#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q6UEA7	uniprotkb:Q5KLS3	intact:EBI-6935830|intact:MINT-7261007	intact:EBI-11811581|uniprotkb:Q55Y65|ensemblfungi:AAW41941	psi-mi:q6uea7_crynv(display_long)	psi-mi:q5kls3_crynj(display_long)|uniprotkb:CNB04250(locus name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Hsueh et al. (2009)	pubmed:19322200|imex:IM-13819|mint:MINT-7260980|doi:10.1038/emboj.2009.68	taxid:178876(crynv)|taxid:178876(Cryptococcus neoformans var. grubii)	taxid:214684(crynj)|taxid:214684("Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6935877|mint:MINT-7261015|imex:IM-13819-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0019001"(guanyl nucleotide binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR027417|interpro:IPR000469(G-protein alpha subunit, group 12)|interpro:IPR011025(G protein alpha subunit, helical insertion)|mint:Q6UEA7|mint:MINT-7261018(identity)	interpro:IPR001499(Fungal pheromone STE3 GPCR)|refseq:XP_569248.1|mint:Q5KLS3|ensemblfungi:AAW41941(transcript)|ensemblfungi:CNB04250(gene)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000755"(cytogamy)|go:"GO:0004932"(mating-type factor pheromone receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|mint:MINT-7261017(identity)	-	comment:mint	-	figure legend:f5b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/09/01	2016/07/08	rogid:NvzFC6eg6fIEHsqd99RD2B/P040178876	rogid:VabwZ2oXeqYieIPxraxepOtuEaA214684	intact-crc:EED92B7DA8F54928|rigid:DFc9EB9ht9Zi4ROJcyWIkVPikvg	false	fusion protein:?-?(MINT-7261020)	fusion protein:?-?(MINT-7261024)|mutation increasing interaction:222-222(MINT-7261027)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0CP78	uniprotkb:P0CP78	intact:EBI-6935844|ensemblfungi:AAW44558|intact:MINT-7260990|uniprotkb:Q55P39|uniprotkb:Q5KEB7	intact:EBI-6935844|ensemblfungi:AAW44558|intact:MINT-7260990|uniprotkb:Q55P39|uniprotkb:Q5KEB7	psi-mi:ppib_crynj(display_long)|uniprotkb:CPR2(gene name)|psi-mi:CPR2(display_short)|uniprotkb:Rotamase B(gene name synonym)|uniprotkb:CNG01060(locus name)	psi-mi:ppib_crynj(display_long)|uniprotkb:CPR2(gene name)|psi-mi:CPR2(display_short)|uniprotkb:Rotamase B(gene name synonym)|uniprotkb:CNG01060(locus name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Hsueh et al. (2009)	pubmed:19322200|imex:IM-13819|mint:MINT-7260980|doi:10.1038/emboj.2009.68	taxid:214684(crynj)|taxid:214684("Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)")	taxid:214684(crynj)|taxid:214684("Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6936025|mint:MINT-7261055|imex:IM-13819-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:AAW44558(transcript)|ensemblfungi:CNG01060(gene)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|refseq:XP_571865.1|interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR029000|mint:P0CP78|mint:MINT-7261061(identity)	ensemblfungi:AAW44558(transcript)|ensemblfungi:CNG01060(gene)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|refseq:XP_571865.1|interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR029000|mint:P0CP78|mint:MINT-7261057(identity)	-	comment:mint	comment:mint	figure legend:f5b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/09/01	2014/10/16	rogid:zhlVqNMb+FU8fqAt+tPiOji/tV8214684	rogid:zhlVqNMb+FU8fqAt+tPiOji/tV8214684	intact-crc:A45F495974487C23|rigid:58aKbevpzlxFoHA/0jTVmTVr/4Q	false	fusion protein:?-?(MINT-7261062)	fusion protein:?-?(MINT-7261058)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0CP78	uniprotkb:Q69FA9	intact:EBI-6935844|ensemblfungi:AAW44558|intact:MINT-7260990|uniprotkb:Q55P39|uniprotkb:Q5KEB7	intact:EBI-6935980|intact:MINT-7261046	psi-mi:ppib_crynj(display_long)|uniprotkb:CPR2(gene name)|psi-mi:CPR2(display_short)|uniprotkb:Rotamase B(gene name synonym)|uniprotkb:CNG01060(locus name)	psi-mi:q69fa9_cryne(display_long)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Hsueh et al. (2009)	pubmed:19322200|imex:IM-13819|mint:MINT-7260980|doi:10.1038/emboj.2009.68	taxid:214684(crynj)|taxid:214684("Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)")	taxid:40410(cryptococcus neoformans var. neoformans)|taxid:40410(Cryptococcus neoformans var. neoformans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6935992|mint:MINT-7261031|imex:IM-13819-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:AAW44558(transcript)|ensemblfungi:CNG01060(gene)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|refseq:XP_571865.1|interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR029000|mint:P0CP78|mint:MINT-7261037(identity)	go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR016137(Regulator of G protein signalling superfamily)|mint:Q69FA9|interpro:IPR036305|interpro:IPR036388|interpro:IPR036390|mint:MINT-7261033(identity)	-	comment:mint	comment:mint	figure legend:f5b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/09/01	2014/10/16	rogid:zhlVqNMb+FU8fqAt+tPiOji/tV8214684	rogid:y8oHbUwZVqDFmlZ35MJ6lRef9pE40410	intact-crc:C8CAA76C3111AD5D|rigid:O7FaHLtt7/H1b6x0YNV/hTi8LhM	false	fusion protein:?-?(MINT-7261040)	fusion protein:?-?