#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P15382	uniprotkb:P51787	intact:EBI-7043557|ensembl:ENSP00000337255|ensembl:ENSP00000382225|ensembl:ENSP00000382226|ensembl:ENSP00000382228|ensembl:ENSP00000412498|ensembl:ENSP00000416258|ensembl:ENSP00000478215|ensembl:ENSP00000483895|uniprotkb:Q91Z94|intact:MINT-7297782|uniprotkb:Q8N709|uniprotkb:A5H1P2	intact:EBI-359667|intact:EBI-1760548|uniprotkb:O00347|uniprotkb:O60607|uniprotkb:O94787|uniprotkb:Q7Z6G9|uniprotkb:Q92960|uniprotkb:Q9UMN8|uniprotkb:Q9UMN9|uniprotkb:Q14D14|intact:EBI-1965607|ensembl:ENSP00000155840	psi-mi:kcne1_human(display_long)|uniprotkb:KCNE1(gene name)|psi-mi:KCNE1(display_short)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit beta Mink(gene name synonym)|uniprotkb:Minimal potassium channel(gene name synonym)|uniprotkb:Delayed rectifier potassium channel subunit IsK(gene name synonym)	psi-mi:kcnq1_human(display_long)|uniprotkb:KCNQ1(gene name)|psi-mi:KCNQ1(display_short)|uniprotkb:KCNA8(gene name synonym)|uniprotkb:KCNA9(gene name synonym)|uniprotkb:KVLQT1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Haitin et al. (2009)	pubmed:19521339|imex:IM-14118|mint:MINT-7297773|doi:10.1038/emboj.2009.157	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0471"(MINT)	intact:EBI-7043550|mint:MINT-7297812|imex:IM-14118-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000180509(gene)|ensembl:ENST00000337385(transcript)|ensembl:ENST00000399284(transcript)|ensembl:ENST00000399286(transcript)|ensembl:ENST00000399289(transcript)|ensembl:ENST00000416357(transcript)|ensembl:ENST00000432085(transcript)|ensembl:ENST00000611936(transcript)|ensembl:ENST00000621601(transcript)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005764"(lysosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0031433"(telethonin binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902259"(regulation of delayed rectifier potassium channel activity)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000369(Potassium channel, voltage-dependent, beta subunit, KCNE)|interpro:IPR005424(Potassium channel, voltage-dependent, beta subunit, KCNE1)|mint:P15382|rcsb pdb:2K21|reactome:R-HSA-5576890|reactome:R-HSA-5576893|refseq:NP_001121141.1|refseq:NP_001121140.1|refseq:NP_000210.2|refseq:NP_001257334.1|refseq:NP_001257331.1|refseq:NP_001257333.1|refseq:NP_001257332.1|refseq:NP_001121142.1|mint:MINT-7297815(identity)	refseq:NP_000209.2|refseq:NP_861463.1|ensembl:ENSG00000053918(gene)|ensembl:ENST00000155840(transcript)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|mint:P51787|rcsb pdb:3BJ4|rcsb pdb:3HFC|rcsb pdb:3HFE|rcsb pdb:4UMO|rcsb pdb:4V0C|rcsb pdb:6MIE|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|reactome:R-HSA-1296072|reactome:R-HSA-5576890|reactome:R-HSA-5576893|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|dip:DIP-27591N|dip:DIP-29941N|mint:MINT-7297814(identity)	-	comment:mint	caution:This sequence has been withdrawn from Uniprot.|crc64:ADFCA9E2B9763B21	comment:homomint|comment:mint|figure legend:f2 f6a f6b f6e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis)	-	2009/11/09	2014/10/16	rogid:y68EBvBKDIRCu+MDWcaRVBtBoH09606	rogid:w5Bp2fzyW56IIPAgVjXWgOOAlr49606	intact-crc:296EFD9C14CC6DD9|rigid:bNLoy9JS/Jbpq49Dpym9FP5qRLQ	false	yellow fluorescent protein tag:?-?(MINT-7297820)|mutation increasing interaction:76-76(MINT-7297850)	cyan fluorescent protein tag:?-?