact:EBI-2340879|uniprotkb:Q9NX64|uniprotkb:D3DRL5|ensembl:ENSP00000263228	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym)	psi-mi:ub2r2_human(display_long)|uniprotkb:UBE2R2(gene name)|psi-mi:UBE2R2(display_short)|uniprotkb:CDC34B(gene name synonym)|uniprotkb:UBC3B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase R2(gene name synonym)|uniprotkb:Ubiquitin carrier protein R2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-CDC34B(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme R2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341933|imex:IM-11696-321	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|ensembl:ENSG00000177479(gene)|ensembl:ENST00000356401(transcript)|ensembl:ENST00000449376(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|refseq:XP_016861020.1|refseq:XP_016861021.1	refseq:NP_060281.2|ensembl:ENSG00000107341(gene)|ensembl:ENST00000263228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:6NYO|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	rogid:fFTiply+7nUD6veFiQW5xcNmRrE9606	intact-crc:B78AB339A2B8FB7A|rigid:WrFX4q9sULgsWErOK8lT1Zq5uVs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:Q96B02	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341945|imex:IM-11696-325	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:890CC5B9730BCF51|rigid:2Ig3Vo9IvPHbcI0qNcBxgPlqFAg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TDB6	uniprotkb:Q712K3	intact:EBI-2340392|uniprotkb:Q5MJP7|uniprotkb:Q53ZZ3|uniprotkb:B3KWH6|ensembl:ENSP00000296161	intact:EBI-2340879|uniprotkb:Q9NX64|uniprotkb:D3DRL5|ensembl:ENSP00000263228	psi-mi:dtx3l_human(display_long)|uniprotkb:DTX3L(gene name)|psi-mi:DTX3L(display_short)|uniprotkb:BBAP(gene name synonym)|uniprotkb:B-lymphoma- and BAL-associated protein(gene name synonym)|uniprotkb:Rhysin-2(gene name synonym)|uniprotkb:Protein deltex-3-like(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3L(gene name synonym)	psi-mi:ub2r2_human(display_long)|uniprotkb:UBE2R2(gene name)|psi-mi:UBE2R2(display_short)|uniprotkb:CDC34B(gene name synonym)|uniprotkb:UBC3B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase R2(gene name synonym)|uniprotkb:Ubiquitin carrier protein R2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-CDC34B(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme R2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341939|imex:IM-11696-323	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612144.1|ensembl:ENSG00000163840(gene)|ensembl:ENST00000296161(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0015031"(protein transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:2000646"(positive regulation of receptor catabolic process)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|interpro:IPR042843|rcsb pdb:3PG6|reactome:R-HSA-983168	refseq:NP_060281.2|ensembl:ENSG00000107341(gene)|ensembl:ENST00000263228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:6NYO|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:d2ctDfd7pj1wRA3HxmyWJ5nL19Y9606	rogid:fFTiply+7nUD6veFiQW5xcNmRrE9606	intact-crc:9EA6A625EE57DCFE|rigid:v9zS6kuf5GX4gD5np64ugPh0+5Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P98170	uniprotkb:Q96B02	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341942|imex:IM-11696-324	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:FD72D21DE0C9F17A|rigid:mumMLfoMzPFJhqa9wEFU353rkZM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q99496	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341948|imex:IM-11696-326	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	intact-crc:DDF2F65DC635F9D9|rigid:GYmO3sm5e/gwibhcoq5tJZZ37aI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:P78317	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-2340927|uniprotkb:Q49AR8|uniprotkb:B2R6D6|uniprotkb:D6RF58|intact:EBI-28970119|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:rnf4_human(display_long)|uniprotkb:SNURF(gene name synonym)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:RNF4(gene name)|psi-mi:RNF4(display_short)|uniprotkb:RES4-26(orf name)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341951|imex:IM-11696-493	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_001171938.1|refseq:NP_001171939.1|refseq:NP_002929.1|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503|ensembl:ENST00000511859|ensembl:ENSP00000426615|ensembl:ENST00000541204|ensembl:ENSP00000446369|ensembl:ENSG00000063978(gene)|ensembl:ENST00000314289(transcript)|ensembl:ENST00000506706(transcript)|ensembl:ENST00000511600(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|go:"GO:1990752"(microtubule end)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|mint:P78317|rcsb pdb:2EA6|rcsb pdb:2XEU|rcsb pdb:4PPE|reactome:R-HSA-5693607|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:Yhu2iAaNQYcfGdYohDPBdhMFEpc9606	intact-crc:8A809BE41EB8337D|rigid:OGIg0poDUUCDMkrBW8u4DFRkX+w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5U6	uniprotkb:Q96B02	intact:EBI-714023|uniprotkb:Q92550|uniprotkb:Q9NPP8|uniprotkb:Q9ULW4|ensembl:ENSP00000322242	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:rnf10_human(display_long)|uniprotkb:RNF10(gene name)|psi-mi:RNF10(display_short)|uniprotkb:KIAA0262(gene name synonym)|uniprotkb:RIE2(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341960|imex:IM-11696-496	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055683.3|refseq:NP_001317403.1|ensembl:ENSG00000022840(gene)|ensembl:ENST00000325954(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039739|mint:Q8N5U6	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Bca0Ae456x1eCsdlduoCbn7coUQ9606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:ACB5259DDDD24692|rigid:qyzsW1Linsg28pLlUFStTPsvh7U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q99942	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341954|imex:IM-11696-494	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606	intact-crc:6A38AF52FDAEAEDD|rigid:sPPjfkdraOubJ1vJyCvx7Lfdmvo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13064	uniprotkb:Q96B02	intact:EBI-2340269|ensembl:ENSP00000313881	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341957|imex:IM-11696-495	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:0BDD82B9C240BF26|rigid:c/9kgKC4i2P0hJT3yPxfSvBE4Ck	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q9C040	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341969|imex:IM-11696-499	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	intact-crc:9DA6E0C2AEE10833|rigid:ZbJGZ1mvrKevYbVyh6f3N//Tcps	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZY9	uniprotkb:Q96B02	intact:EBI-747544|uniprotkb:Q53H52|uniprotkb:Q5RI37|uniprotkb:Q5SRJ7|uniprotkb:Q5SRJ8|uniprotkb:Q5SS28|uniprotkb:Q96AK4|uniprotkb:Q96AP8|uniprotkb:Q99579|uniprotkb:Q9BZY8|uniprotkb:A6NLX6|uniprotkb:A9R9Q4|ensembl:ENSP00000350182|ensembl:ENSP00000365924|ensembl:ENSP00000390551|ensembl:ENSP00000391685|ensembl:ENSP00000398677|ensembl:ENSP00000409501	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:tri31_human(display_long)|uniprotkb:TRIM31(gene name)|psi-mi:TRIM31(display_short)|uniprotkb:C6orf13(gene name synonym)|uniprotkb:RNF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 31(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM31(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341963|imex:IM-11696-497	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008959.3|ensembl:ENSG00000137397(gene)|ensembl:ENSG00000204616(gene)|ensembl:ENSG00000223531(gene)|ensembl:ENSG00000224168(gene)|ensembl:ENSG00000225130(gene)|ensembl:ENSG00000233573(gene)|ensembl:ENST00000357569(transcript)|ensembl:ENST00000376734(transcript)|ensembl:ENST00000433864(transcript)|ensembl:ENST00000445679(transcript)|ensembl:ENST00000449412(transcript)|ensembl:ENST00000453266(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR020457|rcsb pdb:2YSJ|rcsb pdb:2YSL|reactome:R-HSA-877300	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:f7qMSpsjq1gDv+rl2o2BWpXhvKw9606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:B5BEB4FCEEEBD0E5|rigid:ASFz9DDMVQz+bGj+hhGuKZB8l4s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:O60291	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-2129851|uniprotkb:A4URL3|uniprotkb:A4URL4|uniprotkb:Q86W76|intact:EBI-28986785|ensembl:ENSP00000382487	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:mgrn1_human(display_long)|uniprotkb:MGRN1(gene name)|psi-mi:MGRN1(display_short)|uniprotkb:KIAA0544(gene name synonym)|uniprotkb:RNF156(gene name synonym)|uniprotkb:Mahogunin RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 156(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MGRN1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341966|imex:IM-11696-498	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_001135761.2|refseq:NP_001135762.1|refseq:NP_001135763.2|refseq:NP_056061.1|ensembl:ENST00000262370|ensembl:ENSP00000262370|ensembl:ENSP00000382487|ensembl:ENST00000415496|ensembl:ENSP00000393311|ensembl:ENST00000586183|ensembl:ENSP00000465860|ensembl:ENST00000588994|ensembl:ENSP00000468819|refseq:XP_005255277.1|refseq:XP_005255278.1|ensembl:ENSG00000102858(gene)|ensembl:ENST00000399577(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:UuLoCnlkpTBs/rmGgpQvgiMNuNE9606	intact-crc:EB3321E17186E93D|rigid:tjX2ElC+AxNcZgBcx6GdHCEW5qA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NX47	uniprotkb:Q96B02	intact:EBI-2341610|ensembl:ENSP00000351813	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:marh5_human(display_long)|uniprotkb:MARCH5(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 5(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein V(gene name synonym)|uniprotkb:Mitochondrial ubiquitin ligase(gene name synonym)|uniprotkb:RING finger protein 153(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF5(gene name synonym)|uniprotkb:MARCHF5(gene name)|psi-mi:MARCHF5(display_short)|uniprotkb:RNF153(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341978|imex:IM-11696-502	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060294.1|ensembl:ENSG00000198060(gene)|ensembl:ENST00000358935(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051020"(GTPase binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090344"(negative regulation of cell aging)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NX47	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:/w+L/oINlKM5ZSm1OkI+R+8PxXg9606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:F4BF1E2DBEBFBDF2|rigid:tIADlgPbpyv+4HpWt/GljsgAVdU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q9NZS9	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-2130199|uniprotkb:A8K4Z9|uniprotkb:D3DUG8|uniprotkb:B4DUT0|ensembl:ENSP00000261658|ensembl:ENSP00000478190	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:bfar_human(display_long)|uniprotkb:BFAR(gene name)|psi-mi:BFAR(display_short)|uniprotkb:BAR(gene name synonym)|uniprotkb:RNF47(gene name synonym)|uniprotkb:RING finger protein 47(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341972|imex:IM-11696-500	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_057645.1|refseq:XP_005255407.1|ensembl:ENSG00000103429(gene)|ensembl:ENSG00000275618(gene)|ensembl:ENST00000261658(transcript)|ensembl:ENST00000619034(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017907	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:XDPFsRmdbch1NXffLOcE0lVrtRo9606	