#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8VHK2 uniprotkb:Q9NYB9 intact:EBI-7049475|intact:MINT-238952 intact:EBI-743598|uniprotkb:Q13147|uniprotkb:Q13249|uniprotkb:Q13801|uniprotkb:Q9BV70|uniprotkb:B4DSN1 psi-mi:cski1_rat(display_long)|uniprotkb:Caskin1(gene name)|psi-mi:Caskin1(display_short)|uniprotkb:CASK-interacting protein 1(gene name synonym) psi-mi:abi2_human(display_long)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym) psi-mi:"MI:0018"(two hybrid) Balázs et al. (2009) pubmed:19523119|mint:MINT-7034549|mint:fj-09-0215.r1 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7049470|mint:MINT-7034579 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q8VHK2|interpro:IPR032117|interpro:IPR035495|interpro:IPR035497|interpro:IPR035498|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|rgd:620191|refseq:NP_542421.2|interpro:IPR020683|interpro:IPR027013|interpro:IPR036028|interpro:IPR036770|interpro:IPR032232|mint:MINT-7034581(identity) refseq:NP_001269854.1|refseq:NP_001269855.1|refseq:NP_001269856.1|refseq:NP_005750.4|go:"GO:0005912"(adherens junction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007399"(nervous system development)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031209"(SCAR complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR035726|interpro:IPR036028|interpro:IPR036993|rcsb pdb:2ED0|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:XP_006712248.1|mint:Q9NYB9|dip:DIP-37566N|mint:MINT-7034582(identity) - function:May link the scaffolding protein CASK to downstream intracellular effectors|comment:mint - figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/05/07 2014/10/16 rogid:SV8ZmAh6nBzQOHc8+9ZpGaTMwqk10116 rogid:ceor35u+atlarKgbnb1tTQXcSZQ9606 intact-crc:57657B67A83AE63F|rigid:dGF/zFUtM01p1xLgx2XNfYvEZyU false binding-associated region:280-963(MINT-7034614)|tag:?-?(MINT-7034611) tag:?-?(MINT-7034607) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8VHK2 uniprotkb:P07498 intact:EBI-7049475|intact:MINT-238952 intact:EBI-2602175|uniprotkb:Q13575|ensembl:ENSP00000304822 psi-mi:cski1_rat(display_long)|uniprotkb:Caskin1(gene name)|psi-mi:Caskin1(display_short)|uniprotkb:CASK-interacting protein 1(gene name synonym) psi-mi:cask_human(display_long)|uniprotkb:CSN3(gene name)|psi-mi:CSN3(display_short)|uniprotkb:CASK(gene name synonym)|uniprotkb:CSN10(gene name synonym)|uniprotkb:CSNK(gene name synonym) psi-mi:"MI:0018"(two hybrid) Balázs et al. (2009) pubmed:19523119|mint:MINT-7034549|mint:fj-09-0215.r1 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7049566|mint:MINT-7034617 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q8VHK2|interpro:IPR032117|interpro:IPR035495|interpro:IPR035497|interpro:IPR035498|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|rgd:620191|refseq:NP_542421.2|interpro:IPR020683|interpro:IPR027013|interpro:IPR036028|interpro:IPR036770|interpro:IPR032232|mint:MINT-7034623(identity) refseq:XP_011529922.1|refseq:NP_005203.2|ensembl:ENSG00000171209(gene)|ensembl:ENST00000304954(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007595"(lactation)|go:"GO:0050821"(protein stabilization)|interpro:IPR000117(Kappa casein)|mint:P07498|reactome:R-HSA-5223345|refseq:XP_016863250.1|mint:MINT-7034619(identity) - function:May link the scaffolding protein CASK to downstream intracellular effectors|comment:mint - figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/05/07 2014/10/16 rogid:SV8ZmAh6nBzQOHc8+9ZpGaTMwqk10116 rogid:qmi1c3BKqV3ZBEVE8J7hTHJkvL09606 intact-crc:30C2DBE75EEF8A41|rigid:dbhDGqYtclZqmRiWqxfls0Ox4Vk false tag:?-?(MINT-7034626)|binding-associated region:280-963(MINT-7034624) tag:?-?