#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q969V5	uniprotkb:P63165	intact:EBI-744120|uniprotkb:Q7Z431|uniprotkb:Q9H9B5|uniprotkb:B5M497|ensembl:ENSP00000264198	intact:EBI-80140|uniprotkb:P55856|uniprotkb:Q6FGG0|uniprotkb:Q6NZ62|uniprotkb:Q93068|intact:EBI-28970052|ensembl:ENSP00000376076|ensembl:ENSP00000376077|uniprotkb:B2R4I5|uniprotkb:A8MUS8	psi-mi:mul1_human(display_long)|uniprotkb:C1orf166(gene name synonym)|uniprotkb:MAPL(gene name synonym)|uniprotkb:MULAN(gene name synonym)|uniprotkb:RNF218(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase MUL1(gene name synonym)|uniprotkb:GIDE(gene name synonym)|uniprotkb:Mitochondrial-anchored protein ligase(gene name synonym)|uniprotkb:RING finger protein 218(gene name synonym)|uniprotkb:MUL1(gene name)|psi-mi:MUL1(display_short)|uniprotkb:Growth inhibition and death E3 ligase(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 266(gene name synonym)|uniprotkb:E3 SUMO-protein ligase MUL1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NFKB 1(gene name synonym)|uniprotkb:Protein Hades(gene name synonym)	psi-mi:sumo1_human(display_long)|uniprotkb:SUMO1(gene name)|psi-mi:SUMO1(display_short)|uniprotkb:Sentrin(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym)|uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym)|uniprotkb:Ubiquitin-like protein UBL1(gene name synonym)|uniprotkb:GAP-modifying protein 1(gene name synonym)|uniprotkb:SMT3 homolog 3(gene name synonym)|uniprotkb:SMT3C(gene name synonym)|uniprotkb:SMT3H3(gene name synonym)|uniprotkb:UBL1(gene name synonym)|uniprotkb:OK/SW-cl.43(orf name)	psi-mi:"MI:0096"(pull down)	Braschi et al. (2009)	pubmed:19407830|imex:IM-13876|mint:MINT-7218769|doi:10.1038/embor.2009.86	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6987810|mint:MINT-7218800|imex:IM-13876-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078820.2|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050821"(protein stabilization)|ensembl:ENST00000264198(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0002039"(p53 binding)|ensembl:ENSG00000090432(gene)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1901028"(regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR022170|mint:Q969V5|rcsb pdb:6K2K|go:"GO:0051898"(negative regulation of protein kinase B signaling)|rcsb pdb:6M2C|rcsb pdb:6M2D|reactome:R-HSA-5689880|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0051646"(mitochondrion localization)|mint:MINT-7218802(identity)	refseq:NP_001005781.1|refseq:NP_003343.1|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P63165|rcsb pdb:1A5R|rcsb pdb:1TGZ|rcsb pdb:1WYW|rcsb pdb:1Y8R|rcsb pdb:1Z5S|rcsb pdb:2ASQ|rcsb pdb:2BF8|rcsb pdb:2G4D|rcsb pdb:2IO2|rcsb pdb:2IY0|rcsb pdb:2IY1|rcsb pdb:2KQS|rcsb pdb:2LAS|rcsb pdb:2MW5|rcsb pdb:2N1A|rcsb pdb:2N1V|rcsb pdb:2PE6|rcsb pdb:2UYZ|rcsb pdb:2VRR|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:3RZW|rcsb pdb:3UIP|rcsb pdb:4WJN|rcsb pdb:4WJO|rcsb pdb:4WJP|rcsb pdb:4WJQ|rcsb pdb:5AEK|rcsb pdb:5B7A|rcsb pdb:5ELJ|rcsb pdb:5GHD|rcsb pdb:6EOP|rcsb pdb:6EOT|rcsb