intact-crc:A80AA37669BF3A80|rigid:akQk/8F0zYi5hkffY6Pe6Sp/JGc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q8WVD3	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-749039|uniprotkb:Q9H8K2|uniprotkb:Q9UF87|uniprotkb:Q9UKI6|uniprotkb:B2RE17|ensembl:ENSP00000261593	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:rn138_human(display_long)|uniprotkb:RING finger protein 138(gene name synonym)|uniprotkb:Nemo-like kinase-associated RING finger protein(gene name synonym)|uniprotkb:RNF138(gene name)|psi-mi:RNF138(display_short)|uniprotkb:NARF(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF138(gene name synonym)|uniprotkb:HSD-4(orf name)|uniprotkb:HSD4(orf name)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341975|imex:IM-11696-501	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_057355.2|refseq:NP_937761.1|refseq:NP_001178253.2|refseq:XP_005258343.1|ensembl:ENSG00000134758(gene)|ensembl:ENST00000261593(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034734|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:HhGscRenFoqXTiZxHR62E4wcIo09606	intact-crc:AA82164A363B4787|rigid:t0ckrAtjGHh1acBCcbbcAfpXZQ8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q6PCD5	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-2129159|uniprotkb:Q9H9Q3|uniprotkb:Q9NVT4|uniprotkb:Q5XKR3|uniprotkb:A8K585|uniprotkb:B2RE35|uniprotkb:D3DUJ8|ensembl:ENSP00000354361|ensembl:ENSP00000460049	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:rfwd3_human(display_long)|uniprotkb:RFWD3(gene name)|psi-mi:RFWD3(display_short)|uniprotkb:RING finger and WD repeat domain-containing protein 3(gene name synonym)|uniprotkb:RNF201(gene name synonym)|uniprotkb:RING finger protein 201(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341987|imex:IM-11696-505	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:XP_011521493.1|refseq:NP_060594.3|refseq:XP_016878880.1|refseq:XP_005256078.1|refseq:XP_005256079.1|dip:DIP-52688N|ensembl:ENSG00000168411(gene)|ensembl:ENST00000361070(transcript)|ensembl:ENST00000571750(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031297"(replication fork processing)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037381|rcsb pdb:6CVZ	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:r7gkMbkS0GKPVn9riLPR34KFaKk9606	intact-crc:157D6BE40170330A|rigid:y221RCtU00PdvVzxrnEmcEdxvSI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q6ZNA4	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-2129175|uniprotkb:Q6ZMU2|uniprotkb:Q7L428|uniprotkb:Q7Z346|uniprotkb:Q8N1P9|uniprotkb:Q8WUA3|uniprotkb:Q9NSR1|uniprotkb:Q6P9A4|uniprotkb:C9JUS4|uniprotkb:H0YN55|ensembl:ENSP00000452732|intact:EBI-28970158	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:rn111_human(display_long)|uniprotkb:RNF111(gene name)|psi-mi:RNF111(display_short)|uniprotkb:RING finger protein 111(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Arkadia(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341981|imex:IM-11696-503	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_060080.6|ensembl:ENST00000348370|ensembl:ENSP00000288199|ensembl:ENSP00000452732|ensembl:ENST00000559209|ensembl:ENSP00000453872|ensembl:ENST00000561186|ensembl:ENSP00000453015|refseq:NP_001317260.1|refseq:XP_016877827.1|refseq:XP_006720642.1|refseq:NP_001257459.1|refseq:NP_001257457.1|refseq:NP_001257458.1|ensembl:ENSG00000157450(gene)|ensembl:ENST00000557998(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR029306|rcsb pdb:2KIZ|rcsb pdb:5LG0|rcsb pdb:5LG7|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-5696395|reactome:R-HSA-983168|go:"GO:0032184"(SUMO polymer binding)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:6SY5oMr5u4mnVi+zdRboVljMGa09606	intact-crc:B071C20451C15EED|rigid:jQRFmh8wD4OYZMItT4QLuZZ8KeA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q96EQ8	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341984|imex:IM-11696-504	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	intact-crc:0250C778292BCB96|rigid:KWuaYK+u3npp+4BhLkWJIDyw5mo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q96EP1	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-718923|uniprotkb:A6NEN5|uniprotkb:Q96SL3|uniprotkb:Q9NRT4|uniprotkb:Q9NT32|uniprotkb:Q9NVD5|uniprotkb:B4DZ77|uniprotkb:B4E2L6|ensembl:ENSP00000392395	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:chfr_human(display_long)|uniprotkb:Checkpoint with forkhead and RING finger domains protein(gene name synonym)|uniprotkb:RING finger protein 196(gene name synonym)|uniprotkb:CHFR(gene name)|psi-mi:CHFR(display_short)|uniprotkb:RNF196(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHFR(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341990|imex:IM-11696-506	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_001154816.1|refseq:NP_001154817.1|refseq:NP_001154818.1|refseq:NP_001154819.1|refseq:NP_060693.2|ensembl:ENSG00000072609(gene)|ensembl:ENST00000432561(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR019406|interpro:IPR040909|rcsb pdb:1LGP|rcsb pdb:1LGQ|rcsb pdb:2XOC|rcsb pdb:2XOY|rcsb pdb:2XOZ|rcsb pdb:2XP0|dip:DIP-40098N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid://FU72n6rmuPAu+Fjm377S4nEjw9606	intact-crc:696521731F3D7F45|rigid:fvoa37FeDzXmDKmqnDXisyq+TVo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q9Y508	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-723587|uniprotkb:Q6N0B0|uniprotkb:B2RDQ9|uniprotkb:B4DWY5|uniprotkb:E1P627|ensembl:ENSP00000244061	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:rn114_human(display_long)|uniprotkb:Zinc finger protein 313(gene name synonym)|uniprotkb:RNF114(gene name)|psi-mi:RNF114(display_short)|uniprotkb:ZNF313(gene name synonym)|uniprotkb:ZNF228(gene name synonym)|uniprotkb:Zinc finger protein 228(gene name synonym)|uniprotkb:RING finger protein 114(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF114(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341993|imex:IM-11696-507	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_061153.1|ensembl:ENSG00000124226(gene)|ensembl:ENST00000244061(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR034734|interpro:IPR042716|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:R1fX8xaGuIhy/M6cLzPeyfJBf649606	intact-crc:1A698F7F03EFA115|rigid:uvBuGBb4t6hZAjyfNjl8BDx8YN0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96GF1	uniprotkb:Q96B02	intact:EBI-2340249|uniprotkb:A8K5C1|uniprotkb:A9X3T8|uniprotkb:Q8N900|ensembl:ENSP00000320508|ensembl:ENSP00000427755	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:rn185_human(display_long)|uniprotkb:RNF185(gene name)|psi-mi:RNF185(display_short)|uniprotkb:RING finger protein 185(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF185(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342002|imex:IM-11696-510	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001129297.1|refseq:NP_689480.2|ensembl:ENSG00000138942(gene)|ensembl:ENST00000326132(transcript)|ensembl:ENST00000518626(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ivzbt31KPTKL/Rc1Wzs3h80XJac9606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:0C93081189123CC6|rigid:5ZLCS+ASaSrWFxEl75UI94Fsv6w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCM9	uniprotkb:Q96B02	intact:EBI-739510|uniprotkb:Q5STG4|uniprotkb:Q76BL3|uniprotkb:Q8IYT9|uniprotkb:Q96IB6|ensembl:ENSP00000365844|ensembl:ENSP00000373096|ensembl:ENSP00000379796|ensembl:ENSP00000391917|ensembl:ENSP00000397043|ensembl:ENSP00000398355|ensembl:ENSP00000409902|ensembl:ENSP00000411949|ensembl:ENSP00000447835|ensembl:ENSP00000448462|ensembl:ENSP00000448572|ensembl:ENSP00000449272|ensembl:ENSP00000449847|ensembl:ENSP00000450288|uniprotkb:Q5STG3	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:tri39_human(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341996|imex:IM-11696-508	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376656(transcript)|ensembl:ENST00000383602(transcript)|ensembl:ENST00000396547(transcript)|ensembl:ENST00000413715(transcript)|ensembl:ENST00000424575(transcript)|ensembl:ENST00000445206(transcript)|ensembl:ENST00000426469(transcript)|ensembl:ENST00000451715(transcript)|ensembl:ENST00000547030(transcript)|ensembl:ENST00000548002(transcript)|ensembl:ENST00000549841(transcript)|ensembl:ENST00000550282(transcript)|ensembl:ENST00000552337(transcript)|ensembl:ENST00000552520(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035033|interpro:IPR043136|mint:Q9HCM9|rcsb pdb:2DID|rcsb pdb:2DIF|rcsb pdb:2ECJ|reactome:R-HSA-983168|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_067076.2|refseq:NP_742013.1	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:xMCXGcMTqCjzLQzC53o81S4gqZA9606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:374DB737870EDEBE|rigid:aYSjGCi8lzIDCjTvBPe+GulAHzA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6UWE0	uniprotkb:Q96B02	intact:EBI-720984|uniprotkb:Q5VVV0|uniprotkb:Q8NB40|uniprotkb:Q96GT5|uniprotkb:Q96MX5|uniprotkb:Q96MZ7|ensembl:ENSP00000300417|ensembl:ENSP00000322937|ensembl:ENSP00000362419|ensembl:ENSP00000502167	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:lrsm1_human(display_long)|uniprotkb:Leucine-rich repeat and sterile alpha motif-containing protein 1(gene name synonym)|uniprotkb:Tsg101-associated ligase(gene name synonym)|uniprotkb:LRSAM1(gene name)|psi-mi:LRSAM1(display_short)|uniprotkb:TAL(gene name synonym)|uniprotkb:UNQ6496/PRO21356(orf name)|uniprotkb:RING-type E3 ubiquitin transferase LRSAM1(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2341999|imex:IM-11696-509	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005373.1|refseq:NP_001005374.1|refseq:NP_001177652.1|refseq:NP_612370.3|refseq:XP_016870772.1|ensembl:ENSG00000148356(gene)|ensembl:ENST00000300417(transcript)|ensembl:ENST00000323301(transcript)|ensembl:ENST00000373322(transcript)|ensembl:ENST00000675448(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0046755"(viral budding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032675|mint:Q6UWE0|reactome:R-HSA-983168	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:qkwPqOsfNjZBB2Xp6YAA9FbEZxM9606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:F97BDF23D573E977|rigid:s+wmZyqqGw+au8yaw4jTcLcmyiM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96P09	uniprotkb:Q96B02	intact:EBI-2341055|uniprotkb:Q96RW5|uniprotkb:Q6IPY1	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:birc8_human(display_long)|uniprotkb:BIRC8(gene name)|psi-mi:BIRC8(display_short)|uniprotkb:ILP2(gene name synonym)|uniprotkb:Inhibitor of apoptosis-like protein 2(gene name synonym)|uniprotkb:Testis-specific inhibitor of apoptosis(gene name synonym)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342005|imex:IM-11696-511	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR042579|refseq:NP_203127.3|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:1XB0|rcsb pdb:1XB1|interpro:IPR011029(DEATH-like)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dNa54zbu4SMSRJ8FXGBLuqGJ0qo9606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	intact-crc:E72B77C322F71A36|rigid:EVzjORWNiutcuh2ij6UzSSGENW0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q86UD3	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-2341065|uniprotkb:A8K264|uniprotkb:B9EJE7|ensembl:ENSP00000309141	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:marh3_human(display_long)|uniprotkb:MARCHF3(gene name)|psi-mi:MARCHF3(display_short)|uniprotkb:MARCH3(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 