#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9WV48 uniprotkb:Q9Z214-2 intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100 intact:EBI-2338999|ensembl:ENSRNOP00000066634 psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym) psi-mi:q9z214-2(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)|uniprotkb:1b(isoform synonym) psi-mi:"MI:0028"(cosedimentation in solution) Hayashi et al. (2009) imex:IM-12174|pubmed:19345194 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2339007|imex:IM-12174-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1 intact:EBI-2338940(isoform-parent)|ensembl:ENSRNOG00000047014(gene)|ensembl:ENSRNOT00000073871(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Figs 1B, 1C, 1E|comment:Mutation of a proline in the Homer Binding site of Shak1 prevented binding to wild-type Shak1 but this could not be mapped in this construct.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/20 2014/10/16 rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116 rogid:VlvUJbhnBNfdV6VfZoNYluKxB4g10116 intact-crc:AABD676FFF8E47DB|rigid:k4WR4Mzja809q4g+9pzHYtZXF+w false sufficient binding region:577-699,1464-1521,2010-2167 mutation decreasing interaction:24-24 1 1 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q5XIG5 uniprotkb:Q9Z214-2 intact:EBI-2339050|ensembl:ENSRNOP00000026070|ensembl:ENSRNOP00000075132 intact:EBI-2338999|ensembl:ENSRNOP00000066634 psi-mi:gkap1_rat(display_long)|uniprotkb:Gkap1(gene name)|psi-mi:Gkap1(display_short) psi-mi:q9z214-2(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)|uniprotkb:1b(isoform synonym) psi-mi:"MI:0028"(cosedimentation in solution) Hayashi et al. (2009) imex:IM-12174|pubmed:19345194 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2339059|imex:IM-12174-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1306955|refseq:NP_001012160.1|refseq:XP_006253621.1|refseq:XP_017456077.1|ensembl:ENSRNOG00000019272(gene)|ensembl:ENSRNOT00000026070(transcript)|ensembl:ENSRNOT00000083408(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|interpro:IPR026109 intact:EBI-2338940(isoform-parent)|ensembl:ENSRNOG00000047014(gene)|ensembl:ENSRNOT00000073871(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Figs 2A, 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/20 2014/10/16 rogid:L/CdICCKlnPgPKUcpRumhDoMWIo10116 rogid:VlvUJbhnBNfdV6VfZoNYluKxB4g10116 intact-crc:02DCA28321E8A853|rigid:UViMcDWrrvtMQ3g2e7zIRXzG15E false sufficient binding region:?-? - 1 1 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q5XIG5 uniprotkb:Q9WV48 intact:EBI-2339050|ensembl:ENSRNOP00000026070|ensembl:ENSRNOP00000075132 intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100 psi-mi:gkap1_rat(display_long)|uniprotkb:Gkap1(gene name)|psi-mi:Gkap1(display_short) psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Hayashi et al. (2009) imex:IM-12174|pubmed:19345194 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2339059|imex:IM-12174-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1306955|refseq:NP_001012160.1|refseq:XP_006253621.1|refseq:XP_017456077.1|ensembl:ENSRNOG00000019272(gene)|ensembl:ENSRNOT00000026070(transcript)|ensembl:ENSRNOT00000083408(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|interpro:IPR026109 rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1 psi-mi:"MI:0469"(intact) - - figure legend:Figs 2A, 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/20 2014/10/16 rogid:L/CdICCKlnPgPKUcpRumhDoMWIo10116 rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116 intact-crc:02DCA28321E8A853|rigid:UViMcDWrrvtMQ3g2e7zIRXzG15E false sufficient binding region:?-? sufficient binding region:577-699,1464-1521,2010-2167 1 1 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Z214-2 uniprotkb:Q9Z214-3 intact:EBI-2338999|ensembl:ENSRNOP00000066634 intact:EBI-2339003 psi-mi:q9z214-2(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)|uniprotkb:1b(isoform synonym) psi-mi:q9z214-3(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)|uniprotkb:1a(isoform synonym)|uniprotkb:Vesl(isoform synonym) psi-mi:"MI:0028"(cosedimentation in solution) Hayashi et al. (2009) imex:IM-12174|pubmed:19345194 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2339079|imex:IM-12174-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338940(isoform-parent)|ensembl:ENSRNOG00000047014(gene)|ensembl:ENSRNOT00000073871(transcript) intact:EBI-2338940(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Figs 2C, 2D|comment:A competitive interaction between Homer1a and Homer1b on Shank prevents the complex formation.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/20 2014/10/16 rogid:VlvUJbhnBNfdV6VfZoNYluKxB4g10116 rogid:hQ8TcVLkUrkXFG/JEAXVgf265Pc10116 intact-crc:6F164093A19B7A55|rigid:TA/nZaYr0Bwyn9E+nrUaUgFPfdg false mutation decreasing interaction:24-24 - 1 - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Z214-2 uniprotkb:Q9WV48 intact:EBI-2338999|ensembl:ENSRNOP00000066634 intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100 psi-mi:q9z214-2(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)|uniprotkb:1b(isoform synonym) psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Hayashi et al. (2009) imex:IM-12174|pubmed:19345194 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2339079|imex:IM-12174-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338940(isoform-parent)|ensembl:ENSRNOG00000047014(gene)|ensembl:ENSRNOT00000073871(transcript) rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1 psi-mi:"MI:0469"(intact) - - figure legend:Figs 2C, 2D|comment:A competitive interaction between Homer1a and Homer1b on Shank prevents the complex formation.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/20 2014/10/16 rogid:VlvUJbhnBNfdV6VfZoNYluKxB4g10116 rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116 intact-crc:6F164093A19B7A55|rigid:TA/nZaYr0Bwyn9E+nrUaUgFPfdg false mutation decreasing interaction:24-24 sufficient binding region:577-699,1464-1521,2010-2167 1 1 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9NSC5-1 uniprotkb:Q9WV48 intact:EBI-748433|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026 intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100 psi-mi:q9nsc5-1(display_long)|uniprotkb:3a(isoform synonym)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short) psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Hayashi et al. (2009) imex:IM-12174|pubmed:19345194 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2339092|imex:IM-12174-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-748420(home3_human)|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript) rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1 psi-mi:"MI:0469"(intact) - - figure legend:Figs 2E, 2F|comment:Interaction is inhibited by phosphorylation of Homer3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/20 2014/10/16 rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606 rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116 intact-crc:FCC7D0ACE7CD6BBE|rigid:Yr3z6ZeUjDc2p4YbxBrN4HEaFlo false - sufficient binding region:577-699,1464-1521,2010-2167 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Z214-2 uniprotkb:Q9Z214-2 intact:EBI-2338999|ensembl:ENSRNOP00000066634 intact:EBI-2338999|ensembl:ENSRNOP00000066634 psi-mi:q9z214-2(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)|uniprotkb:1b(isoform synonym) psi-mi:q9z214-2(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)|uniprotkb:1b(isoform synonym) psi-mi:"MI:0028"(cosedimentation in solution) Hayashi et al. (2009) imex:IM-12174|pubmed:19345194 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2339102|imex:IM-12174-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338940(isoform-parent)|ensembl:ENSRNOG00000047014(gene)|ensembl:ENSRNOT00000073871(transcript) intact:EBI-2338940(isoform-parent)|ensembl:ENSRNOG00000047014(gene)|ensembl:ENSRNOT00000073871(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 4C, 4F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/20 2014/10/16 rogid:VlvUJbhnBNfdV6VfZoNYluKxB4g10116 rogid:VlvUJbhnBNfdV6VfZoNYluKxB4g10116 intact-crc:E4E6BCE7BEDBC25A|rigid:JvdBvE+ojguqIsZhGGMxNucu/Qk false mutation decreasing interaction:332-332,337-337|necessary binding region:329-354 mutation decreasing interaction:332-332,337-337|necessary binding region:329-354 4 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9WV48 uniprotkb:Q9Z214-2 intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100 intact:EBI-2338999|ensembl:ENSRNOP00000066634 psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym) psi-mi:q9z214-2(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)|uniprotkb:1b(isoform synonym) psi-mi:"MI:0067"(light scattering) Hayashi et al. (2009) imex:IM-12174|pubmed:19345194 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2339022|imex:IM-12174-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1 intact:EBI-2338940(isoform-parent)|ensembl:ENSRNOG00000047014(gene)|ensembl:ENSRNOT00000073871(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Figs 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/20 2014/10/16 rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116 rogid:VlvUJbhnBNfdV6VfZoNYluKxB4g10116 intact-crc:AD1A949A8E0A7884|rigid:k4WR4Mzja809q4g+9pzHYtZXF+w false sufficient binding region:577-699,1464-1521,2010-2167 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z214-2 uniprotkb:Q9Z214-2 intact:EBI-2338999|ensembl:ENSRNOP00000066634 intact:EBI-2338999|ensembl:ENSRNOP00000066634 psi-mi:q9z214-2(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)|uniprotkb:1b(isoform synonym) psi-mi:q9z214-2(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)|uniprotkb:1b(isoform synonym) psi-mi:"MI:0067"(light scattering) Hayashi et al. (2009) imex:IM-12174|pubmed:19345194 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2339140|imex:IM-12174-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338940(isoform-parent)|ensembl:ENSRNOG00000047014(gene)|ensembl:ENSRNOT00000073871(transcript) intact:EBI-2338940(isoform-parent)|ensembl:ENSRNOG00000047014(gene)|ensembl:ENSRNOT00000073871(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/20 2014/10/16 rogid:VlvUJbhnBNfdV6VfZoNYluKxB4g10116 rogid:VlvUJbhnBNfdV6VfZoNYluKxB4g10116 intact-crc:E04CF5C74148ECC1|rigid:JvdBvE+ojguqIsZhGGMxNucu/Qk false mutation decreasing interaction:332-332,337-337|necessary binding region:329-354 mutation decreasing interaction:332-332,337-337|necessary binding region:329-354 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WV48 uniprotkb:Q9Z214-2 intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100 intact:EBI-2338999|ensembl:ENSRNOP00000066634 psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym) psi-mi:q9z214-2(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)|uniprotkb:1b(isoform synonym) psi-mi:"MI:0040"(electron microscopy) Hayashi et al. (2009) imex:IM-12174|pubmed:19345194 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2339040|imex:IM-12174-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1 intact:EBI-2338940(isoform-parent)|ensembl:ENSRNOG00000047014(gene)|ensembl:ENSRNOT00000073871(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Figs 1I|comment:The Homer and Shank mixture showed a mesh-like structure in electron microscopic images. The mesh appears to contain hubs, possibly representing Shank oligomerized via its SAM domain and linked by the filamentous Homer.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/20 2014/10/16 rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116 rogid:VlvUJbhnBNfdV6VfZoNYluKxB4g10116 intact-crc:ED2C3DF9093D27AA|rigid:k4WR4Mzja809q4g+9pzHYtZXF+w false sufficient binding region:577-699,1464-1521,2010-2167 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z214-2 uniprotkb:Q9Z214-2 intact:EBI-2338999|ensembl:ENSRNOP00000066634 intact:EBI-2338999|ensembl:ENSRNOP00000066634 psi-mi:q9z214-2(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)|uniprotkb:1b(isoform synonym) psi-mi:q9z214-2(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)|uniprotkb:1b(isoform synonym) psi-mi:"MI:0071"(molecular sieving) Hayashi et al. (2009) imex:IM-12174|pubmed:19345194 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2339118|imex:IM-12174-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338940(isoform-parent)|ensembl:ENSRNOG00000047014(gene)|ensembl:ENSRNOT00000073871(transcript) intact:EBI-2338940(isoform-parent)|ensembl:ENSRNOG00000047014(gene)|ensembl:ENSRNOT00000073871(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 4C, 4F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/20 2014/10/16 rogid:VlvUJbhnBNfdV6VfZoNYluKxB4g10116 rogid:VlvUJbhnBNfdV6VfZoNYluKxB4g10116 intact-crc:67320FD6AD6D7B6C|rigid:did/kXBxVVK6NS+2yFj9SIDpYq8 false myc tag:?-? mutation decreasing interaction:332-332,337-337|necessary binding region:329-354|ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Z214-2 uniprotkb:Q9Z214-2 intact:EBI-2338999|ensembl:ENSRNOP00000066634 intact:EBI-2338999|ensembl:ENSRNOP00000066634 psi-mi:q9z214-2(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)|uniprotkb:1b(isoform synonym) psi-mi:q9z214-2(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)|uniprotkb:1b(isoform synonym) psi-mi:"MI:0071"(molecular sieving) Hayashi et al. (2009) imex:IM-12174|pubmed:19345194 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2339134|imex:IM-12174-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2338940(isoform-parent)|ensembl:ENSRNOG00000047014(gene)|ensembl:ENSRNOT00000073871(transcript) intact:EBI-2338940(isoform-parent)|ensembl:ENSRNOG00000047014(gene)|ensembl:ENSRNOT00000073871(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/20 2014/10/16 rogid:VlvUJbhnBNfdV6VfZoNYluKxB4g10116 rogid:VlvUJbhnBNfdV6VfZoNYluKxB4g10116 intact-crc:A2879AA23FFF06C6|rigid:JvdBvE+ojguqIsZhGGMxNucu/Qk false myc tag:?-? myc tag:?-? 4 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)