pdb:6J4I|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6K5T|rcsb pdb:6TRW|rcsb pdb:6UYO|rcsb pdb:6UYP|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|ensembl:ENSG00000116030(gene)|ensembl:ENST00000392245(transcript)|ensembl:ENST00000392246(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010621"(negative regulation of transcription by transcription factor localization)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019899"(enzyme binding)|rcsb pdb:6UYU|rcsb pdb:6UYV|rcsb pdb:6UYX|rcsb pdb:6UYY|rcsb pdb:6UYZ|rcsb pdb:6V7P|rcsb pdb:6V7Q|rcsb pdb:6V7R|rcsb pdb:6UYT|rcsb pdb:6V7S|rcsb pdb:6WW3|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-4551638|reactome:R-HSA-877312|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000392244|ensembl:ENSP00000376075|ensembl:ENSP00000376076|ensembl:ENSP00000376077|refseq:NP_001005782.1|dip:DIP-29080N|mint:MINT-7218803(identity)	-	-	-	figure legend:F1A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/07/13	2014/10/16	rogid:THGOIEcH68uAtym/UHsPpBYSbMA9606	rogid:mflrn+v4fHL8UdmLodfZBZA6eAQ9606	intact-crc:0F3B74F21855AD4A|rigid:kv+5/feZMTFvucgazXZY/A3f6do	false	binding-associated region:257-352(MINT-7218808)|biotin tag:?-?(MINT-7218805)	his tag:?-?(MINT-7218811)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q969V5	uniprotkb:P0CG48	intact:EBI-744120|uniprotkb:Q7Z431|uniprotkb:Q9H9B5|uniprotkb:B5M497|ensembl:ENSP00000264198	intact:EBI-3390054|ensembl:ENSP00000344818|ensembl:ENSP00000441543|uniprotkb:Q9BWD6|uniprotkb:P02249|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q9UPK7|uniprotkb:P62988|uniprotkb:P02250|uniprotkb:Q9UEK8|uniprotkb:Q6LDU5|uniprotkb:Q91888|uniprotkb:Q6LBL4|uniprotkb:Q9UEF2|uniprotkb:Q29120|uniprotkb:P02248|uniprotkb:Q9BX98|uniprotkb:Q9UEG1	psi-mi:mul1_human(display_long)|uniprotkb:C1orf166(gene name synonym)|uniprotkb:MAPL(gene name synonym)|uniprotkb:MULAN(gene name synonym)|uniprotkb:RNF218(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase MUL1(gene name synonym)|uniprotkb:GIDE(gene name synonym)|uniprotkb:Mitochondrial-anchored protein ligase(gene name synonym)|uniprotkb:RING finger protein 218(gene name synonym)|uniprotkb:MUL1(gene name)|psi-mi:MUL1(display_short)|uniprotkb:Growth inhibition and death E3 ligase(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 266(gene name synonym)|uniprotkb:E3 SUMO-protein ligase MUL1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NFKB 1(gene name synonym)|uniprotkb:Protein Hades(gene name synonym)	psi-mi:ubc_human(display_long)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:"MI:0096"(pull down)	Braschi et al. (2009)	pubmed:19407830|imex:IM-13876|mint:MINT-7218769|doi:10.1038/embor.2009.86	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6987831|mint:MINT-7218815|imex:IM-13876-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078820.2|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050821"(protein stabilization)|ensembl:ENST00000264198(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0002039"(p53 