#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q08509 uniprotkb:O43813 intact:EBI-375596|uniprotkb:Q3TM41|ensembl:ENSMUSP00000052776|ensembl:ENSMUSP00000098402|ensembl:ENSMUSP00000107509 intact:EBI-3046631|ensembl:ENSP00000233714|ensembl:ENSP00000388713|ensembl:ENSP00000393323|ensembl:ENSP00000393597|ensembl:ENSP00000397646 psi-mi:eps8_mouse(display_long)|uniprotkb:Eps8(gene name)|psi-mi:Eps8(display_short) psi-mi:lanc1_human(display_long)|uniprotkb:LANCL1(gene name)|psi-mi:LANCL1(display_short)|uniprotkb:GPR69A(gene name synonym)|uniprotkb:40 kDa erythrocyte membrane protein(gene name synonym)|uniprotkb:LanC-like protein 1(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Zhang et al. (2009) pubmed:19528316|mint:MINT-7213578|doi:10.1101/gad.1789209 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7061204|mint:MINT-7215805 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010458"(exit from mitosis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0030426"(growth cone)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0045202"(synapse)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030222|interpro:IPR033928|interpro:IPR035462|interpro:IPR036028|interpro:IPR039801|interpro:IPR041418|mint:Q08509|rcsb pdb:1AOJ|rcsb pdb:1I07|rcsb pdb:1I0C|ensembl:ENSMUSG00000015766(gene)|ensembl:ENSMUST00000058210(transcript)|ensembl:ENSMUST00000100841(transcript)|ensembl:ENSMUST00000111878(transcript)|refseq:NP_031971.2|refseq:NP_001258524.1|refseq:NP_001258517.1|refseq:NP_001258516.1|refseq:NP_001258518.1|refseq:XP_011239506.1|dip:DIP-32858N|mint:MINT-7215808(identity) ensembl:ENSG00000115365(gene)|ensembl:ENST00000233714(transcript)|ensembl:ENST00000431941(transcript)|ensembl:ENST00000441020(transcript)|ensembl:ENST00000443314(transcript)|ensembl:ENST00000450366(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043295"(glutathione binding)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:1903203"(regulation of oxidative stress-induced neuron death)|interpro:IPR007822(Lanthionine synthetase C-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR020464|mint:O43813|rcsb pdb:3E6U|rcsb pdb:3E73|refseq:NP_001130046.1|refseq:NP_001130047.1|refseq:NP_006046.1|mint:MINT-7215807(identity) - - - figure legend:f3a|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:0.6x10^-6(molar) 2009/07/06 2014/10/16 rogid:glTI+FSRPZ3apY8RGGDdMI6ialw10090 rogid:em3J/MvBGB1LZ0X1QFagwWBk5FQ9606 intact-crc:18A7B175C435AA59|rigid:raz3EzYCDXJiDv5G7+ZytQChr18 false binding-associated region:532-591(MINT-7215830) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NS86 uniprotkb:Q08509 intact:EBI-2510837|ensembl:ENSP00000254770|uniprotkb:Q8TCQ3|uniprotkb:Q9BSR1|uniprotkb:B2R8D4|uniprotkb:Q6NSL4 intact:EBI-375596|uniprotkb:Q3TM41|ensembl:ENSMUSP00000052776|ensembl:ENSMUSP00000098402|ensembl:ENSMUSP00000107509 psi-mi:lanc2_human(display_long)|uniprotkb:LANCL2(gene name)|psi-mi:LANCL2(display_short)|uniprotkb:GPR69B(gene name synonym)|uniprotkb:TASP(gene name synonym)|uniprotkb:Testis-specific adriamycin sensitivity protein(gene name synonym) psi-mi:eps8_mouse(display_long)|uniprotkb:Eps8(gene name)|psi-mi:Eps8(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Zhang et al. (2009) pubmed:19528316|mint:MINT-7213578|doi:10.1101/gad.1789209 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7061256|mint:MINT-7215834 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132434(gene)|ensembl:ENST00000254770(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0009789"(positive regulation of abscisic acid-activated signaling pathway)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|interpro:IPR007822(Lanthionine synthetase C-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR020464|mint:Q9NS86|rcsb pdb:6WQ1|refseq:NP_061167.1|mint:MINT-7215842(identity) go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010458"(exit