#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9FKG1	uniprotkb:Q39026	intact:EBI-2360943|uniprotkb:Q8L909|uniprotkb:Q9C5M2|ensemblplants:AT5G61600.1	intact:EBI-349548|ensemblplants:AT2G43790.1	psi-mi:ef104_arath(display_long)|uniprotkb:ERF104(gene name)|psi-mi:ERF104(display_short)|uniprotkb:K11J9.13(orf name)|uniprotkb:At5g61600(locus name)	psi-mi:mpk6_arath(display_long)|uniprotkb:MPK6(gene name)|psi-mi:MPK6(display_short)|uniprotkb:At2g43790(locus name)|uniprotkb:F18O19.10(orf name)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Bethke et al. (2009)	pubmed:19416906|imex:IM-14723	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-2360959|imex:IM-14723-1|dip:DIP-103816E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_200968.1|dip:DIP-48849N|ensemblplants:AT5G61600(gene)|ensemblplants:AT5G61600.1(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0009873"(ethylene-activated signaling pathway)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051301"(cell division)|interpro:IPR001471(Pathogenesis-related transcriptional factor and ERF, DNA-binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR036955	refseq:NP_181907.1|ensemblplants:AT2G43790(gene)|ensemblplants:AT2G43790.1(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009409"(response to cold)|go:"GO:0009524"(phragmoplast)|go:"GO:0009555"(pollen development)|go:"GO:0009574"(preprophase band)|go:"GO:0009620"(response to fungus)|go:"GO:0009626"(plant-type hypersensitive response)|go:"GO:0009651"(response to salt stress)|go:"GO:0009723"(response to ethylene)|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009738"(abscisic acid-activated signaling pathway)|go:"GO:0009864"(induced systemic resistance, jasmonic acid mediated signaling pathway)|go:"GO:0010082"(regulation of root meristem growth)|go:"GO:0010120"(camalexin biosynthetic process)|go:"GO:0010150"(leaf senescence)|go:"GO:0010183"(pollen tube guidance)|go:"GO:0010224"(response to UV-B)|go:"GO:0010229"(inflorescence development)|go:"GO:0019902"(phosphatase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0048364"(root development)|go:"GO:0048481"(plant ovule development)|go:"GO:0050826"(response to freezing)|go:"GO:0051301"(cell division)|go:"GO:0051510"(regulation of unidimensional cell growth)|go:"GO:0080136"(priming of cellular response to stress)|go:"GO:0090333"(regulation of stomatal closure)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902065"(response to L-glutamate)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5CI6|rcsb pdb:6DTL|dip:DIP-31825N	psi-mi:"MI:0465"(dip)	-	-	figure legend:Figure 1|inhibition:"flg22 peptide (QRLSTGSRINSAKDDAAGLQIA)"|comment:"Kinase inactive MPK6 ( Lys92Arg or Ser229Ala , Ser232Ala) interacted with ERF104 independently of flg22 treatment."|comment:Treatment with aminoethoxyvinylglycine or silver ions removed flg22 inhibition of the interaction.|comment:The authors concluded that inhibition of interaction between MPK6 and ERF104 by flg22 required ethylene bio-synthesis and signalling.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:3702(arath-mesophyll)|taxid:3702(Arabidopsis thaliana mesophyll)	-	2009/06/30	2017/06/30	rogid:Nbe1icOulHmbz95GaDVIJOk4G+o3702	rogid:E5m2JeEVpG2vsn/SIqtcxY3Oqp83702	intact-crc:1F73F78A8A0174F5|rigid:96wiDInoih5oGRjk6U3FAP4YLYk	false	cyan fluorescent protein tag:?-?	yellow fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q9FKG1	uniprotkb:Q39026	intact:EBI-2360943|uniprotkb:Q8L909|uniprotkb:Q9C5M2|ensemblplants:AT5G61600.1	intact:EBI-349548|ensemblplants:AT2G43790.1	psi-mi:ef104_arath(display_long)|uniprotkb:ERF104(gene name)|psi-mi:ERF104(display_short)|uniprotkb:K11J9.13(orf name)|uniprotkb:At5g61600(locus name)	psi-mi:mpk6_arath(display_long)|uniprotkb:MPK6(gene name)|psi-mi:MPK6(display_short)|uniprotkb:At2g43790(locus name)|uniprotkb:F18O19.10(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Bethke et al. (2009)	pubmed:19416906|imex:IM-14723	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-2360996|imex:IM-14723-2	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_200968.1|dip:DIP-48849N|ensemblplants:AT5G61600(gene)|ensemblplants:AT5G61600.1(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0009873"(ethylene-activated signaling pathway)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051301"(cell division)|interpro:IPR001471(Pathogenesis-related transcriptional factor and ERF, DNA-binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR036955	refseq:NP_181907.1|ensemblplants:AT2G43790(gene)|ensemblplants:AT2G43790.1(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009409"(response to cold)|go:"GO:0009524"(phragmoplast)|go:"GO:0009555"(pollen development)|go:"GO:0009574"(preprophase band)|go:"GO:0009620"(response to fungus)|go:"GO:0009626"(plant-type hypersensitive response)|go:"GO:0009651"(response to salt stress)|go:"GO:0009723"(response to ethylene)|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009738"(abscisic acid-activated signaling pathway)|go:"GO:0009864"(induced systemic resistance, jasmonic acid mediated signaling pathway)|go:"GO:0010082"(regulation of root meristem growth)|go:"GO:0010120"(camalexin biosynthetic process)|go:"GO:0010150"(leaf senescence)|go:"GO:0010183"(pollen tube guidance)|go:"GO:0010224"(response to UV-B)|go:"GO:0010229"(inflorescence development)|go:"GO:0019902"(phosphatase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0048364"(root development)|go:"GO:0048481"(plant ovule development)|go:"GO:0050826"(response to freezing)|go:"GO:0051301"(cell division)|go:"GO:0051510"(regulation of unidimensional cell growth)|go:"GO:0080136"(priming of cellular response to stress)|go:"GO:0090333"(regulation of stomatal closure)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902065"(response to L-glutamate)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5CI6|rcsb pdb:6DTL|dip:DIP-31825N	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	-	-	comment:"MPK6 was immunoprecipitated from flg22 peptide (QRLSTGSRINSAKDDAAGLQIA) treated Arabidopsis plants."