binding)|ensembl:ENSG00000090432(gene)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1901028"(regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR022170|mint:Q969V5|rcsb pdb:6K2K|go:"GO:0051898"(negative regulation of protein kinase B signaling)|rcsb pdb:6M2C|rcsb pdb:6M2D|reactome:R-HSA-5689880|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0051646"(mitochondrion localization)|mint:MINT-7218821(identity)	reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-1253288|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5656121|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5689880|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-9613829|ensembl:ENSG00000150991(gene)|ensembl:ENST00000339647(transcript)|ensembl:ENST00000536769(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG48|rcsb pdb:1C3T|rcsb pdb:1CMX|rcsb pdb:1D3Z|rcsb pdb:1F9J|rcsb pdb:1FXT|rcsb pdb:1G6J|rcsb pdb:1GJZ|rcsb pdb:1NBF|rcsb pdb:1OGW|rcsb pdb:1Q5W|rcsb pdb:1S1Q|rcsb pdb:1SIF|rcsb pdb:1TBE|rcsb pdb:1UBI|rcsb pdb:1UBQ|rcsb pdb:1UD7|rcsb pdb:1XD3|rcsb pdb:1XQQ|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:1ZGU|rcsb pdb:1ZO6|rcsb pdb:2AYO|rcsb pdb:2BGF|rcsb pdb:2DEN|rcsb pdb:2FUH|rcsb pdb:2G45|rcsb pdb:2GBJ|rcsb pdb:2GBK|rcsb pdb:2GBM|rcsb pdb:2GBN|rcsb pdb:2GBR|rcsb pdb:2GMI|rcsb pdb:2HTH|rcsb pdb:2IBI|rcsb pdb:2J7Q|rcsb pdb:2JF5|rcsb pdb:2JRI|interpro:IPR000626(Ubiquitin)|rcsb pdb:2JY6|rcsb pdb:2JZZ|rcsb pdb:2K25|rcsb pdb:2K6D|rcsb pdb:2K8B|rcsb pdb:2K8C|rcsb pdb:2KDF|rcsb pdb:2KHW|rcsb pdb:2KJH|rcsb pdb:2KLG|rcsb pdb:2KN5|rcsb pdb:2KX0|rcsb pdb:2L3Z|rcsb pdb:2LD9|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LZ6|rcsb pdb:2MBO|rcsb pdb:2MBQ|rcsb pdb:2MCN|rcsb pdb:2MJ5|rcsb pdb:2MOR|rcsb pdb:2MRE|rcsb pdb:2MWS|rcsb pdb:2N2K|rcsb pdb:2NR2|rcsb pdb:2O6V|rcsb pdb:2OJR|rcsb pdb:2PE9|rcsb pdb:2PEA|rcsb pdb:2RR9|rcsb pdb:2RU6|rcsb pdb:2MI8|rcsb pdb:2W9N|rcsb pdb:2WDT|rcsb pdb:2XEW|rcsb pdb:2Y5B|rcsb pdb:2Z59|rcsb pdb:2ZCB|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3A33|rcsb pdb:3ALB|rcsb pdb:3AUL|rcsb pdb:3B08|rcsb pdb:3B0A|rcsb pdb:3BY4|rcsb pdb:3C0R|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EEC|rcsb pdb:3EFU|rcsb pdb:3EHV|rcsb pdb:3H7P|rcsb pdb:3H7S|rcsb pdb:3HM3|rcsb pdb:3I3T|rcsb pdb:3IFW|rcsb pdb:3IHP|rcsb pdb:3JSV|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:3LDZ|rcsb pdb:3MHS|rcsb pdb:3MTN|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3N3K|rcsb pdb:3NS8|rcsb pdb:3O65|rcsb pdb:3OFI|rcsb pdb:3OJ3|rcsb pdb:3OJ4|rcsb pdb:3ONS|rcsb pdb:3PRM|rcsb pdb:3PT2|rcsb pdb:3Q3F|rcsb pdb:3RUL|rcsb pdb:3PTF|rcsb pdb:3TMP|rcsb pdb:3U30|rcsb pdb:3UGB|rcsb pdb:3V6C|rcsb pdb:3V6E|rcsb pdb:3VFK|rcsb pdb:3VUW|rcsb pdb:3VUX|rcsb pdb:3VUY|rcsb pdb:3WXE|rcsb pdb:3WXF|rcsb pdb:3ZLZ|rcsb pdb:3ZNH|rcsb pdb:3ZNI|rcsb pdb:3ZNZ|rcsb pdb:4AP4|rcsb pdb:4AUQ|rcsb pdb:4BOS|rcsb pdb:4BOZ|rcsb pdb:4BVU|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4FJV|rcsb pdb:4HK2|rcsb pdb:4HXD|rcsb pdb:4I6L|rcsb pdb:4I6N|rcsb pdb:4IG7|rcsb pdb:4IUM|rcsb pdb:4JQW|rcsb pdb:4K1R|rcsb pdb:4K7S|rcsb pdb:4K7U|rcsb pdb:4K7W|rcsb pdb:4KSK|rcsb pdb:4KSL|rcsb pdb:4LCD|rcsb pdb:4LDT|rcsb pdb:4MDK|rcsb