#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P12497-PRO_0000042395 uniprotkb:P12497-PRO_0000042395 intact:EBI-2369107 intact:EBI-2369107 psi-mi:p12497-pro_0000042395(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:p12497-pro_0000042395(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Pornillos et al. (2009) imex:IM-12198|pubmed:19523676 taxid:11698(hv1n5)|taxid:11698("Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)") taxid:11698(hv1n5)|taxid:11698("Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2369110|imex:IM-12198-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1026248(chain-parent) intact:EBI-1026248(chain-parent) go:"GO:0051259"(protein complex oligomerization) chain-seq-start:133|chain-seq-end:363 chain-seq-start:133|chain-seq-end:363 figure legend:Fig. 1A-C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/07/27 2014/10/16 rogid:5u/G2V/o1swaXMUhq12aJv7SZBA11698 rogid:5u/G2V/o1swaXMUhq12aJv7SZBA11698 intact-crc:D36C52D9F4C56DF7|rigid:pUpNe6QrCLWzKs0adiZmHL8B2K0 false mutation:14-14,45-45|mutation:45-45,14-14,184-185 mutation:14-14,45-45|mutation:45-45,14-14,184-185 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12497-PRO_0000042395 uniprotkb:P12497-PRO_0000042395 intact:EBI-2369107 intact:EBI-2369107 psi-mi:p12497-pro_0000042395(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:p12497-pro_0000042395(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Pornillos et al. (2009) imex:IM-12198|pubmed:19523676 taxid:11698(hv1n5)|taxid:11698("Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)") taxid:11698(hv1n5)|taxid:11698("Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2369130|imex:IM-12198-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1026248(chain-parent) intact:EBI-1026248(chain-parent) go:"GO:0051259"(protein complex oligomerization) chain-seq-start:133|chain-seq-end:363 chain-seq-start:133|chain-seq-end:363 figure legend:Fig. 1D-E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/07/27 2014/10/16 rogid:5u/G2V/o1swaXMUhq12aJv7SZBA11698 rogid:5u/G2V/o1swaXMUhq12aJv7SZBA11698 intact-crc:8EF0FAD433994613|rigid:pUpNe6QrCLWzKs0adiZmHL8B2K0 false mutation:14-14,184-185|mutation:45-45,14-14 mutation:14-14,184-185|mutation:45-45,14-14 6 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12497-PRO_0000042395 uniprotkb:P12497-PRO_0000042395 intact:EBI-2369107 intact:EBI-2369107 psi-mi:p12497-pro_0000042395(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:p12497-pro_0000042395(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Pornillos et al. (2009) imex:IM-12198|pubmed:19523676 taxid:11698(hv1n5)|taxid:11698("Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)") taxid:11698(hv1n5)|taxid:11698("Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2369147|wwpdb:3gv2|wwpdb:3h47|wwpdb:3h4e|imex:IM-12198-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1026248(chain-parent) intact:EBI-1026248(chain-parent) go:"GO:0051259"(protein complex oligomerization) chain-seq-start:133|chain-seq-end:363 chain-seq-start:133|chain-seq-end:363 figure legend:Table 1|comment:"The protein was synthesesed as a fusion protein with residues 1-112 of Synechocystis Ccmk4 (P73407) present at the C-terminal however Ccmk4 was not visible in the crystal so has not been annotated as part of the sequence."|comment:Three crystal forms were deposited with wwPDB. All 3 have been cross-referenced to this entry but only the details of the most highly refined have been annotated.|3d-resolution:1.9A|3d-r-factors:"Working: 23.42%, Free: 26.95%"|3d-structure:A ring of six p24 capsid protein N-terminal domains form an apparently rigid core, surrounded by an outer ring of C-terminal domains.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/07/27 2014/10/16 rogid:5u/G2V/o1swaXMUhq12aJv7SZBA11698 rogid:5u/G2V/o1swaXMUhq12aJv7SZBA11698 intact-crc:9240A20F88B66F74|rigid:pUpNe6QrCLWzKs0adiZmHL8B2K0 false mutation:14-14,184-185|sufficient binding region:1-226|fusion protein:c-c mutation:14-14,184-185|sufficient binding region:1-226|fusion protein:c-c 6 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)