(MINT-7034620) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8VHK2 uniprotkb:P29317 intact:EBI-7049475|intact:MINT-238952 intact:EBI-702104|uniprotkb:Q8N3Z2|uniprotkb:B5A968|intact:EBI-28989000|ensembl:ENSP00000351209 psi-mi:cski1_rat(display_long)|uniprotkb:Caskin1(gene name)|psi-mi:Caskin1(display_short)|uniprotkb:CASK-interacting protein 1(gene name synonym) psi-mi:epha2_human(display_long)|uniprotkb:Tyrosine-protein kinase receptor ECK(gene name synonym)|uniprotkb:Epithelial cell kinase(gene name synonym)|uniprotkb:EPHA2(gene name)|psi-mi:EPHA2(display_short)|uniprotkb:ECK(gene name synonym) psi-mi:"MI:0018"(two hybrid) Balázs et al. (2009) pubmed:19523119|mint:MINT-7034549|mint:fj-09-0215.r1 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7049616|mint:MINT-7034634 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q8VHK2|interpro:IPR032117|interpro:IPR035495|interpro:IPR035497|interpro:IPR035498|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|rgd:620191|refseq:NP_542421.2|interpro:IPR020683|interpro:IPR027013|interpro:IPR036028|interpro:IPR036770|interpro:IPR032232|mint:MINT-7034640(identity) refseq:NP_004422.2|ensembl:ENSP00000351209|dip:DIP-96N|ensembl:ENSG00000142627(gene)|ensembl:ENST00000358432(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002043"(blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007411"(axon guidance)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009986"(cell surface)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0014028"(notochord formation)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019838"(growth factor binding)|go:"GO:0021915"(neural tube development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043535"(regulation of blood vessel endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0046849"(bone remodeling)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048320"(axial mesoderm formation)|go:"GO:0048870"(cell motility)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060035"(notochord cell development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0070160"(tight junction)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1901491"(negative regulation of lymphangiogenesis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904238"(pericyte cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034263|interpro:IPR036116|mint:P29317|rcsb pdb:1MQB|rcsb pdb:2E8N|rcsb pdb:2K9Y|rcsb pdb:2KSO|rcsb pdb:2X10|rcsb pdb:2X11|rcsb pdb:3C8X|rcsb pdb:3CZU|rcsb pdb:3FL7|rcsb pdb:3HEI|rcsb pdb:3HPN|rcsb pdb:3KKA|rcsb pdb:3MBW|rcsb pdb:3MX0|rcsb pdb:3SKJ|rcsb pdb:4P2K|rcsb pdb:4PDO|rcsb pdb:4TRL|rcsb pdb:5EK7|rcsb pdb:5I9U|rcsb pdb:5I9V|rcsb pdb:5I9W|rcsb pdb:5I9X|rcsb pdb:5I9Y|rcsb pdb:5I9Z|rcsb pdb:5IA0|rcsb pdb:5IA1|rcsb pdb:5IA2|rcsb pdb:5IA3|rcsb pdb:5IA4|rcsb pdb:5IA5|rcsb pdb:5NJZ|rcsb pdb:5NK0|rcsb pdb:5NK1|rcsb pdb:5NK2|rcsb pdb:5NK3|rcsb pdb:5NK4|rcsb pdb:5NK5|rcsb pdb:5NK6|rcsb pdb:5NK7|rcsb pdb:5NK8|rcsb pdb:5NK9|rcsb pdb:5NKA|rcsb pdb:5NKB|rcsb pdb:5NKC|rcsb pdb:5NKD|rcsb pdb:5NKE|rcsb pdb:5NKF|rcsb pdb:5NKG|rcsb pdb:5NKH|rcsb pdb:5NKI|rcsb pdb:5NZ9|rcsb pdb:6B9L|rcsb pdb:6F7M|rcsb pdb:6F7N|rcsb pdb:6FNF|rcsb pdb:6FNG|rcsb pdb:6FNH|rcsb pdb:6HES|rcsb pdb:6HET|rcsb pdb:6HEU|rcsb pdb:6HEV|rcsb pdb:6HEW|rcsb pdb:6HEX|rcsb pdb:6HEY|rcsb pdb:6NJZ|rcsb pdb:6NK0|rcsb pdb:6NK1|rcsb pdb:6NK2|rcsb pdb:6NKP|rcsb pdb:6Q7B|rcsb pdb:6Q7C|rcsb pdb:6Q7D|rcsb pdb:6Q7E|rcsb pdb:6Q7F|rcsb pdb:6Q7G|rcsb pdb:6RW2|rcsb pdb:7B7N|rcsb pdb:7CZE|rcsb pdb:7CZF|rcsb pdb:7KJA|rcsb pdb:7KJB|rcsb pdb:7KJC|reactome:R-HSA-2682334|reactome:R-HSA-3928663|reactome:R-HSA-3928665|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|mint:MINT-7034636(identity) - function:May link the scaffolding protein CASK to downstream intracellular effectors|comment:mint - figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/05/07 2014/10/16 rogid:SV8ZmAh6nBzQOHc8+9ZpGaTMwqk10116 rogid:9VFikLd4ftRmEyBpY0JHdpHINT09606 intact-crc:BFAC53DE5E44F200|rigid:4j5HgGjFldG/PWOaP8I8DrCBo8M false binding-associated region:280-963(MINT-7034643)|tag:?