pdb:4MM3|rcsb pdb:4MSM|rcsb pdb:4MSQ|rcsb pdb:4NQK|rcsb pdb:4UN2|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZP|rcsb pdb:4XOK|rcsb pdb:4XOL|rcsb pdb:4ZQS|rcsb pdb:5A5B|rcsb pdb:5AF4|rcsb pdb:5AF5|rcsb pdb:5AF6|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5B83|rcsb pdb:5C7J|rcsb pdb:5C7M|rcsb pdb:5E6J|rcsb pdb:5H07|rcsb pdb:5NL4|rcsb pdb:5NLF|rcsb pdb:5NLI|rcsb pdb:5NMC|rcsb pdb:5OE7|rcsb pdb:5OHV|rcsb pdb:5OXH|rcsb pdb:5OXI|rcsb pdb:5UDH|rcsb pdb:5WQ4|rcsb pdb:5ZQ3|rcsb pdb:5ZQ4|rcsb pdb:5ZQ5|rcsb pdb:5ZQ6|rcsb pdb:5ZQ7|rcsb pdb:6A43|rcsb pdb:6A44|rcsb pdb:6AQR|rcsb pdb:6B7M|rcsb pdb:6B7O|rcsb pdb:6K2U|rcsb pdb:6KBE|rcsb pdb:6N13|rcsb pdb:6N6R|rcsb pdb:6NQA|rcsb pdb:6NXK|rcsb pdb:6OI4|rcsb pdb:6P5B|rcsb pdb:6Q00|rcsb pdb:6QML|rcsb pdb:6RYA|rcsb pdb:6S53|rcsb pdb:6SQR|rcsb pdb:6T7F|rcsb pdb:6T9L|rcsb pdb:6TNF|rcsb pdb:6TTU|rcsb pdb:6TUV|rcsb pdb:6TXB|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6EQI|rcsb pdb:6UMS|rcsb pdb:6UPU|rcsb pdb:6V5D|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:6VEN|rcsb pdb:6W9D|rcsb pdb:6W9R|rcsb pdb:6W9S|rcsb pdb:6WJD|rcsb pdb:6WKR|rcsb pdb:6WTG|rcsb pdb:6Z7V|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|rcsb pdb:7K6P|rcsb pdb:7K6Q|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|refseq:NP_066289.3|mint:MINT-7218817(identity)	-	-	-	figure legend:F1C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/07/13	2014/10/16	rogid:THGOIEcH68uAtym/UHsPpBYSbMA9606	rogid:BM+LHQXjMaUn8RZfq1h9jsAAqcs9606	intact-crc:9AECAF235516B06E|rigid:fRZQKZo4PqEe+zZPKZMfKhjLhX8	false	biotin tag:?-?(MINT-7218824)|binding-associated region:257-352(MINT-7218822)	his tag:?-?(MINT-7218818)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q969V5	uniprotkb:P63279	intact:EBI-744120|uniprotkb:Q7Z431|uniprotkb:Q9H9B5|uniprotkb:B5M497|ensembl:ENSP00000264198	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:mul1_human(display_long)|uniprotkb:C1orf166(gene name synonym)|uniprotkb:MAPL(gene name synonym)|uniprotkb:MULAN(gene name synonym)|uniprotkb:RNF218(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase MUL1(gene name synonym)|uniprotkb:GIDE(gene name synonym)|uniprotkb:Mitochondrial-anchored protein ligase(gene name synonym)|uniprotkb:RING finger protein 218(gene name synonym)|uniprotkb:MUL1(gene name)|psi-mi:MUL1(display_short)|uniprotkb:Growth inhibition and death E3 ligase(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 266(gene name synonym)|uniprotkb:E3 SUMO-protein ligase MUL1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NFKB 1(gene name synonym)|uniprotkb:Protein Hades(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Braschi et al. (2009)	pubmed:19407830|imex:IM-13876|mint:MINT-7218769|doi:10.1038/embor.2009.86	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6987892|mint:MINT-7218879|imex:IM-13876-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078820.2|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050821"(protein stabilization)|ensembl:ENST00000264198(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0002039"(p53 