(MINT-7297825)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P15382	uniprotkb:P51787	intact:EBI-7043557|ensembl:ENSP00000337255|ensembl:ENSP00000382225|ensembl:ENSP00000382226|ensembl:ENSP00000382228|ensembl:ENSP00000412498|ensembl:ENSP00000416258|ensembl:ENSP00000478215|ensembl:ENSP00000483895|uniprotkb:Q91Z94|intact:MINT-7297782|uniprotkb:Q8N709|uniprotkb:A5H1P2	intact:EBI-359667|intact:EBI-1760548|uniprotkb:O00347|uniprotkb:O60607|uniprotkb:O94787|uniprotkb:Q7Z6G9|uniprotkb:Q92960|uniprotkb:Q9UMN8|uniprotkb:Q9UMN9|uniprotkb:Q14D14|intact:EBI-1965607|ensembl:ENSP00000155840	psi-mi:kcne1_human(display_long)|uniprotkb:KCNE1(gene name)|psi-mi:KCNE1(display_short)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit beta Mink(gene name synonym)|uniprotkb:Minimal potassium channel(gene name synonym)|uniprotkb:Delayed rectifier potassium channel subunit IsK(gene name synonym)	psi-mi:kcnq1_human(display_long)|uniprotkb:KCNQ1(gene name)|psi-mi:KCNQ1(display_short)|uniprotkb:KCNA8(gene name synonym)|uniprotkb:KCNA9(gene name synonym)|uniprotkb:KVLQT1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Haitin et al. (2009)	pubmed:19521339|imex:IM-14118|mint:MINT-7297773|doi:10.1038/emboj.2009.157	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0471"(MINT)	intact:EBI-7043616|mint:MINT-7297906|imex:IM-14118-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000180509(gene)|ensembl:ENST00000337385(transcript)|ensembl:ENST00000399284(transcript)|ensembl:ENST00000399286(transcript)|ensembl:ENST00000399289(transcript)|ensembl:ENST00000416357(transcript)|ensembl:ENST00000432085(transcript)|ensembl:ENST00000611936(transcript)|ensembl:ENST00000621601(transcript)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005764"(lysosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0031433"(telethonin binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902259"(regulation of delayed rectifier potassium channel activity)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000369(Potassium channel, voltage-dependent, beta subunit, KCNE)|interpro:IPR005424(Potassium channel, voltage-dependent, beta subunit, KCNE1)|mint:P15382|rcsb pdb:2K21|reactome:R-HSA-5576890|reactome:R-HSA-5576893|refseq:NP_001121141.1|refseq:NP_001121140.1|refseq:NP_000210.2|refseq:NP_001257334.1|refseq:NP_001257331.1|refseq:NP_001257333.1|refseq:NP_001257332.1|refseq:NP_001121142.1|mint:MINT-7297908(identity)	refseq:NP_000209.2|refseq:NP_861463.1|ensembl:ENSG00000053918(gene)|ensembl:ENST00000155840(transcript)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|mint:P51787|rcsb pdb:3BJ4|rcsb pdb:3HFC|rcsb pdb:3HFE|rcsb pdb:4UMO|rcsb pdb:4V0C|rcsb pdb:6MIE|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|reactome:R-HSA-1296072|reactome:R-HSA-5576890|reactome:R-HSA-5576893|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|dip:DIP-27591N|dip:DIP-29941N|mint:MINT-7297914(identity)	-	comment:mint	caution:This sequence has been withdrawn from Uniprot.|crc64:ADFCA9E2B9763B21	comment:homomint|comment:mint|figure legend:f7b f7d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis)	-	2009/11/09	2014/10/16	rogid:y68EBvBKDIRCu+MDWcaRVBtBoH09606	rogid:w5Bp2fzyW56IIPAgVjXWgOOAlr49606	intact-crc:155CE723E037AF43|rigid:bNLoy9JS/Jbpq49Dpym9FP5qRLQ	false	cyan fluorescent protein tag:?-?(MINT-7297911)	yellow fluorescent protein tag:?-?