|figure legend:Figure 3C Figure 3E|resulting-ptm:"Phosphorylation of ERF104 (Q9FKG1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/30	2017/06/30	rogid:Nbe1icOulHmbz95GaDVIJOk4G+o3702	rogid:E5m2JeEVpG2vsn/SIqtcxY3Oqp83702	intact-crc:9A844A129264197F|rigid:96wiDInoih5oGRjk6U3FAP4YLYk	false	glutathione s tranferase tag:?-?|mutation:232-232,229-229|sufficient binding region:226-232|sufficient binding region:202-212	-	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:Q9FKG1	uniprotkb:Q39026	intact:EBI-2360943|uniprotkb:Q8L909|uniprotkb:Q9C5M2|ensemblplants:AT5G61600.1	intact:EBI-349548|ensemblplants:AT2G43790.1	psi-mi:ef104_arath(display_long)|uniprotkb:ERF104(gene name)|psi-mi:ERF104(display_short)|uniprotkb:K11J9.13(orf name)|uniprotkb:At5g61600(locus name)	psi-mi:mpk6_arath(display_long)|uniprotkb:MPK6(gene name)|psi-mi:MPK6(display_short)|uniprotkb:At2g43790(locus name)|uniprotkb:F18O19.10(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bethke et al. (2009)	pubmed:19416906|imex:IM-14723	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-2361692|imex:IM-14723-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_200968.1|dip:DIP-48849N|ensemblplants:AT5G61600(gene)|ensemblplants:AT5G61600.1(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0009873"(ethylene-activated signaling pathway)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051301"(cell division)|interpro:IPR001471(Pathogenesis-related transcriptional factor and ERF, DNA-binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR036955	refseq:NP_181907.1|ensemblplants:AT2G43790(gene)|ensemblplants:AT2G43790.1(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009409"(response to cold)|go:"GO:0009524"(phragmoplast)|go:"GO:0009555"(pollen development)|go:"GO:0009574"(preprophase band)|go:"GO:0009620"(response to fungus)|go:"GO:0009626"(plant-type hypersensitive response)|go:"GO:0009651"(response to salt stress)|go:"GO:0009723"(response to ethylene)|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009738"(abscisic acid-activated signaling pathway)|go:"GO:0009864"(induced systemic resistance, jasmonic acid mediated signaling pathway)|go:"GO:0010082"(regulation of root meristem growth)|go:"GO:0010120"(camalexin biosynthetic process)|go:"GO:0010150"(leaf senescence)|go:"GO:0010183"(pollen tube guidance)|go:"GO:0010224"(response to UV-B)|go:"GO:0010229"(inflorescence development)|go:"GO:0019902"(phosphatase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0048364"(root development)|go:"GO:0048481"(plant ovule development)|go:"GO:0050826"(response to freezing)|go:"GO:0051301"(cell division)|go:"GO:0051510"(regulation of unidimensional cell growth)|go:"GO:0080136"(priming of cellular response to stress)|go:"GO:0090333"(regulation of stomatal closure)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902065"(response to L-glutamate)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5CI6|rcsb pdb:6DTL|dip:DIP-31825N	-	-	-	figure legend:SFigure 1D|inhibition:flg22|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:3702(arath-mesophyll)|taxid:3702(Arabidopsis thaliana mesophyll)	-	2009/06/30	2017/06/30	rogid:Nbe1icOulHmbz95GaDVIJOk4G+o3702	rogid:E5m2JeEVpG2vsn/SIqtcxY3Oqp83702	intact-crc:30EBCEAA2785D4AD|rigid:96wiDInoih5oGRjk6U3FAP4YLYk	false	ha tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9FKG1	ensemblgenomes:At5g44420	intact:EBI-2360943|uniprotkb:Q8L909|uniprotkb:Q9C5M2|ensemblplants:AT5G61600.1	intact:EBI-6620369	psi-mi:ef104_arath(display_long)|uniprotkb:ERF104(gene name)|psi-mi:ERF104(display_short)|uniprotkb:K11J9.13(orf name)|uniprotkb:At5g61600(locus name)	psi-mi:pdf1_2_arath_gene(display_short)|psi-mi:At5g44420(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Bethke et al. (2009)	pubmed:19416906|imex:IM-14723	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-2361715|imex:IM-14723-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_200968.1|dip:DIP-48849N|ensemblplants:AT5G61600(gene)|ensemblplants:AT5G61600.1(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0009873"(ethylene-activated signaling pathway)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051301"(cell division)|interpro:IPR001471(Pathogenesis-related transcriptional factor and ERF, DNA-binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR036955	-	-	-	-	figure legend:Figure 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	-	2009/06/30	2017/06/30	rogid:Nbe1icOulHmbz95GaDVIJOk4G+o3702	-	intact-crc:B27D4A97FB5F07D8	false	strep tag:?-?	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)