#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P70496	uniprotkb:Q9Z2F5	intact:EBI-8604971|uniprotkb:P70497|uniprotkb:O54765|uniprotkb:Q9QWJ6|uniprotkb:O08959|uniprotkb:O35856|intact:MINT-1534671	intact:EBI-2255813	psi-mi:pld1_rat(display_long)|uniprotkb:Pld1(gene name)|psi-mi:Pld1(display_short)|uniprotkb:Choline phosphatase 1(gene name synonym)|uniprotkb:Phosphatidylcholine-hydrolyzing phospholipase D1(gene name synonym)	psi-mi:ctbp1_rat(display_long)|uniprotkb:Ctbp1(gene name)|psi-mi:Ctbp1(display_short)|uniprotkb:Bars(gene name synonym)|uniprotkb:Ctbp3(gene name synonym)|uniprotkb:C-terminal-binding protein 3(gene name synonym)|uniprotkb:50 kDa BFA-dependent ADP-ribosylation substrate(gene name synonym)|uniprotkb:BARS-50(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Haga et al. (2009)	mint:MINT-7260927|pubmed:19322195|imex:IM-13810|doi:10.1038/emboj.2009.78	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8605013|mint:MINT-7260935|imex:IM-13810-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000139"(Golgi membrane)|go:"GO:0004630"(phospholipase D activity)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048870"(cell motility)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0070290"(N-acylphosphatidylethanolamine-specific phospholipase D activity)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098981"(cholinergic synapse)|reactome:R-RNO-1483166|reactome:R-RNO-2029485|reactome:R-RNO-6798695|reactome:R-RNO-8980692|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013408|interpro:IPR016555(Phospholipase D, eukaryota)|interpro:IPR015679(Phospholipase D)|rgd:3349|refseq:NP_112254.1|interpro:IPR025202|mint:P70496|interpro:IPR036871|interpro:IPR001683(Phox-like)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|mint:MINT-7260938(identity)	rgd:2441|refseq:NP_062074.2|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|refseq:XP_017454636.1|interpro:IPR043322|interpro:IPR029753|interpro:IPR029752|mint:Q9Z2F5|interpro:IPR036291|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061025"(membrane fusion)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:1HKU|rcsb pdb:1HL3|rcsb pdb:2HU2|rcsb pdb:3GA0|reactome:R-RNO-3769402|reactome:R-RNO-3899300|reactome:R-RNO-4641265|mint:MINT-7260937(identity)	-	function:Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic|comment:mint	-	figure legend:f7a|comment:homomint|comment:mint|comment:"Rat UNIPROT ID of Ctbp1/Bars has been used instead of the   Cercopithecus aethiops one (not available)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	-	2009/09/01	2014/10/16	rogid:Bkv7ZiiK03//lKa3bxl7h1/ubIo10116	rogid:jmDuinp17W9oyIYyzM94fiBaDUE10116	intact-crc:75B4C0C8EE9B2337|rigid:0by2s+RmVjw2o7wOdu1bLuOuInY	false	flag tag:?-?(MINT-7260940)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Z2F5	uniprotkb:P70498	intact:EBI-2255813	intact:EBI-6140589|uniprotkb:O08768	psi-mi:ctbp1_rat(display_long)|uniprotkb:Ctbp1(gene name)|psi-mi:Ctbp1(display_short)|uniprotkb:Bars(gene name synonym)|uniprotkb:Ctbp3(gene name synonym)|uniprotkb:C-terminal-binding protein 3(gene name synonym)|uniprotkb:50 kDa BFA-dependent ADP-ribosylation substrate(gene name synonym)|uniprotkb:BARS-50(gene name synonym)	psi-mi:pld2_rat(display_long)|uniprotkb:Pld2(gene name)|psi-mi:Pld2(display_short)|uniprotkb:Choline phosphatase 2(gene name synonym)|uniprotkb:PLD1C(gene name synonym)|uniprotkb:Phosphatidylcholine-hydrolyzing phospholipase D2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Haga et al. (2009)	mint:MINT-7260927|pubmed:19322195|imex:IM-13810|doi:10.1038/emboj.2009.78	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8605091|mint:MINT-7260950|imex:IM-13810-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2441|refseq:NP_062074.2|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|refseq:XP_017454636.1|interpro:IPR043322|interpro:IPR029753|interpro:IPR029752|mint:Q9Z2F5|interpro:IPR036291|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061025"(membrane