-?(MINT-7034641) tag:?-?(MINT-7034637) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8VHK2 uniprotkb:P32004 intact:EBI-7049475|intact:MINT-238952 intact:EBI-720783|uniprotkb:B2RMU7|uniprotkb:A0AV65|uniprotkb:Q8TA87|uniprotkb:A4ZYW4|uniprotkb:G3XAF4|ensembl:ENSP00000359077 psi-mi:cski1_rat(display_long)|uniprotkb:Caskin1(gene name)|psi-mi:Caskin1(display_short)|uniprotkb:CASK-interacting protein 1(gene name synonym) psi-mi:l1cam_human(display_long)|uniprotkb:L1CAM(gene name)|psi-mi:L1CAM(display_short)|uniprotkb:CAML1(gene name synonym)|uniprotkb:MIC5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Balázs et al. (2009) pubmed:19523119|mint:MINT-7034549|mint:fj-09-0215.r1 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7049637|mint:MINT-7034649 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q8VHK2|interpro:IPR032117|interpro:IPR035495|interpro:IPR035497|interpro:IPR035498|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|rgd:620191|refseq:NP_542421.2|interpro:IPR020683|interpro:IPR027013|interpro:IPR036028|interpro:IPR036770|interpro:IPR032232|mint:MINT-7034655(identity) refseq:NP_000416.1|refseq:NP_001137435.1|refseq:NP_076493.1|refseq:NP_001265045.1|ensembl:ENSG00000198910(gene)|ensembl:ENST00000370060(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006935"(chemotaxis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0050808"(synapse organization)|go:"GO:0061564"(axon development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|mint:P32004|reactome:R-HSA-210991|reactome:R-HSA-373760|reactome:R-HSA-437239|reactome:R-HSA-445095|reactome:R-HSA-445144|mint:MINT-7034651(identity) - function:May link the scaffolding protein CASK to downstream intracellular effectors|comment:mint - figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/05/07 2014/10/16 rogid:SV8ZmAh6nBzQOHc8+9ZpGaTMwqk10116 rogid:ytWIAO1KRRtvqhmtH+CZjN/Hrbs9606 intact-crc:3A0C54BF7392071D|rigid:5VWKxJaf8ScHNL5soGk7+gm8RMM false tag:?-?(MINT-7034658)|binding-associated region:280-963(MINT-7034656) tag:?-?(MINT-7034652) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8VHK2 uniprotkb:P16333 intact:EBI-7049475|intact:MINT-238952 intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3 psi-mi:cski1_rat(display_long)|uniprotkb:Caskin1(gene name)|psi-mi:Caskin1(display_short)|uniprotkb:CASK-interacting protein 1(gene name synonym) psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym) psi-mi:"MI:0018"(two hybrid) Balázs et al. (2009) pubmed:19523119|mint:MINT-7034549|mint:fj-09-0215.r1 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7049679|mint:MINT-7034677 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q8VHK2|interpro:IPR032117|interpro:IPR035495|interpro:IPR035497|interpro:IPR035498|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|rgd:620191|refseq:NP_542421.2|interpro:IPR020683|interpro:IPR027013|interpro:IPR036028|interpro:IPR036770|interpro:IPR032232|mint:MINT-7034683(identity) refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|mint:MINT-7034679(identity) - function:May link the scaffolding protein CASK to downstream intracellular effectors|comment:mint - figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/05/07 2014/10/16 rogid:SV8ZmAh6nBzQOHc8+9ZpGaTMwqk10116 rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606 intact-crc:8A734564C1DC0A8C|rigid:vfGhyYt0/kfDvhNGMGNKe3Yntq4 false tag:?-?(MINT-7034686)|binding-associated region:280-963(MINT-7034684) tag:?-?