(MINT-7261034)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0CP78	uniprotkb:Q8J0X5	intact:EBI-6935844|ensemblfungi:AAW44558|intact:MINT-7260990|uniprotkb:Q55P39|uniprotkb:Q5KEB7	intact:EBI-6936174|intact:MINT-7261112	psi-mi:ppib_crynj(display_long)|uniprotkb:CPR2(gene name)|psi-mi:CPR2(display_short)|uniprotkb:Rotamase B(gene name synonym)|uniprotkb:CNG01060(locus name)	psi-mi:q8j0x5_cryne(display_long)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Hsueh et al. (2009)	pubmed:19322200|imex:IM-13819|mint:MINT-7260980|doi:10.1038/emboj.2009.68	taxid:214684(crynj)|taxid:214684("Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)")	taxid:40410(cryptococcus neoformans var. neoformans)|taxid:40410(Cryptococcus neoformans var. neoformans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6936169|mint:MINT-7261101|imex:IM-13819-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:AAW44558(transcript)|ensemblfungi:CNG01060(gene)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|refseq:XP_571865.1|interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR029000|mint:P0CP78|mint:MINT-7261107(identity)	go:"GO:0004933"(mating-type a-factor pheromone receptor activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001499(Fungal pheromone STE3 GPCR)|interpro:IPR001546(Pheromone A receptor)|mint:Q8J0X5|mint:MINT-7261103(identity)	-	comment:mint	comment:mint	figure legend:f5b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/09/01	2014/10/16	rogid:zhlVqNMb+FU8fqAt+tPiOji/tV8214684	rogid:87O9IXxg+pe/tx/ART8y/w9es1U40410	intact-crc:474144DF5DB407AF|rigid:QcOERsHXEkbfUWB4Q/so8futIVY	false	fusion protein:?-?(MINT-7261108)	fusion protein:?-?(MINT-7261104)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0CP78	uniprotkb:Q5KHP2	intact:EBI-6935844|ensemblfungi:AAW44558|intact:MINT-7260990|uniprotkb:Q55P39|uniprotkb:Q5KEB7	intact:EBI-6936099|ensemblfungi:AAW42809|uniprotkb:Q55UP9|intact:MINT-7261078	psi-mi:ppib_crynj(display_long)|uniprotkb:CPR2(gene name)|psi-mi:CPR2(display_short)|uniprotkb:Rotamase B(gene name synonym)|uniprotkb:CNG01060(locus name)	psi-mi:q5khp2_crynj(display_long)|uniprotkb:CND05800(locus name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Hsueh et al. (2009)	pubmed:19322200|imex:IM-13819|mint:MINT-7260980|doi:10.1038/emboj.2009.68	taxid:214684(crynj)|taxid:214684("Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)")	taxid:214684(crynj)|taxid:214684("Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6936111|mint:MINT-7261067|imex:IM-13819-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:AAW44558(transcript)|ensemblfungi:CNG01060(gene)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|refseq:XP_571865.1|interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR029000|mint:P0CP78|mint:MINT-7261073(identity)	ensemblfungi:AAW42809(transcript)|ensemblfungi:CND05800(gene)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000755"(cytogamy)|go:"GO:0004932"(mating-type factor pheromone receptor activity)|go:"GO:0004933"(mating-type a-factor pheromone receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|refseq:XP_570116.1|interpro:IPR001499(Fungal pheromone STE3 GPCR)|interpro:IPR001546(Pheromone A receptor)|mint:Q5KHP2|mint:MINT-7261069(identity)	-	comment:mint	comment:mint	figure legend:f5b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/09/01	2014/10/16	rogid:zhlVqNMb+FU8fqAt+tPiOji/tV8214684	rogid:SYKJ2aN/RUvuDkwUhJ8riGAvnI4214684	intact-crc:236640CC96C84CDB|rigid:pOhj0PjMoYkBjcqWTWhOJ0IlwQM	false	fusion protein:?-?(MINT-7261074)	fusion protein:?-?(MINT-7261070)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10823	uniprotkb:Q5KLS3	intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W	intact:EBI-11811581|uniprotkb:Q55Y65|ensemblfungi:AAW41941	psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym)	psi-mi:q5kls3_crynj(display_long)|uniprotkb:CNB04250(locus name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Hsueh et al. (2009)	pubmed:19322200|imex:IM-13819|mint:MINT-7260980|doi:10.1038/emboj.2009.68	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:214684(crynj)|taxid:214684("Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6936252|mint:MINT-7261129|imex:IM-13819-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148|mint:MINT-7261131(identity)	interpro:IPR001499(Fungal pheromone STE3 GPCR)|refseq:XP_569248.1|mint:Q5KLS3|ensemblfungi:AAW41941(transcript)|ensemblfungi:CNB04250(gene)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000755"(cytogamy)|go:"GO:0004932"(mating-type factor pheromone receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|mint:MINT-7261135(identity)	-	crc64:881B91792AE91748	-	figure legend:f5b|comment:mint|comment:The Saccharomyces cerevisiae Uniprot ID of GPa2 has been used instead of Cryptococcus neoformans one.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/09/01	2016/10/04	rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292	rogid:VabwZ2oXeqYieIPxraxepOtuEaA214684	intact-crc:6CB7768DDA278CDC|rigid:nXoUWslE2ehpZ3QhdJ4xhfpILdU	false	fusion protein:?-?(MINT-7261132)	fusion protein:?-?(MINT-7261138)|mutation increasing interaction:222-222(MINT-7261136)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)