(MINT-7297915)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P15382	uniprotkb:P51787	intact:EBI-7043557|ensembl:ENSP00000337255|ensembl:ENSP00000382225|ensembl:ENSP00000382226|ensembl:ENSP00000382228|ensembl:ENSP00000412498|ensembl:ENSP00000416258|ensembl:ENSP00000478215|ensembl:ENSP00000483895|uniprotkb:Q91Z94|intact:MINT-7297782|uniprotkb:Q8N709|uniprotkb:A5H1P2	intact:EBI-359667|intact:EBI-1760548|uniprotkb:O00347|uniprotkb:O60607|uniprotkb:O94787|uniprotkb:Q7Z6G9|uniprotkb:Q92960|uniprotkb:Q9UMN8|uniprotkb:Q9UMN9|uniprotkb:Q14D14|intact:EBI-1965607|ensembl:ENSP00000155840	psi-mi:kcne1_human(display_long)|uniprotkb:KCNE1(gene name)|psi-mi:KCNE1(display_short)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit beta Mink(gene name synonym)|uniprotkb:Minimal potassium channel(gene name synonym)|uniprotkb:Delayed rectifier potassium channel subunit IsK(gene name synonym)	psi-mi:kcnq1_human(display_long)|uniprotkb:KCNQ1(gene name)|psi-mi:KCNQ1(display_short)|uniprotkb:KCNA8(gene name synonym)|uniprotkb:KCNA9(gene name synonym)|uniprotkb:KVLQT1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Haitin et al. (2009)	pubmed:19521339|imex:IM-14118|mint:MINT-7297773|doi:10.1038/emboj.2009.157	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7043659|mint:MINT-7297829|imex:IM-14118-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000180509(gene)|ensembl:ENST00000337385(transcript)|ensembl:ENST00000399284(transcript)|ensembl:ENST00000399286(transcript)|ensembl:ENST00000399289(transcript)|ensembl:ENST00000416357(transcript)|ensembl:ENST00000432085(transcript)|ensembl:ENST00000611936(transcript)|ensembl:ENST00000621601(transcript)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005764"(lysosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0031433"(telethonin binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902259"(regulation of delayed rectifier potassium channel activity)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000369(Potassium channel, voltage-dependent, beta subunit, KCNE)|interpro:IPR005424(Potassium channel, voltage-dependent, beta subunit, KCNE1)|mint:P15382|rcsb pdb:2K21|reactome:R-HSA-5576890|reactome:R-HSA-5576893|refseq:NP_001121141.1|refseq:NP_001121140.1|refseq:NP_000210.2|refseq:NP_001257334.1|refseq:NP_001257331.1|refseq:NP_001257333.1|refseq:NP_001257332.1|refseq:NP_001121142.1|mint:MINT-7297831(identity)	refseq:NP_000209.2|refseq:NP_861463.1|ensembl:ENSG00000053918(gene)|ensembl:ENST00000155840(transcript)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|mint:P51787|rcsb pdb:3BJ4|rcsb pdb:3HFC|rcsb pdb:3HFE|rcsb pdb:4UMO|rcsb pdb:4V0C|rcsb pdb:6MIE|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|reactome:R-HSA-1296072|reactome:R-HSA-5576890|reactome:R-HSA-5576893|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|dip:DIP-27591N|dip:DIP-29941N|mint:MINT-7297835(identity)	-	comment:mint	caution:This sequence has been withdrawn from Uniprot.|crc64:ADFCA9E2B9763B21	figure legend:f4b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2009/11/09	2014/10/16	rogid:y68EBvBKDIRCu+MDWcaRVBtBoH09606	rogid:w5Bp2fzyW56IIPAgVjXWgOOAlr49606	intact-crc:83B13F8CAF760A2D|rigid:bNLoy9JS/Jbpq49Dpym9FP5qRLQ	false	-	flag tag:?-?(MINT-7297836)|binding-associated region:510-620(MINT-7297847)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P15382	uniprotkb:P51787	intact:EBI-7043557|ensembl:ENSP00000337255|ensembl:ENSP00000382225|ensembl:ENSP00000382226|ensembl:ENSP00000382228|ensembl:ENSP00000412498|ensembl:ENSP00000416258|ensembl:ENSP00000478215|ensembl:ENSP00000483895|uniprotkb:Q91Z94|intact:MINT-7297782|uniprotkb:Q8N709|uniprotkb:A5H1P2	intact:EBI-359667|intact:EBI-1760548|uniprotkb:O00347|uniprotkb:O60607|uniprotkb:O94787|uniprotkb:Q7Z6G9|uniprotkb:Q92960|uniprotkb:Q9UMN8|uniprotkb:Q9UMN9|uniprotkb:Q14D14|intact:EBI-1965607|ensembl:ENSP00000155840	