(MINT-7034680) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8VHK2 uniprotkb:O43795 intact:EBI-7049475|intact:MINT-238952 intact:EBI-351119|uniprotkb:O43794|uniprotkb:Q7Z6L5|ensembl:ENSP00000306382|ensembl:ENSP00000376132 psi-mi:cski1_rat(display_long)|uniprotkb:Caskin1(gene name)|psi-mi:Caskin1(display_short)|uniprotkb:CASK-interacting protein 1(gene name synonym) psi-mi:myo1b_human(display_long)|uniprotkb:MYO1B(gene name)|psi-mi:MYO1B(display_short)|uniprotkb:Myosin I alpha(gene name synonym)|uniprotkb:MYH-1c(gene name synonym) psi-mi:"MI:0018"(two hybrid) Balázs et al. (2009) pubmed:19523119|mint:MINT-7034549|mint:fj-09-0215.r1 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7049658|mint:MINT-7034663 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q8VHK2|interpro:IPR032117|interpro:IPR035495|interpro:IPR035497|interpro:IPR035498|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|rgd:620191|refseq:NP_542421.2|interpro:IPR020683|interpro:IPR027013|interpro:IPR036028|interpro:IPR036770|interpro:IPR032232|mint:MINT-7034669(identity) refseq:NP_001123630.1|refseq:NP_001155291.1|refseq:NP_036355.2|ensembl:ENSG00000128641(gene)|ensembl:ENST00000304164(transcript)|ensembl:ENST00000392318(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030175"(filopodium)|go:"GO:0031982"(vesicle)|go:"GO:0045177"(apical part of cell)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:O43795|go:"GO:0016459"(myosin complex)|refseq:XP_005246629.1|mint:MINT-7034665(identity) - function:May link the scaffolding protein CASK to downstream intracellular effectors|comment:mint - figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/05/07 2014/10/16 rogid:SV8ZmAh6nBzQOHc8+9ZpGaTMwqk10116 rogid:FYYccaCMhkmUdTdtq4M8zdpFpV89606 intact-crc:0AFB5311691E1920|rigid:LZG6lWo1/DE99qTRNZtVNFxA2cA false tag:?-?(MINT-7034670)|binding-associated region:280-963(MINT-7034672) tag:?-?(MINT-7034666) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8VHK2 uniprotkb:P21579 intact:EBI-7049475|intact:MINT-238952 intact:EBI-524909|ensembl:ENSP00000261205|ensembl:ENSP00000376932|ensembl:ENSP00000447575|uniprotkb:Q6AI31 psi-mi:cski1_rat(display_long)|uniprotkb:Caskin1(gene name)|psi-mi:Caskin1(display_short)|uniprotkb:CASK-interacting protein 1(gene name synonym) psi-mi:syt1_human(display_long)|uniprotkb:Synaptotagmin I(gene name synonym)|uniprotkb:p65(gene name synonym)|uniprotkb:SYT1(gene name)|psi-mi:SYT1(display_short)|uniprotkb:SYT(gene name synonym)|uniprotkb:SVP65(gene name synonym) psi-mi:"MI:0018"(two hybrid) Balázs et al. (2009) pubmed:19523119|mint:MINT-7034549|mint:fj-09-0215.r1 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7049757|mint:MINT-7034720 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q8VHK2|interpro:IPR032117|interpro:IPR035495|interpro:IPR035497|interpro:IPR035498|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|rgd:620191|refseq:NP_542421.2|interpro:IPR020683|interpro:IPR027013|interpro:IPR036028|interpro:IPR036770|interpro:IPR032232|mint:MINT-7034726(identity) refseq:NP_001129277.1|refseq:NP_001129278.1|refseq:NP_005630.1|ensembl:ENSG00000067715(gene)|ensembl:ENST00000261205(transcript)|ensembl:ENST00000393240(transcript)|ensembl:ENST00000552744(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|refseq:XP_011537012.1|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030276"(clathrin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030348"(syntaxin-3 binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0030424"(axon)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031045"(dense core granule)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0042584"(chromaffin granule membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048278"(vesicle