#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8BH75 uniprotkb:Q80U87 intact:EBI-7059583|ensembl:ENSMUSP00000100869|ensembl:ENSMUSP00000132751|uniprotkb:Q9CRK6|uniprotkb:Q8BMC9|uniprotkb:Q8VEA2|uniprotkb:Q9D568|uniprotkb:Q8BGJ2|intact:MINT-7148521 intact:EBI-1765959|uniprotkb:Q80YP2|uniprotkb:Q8R0D3|uniprotkb:Q9EQU1|uniprotkb:Q9WVP5|uniprotkb:A2AI53|ensembl:ENSMUSP00000028841 psi-mi:rnf41_mouse(display_long)|uniprotkb:Rnf41(gene name)|psi-mi:Rnf41(display_short)|uniprotkb:Flrf(gene name synonym)|uniprotkb:Nrdp1(gene name synonym)|uniprotkb:RING finger protein 41(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NRDP1(gene name synonym) psi-mi:ubp8_mouse(display_long)|uniprotkb:Usp8(gene name)|psi-mi:Usp8(display_short)|uniprotkb:Kiaa0055(gene name synonym)|uniprotkb:Ubpy(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 8(gene name synonym)|uniprotkb:Deubiquitinating enzyme 8(gene name synonym)|uniprotkb:Ubiquitin isopeptidase Y(gene name synonym)|uniprotkb:Ubiquitin thioesterase 8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sippel et al. (2009) pubmed:19527720|mint:MINT-7148516|mint:d-09-00984|doi:10.1016/j.febslet.2009.06.018 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7059579|mint:MINT-7148555 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025373(gene)|ensembl:ENSMUST00000096386(transcript)|ensembl:ENSMUST00000171342(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005128"(erythropoietin receptor binding)|go:"GO:0005135"(interleukin-3 receptor binding)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015036(USP8 interacting)|interpro:IPR017907|interpro:IPR037255|mint:Q8BH75|rcsb pdb:2OGB|reactome:R-MMU-1358803|reactome:R-MMU-983168|refseq:NP_080535.2|refseq:NP_001157709.1|mint:MINT-7148557(identity) refseq:NP_062703.2|ensembl:ENSMUST00000028841(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030496"(midbody)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043197"(dendritic spine)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR015063(Region of unknown function DUF1873)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|mint:Q80U87|rcsb pdb:1UJ0|reactome:R-MMU-1358803|reactome:R-MMU-4641263|reactome:R-MMU-5689880|reactome:R-MMU-6807004|ensembl:ENSMUSG00000027363(gene)|mint:MINT-7148558(identity) - comment:mint - comment:mint|figure legend:F4E taxid:10090(mouse)|taxid:10090(Mus musculus) - 2009/06/09 2014/10/16 rogid:XuXdxBbSRJdvzSDnTev8GQIAI6E10090 rogid:PhHue+cov/Z/PGJqR8RtRQF6qco10090 intact-crc:F4C0128217A8E744|rigid:2at0oincI289WhKBKpjdYIJyn9E false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BH75 uniprotkb:O88738 intact:EBI-7059583|ensembl:ENSMUSP00000100869|ensembl:ENSMUSP00000132751|uniprotkb:Q9CRK6|uniprotkb:Q8BMC9|uniprotkb:Q8VEA2|uniprotkb:Q9D568|uniprotkb:Q8BGJ2|intact:MINT-7148521 intact:EBI-912068|uniprotkb:E9PYU6|uniprotkb:Q69ZM5|uniprotkb:Q8BNX0|uniprotkb:Q8BR72|uniprotkb:Q8BRV7|uniprotkb:Q8C737|ensembl:ENSMUSP00000138333 psi-mi:rnf41_mouse(display_long)|uniprotkb:Rnf41(gene name)|psi-mi:Rnf41(display_short)|uniprotkb:Flrf(gene name synonym)|uniprotkb:Nrdp1(gene name synonym)|uniprotkb:RING finger protein 41(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NRDP1(gene name synonym) psi-mi:birc6_mouse(display_long)|uniprotkb:Birc6(gene name)|psi-mi:Birc6(display_short)|uniprotkb:BIR repeat-containing ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:Kiaa1289(gene name synonym)|uniprotkb:Ubiquitin-conjugating BIR domain enzyme apollon(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sippel et al. (2009) pubmed:19527720|mint:MINT-7148516|mint:d-09-00984|doi:10.1016/j.febslet.2009.06.018 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7059647|mint:MINT-7148564 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025373(gene)|ensembl:ENSMUST00000096386(transcript)|ensembl:ENSMUST00000171342(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005128"(erythropoietin receptor binding)|go:"GO:0005135"(interleukin-3 receptor binding)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015036(USP8 interacting)|interpro:IPR017907|interpro:IPR037255|mint:Q8BH75|rcsb pdb:2OGB|reactome:R-MMU-1358803|reactome:R-MMU-983168|refseq:NP_080535.2|refseq:NP_001157709.1|mint:MINT-7148566(identity) refseq:NP_031592.3|ensembl:ENSMUSG00000024073(gene)|ensembl:ENSMUST00000182597(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001890"(placenta development)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051301"(cell division)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:0060712"(spongiotrophoblast layer development)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0090543"(Flemming body)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR022103|interpro:IPR036322|mint:O88738|mint:MINT-7148568(identity) - comment:mint - comment:mint|figure legend:F4E taxid:10090(mouse)|taxid:10090(Mus musculus) - 2009/06/09 2014/10/16 rogid:XuXdxBbSRJdvzSDnTev8GQIAI6E10090 rogid:Pa62v6xd4WQNOHRL5c+Wo8gf5wo10090 intact-crc:09351B3CB4FD3605|rigid:apGhS/V9YLX+avZUo/Hyi/C3bzY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)