#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9GZQ8 uniprotkb:Q9Y4P1 intact:EBI-373144|uniprotkb:Q6NW02|intact:EBI-28979688|ensembl:ENSP00000268607|ensembl:ENSP00000498476 intact:EBI-712014|uniprotkb:Q6ZUV8|uniprotkb:Q8WYM9|uniprotkb:Q96K07|uniprotkb:Q96K96|uniprotkb:Q96SZ1|uniprotkb:Q9Y2F2|uniprotkb:Q53NU4|uniprotkb:B7WNK2|ensembl:ENSP00000384259 psi-mi:mlp3b_human(display_long)|uniprotkb:MAP1LC3B(gene name)|psi-mi:MAP1LC3B(display_short)|uniprotkb:MAP1ALC3(gene name synonym)|uniprotkb:Microtubule-associated protein 1 light chain 3 beta(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 B(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym)|uniprotkb:Autophagy-related protein LC3 B(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym) psi-mi:atg4b_human(display_long)|uniprotkb:Autophagy-related protein 4 homolog B(gene name synonym)|uniprotkb:Autophagin-1(gene name synonym)|uniprotkb:Autophagy-related cysteine endopeptidase 1(gene name synonym)|uniprotkb:AUT-like 1 cysteine endopeptidase(gene name synonym)|uniprotkb:ATG4B(gene name)|psi-mi:ATG4B(display_short)|uniprotkb:APG4B(gene name synonym)|uniprotkb:AUTL1(gene name synonym)|uniprotkb:KIAA0943(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Satoo et al. (2009) mint:MINT-7261317|pubmed:19322194|imex:IM-13807|doi:10.1038/emboj.2009.80 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8603729|mint:MINT-7261325|imex:IM-13807-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000268607|ensembl:ENSP00000498476|refseq:NP_073729.1|ensembl:ENSG00000140941(gene)|ensembl:ENST00000268607(transcript)|ensembl:ENST00000650688(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097001"(ceramide binding)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|mint:Q9GZQ8|rcsb pdb:1V49|rcsb pdb:2LUE|rcsb pdb:2N9X|rcsb pdb:2ZJD|rcsb pdb:3VTU|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:3WAO|rcsb pdb:3X0W|rcsb pdb:4WAA|rcsb pdb:5D94|rcsb pdb:5DCN|rcsb pdb:5GMV|rcsb pdb:5MS2|rcsb pdb:5MS5|rcsb pdb:5MS6|rcsb pdb:5V4K|rcsb pdb:5W9A|rcsb pdb:5XAC|rcsb pdb:5XAD|rcsb pdb:5XAE|rcsb pdb:6J04|rcsb pdb:6LAN|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8854214|reactome:R-HSA-8934903|reactome:R-HSA-9664873|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-29760N|mint:MINT-7261327(identity) refseq:NP_037457.3|refseq:NP_847896.1|ensembl:ENSG00000168397(gene)|ensembl:ENST00000404914(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0051697"(protein delipidation)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR005078(Peptidase C54)|interpro:IPR032916|interpro:IPR038765|mint:Q9Y4P1|rcsb pdb:2CY7|rcsb pdb:2D1I|rcsb pdb:2Z0D|rcsb pdb:2Z0E|rcsb pdb:2ZZP|rcsb pdb:5LXH|rcsb pdb:5LXI|reactome:R-HSA-1632852|go:"GO:0006508"(proteolysis)|mint:MINT-7261328(identity) - - - comment:homomint|comment:mint|figure legend:f1 t1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/09/01 2014/10/16 rogid:yUk3FGI9csW9DNlqWkewtqM2VN09606 rogid:xSDsMshJik2bdLQ06b0kErCLxyM9606 intact-crc:4E53AB58406FF6B2|rigid:veJrcT8a34pHAYzsTC2ItBcVtDg false binding-associated region:1-120(MINT-7261335) binding-associated region:1-354(MINT-7261331) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y4P1 