docking)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060201"(clathrin-sculpted acetylcholine transport vesicle membrane)|go:"GO:0060203"(clathrin-sculpted glutamate transport vesicle membrane)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0061891"(calcium ion sensor activity)|go:"GO:0070083"(clathrin-sculpted monoamine transport vesicle membrane)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071911"(synchronous neurotransmitter secretion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098746"(fast, calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099502"(calcium-dependent activation of synaptic vesicle fusion)|go:"GO:1903235"(positive regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR015428(Synaptotagmin 1,2)|interpro:IPR035892|mint:P21579|rcsb pdb:2K45|rcsb pdb:2K4A|rcsb pdb:2K8M|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|rcsb pdb:2LHA|rcsb pdb:2N1T|rcsb pdb:2KI6|rcsb pdb:2R83|rcsb pdb:3F00|rcsb pdb:3F01|rcsb pdb:3F04|rcsb pdb:3F05|rcsb pdb:4ISQ|rcsb pdb:4V11|rcsb pdb:6G5F|rcsb pdb:6G5K|rcsb pdb:6QNS|rcsb pdb:6TZ3|rcsb pdb:6U41|rcsb pdb:6U4U|rcsb pdb:6U4W|rcsb pdb:6ZVN|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-5250958|reactome:R-HSA-5250989|reactome:R-HSA-6794361|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-888590|reactome:R-HSA-210500|refseq:XP_016875398.1|dip:DIP-34042N|mint:MINT-7034722(identity) - function:May link the scaffolding protein CASK to downstream intracellular effectors|comment:mint - figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/05/07 2014/10/16 rogid:SV8ZmAh6nBzQOHc8+9ZpGaTMwqk10116 rogid:oWQJLjUokM2dCvvO+VHVbHUj/WE9606 intact-crc:58018AE47657C9A5|rigid:NpQ+r/Y/xkD5j2goWh5lSMj9H8w false binding-associated region:280-963(MINT-7034729)|tag:?-?(MINT-7034727) tag:?-?(MINT-7034723) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8VHK2 uniprotkb:Q9NZ72 intact:EBI-7049475|intact:MINT-238952 intact:EBI-725557|uniprotkb:O75527|uniprotkb:Q969Y4|uniprotkb:B7WP52|uniprotkb:B3KSQ5|uniprotkb:B7Z5G4|ensembl:ENSP00000359070 psi-mi:cski1_rat(display_long)|uniprotkb:Caskin1(gene name)|psi-mi:Caskin1(display_short)|uniprotkb:CASK-interacting protein 1(gene name synonym) psi-mi:stmn3_human(display_long)|uniprotkb:SCG10-like protein(gene name synonym)|uniprotkb:STMN3(gene name)|psi-mi:STMN3(display_short)|uniprotkb:SCLIP(gene name synonym) psi-mi:"MI:0018"(two hybrid) Balázs et al. (2009) pubmed:19523119|mint:MINT-7034549|mint:fj-09-0215.r1 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7049736|mint:MINT-7034706 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q8VHK2|interpro:IPR032117|interpro:IPR035495|interpro:IPR035497|interpro:IPR035498|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|rgd:620191|refseq:NP_542421.2|interpro:IPR020683|interpro:IPR027013|interpro:IPR036028|interpro:IPR036770|interpro:IPR032232|mint:MINT-7034712(identity) refseq:NP_056978.2|refseq:NP_001263239.1|ensembl:ENSG00000197457(gene)|ensembl:ENST00000370053(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007399"(nervous system development)|go:"GO:0015631"(tubulin binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030426"(growth cone)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0035021"(negative regulation of Rac protein signal transduction)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|interpro:IPR000956(Stathmin)|interpro:IPR028835|interpro:IPR030514|interpro:IPR036002|mint:Q9NZ72|mint:MINT-7034708(identity) - function:May link the scaffolding protein CASK to downstream intracellular effectors|comment:mint - figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/05/07 2014/10/16 rogid:SV8ZmAh6nBzQOHc8+9ZpGaTMwqk10116 rogid:JIKhugedhdetNr3tVCP0PSVd7YA9606 intact-crc:B12A0BE3C11F1822|rigid:KbjKwPZJGV1GoZ+xMTj9P63ZvB0 false binding-associated region:280-963(MINT-7034713)|tag:?