3(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein III(gene name synonym)|uniprotkb:RING finger protein 173(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF3(gene name synonym)|uniprotkb:RNF173(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342008|imex:IM-11696-512	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_848545.1|ensembl:ENSG00000173926(gene)|ensembl:ENST00000308660(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:uv/JcWUoL549NACFaOUs/oLdHuI9606	intact-crc:FA0682D87E67F15C|rigid:ELIEK+vRc9br5S4THdb4gY/DFaU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6UWE0	uniprotkb:Q8IX04	intact:EBI-720984|uniprotkb:Q5VVV0|uniprotkb:Q8NB40|uniprotkb:Q96GT5|uniprotkb:Q96MX5|uniprotkb:Q96MZ7|ensembl:ENSP00000300417|ensembl:ENSP00000322937|ensembl:ENSP00000362419|ensembl:ENSP00000502167	intact:EBI-2339926|uniprotkb:Q96FF5|uniprotkb:Q6P2F0|uniprotkb:Q9NUX7|uniprotkb:B2RB69|uniprotkb:F5H6L6|uniprotkb:B4DL43|uniprotkb:H7BYD6|ensembl:ENSP00000379500	psi-mi:lrsm1_human(display_long)|uniprotkb:Leucine-rich repeat and sterile alpha motif-containing protein 1(gene name synonym)|uniprotkb:Tsg101-associated ligase(gene name synonym)|uniprotkb:LRSAM1(gene name)|psi-mi:LRSAM1(display_short)|uniprotkb:TAL(gene name synonym)|uniprotkb:UNQ6496/PRO21356(orf name)|uniprotkb:RING-type E3 ubiquitin transferase LRSAM1(gene name synonym)	psi-mi:uevld_human(display_long)|uniprotkb:UEVLD(gene name)|psi-mi:UEVLD(display_short)|uniprotkb:UEV3(gene name synonym)|uniprotkb:EV and lactate/malate dehydrogenase domain-containing protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342017|imex:IM-11696-515	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005373.1|refseq:NP_001005374.1|refseq:NP_001177652.1|refseq:NP_612370.3|refseq:XP_016870772.1|ensembl:ENSG00000148356(gene)|ensembl:ENST00000300417(transcript)|ensembl:ENST00000323301(transcript)|ensembl:ENST00000373322(transcript)|ensembl:ENST00000675448(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0046755"(viral budding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032675|mint:Q6UWE0|reactome:R-HSA-983168	refseq:NP_001035787.1|refseq:NP_060784.3|refseq:NP_001284700.1|refseq:NP_001248312.1|refseq:NP_001248314.1|refseq:NP_001248311.1|refseq:NP_001248315.1|ensembl:ENSG00000151116(gene)|ensembl:ENST00000396197(transcript)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0015031"(protein transport)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR022383|interpro:IPR036291|rcsb pdb:2I6T|rcsb pdb:3DL2	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:qkwPqOsfNjZBB2Xp6YAA9FbEZxM9606	rogid:ZoLQ2ktG7JpK/ocZ+iC65EG5vrc9606	intact-crc:0B96013371A61254|rigid:tBW14xEOrH48BKG+xpQMs19tO4E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B02	uniprotkb:Q8N9I9	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	intact:EBI-2340258|uniprotkb:Q8NDS8|uniprotkb:Q8NAU6|uniprotkb:Q53ZZ2|ensembl:ENSP00000338050|ensembl:ENSP00000447873|ensembl:ENSP00000449294	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:dtx3_human(display_long)|uniprotkb:DTX3(gene name)|psi-mi:DTX3(display_short)|uniprotkb:RNF154(gene name synonym)|uniprotkb:RING finger protein 154(gene name synonym)|uniprotkb:Protein deltex-3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342011|imex:IM-11696-513	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	refseq:NP_001273174.1|refseq:NP_001273175.1|refseq:XP_011536324.1|refseq:NP_848597.1|refseq:XP_005268754.1|refseq:XP_005268755.1|refseq:XP_005268757.1|refseq:XP_005268760.1|ensembl:ENSG00000178498(gene)|ensembl:ENST00000337737(transcript)|ensembl:ENST00000548198(transcript)|ensembl:ENST00000548804(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rogid:Ma7JBhgMdFofCeWESbf8h1iLAHY9606	intact-crc:AD5F8B5391D245A4|rigid:2IwkaoQnaRtUyAAlZyUT9vpHMdk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IX04	uniprotkb:Q9Y4K3	intact:EBI-2339926|uniprotkb:Q96FF5|uniprotkb:Q6P2F0|uniprotkb:Q9NUX7|uniprotkb:B2RB69|uniprotkb:F5H6L6|uniprotkb:B4DL43|uniprotkb:H7BYD6|ensembl:ENSP00000379500	intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|ensembl:ENSP00000337853|ensembl:ENSP00000433623|uniprotkb:D3DR16	psi-mi:uevld_human(display_long)|uniprotkb:UEVLD(gene name)|psi-mi:UEVLD(display_short)|uniprotkb:UEV3(gene name synonym)|uniprotkb:EV and lactate/malate dehydrogenase domain-containing protein(gene name synonym)	psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342014|imex:IM-11696-514	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035787.1|refseq:NP_060784.3|refseq:NP_001284700.1|refseq:NP_001248312.1|refseq:NP_001248314.1|refseq:NP_001248311.1|refseq:NP_001248315.1|ensembl:ENSG00000151116(gene)|ensembl:ENST00000396197(transcript)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0015031"(protein transport)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR022383|interpro:IPR036291|rcsb pdb:2I6T|rcsb pdb:3DL2	refseq:NP_004611.1|refseq:NP_665802.1|ensembl:ENSG00000175104(gene)|ensembl:ENST00000348124(transcript)|ensembl:ENST00000526995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|go:"GO:0070534"(protein K63-linked ubiquitination)|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|go:"GO:0070555"(response to interleukin-1)|rcsb pdb:7L3L|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|go:"GO:0071222"(cellular response to lipopolysaccharide)|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-975871|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|dip:DIP-27515N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ZoLQ2ktG7JpK/ocZ+iC65EG5vrc9606	rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606	intact-crc:DF38DDCCF18C89F7|rigid:P6HBqMd7g4GUyuY6KaUY84f46W8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IX04	uniprotkb:Q8N9I9	intact:EBI-2339926|uniprotkb:Q96FF5|uniprotkb:Q6P2F0|uniprotkb:Q9NUX7|uniprotkb:B2RB69|uniprotkb:F5H6L6|uniprotkb:B4DL43|uniprotkb:H7BYD6|ensembl:ENSP00000379500	intact:EBI-2340258|uniprotkb:Q8NDS8|uniprotkb:Q8NAU6|uniprotkb:Q53ZZ2|ensembl:ENSP00000338050|ensembl:ENSP00000447873|ensembl:ENSP00000449294	psi-mi:uevld_human(display_long)|uniprotkb:UEVLD(gene name)|psi-mi:UEVLD(display_short)|uniprotkb:UEV3(gene name synonym)|uniprotkb:EV and lactate/malate dehydrogenase domain-containing protein(gene name synonym)	psi-mi:dtx3_human(display_long)|uniprotkb:DTX3(gene name)|psi-mi:DTX3(display_short)|uniprotkb:RNF154(gene name synonym)|uniprotkb:RING finger protein 154(gene name synonym)|uniprotkb:Protein deltex-3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342020|imex:IM-11696-516	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035787.1|refseq:NP_060784.3|refseq:NP_001284700.1|refseq:NP_001248312.1|refseq:NP_001248314.1|refseq:NP_001248311.1|refseq:NP_001248315.1|ensembl:ENSG00000151116(gene)|ensembl:ENST00000396197(transcript)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0015031"(protein transport)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR022383|interpro:IPR036291|rcsb pdb:2I6T|rcsb pdb:3DL2	refseq:NP_001273174.1|refseq:NP_001273175.1|refseq:XP_011536324.1|refseq:NP_848597.1|refseq:XP_005268754.1|refseq:XP_005268755.1|refseq:XP_005268757.1|refseq:XP_005268760.1|ensembl:ENSG00000178498(gene)|ensembl:ENST00000337737(transcript)|ensembl:ENST00000548198(transcript)|ensembl:ENST00000548804(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ZoLQ2ktG7JpK/ocZ+iC65EG5vrc9606	rogid:Ma7JBhgMdFofCeWESbf8h1iLAHY9606	intact-crc:F5348576971F8192|rigid:zwB2S66OLDjtkLV2IUivnjMxCu0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:Q9C0C9	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342023|imex:IM-11696-517	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	intact-crc:C44817D356A2D30C|rigid:I2xbxxdJc1zBTqCxq7pD+OQIfD8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WV44	uniprotkb:Q9H8T0	intact:EBI-725997|uniprotkb:Q5BKT0|uniprotkb:Q7L484|uniprotkb:Q96Q10|intact:EBI-1551110|uniprotkb:Q9BSL8|uniprotkb:B3KNJ6|uniprotkb:D3DWR9|ensembl:ENSP00000320869	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	psi-mi:tri41_human(display_long)|uniprotkb:TRIM41(gene name)|psi-mi:TRIM41(display_short)|uniprotkb:RINCK(gene name synonym)|uniprotkb:Tripartite motif-containing protein 41(gene name synonym)|uniprotkb:RING finger-interacting protein with C kinase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM41(gene name synonym)	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342032|imex:IM-11696-520	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_291027.3|refseq:NP_963921.1|ensembl:ENSG00000146063(gene)|ensembl:ENST00000315073(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042828|interpro:IPR043136|mint:Q8WV44|rcsb pdb:2EGM|reactome:R-HSA-983168	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:BVqf0OHXPGsYe8F66mHzvD4XQ549606	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	intact-crc:50C4808660FC319B|rigid:T0UkmRkl5Llha2dzxgrLUkrsCN0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36406	uniprotkb:Q9H8T0	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342026|imex:IM-11696-518	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	intact-crc:E9625F9C1F7BED26|rigid:rrr4SBgD5QXp08dRwjAKlsBMhJc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H8T0	uniprotkb:Q9NX47	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	intact:EBI-2341610|ensembl:ENSP00000351813	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:marh5_human(display_long)|uniprotkb:MARCH5(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 5(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein V(gene name synonym)|uniprotkb:Mitochondrial ubiquitin ligase(gene name synonym)|uniprotkb:RING finger protein 153(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF5(gene name synonym)|uniprotkb:MARCHF5(gene name)|psi-mi:MARCHF5(display_short)|uniprotkb:RNF153(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342029|imex:IM-11696-519	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)	refseq:NP_060294.1|ensembl:ENSG00000198060(gene)|ensembl:ENST00000358935(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051020"(GTPase binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090344"(negative regulation of cell aging)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NX47	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	rogid:/w+L/oINlKM5ZSm1OkI+R+8PxXg9606	intact-crc:EEC91B032E2C0B9C|rigid:FzATz7BaA270Z4og4Cj7ixYlgwI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H832	uniprotkb:Q13702	intact:EBI-720977|uniprotkb:A6N8M6|uniprotkb:Q7L354|uniprotkb:Q8TCM4|uniprotkb:Q9H893|uniprotkb:A6NC60|ensembl:ENSP00000354201	intact:EBI-2342036|uniprotkb:Q9BTD9|uniprotkb:Q8TDF3|ensembl:ENSP00000298854	psi-mi:ube2z_human(display_long)|uniprotkb:Ubiquitin-protein ligase Z(gene name synonym)|uniprotkb:Ubiquitin carrier protein Z(gene name synonym)|uniprotkb:Uba6-specific E2 conjugating enzyme 1(gene name synonym)|uniprotkb:UBE2Z(gene name)|psi-mi:UBE2Z(display_short)|uniprotkb:HOYS7(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme Z(gene name synonym)	psi-mi:rapsn_human(display_long)|uniprotkb:RAPSN(gene name)|psi-mi:RAPSN(display_short)|uniprotkb:RNF205(gene name synonym)|uniprotkb:Acetylcholine receptor-associated 43 kDa protein(gene name synonym)|uniprotkb:43 kDa postsynaptic protein(gene name synonym)|uniprotkb:RING finger protein 205(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342035|imex:IM-11696-327	