fusion)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:1HKU|rcsb pdb:1HL3|rcsb pdb:2HU2|rcsb pdb:3GA0|reactome:R-RNO-3769402|reactome:R-RNO-3899300|reactome:R-RNO-4641265|mint:MINT-7260956(identity)	interpro:IPR016555(Phospholipase D, eukaryota)|interpro:IPR036871|mint:P70498|rgd:3350|refseq:NP_150641.2|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001683(Phox-like)|interpro:IPR025202|interpro:IPR001849(Pleckstrin-like)|interpro:IPR015679(Phospholipase D)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0004630"(phospholipase D activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031526"(brush border membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0070290"(N-acylphosphatidylethanolamine-specific phospholipase D activity)|reactome:R-RNO-1483166|reactome:R-RNO-2029485|reactome:R-RNO-9013149|reactome:R-RNO-9013404|mint:MINT-7260952(identity)	-	-	-	figure legend:f7c|comment:homomint|comment:mint|comment:"Rat UNIPROT ID of Ctbp1/Bars has been used instead of the   Cercopithecus aethiops one (not available)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	-	2009/09/01	2014/10/16	rogid:jmDuinp17W9oyIYyzM94fiBaDUE10116	rogid:lHss1RrhpH2K9x19XTxxQoqTYG410116	intact-crc:87B652F4B9572629|rigid:o9s6m8cxbicjO50K42zLGcu+7yc	false	-	flag tag:?-?(MINT-7260953)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P70498	uniprotkb:Q9Z2F5	intact:EBI-6140589|uniprotkb:O08768	intact:EBI-2255813	psi-mi:pld2_rat(display_long)|uniprotkb:Pld2(gene name)|psi-mi:Pld2(display_short)|uniprotkb:Choline phosphatase 2(gene name synonym)|uniprotkb:PLD1C(gene name synonym)|uniprotkb:Phosphatidylcholine-hydrolyzing phospholipase D2(gene name synonym)	psi-mi:ctbp1_rat(display_long)|uniprotkb:Ctbp1(gene name)|psi-mi:Ctbp1(display_short)|uniprotkb:Bars(gene name synonym)|uniprotkb:Ctbp3(gene name synonym)|uniprotkb:C-terminal-binding protein 3(gene name synonym)|uniprotkb:50 kDa BFA-dependent ADP-ribosylation substrate(gene name synonym)|uniprotkb:BARS-50(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Haga et al. (2009)	mint:MINT-7260927|pubmed:19322195|imex:IM-13810|doi:10.1038/emboj.2009.78	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8605166|mint:MINT-7260961|imex:IM-13810-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR016555(Phospholipase D, eukaryota)|interpro:IPR036871|mint:P70498|rgd:3350|refseq:NP_150641.2|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001683(Phox-like)|interpro:IPR025202|interpro:IPR001849(Pleckstrin-like)|interpro:IPR015679(Phospholipase D)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0004630"(phospholipase D activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031526"(brush border membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0070290"(N-acylphosphatidylethanolamine-specific phospholipase D activity)|reactome:R-RNO-1483166|reactome:R-RNO-2029485|reactome:R-RNO-9013149|reactome:R-RNO-9013404|mint:MINT-7260963(identity)	rgd:2441|refseq:NP_062074.2|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|refseq:XP_017454636.1|interpro:IPR043322|interpro:IPR029753|interpro:IPR029752|mint:Q9Z2F5|interpro:IPR036291|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061025"(membrane fusion)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:1HKU|rcsb pdb:1HL3|rcsb pdb:2HU2|rcsb pdb:3GA0|reactome:R-RNO-3769402|reactome:R-RNO-3899300|reactome:R-RNO-4641265|mint:MINT-7260967(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2009/09/01	2014/10/16	rogid:lHss1RrhpH2K9x19XTxxQoqTYG410116	rogid:jmDuinp17W9oyIYyzM94fiBaDUE10116	intact-crc:C3F07A555E66F4F5|rigid:o9s6m8cxbicjO50K42zLGcu+7yc	false	green fluorescent protein tag:?-?(MINT-7260964)	tag:?-?(MINT-7260976)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)