#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q06219	uniprotkb:Q04207	intact:EBI-2337255|uniprotkb:O08690|ensembl:ENSMUSP00000028166|ensembl:ENSMUSP00000108248	intact:EBI-644400|uniprotkb:Q62025|ensembl:ENSMUSP00000025867	psi-mi:nr4a2_mouse(display_long)|uniprotkb:Nr4a2(gene name)|psi-mi:Nr4a2(display_short)|uniprotkb:Nurr1(gene name synonym)|uniprotkb:Orphan nuclear receptor NURR1(gene name synonym)|uniprotkb:NUR-related factor 1(gene name synonym)	psi-mi:tf65_mouse(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:Nfkb3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337302|imex:IM-12171-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011237335.1|refseq:XP_011237336.1|refseq:NP_001132981.1|refseq:NP_038641.1|ensembl:ENSMUSG00000026826(gene)|ensembl:ENSMUST00000028166(transcript)|ensembl:ENSMUST00000112629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017085"(response to insecticide)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0021986"(habenula development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042551"(neuron maturation)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043576"(regulation of respiratory gaseous exchange)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051866"(general adaptation syndrome)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003073(Orphan nuclear receptor, NURR type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280	refseq:NP_033071.1|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5621575|reactome:R-MMU-9020702|reactome:R-MMU-933542|rcsb pdb:2RAM|rcsb pdb:5U01|rcsb pdb:6GGR|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|ensembl:ENSMUSG00000024927(gene)|ensembl:ENSMUST00000025867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|mint:Q04207|rcsb pdb:1BFT|rcsb pdb:1IKN|rcsb pdb:1K3Z|rcsb pdb:1LE5|rcsb pdb:1LE9|rcsb pdb:1LEI|rcsb pdb:1MY5|rcsb pdb:1MY7|rcsb pdb:1OY3|rcsb pdb:1RAM|interpro:IPR037059|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2LWW|dip:DIP-6219N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 3F, 3G|agonist:Lipopolysaccharide|antagonist:"GSK3B-specific inhibitor SB216763 (SB21)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-bv2)|taxid:10090(Mouse BV2 glioma cells)	-	2009/05/14	2014/10/16	rogid:CK0Kua7DlmmUoBPZe0SdkqHeg9s10090	rogid:poiJSPJwXK2Om5pfk8z5HwFgK1o10090	intact-crc:1EBB5CAACDAE304D|rigid:DL2pBYbshuH8YENa5ROE/xJNB9c	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8CFE3	uniprotkb:Q06219	intact:EBI-2337309|uniprotkb:Q3V092|uniprotkb:Q8BK28|uniprotkb:Q8CHI2|uniprotkb:K3W4P9|ensembl:ENSMUSP00000082034	intact:EBI-2337255|uniprotkb:O08690|ensembl:ENSMUSP00000028166|ensembl:ENSMUSP00000108248	psi-mi:rcor1_mouse(display_long)|uniprotkb:Rcor1(gene name)|psi-mi:Rcor1(display_short)|uniprotkb:D12Wsu95e(gene name synonym)|uniprotkb:Kiaa0071(gene name synonym)|uniprotkb:Protein CoREST(gene name synonym)	psi-mi:nr4a2_mouse(display_long)|uniprotkb:Nr4a2(gene name)|psi-mi:Nr4a2(display_short)|uniprotkb:Nurr1(gene name synonym)|uniprotkb:Orphan nuclear receptor NURR1(gene name synonym)|uniprotkb:NUR-related factor 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337329|imex:IM-12171-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006515823.1|dip:DIP-48899N|refseq:NP_932140.1|ensembl:ENSMUSG00000037896(gene)|ensembl:ENSMUST00000084968(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1990391"(DNA repair complex)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q8CFE3|reactome:R-MMU-3214815|reactome:R-MMU-983231	refseq:XP_011237335.1|refseq:XP_011237336.1|refseq:NP_001132981.1|refseq:NP_038641.1|ensembl:ENSMUSG00000026826(gene)|ensembl:ENSMUST00000028166(transcript)|ensembl:ENSMUST00000112629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017085"(response to insecticide)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0021986"(habenula development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042551"(neuron maturation)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043576"(regulation of respiratory gaseous exchange)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051866"(general adaptation syndrome)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003073(Orphan nuclear receptor, NURR type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280	psi-mi:"MI:0469"(intact)	-	-	figure legend:Figs. 4B, 4E|agonist:Lipopolysaccharide|comment:Nr4a2-Rcor1 interaction was significantly reduced by NLK-knockdown in BV2 cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-bv2)|taxid:10090(Mouse BV2 glioma cells)	-	2009/05/14	2017/02/23	rogid:5yFpm82AhZnBT5toA6FfcvVKS3E10090	rogid:CK0Kua7DlmmUoBPZe0SdkqHeg9s10090	intact-crc:CCB29611AD2DFB04|rigid:oCVXNeZZik00p8sErejlYuBjDic	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q06219	uniprotkb:Q9UBE8	intact:EBI-2337255|uniprotkb:O08690|ensembl:ENSMUSP00000028166|ensembl:ENSMUSP00000108248	intact:EBI-366978|uniprotkb:Q6P2A3|uniprotkb:Q2PNI9|uniprotkb:B2RCX1|ensembl:ENSP00000384625	psi-mi:nr4a2_mouse(display_long)|uniprotkb:Nr4a2(gene name)|psi-mi:Nr4a2(display_short)|uniprotkb:Nurr1(gene name synonym)|uniprotkb:Orphan nuclear receptor NURR1(gene name synonym)|uniprotkb:NUR-related factor 1(gene name synonym)	psi-mi:nlk_human(display_long)|uniprotkb:NLK(gene name)|psi-mi:NLK(display_short)|uniprotkb:LAK1(gene name synonym)|uniprotkb:Nemo-like kinase(gene name synonym)|uniprotkb:Protein LAK1(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337358|imex:IM-12171-9	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011237335.1|refseq:XP_011237336.1|refseq:NP_001132981.1|refseq:NP_038641.1|ensembl:ENSMUSG00000026826(gene)|ensembl:ENSMUST00000028166(transcript)|ensembl:ENSMUST00000112629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017085"(response to insecticide)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0021986"(habenula development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042551"(neuron maturation)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043576"(regulation of respiratory gaseous exchange)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051866"(general adaptation syndrome)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003073(Orphan nuclear receptor, NURR type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280	ensembl:ENSG00000087095(gene)|ensembl:ENST00000407008(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|refseq:NP_057315.3|go:"GO:0008134"(transcription factor binding)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042501"(serine phosphorylation of STAT protein)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-HSA-4086398	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	-	-	figure legend:Figs. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/14	2014/10/16	rogid:CK0Kua7DlmmUoBPZe0SdkqHeg9s10090	rogid:RKKD4tTtOkk3Ve2gevJOI1N69ks9606	intact-crc:7E728EA4E8061D95|rigid:iyIgHyMLn2k+9ne6Pwe5j95JBrY	false	glutathione s tranferase tag:?-?	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UBE8	-	intact:EBI-366978|uniprotkb:Q6P2A3|uniprotkb:Q2PNI9|uniprotkb:B2RCX1|ensembl:ENSP00000384625	-	psi-mi:nlk_human(display_long)|uniprotkb:NLK(gene name)|psi-mi:NLK(display_short)|uniprotkb:LAK1(gene name synonym)|uniprotkb:Nemo-like kinase(gene name synonym)|uniprotkb:Protein LAK1(gene name synonym)	-	psi-mi:"MI:0424"(protein kinase assay)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:9606(human)|taxid:9606(Homo sapiens)	-	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337371|imex:IM-12171-8	-	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000087095(gene)|ensembl:ENST00000407008(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|refseq:NP_057315.3|go:"GO:0008134"(transcription factor binding)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042501"(serine phosphorylation of STAT protein)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-HSA-4086398	-	go:"GO:0004672"(protein kinase activity)|go:"GO:0046777"(protein autophosphorylation)	-	-	figure legend:Figs. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/14	2014/10/16	rogid:RKKD4tTtOkk3Ve2gevJOI1N69ks9606	-	intact-crc:5A2EF03594C7F439	false	his tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	-
uniprotkb:Q06219	ensembl:ENSMUSG00000020826	intact:EBI-2337255|uniprotkb:O08690|ensembl:ENSMUSP00000028166|ensembl:ENSMUSP00000108248	intact:EBI-2337397	psi-mi:nr4a2_mouse(display_long)|uniprotkb:Nr4a2(gene name)|psi-mi:Nr4a2(display_short)|uniprotkb:Nurr1(gene name synonym)|uniprotkb:Orphan nuclear receptor NURR1(gene name synonym)|uniprotkb:NUR-related factor 1(gene name synonym)	psi-mi:inos_mouse_gene(display_short)|psi-mi:ENSMUSG00000020826(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337405|imex:IM-12171-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:XP_011237335.1|refseq:XP_011237336.1|refseq:NP_001132981.1|refseq:NP_038641.1|ensembl:ENSMUSG00000026826(gene)|ensembl:ENSMUST00000028166(transcript)|ensembl:ENSMUST00000112629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017085"(response to insecticide)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0021986"(habenula development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042551"(neuron maturation)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043576"(regulation of respiratory gaseous exchange)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051866"(general adaptation syndrome)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003073(Orphan nuclear receptor, NURR type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280	-	-	-	-	figure legend:Figs. 4F|agonist:Lipopolysaccharide|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-bv2)|taxid:10090(Mouse BV2 glioma cells)	-	2009/05/14	2014/10/16	rogid:CK0Kua7DlmmUoBPZe0SdkqHeg9s10090	-	intact-crc:45B621B401E8CE8F	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000024401	uniprotkb:Q06219	intact:EBI-2337474	intact:EBI-2337255|uniprotkb:O08690|ensembl:ENSMUSP00000028166|ensembl:ENSMUSP00000108248	psi-mi:tnfa_mouse_gene(display_short)|psi-mi:ENSMUSG00000024401(display_long)	psi-mi:nr4a2_mouse(display_long)|uniprotkb:Nr4a2(gene name)|psi-mi:Nr4a2(display_short)|uniprotkb:Nurr1(gene name synonym)|uniprotkb:Orphan nuclear receptor NURR1(gene name synonym)|uniprotkb:NUR-related factor 1(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337476|imex:IM-12171-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011237335.1|refseq:XP_011237336.1|refseq:NP_001132981.1|refseq:NP_038641.1|ensembl:ENSMUSG00000026826(gene)|ensembl:ENSMUST00000028166(transcript)|ensembl:ENSMUST00000112629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017085"(response to insecticide)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0021986"(habenula development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042551"(neuron maturation)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043576"(regulation of respiratory gaseous exchange)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051866"(general adaptation syndrome)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003073(Orphan nuclear receptor, NURR type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280	-	-	-	figure legend:Supp. Fig. 9C|agonist:Lipopolysaccharide|comment:Binding is to the promoter region of the gene.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-bv2)|taxid:10090(Mouse BV2 glioma cells)	-	2009/05/14	2014/10/16	-	rogid:CK0Kua7DlmmUoBPZe0SdkqHeg9s10090	intact-crc:FB145840FF8A7C75	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000020826	uniprotkb:Q8CFE3	intact:EBI-2337397	intact:EBI-2337309|uniprotkb:Q3V092|uniprotkb:Q8BK28|uniprotkb:Q8CHI2|uniprotkb:K3W4P9|ensembl:ENSMUSP00000082034	psi-mi:inos_mouse_gene(display_short)|psi-mi:ENSMUSG00000020826(display_long)	psi-mi:rcor1_mouse(display_long)|uniprotkb:Rcor1(gene name)|psi-mi:Rcor1(display_short)|uniprotkb:D12Wsu95e(gene name synonym)|uniprotkb:Kiaa0071(gene name synonym)|uniprotkb:Protein CoREST(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337482|imex:IM-12171-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:XP_006515823.1|dip:DIP-48899N|refseq:NP_932140.1|ensembl:ENSMUSG00000037896(gene)|ensembl:ENSMUST00000084968(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1990391"(DNA repair complex)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q8CFE3|reactome:R-MMU-3214815|reactome:R-MMU-983231	-	-	-	figure legend:Figs. 4F|agonist:Lipopolysaccharide|comment:Binding is to the promoter region of the gene.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-bv2)|taxid:10090(Mouse BV2 glioma cells)	-	2009/05/14	2017/02/23	-	rogid:5yFpm82AhZnBT5toA6FfcvVKS3E10090	intact-crc:8F0BD6F7C3248434	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000020826	uniprotkb:Q04207	intact:EBI-2337397	intact:EBI-644400|uniprotkb:Q62025|ensembl:ENSMUSP00000025867	psi-mi:inos_mouse_gene(display_short)|psi-mi:ENSMUSG00000020826(display_long)	psi-mi:tf65_mouse(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:Nfkb3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337488|imex:IM-12171-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_033071.1|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5621575|reactome:R-MMU-9020702|reactome:R-MMU-933542|rcsb pdb:2RAM|rcsb pdb:5U01|rcsb pdb:6GGR|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|ensembl:ENSMUSG00000024927(gene)|ensembl:ENSMUST00000025867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|mint:Q04207|rcsb pdb:1BFT|rcsb pdb:1IKN|rcsb pdb:1K3Z|rcsb pdb:1LE5|rcsb pdb:1LE9|rcsb pdb:1LEI|rcsb pdb:1MY5|rcsb pdb:1MY7|rcsb pdb:1OY3|rcsb pdb:1RAM|interpro:IPR037059|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2LWW|dip:DIP-6219N	-	-	-	figure legend:Figs. 4F|agonist:Lipopolysaccharide|comment:Binding is to the promoter region of the gene.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-bv2)|taxid:10090(Mouse BV2 glioma cells)	-	2009/05/14	2014/10/16	-	rogid:poiJSPJwXK2Om5pfk8z5HwFgK1o10090	intact-crc:CC21E93D92124595	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000024401	uniprotkb:Q8CFE3	intact:EBI-2337474	intact:EBI-2337309|uniprotkb:Q3V092|uniprotkb:Q8BK28|uniprotkb:Q8CHI2|uniprotkb:K3W4P9|ensembl:ENSMUSP00000082034	psi-mi:tnfa_mouse_gene(display_short)|psi-mi:ENSMUSG00000024401(display_long)	psi-mi:rcor1_mouse(display_long)|uniprotkb:Rcor1(gene name)|psi-mi:Rcor1(display_short)|uniprotkb:D12Wsu95e(gene name synonym)|uniprotkb:Kiaa0071(gene name synonym)|uniprotkb:Protein CoREST(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337533|imex:IM-12171-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:XP_006515823.1|dip:DIP-48899N|refseq:NP_932140.1|ensembl:ENSMUSG00000037896(gene)|ensembl:ENSMUST00000084968(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1990391"(DNA repair complex)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q8CFE3|reactome:R-MMU-3214815|reactome:R-MMU-983231	-	-	-	figure legend:Figs. 4H, Supp. Fig. 9C|agonist:Lipopolysaccharide|comment:Recruitment requires the presence of Nr4A2. Binding is to the promoter region of the gene.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-bv2)|taxid:10090(Mouse BV2 glioma cells)	-	2009/05/14	2017/02/23	-	rogid:5yFpm82AhZnBT5toA6FfcvVKS3E10090	intact-crc:20126C2B1EED8E8B	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000024401	uniprotkb:Q04207	intact:EBI-2337474	intact:EBI-644400|uniprotkb:Q62025|ensembl:ENSMUSP00000025867	psi-mi:tnfa_mouse_gene(display_short)|psi-mi:ENSMUSG00000024401(display_long)	psi-mi:tf65_mouse(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:Nfkb3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337540|imex:IM-12171-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_033071.1|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5621575|reactome:R-MMU-9020702|reactome:R-MMU-933542|rcsb pdb:2RAM|rcsb pdb:5U01|rcsb pdb:6GGR|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|ensembl:ENSMUSG00000024927(gene)|ensembl:ENSMUST00000025867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|mint:Q04207|rcsb pdb:1BFT|rcsb pdb:1IKN|rcsb pdb:1K3Z|rcsb pdb:1LE5|rcsb pdb:1LE9|rcsb pdb:1LEI|rcsb pdb:1MY5|rcsb pdb:1MY7|rcsb pdb:1OY3|rcsb pdb:1RAM|interpro:IPR037059|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2LWW|dip:DIP-6219N	-	-	-	figure legend:Figs. 4H, Supp. Fig. 9C|agonist:Lipopolysaccharide|comment:Recruitment does not require the presence of NR4A2. Binding is to the promoter region of the gene.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-bv2)|taxid:10090(Mouse BV2 glioma cells)	-	2009/05/14	2014/10/16	-	rogid:poiJSPJwXK2Om5pfk8z5HwFgK1o10090	intact-crc:8A33AE1CD306B81D	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q04207	uniprotkb:Q06219	intact:EBI-644400|uniprotkb:Q62025|ensembl:ENSMUSP00000025867	intact:EBI-2337255|uniprotkb:O08690|ensembl:ENSMUSP00000028166|ensembl:ENSMUSP00000108248	psi-mi:tf65_mouse(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:Nfkb3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	psi-mi:nr4a2_mouse(display_long)|uniprotkb:Nr4a2(gene name)|psi-mi:Nr4a2(display_short)|uniprotkb:Nurr1(gene name synonym)|uniprotkb:Orphan nuclear receptor NURR1(gene name synonym)|uniprotkb:NUR-related factor 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337609|imex:IM-12171-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033071.1|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5621575|reactome:R-MMU-9020702|reactome:R-MMU-933542|rcsb pdb:2RAM|rcsb pdb:5U01|rcsb pdb:6GGR|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|ensembl:ENSMUSG00000024927(gene)|ensembl:ENSMUST00000025867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|mint:Q04207|rcsb pdb:1BFT|rcsb pdb:1IKN|rcsb pdb:1K3Z|rcsb pdb:1LE5|rcsb pdb:1LE9|rcsb pdb:1LEI|rcsb pdb:1MY5|rcsb pdb:1MY7|rcsb pdb:1OY3|rcsb pdb:1RAM|interpro:IPR037059|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2LWW|dip:DIP-6219N	refseq:XP_011237335.1|refseq:XP_011237336.1|refseq:NP_001132981.1|refseq:NP_038641.1|ensembl:ENSMUSG00000026826(gene)|ensembl:ENSMUST00000028166(transcript)|ensembl:ENSMUST00000112629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017085"(response to insecticide)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0021986"(habenula development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042551"(neuron maturation)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043576"(regulation of respiratory gaseous exchange)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051866"(general adaptation syndrome)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003073(Orphan nuclear receptor, NURR type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 6A|agonist:IL-1beta|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-astrocyte)|taxid:10090(Mus musculus astrocyte [Brain astrocytes; Astroglia])	-	2009/05/14	2014/10/16	rogid:poiJSPJwXK2Om5pfk8z5HwFgK1o10090	rogid:CK0Kua7DlmmUoBPZe0SdkqHeg9s10090	intact-crc:9B86B6EEBBE2AE7B|rigid:DL2pBYbshuH8YENa5ROE/xJNB9c	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q06219	uniprotkb:Q8CFE3	intact:EBI-2337255|uniprotkb:O08690|ensembl:ENSMUSP00000028166|ensembl:ENSMUSP00000108248	intact:EBI-2337309|uniprotkb:Q3V092|uniprotkb:Q8BK28|uniprotkb:Q8CHI2|uniprotkb:K3W4P9|ensembl:ENSMUSP00000082034	psi-mi:nr4a2_mouse(display_long)|uniprotkb:Nr4a2(gene name)|psi-mi:Nr4a2(display_short)|uniprotkb:Nurr1(gene name synonym)|uniprotkb:Orphan nuclear receptor NURR1(gene name synonym)|uniprotkb:NUR-related factor 1(gene name synonym)	psi-mi:rcor1_mouse(display_long)|uniprotkb:Rcor1(gene name)|psi-mi:Rcor1(display_short)|uniprotkb:D12Wsu95e(gene name synonym)|uniprotkb:Kiaa0071(gene name synonym)|uniprotkb:Protein CoREST(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337628|imex:IM-12171-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011237335.1|refseq:XP_011237336.1|refseq:NP_001132981.1|refseq:NP_038641.1|ensembl:ENSMUSG00000026826(gene)|ensembl:ENSMUST00000028166(transcript)|ensembl:ENSMUST00000112629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017085"(response to insecticide)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0021986"(habenula development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042551"(neuron maturation)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043576"(regulation of respiratory gaseous exchange)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051866"(general adaptation syndrome)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003073(Orphan nuclear receptor, NURR type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280	refseq:XP_006515823.1|dip:DIP-48899N|refseq:NP_932140.1|ensembl:ENSMUSG00000037896(gene)|ensembl:ENSMUST00000084968(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1990391"(DNA repair complex)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q8CFE3|reactome:R-MMU-3214815|reactome:R-MMU-983231	psi-mi:"MI:0469"(intact)	-	-	figure legend:Figs. 4B, 4E|agonist:Lipopolysaccharide|comment:Nr4a2-Rcor1 interaction was significantly reduced by NLK-knockdown in BV2 cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-astrocyte)|taxid:10090(Mus musculus astrocyte [Brain astrocytes; Astroglia])	-	2009/05/14	2017/02/23	rogid:CK0Kua7DlmmUoBPZe0SdkqHeg9s10090	rogid:5yFpm82AhZnBT5toA6FfcvVKS3E10090	intact-crc:722A472A3FBAB77A|rigid:oCVXNeZZik00p8sErejlYuBjDic	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q06219	ensembl:ENSMUSG00000020826	intact:EBI-2337255|uniprotkb:O08690|ensembl:ENSMUSP00000028166|ensembl:ENSMUSP00000108248	intact:EBI-2337397	psi-mi:nr4a2_mouse(display_long)|uniprotkb:Nr4a2(gene name)|psi-mi:Nr4a2(display_short)|uniprotkb:Nurr1(gene name synonym)|uniprotkb:Orphan nuclear receptor NURR1(gene name synonym)|uniprotkb:NUR-related factor 1(gene name synonym)	psi-mi:inos_mouse_gene(display_short)|psi-mi:ENSMUSG00000020826(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337615|imex:IM-12171-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:XP_011237335.1|refseq:XP_011237336.1|refseq:NP_001132981.1|refseq:NP_038641.1|ensembl:ENSMUSG00000026826(gene)|ensembl:ENSMUST00000028166(transcript)|ensembl:ENSMUST00000112629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017085"(response to insecticide)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0021986"(habenula development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042551"(neuron maturation)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043576"(regulation of respiratory gaseous exchange)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051866"(general adaptation syndrome)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003073(Orphan nuclear receptor, NURR type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280	-	-	-	-	figure legend:Figs. 6B, 6C|antagonist:"GSK3B-specific inhibitor SB216763 (SB21)"|agonist:IL-1beta|comment:Binding was to the promoter region of the gene.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-astrocyte)|taxid:10090(Mus musculus astrocyte [Brain astrocytes; Astroglia])	-	2009/05/14	2014/10/16	rogid:CK0Kua7DlmmUoBPZe0SdkqHeg9s10090	-	intact-crc:417EFB06EB1A9B45	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q04207	ensembl:ENSMUSG00000020826	intact:EBI-644400|uniprotkb:Q62025|ensembl:ENSMUSP00000025867	intact:EBI-2337397	psi-mi:tf65_mouse(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:Nfkb3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	psi-mi:inos_mouse_gene(display_short)|psi-mi:ENSMUSG00000020826(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337621|imex:IM-12171-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_033071.1|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5621575|reactome:R-MMU-9020702|reactome:R-MMU-933542|rcsb pdb:2RAM|rcsb pdb:5U01|rcsb pdb:6GGR|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|ensembl:ENSMUSG00000024927(gene)|ensembl:ENSMUST00000025867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|mint:Q04207|rcsb pdb:1BFT|rcsb pdb:1IKN|rcsb pdb:1K3Z|rcsb pdb:1LE5|rcsb pdb:1LE9|rcsb pdb:1LEI|rcsb pdb:1MY5|rcsb pdb:1MY7|rcsb pdb:1OY3|rcsb pdb:1RAM|interpro:IPR037059|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2LWW|dip:DIP-6219N	-	-	-	-	figure legend:Figs. 6B|agonist:IL-1beta|comment:Binding was to the promoter region of the gene.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-astrocyte)|taxid:10090(Mus musculus astrocyte [Brain astrocytes; Astroglia])	-	2009/05/14	2014/10/16	rogid:poiJSPJwXK2Om5pfk8z5HwFgK1o10090	-	intact-crc:8F8CD1AB56762292	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q8CFE3	ensembl:ENSMUSG00000020826	intact:EBI-2337309|uniprotkb:Q3V092|uniprotkb:Q8BK28|uniprotkb:Q8CHI2|uniprotkb:K3W4P9|ensembl:ENSMUSP00000082034	intact:EBI-2337397	psi-mi:rcor1_mouse(display_long)|uniprotkb:Rcor1(gene name)|psi-mi:Rcor1(display_short)|uniprotkb:D12Wsu95e(gene name synonym)|uniprotkb:Kiaa0071(gene name synonym)|uniprotkb:Protein CoREST(gene name synonym)	psi-mi:inos_mouse_gene(display_short)|psi-mi:ENSMUSG00000020826(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337635|imex:IM-12171-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:XP_006515823.1|dip:DIP-48899N|refseq:NP_932140.1|ensembl:ENSMUSG00000037896(gene)|ensembl:ENSMUST00000084968(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1990391"(DNA repair complex)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q8CFE3|reactome:R-MMU-3214815|reactome:R-MMU-983231	-	-	-	-	figure legend:Figs. 6E|agonist:IL-1B|comment:Binding was to the promoter region of the gene.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-astrocyte)|taxid:10090(Mus musculus astrocyte [Brain astrocytes; Astroglia])	-	2009/05/14	2017/02/23	rogid:5yFpm82AhZnBT5toA6FfcvVKS3E10090	-	intact-crc:EF628E411084CB17	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q8CFE3	uniprotkb:Q06219	intact:EBI-2337309|uniprotkb:Q3V092|uniprotkb:Q8BK28|uniprotkb:Q8CHI2|uniprotkb:K3W4P9|ensembl:ENSMUSP00000082034	intact:EBI-2337255|uniprotkb:O08690|ensembl:ENSMUSP00000028166|ensembl:ENSMUSP00000108248	psi-mi:rcor1_mouse(display_long)|uniprotkb:Rcor1(gene name)|psi-mi:Rcor1(display_short)|uniprotkb:D12Wsu95e(gene name synonym)|uniprotkb:Kiaa0071(gene name synonym)|uniprotkb:Protein CoREST(gene name synonym)	psi-mi:nr4a2_mouse(display_long)|uniprotkb:Nr4a2(gene name)|psi-mi:Nr4a2(display_short)|uniprotkb:Nurr1(gene name synonym)|uniprotkb:Orphan nuclear receptor NURR1(gene name synonym)|uniprotkb:NUR-related factor 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337647|imex:IM-12171-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006515823.1|dip:DIP-48899N|refseq:NP_932140.1|ensembl:ENSMUSG00000037896(gene)|ensembl:ENSMUST00000084968(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1990391"(DNA repair complex)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q8CFE3|reactome:R-MMU-3214815|reactome:R-MMU-983231	refseq:XP_011237335.1|refseq:XP_011237336.1|refseq:NP_001132981.1|refseq:NP_038641.1|ensembl:ENSMUSG00000026826(gene)|ensembl:ENSMUST00000028166(transcript)|ensembl:ENSMUST00000112629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017085"(response to insecticide)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0021986"(habenula development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042551"(neuron maturation)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043576"(regulation of respiratory gaseous exchange)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051866"(general adaptation syndrome)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003073(Orphan nuclear receptor, NURR type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280	psi-mi:"MI:0469"(intact)	-	-	figure legend:Supp. Fig. 8C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/14	2017/02/23	rogid:5yFpm82AhZnBT5toA6FfcvVKS3E10090	rogid:CK0Kua7DlmmUoBPZe0SdkqHeg9s10090	intact-crc:41E9ED2DEF5A27A6|rigid:oCVXNeZZik00p8sErejlYuBjDic	false	35s radiolabel:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q06219	uniprotkb:Q8CFE3	intact:EBI-2337255|uniprotkb:O08690|ensembl:ENSMUSP00000028166|ensembl:ENSMUSP00000108248	intact:EBI-2337309|uniprotkb:Q3V092|uniprotkb:Q8BK28|uniprotkb:Q8CHI2|uniprotkb:K3W4P9|ensembl:ENSMUSP00000082034	psi-mi:nr4a2_mouse(display_long)|uniprotkb:Nr4a2(gene name)|psi-mi:Nr4a2(display_short)|uniprotkb:Nurr1(gene name synonym)|uniprotkb:Orphan nuclear receptor NURR1(gene name synonym)|uniprotkb:NUR-related factor 1(gene name synonym)	psi-mi:rcor1_mouse(display_long)|uniprotkb:Rcor1(gene name)|psi-mi:Rcor1(display_short)|uniprotkb:D12Wsu95e(gene name synonym)|uniprotkb:Kiaa0071(gene name synonym)|uniprotkb:Protein CoREST(gene name synonym)	psi-mi:"MI:0096"(pull down)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337658|imex:IM-12171-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011237335.1|refseq:XP_011237336.1|refseq:NP_001132981.1|refseq:NP_038641.1|ensembl:ENSMUSG00000026826(gene)|ensembl:ENSMUST00000028166(transcript)|ensembl:ENSMUST00000112629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017085"(response to insecticide)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0021986"(habenula development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042551"(neuron maturation)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043576"(regulation of respiratory gaseous exchange)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051866"(general adaptation syndrome)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003073(Orphan nuclear receptor, NURR type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280	refseq:XP_006515823.1|dip:DIP-48899N|refseq:NP_932140.1|ensembl:ENSMUSG00000037896(gene)|ensembl:ENSMUST00000084968(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1990391"(DNA repair complex)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q8CFE3|reactome:R-MMU-3214815|reactome:R-MMU-983231	psi-mi:"MI:0469"(intact)	-	-	figure legend:Supp. Fig. 8C, 8D|caution:DNA binding region of MR4A2 not given in paper and has been inferred from the UniProt entry.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/05/14	2017/02/23	rogid:CK0Kua7DlmmUoBPZe0SdkqHeg9s10090	rogid:5yFpm82AhZnBT5toA6FfcvVKS3E10090	intact-crc:B0187F66769BF761|rigid:oCVXNeZZik00p8sErejlYuBjDic	false	35s radiolabel:?-?