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075567.2|ensembl:ENSG00000159202(gene)|ensembl:ENST00000360943(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:5A4P|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_005046.2|refseq:NP_116034.2|ensembl:ENSG00000165917(gene)|ensembl:ENST00000298854(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:1900075"(positive regulation of neuromuscular synaptic transmission)|go:"GO:1901626"(regulation of postsynaptic membrane organization)|go:"GO:1903540"(establishment of protein localization to postsynaptic membrane)|interpro:IPR001237(43 kDa postsynaptic protein)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018293|interpro:IPR019568|interpro:IPR019734|interpro:IPR041617	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ha+cN8Y8XYZFrRnAQC9BRiMaUL89606	rogid:vqJ8shUwaTB6ONfWL8/qTWDqusI9606	intact-crc:4278C11A5D19E65E|rigid:sLtNyq3IV8Ng0PUgIkP3EnZNzCw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H832	uniprotkb:P14373	intact:EBI-720977|uniprotkb:A6N8M6|uniprotkb:Q7L354|uniprotkb:Q8TCM4|uniprotkb:Q9H893|uniprotkb:A6NC60|ensembl:ENSP00000354201	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:ube2z_human(display_long)|uniprotkb:Ubiquitin-protein ligase Z(gene name synonym)|uniprotkb:Ubiquitin carrier protein Z(gene name synonym)|uniprotkb:Uba6-specific E2 conjugating enzyme 1(gene name synonym)|uniprotkb:UBE2Z(gene name)|psi-mi:UBE2Z(display_short)|uniprotkb:HOYS7(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme Z(gene name synonym)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342044|imex:IM-11696-328	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075567.2|ensembl:ENSG00000159202(gene)|ensembl:ENST00000360943(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:5A4P|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ha+cN8Y8XYZFrRnAQC9BRiMaUL89606	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:AA8167040D89FA7E|rigid:izlhqlslEkrtp294cDbEXUDfQBY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99942	uniprotkb:Q9H832	intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3	intact:EBI-720977|uniprotkb:A6N8M6|uniprotkb:Q7L354|uniprotkb:Q8TCM4|uniprotkb:Q9H893|uniprotkb:A6NC60|ensembl:ENSP00000354201	psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym)	psi-mi:ube2z_human(display_long)|uniprotkb:Ubiquitin-protein ligase Z(gene name synonym)|uniprotkb:Ubiquitin carrier protein Z(gene name synonym)|uniprotkb:Uba6-specific E2 conjugating enzyme 1(gene name synonym)|uniprotkb:UBE2Z(gene name)|psi-mi:UBE2Z(display_short)|uniprotkb:HOYS7(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme Z(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342047|imex:IM-11696-329	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N	refseq:NP_075567.2|ensembl:ENSG00000159202(gene)|ensembl:ENST00000360943(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:5A4P|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606	rogid:ha+cN8Y8XYZFrRnAQC9BRiMaUL89606	intact-crc:2C80F9CC10906E5F|rigid:w7gwNiekGkEtogPg+9bbLwvxrJU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H832	uniprotkb:Q86Y13	intact:EBI-720977|uniprotkb:A6N8M6|uniprotkb:Q7L354|uniprotkb:Q8TCM4|uniprotkb:Q9H893|uniprotkb:A6NC60|ensembl:ENSP00000354201	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:ube2z_human(display_long)|uniprotkb:Ubiquitin-protein ligase Z(gene name synonym)|uniprotkb:Ubiquitin carrier protein Z(gene name synonym)|uniprotkb:Uba6-specific E2 conjugating enzyme 1(gene name synonym)|uniprotkb:UBE2Z(gene name)|psi-mi:UBE2Z(display_short)|uniprotkb:HOYS7(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme Z(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342050|imex:IM-11696-330	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075567.2|ensembl:ENSG00000159202(gene)|ensembl:ENST00000360943(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:5A4P|reactome:R-HSA-8866652|reactome:R-HSA-983168	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ha+cN8Y8XYZFrRnAQC9BRiMaUL89606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:6659697FFA3EA9D5|rigid:Y/JHbrzRKXtWTormlaYQQV8A3oM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H832	uniprotkb:Q7Z4K8	intact:EBI-720977|uniprotkb:A6N8M6|uniprotkb:Q7L354|uniprotkb:Q8TCM4|uniprotkb:Q9H893|uniprotkb:A6NC60|ensembl:ENSP00000354201	intact:EBI-723344|uniprotkb:Q6NT17|uniprotkb:Q6NT41|uniprotkb:Q6ZRL7|uniprotkb:Q9H5P2|ensembl:ENSP00000334657|uniprotkb:A0AVI6|uniprotkb:Q5VT60|uniprotkb:Q5VT62|uniprotkb:B1AVQ4	psi-mi:ube2z_human(display_long)|uniprotkb:Ubiquitin-protein ligase Z(gene name synonym)|uniprotkb:Ubiquitin carrier protein Z(gene name synonym)|uniprotkb:Uba6-specific E2 conjugating enzyme 1(gene name synonym)|uniprotkb:UBE2Z(gene name)|psi-mi:UBE2Z(display_short)|uniprotkb:HOYS7(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme Z(gene name synonym)	psi-mi:tri46_human(display_long)|uniprotkb:Tripartite, fibronectin type-III and C-terminal SPRY motif protein(gene name synonym)|uniprotkb:Gene Y protein(gene name synonym)|uniprotkb:TRIM46(gene name)|psi-mi:TRIM46(display_short)|uniprotkb:TRIFIC(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342056|imex:IM-11696-522	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075567.2|ensembl:ENSG00000159202(gene)|ensembl:ENST00000360943(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:5A4P|reactome:R-HSA-8866652|reactome:R-HSA-983168	refseq:NP_079334.3|ensembl:ENSG00000163462(gene)|ensembl:ENST00000334634(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001764"(neuron migration)|interpro:IPR027370|interpro:IPR035731|interpro:IPR036116|interpro:IPR040859|interpro:IPR043136|reactome:R-HSA-877300|go:"GO:0005856"(cytoskeleton)|go:"GO:0007409"(axonogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0043194"(axon initial segment)|go:"GO:0044304"(main axon)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0099612"(protein localization to axon)|go:"GO:1901953"(positive regulation of anterograde dense core granule transport)|go:"GO:1903827"|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990769"(proximal neuron projection)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|refseq:NP_001243528.1|refseq:NP_001243529.1|refseq:NP_001243530.1|refseq:NP_001269307.1|refseq:NP_001269308.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ha+cN8Y8XYZFrRnAQC9BRiMaUL89606	rogid:Te5aeDC5aMKYNhajjekIRJCtzBQ9606	intact-crc:DE8E2CC9BFE9C26D|rigid:1YWqvQbBY4m0r9BDqQnQy356uZA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96A37	uniprotkb:Q9H832	intact:EBI-2130320|uniprotkb:B3KQ03|uniprotkb:Q96DM0|uniprotkb:D3DX75|uniprotkb:H3BTU8|ensembl:ENSP00000326095	intact:EBI-720977|uniprotkb:A6N8M6|uniprotkb:Q7L354|uniprotkb:Q8TCM4|uniprotkb:Q9H893|uniprotkb:A6NC60|ensembl:ENSP00000354201	psi-mi:rn166_human(display_long)|uniprotkb:RNF166(gene name)|psi-mi:RNF166(display_short)|uniprotkb:RING finger protein 166(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF166(gene name synonym)	psi-mi:ube2z_human(display_long)|uniprotkb:Ubiquitin-protein ligase Z(gene name synonym)|uniprotkb:Ubiquitin carrier protein Z(gene name synonym)|uniprotkb:Uba6-specific E2 conjugating enzyme 1(gene name synonym)|uniprotkb:UBE2Z(gene name)|psi-mi:UBE2Z(display_short)|uniprotkb:HOYS7(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme Z(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342059|imex:IM-11696-523	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001165286.1|refseq:NP_001165287.1|refseq:NP_849163.1|refseq:XP_016878402.1|ensembl:ENSG00000158717(gene)|ensembl:ENST00000312838(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734	refseq:NP_075567.2|ensembl:ENSG00000159202(gene)|ensembl:ENST00000360943(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:5A4P|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:QV195sbjVofHePvnO8nsleiWSkg9606	rogid:ha+cN8Y8XYZFrRnAQC9BRiMaUL89606	intact-crc:FD6FB178A522D995|rigid:XNu5+qoVOxwj9wJjyz87fI2jhig	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BWF2	uniprotkb:Q9H832	intact:EBI-1756205|uniprotkb:O00467|uniprotkb:B5BU84|uniprotkb:B5BUL3|intact:EBI-28986477|ensembl:ENSP00000328203	intact:EBI-720977|uniprotkb:A6N8M6|uniprotkb:Q7L354|uniprotkb:Q8TCM4|uniprotkb:Q9H893|uniprotkb:A6NC60|ensembl:ENSP00000354201	psi-mi:traip_human(display_long)|uniprotkb:TRAIP(gene name)|psi-mi:TRAIP(display_short)|uniprotkb:RNF206(gene name synonym)|uniprotkb:TRIP(gene name synonym)|uniprotkb:RING finger protein 206(gene name synonym)|uniprotkb:TRAF-interacting protein(gene name synonym)	psi-mi:ube2z_human(display_long)|uniprotkb:Ubiquitin-protein ligase Z(gene name synonym)|uniprotkb:Ubiquitin carrier protein Z(gene name synonym)|uniprotkb:Uba6-specific E2 conjugating enzyme 1(gene name synonym)|uniprotkb:UBE2Z(gene name)|psi-mi:UBE2Z(display_short)|uniprotkb:HOYS7(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme Z(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342053|imex:IM-11696-521	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005870.2|ensembl:ENSP00000328203|ensembl:ENSG00000183763(gene)|ensembl:ENST00000331456(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007165"(signal transduction)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090734"(site of DNA damage)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:4ZTD|reactome:R-HSA-983168	refseq:NP_075567.2|ensembl:ENSG00000159202(gene)|ensembl:ENST00000360943(transcript)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:5A4P|reactome:R-HSA-8866652|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:af6osyzc1Cw/atmwUPTR1f5usBE9606	rogid:ha+cN8Y8XYZFrRnAQC9BRiMaUL89606	intact-crc:DB37560FE2DB6E4E|rigid:Z/FSOm5tGly4xg0kttTH3qGBeDM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6ZNA4	uniprotkb:Q8WVN8	intact:EBI-2129175|uniprotkb:Q6ZMU2|uniprotkb:Q7L428|uniprotkb:Q7Z346|uniprotkb:Q8N1P9|uniprotkb:Q8WUA3|uniprotkb:Q9NSR1|uniprotkb:Q6P9A4|uniprotkb:C9JUS4|uniprotkb:H0YN55|ensembl:ENSP00000452732|intact:EBI-28970158	intact:EBI-2130157|uniprotkb:Q8N4G6|uniprotkb:Q96J08|uniprotkb:B7Z3Q2|uniprotkb:H3BRG2|ensembl:ENSP00000267938	psi-mi:rn111_human(display_long)|uniprotkb:RNF111(gene name)|psi-mi:RNF111(display_short)|uniprotkb:RING finger protein 111(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Arkadia(gene name synonym)	psi-mi:ub2q2_human(display_long)|uniprotkb:UBE2Q2(gene name)|psi-mi:UBE2Q2(display_short)|uniprotkb:Ubiquitin-protein ligase Q2(gene name synonym)|uniprotkb:Ubiquitin carrier protein Q2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme Q2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342062|imex:IM-11696-524	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060080.6|ensembl:ENST00000348370|ensembl:ENSP00000288199|ensembl:ENSP00000452732|ensembl:ENST00000559209|ensembl:ENSP00000453872|ensembl:ENST00000561186|ensembl:ENSP00000453015|refseq:NP_001317260.1|refseq:XP_016877827.1|refseq:XP_006720642.1|refseq:NP_001257459.1|refseq:NP_001257457.1|refseq:NP_001257458.1|ensembl:ENSG00000157450(gene)|ensembl:ENST00000557998(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR029306|rcsb pdb:2KIZ|rcsb pdb:5LG0|rcsb pdb:5LG7|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-5696395|reactome:R-HSA-983168|go:"GO:0032184"(SUMO polymer binding)	