-?(MINT-7034715) tag:?-?(MINT-7034709) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8VHK2 uniprotkb:Q9P2S2 intact:EBI-7049475|intact:MINT-238952 intact:EBI-310939|uniprotkb:Q9Y2D6|uniprotkb:A7E2C1|ensembl:ENSP00000265459 psi-mi:cski1_rat(display_long)|uniprotkb:Caskin1(gene name)|psi-mi:Caskin1(display_short)|uniprotkb:CASK-interacting protein 1(gene name synonym) psi-mi:nrx2a_human(display_long)|uniprotkb:NRXN2(gene name)|psi-mi:NRXN2(display_short)|uniprotkb:KIAA0921(gene name synonym)|uniprotkb:Neurexin II-alpha(gene name synonym)|uniprotkb:Neurexin-2-alpha(gene name synonym) psi-mi:"MI:0018"(two hybrid) Balázs et al. (2009) pubmed:19523119|mint:MINT-7034549|mint:fj-09-0215.r1 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7049715|mint:MINT-7034691 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q8VHK2|interpro:IPR032117|interpro:IPR035495|interpro:IPR035497|interpro:IPR035498|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|rgd:620191|refseq:NP_542421.2|interpro:IPR020683|interpro:IPR027013|interpro:IPR036028|interpro:IPR036770|interpro:IPR032232|mint:MINT-7034697(identity) ensembl:ENSG00000110076(gene)|ensembl:ENST00000265459(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|refseq:NP_055895.1|refseq:NP_620060.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0030534"(adult behavior)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035176"(social behavior)|go:"GO:0042297"(vocal learning)|go:"GO:0046872"(metal ion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097116"(gephyrin clustering involved in postsynaptic density assembly)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097119"(postsynaptic density protein 95 clustering)|go:"GO:0098793"(presynapse)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|mint:Q9P2S2|reactome:R-HSA-6794361|mint:MINT-7034693(identity) - function:May link the scaffolding protein CASK to downstream intracellular effectors|comment:mint - figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/05/07 2014/10/16 rogid:SV8ZmAh6nBzQOHc8+9ZpGaTMwqk10116 rogid:x48PiRJgHC6O0Fj6PgkY7FNW3Jc9606 intact-crc:59DAE302D887D2E0|rigid:58TgppXKeLw+S/XATmAPusT4/xA false binding-associated region:280-963(MINT-7034700)|tag:?-?(MINT-7034698) tag:?-?(MINT-7034694) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8VHK2 uniprotkb:Q8IUQ4 intact:EBI-7049475|intact:MINT-238952 intact:EBI-747107|uniprotkb:O43269|uniprotkb:Q49A58|uniprotkb:A0FKF3|uniprotkb:Q92880|ensembl:ENSP00000369343|ensembl:ENSP00000378214|ensembl:ENSP00000456421 psi-mi:cski1_rat(display_long)|uniprotkb:Caskin1(gene name)|psi-mi:Caskin1(display_short)|uniprotkb:CASK-interacting protein 1(gene name synonym) psi-mi:siah1_human(display_long)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Balázs et al. (2009) pubmed:19523119|mint:MINT-7034549|mint:fj-09-0215.r1 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7049799|mint:MINT-7034748 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q8VHK2|interpro:IPR032117|interpro:IPR035495|interpro:IPR035497|interpro:IPR035498|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|rgd:620191|refseq:NP_542421.2|interpro:IPR020683|interpro:IPR027013|interpro:IPR036028|interpro:IPR036770|interpro:IPR032232|mint:MINT-7034754(identity) refseq:XP_006721309.1|refseq:NP_001006611.1|refseq:NP_003022.3|refseq:XP_011521581.1|ensembl:ENST00000380006(transcript)|ensembl:ENST00000394725(transcript)|ensembl:ENST00000568007(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|mint:Q8IUQ4|rcsb pdb:2A25|rcsb pdb:4C9Z|rcsb pdb:4CA1|rcsb pdb:4I7B|rcsb pdb:4I7C|rcsb pdb:4I7D|rcsb pdb:4X3G|rcsb pdb:5WZZ|reactome:R-HSA-373752|reactome:R-HSA-977225|reactome:R-HSA-983168|ensembl:ENSG00000196470(gene)|dip:DIP-35684N|mint:MINT-7034750(identity) - function:May link the scaffolding protein CASK to downstream intracellular effectors|comment:mint - figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/05/07 2014/10/16 rogid:SV8ZmAh6nBzQOHc8+9ZpGaTMwqk10116 rogid:O6+z1g9K1ij87Xgo5/Ykl5Q3vUQ9606 intact-crc:D169CA4823DAED5F|rigid:y+ymgkzrztIgE2C6HRznRNG1pko false binding-associated region:280-963(MINT-7034757)|tag:?