binding)|ensembl:ENSG00000090432(gene)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1901028"(regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR022170|mint:Q969V5|rcsb pdb:6K2K|go:"GO:0051898"(negative regulation of protein kinase B signaling)|rcsb pdb:6M2C|rcsb pdb:6M2D|reactome:R-HSA-5689880|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0051646"(mitochondrion localization)|mint:MINT-7218885(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|mint:MINT-7218881(identity)	-	-	-	figure legend:F4B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2009/07/13	2014/10/16	rogid:THGOIEcH68uAtym/UHsPpBYSbMA9606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:91EC51BB0B0952EE|rigid:Qye6HlKhYp0hxshpMd7wapquuSY	false	flag tag:?-?(MINT-7218886)	yellow fluorescent protein tag:?-?(MINT-7218882)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P63279	uniprotkb:Q969V5	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-744120|uniprotkb:Q7Z431|uniprotkb:Q9H9B5|uniprotkb:B5M497|ensembl:ENSP00000264198	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:mul1_human(display_long)|uniprotkb:C1orf166(gene name synonym)|uniprotkb:MAPL(gene name synonym)|uniprotkb:MULAN(gene name synonym)|uniprotkb:RNF218(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase MUL1(gene name synonym)|uniprotkb:GIDE(gene name synonym)|uniprotkb:Mitochondrial-anchored protein ligase(gene name synonym)|uniprotkb:RING finger protein 218(gene name synonym)|uniprotkb:MUL1(gene name)|psi-mi:MUL1(display_short)|uniprotkb:Growth inhibition and death E3 ligase(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 266(gene name synonym)|uniprotkb:E3 SUMO-protein ligase MUL1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NFKB 1(gene name synonym)|uniprotkb:Protein Hades(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Braschi et al. (2009)	pubmed:19407830|imex:IM-13876|mint:MINT-7218769|doi:10.1038/embor.2009.86	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6987991|mint:MINT-7218842|imex:IM-13876-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|mint:MINT-7218844(identity)	refseq:NP_078820.2|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050821"(protein stabilization)|ensembl:ENST00000264198(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0002039"(p53 binding)|ensembl:ENSG00000090432(gene)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1901028"(regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR022170|mint:Q969V5|rcsb pdb:6K2K|go:"GO:0051898"(negative regulation of protein kinase B signaling)|rcsb pdb:6M2C|rcsb pdb:6M2D|reactome:R-HSA-5689880|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0051646"(mitochondrion localization)|mint:MINT-7218848(identity)	-	-	-	figure legend:F1D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2009/07/13	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:THGOIEcH68uAtym/UHsPpBYSbMA9606	intact-crc:64EDC582141632DF|rigid:Qye6HlKhYp0hxshpMd7wapquuSY	false	yellow fluorescent protein tag:?-?(MINT-7218845)	flag tag:?-?(MINT-7218851)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)