refseq:NP_001271311.1|refseq:NP_001138807.1|refseq:NP_775740.1|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:1ZUO|reactome:R-HSA-8866652|reactome:R-HSA-983168|go:"GO:0005829"(cytosol)|ensembl:ENSG00000140367(gene)|ensembl:ENST00000267938(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:6SY5oMr5u4mnVi+zdRboVljMGa09606	rogid:3rt+W5KJJW5Hmkl+y5+0VaMpDLU9606	intact-crc:FA09D745BDA6EE56|rigid:ziUcWrlp90ZOVxTNSrXsoeIRvcc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P98170	uniprotkb:Q8WVN8	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	intact:EBI-2130157|uniprotkb:Q8N4G6|uniprotkb:Q96J08|uniprotkb:B7Z3Q2|uniprotkb:H3BRG2|ensembl:ENSP00000267938	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:ub2q2_human(display_long)|uniprotkb:UBE2Q2(gene name)|psi-mi:UBE2Q2(display_short)|uniprotkb:Ubiquitin-protein ligase Q2(gene name synonym)|uniprotkb:Ubiquitin carrier protein Q2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme Q2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342065|imex:IM-11696-525	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	refseq:NP_001271311.1|refseq:NP_001138807.1|refseq:NP_775740.1|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:1ZUO|reactome:R-HSA-8866652|reactome:R-HSA-983168|go:"GO:0005829"(cytosol)|ensembl:ENSG00000140367(gene)|ensembl:ENST00000267938(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	rogid:3rt+W5KJJW5Hmkl+y5+0VaMpDLU9606	intact-crc:B70AC75C0CAE41C1|rigid:RjiPyaatyOOf9o1+F2u2Ujv0tfI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14258	uniprotkb:Q8WVN8	intact:EBI-2341129|intact:EBI-28973868|ensembl:ENSP00000323889|ensembl:ENSP00000445961	intact:EBI-2130157|uniprotkb:Q8N4G6|uniprotkb:Q96J08|uniprotkb:B7Z3Q2|uniprotkb:H3BRG2|ensembl:ENSP00000267938	psi-mi:tri25_human(display_long)|uniprotkb:TRIM25(gene name)|psi-mi:TRIM25(display_short)|uniprotkb:EFP(gene name synonym)|uniprotkb:RNF147(gene name synonym)|uniprotkb:ZNF147(gene name synonym)|uniprotkb:Zinc finger protein 147(gene name synonym)|uniprotkb:Estrogen-responsive finger protein(gene name synonym)|uniprotkb:RING finger protein 147(gene name synonym)|uniprotkb:Ubiquitin/ISG15-conjugating enzyme TRIM25(gene name synonym)|uniprotkb:Tripartite motif-containing protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM25(gene name synonym)	psi-mi:ub2q2_human(display_long)|uniprotkb:UBE2Q2(gene name)|psi-mi:UBE2Q2(display_short)|uniprotkb:Ubiquitin-protein ligase Q2(gene name synonym)|uniprotkb:Ubiquitin carrier protein Q2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme Q2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342068|imex:IM-11696-526	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000323889|ensembl:ENSP00000445961|refseq:NP_005073.2|ensembl:ENSG00000121060(gene)|ensembl:ENST00000316881(transcript)|ensembl:ENST00000537230(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016604"(nuclear body)|go:"GO:0016874"(ligase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033280"(response to vitamin D)|go:"GO:0039552"(RIG-I binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043627"(response to estrogen)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|go:"GO:1902187"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042753|interpro:IPR043136|mint:Q14258|rcsb pdb:4CFG|rcsb pdb:4LTB|rcsb pdb:5EYA|rcsb pdb:5FER|rcsb pdb:5NT1|rcsb pdb:5NT2|rcsb pdb:6FLM|rcsb pdb:6FLN|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-5689896|reactome:R-HSA-877300|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440	refseq:NP_001271311.1|refseq:NP_001138807.1|refseq:NP_775740.1|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:1ZUO|reactome:R-HSA-8866652|reactome:R-HSA-983168|go:"GO:0005829"(cytosol)|ensembl:ENSG00000140367(gene)|ensembl:ENST00000267938(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:NhFfC0IxHvxPIt2YnKCPsPKuiQA9606	rogid:3rt+W5KJJW5Hmkl+y5+0VaMpDLU9606	intact-crc:1A2759B0421DBA86|rigid:0qZAKgy2AULWsDTgvK2hZzGgEvI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WVN8	uniprotkb:Q8N5U6	intact:EBI-2130157|uniprotkb:Q8N4G6|uniprotkb:Q96J08|uniprotkb:B7Z3Q2|uniprotkb:H3BRG2|ensembl:ENSP00000267938	intact:EBI-714023|uniprotkb:Q92550|uniprotkb:Q9NPP8|uniprotkb:Q9ULW4|ensembl:ENSP00000322242	psi-mi:ub2q2_human(display_long)|uniprotkb:UBE2Q2(gene name)|psi-mi:UBE2Q2(display_short)|uniprotkb:Ubiquitin-protein ligase Q2(gene name synonym)|uniprotkb:Ubiquitin carrier protein Q2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme Q2(gene name synonym)	psi-mi:rnf10_human(display_long)|uniprotkb:RNF10(gene name)|psi-mi:RNF10(display_short)|uniprotkb:KIAA0262(gene name synonym)|uniprotkb:RIE2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342071|imex:IM-11696-527	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271311.1|refseq:NP_001138807.1|refseq:NP_775740.1|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:1ZUO|reactome:R-HSA-8866652|reactome:R-HSA-983168|go:"GO:0005829"(cytosol)|ensembl:ENSG00000140367(gene)|ensembl:ENST00000267938(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)	refseq:NP_055683.3|refseq:NP_001317403.1|ensembl:ENSG00000022840(gene)|ensembl:ENST00000325954(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039739|mint:Q8N5U6	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:3rt+W5KJJW5Hmkl+y5+0VaMpDLU9606	rogid:Bca0Ae456x1eCsdlduoCbn7coUQ9606	intact-crc:E6CD30DC31B5F629|rigid:2vr+O5NnEwSc4zmhus8RCjg0de0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WVN8	uniprotkb:O60291	intact:EBI-2130157|uniprotkb:Q8N4G6|uniprotkb:Q96J08|uniprotkb:B7Z3Q2|uniprotkb:H3BRG2|ensembl:ENSP00000267938	intact:EBI-2129851|uniprotkb:A4URL3|uniprotkb:A4URL4|uniprotkb:Q86W76|intact:EBI-28986785|ensembl:ENSP00000382487	psi-mi:ub2q2_human(display_long)|uniprotkb:UBE2Q2(gene name)|psi-mi:UBE2Q2(display_short)|uniprotkb:Ubiquitin-protein ligase Q2(gene name synonym)|uniprotkb:Ubiquitin carrier protein Q2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme Q2(gene name synonym)	psi-mi:mgrn1_human(display_long)|uniprotkb:MGRN1(gene name)|psi-mi:MGRN1(display_short)|uniprotkb:KIAA0544(gene name synonym)|uniprotkb:RNF156(gene name synonym)|uniprotkb:Mahogunin RING finger protein 1(gene name synonym)|uniprotkb:RING finger protein 156(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MGRN1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342074|imex:IM-11696-528	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271311.1|refseq:NP_001138807.1|refseq:NP_775740.1|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:1ZUO|reactome:R-HSA-8866652|reactome:R-HSA-983168|go:"GO:0005829"(cytosol)|ensembl:ENSG00000140367(gene)|ensembl:ENST00000267938(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)	refseq:NP_001135761.2|refseq:NP_001135762.1|refseq:NP_001135763.2|refseq:NP_056061.1|ensembl:ENST00000262370|ensembl:ENSP00000262370|ensembl:ENSP00000382487|ensembl:ENST00000415496|ensembl:ENSP00000393311|ensembl:ENST00000586183|ensembl:ENSP00000465860|ensembl:ENST00000588994|ensembl:ENSP00000468819|refseq:XP_005255277.1|refseq:XP_005255278.1|ensembl:ENSG00000102858(gene)|ensembl:ENST00000399577(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:3rt+W5KJJW5Hmkl+y5+0VaMpDLU9606	rogid:UuLoCnlkpTBs/rmGgpQvgiMNuNE9606	intact-crc:A14B34A09DE15986|rigid:Qjwp3qZvZWexpgOyIg2LxUPi07Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VVX9	uniprotkb:Q86Y13	intact:EBI-2130181|uniprotkb:Q8N1D4|intact:EBI-28974117|ensembl:ENSP00000481174	intact:EBI-948630|ensembl:ENSP00000355028|ensembl:ENSP00000419981|uniprotkb:O75162|uniprotkb:Q6P3R9|uniprotkb:Q6PH82|uniprotkb:Q86Y14|uniprotkb:Q86Y15|uniprotkb:Q86Y16|uniprotkb:Q8IWI0|uniprotkb:Q96RS9|uniprotkb:B3KN01	psi-mi:ube2u_human(display_long)|uniprotkb:UBE2U(gene name)|psi-mi:UBE2U(display_short)|uniprotkb:Ubiquitin-protein ligase U(gene name synonym)|uniprotkb:Ubiquitin carrier protein U(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme U(gene name synonym)	psi-mi:dzip3_human(display_long)|uniprotkb:DAZ-interacting protein 3(gene name synonym)|uniprotkb:RNA-binding ubiquitin ligase of 138 kDa(gene name synonym)|uniprotkb:DZIP3(gene name)|psi-mi:DZIP3(display_short)|uniprotkb:KIAA0675(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DZIP3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342083|imex:IM-11696-531	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000371076|ensembl:ENSP00000360116|ensembl:ENSP00000481174|refseq:NP_689702.1|ensembl:ENSG00000177414(gene)|ensembl:ENST00000611228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033503"(HULC complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YRV|reactome:R-HSA-983168	ensembl:ENSG00000198919(gene)|ensembl:ENST00000361582(transcript)|ensembl:ENST00000463306(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR033103|interpro:IPR041249|interpro:IPR043866|reactome:R-HSA-983168|refseq:NP_055463.1|refseq:XP_005247973.1|refseq:XP_005247974.1|refseq:XP_005247975.1|refseq:XP_005247972.1|refseq:XP_005247971.1|refseq:XP_016863029.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:onw4DUslrZLhQZp8FtqY6s6Q/u09606	rogid:sXYt6+Ar+QmgZtB4OLLbZx3KZG49606	intact-crc:BA1A9C7B29347F5D|rigid:Gqks/9L77D0u7PFOAmHyIOWsiJ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969M7	uniprotkb:Q969K3	intact:EBI-1056876|uniprotkb:A8K1Z8|uniprotkb:B4DDT9|uniprotkb:B4DFI1|uniprotkb:B4DMK3|uniprotkb:B4DZU2|uniprotkb:B8ZZG2|uniprotkb:C9J212|uniprotkb:H9KVB9|ensembl:ENSP00000272930|ensembl:ENSP00000478474	intact:EBI-2340642|uniprotkb:Q8NG47|uniprotkb:Q9H6W8|uniprotkb:B7Z933|ensembl:ENSP00000355137	psi-mi:ube2f_human(display_long)|uniprotkb:UBE2F(gene name)|psi-mi:UBE2F(display_short)|uniprotkb:NCE2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 F(gene name synonym)|uniprotkb:NEDD8 protein ligase UBE2F(gene name synonym)|uniprotkb:NEDD8 carrier protein UBE2F(gene name synonym)|uniprotkb:NEDD8-conjugating enzyme 2(gene name synonym)|uniprotkb:RING-type E3 NEDD8 transferase UBE2F(gene name synonym)	psi-mi:rnf34_human(display_long)|uniprotkb:RNF34(gene name)|psi-mi:RNF34(display_short)|uniprotkb:RING finger protein 34(gene name synonym)|uniprotkb:RING finger protein RIFF(gene name synonym)|uniprotkb:FYVE-RING finger protein Momo(gene name synonym)|uniprotkb:Human RING finger homologous to inhibitor of apoptosis protein(gene name synonym)|uniprotkb:Caspases-8 and -10-associated RING finger protein 1(gene name synonym)|uniprotkb:Caspase regulator CARP1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF34(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342077|imex:IM-11696-529	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_542409.1|refseq:NP_001265234.1|refseq:NP_001265235.1|refseq:NP_001265236.1|refseq:NP_001265237.1|ensembl:ENSG00000184182(gene)|ensembl:ENST00000272930(transcript)|ensembl:ENST00000612130(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045116"(protein neddylation)|go:"GO:0061654"(NEDD8 conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2EDI|rcsb pdb:3FN1|rcsb pdb:4GBA|reactome:R-HSA-8951664|reactome:R-HSA-983168	refseq:NP_001243787.1|refseq:NP_079402.2|refseq:NP_919247.1|ensembl:ENSG00000170633(gene)|ensembl:ENST00000361234(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035872"(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901797"(negative regulation of signal transduction by p53 class mediator)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000374"(regulation of oxygen metabolic process)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR036361|mint:Q969K3|reactome:R-HSA-6804757|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Drl/c/EC3fscD9dEi4rEjAz9yTM9606	