psi-mi:kcne1_human(display_long)|uniprotkb:KCNE1(gene name)|psi-mi:KCNE1(display_short)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit beta Mink(gene name synonym)|uniprotkb:Minimal potassium channel(gene name synonym)|uniprotkb:Delayed rectifier potassium channel subunit IsK(gene name synonym)	psi-mi:kcnq1_human(display_long)|uniprotkb:KCNQ1(gene name)|psi-mi:KCNQ1(display_short)|uniprotkb:KCNA8(gene name synonym)|uniprotkb:KCNA9(gene name synonym)|uniprotkb:KVLQT1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Haitin et al. (2009)	pubmed:19521339|imex:IM-14118|mint:MINT-7297773|doi:10.1038/emboj.2009.157	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7043702|mint:MINT-7297854|imex:IM-14118-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000180509(gene)|ensembl:ENST00000337385(transcript)|ensembl:ENST00000399284(transcript)|ensembl:ENST00000399286(transcript)|ensembl:ENST00000399289(transcript)|ensembl:ENST00000416357(transcript)|ensembl:ENST00000432085(transcript)|ensembl:ENST00000611936(transcript)|ensembl:ENST00000621601(transcript)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005764"(lysosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0031433"(telethonin binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902259"(regulation of delayed rectifier potassium channel activity)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000369(Potassium channel, voltage-dependent, beta subunit, KCNE)|interpro:IPR005424(Potassium channel, voltage-dependent, beta subunit, KCNE1)|mint:P15382|rcsb pdb:2K21|reactome:R-HSA-5576890|reactome:R-HSA-5576893|refseq:NP_001121141.1|refseq:NP_001121140.1|refseq:NP_000210.2|refseq:NP_001257334.1|refseq:NP_001257331.1|refseq:NP_001257333.1|refseq:NP_001257332.1|refseq:NP_001121142.1|mint:MINT-7297862(identity)	refseq:NP_000209.2|refseq:NP_861463.1|ensembl:ENSG00000053918(gene)|ensembl:ENST00000155840(transcript)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|mint:P51787|rcsb pdb:3BJ4|rcsb pdb:3HFC|rcsb pdb:3HFE|rcsb pdb:4UMO|rcsb pdb:4V0C|rcsb pdb:6MIE|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|reactome:R-HSA-1296072|reactome:R-HSA-5576890|reactome:R-HSA-5576893|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|dip:DIP-27591N|dip:DIP-29941N|mint:MINT-7297856(identity)	-	comment:mint	caution:This sequence has been withdrawn from Uniprot.|crc64:ADFCA9E2B9763B21	comment:homomint|comment:mint|figure legend:f5b f5d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/11/09	2014/10/16	rogid:y68EBvBKDIRCu+MDWcaRVBtBoH09606	rogid:w5Bp2fzyW56IIPAgVjXWgOOAlr49606	intact-crc:6C691FCFC5D0DE70|rigid:bNLoy9JS/Jbpq49Dpym9FP5qRLQ	false	binding-associated region:109-129(MINT-7297873)|glutathione s tranferase tag:?-?(MINT-7297871)	his tag:?-?(MINT-7297859)|binding-associated region:352-622(MINT-7297857)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P62158	uniprotkb:P15382	intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23	intact:EBI-7043557|ensembl:ENSP00000337255|ensembl:ENSP00000382225|ensembl:ENSP00000382226|ensembl:ENSP00000382228|ensembl:ENSP00000412498|ensembl:ENSP00000416258|ensembl:ENSP00000478215|ensembl:ENSP00000483895|uniprotkb:Q91Z94|intact:MINT-7297782|uniprotkb:Q8N709|uniprotkb:A5H1P2	psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym)	psi-mi:kcne1_human(display_long)|uniprotkb:KCNE1(gene name)|psi-mi:KCNE1(display_short)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit beta Mink(gene name synonym)|uniprotkb:Minimal potassium channel(gene name synonym)|uniprotkb:Delayed rectifier potassium