-?(MINT-7034755) tag:?-?(MINT-7034751) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8VHK2 uniprotkb:O43236 intact:EBI-7049475|intact:MINT-238952 intact:EBI-1047513|uniprotkb:Q9UM58|uniprotkb:Q6IAP3|uniprotkb:B2RD42|uniprotkb:B3KSX9|uniprotkb:B4DXC6|uniprotkb:B4DXV5|uniprotkb:Q9H315|ensembl:ENSP00000321674|uniprotkb:A0A5F9ZHH3|uniprotkb:Q8N821|uniprotkb:Q8NEP4|intact:EBI-25939820|intact:EBI-13336111 psi-mi:cski1_rat(display_long)|uniprotkb:Caskin1(gene name)|psi-mi:Caskin1(display_short)|uniprotkb:CASK-interacting protein 1(gene name synonym) psi-mi:sept4_human(display_long)|uniprotkb:SEPTIN4(gene name)|psi-mi:SEPTIN4(display_short)|uniprotkb:ARTS(gene name synonym)|uniprotkb:Apoptosis-related protein in the TGF-beta signaling pathway(gene name synonym)|uniprotkb:Bradeion beta(gene name synonym)|uniprotkb:Brain protein H5(gene name synonym)|uniprotkb:CE5B3 beta(gene name synonym)|uniprotkb:Cell division control-related protein 2(gene name synonym)|uniprotkb:Cerebral protein 7(gene name synonym)|uniprotkb:PNUTL2(gene name synonym)|uniprotkb:Peanut-like protein 2(gene name synonym)|uniprotkb:SEP4(gene name synonym)|uniprotkb:SEPT4(gene name synonym)|uniprotkb:hucep-7(orf name)|uniprotkb:C17orf47(gene name synonym) psi-mi:"MI:0018"(two hybrid) Balázs et al. (2009) pubmed:19523119|mint:MINT-7034549|mint:fj-09-0215.r1 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7049778|mint:MINT-7034734 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q8VHK2|interpro:IPR032117|interpro:IPR035495|interpro:IPR035497|interpro:IPR035498|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|rgd:620191|refseq:NP_542421.2|interpro:IPR020683|interpro:IPR027013|interpro:IPR036028|interpro:IPR036770|interpro:IPR032232|mint:MINT-7034740(identity) refseq:XP_011523213.1|refseq:XP_011523214.1|refseq:NP_001185642.1|refseq:NP_004565.1|refseq:NP_536341.1|refseq:NP_536340.1|refseq:NP_001033793.2|refseq:NP_001243711.1|refseq:NP_001243751.1|ensembl:ENSG00000108387(gene)|interpro:IPR027417|interpro:IPR030379|mint:O43236|rcsb pdb:6WB3|reactome:R-HSA-111457|reactome:R-HSA-111469|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|ensembl:ENST00000317268(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0001764"(neuron migration)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0003924"(GTPase activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0005198"(structural molecule activity)|go:"GO:0031105"(septin complex)|go:"GO:0005525"(GTP binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR016491(Septin)|refseq:XP_006722017.1|refseq:XP_006722018.1|mint:MINT-7034736(identity) - function:May link the scaffolding protein CASK to downstream intracellular effectors|comment:mint - figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/05/07 2014/10/16 rogid:SV8ZmAh6nBzQOHc8+9ZpGaTMwqk10116 rogid:bS5LZDK5bxr0WEZsE35enupzNQs9606 intact-crc:C5FEE82842455A3E|rigid:PJiSkTNLTEl61drUrQMVG3PcWyk false tag:?-?(MINT-7034743)|binding-associated region:280-963(MINT-7034741) tag:?-?