rogid:pvINlXbJ9UfZbyW4YqRO+HQsCnw9606	intact-crc:80C7C040EBA8D7B3|rigid:i30cCqrZnBrGHT3yKBAzRoSs/yw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:Q5VVX9	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-2130181|uniprotkb:Q8N1D4|intact:EBI-28974117|ensembl:ENSP00000481174	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:ube2u_human(display_long)|uniprotkb:UBE2U(gene name)|psi-mi:UBE2U(display_short)|uniprotkb:Ubiquitin-protein ligase U(gene name synonym)|uniprotkb:Ubiquitin carrier protein U(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme U(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342080|imex:IM-11696-530	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	ensembl:ENST00000371076|ensembl:ENSP00000360116|ensembl:ENSP00000481174|refseq:NP_689702.1|ensembl:ENSG00000177414(gene)|ensembl:ENST00000611228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033503"(HULC complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YRV|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:onw4DUslrZLhQZp8FtqY6s6Q/u09606	intact-crc:A82956137EA45F54|rigid:aiz3+1Ky1SXgdvwJLRhhvg2zp+I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VVX9	uniprotkb:Q8N5U6	intact:EBI-2130181|uniprotkb:Q8N1D4|intact:EBI-28974117|ensembl:ENSP00000481174	intact:EBI-714023|uniprotkb:Q92550|uniprotkb:Q9NPP8|uniprotkb:Q9ULW4|ensembl:ENSP00000322242	psi-mi:ube2u_human(display_long)|uniprotkb:UBE2U(gene name)|psi-mi:UBE2U(display_short)|uniprotkb:Ubiquitin-protein ligase U(gene name synonym)|uniprotkb:Ubiquitin carrier protein U(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme U(gene name synonym)	psi-mi:rnf10_human(display_long)|uniprotkb:RNF10(gene name)|psi-mi:RNF10(display_short)|uniprotkb:KIAA0262(gene name synonym)|uniprotkb:RIE2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342086|imex:IM-11696-532	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000371076|ensembl:ENSP00000360116|ensembl:ENSP00000481174|refseq:NP_689702.1|ensembl:ENSG00000177414(gene)|ensembl:ENST00000611228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033503"(HULC complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YRV|reactome:R-HSA-983168	refseq:NP_055683.3|refseq:NP_001317403.1|ensembl:ENSG00000022840(gene)|ensembl:ENST00000325954(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039739|mint:Q8N5U6	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:onw4DUslrZLhQZp8FtqY6s6Q/u09606	rogid:Bca0Ae456x1eCsdlduoCbn7coUQ9606	intact-crc:1BB8FAF5407F59AA|rigid:xLd1ikEKXomrn2VnHXnryR6Er+I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VVX9	uniprotkb:Q13049	intact:EBI-2130181|uniprotkb:Q8N1D4|intact:EBI-28974117|ensembl:ENSP00000481174	intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8	psi-mi:ube2u_human(display_long)|uniprotkb:UBE2U(gene name)|psi-mi:UBE2U(display_short)|uniprotkb:Ubiquitin-protein ligase U(gene name synonym)|uniprotkb:Ubiquitin carrier protein U(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme U(gene name synonym)	psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342089|imex:IM-11696-533	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000371076|ensembl:ENSP00000360116|ensembl:ENSP00000481174|refseq:NP_689702.1|ensembl:ENSG00000177414(gene)|ensembl:ENST00000611228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033503"(HULC complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YRV|reactome:R-HSA-983168	go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:onw4DUslrZLhQZp8FtqY6s6Q/u09606	rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606	intact-crc:4AF814F1CFEF2CB3|rigid:7DSDOGcJ57sAOq4u1rdwA3FZLpg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VVX9	uniprotkb:Q5JVY0	intact:EBI-2130181|uniprotkb:Q8N1D4|intact:EBI-28974117|ensembl:ENSP00000481174	intact:EBI-2342093|ensembl:ENSP00000412603	psi-mi:ube2u_human(display_long)|uniprotkb:UBE2U(gene name)|psi-mi:UBE2U(display_short)|uniprotkb:Ubiquitin-protein ligase U(gene name synonym)|uniprotkb:Ubiquitin carrier protein U(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme U(gene name synonym)	psi-mi:q5jvy0_human(display_long)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342092|imex:IM-11696-534	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000371076|ensembl:ENSP00000360116|ensembl:ENSP00000481174|refseq:NP_689702.1|ensembl:ENSG00000177414(gene)|ensembl:ENST00000611228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033503"(HULC complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YRV|reactome:R-HSA-983168	ensembl:ENSG00000119401(gene)|ensembl:ENST00000411410(transcript)|go:"GO:0008270"(zinc ion binding)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2016/12/06	rogid:onw4DUslrZLhQZp8FtqY6s6Q/u09606	rogid:Gka30ud928ljvOSHojSj3tbgqaY9606	intact-crc:9D79894CFC813119|rigid:US5USJNibW2GS7eT73AbKF3P9Rc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VVX9	uniprotkb:Q96EQ8	intact:EBI-2130181|uniprotkb:Q8N1D4|intact:EBI-28974117|ensembl:ENSP00000481174	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:ube2u_human(display_long)|uniprotkb:UBE2U(gene name)|psi-mi:UBE2U(display_short)|uniprotkb:Ubiquitin-protein ligase U(gene name synonym)|uniprotkb:Ubiquitin carrier protein U(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme U(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342099|imex:IM-11696-535	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000371076|ensembl:ENSP00000360116|ensembl:ENSP00000481174|refseq:NP_689702.1|ensembl:ENSG00000177414(gene)|ensembl:ENST00000611228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033503"(HULC complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YRV|reactome:R-HSA-983168	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:onw4DUslrZLhQZp8FtqY6s6Q/u09606	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	intact-crc:BC033DA57322E846|rigid:bRuGfkASZdV3N4GBtyTsQzyDoTk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VVX9	uniprotkb:Q7Z4K8	intact:EBI-2130181|uniprotkb:Q8N1D4|intact:EBI-28974117|ensembl:ENSP00000481174	intact:EBI-723344|uniprotkb:Q6NT17|uniprotkb:Q6NT41|uniprotkb:Q6ZRL7|uniprotkb:Q9H5P2|ensembl:ENSP00000334657|uniprotkb:A0AVI6|uniprotkb:Q5VT60|uniprotkb:Q5VT62|uniprotkb:B1AVQ4	psi-mi:ube2u_human(display_long)|uniprotkb:UBE2U(gene name)|psi-mi:UBE2U(display_short)|uniprotkb:Ubiquitin-protein ligase U(gene name synonym)|uniprotkb:Ubiquitin carrier protein U(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme U(gene name synonym)	psi-mi:tri46_human(display_long)|uniprotkb:Tripartite, fibronectin type-III and C-terminal SPRY motif protein(gene name synonym)|uniprotkb:Gene Y protein(gene name synonym)|uniprotkb:TRIM46(gene name)|psi-mi:TRIM46(display_short)|uniprotkb:TRIFIC(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342102|imex:IM-11696-536	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000371076|ensembl:ENSP00000360116|ensembl:ENSP00000481174|refseq:NP_689702.1|ensembl:ENSG00000177414(gene)|ensembl:ENST00000611228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033503"(HULC complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YRV|reactome:R-HSA-983168	refseq:NP_079334.3|ensembl:ENSG00000163462(gene)|ensembl:ENST00000334634(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001764"(neuron migration)|interpro:IPR027370|interpro:IPR035731|interpro:IPR036116|interpro:IPR040859|interpro:IPR043136|reactome:R-HSA-877300|go:"GO:0005856"(cytoskeleton)|go:"GO:0007409"(axonogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0043194"(axon initial segment)|go:"GO:0044304"(main axon)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0099612"(protein localization to axon)|go:"GO:1901953"(positive regulation of anterograde dense core granule transport)|go:"GO:1903827"|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990769"(proximal neuron projection)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|refseq:NP_001243528.1|refseq:NP_001243529.1|refseq:NP_001243530.1|refseq:NP_001269307.1|refseq:NP_001269308.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:onw4DUslrZLhQZp8FtqY6s6Q/u09606	rogid:Te5aeDC5aMKYNhajjekIRJCtzBQ9606	intact-crc:B9FFCF25E6D032F0|rigid:d/4vbVZBWT1wNOd5T7480fmzC8k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VVX9	uniprotkb:Q9C035	intact:EBI-2130181|uniprotkb:Q8N1D4|intact:EBI-28974117|ensembl:ENSP00000481174	intact:EBI-924214|uniprotkb:Q2MLV4|uniprotkb:Q2MLV8|uniprotkb:Q2MLV9|uniprotkb:Q2MLW1|uniprotkb:Q2MLW3|uniprotkb:Q2MLW4|uniprotkb:A6NGQ1|uniprotkb:Q2MLW6|uniprotkb:Q2MLW7|uniprotkb:Q2MLX1|uniprotkb:Q2MLX2|uniprotkb:Q2MLX3|uniprotkb:Q2MLX5|uniprotkb:Q2MLY3|uniprotkb:Q2MLY4|uniprotkb:Q2V6Q6|uniprotkb:Q6GX26|uniprotkb:Q8WU46|uniprotkb:Q96SR5|uniprotkb:Q9C031|uniprotkb:Q9C032|uniprotkb:Q9C033|uniprotkb:Q9C034|uniprotkb:A8WFA8|uniprotkb:D3DQS8|uniprotkb:D3DQS9|uniprotkb:G3GJY1|ensembl:ENSP00000369373|ensembl:ENSP00000507420	psi-mi:ube2u_human(display_long)|uniprotkb:UBE2U(gene name)|psi-mi:UBE2U(display_short)|uniprotkb:Ubiquitin-protein ligase U(gene name synonym)|uniprotkb:Ubiquitin carrier protein U(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme U(gene name synonym)	psi-mi:trim5_human(display_long)|uniprotkb:TRIM5(gene name)|psi-mi:TRIM5(display_short)|uniprotkb:RNF88(gene name synonym)|uniprotkb:RING finger protein 88(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342108|imex:IM-11696-538	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000371076|ensembl:ENSP00000360116|ensembl:ENSP00000481174|refseq:NP_689702.1|ensembl:ENSG00000177414(gene)|ensembl:ENST00000611228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033503"(HULC complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YRV|reactome:R-HSA-983168	refseq:NP_149023.2|refseq:NP_149083.2|refseq:NP_149084.2|refseq:XP_011518729.1|refseq:XP_005253240.1|refseq:XP_005253241.1|ensembl:ENSG00000132256(gene)|ensembl:ENST00000380034(transcript)|ensembl:ENST00000684655(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031664"(regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR043136|rcsb pdb:2ECV|rcsb pdb:2YRG|reactome:R-HSA-877300	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:onw4DUslrZLhQZp8FtqY6s6Q/u09606	rogid:t0YqhaJC8oQcwot7oks1LgMxdNc9606	intact-crc:E1C76C6DC72F7995|rigid:ThBAykfn4/3OSTcP8X75kbkQCh8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BYE7	uniprotkb:Q5VVX9	intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862	intact:EBI-2130181|uniprotkb:Q8N1D4|intact:EBI-28974117|ensembl:ENSP00000481174	psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym)	psi-mi:ube2u_human(display_long)|uniprotkb:UBE2U(gene name)|psi-mi:UBE2U(display_short)|uniprotkb:Ubiquitin-protein ligase U(gene name synonym)|uniprotkb:Ubiquitin carrier protein U(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme U(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342105|imex:IM-11696-537	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N	ensembl:ENST00000371076|ensembl:ENSP00000360116|ensembl:ENSP00000481174|refseq:NP_689702.1|ensembl:ENSG00000177414(gene)|ensembl:ENST00000611228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033503"(HULC complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YRV|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606	rogid:onw4DUslrZLhQZp8FtqY6s6Q/u09606	intact-crc:9FA6C7992DCE8083|rigid:womgpi1Yfn6w9bgTC/DOYroyzJg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z419	