uniprotkb:Q9GZQ8 intact:EBI-712014|uniprotkb:Q6ZUV8|uniprotkb:Q8WYM9|uniprotkb:Q96K07|uniprotkb:Q96K96|uniprotkb:Q96SZ1|uniprotkb:Q9Y2F2|uniprotkb:Q53NU4|uniprotkb:B7WNK2|ensembl:ENSP00000384259 intact:EBI-373144|uniprotkb:Q6NW02|intact:EBI-28979688|ensembl:ENSP00000268607|ensembl:ENSP00000498476 psi-mi:atg4b_human(display_long)|uniprotkb:Autophagy-related protein 4 homolog B(gene name synonym)|uniprotkb:Autophagin-1(gene name synonym)|uniprotkb:Autophagy-related cysteine endopeptidase 1(gene name synonym)|uniprotkb:AUT-like 1 cysteine endopeptidase(gene name synonym)|uniprotkb:ATG4B(gene name)|psi-mi:ATG4B(display_short)|uniprotkb:APG4B(gene name synonym)|uniprotkb:AUTL1(gene name synonym)|uniprotkb:KIAA0943(gene name synonym) psi-mi:mlp3b_human(display_long)|uniprotkb:MAP1LC3B(gene name)|psi-mi:MAP1LC3B(display_short)|uniprotkb:MAP1ALC3(gene name synonym)|uniprotkb:Microtubule-associated protein 1 light chain 3 beta(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 B(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym)|uniprotkb:Autophagy-related protein LC3 B(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym) psi-mi:"MI:0435"(protease assay) Satoo et al. (2009) mint:MINT-7261317|pubmed:19322194|imex:IM-13807|doi:10.1038/emboj.2009.80 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0194"(cleavage reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8603756|mint:MINT-7261368|imex:IM-13807-2 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037457.3|refseq:NP_847896.1|ensembl:ENSG00000168397(gene)|ensembl:ENST00000404914(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0051697"(protein delipidation)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR005078(Peptidase C54)|interpro:IPR032916|interpro:IPR038765|mint:Q9Y4P1|rcsb pdb:2CY7|rcsb pdb:2D1I|rcsb pdb:2Z0D|rcsb pdb:2Z0E|rcsb pdb:2ZZP|rcsb pdb:5LXH|rcsb pdb:5LXI|reactome:R-HSA-1632852|go:"GO:0006508"(proteolysis)|mint:MINT-7261370(identity) ensembl:ENSP00000268607|ensembl:ENSP00000498476|refseq:NP_073729.1|ensembl:ENSG00000140941(gene)|ensembl:ENST00000268607(transcript)|ensembl:ENST00000650688(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097001"(ceramide binding)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|mint:Q9GZQ8|rcsb pdb:1V49|rcsb pdb:2LUE|rcsb pdb:2N9X|rcsb pdb:2ZJD|rcsb pdb:3VTU|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:3WAO|rcsb pdb:3X0W|rcsb pdb:4WAA|rcsb pdb:5D94|rcsb pdb:5DCN|rcsb pdb:5GMV|rcsb pdb:5MS2|rcsb pdb:5MS5|rcsb pdb:5MS6|rcsb pdb:5V4K|rcsb pdb:5W9A|rcsb pdb:5XAC|rcsb pdb:5XAD|rcsb pdb:5XAE|rcsb pdb:6J04|rcsb pdb:6LAN|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8854214|reactome:R-HSA-8934903|reactome:R-HSA-9664873|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-29760N|mint:MINT-7261374(identity) - - - figure legend:f2a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/09/01 2014/10/16 rogid:xSDsMshJik2bdLQ06b0kErCLxyM9606 rogid:yUk3FGI9csW9DNlqWkewtqM2VN09606 intact-crc:60D7E3E0EF705DED|rigid:veJrcT8a34pHAYzsTC2ItBcVtDg false - glutathione s tranferase tag:?-?