from mitosis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0030426"(growth cone)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0045202"(synapse)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030222|interpro:IPR033928|interpro:IPR035462|interpro:IPR036028|interpro:IPR039801|interpro:IPR041418|mint:Q08509|rcsb pdb:1AOJ|rcsb pdb:1I07|rcsb pdb:1I0C|ensembl:ENSMUSG00000015766(gene)|ensembl:ENSMUST00000058210(transcript)|ensembl:ENSMUST00000100841(transcript)|ensembl:ENSMUST00000111878(transcript)|refseq:NP_031971.2|refseq:NP_001258524.1|refseq:NP_001258517.1|refseq:NP_001258516.1|refseq:NP_001258518.1|refseq:XP_011239506.1|dip:DIP-32858N|mint:MINT-7215837(identity) - - - figure legend:f3b|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:0.45x10^-6(molar) 2009/07/06 2014/10/16 rogid:PkzdkGLvNrypmS0AERzZANWFPZ09606 rogid:glTI+FSRPZ3apY8RGGDdMI6ialw10090 intact-crc:ABFD12C9CFD09FE9|rigid:yi8Dz47LUNUtUBf/YdjXjs+Ah1o false - binding-associated region:532-591(MINT-7215838) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43813 uniprotkb:Q08509 intact:EBI-3046631|ensembl:ENSP00000233714|ensembl:ENSP00000388713|ensembl:ENSP00000393323|ensembl:ENSP00000393597|ensembl:ENSP00000397646 intact:EBI-375596|uniprotkb:Q3TM41|ensembl:ENSMUSP00000052776|ensembl:ENSMUSP00000098402|ensembl:ENSMUSP00000107509 psi-mi:lanc1_human(display_long)|uniprotkb:LANCL1(gene name)|psi-mi:LANCL1(display_short)|uniprotkb:GPR69A(gene name synonym)|uniprotkb:40 kDa erythrocyte membrane protein(gene name synonym)|uniprotkb:LanC-like protein 1(gene name synonym) psi-mi:eps8_mouse(display_long)|uniprotkb:Eps8(gene name)|psi-mi:Eps8(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Zhang et al. (2009) pubmed:19528316|mint:MINT-7213578|doi:10.1101/gad.1789209 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7061236|mint:MINT-7215813 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115365(gene)|ensembl:ENST00000233714(transcript)|ensembl:ENST00000431941(transcript)|ensembl:ENST00000441020(transcript)|ensembl:ENST00000443314(transcript)|ensembl:ENST00000450366(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043295"(glutathione binding)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:1903203"(regulation of oxidative stress-induced neuron death)|interpro:IPR007822(Lanthionine synthetase C-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR020464|mint:O43813|rcsb pdb:3E6U|rcsb pdb:3E73|refseq:NP_001130046.1|refseq:NP_001130047.1|refseq:NP_006046.1|mint:MINT-7215817(identity) go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010458"(exit from mitosis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0030426"(growth cone)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0045202"(synapse)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030222|interpro:IPR033928|interpro:IPR035462|interpro:IPR036028|interpro:IPR039801|interpro:IPR041418|mint:Q08509|rcsb pdb:1AOJ|rcsb pdb:1I07|rcsb pdb:1I0C|ensembl:ENSMUSG00000015766(gene)|ensembl:ENSMUST00000058210(transcript)|ensembl:ENSMUST00000100841(transcript)|ensembl:ENSMUST00000111878(transcript)|refseq:NP_031971.2|refseq:NP_001258524.1|refseq:NP_001258517.1|refseq:NP_001258516.1|refseq:NP_001258518.1|refseq:XP_011239506.1|dip:DIP-32858N|mint:MINT-7215816(identity) - - - comment:homomint|comment:mint|figure legend:f3c f3d f3e|partial coverage:partial coverage|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:0.6x10^-6(molar) 2009/07/06 2014/10/16 rogid:em3J/MvBGB1LZ0X1QFagwWBk5FQ9606 rogid:glTI+FSRPZ3apY8RGGDdMI6ialw10090 intact-crc:C138FE726F10F00D|rigid:raz3EzYCDXJiDv5G7+ZytQChr18 false - glutathione s tranferase tag:?-?(MINT-7215849)|binding-associated region:532-591(MINT-7215823) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)