channel subunit IsK(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Haitin et al. (2009)	pubmed:19521339|imex:IM-14118|mint:MINT-7297773|doi:10.1038/emboj.2009.157	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7043736|mint:MINT-7297878|imex:IM-14118-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O|mint:MINT-7297901(identity)	ensembl:ENSG00000180509(gene)|ensembl:ENST00000337385(transcript)|ensembl:ENST00000399284(transcript)|ensembl:ENST00000399286(transcript)|ensembl:ENST00000399289(transcript)|ensembl:ENST00000416357(transcript)|ensembl:ENST00000432085(transcript)|ensembl:ENST00000611936(transcript)|ensembl:ENST00000621601(transcript)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005764"(lysosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0031433"(telethonin binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902259"(regulation of delayed rectifier potassium channel activity)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000369(Potassium channel, voltage-dependent, beta subunit, KCNE)|interpro:IPR005424(Potassium channel, voltage-dependent, beta subunit, KCNE1)|mint:P15382|rcsb pdb:2K21|reactome:R-HSA-5576890|reactome:R-HSA-5576893|refseq:NP_001121141.1|refseq:NP_001121140.1|refseq:NP_000210.2|refseq:NP_001257334.1|refseq:NP_001257331.1|refseq:NP_001257333.1|refseq:NP_001257332.1|refseq:NP_001121142.1|mint:MINT-7297880(identity)	-	-	comment:mint	figure legend:f5a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/11/09	2014/10/16	rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606	rogid:y68EBvBKDIRCu+MDWcaRVBtBoH09606	intact-crc:11AE0182C64F71CC|rigid:oyRJG+tP+dGZBp2xCoQSBlVqP9M	false	-	binding-associated region:67-129(MINT-7297881)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P62158	uniprotkb:P51787	intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23	intact:EBI-359667|intact:EBI-1760548|uniprotkb:O00347|uniprotkb:O60607|uniprotkb:O94787|uniprotkb:Q7Z6G9|uniprotkb:Q92960|uniprotkb:Q9UMN8|uniprotkb:Q9UMN9|uniprotkb:Q14D14|intact:EBI-1965607|ensembl:ENSP00000155840	psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym)	psi-mi:kcnq1_human(display_long)|uniprotkb:KCNQ1(gene name)|psi-mi:KCNQ1(display_short)|uniprotkb:KCNA8(gene name synonym)|uniprotkb:KCNA9(gene name synonym)|uniprotkb:KVLQT1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Haitin et al. (2009)	pubmed:19521339|imex:IM-14118|mint:MINT-7297773|doi:10.1038/emboj.2009.157	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7043736|mint:MINT-7297878|imex:IM-14118-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O|mint:MINT-7297901(identity)	refseq:NP_000209.2|refseq:NP_861463.1|ensembl:ENSG00000053918(gene)|ensembl:ENST00000155840(transcript)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|mint:P51787|rcsb pdb:3BJ4|rcsb pdb:3HFC|rcsb pdb:3HFE|rcsb pdb:4UMO|rcsb pdb:4V0C|rcsb pdb:6MIE|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|reactome:R-HSA-1296072|reactome:R-HSA-5576890|reactome:R-HSA-5576893|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|dip:DIP-27591N|dip:DIP-29941N|mint:MINT-7297886(identity)	-	-	caution:This sequence has been withdrawn from Uniprot.|crc64:ADFCA9E2B9763B21	figure legend:f5a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/11/09	2014/10/16	rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606	rogid:w5Bp2fzyW56IIPAgVjXWgOOAlr49606	intact-crc:11AE0182C64F71CC|rigid:oyRJG+tP+dGZBp2xCoQSBlVqP9M	false	-	binding-associated region:352-504(MINT-7297889)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)