(MINT-7262634) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y4P1 uniprotkb:Q9GZQ8 intact:EBI-712014|uniprotkb:Q6ZUV8|uniprotkb:Q8WYM9|uniprotkb:Q96K07|uniprotkb:Q96K96|uniprotkb:Q96SZ1|uniprotkb:Q9Y2F2|uniprotkb:Q53NU4|uniprotkb:B7WNK2|ensembl:ENSP00000384259 intact:EBI-373144|uniprotkb:Q6NW02|intact:EBI-28979688|ensembl:ENSP00000268607|ensembl:ENSP00000498476 psi-mi:atg4b_human(display_long)|uniprotkb:Autophagy-related protein 4 homolog B(gene name synonym)|uniprotkb:Autophagin-1(gene name synonym)|uniprotkb:Autophagy-related cysteine endopeptidase 1(gene name synonym)|uniprotkb:AUT-like 1 cysteine endopeptidase(gene name synonym)|uniprotkb:ATG4B(gene name)|psi-mi:ATG4B(display_short)|uniprotkb:APG4B(gene name synonym)|uniprotkb:AUTL1(gene name synonym)|uniprotkb:KIAA0943(gene name synonym) psi-mi:mlp3b_human(display_long)|uniprotkb:MAP1LC3B(gene name)|psi-mi:MAP1LC3B(display_short)|uniprotkb:MAP1ALC3(gene name synonym)|uniprotkb:Microtubule-associated protein 1 light chain 3 beta(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 B(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym)|uniprotkb:Autophagy-related protein LC3 B(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Satoo et al. (2009) mint:MINT-7261317|pubmed:19322194|imex:IM-13807|doi:10.1038/emboj.2009.80 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0194"(cleavage reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8603780|mint:MINT-7262642|imex:IM-13807-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037457.3|refseq:NP_847896.1|ensembl:ENSG00000168397(gene)|ensembl:ENST00000404914(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0051697"(protein delipidation)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR005078(Peptidase C54)|interpro:IPR032916|interpro:IPR038765|mint:Q9Y4P1|rcsb pdb:2CY7|rcsb pdb:2D1I|rcsb pdb:2Z0D|rcsb pdb:2Z0E|rcsb pdb:2ZZP|rcsb pdb:5LXH|rcsb pdb:5LXI|reactome:R-HSA-1632852|go:"GO:0006508"(proteolysis)|mint:MINT-7262644(identity) ensembl:ENSP00000268607|ensembl:ENSP00000498476|refseq:NP_073729.1|ensembl:ENSG00000140941(gene)|ensembl:ENST00000268607(transcript)|ensembl:ENST00000650688(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097001"(ceramide binding)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|mint:Q9GZQ8|rcsb pdb:1V49|rcsb pdb:2LUE|rcsb pdb:2N9X|rcsb pdb:2ZJD|rcsb pdb:3VTU|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:3WAO|rcsb pdb:3X0W|rcsb pdb:4WAA|rcsb pdb:5D94|rcsb pdb:5DCN|rcsb pdb:5GMV|rcsb pdb:5MS2|rcsb pdb:5MS5|rcsb pdb:5MS6|rcsb pdb:5V4K|rcsb pdb:5W9A|rcsb pdb:5XAC|rcsb pdb:5XAD|rcsb pdb:5XAE|rcsb pdb:6J04|rcsb pdb:6LAN|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8854214|reactome:R-HSA-8934903|reactome:R-HSA-9664873|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-29760N|mint:MINT-7262646(identity) - - - figure legend:f2a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/09/01 2014/10/16 rogid:xSDsMshJik2bdLQ06b0kErCLxyM9606 rogid:yUk3FGI9csW9DNlqWkewtqM2VN09606 intact-crc:C6859D12C1065AA3|rigid:veJrcT8a34pHAYzsTC2ItBcVtDg false binding-associated region:1-18(MINT-7262653) glutathione s tranferase tag:?-?(MINT-7262647) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)