(MINT-7034737) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8VHK2 uniprotkb:Q9NYB9 intact:EBI-7049475|intact:MINT-238952 intact:EBI-743598|uniprotkb:Q13147|uniprotkb:Q13249|uniprotkb:Q13801|uniprotkb:Q9BV70|uniprotkb:B4DSN1 psi-mi:cski1_rat(display_long)|uniprotkb:Caskin1(gene name)|psi-mi:Caskin1(display_short)|uniprotkb:CASK-interacting protein 1(gene name synonym) psi-mi:abi2_human(display_long)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym) psi-mi:"MI:0096"(pull down) Balázs et al. (2009) pubmed:19523119|mint:MINT-7034549|mint:fj-09-0215.r1 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7049842|mint:MINT-7034765 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q8VHK2|interpro:IPR032117|interpro:IPR035495|interpro:IPR035497|interpro:IPR035498|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|rgd:620191|refseq:NP_542421.2|interpro:IPR020683|interpro:IPR027013|interpro:IPR036028|interpro:IPR036770|interpro:IPR032232|mint:MINT-7034771(identity) refseq:NP_001269854.1|refseq:NP_001269855.1|refseq:NP_001269856.1|refseq:NP_005750.4|go:"GO:0005912"(adherens junction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007399"(nervous system development)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031209"(SCAR complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR035726|interpro:IPR036028|interpro:IPR036993|rcsb pdb:2ED0|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:XP_006712248.1|mint:Q9NYB9|dip:DIP-37566N|mint:MINT-7034767(identity) - function:May link the scaffolding protein CASK to downstream intracellular effectors|comment:mint - figure legend:F5|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/07 2014/10/16 rogid:SV8ZmAh6nBzQOHc8+9ZpGaTMwqk10116 rogid:ceor35u+atlarKgbnb1tTQXcSZQ9606 intact-crc:4C64BA408D0A8C47|rigid:dGF/zFUtM01p1xLgx2XNfYvEZyU false glutathione s tranferase tag:?-?(MINT-7034774)|binding-associated region:603-804(MINT-7034772) green fluorescent protein tag:?-?(MINT-7034768) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8VHK2 uniprotkb:Q9NYB9 intact:EBI-7049475|intact:MINT-238952 intact:EBI-743598|uniprotkb:Q13147|uniprotkb:Q13249|uniprotkb:Q13801|uniprotkb:Q9BV70|uniprotkb:B4DSN1 psi-mi:cski1_rat(display_long)|uniprotkb:Caskin1(gene name)|psi-mi:Caskin1(display_short)|uniprotkb:CASK-interacting protein 1(gene name synonym) psi-mi:abi2_human(display_long)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym) psi-mi:"MI:0096"(pull down) Balázs et al. (2009) pubmed:19523119|mint:MINT-7034549|mint:fj-09-0215.r1 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7049864|mint:MINT-7034783 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q8VHK2|interpro:IPR032117|interpro:IPR035495|interpro:IPR035497|interpro:IPR035498|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|rgd:620191|refseq:NP_542421.2|interpro:IPR020683|interpro:IPR027013|interpro:IPR036028|interpro:IPR036770|interpro:IPR032232|mint:MINT-7034789(identity) refseq:NP_001269854.1|refseq:NP_001269855.1|refseq:NP_001269856.1|refseq:NP_005750.4|go:"GO:0005912"(adherens junction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007399"(nervous system development)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031209"(SCAR complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR035726|interpro:IPR036028|interpro:IPR036993|rcsb pdb:2ED0|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:XP_006712248.1|mint:Q9NYB9|dip:DIP-37566N|mint:MINT-7034785(identity) - function:May link the scaffolding protein CASK to downstream intracellular effectors|comment:mint - figure legend:F5|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/07 2014/10/16 rogid:SV8ZmAh6nBzQOHc8+9ZpGaTMwqk10116 rogid:ceor35u+atlarKgbnb1tTQXcSZQ9606 intact-crc:98725A4440E99202|rigid:dGF/zFUtM01p1xLgx2XNfYvEZyU false binding-associated region:804-1199(MINT-7034792)|glutathione s tranferase tag:?-?(MINT-7034790) green fluorescent protein tag:?-?(MINT-7034786) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot)