#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P61764	uniprotkb:Q13393	intact:EBI-960169|uniprotkb:Q28208|uniprotkb:Q62759|uniprotkb:Q64320|uniprotkb:Q96TG8|uniprotkb:B1AM97|uniprotkb:Q68CM6|ensembl:ENSP00000362396	intact:EBI-2827556|ensembl:ENSP00000342793	psi-mi:stxb1_human(display_long)|uniprotkb:STXBP1(gene name)|psi-mi:STXBP1(display_short)|uniprotkb:UNC18A(gene name synonym)|uniprotkb:Protein unc-18 homolog 1(gene name synonym)|uniprotkb:Protein unc-18 homolog A(gene name synonym)|uniprotkb:N-Sec1(gene name synonym)|uniprotkb:p67(gene name synonym)|uniprotkb:MUNC18-1(gene name synonym)	psi-mi:pld1_human(display_long)|uniprotkb:PLD1(gene name)|psi-mi:PLD1(display_short)|uniprotkb:Choline phosphatase 1(gene name synonym)|uniprotkb:Phosphatidylcholine-hydrolyzing phospholipase D1(gene name synonym)	psi-mi:"MI:0872"(atomic force microscopy)	Kim et al. (2009)	pubmed:19323535|mint:MINT-7215275|doi:10.1021/ac8024366	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-6941067|mint:MINT-7231494	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001027392.1|refseq:NP_003156.1|ensembl:ENSG00000136854(gene)|ensembl:ENST00000373299(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0002576"(platelet degranulation)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0005739"(mitochondrion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007412"(axon target recognition)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030424"(axon)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031630"(regulation of synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032229"(negative regulation of synaptic transmission, GABAergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:0106022"(positive regulation of vesicle docking)|go:"GO:1903296"(positive regulation of glutamate secretion, neurotransmission)|go:"GO:2000367"(regulation of acrosomal vesicle exocytosis)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|mint:P61764|rcsb pdb:6L03|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-422356|reactome:R-HSA-6794361|reactome:R-HSA-888590|mint:MINT-7231497(identity)	refseq:XP_011511199.1|refseq:NP_002653.1|ensembl:ENSG00000075651(gene)|ensembl:ENST00000351298(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004630"(phospholipase D activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048870"(cell motility)|go:"GO:0070290"(N-acylphosphatidylethanolamine-specific phospholipase D activity)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098981"(cholinergic synapse)|interpro:IPR001683(Phox-like)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015679(Phospholipase D)|interpro:IPR016555(Phospholipase D, eukaryota)|interpro:IPR025202|interpro:IPR036871|mint:Q13393|rcsb pdb:6U8Z|reactome:R-HSA-1483148|reactome:R-HSA-1483166|reactome:R-HSA-2029485|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|refseq:XP_005247590.1|refseq:XP_005247591.1|dip:DIP-40821N|mint:MINT-7231496(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f2 f3|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/07/22	2014/10/16	rogid:yUYi89hDkfMdQ1BdH52swZQFCLk9606	rogid:4TlTbVJTGGyEAcq/Gby1STgUH4Q9606	intact-crc:F2F9C758DA8F9D41|rigid:mO6F5GGXAmBMy89SGMZxNYCSS3c	false	-	binding-associated region:81-211(MINT-7231503)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13393	uniprotkb:P19174	intact:EBI-2827556|ensembl:ENSP00000342793	intact:EBI-79387|uniprotkb:Q2V575|uniprotkb:B9EGH4|uniprotkb:B7ZLY7|uniprotkb:E1P5W4|intact:EBI-3959906|ensembl:ENSP00000362368	psi-mi:pld1_human(display_long)|uniprotkb:PLD1(gene name)|psi-mi:PLD1(display_short)|uniprotkb:Choline phosphatase 1(gene name synonym)|uniprotkb:Phosphatidylcholine-hydrolyzing phospholipase D1(gene name synonym)	psi-mi:plcg1_human(display_long)|uniprotkb:PLC-148(gene name synonym)|uniprotkb:PLC1(gene name synonym)|uniprotkb:Phospholipase C-II(gene name synonym)|uniprotkb:PLCG1(gene name)|psi-mi:PLCG1(display_short)|uniprotkb:Phosphoinositide phospholipase C-gamma-1(gene name synonym)|uniprotkb:Phospholipase C-gamma-1(gene name synonym)	psi-mi:"MI:0872"(atomic force microscopy)	Kim et al. (2009)	pubmed:19323535|mint:MINT-7215275|doi:10.1021/ac8024366	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-6941115|mint:MINT-7231507	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011511199.1|refseq:NP_002653.1|ensembl:ENSG00000075651(gene)|ensembl:ENST00000351298(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004630"(phospholipase D activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048870"(cell motility)|go:"GO:0070290"(N-acylphosphatidylethanolamine-specific phospholipase D activity)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098981"(cholinergic synapse)|interpro:IPR001683(Phox-like)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015679(Phospholipase D)|interpro:IPR016555(Phospholipase D, eukaryota)|interpro:IPR025202|interpro:IPR036871|mint:Q13393|rcsb pdb:6U8Z|reactome:R-HSA-1483148|reactome:R-HSA-1483166|reactome:R-HSA-2029485|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|refseq:XP_005247590.1|refseq:XP_005247591.1|dip:DIP-40821N|mint:MINT-7231511(identity)	refseq:NP_002651.2|refseq:NP_877963.1|dip:DIP-100N|ensembl:ENSG00000124181(gene)|ensembl:ENST00000373271(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001726"(ruffle)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042995"(cell projection)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0050429"(calcium-dependent phospholipase C activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR000980(SH2 motif)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001452(Src homology-3)|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016279(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma)|interpro:IPR017946|interpro:IPR018247|interpro:IPR028380|interpro:IPR035023|interpro:IPR035024|interpro:IPR035724|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|mint:P19174|rcsb pdb:1HSQ|rcsb pdb:2HSP|rcsb pdb:4EY0|rcsb pdb:4FBN|rcsb pdb:7NXE|reactome:R-HSA-1169408|reactome:R-HSA-1236382|reactome:R-HSA-1251932|reactome:R-HSA-1489509|reactome:R-HSA-167021|reactome:R-HSA-1855204|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029485|reactome:R-HSA-210990|reactome:R-HSA-212718|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-418890|reactome:R-HSA-5218921|reactome:R-HSA-5637810|reactome:R-HSA-5654219|reactome:R-HSA-5654221|reactome:R-HSA-5654227|reactome:R-HSA-5654228|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-9026527|reactome:R-HSA-9027277|reactome:R-HSA-9034793|reactome:R-HSA-9664323|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|mint:MINT-7231509(identity)	-	-	-	figure legend:f4|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/07/22	2014/10/16	rogid:4TlTbVJTGGyEAcq/Gby1STgUH4Q9606	rogid:pJsNLrqg3cUj0SdjoyLf+/91yBo9606	intact-crc:7C060A618AC3F7CC|rigid:gbqlc6KdaMjaEPyPjkYW7RJckd4	false	binding-associated region:81-211(MINT-7231512)	binding-associated region:791-851(MINT-7231518)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)