|sufficient binding region:263..263-323..323	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q8CFE3	uniprotkb:Q06219	intact:EBI-2337309|uniprotkb:Q3V092|uniprotkb:Q8BK28|uniprotkb:Q8CHI2|uniprotkb:K3W4P9|ensembl:ENSMUSP00000082034	intact:EBI-2337255|uniprotkb:O08690|ensembl:ENSMUSP00000028166|ensembl:ENSMUSP00000108248	psi-mi:rcor1_mouse(display_long)|uniprotkb:Rcor1(gene name)|psi-mi:Rcor1(display_short)|uniprotkb:D12Wsu95e(gene name synonym)|uniprotkb:Kiaa0071(gene name synonym)|uniprotkb:Protein CoREST(gene name synonym)	psi-mi:nr4a2_mouse(display_long)|uniprotkb:Nr4a2(gene name)|psi-mi:Nr4a2(display_short)|uniprotkb:Nurr1(gene name synonym)|uniprotkb:Orphan nuclear receptor NURR1(gene name synonym)|uniprotkb:NUR-related factor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337676|imex:IM-12171-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006515823.1|dip:DIP-48899N|refseq:NP_932140.1|ensembl:ENSMUSG00000037896(gene)|ensembl:ENSMUST00000084968(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1990391"(DNA repair complex)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q8CFE3|reactome:R-MMU-3214815|reactome:R-MMU-983231	refseq:XP_011237335.1|refseq:XP_011237336.1|refseq:NP_001132981.1|refseq:NP_038641.1|ensembl:ENSMUSG00000026826(gene)|ensembl:ENSMUST00000028166(transcript)|ensembl:ENSMUST00000112629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017085"(response to insecticide)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0021986"(habenula development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042551"(neuron maturation)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043576"(regulation of respiratory gaseous exchange)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051866"(general adaptation syndrome)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003073(Orphan nuclear receptor, NURR type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280	psi-mi:"MI:0469"(intact)	-	-	figure legend:Supp. Fig. 8F|caution:DNA binding region of MR4A2 not given in paper and has been inferred from the UniProt entry.|comment:"When Nr4a2-DBD was overexpressed, the interaction between Nr4a2 and Rcor1 was inhibited in a dose-dependent manner (Figure S8F)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2009/05/14	2017/02/23	rogid:5yFpm82AhZnBT5toA6FfcvVKS3E10090	rogid:CK0Kua7DlmmUoBPZe0SdkqHeg9s10090	intact-crc:FCB3E9B28CBF9FBE|rigid:oCVXNeZZik00p8sErejlYuBjDic	false	ha tag:?-?	sufficient binding region:263..263-323..323|myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8CFE3	uniprotkb:Q06219	intact:EBI-2337309|uniprotkb:Q3V092|uniprotkb:Q8BK28|uniprotkb:Q8CHI2|uniprotkb:K3W4P9|ensembl:ENSMUSP00000082034	intact:EBI-2337255|uniprotkb:O08690|ensembl:ENSMUSP00000028166|ensembl:ENSMUSP00000108248	psi-mi:rcor1_mouse(display_long)|uniprotkb:Rcor1(gene name)|psi-mi:Rcor1(display_short)|uniprotkb:D12Wsu95e(gene name synonym)|uniprotkb:Kiaa0071(gene name synonym)|uniprotkb:Protein CoREST(gene name synonym)	psi-mi:nr4a2_mouse(display_long)|uniprotkb:Nr4a2(gene name)|psi-mi:Nr4a2(display_short)|uniprotkb:Nurr1(gene name synonym)|uniprotkb:Orphan nuclear receptor NURR1(gene name synonym)|uniprotkb:NUR-related factor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Saijo et al. (2009)	imex:IM-12171|pubmed:19345186	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2337676|imex:IM-12171-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006515823.1|dip:DIP-48899N|refseq:NP_932140.1|ensembl:ENSMUSG00000037896(gene)|ensembl:ENSMUST00000084968(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1990391"(DNA repair complex)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q8CFE3|reactome:R-MMU-3214815|reactome:R-MMU-983231	refseq:XP_011237335.1|refseq:XP_011237336.1|refseq:NP_001132981.1|refseq:NP_038641.1|ensembl:ENSMUSG00000026826(gene)|ensembl:ENSMUST00000028166(transcript)|ensembl:ENSMUST00000112629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017085"(response to insecticide)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0021986"(habenula development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042551"(neuron maturation)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043576"(regulation of respiratory gaseous exchange)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051866"(general adaptation syndrome)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003073(Orphan nuclear receptor, NURR type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280	psi-mi:"MI:0469"(intact)	-	-	figure legend:Supp. Fig. 8F|caution:DNA binding region of MR4A2 not given in paper and has been inferred from the UniProt entry.|comment:"When Nr4a2-DBD was overexpressed, the interaction between Nr4a2 and Rcor1 was inhibited in a dose-dependent manner (Figure S8F)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2009/05/14	2017/02/23	rogid:5yFpm82AhZnBT5toA6FfcvVKS3E10090	rogid:CK0Kua7DlmmUoBPZe0SdkqHeg9s10090	intact-crc:FCB3E9B28CBF9FBE|rigid:oCVXNeZZik00p8sErejlYuBjDic	false	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)