uniprotkb:Q5VVX9	intact:EBI-2129982|uniprotkb:B3KUA8|uniprotkb:Q5TB85|uniprotkb:Q6P4Q0|uniprotkb:Q8N3R7|uniprotkb:Q9BX38|uniprotkb:B4DZI2|ensembl:ENSP00000259939	intact:EBI-2130181|uniprotkb:Q8N1D4|intact:EBI-28974117|ensembl:ENSP00000481174	psi-mi:r144b_human(display_long)|uniprotkb:RNF144B(gene name)|psi-mi:RNF144B(display_short)|uniprotkb:IBRDC2(gene name synonym)|uniprotkb:P53RFP(gene name synonym)|uniprotkb:RING finger protein 144B(gene name synonym)|uniprotkb:IBR domain-containing protein 2(gene name synonym)|uniprotkb:p53-inducible RING finger protein(gene name synonym)	psi-mi:ube2u_human(display_long)|uniprotkb:UBE2U(gene name)|psi-mi:UBE2U(display_short)|uniprotkb:Ubiquitin-protein ligase U(gene name synonym)|uniprotkb:Ubiquitin carrier protein U(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme U(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342121|imex:IM-11696-540	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_877434.2|dip:DIP-43771N|ensembl:ENSG00000137393(gene)|ensembl:ENST00000259939(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168	ensembl:ENST00000371076|ensembl:ENSP00000360116|ensembl:ENSP00000481174|refseq:NP_689702.1|ensembl:ENSG00000177414(gene)|ensembl:ENST00000611228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033503"(HULC complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YRV|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:Ep53jYpmEeClpBZYNkPKrQgy/0A9606	rogid:onw4DUslrZLhQZp8FtqY6s6Q/u09606	intact-crc:31AAE0DDB397B7EF|rigid:OciqWyYmdlW0n88D5uH7Hlsww9A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C019	uniprotkb:Q5VVX9	intact:EBI-2342111|uniprotkb:Q9C018|uniprotkb:O95604|uniprotkb:Q8IUX9|uniprotkb:A2BEC9|ensembl:ENSP00000259930|ensembl:ENSP00000365884|ensembl:ENSP00000403221|ensembl:ENSP00000411683|ensembl:ENSP00000413961|ensembl:ENSP00000415480	intact:EBI-2130181|uniprotkb:Q8N1D4|intact:EBI-28974117|ensembl:ENSP00000481174	psi-mi:tri15_human(display_long)|uniprotkb:TRIM15(gene name)|psi-mi:TRIM15(display_short)|uniprotkb:RNF93(gene name synonym)|uniprotkb:ZNF178(gene name synonym)|uniprotkb:ZNFB7(gene name synonym)|uniprotkb:Zinc finger protein B7(gene name synonym)|uniprotkb:RING finger protein 93(gene name synonym)|uniprotkb:Zinc finger protein 178(gene name synonym)	psi-mi:ube2u_human(display_long)|uniprotkb:UBE2U(gene name)|psi-mi:UBE2U(display_short)|uniprotkb:Ubiquitin-protein ligase U(gene name synonym)|uniprotkb:Ubiquitin carrier protein U(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme U(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342118|imex:IM-11696-539	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_150232.2|ensembl:ENSG00000137384(gene)|ensembl:ENSG00000204610(gene)|ensembl:ENSG00000227147(gene)|ensembl:ENSG00000233599(gene)|ensembl:ENSG00000235259(gene)|ensembl:ENSG00000235960(gene)|ensembl:ENST00000259930(transcript)|ensembl:ENST00000376694(transcript)|ensembl:ENST00000414873(transcript)|ensembl:ENST00000421984(transcript)|ensembl:ENST00000427091(transcript)|ensembl:ENST00000431059(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0045087"(innate immune response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR018957|interpro:IPR043136	ensembl:ENST00000371076|ensembl:ENSP00000360116|ensembl:ENSP00000481174|refseq:NP_689702.1|ensembl:ENSG00000177414(gene)|ensembl:ENST00000611228(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033503"(HULC complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1YRV|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:W8K5SsgQmtSbl6MPUPA4bF4nd6k9606	rogid:onw4DUslrZLhQZp8FtqY6s6Q/u09606	intact-crc:C640BEBA42BDF1DA|rigid:5JkheqgJ5p83qOEit/H6zfPszPg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IWF7	uniprotkb:Q8N9I9	intact:EBI-2340154	intact:EBI-2340258|uniprotkb:Q8NDS8|uniprotkb:Q8NAU6|uniprotkb:Q53ZZ2|ensembl:ENSP00000338050|ensembl:ENSP00000447873|ensembl:ENSP00000449294	psi-mi:u2d2l_human(display_long)|uniprotkb:UBE2DNL(gene name)|psi-mi:UBE2DNL(display_short)|uniprotkb:UBE2D2L(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2-like(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2-like(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2D N-terminal-like(gene name synonym)	psi-mi:dtx3_human(display_long)|uniprotkb:DTX3(gene name)|psi-mi:DTX3(display_short)|uniprotkb:RNF154(gene name synonym)|uniprotkb:RING finger protein 154(gene name synonym)|uniprotkb:Protein deltex-3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342124|imex:IM-11696-541	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)	refseq:NP_001273174.1|refseq:NP_001273175.1|refseq:XP_011536324.1|refseq:NP_848597.1|refseq:XP_005268754.1|refseq:XP_005268755.1|refseq:XP_005268757.1|refseq:XP_005268760.1|ensembl:ENSG00000178498(gene)|ensembl:ENST00000337737(transcript)|ensembl:ENST00000548198(transcript)|ensembl:ENST00000548804(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/05/08	2014/10/16	rogid:ZSC3lfWt9Fx/FDRYJO3WbVWn4Bs9606	rogid:Ma7JBhgMdFofCeWESbf8h1iLAHY9606	intact-crc:F7C932DBFEC4ECC4|rigid:qDiGhmnoqpNN8RLgcFMr8NCDCNQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51668	uniprotkb:Q8ND25	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342127|imex:IM-11696-568	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	intact-crc:963595819170CBD9|rigid:PJ3OdNj18WEVNReY3L2/OaMKAkw	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y4K3	uniprotkb:P61088	intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|ensembl:ENSP00000337853|ensembl:ENSP00000433623|uniprotkb:D3DR16	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342131|imex:IM-11696-577	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004611.1|refseq:NP_665802.1|ensembl:ENSG00000175104(gene)|ensembl:ENST00000348124(transcript)|ensembl:ENST00000526995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|go:"GO:0070534"(protein K63-linked ubiquitination)|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|go:"GO:0070555"(response to interleukin-1)|rcsb pdb:7L3L|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|go:"GO:0071222"(cellular response to lipopolysaccharide)|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-975871|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|dip:DIP-27515N	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	intact-crc:F1FFB9FFB33A64E7|rigid:rTuhyeFjBYVdR/fADCmNcLvYga0	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y4K3	uniprotkb:Q13404	intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|ensembl:ENSP00000337853|ensembl:ENSP00000433623|uniprotkb:D3DR16	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342135|imex:IM-11696-575	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004611.1|refseq:NP_665802.1|ensembl:ENSG00000175104(gene)|ensembl:ENST00000348124(transcript)|ensembl:ENST00000526995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|go:"GO:0070534"(protein K63-linked ubiquitination)|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|go:"GO:0070555"(response to interleukin-1)|rcsb pdb:7L3L|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|go:"GO:0071222"(cellular response to lipopolysaccharide)|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-975871|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|dip:DIP-27515N	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	intact-crc:3E9C3E3DA59B9EC0|rigid:Ix1zIdXL953GzkBOZ4WE/pdZ6XI	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y4K3	uniprotkb:P61088	intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|ensembl:ENSP00000337853|ensembl:ENSP00000433623|uniprotkb:D3DR16	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342135|imex:IM-11696-575	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004611.1|refseq:NP_665802.1|ensembl:ENSG00000175104(gene)|ensembl:ENST00000348124(transcript)|ensembl:ENST00000526995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|go:"GO:0070534"(protein K63-linked ubiquitination)|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|go:"GO:0070555"(response to interleukin-1)|rcsb pdb:7L3L|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|go:"GO:0071222"(cellular response to lipopolysaccharide)|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-975871|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|dip:DIP-27515N	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	intact-crc:3E9C3E3DA59B9EC0|rigid:Ix1zIdXL953GzkBOZ4WE/pdZ6XI	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y4K3	uniprotkb:P51668	intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|ensembl:ENSP00000337853|ensembl:ENSP00000433623|uniprotkb:D3DR16	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342139|imex:IM-11696-563	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004611.1|refseq:NP_665802.1|ensembl:ENSG00000175104(gene)|ensembl:ENST00000348124(transcript)|ensembl:ENST00000526995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|go:"GO:0070534"(protein K63-linked ubiquitination)|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|go:"GO:0070555"(response to interleukin-1)|rcsb pdb:7L3L|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|go:"GO:0071222"(cellular response to lipopolysaccharide)|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-975871|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|dip:DIP-27515N	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:54B9345CB33A67FA|rigid:1Xk3CbTQEwdXwrSFAN+Nn1HY/Iw	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P62837	uniprotkb:Q9Y4K3	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|ensembl:ENSP00000337853|ensembl:ENSP00000433623|uniprotkb:D3DR16	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342143|imex:IM-11696-574	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_004611.1|refseq:NP_665802.1|ensembl:ENSG00000175104(gene)|ensembl:ENST00000348124(transcript)|ensembl:ENST00000526995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|go:"GO:0070534"(protein K63-linked ubiquitination)|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|go:"GO:0070555"(response to interleukin-1)|rcsb pdb:7L3L|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|go:"GO:0071222"(cellular response to lipopolysaccharide)|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-975871|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|dip:DIP-27515N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606	intact-crc:417A1AFFB33923A3|rigid:3h2mtmZQ+C9QPvD+GhtKkr1zcgk	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61077	uniprotkb:Q9Y4K3	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|ensembl:ENSP00000337853|ensembl:ENSP00000433623|uniprotkb:D3DR16	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342147|imex:IM-11696-561	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	refseq:NP_004611.1|refseq:NP_665802.1|ensembl:ENSG00000175104(gene)|ensembl:ENST00000348124(transcript)|ensembl:ENST00000526995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|go:"GO:0070534"(protein K63-linked ubiquitination)|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|go:"GO:0070555"(response to interleukin-1)|rcsb pdb:7L3L|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|go:"GO:0071222"(cellular response to lipopolysaccharide)|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-975871|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|dip:DIP-27515N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606	intact-crc:0EFFB9FFB33922C4|rigid:gAlEObvOnJR0Dw33XC1VKMcErGk	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y4K3	uniprotkb:P51965	intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|ensembl:ENSP00000337853|ensembl:ENSP00000433623|uniprotkb:D3DR16	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342151|imex:IM-11696-562	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004611.1|refseq:NP_665802.1|ensembl:ENSG00000175104(gene)|ensembl:ENST00000348124(transcript)|ensembl:ENST00000526995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|go:"GO:0070534"(protein K63-linked ubiquitination)|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|go:"GO:0070555"(response to interleukin-1)|rcsb pdb:7L3L|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|go:"GO:0071222"(cellular response to lipopolysaccharide)|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-975871|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|dip:DIP-27515N	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	intact-crc:C3A84905D875D524|rigid:ZO0ms8jhKTBgJZ+IUEVWcWI/YnI	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y3C5	uniprotkb:Q13404	intact:EBI-396669|intact:EBI-2129167|uniprotkb:A8KAI2|uniprotkb:Q5T7R8|ensembl:ENSP00000242719	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	psi-mi:rnf11_human(display_long)|uniprotkb:CGI-123(orf name)|uniprotkb:RNF11(gene name)|psi-mi:RNF11(display_short)	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342155|imex:IM-11696-572	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055187.1|ensembl:ENSP00000242719|ensembl:ENSG00000123091(gene)|ensembl:ENST00000242719(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042981|mint:Q9Y3C5	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:Uj0YAf/t+AdYbMd6fgQ8hVKoP0w9606	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	intact-crc:006523FB5EB74432|rigid:1KNNFisnfH7WeE3Ix2Rd4HO8nwc	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y3C5	uniprotkb:P61088	intact:EBI-396669|intact:EBI-2129167|uniprotkb:A8KAI2|uniprotkb:Q5T7R8|ensembl:ENSP00000242719	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	psi-mi:rnf11_human(display_long)|uniprotkb:CGI-123(orf name)|uniprotkb:RNF11(gene name)|psi-mi:RNF11(display_short)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342155|imex:IM-11696-572	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055187.1|ensembl:ENSP00000242719|ensembl:ENSG00000123091(gene)|ensembl:ENST00000242719(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042981|mint:Q9Y3C5	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:Uj0YAf/t+AdYbMd6fgQ8hVKoP0w9606	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	intact-crc:006523FB5EB74432|rigid:1KNNFisnfH7WeE3Ix2Rd4HO8nwc	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13404	uniprotkb:P61088	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342159|imex:IM-11696-565	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	intact-crc:19DE859B2915B22A|rigid:N/f/aDg0ieWWnr6bLHgROLdIowE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13404	uniprotkb:P98170	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342159|imex:IM-11696-565	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	intact-crc:19DE859B2915B22A|rigid:N/f/aDg0ieWWnr6bLHgROLdIowE	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13404	uniprotkb:P61088	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342174|imex:IM-11696-570	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	intact-crc:202EE2B9EC9D7780|rigid:lqo2AqJeNe2FrUJvaGr4c0svrj0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13404	uniprotkb:Q8ND25	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342174|imex:IM-11696-570	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	intact-crc:202EE2B9EC9D7780|rigid:lqo2AqJeNe2FrUJvaGr4c0svrj0	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8ND25	uniprotkb:P49427	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	intact:EBI-975634|ensembl:ENSP00000215574|uniprotkb:A8K689	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:ub2r1_human(display_long)|uniprotkb:Ubiquitin-protein ligase R1(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-32 kDa complementing(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-CDC34(gene name synonym)|uniprotkb:CDC34(gene name)|psi-mi:CDC34(display_short)|uniprotkb:UBE2R1(gene name synonym)|uniprotkb:UBCH3(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme R1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme R1(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342178|imex:IM-11696-567	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070848"(response to growth factor)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090261"(positive regulation of inclusion body assembly)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2OB4|rcsb pdb:3RZ3|rcsb pdb:4MDK|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-983168|ensembl:ENSG00000099804(gene)|ensembl:ENST00000215574(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:NP_004350.1|dip:DIP-37783N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	rogid:iOYLaiXBmINnd0daIWCr5KVungo9606	intact-crc:372CE6E091738FDA|rigid:Al9sLNyVj1IgH8QO3RkQPUutGJA	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P62837	uniprotkb:Q8ND25	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342282|imex:IM-11696-564	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	intact-crc:5FC8C67BFA3FCAE3|rigid:s+LFkHsZf1nUxmTPCbLhyDRZrW4	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51965	uniprotkb:Q8ND25	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-2129250|uniprotkb:Q9H083|uniprotkb:D3DUJ9|ensembl:ENSP00000335091|ensembl:ENSP00000455601	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:znrf1_human(display_long)|uniprotkb:ZNRF1(gene name)|psi-mi:ZNRF1(display_short)|uniprotkb:NIN283(gene name synonym)|uniprotkb:Zinc/RING finger protein 1(gene name synonym)|uniprotkb:Nerve injury-induced gene 283 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF1(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342289|imex:IM-11696-566	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_115644.1|refseq:XP_016879282.1|ensembl:ENSG00000186187(gene)|ensembl:ENST00000335325(transcript)|ensembl:ENST00000567962(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:5YWR|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:hHvuiy8EDttn/pxjkRR+VsXMcBA9606	intact-crc:0124E8D8FA3F7907|rigid:74CD2YeFhCluQGTEJedBmRKBOPw	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61088	uniprotkb:P98170	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342296|imex:IM-11696-557	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	intact-crc:AD739ED06F61FB42|rigid:FmuIDEvRIJL0Zg+Djd5bArd6dCY	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51668	uniprotkb:P98170	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342301|imex:IM-11696-569	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	intact-crc:083513736F61F85F|rigid:5eZRZPj/O/2HT1a8GJTN4KSK50U	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P98170	uniprotkb:P62837	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342307|imex:IM-11696-573	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:1DF63DD06F62BC06|rigid:10Ir6LnSgk/UcwH8Sn46RYoNIwk	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P98170	uniprotkb:P61077	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342312|imex:IM-11696-560	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:52739ED06F62BD61|rigid:gL2RfBy1oyIDMiIgYmf+ehuqNrg	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51965	uniprotkb:P98170	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342317|imex:IM-11696-571	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	intact-crc:431A13736F620FE2|rigid:pQKhi+g/ql/FBppf/jUb5yuCKv4	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51668	uniprotkb:Q9Y3C5	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	intact:EBI-396669|intact:EBI-2129167|uniprotkb:A8KAI2|uniprotkb:Q5T7R8|ensembl:ENSP00000242719	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:rnf11_human(display_long)|uniprotkb:CGI-123(orf name)|uniprotkb:RNF11(gene name)|psi-mi:RNF11(display_short)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342322|imex:IM-11696-576	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	refseq:NP_055187.1|ensembl:ENSP00000242719|ensembl:ENSG00000123091(gene)|ensembl:ENST00000242719(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042981|mint:Q9Y3C5	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rogid:Uj0YAf/t+AdYbMd6fgQ8hVKoP0w9606	intact-crc:6A40299A4816BD08|rigid:8KJCHvUBv0bUNe/fIMo7U/wdU/4	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y3C5	uniprotkb:P62837	intact:EBI-396669|intact:EBI-2129167|uniprotkb:A8KAI2|uniprotkb:Q5T7R8|ensembl:ENSP00000242719	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:rnf11_human(display_long)|uniprotkb:CGI-123(orf name)|uniprotkb:RNF11(gene name)|psi-mi:RNF11(display_short)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342327|imex:IM-11696-578	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055187.1|ensembl:ENSP00000242719|ensembl:ENSG00000123091(gene)|ensembl:ENST00000242719(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042981|mint:Q9Y3C5	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:Uj0YAf/t+AdYbMd6fgQ8hVKoP0w9606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:7F8307394815F951|rigid:RDLiR+M2V+bH5mdKpAzKPr37IWQ	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y3C5	uniprotkb:P61077	intact:EBI-396669|intact:EBI-2129167|uniprotkb:A8KAI2|uniprotkb:Q5T7R8|ensembl:ENSP00000242719	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:rnf11_human(display_long)|uniprotkb:CGI-123(orf name)|uniprotkb:RNF11(gene name)|psi-mi:RNF11(display_short)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342332|imex:IM-11696-558	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055187.1|ensembl:ENSP00000242719|ensembl:ENSG00000123091(gene)|ensembl:ENST00000242719(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042981|mint:Q9Y3C5	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:Uj0YAf/t+AdYbMd6fgQ8hVKoP0w9606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:3006A4394815F836|rigid:AlTDSwn1f4OdjIMaEZu3NBsTL/4	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51965	uniprotkb:Q9Y3C5	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	intact:EBI-396669|intact:EBI-2129167|uniprotkb:A8KAI2|uniprotkb:Q5T7R8|ensembl:ENSP00000242719	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:rnf11_human(display_long)|uniprotkb:CGI-123(orf name)|uniprotkb:RNF11(gene name)|psi-mi:RNF11(display_short)	psi-mi:"MI:0415"(enzymatic study)	Markson et al. (2009)	imex:IM-11696|pubmed:19549727	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0220"(ubiquitination reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2342337|imex:IM-11696-559	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	refseq:NP_055187.1|ensembl:ENSP00000242719|ensembl:ENSG00000123091(gene)|ensembl:ENST00000242719(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042981|mint:Q9Y3C5	psi-mi:"MI:0469"(intact)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/08	2014/10/16	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rogid:Uj0YAf/t+AdYbMd6fgQ8hVKoP0w9606	intact-crc:216F299A48154AB5|rigid:5xooB0iEpHyvn/Fuwzvpwb2iCkI	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)